GREMLIN Database
UVRB - UvrABC system protein B
UniProt: Q9HMT9 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 689 (649)
Sequences: 2666 (1067)
Seq/√Len: 41.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
20_R97_D5.7371.00
63_V349_V5.5251.00
284_V299_I4.9441.00
54_V57_S4.9181.00
574_Q578_D4.2571.00
39_V69_E3.9321.00
372_D376_D3.8521.00
459_E559_N3.7431.00
68_E71_Q3.6811.00
589_A593_D3.6541.00
277_R311_A3.5401.00
214_V229_F3.5171.00
216_V227_V3.4691.00
48_Q404_Y3.4591.00
368_K372_D3.3931.00
447_L463_V3.3571.00
283_R286_H3.3071.00
330_E333_D3.3051.00
501_V524_I3.3011.00
544_E575_A3.2831.00
50_T417_S3.2371.00
148_D345_D3.1631.00
36_A69_E3.1451.00
454_R561_E3.1291.00
77_I360_I3.1271.00
275_R325_Y3.0761.00
22_E97_D3.0441.00
558_V600_T3.0231.00
448_M483_V2.9971.00
459_E528_S2.9951.00
104_V494_T2.9881.00
67_V151_I2.9541.00
644_D648_N2.9251.00
287_F299_I2.9101.00
638_L661_M2.9101.00
279_D325_Y2.8651.00
21_V65_W2.8141.00
639_E665_R2.7721.00
227_V234_I2.6841.00
551_M576_A2.6441.00
431_V588_R2.6381.00
486_E509_Y2.6321.00
285_R289_R2.6211.00
42_Y403_L2.6171.00
300_E304_T2.5861.00
280_M284_V2.5801.00
288_E300_E2.5541.00
74_T347_L2.5331.00
74_T349_V2.5231.00
76_V91_F2.5161.00
585_R589_A2.5121.00
571_D575_A2.5111.00
65_W68_E2.4971.00
588_R592_E2.4521.00
334_A398_K2.4491.00
396_A412_H2.4351.00
117_E373_S2.4071.00
502_R506_L2.4051.00
41_G46_A2.3991.00
21_V68_E2.3491.00
653_L656_D2.3131.00
286_H290_T2.3071.00
438_A446_D2.2861.00
186_L214_V2.2661.00
503_G508_E2.2511.00
273_I307_L2.2201.00
579_E582_R2.1891.00
436_S561_E2.1630.99
538_Q572_A2.1450.99
454_R459_E2.1210.99
40_A44_Q2.0920.99
434_D561_E2.0920.99
186_L229_F2.0840.99
635_V664_L2.0760.99
187_L214_V2.0590.99
350_I357_V2.0550.99
660_R663_E2.0490.99
42_Y70_L2.0460.99
293_M297_Q2.0310.99
454_R528_S2.0270.99
573_M577_I2.0220.99
33_D37_E2.0040.99
27_P35_I2.0000.99
438_A450_R1.9920.99
33_D36_A1.9870.99
571_D574_Q1.9860.99
236_R250_E1.9780.99
450_R453_E1.9700.99
284_V300_E1.9660.99
201_D469_R1.9600.99
641_R653_L1.9530.99
365_E369_S1.9470.99
581_Q585_R1.9410.99
28_A590_F1.9230.99
453_E456_A1.9200.99
396_A416_Q1.9180.99
457_R559_N1.9020.99
446_D565_Y1.8870.99
447_L531_A1.8850.99
645_A657_I1.8830.99
277_R304_T1.8700.99
61_N65_W1.8700.99
279_D383_T1.8670.98
101_E139_S1.8560.98
411_D545_T1.8470.98
224_P240_L1.8400.98
599_T602_E1.8110.98
167_N265_P1.8050.98
368_K385_Y1.8050.98
36_A40_A1.7540.98
650_E653_L1.7300.97
348_T402_T1.7260.97
275_R279_D1.7220.97
38_L41_G1.7160.97
48_Q416_Q1.7120.97
43_E69_E1.7100.97
435_I577_I1.6870.97
72_Q401_R1.6800.97
50_T404_Y1.6710.97
342_F346_F1.6580.97
46_A419_N1.6510.97
455_V484_A1.6460.97
41_G49_Q1.6430.97
357_V361_K1.6400.97
39_V43_E1.6330.96
324_V386_D1.6270.96
270_E311_A1.6190.96
63_V403_L1.6100.96
448_M481_A1.6060.96
483_V511_V1.6000.96
273_I311_A1.5960.96
175_V234_I1.5960.96
225_V254_V1.5890.96
173_L193_L1.5870.96
141_T261_H1.5800.96
286_H299_I1.5720.96
173_L186_L1.5700.96
375_V385_Y1.5680.95
464_T550_T1.5610.95
641_R657_I1.5560.95
79_H356_T1.5370.95
38_L403_L1.5300.95
399_T402_T1.5270.95
434_D588_R1.5230.95
478_L513_V1.5220.95
585_R593_D1.5210.95
283_R287_F1.5170.95
509_Y512_L1.5090.94
349_V403_L1.5030.94
176_E179_Q1.5030.94
99_A147_R1.5010.94
460_R507_G1.4910.94
339_L348_T1.4870.94
202_F224_P1.4850.94
292_D295_A1.4720.94
37_E419_N1.4640.93
269_M310_M1.4580.93
39_V70_L1.4560.93
454_R458_D1.4520.93
372_D385_Y1.4460.93
72_Q148_D1.4430.93
528_S559_N1.4400.93
66_V349_V1.4360.93
20_R68_E1.4280.93
294_V299_I1.4270.93
631_A661_M1.4180.92
455_V483_V1.3970.92
63_V405_V1.3940.92
634_L637_D1.3880.92
441_T567_D1.3840.91
196_D206_T1.3840.91
551_M564_L1.3790.91
189_K192_D1.3770.91
76_V153_V1.3680.91
281_H285_R1.3660.91
266_D270_E1.3640.91
364_Y391_T1.3550.91
187_L191_V1.3520.90
577_I581_Q1.3440.90
639_E643_E1.3410.90
72_Q349_V1.3380.90
139_S143_S1.3300.90
284_V288_E1.3260.90
72_Q345_D1.3150.89
39_V66_V1.3140.89
187_L209_V1.3120.89
484_A508_E1.3070.89
296_A300_E1.3050.89
95_F151_I1.2990.89
175_V186_L1.2920.88
411_D415_A1.2880.88
453_E457_R1.2810.88
636_E639_E1.2770.88
284_V287_F1.2770.88
228_E236_R1.2750.88
589_A592_E1.2680.87
282_E286_H1.2670.87
450_R563_V1.2570.87
414_R420_V1.2540.87
181_I186_L1.2500.87
93_S606_G1.2470.86
350_I402_T1.2460.86
564_L577_I1.2430.86
637_D641_R1.2430.86
228_E238_A1.2430.86
348_T399_T1.2380.86
43_E70_L1.2350.86
424_I586_I1.2350.86
362_G391_T1.2270.85
357_V392_F1.2210.85
463_V533_L1.2170.85
635_V661_M1.2020.84
437_I577_I1.1890.84
274_E278_T1.1850.83
506_L605_V1.1820.83
144_L150_V1.1810.83
239_K249_S1.1800.83
538_Q570_T1.1750.83
324_V331_V1.1670.82
70_L74_T1.1670.82
462_L524_I1.1650.82
167_N268_E1.1620.82
373_S385_Y1.1610.82
199_D210_R1.1610.82
37_E421_V1.1570.82
627_D630_E1.1570.82
414_R417_S1.1540.82
209_V214_V1.1520.82
271_Q275_R1.1480.81
46_A418_A1.1460.81
279_D282_E1.1440.81
76_V151_I1.1430.81
569_T574_Q1.1420.81
177_R252_P1.1410.81
139_S152_V1.1330.81
278_T281_H1.1300.80
325_Y383_T1.1300.80
498_H608_M1.1280.80
79_H545_T1.1210.80
277_R307_L1.1200.80
578_D581_Q1.1190.80
435_I551_M1.1180.80
146_T257_H1.1120.79
339_L395_F1.1090.79
134_D204_Q1.1080.79
50_T416_Q1.1080.79
175_V227_V1.1030.79
119_T317_S1.1000.79
202_F217_Y1.0990.78
132_E136_L1.0970.78
449_D452_D1.0930.78
72_Q347_L1.0930.78
327_S336_Y1.0910.78
63_V66_V1.0880.78
33_D586_I1.0850.78
484_A507_G1.0810.77
412_H416_Q1.0780.77
557_N600_T1.0750.77
67_V76_V1.0720.77
230_W235_D1.0720.77
569_T573_M1.0710.77
167_N170_E1.0680.76
357_V360_I1.0650.76
569_T577_I1.0580.76
360_I399_T1.0550.76
434_D581_Q1.0550.76
453_E561_E1.0520.75
417_S420_V1.0520.75
138_H168_Y1.0500.75
592_E595_G1.0480.75
26_D65_W1.0470.75
361_K411_D1.0440.75
88_Y92_R1.0430.75
224_P242_P1.0370.74
277_R281_H1.0370.74
72_Q400_D1.0350.74
176_E253_A1.0350.74
203_T206_T1.0270.74
269_M326_L1.0260.73
77_I348_T1.0250.73
275_R328_D1.0210.73
503_G509_Y1.0180.73
410_G417_S1.0170.73
448_M478_L1.0170.73
551_M580_T1.0160.73
77_I350_I1.0140.73
275_R278_T1.0140.73
115_Y120_D1.0100.72
435_I564_L1.0080.72
458_D461_V1.0040.72
171_M265_P1.0010.72
65_W69_E1.0010.72
286_H289_R1.0010.72
486_E503_G0.9970.71
439_D567_D0.9960.71
175_V237_M0.9950.71
644_D647_S0.9940.71
532_I564_L0.9940.71
437_I573_M0.9900.71
278_T282_E0.9890.71
279_D326_L0.9880.71
78_A87_L0.9880.71
42_Y401_R0.9880.71
343_P400_D0.9870.71
569_T578_D0.9870.71
656_D660_R0.9800.70
138_H220_Y0.9770.70
431_V558_V0.9770.70
468_K490_D0.9770.70
18_P71_Q0.9750.70
239_K251_E0.9750.70
228_E235_D0.9730.69
365_E391_T0.9720.69
21_V71_Q0.9650.69
268_E271_Q0.9640.69
488_M492_T0.9580.68
79_H355_R0.9570.68
181_I234_I0.9560.68
284_V296_A0.9560.68
288_E296_A0.9540.68
632_A636_E0.9530.68
645_A653_L0.9530.68
41_G419_N0.9490.67
140_A152_V0.9480.67
505_R526_E0.9460.67
606_G609_N0.9420.67
478_L481_A0.9420.67
294_V301_E0.9410.67
451_I463_V0.9400.67
274_E277_R0.9390.67
124_E301_E0.9390.67
454_R461_V0.9370.66
229_F234_I0.9360.66
63_V76_V0.9360.66
41_G403_L0.9350.66
437_I566_A0.9310.66
290_T376_D0.9300.66
148_D401_R0.9270.66
41_G70_L0.9250.65
499_E502_R0.9210.65
182_G188_A0.9140.65
435_I576_A0.9140.65
662_R665_R0.9100.64
492_T500_L0.9060.64
134_D140_A0.9060.64
272_A276_I0.9050.64
164_D327_S0.8960.63
42_Y347_L0.8950.63
455_V511_V0.8940.63
288_E291_G0.8930.63
37_E40_A0.8880.62
285_R288_E0.8870.62
410_G545_T0.8860.62
638_L657_I0.8850.62
339_L346_F0.8810.62
230_W233_E0.8780.61
78_A138_H0.8770.61
323_S367_D0.8750.61
74_T400_D0.8740.61
626_S630_E0.8690.61
468_K491_E0.8670.60
177_R250_E0.8660.60
448_M452_D0.8650.60
348_T400_D0.8650.60
142_R146_T0.8620.60
171_M263_S0.8600.60
271_Q325_Y0.8590.60
223_Y239_K0.8570.60
362_G365_E0.8540.59
152_V341_Y0.8540.59
260_E315_Y0.8510.59
396_A404_Y0.8480.59
77_I356_T0.8460.59
639_E661_M0.8450.58
447_L533_L0.8430.58
68_E97_D0.8430.58
440_A444_V0.8410.58
369_S373_S0.8370.58
186_L227_V0.8350.58
212_D231_G0.8350.58
162_L315_Y0.8340.57
223_Y248_E0.8320.57
465_T533_L0.8310.57
392_F412_H0.8300.57
142_R220_Y0.8280.57
79_H357_V0.8270.57
272_A325_Y0.8230.56
49_Q70_L0.8210.56
361_K365_E0.8210.56
451_I511_V0.8180.56
564_L576_A0.8150.56
50_T396_A0.8150.56
469_R473_D0.8110.55
42_Y72_Q0.8110.55
181_I189_K0.8090.55
404_Y416_Q0.8080.55
471_A484_A0.8080.55
93_S603_K0.8070.55
127_A287_F0.8070.55
451_I461_V0.8060.55
350_I360_I0.8050.55
178_G233_E0.8030.55
662_R666_E0.8010.54
581_Q588_R0.8000.54
655_A659_D0.8000.54
530_V550_T0.8000.54
203_T469_R0.8000.54
175_V256_F0.7980.54
461_V464_T0.7980.54
225_V256_F0.7970.54
152_V597_T0.7960.54
431_V436_S0.7960.54
134_D152_V0.7930.54
25_F603_K0.7930.54
548_V576_A0.7920.54
217_Y224_P0.7910.53
477_Y481_A0.7900.53
307_L311_A0.7900.53
284_V294_V0.7900.53
283_R382_P0.7860.53
231_G235_D0.7860.53
495_L498_H0.7850.53
38_L49_Q0.7850.53
168_Y337_T0.7840.53
452_D456_A0.7840.53
77_I402_T0.7830.53
479_E485_V0.7820.53
438_A563_V0.7810.52
528_S560_G0.7800.52
273_I310_M0.7800.52
101_E143_S0.7800.52
26_D61_N0.7790.52
551_M562_V0.7770.52
77_I395_F0.7770.52
450_R561_E0.7750.52
143_S491_E0.7740.52
634_L660_R0.7720.52
91_F349_V0.7720.52
183_R214_V0.7710.52
214_V237_M0.7690.51
425_V442_G0.7660.51
183_R187_L0.7660.51
247_V250_E0.7650.51
216_V256_F0.7610.51
225_V239_K0.7610.51
493_D496_E0.7610.51
437_I574_Q0.7600.51
78_A260_E0.7590.50
127_A315_Y0.7590.50
459_E560_G0.7580.50
164_D268_E0.7560.50
283_R376_D0.7560.50
174_R253_A0.7550.50
285_R589_A0.7550.50
77_I158_A0.7520.50
592_E599_T0.7510.50
164_D263_S0.7510.50
486_E512_L0.7500.50
25_F65_W0.7490.49
362_G411_D0.7490.49
360_I402_T0.7490.49
50_T418_A0.7490.49
524_I558_V0.7460.49
451_I458_D0.7460.49
126_D317_S0.7450.49
89_E92_R0.7450.49
528_S561_E0.7430.49
183_R209_V0.7430.49
148_D400_D0.7430.49
357_V402_T0.7420.49
597_T604_A0.7410.49
429_H596_T0.7410.49
138_H261_H0.7380.48
451_I455_V0.7370.48
158_A339_L0.7360.48
582_R603_K0.7340.48
26_D68_E0.7330.48
438_A561_E0.7310.48
21_V26_D0.7300.48
136_L496_E0.7300.48
502_R607_D0.7260.47
259_A342_F0.7260.47
72_Q343_P0.7250.47
88_Y138_H0.7240.47
281_H300_E0.7230.47
475_T485_V0.7230.47
138_H260_E0.7220.47
24_P411_D0.7200.47
286_H292_D0.7200.47
576_A582_R0.7180.47
284_V325_Y0.7180.47
287_F290_T0.7170.47
464_T522_L0.7160.46
609_N612_G0.7150.46
145_L341_Y0.7150.46
50_T414_R0.7140.46
611_P614_E0.7130.46
264_V445_E0.7130.46
138_H145_L0.7110.46
625_P628_E0.7100.46
225_V237_M0.7100.46
558_V599_T0.7100.46
302_R375_V0.7100.46
36_A589_A0.7090.46
348_T360_I0.7090.46
612_G615_T0.7030.45
544_E571_D0.7030.45
329_R460_R0.7030.45
190_L227_V0.7020.45
334_A337_T0.7020.45
287_F292_D0.7010.45
362_G410_G0.7010.45
303_T307_L0.7010.45
152_V253_A0.7000.45
253_A444_V0.7000.45
485_V513_V0.6980.45
136_L255_L0.6980.45
208_R215_E0.6970.45
138_H219_M0.6960.45
79_H145_L0.6940.44
237_M251_E0.6940.44
524_I557_N0.6930.44
38_L62_T0.6930.44
24_P602_E0.6920.44
133_I312_E0.6910.44
458_D602_E0.6900.44
163_G261_H0.6900.44
393_A396_A0.6890.44
69_E74_T0.6890.44
39_V42_Y0.6890.44
173_L189_K0.6880.44
75_L158_A0.6880.44
522_L550_T0.6880.44
24_P604_A0.6870.44
438_A565_Y0.6870.44
40_A43_E0.6860.44
251_E254_V0.6860.44
141_T163_G0.6860.44
430_L515_I0.6850.44
242_P469_R0.6850.44
446_D450_R0.6840.43
663_E666_E0.6810.43
458_D595_G0.6800.43
270_E274_E0.6790.43
365_E393_A0.6790.43
292_D299_I0.6770.43
241_D246_T0.6760.43
138_H142_R0.6760.43
191_V207_F0.6760.43
162_L165_P0.6750.43
99_A150_V0.6740.43
134_D138_H0.6740.43
460_R484_A0.6740.43
220_Y240_L0.6740.43
375_V384_A0.6730.42
89_E608_M0.6730.42
451_I483_V0.6730.42
173_L214_V0.6720.42
357_V412_H0.6710.42
488_M501_V0.6710.42
134_D586_I0.6710.42
221_G239_K0.6700.42
75_L339_L0.6700.42
603_K606_G0.6700.42
162_L261_H0.6690.42
109_Y124_E0.6680.42
576_A579_E0.6670.42
25_F118_Q0.6670.42
291_G297_Q0.6650.42
91_F153_V0.6630.42
66_V117_E0.6620.41
79_H87_L0.6620.41
260_E263_S0.6620.41
76_V349_V0.6610.41
585_R592_E0.6600.41
117_E377_N0.6600.41
249_S611_P0.6600.41
463_V595_G0.6590.41
645_A650_E0.6580.41
653_L657_I0.6550.41
334_A390_L0.6550.41
269_M273_I0.6550.41
25_F79_H0.6550.41
275_R331_V0.6550.41
99_A143_S0.6540.41
111_Q126_D0.6530.41
52_L66_V0.6500.40
545_T575_A0.6500.40
246_T442_G0.6500.40
134_D142_R0.6480.40
463_V531_A0.6480.40
148_D343_P0.6460.40
71_Q74_T0.6460.40
344_D400_D0.6450.40
239_K254_V0.6450.40
77_I238_A0.6440.40
455_V461_V0.6430.40
465_T471_A0.6430.40
264_V269_M0.6430.40
568_E571_D0.6430.40
198_N297_Q0.6430.40
73_P343_P0.6430.40
642_M646_A0.6430.40
257_H341_Y0.6420.40
362_G495_L0.6410.40
107_Y157_S0.6410.40
287_F331_V0.6410.40
631_A634_L0.6400.39
435_I573_M0.6390.39
23_A26_D0.6380.39
268_E328_D0.6380.39
21_V39_V0.6370.39
340_D398_K0.6370.39
181_I229_F0.6370.39
301_E317_S0.6360.39
422_E582_R0.6360.39
21_V61_N0.6350.39
582_R586_I0.6340.39
215_E240_L0.6340.39
218_P341_Y0.6340.39
91_F346_F0.6320.39
292_D376_D0.6320.39
503_G506_L0.6320.39
362_G572_A0.6320.39
262_Y425_V0.6310.39
492_T496_E0.6310.39
364_Y372_D0.6310.39
281_H304_T0.6310.39
613_A616_D0.6300.39
29_G32_P0.6290.38
529_L563_V0.6290.38
579_E603_K0.6290.38
280_M287_F0.6290.38
502_R605_V0.6290.38
444_V478_L0.6280.38
188_A192_D0.6270.38
185_Q189_K0.6270.38
373_S491_E0.6260.38
28_A122_Y0.6260.38
133_I356_T0.6250.38
431_V434_D0.6250.38
77_I357_V0.6240.38
141_T162_L0.6230.38
107_Y141_T0.6230.38
116_V607_D0.6210.38
127_A385_Y0.6200.38
92_R662_R0.6200.38
339_L342_F0.6190.38
237_M256_F0.6190.38
640_A644_D0.6180.37
63_V91_F0.6180.37
455_V509_Y0.6180.37
468_K509_Y0.6180.37
54_V63_V0.6180.37
43_E46_A0.6180.37
262_Y485_V0.6160.37
488_M494_T0.6160.37
633_L640_A0.6160.37
142_R172_S0.6160.37
63_V151_I0.6150.37
339_L390_L0.6140.37
471_A488_M0.6130.37
24_P65_W0.6130.37
471_A509_Y0.6110.37
238_A250_E0.6110.37
462_L522_L0.6110.37
486_E492_T0.6110.37
641_R645_A0.6110.37
47_Q399_T0.6100.37
88_Y524_I0.6100.37
458_D528_S0.6090.37
85_A493_D0.6090.37
114_A326_L0.6080.37
491_E512_L0.6080.37
79_H144_L0.6080.37
77_I154_A0.6070.37
454_R457_R0.6060.36
280_M299_I0.6060.36
208_R245_G0.6050.36
572_A651_F0.6050.36
350_I412_H0.6040.36
106_Y157_S0.6030.36
476_E479_E0.6030.36
145_L152_V0.6020.36
597_T600_T0.6020.36
62_T423_Q0.6010.36
260_E515_I0.6010.36
89_E502_R0.6000.36
186_L189_K0.5990.36
157_S163_G0.5990.36
373_S391_T0.5980.36
33_D421_V0.5980.36
64_S85_A0.5980.36
502_R515_I0.5970.36
44_Q47_Q0.5970.36
121_K133_I0.5970.36
162_L169_E0.5960.36
357_V530_V0.5960.36
135_R193_L0.5960.36
410_G414_R0.5950.35
43_E74_T0.5950.35
327_S333_D0.5950.35
127_A293_M0.5950.35
572_A575_A0.5940.35
650_E665_R0.5940.35
235_D592_E0.5940.35
166_R170_E0.5930.35
434_D559_N0.5930.35
198_N243_L0.5930.35
628_E632_A0.5930.35
91_F151_I0.5910.35
33_D424_I0.5900.35
601_I604_A0.5900.35
77_I143_S0.5890.35
310_M319_I0.5880.35
78_A545_T0.5880.35
251_E611_P0.5870.35
457_R528_S0.5870.35
79_H132_E0.5860.35
287_F297_Q0.5860.35
107_Y129_I0.5860.35
145_L495_L0.5840.35
470_M474_L0.5840.35
36_A43_E0.5840.35
57_S63_V0.5830.34
395_F527_V0.5830.34
303_T325_Y0.5830.34
455_V510_D0.5830.34
280_M304_T0.5820.34
161_G343_P0.5810.34
63_V70_L0.5810.34
166_R172_S0.5810.34
145_L287_F0.5810.34
630_E633_L0.5810.34
116_V219_M0.5810.34
74_T79_H0.5800.34
337_T609_N0.5800.34
135_R545_T0.5800.34
193_L263_S0.5800.34
21_V69_E0.5790.34
89_E606_G0.5790.34
500_L509_Y0.5790.34
626_S634_L0.5790.34
25_F76_V0.5780.34
264_V326_L0.5780.34
545_T600_T0.5780.34
19_F74_T0.5760.34
461_V550_T0.5750.34
163_G309_M0.5740.34
491_E513_V0.5740.34
155_S391_T0.5730.34
65_W71_Q0.5730.34
390_L398_K0.5730.34
48_Q143_S0.5720.34
373_S377_N0.5720.34
345_D400_D0.5720.34
25_F94_L0.5720.34
122_Y661_M0.5720.34
548_V551_M0.5720.34
140_A261_H0.5710.33
18_P68_E0.5700.33
364_Y369_S0.5700.33
255_L264_V0.5700.33
448_M513_V0.5690.33
185_Q188_A0.5690.33
442_G449_D0.5690.33
75_L342_F0.5680.33
165_P384_A0.5680.33
279_D283_R0.5670.33
244_E478_L0.5670.33
579_E583_R0.5650.33
154_A168_Y0.5650.33
227_V256_F0.5650.33
616_D619_D0.5640.33
262_Y315_Y0.5640.33
395_F404_Y0.5630.33
461_V512_L0.5620.33
631_A664_L0.5620.33
395_F465_T0.5620.33
644_D650_E0.5610.33
87_L91_F0.5610.33
230_W470_M0.5610.33
633_L638_L0.5610.33
174_R255_L0.5600.33
179_Q234_I0.5590.32
431_V575_A0.5590.32
99_A164_D0.5590.32
33_D411_D0.5580.32
132_E501_V0.5570.32
638_L652_E0.5570.32
317_S373_S0.5570.32
524_I564_L0.5570.32
237_M557_N0.5560.32
154_A225_V0.5560.32
60_T63_V0.5550.32
291_G294_V0.5540.32
399_T404_Y0.5540.32
172_S255_L0.5540.32
132_E524_I0.5530.32
94_L138_H0.5530.32
243_L369_S0.5530.32
586_I589_A0.5530.32
157_S309_M0.5520.32
43_E72_Q0.5520.32
120_D301_E0.5510.32
89_E609_N0.5510.32
425_V432_D0.5510.32
440_A567_D0.5500.32
50_T164_D0.5500.32
212_D230_W0.5480.32
452_D483_V0.5470.31
268_E275_R0.5470.31
76_V469_R0.5460.31
124_E129_I0.5460.31
585_R588_R0.5460.31
431_V576_A0.5450.31
28_A421_V0.5450.31
131_D204_Q0.5450.31
350_I618_A0.5450.31
645_A648_N0.5440.31
122_Y373_S0.5440.31
403_L597_T0.5430.31
171_M228_E0.5430.31
204_Q260_E0.5430.31
524_I527_V0.5430.31
72_Q341_Y0.5420.31
330_E334_A0.5410.31
357_V524_I0.5410.31
259_A317_S0.5410.31
28_A32_P0.5410.31
275_R310_M0.5410.31
41_G301_E0.5400.31
74_T150_V0.5390.31
395_F399_T0.5390.31
167_N327_S0.5390.31
175_V193_L0.5380.31
337_T398_K0.5380.31
79_H411_D0.5380.31
150_V481_A0.5380.31
162_L167_N0.5370.31
661_M665_R0.5370.31
416_Q513_V0.5370.31
471_A492_T0.5370.31
641_R644_D0.5360.31
537_Q550_T0.5360.31
70_L403_L0.5360.31
116_V377_N0.5360.31
168_Y261_H0.5360.31
142_R169_E0.5350.31
99_A106_Y0.5350.31
164_D377_N0.5350.31
22_E71_Q0.5350.31
355_R358_P0.5350.31
455_V513_V0.5340.30
451_I454_R0.5340.30
57_S365_E0.5340.30
447_L529_L0.5330.30
163_G462_L0.5330.30
650_E661_M0.5320.30
122_Y299_I0.5320.30
116_V310_M0.5310.30
414_R545_T0.5310.30
271_Q328_D0.5310.30
236_R515_I0.5310.30
48_Q396_A0.5300.30
140_A368_K0.5300.30
610_L613_A0.5300.30
43_E592_E0.5290.30
349_V524_I0.5290.30
217_Y221_G0.5280.30
21_V95_F0.5280.30
158_A259_A0.5270.30
213_T228_E0.5270.30
310_M313_A0.5270.30
118_Q545_T0.5260.30
337_T543_S0.5260.30
217_Y494_T0.5260.30
373_S376_D0.5250.30
225_V395_F0.5240.30
85_A498_H0.5240.30
337_T473_D0.5240.30
585_R665_R0.5240.30
102_Y347_L0.5240.30
78_A491_E0.5230.30
195_Y530_V0.5230.30
303_T383_T0.5230.30
107_Y142_R0.5230.30
91_F132_E0.5220.29
220_Y257_H0.5220.29
177_R180_S0.5220.29
206_T245_G0.5220.29
48_Q402_T0.5220.29
227_V630_E0.5210.29
68_E246_T0.5210.29
138_H141_T0.5210.29
219_M242_P0.5210.29
221_G225_V0.5200.29
462_L543_S0.5200.29
375_V527_V0.5200.29
403_L508_E0.5200.29
449_D453_E0.5200.29
573_M579_E0.5200.29
657_I661_M0.5200.29
310_M445_E0.5190.29
479_E486_E0.5180.29
28_A599_T0.5180.29
479_E499_E0.5180.29
484_A509_Y0.5170.29
615_T621_A0.5170.29
161_G337_T0.5170.29
616_D621_A0.5160.29
568_E574_Q0.5160.29
163_G197_R0.5160.29
221_G488_M0.5160.29
585_R597_T0.5160.29
449_D481_A0.5150.29
515_I524_I0.5150.29
447_L451_I0.5150.29
78_A262_Y0.5150.29
39_V68_E0.5150.29
30_D34_A0.5140.29
162_L548_V0.5140.29
252_P262_Y0.5140.29
288_E299_I0.5140.29
346_F400_D0.5130.29
310_M499_E0.5130.29
124_E300_E0.5130.29
127_A326_L0.5130.29
106_Y109_Y0.5130.29
634_L641_R0.5120.29
169_E172_S0.5120.29
140_A204_Q0.5120.29
392_F418_A0.5110.29
265_P326_L0.5110.29
97_D457_R0.5110.29
21_V97_D0.5110.29
155_S608_M0.5110.29
70_L349_V0.5110.29
134_D503_G0.5100.29
461_V522_L0.5100.29
175_V181_I0.5100.29
37_E69_E0.5090.28
362_G397_D0.5090.28
265_P327_S0.5080.28
116_V385_Y0.5070.28
134_D155_S0.5070.28
377_N648_N0.5070.28
33_D644_D0.5070.28
122_Y590_F0.5060.28
238_A249_S0.5060.28
134_D158_A0.5060.28
262_Y334_A0.5050.28
202_F208_R0.5040.28
282_E325_Y0.5040.28
140_A265_P0.5040.28
538_Q571_D0.5030.28
376_D575_A0.5030.28
361_K393_A0.5030.28
138_H498_H0.5030.28
313_A404_Y0.5030.28
220_Y342_F0.5030.28
297_Q301_E0.5030.28
176_E220_Y0.5020.28
109_Y157_S0.5020.28
88_Y171_M0.5020.28
170_E593_D0.5020.28
340_D395_F0.5020.28
299_I414_R0.5020.28
46_A421_V0.5020.28
66_V421_V0.5010.28
504_L507_G0.5010.28
307_L325_Y0.5010.28
138_H184_D0.5000.28
425_V551_M0.5000.28
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2d7dA 2 0.9071 100 0.502 Contact Map
1c4oA 1 0.717 100 0.508 Contact Map
2eyqA 1 0.807 100 0.733 Contact Map
3hjhA 1 0.6241 100 0.743 Contact Map
4gl2A 1 0.7199 100 0.887 Contact Map
4a4zA 1 0.6226 100 0.894 Contact Map
4nl4H 1 0.5951 100 0.903 Contact Map
1gm5A 1 0.5472 100 0.904 Contact Map
2ocaA 1 0.5225 100 0.906 Contact Map
3fhoA 2 0.418 100 0.906 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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