UVRB - HALSA - GREMLIN Contacts

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UVRB - UvrABC system protein B

UniProt:	Q9HMT9	Sequences: MSDASGPLQPDRPEADVPFRVEAPFDPAGDQPDAIAELVAGYEQGAQQQTLLGVTGSGKTNTVSWVVEELQQPTLVIAHNKTLAAQLYEEFRSLFPDNAVEYFVSYYNYYQPEAYVEQTDKYIEKDASINDEIDRLRHSATRSLLTRDDVIVVASVSAIYGLGDPRNYEEMSLRVERGQSIGRDQLLAKLVDLNYDRNDVDFTQGTFRVRGDTVEVYPMYGRYPVRVEFWGDEIDRMAKLDPLEGTVESEEPAVLFHPAEHYSVPDAEMEQAIERIRTDMHERVRHFERTGDMVAAQRIEERTTFDLEMMAEAGYCSGIENYSVYLSDREVGDAPYTLLDYFPDDFLTVIDESHRTVPQIKGQYEGDKSRKDSLVDNGFRLPTAYDNRPLTFAEFADKTDRTLYVSATPGDHERAQSANVVEQIVRPTHLVDPDISIADATGQVEDLMDRIDERVARDERVLVTTLTKRMAEDLTEYLEEAGVAVEYMHDETDTLERHELVRGLRLGEYDVLVGINLLREGLDIPEVSLVAILDADQQGFLRSETSLVQTMGRAARNVNGEVVLYADETTDAMQAAIDETQRRRRIQRAFNEDHGTTPTTIEKAVGDMNLPGAETDTADVAGDAPSDEQEAALLVEDLEARMEDAASNLEFELAADIRDRMRELREAFDLDGGDAPEDPGGVAPETEDW	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	689 (649)
Sequences:	2666 (1067)
Seq/√Len:	41.9

ECOLI - UVRB
BACSU - UVRB
HALSA - UVRB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
20_R	97_D	5.737	1.00
63_V	349_V	5.525	1.00
284_V	299_I	4.944	1.00
54_V	57_S	4.918	1.00
574_Q	578_D	4.257	1.00
39_V	69_E	3.932	1.00
372_D	376_D	3.852	1.00
459_E	559_N	3.743	1.00
68_E	71_Q	3.681	1.00
589_A	593_D	3.654	1.00
277_R	311_A	3.540	1.00
214_V	229_F	3.517	1.00
216_V	227_V	3.469	1.00
48_Q	404_Y	3.459	1.00
368_K	372_D	3.393	1.00
447_L	463_V	3.357	1.00
283_R	286_H	3.307	1.00
330_E	333_D	3.305	1.00
501_V	524_I	3.301	1.00
544_E	575_A	3.283	1.00
50_T	417_S	3.237	1.00
148_D	345_D	3.163	1.00
36_A	69_E	3.145	1.00
454_R	561_E	3.129	1.00
77_I	360_I	3.127	1.00
275_R	325_Y	3.076	1.00
22_E	97_D	3.044	1.00
558_V	600_T	3.023	1.00
448_M	483_V	2.997	1.00
459_E	528_S	2.995	1.00
104_V	494_T	2.988	1.00
67_V	151_I	2.954	1.00
644_D	648_N	2.925	1.00
287_F	299_I	2.910	1.00
638_L	661_M	2.910	1.00
279_D	325_Y	2.865	1.00
21_V	65_W	2.814	1.00
639_E	665_R	2.772	1.00
227_V	234_I	2.684	1.00
551_M	576_A	2.644	1.00
431_V	588_R	2.638	1.00
486_E	509_Y	2.632	1.00
285_R	289_R	2.621	1.00
42_Y	403_L	2.617	1.00
300_E	304_T	2.586	1.00
280_M	284_V	2.580	1.00
288_E	300_E	2.554	1.00
74_T	347_L	2.533	1.00
74_T	349_V	2.523	1.00
76_V	91_F	2.516	1.00
585_R	589_A	2.512	1.00
571_D	575_A	2.511	1.00
65_W	68_E	2.497	1.00
588_R	592_E	2.452	1.00
334_A	398_K	2.449	1.00
396_A	412_H	2.435	1.00
117_E	373_S	2.407	1.00
502_R	506_L	2.405	1.00
41_G	46_A	2.399	1.00
21_V	68_E	2.349	1.00
653_L	656_D	2.313	1.00
286_H	290_T	2.307	1.00
438_A	446_D	2.286	1.00
186_L	214_V	2.266	1.00
503_G	508_E	2.251	1.00
273_I	307_L	2.220	1.00
579_E	582_R	2.189	1.00
436_S	561_E	2.163	0.99
538_Q	572_A	2.145	0.99
454_R	459_E	2.121	0.99
40_A	44_Q	2.092	0.99
434_D	561_E	2.092	0.99
186_L	229_F	2.084	0.99
635_V	664_L	2.076	0.99
187_L	214_V	2.059	0.99
350_I	357_V	2.055	0.99
660_R	663_E	2.049	0.99
42_Y	70_L	2.046	0.99
293_M	297_Q	2.031	0.99
454_R	528_S	2.027	0.99
573_M	577_I	2.022	0.99
33_D	37_E	2.004	0.99
27_P	35_I	2.000	0.99
438_A	450_R	1.992	0.99
33_D	36_A	1.987	0.99
571_D	574_Q	1.986	0.99
236_R	250_E	1.978	0.99
450_R	453_E	1.970	0.99
284_V	300_E	1.966	0.99
201_D	469_R	1.960	0.99
641_R	653_L	1.953	0.99
365_E	369_S	1.947	0.99
581_Q	585_R	1.941	0.99
28_A	590_F	1.923	0.99
453_E	456_A	1.920	0.99
396_A	416_Q	1.918	0.99
457_R	559_N	1.902	0.99
446_D	565_Y	1.887	0.99
447_L	531_A	1.885	0.99
645_A	657_I	1.883	0.99
277_R	304_T	1.870	0.99
61_N	65_W	1.870	0.99
279_D	383_T	1.867	0.98
101_E	139_S	1.856	0.98
411_D	545_T	1.847	0.98
224_P	240_L	1.840	0.98
599_T	602_E	1.811	0.98
167_N	265_P	1.805	0.98
368_K	385_Y	1.805	0.98
36_A	40_A	1.754	0.98
650_E	653_L	1.730	0.97
348_T	402_T	1.726	0.97
275_R	279_D	1.722	0.97
38_L	41_G	1.716	0.97
48_Q	416_Q	1.712	0.97
43_E	69_E	1.710	0.97
435_I	577_I	1.687	0.97
72_Q	401_R	1.680	0.97
50_T	404_Y	1.671	0.97
342_F	346_F	1.658	0.97
46_A	419_N	1.651	0.97
455_V	484_A	1.646	0.97
41_G	49_Q	1.643	0.97
357_V	361_K	1.640	0.97
39_V	43_E	1.633	0.96
324_V	386_D	1.627	0.96
270_E	311_A	1.619	0.96
63_V	403_L	1.610	0.96
448_M	481_A	1.606	0.96
483_V	511_V	1.600	0.96
273_I	311_A	1.596	0.96
175_V	234_I	1.596	0.96
225_V	254_V	1.589	0.96
173_L	193_L	1.587	0.96
141_T	261_H	1.580	0.96
286_H	299_I	1.572	0.96
173_L	186_L	1.570	0.96
375_V	385_Y	1.568	0.95
464_T	550_T	1.561	0.95
641_R	657_I	1.556	0.95
79_H	356_T	1.537	0.95
38_L	403_L	1.530	0.95
399_T	402_T	1.527	0.95
434_D	588_R	1.523	0.95
478_L	513_V	1.522	0.95
585_R	593_D	1.521	0.95
283_R	287_F	1.517	0.95
509_Y	512_L	1.509	0.94
349_V	403_L	1.503	0.94
176_E	179_Q	1.503	0.94
99_A	147_R	1.501	0.94
460_R	507_G	1.491	0.94
339_L	348_T	1.487	0.94
202_F	224_P	1.485	0.94
292_D	295_A	1.472	0.94
37_E	419_N	1.464	0.93
269_M	310_M	1.458	0.93
39_V	70_L	1.456	0.93
454_R	458_D	1.452	0.93
372_D	385_Y	1.446	0.93
72_Q	148_D	1.443	0.93
528_S	559_N	1.440	0.93
66_V	349_V	1.436	0.93
20_R	68_E	1.428	0.93
294_V	299_I	1.427	0.93
631_A	661_M	1.418	0.92
455_V	483_V	1.397	0.92
63_V	405_V	1.394	0.92
634_L	637_D	1.388	0.92
441_T	567_D	1.384	0.91
196_D	206_T	1.384	0.91
551_M	564_L	1.379	0.91
189_K	192_D	1.377	0.91
76_V	153_V	1.368	0.91
281_H	285_R	1.366	0.91
266_D	270_E	1.364	0.91
364_Y	391_T	1.355	0.91
187_L	191_V	1.352	0.90
577_I	581_Q	1.344	0.90
639_E	643_E	1.341	0.90
72_Q	349_V	1.338	0.90
139_S	143_S	1.330	0.90
284_V	288_E	1.326	0.90
72_Q	345_D	1.315	0.89
39_V	66_V	1.314	0.89
187_L	209_V	1.312	0.89
484_A	508_E	1.307	0.89
296_A	300_E	1.305	0.89
95_F	151_I	1.299	0.89
175_V	186_L	1.292	0.88
411_D	415_A	1.288	0.88
453_E	457_R	1.281	0.88
636_E	639_E	1.277	0.88
284_V	287_F	1.277	0.88
228_E	236_R	1.275	0.88
589_A	592_E	1.268	0.87
282_E	286_H	1.267	0.87
450_R	563_V	1.257	0.87
414_R	420_V	1.254	0.87
181_I	186_L	1.250	0.87
93_S	606_G	1.247	0.86
350_I	402_T	1.246	0.86
564_L	577_I	1.243	0.86
637_D	641_R	1.243	0.86
228_E	238_A	1.243	0.86
348_T	399_T	1.238	0.86
43_E	70_L	1.235	0.86
424_I	586_I	1.235	0.86
362_G	391_T	1.227	0.85
357_V	392_F	1.221	0.85
463_V	533_L	1.217	0.85
635_V	661_M	1.202	0.84
437_I	577_I	1.189	0.84
274_E	278_T	1.185	0.83
506_L	605_V	1.182	0.83
144_L	150_V	1.181	0.83
239_K	249_S	1.180	0.83
538_Q	570_T	1.175	0.83
324_V	331_V	1.167	0.82
70_L	74_T	1.167	0.82
462_L	524_I	1.165	0.82
167_N	268_E	1.162	0.82
373_S	385_Y	1.161	0.82
199_D	210_R	1.161	0.82
37_E	421_V	1.157	0.82
627_D	630_E	1.157	0.82
414_R	417_S	1.154	0.82
209_V	214_V	1.152	0.82
271_Q	275_R	1.148	0.81
46_A	418_A	1.146	0.81
279_D	282_E	1.144	0.81
76_V	151_I	1.143	0.81
569_T	574_Q	1.142	0.81
177_R	252_P	1.141	0.81
139_S	152_V	1.133	0.81
278_T	281_H	1.130	0.80
325_Y	383_T	1.130	0.80
498_H	608_M	1.128	0.80
79_H	545_T	1.121	0.80
277_R	307_L	1.120	0.80
578_D	581_Q	1.119	0.80
435_I	551_M	1.118	0.80
146_T	257_H	1.112	0.79
339_L	395_F	1.109	0.79
134_D	204_Q	1.108	0.79
50_T	416_Q	1.108	0.79
175_V	227_V	1.103	0.79
119_T	317_S	1.100	0.79
202_F	217_Y	1.099	0.78
132_E	136_L	1.097	0.78
449_D	452_D	1.093	0.78
72_Q	347_L	1.093	0.78
327_S	336_Y	1.091	0.78
63_V	66_V	1.088	0.78
33_D	586_I	1.085	0.78
484_A	507_G	1.081	0.77
412_H	416_Q	1.078	0.77
557_N	600_T	1.075	0.77
67_V	76_V	1.072	0.77
230_W	235_D	1.072	0.77
569_T	573_M	1.071	0.77
167_N	170_E	1.068	0.76
357_V	360_I	1.065	0.76
569_T	577_I	1.058	0.76
360_I	399_T	1.055	0.76
434_D	581_Q	1.055	0.76
453_E	561_E	1.052	0.75
417_S	420_V	1.052	0.75
138_H	168_Y	1.050	0.75
592_E	595_G	1.048	0.75
26_D	65_W	1.047	0.75
361_K	411_D	1.044	0.75
88_Y	92_R	1.043	0.75
224_P	242_P	1.037	0.74
277_R	281_H	1.037	0.74
72_Q	400_D	1.035	0.74
176_E	253_A	1.035	0.74
203_T	206_T	1.027	0.74
269_M	326_L	1.026	0.73
77_I	348_T	1.025	0.73
275_R	328_D	1.021	0.73
503_G	509_Y	1.018	0.73
410_G	417_S	1.017	0.73
448_M	478_L	1.017	0.73
551_M	580_T	1.016	0.73
77_I	350_I	1.014	0.73
275_R	278_T	1.014	0.73
115_Y	120_D	1.010	0.72
435_I	564_L	1.008	0.72
458_D	461_V	1.004	0.72
171_M	265_P	1.001	0.72
65_W	69_E	1.001	0.72
286_H	289_R	1.001	0.72
486_E	503_G	0.997	0.71
439_D	567_D	0.996	0.71
175_V	237_M	0.995	0.71
644_D	647_S	0.994	0.71
532_I	564_L	0.994	0.71
437_I	573_M	0.990	0.71
278_T	282_E	0.989	0.71
279_D	326_L	0.988	0.71
78_A	87_L	0.988	0.71
42_Y	401_R	0.988	0.71
343_P	400_D	0.987	0.71
569_T	578_D	0.987	0.71
656_D	660_R	0.980	0.70
138_H	220_Y	0.977	0.70
431_V	558_V	0.977	0.70
468_K	490_D	0.977	0.70
18_P	71_Q	0.975	0.70
239_K	251_E	0.975	0.70
228_E	235_D	0.973	0.69
365_E	391_T	0.972	0.69
21_V	71_Q	0.965	0.69
268_E	271_Q	0.964	0.69
488_M	492_T	0.958	0.68
79_H	355_R	0.957	0.68
181_I	234_I	0.956	0.68
284_V	296_A	0.956	0.68
288_E	296_A	0.954	0.68
632_A	636_E	0.953	0.68
645_A	653_L	0.953	0.68
41_G	419_N	0.949	0.67
140_A	152_V	0.948	0.67
505_R	526_E	0.946	0.67
606_G	609_N	0.942	0.67
478_L	481_A	0.942	0.67
294_V	301_E	0.941	0.67
451_I	463_V	0.940	0.67
274_E	277_R	0.939	0.67
124_E	301_E	0.939	0.67
454_R	461_V	0.937	0.66
229_F	234_I	0.936	0.66
63_V	76_V	0.936	0.66
41_G	403_L	0.935	0.66
437_I	566_A	0.931	0.66
290_T	376_D	0.930	0.66
148_D	401_R	0.927	0.66
41_G	70_L	0.925	0.65
499_E	502_R	0.921	0.65
182_G	188_A	0.914	0.65
435_I	576_A	0.914	0.65
662_R	665_R	0.910	0.64
492_T	500_L	0.906	0.64
134_D	140_A	0.906	0.64
272_A	276_I	0.905	0.64
164_D	327_S	0.896	0.63
42_Y	347_L	0.895	0.63
455_V	511_V	0.894	0.63
288_E	291_G	0.893	0.63
37_E	40_A	0.888	0.62
285_R	288_E	0.887	0.62
410_G	545_T	0.886	0.62
638_L	657_I	0.885	0.62
339_L	346_F	0.881	0.62
230_W	233_E	0.878	0.61
78_A	138_H	0.877	0.61
323_S	367_D	0.875	0.61
74_T	400_D	0.874	0.61
626_S	630_E	0.869	0.61
468_K	491_E	0.867	0.60
177_R	250_E	0.866	0.60
448_M	452_D	0.865	0.60
348_T	400_D	0.865	0.60
142_R	146_T	0.862	0.60
171_M	263_S	0.860	0.60
271_Q	325_Y	0.859	0.60
223_Y	239_K	0.857	0.60
362_G	365_E	0.854	0.59
152_V	341_Y	0.854	0.59
260_E	315_Y	0.851	0.59
396_A	404_Y	0.848	0.59
77_I	356_T	0.846	0.59
639_E	661_M	0.845	0.58
447_L	533_L	0.843	0.58
68_E	97_D	0.843	0.58
440_A	444_V	0.841	0.58
369_S	373_S	0.837	0.58
186_L	227_V	0.835	0.58
212_D	231_G	0.835	0.58
162_L	315_Y	0.834	0.57
223_Y	248_E	0.832	0.57
465_T	533_L	0.831	0.57
392_F	412_H	0.830	0.57
142_R	220_Y	0.828	0.57
79_H	357_V	0.827	0.57
272_A	325_Y	0.823	0.56
49_Q	70_L	0.821	0.56
361_K	365_E	0.821	0.56
451_I	511_V	0.818	0.56
564_L	576_A	0.815	0.56
50_T	396_A	0.815	0.56
469_R	473_D	0.811	0.55
42_Y	72_Q	0.811	0.55
181_I	189_K	0.809	0.55
404_Y	416_Q	0.808	0.55
471_A	484_A	0.808	0.55
93_S	603_K	0.807	0.55
127_A	287_F	0.807	0.55
451_I	461_V	0.806	0.55
350_I	360_I	0.805	0.55
178_G	233_E	0.803	0.55
662_R	666_E	0.801	0.54
581_Q	588_R	0.800	0.54
655_A	659_D	0.800	0.54
530_V	550_T	0.800	0.54
203_T	469_R	0.800	0.54
175_V	256_F	0.798	0.54
461_V	464_T	0.798	0.54
225_V	256_F	0.797	0.54
152_V	597_T	0.796	0.54
431_V	436_S	0.796	0.54
134_D	152_V	0.793	0.54
25_F	603_K	0.793	0.54
548_V	576_A	0.792	0.54
217_Y	224_P	0.791	0.53
477_Y	481_A	0.790	0.53
307_L	311_A	0.790	0.53
284_V	294_V	0.790	0.53
283_R	382_P	0.786	0.53
231_G	235_D	0.786	0.53
495_L	498_H	0.785	0.53
38_L	49_Q	0.785	0.53
168_Y	337_T	0.784	0.53
452_D	456_A	0.784	0.53
77_I	402_T	0.783	0.53
479_E	485_V	0.782	0.53
438_A	563_V	0.781	0.52
528_S	560_G	0.780	0.52
273_I	310_M	0.780	0.52
101_E	143_S	0.780	0.52
26_D	61_N	0.779	0.52
551_M	562_V	0.777	0.52
77_I	395_F	0.777	0.52
450_R	561_E	0.775	0.52
143_S	491_E	0.774	0.52
634_L	660_R	0.772	0.52
91_F	349_V	0.772	0.52
183_R	214_V	0.771	0.52
214_V	237_M	0.769	0.51
425_V	442_G	0.766	0.51
183_R	187_L	0.766	0.51
247_V	250_E	0.765	0.51
216_V	256_F	0.761	0.51
225_V	239_K	0.761	0.51
493_D	496_E	0.761	0.51
437_I	574_Q	0.760	0.51
78_A	260_E	0.759	0.50
127_A	315_Y	0.759	0.50
459_E	560_G	0.758	0.50
164_D	268_E	0.756	0.50
283_R	376_D	0.756	0.50
174_R	253_A	0.755	0.50
285_R	589_A	0.755	0.50
77_I	158_A	0.752	0.50
592_E	599_T	0.751	0.50
164_D	263_S	0.751	0.50
486_E	512_L	0.750	0.50
25_F	65_W	0.749	0.49
362_G	411_D	0.749	0.49
360_I	402_T	0.749	0.49
50_T	418_A	0.749	0.49
524_I	558_V	0.746	0.49
451_I	458_D	0.746	0.49
126_D	317_S	0.745	0.49
89_E	92_R	0.745	0.49
528_S	561_E	0.743	0.49
183_R	209_V	0.743	0.49
148_D	400_D	0.743	0.49
357_V	402_T	0.742	0.49
597_T	604_A	0.741	0.49
429_H	596_T	0.741	0.49
138_H	261_H	0.738	0.48
451_I	455_V	0.737	0.48
158_A	339_L	0.736	0.48
582_R	603_K	0.734	0.48
26_D	68_E	0.733	0.48
438_A	561_E	0.731	0.48
21_V	26_D	0.730	0.48
136_L	496_E	0.730	0.48
502_R	607_D	0.726	0.47
259_A	342_F	0.726	0.47
72_Q	343_P	0.725	0.47
88_Y	138_H	0.724	0.47
281_H	300_E	0.723	0.47
475_T	485_V	0.723	0.47
138_H	260_E	0.722	0.47
24_P	411_D	0.720	0.47
286_H	292_D	0.720	0.47
576_A	582_R	0.718	0.47
284_V	325_Y	0.718	0.47
287_F	290_T	0.717	0.47
464_T	522_L	0.716	0.46
609_N	612_G	0.715	0.46
145_L	341_Y	0.715	0.46
50_T	414_R	0.714	0.46
611_P	614_E	0.713	0.46
264_V	445_E	0.713	0.46
138_H	145_L	0.711	0.46
625_P	628_E	0.710	0.46
225_V	237_M	0.710	0.46
558_V	599_T	0.710	0.46
302_R	375_V	0.710	0.46
36_A	589_A	0.709	0.46
348_T	360_I	0.709	0.46
612_G	615_T	0.703	0.45
544_E	571_D	0.703	0.45
329_R	460_R	0.703	0.45
190_L	227_V	0.702	0.45
334_A	337_T	0.702	0.45
287_F	292_D	0.701	0.45
362_G	410_G	0.701	0.45
303_T	307_L	0.701	0.45
152_V	253_A	0.700	0.45
253_A	444_V	0.700	0.45
485_V	513_V	0.698	0.45
136_L	255_L	0.698	0.45
208_R	215_E	0.697	0.45
138_H	219_M	0.696	0.45
79_H	145_L	0.694	0.44
237_M	251_E	0.694	0.44
524_I	557_N	0.693	0.44
38_L	62_T	0.693	0.44
24_P	602_E	0.692	0.44
133_I	312_E	0.691	0.44
458_D	602_E	0.690	0.44
163_G	261_H	0.690	0.44
393_A	396_A	0.689	0.44
69_E	74_T	0.689	0.44
39_V	42_Y	0.689	0.44
173_L	189_K	0.688	0.44
75_L	158_A	0.688	0.44
522_L	550_T	0.688	0.44
24_P	604_A	0.687	0.44
438_A	565_Y	0.687	0.44
40_A	43_E	0.686	0.44
251_E	254_V	0.686	0.44
141_T	163_G	0.686	0.44
430_L	515_I	0.685	0.44
242_P	469_R	0.685	0.44
446_D	450_R	0.684	0.43
663_E	666_E	0.681	0.43
458_D	595_G	0.680	0.43
270_E	274_E	0.679	0.43
365_E	393_A	0.679	0.43
292_D	299_I	0.677	0.43
241_D	246_T	0.676	0.43
138_H	142_R	0.676	0.43
191_V	207_F	0.676	0.43
162_L	165_P	0.675	0.43
99_A	150_V	0.674	0.43
134_D	138_H	0.674	0.43
460_R	484_A	0.674	0.43
220_Y	240_L	0.674	0.43
375_V	384_A	0.673	0.42
89_E	608_M	0.673	0.42
451_I	483_V	0.673	0.42
173_L	214_V	0.672	0.42
357_V	412_H	0.671	0.42
488_M	501_V	0.671	0.42
134_D	586_I	0.671	0.42
221_G	239_K	0.670	0.42
75_L	339_L	0.670	0.42
603_K	606_G	0.670	0.42
162_L	261_H	0.669	0.42
109_Y	124_E	0.668	0.42
576_A	579_E	0.667	0.42
25_F	118_Q	0.667	0.42
291_G	297_Q	0.665	0.42
91_F	153_V	0.663	0.42
66_V	117_E	0.662	0.41
79_H	87_L	0.662	0.41
260_E	263_S	0.662	0.41
76_V	349_V	0.661	0.41
585_R	592_E	0.660	0.41
117_E	377_N	0.660	0.41
249_S	611_P	0.660	0.41
463_V	595_G	0.659	0.41
645_A	650_E	0.658	0.41
653_L	657_I	0.655	0.41
334_A	390_L	0.655	0.41
269_M	273_I	0.655	0.41
25_F	79_H	0.655	0.41
275_R	331_V	0.655	0.41
99_A	143_S	0.654	0.41
111_Q	126_D	0.653	0.41
52_L	66_V	0.650	0.40
545_T	575_A	0.650	0.40
246_T	442_G	0.650	0.40
134_D	142_R	0.648	0.40
463_V	531_A	0.648	0.40
148_D	343_P	0.646	0.40
71_Q	74_T	0.646	0.40
344_D	400_D	0.645	0.40
239_K	254_V	0.645	0.40
77_I	238_A	0.644	0.40
455_V	461_V	0.643	0.40
465_T	471_A	0.643	0.40
264_V	269_M	0.643	0.40
568_E	571_D	0.643	0.40
198_N	297_Q	0.643	0.40
73_P	343_P	0.643	0.40
642_M	646_A	0.643	0.40
257_H	341_Y	0.642	0.40
362_G	495_L	0.641	0.40
107_Y	157_S	0.641	0.40
287_F	331_V	0.641	0.40
631_A	634_L	0.640	0.39
435_I	573_M	0.639	0.39
23_A	26_D	0.638	0.39
268_E	328_D	0.638	0.39
21_V	39_V	0.637	0.39
340_D	398_K	0.637	0.39
181_I	229_F	0.637	0.39
301_E	317_S	0.636	0.39
422_E	582_R	0.636	0.39
21_V	61_N	0.635	0.39
582_R	586_I	0.634	0.39
215_E	240_L	0.634	0.39
218_P	341_Y	0.634	0.39
91_F	346_F	0.632	0.39
292_D	376_D	0.632	0.39
503_G	506_L	0.632	0.39
362_G	572_A	0.632	0.39
262_Y	425_V	0.631	0.39
492_T	496_E	0.631	0.39
364_Y	372_D	0.631	0.39
281_H	304_T	0.631	0.39
613_A	616_D	0.630	0.39
29_G	32_P	0.629	0.38
529_L	563_V	0.629	0.38
579_E	603_K	0.629	0.38
280_M	287_F	0.629	0.38
502_R	605_V	0.629	0.38
444_V	478_L	0.628	0.38
188_A	192_D	0.627	0.38
185_Q	189_K	0.627	0.38
373_S	491_E	0.626	0.38
28_A	122_Y	0.626	0.38
133_I	356_T	0.625	0.38
431_V	434_D	0.625	0.38
77_I	357_V	0.624	0.38
141_T	162_L	0.623	0.38
107_Y	141_T	0.623	0.38
116_V	607_D	0.621	0.38
127_A	385_Y	0.620	0.38
92_R	662_R	0.620	0.38
339_L	342_F	0.619	0.38
237_M	256_F	0.619	0.38
640_A	644_D	0.618	0.37
63_V	91_F	0.618	0.37
455_V	509_Y	0.618	0.37
468_K	509_Y	0.618	0.37
54_V	63_V	0.618	0.37
43_E	46_A	0.618	0.37
262_Y	485_V	0.616	0.37
488_M	494_T	0.616	0.37
633_L	640_A	0.616	0.37
142_R	172_S	0.616	0.37
63_V	151_I	0.615	0.37
339_L	390_L	0.614	0.37
471_A	488_M	0.613	0.37
24_P	65_W	0.613	0.37
471_A	509_Y	0.611	0.37
238_A	250_E	0.611	0.37
462_L	522_L	0.611	0.37
486_E	492_T	0.611	0.37
641_R	645_A	0.611	0.37
47_Q	399_T	0.610	0.37
88_Y	524_I	0.610	0.37
458_D	528_S	0.609	0.37
85_A	493_D	0.609	0.37
114_A	326_L	0.608	0.37
491_E	512_L	0.608	0.37
79_H	144_L	0.608	0.37
77_I	154_A	0.607	0.37
454_R	457_R	0.606	0.36
280_M	299_I	0.606	0.36
208_R	245_G	0.605	0.36
572_A	651_F	0.605	0.36
350_I	412_H	0.604	0.36
106_Y	157_S	0.603	0.36
476_E	479_E	0.603	0.36
145_L	152_V	0.602	0.36
597_T	600_T	0.602	0.36
62_T	423_Q	0.601	0.36
260_E	515_I	0.601	0.36
89_E	502_R	0.600	0.36
186_L	189_K	0.599	0.36
157_S	163_G	0.599	0.36
373_S	391_T	0.598	0.36
33_D	421_V	0.598	0.36
64_S	85_A	0.598	0.36
502_R	515_I	0.597	0.36
44_Q	47_Q	0.597	0.36
121_K	133_I	0.597	0.36
162_L	169_E	0.596	0.36
357_V	530_V	0.596	0.36
135_R	193_L	0.596	0.36
410_G	414_R	0.595	0.35
43_E	74_T	0.595	0.35
327_S	333_D	0.595	0.35
127_A	293_M	0.595	0.35
572_A	575_A	0.594	0.35
650_E	665_R	0.594	0.35
235_D	592_E	0.594	0.35
166_R	170_E	0.593	0.35
434_D	559_N	0.593	0.35
198_N	243_L	0.593	0.35
628_E	632_A	0.593	0.35
91_F	151_I	0.591	0.35
33_D	424_I	0.590	0.35
601_I	604_A	0.590	0.35
77_I	143_S	0.589	0.35
310_M	319_I	0.588	0.35
78_A	545_T	0.588	0.35
251_E	611_P	0.587	0.35
457_R	528_S	0.587	0.35
79_H	132_E	0.586	0.35
287_F	297_Q	0.586	0.35
107_Y	129_I	0.586	0.35
145_L	495_L	0.584	0.35
470_M	474_L	0.584	0.35
36_A	43_E	0.584	0.35
57_S	63_V	0.583	0.34
395_F	527_V	0.583	0.34
303_T	325_Y	0.583	0.34
455_V	510_D	0.583	0.34
280_M	304_T	0.582	0.34
161_G	343_P	0.581	0.34
63_V	70_L	0.581	0.34
166_R	172_S	0.581	0.34
145_L	287_F	0.581	0.34
630_E	633_L	0.581	0.34
116_V	219_M	0.581	0.34
74_T	79_H	0.580	0.34
337_T	609_N	0.580	0.34
135_R	545_T	0.580	0.34
193_L	263_S	0.580	0.34
21_V	69_E	0.579	0.34
89_E	606_G	0.579	0.34
500_L	509_Y	0.579	0.34
626_S	634_L	0.579	0.34
25_F	76_V	0.578	0.34
264_V	326_L	0.578	0.34
545_T	600_T	0.578	0.34
19_F	74_T	0.576	0.34
461_V	550_T	0.575	0.34
163_G	309_M	0.574	0.34
491_E	513_V	0.574	0.34
155_S	391_T	0.573	0.34
65_W	71_Q	0.573	0.34
390_L	398_K	0.573	0.34
48_Q	143_S	0.572	0.34
373_S	377_N	0.572	0.34
345_D	400_D	0.572	0.34
25_F	94_L	0.572	0.34
122_Y	661_M	0.572	0.34
548_V	551_M	0.572	0.34
140_A	261_H	0.571	0.33
18_P	68_E	0.570	0.33
364_Y	369_S	0.570	0.33
255_L	264_V	0.570	0.33
448_M	513_V	0.569	0.33
185_Q	188_A	0.569	0.33
442_G	449_D	0.569	0.33
75_L	342_F	0.568	0.33
165_P	384_A	0.568	0.33
279_D	283_R	0.567	0.33
244_E	478_L	0.567	0.33
579_E	583_R	0.565	0.33
154_A	168_Y	0.565	0.33
227_V	256_F	0.565	0.33
616_D	619_D	0.564	0.33
262_Y	315_Y	0.564	0.33
395_F	404_Y	0.563	0.33
461_V	512_L	0.562	0.33
631_A	664_L	0.562	0.33
395_F	465_T	0.562	0.33
644_D	650_E	0.561	0.33
87_L	91_F	0.561	0.33
230_W	470_M	0.561	0.33
633_L	638_L	0.561	0.33
174_R	255_L	0.560	0.33
179_Q	234_I	0.559	0.32
431_V	575_A	0.559	0.32
99_A	164_D	0.559	0.32
33_D	411_D	0.558	0.32
132_E	501_V	0.557	0.32
638_L	652_E	0.557	0.32
317_S	373_S	0.557	0.32
524_I	564_L	0.557	0.32
237_M	557_N	0.556	0.32
154_A	225_V	0.556	0.32
60_T	63_V	0.555	0.32
291_G	294_V	0.554	0.32
399_T	404_Y	0.554	0.32
172_S	255_L	0.554	0.32
132_E	524_I	0.553	0.32
94_L	138_H	0.553	0.32
243_L	369_S	0.553	0.32
586_I	589_A	0.553	0.32
157_S	309_M	0.552	0.32
43_E	72_Q	0.552	0.32
120_D	301_E	0.551	0.32
89_E	609_N	0.551	0.32
425_V	432_D	0.551	0.32
440_A	567_D	0.550	0.32
50_T	164_D	0.550	0.32
212_D	230_W	0.548	0.32
452_D	483_V	0.547	0.31
268_E	275_R	0.547	0.31
76_V	469_R	0.546	0.31
124_E	129_I	0.546	0.31
585_R	588_R	0.546	0.31
431_V	576_A	0.545	0.31
28_A	421_V	0.545	0.31
131_D	204_Q	0.545	0.31
350_I	618_A	0.545	0.31
645_A	648_N	0.544	0.31
122_Y	373_S	0.544	0.31
403_L	597_T	0.543	0.31
171_M	228_E	0.543	0.31
204_Q	260_E	0.543	0.31
524_I	527_V	0.543	0.31
72_Q	341_Y	0.542	0.31
330_E	334_A	0.541	0.31
357_V	524_I	0.541	0.31
259_A	317_S	0.541	0.31
28_A	32_P	0.541	0.31
275_R	310_M	0.541	0.31
41_G	301_E	0.540	0.31
74_T	150_V	0.539	0.31
395_F	399_T	0.539	0.31
167_N	327_S	0.539	0.31
175_V	193_L	0.538	0.31
337_T	398_K	0.538	0.31
79_H	411_D	0.538	0.31
150_V	481_A	0.538	0.31
162_L	167_N	0.537	0.31
661_M	665_R	0.537	0.31
416_Q	513_V	0.537	0.31
471_A	492_T	0.537	0.31
641_R	644_D	0.536	0.31
537_Q	550_T	0.536	0.31
70_L	403_L	0.536	0.31
116_V	377_N	0.536	0.31
168_Y	261_H	0.536	0.31
142_R	169_E	0.535	0.31
99_A	106_Y	0.535	0.31
164_D	377_N	0.535	0.31
22_E	71_Q	0.535	0.31
355_R	358_P	0.535	0.31
455_V	513_V	0.534	0.30
451_I	454_R	0.534	0.30
57_S	365_E	0.534	0.30
447_L	529_L	0.533	0.30
163_G	462_L	0.533	0.30
650_E	661_M	0.532	0.30
122_Y	299_I	0.532	0.30
116_V	310_M	0.531	0.30
414_R	545_T	0.531	0.30
271_Q	328_D	0.531	0.30
236_R	515_I	0.531	0.30
48_Q	396_A	0.530	0.30
140_A	368_K	0.530	0.30
610_L	613_A	0.530	0.30
43_E	592_E	0.529	0.30
349_V	524_I	0.529	0.30
217_Y	221_G	0.528	0.30
21_V	95_F	0.528	0.30
158_A	259_A	0.527	0.30
213_T	228_E	0.527	0.30
310_M	313_A	0.527	0.30
118_Q	545_T	0.526	0.30
337_T	543_S	0.526	0.30
217_Y	494_T	0.526	0.30
373_S	376_D	0.525	0.30
225_V	395_F	0.524	0.30
85_A	498_H	0.524	0.30
337_T	473_D	0.524	0.30
585_R	665_R	0.524	0.30
102_Y	347_L	0.524	0.30
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195_Y	530_V	0.523	0.30
303_T	383_T	0.523	0.30
107_Y	142_R	0.523	0.30
91_F	132_E	0.522	0.29
220_Y	257_H	0.522	0.29
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227_V	630_E	0.521	0.29
68_E	246_T	0.521	0.29
138_H	141_T	0.521	0.29
219_M	242_P	0.521	0.29
221_G	225_V	0.520	0.29
462_L	543_S	0.520	0.29
375_V	527_V	0.520	0.29
403_L	508_E	0.520	0.29
449_D	453_E	0.520	0.29
573_M	579_E	0.520	0.29
657_I	661_M	0.520	0.29
310_M	445_E	0.519	0.29
479_E	486_E	0.518	0.29
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479_E	499_E	0.518	0.29
484_A	509_Y	0.517	0.29
615_T	621_A	0.517	0.29
161_G	337_T	0.517	0.29
616_D	621_A	0.516	0.29
568_E	574_Q	0.516	0.29
163_G	197_R	0.516	0.29
221_G	488_M	0.516	0.29
585_R	597_T	0.516	0.29
449_D	481_A	0.515	0.29
515_I	524_I	0.515	0.29
447_L	451_I	0.515	0.29
78_A	262_Y	0.515	0.29
39_V	68_E	0.515	0.29
30_D	34_A	0.514	0.29
162_L	548_V	0.514	0.29
252_P	262_Y	0.514	0.29
288_E	299_I	0.514	0.29
346_F	400_D	0.513	0.29
310_M	499_E	0.513	0.29
124_E	300_E	0.513	0.29
127_A	326_L	0.513	0.29
106_Y	109_Y	0.513	0.29
634_L	641_R	0.512	0.29
169_E	172_S	0.512	0.29
140_A	204_Q	0.512	0.29
392_F	418_A	0.511	0.29
265_P	326_L	0.511	0.29
97_D	457_R	0.511	0.29
21_V	97_D	0.511	0.29
155_S	608_M	0.511	0.29
70_L	349_V	0.511	0.29
134_D	503_G	0.510	0.29
461_V	522_L	0.510	0.29
175_V	181_I	0.510	0.29
37_E	69_E	0.509	0.28
362_G	397_D	0.509	0.28
265_P	327_S	0.508	0.28
116_V	385_Y	0.507	0.28
134_D	155_S	0.507	0.28
377_N	648_N	0.507	0.28
33_D	644_D	0.507	0.28
122_Y	590_F	0.506	0.28
238_A	249_S	0.506	0.28
134_D	158_A	0.506	0.28
262_Y	334_A	0.505	0.28
202_F	208_R	0.504	0.28
282_E	325_Y	0.504	0.28
140_A	265_P	0.504	0.28
538_Q	571_D	0.503	0.28
376_D	575_A	0.503	0.28
361_K	393_A	0.503	0.28
138_H	498_H	0.503	0.28
313_A	404_Y	0.503	0.28
220_Y	342_F	0.503	0.28
297_Q	301_E	0.503	0.28
176_E	220_Y	0.502	0.28
109_Y	157_S	0.502	0.28
88_Y	171_M	0.502	0.28
170_E	593_D	0.502	0.28
340_D	395_F	0.502	0.28
299_I	414_R	0.502	0.28
46_A	421_V	0.502	0.28
66_V	421_V	0.501	0.28
504_L	507_G	0.501	0.28
307_L	325_Y	0.501	0.28
138_H	184_D	0.500	0.28
425_V	551_M	0.500	0.28

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2d7dA	2	0.9071	100	0.502	Contact Map
1c4oA	1	0.717	100	0.508	Contact Map
2eyqA	1	0.807	100	0.733	Contact Map
3hjhA	1	0.6241	100	0.743	Contact Map
4gl2A	1	0.7199	100	0.887	Contact Map
4a4zA	1	0.6226	100	0.894	Contact Map
4nl4H	1	0.5951	100	0.903	Contact Map
1gm5A	1	0.5472	100	0.904	Contact Map
2ocaA	1	0.5225	100	0.906	Contact Map
3fhoA	2	0.418	100	0.906	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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