GREMLIN Database
Q9HMT3 - Sulfate transport system ATP-binding protein
UniProt: Q9HMT3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 343 (268)
Sequences: 19105 (14130)
Seq/√Len: 863.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
8_G22_D4.4381.00
31_E205_R4.1631.00
200_L221_E4.0021.00
18_T21_D3.9631.00
6_L9_L3.6091.00
7_Q60_E3.4341.00
11_R49_L2.9951.00
34_T203_S2.9781.00
218_G222_A2.9321.00
5_E26_S2.8821.00
9_L56_P2.8011.00
10_V58_R2.7801.00
181_I187_I2.6871.00
47_L158_L2.6221.00
47_L192_V2.4541.00
91_M99_Y2.4291.00
219_T222_A2.3631.00
90_H134_A2.3541.00
128_T131_R2.3531.00
33_F207_A2.3391.00
28_A31_E2.3101.00
94_R98_A2.2811.00
21_D213_A2.2361.00
11_R54_E2.1551.00
11_R57_D2.1401.00
10_V22_D2.1241.00
27_I33_F1.9821.00
179_K201_S1.9551.00
48_R53_F1.9411.00
131_R135_A1.9211.00
5_E62_V1.9091.00
222_A226_E1.8861.00
34_T199_A1.8781.00
91_M95_E1.8701.00
10_V18_T1.8481.00
7_Q62_V1.8191.00
6_L25_V1.8161.00
25_V207_A1.8131.00
12_A18_T1.7561.00
8_G24_S1.7541.00
205_R217_V1.7421.00
49_L56_P1.7091.00
77_D155_S1.7021.00
91_M96_N1.6761.00
12_A57_D1.6501.00
92_T95_E1.5841.00
10_V21_D1.5581.00
6_L50_I1.5291.00
270_T274_A1.5291.00
95_E98_A1.5161.00
109_G112_T1.5141.00
175_R201_S1.5101.00
48_R54_E1.4991.00
79_G149_A1.4931.00
274_A278_R1.4861.00
132_E135_A1.4711.00
114_E118_E1.4531.00
20_V23_V1.4081.00
191_Y203_S1.3921.00
220_P224_Y1.3831.00
115_R153_G1.3821.00
111_S115_R1.3601.00
226_E229_S1.3401.00
203_S206_V1.3401.00
268_C271_G1.3371.00
281_A285_G1.3181.00
88_F91_M1.3131.00
96_N148_R1.3031.00
115_R118_E1.2931.00
51_A158_L1.2921.00
208_V227_P1.2851.00
33_F205_R1.2841.00
133_P144_V1.2811.00
123_V147_A1.2661.00
79_G154_P1.2641.00
117_S125_L1.2611.00
276_G280_E1.2571.00
13_F19_A1.2561.00
207_A214_V1.2541.00
279_P282_L1.2531.00
94_R130_D1.2501.00
277_L281_A1.2401.00
208_V223_V1.2191.00
20_V49_L1.2071.00
222_A225_R1.2031.00
264_E267_E1.1981.00
210_R213_A1.1971.00
49_L61_I1.1901.00
193_T199_A1.1791.00
111_S114_E1.1781.00
7_Q24_S1.1781.00
113_E117_S1.1581.00
8_G58_R1.1541.00
53_F82_F1.1501.00
89_P134_A1.1411.00
31_E204_D1.1371.00
153_G187_I1.1341.00
27_I188_T1.1331.00
96_N133_P1.1161.00
277_L280_E1.1121.00
166_L174_L1.1091.00
259_N262_T1.1041.00
255_S258_V1.1031.00
274_A281_A1.1021.00
101_L104_R1.0981.00
98_A116_V1.0981.00
233_A237_G1.0841.00
87_L96_N1.0821.00
38_P41_C1.0811.00
271_G274_A1.0801.00
269_V273_V1.0791.00
121_S126_A1.0701.00
221_E225_R1.0671.00
41_C209_M1.0581.00
260_G264_E1.0571.00
50_I190_V1.0561.00
120_L129_G1.0511.00
234_E238_E1.0481.00
30_G188_T1.0461.00
260_G263_F1.0431.00
281_A284_F1.0401.00
51_A80_I1.0291.00
176_G180_E1.0221.00
259_N264_E1.0191.00
94_R129_G1.0191.00
278_R281_A1.0181.00
210_R215_V1.0161.00
267_E270_T1.0001.00
270_T273_V0.9941.00
254_S258_V0.9931.00
266_S270_T0.9931.00
117_S129_G0.9911.00
182_Q187_I0.9811.00
272_D275_V0.9781.00
90_H132_E0.9671.00
278_R282_L0.9621.00
262_T266_S0.9561.00
64_G155_S0.9491.00
266_S269_V0.9431.00
178_I189_T0.9421.00
271_G275_V0.9411.00
236_V240_N0.9411.00
273_V281_A0.9371.00
117_S121_S0.9341.00
263_F267_E0.9291.00
93_V136_L0.9291.00
176_G179_K0.9231.00
172_D176_G0.9201.00
9_L49_L0.9181.00
251_T254_S0.9171.00
265_V268_C0.9151.00
124_D127_G0.9111.00
267_E271_G0.9111.00
225_R229_S0.9081.00
255_S259_N0.9081.00
171_R195_D0.9061.00
261_V264_E0.9011.00
94_R116_V0.9001.00
81_V149_A0.9001.00
98_A102_R0.8851.00
253_G256_V0.8841.00
273_V277_L0.8811.00
11_R45_T0.8781.00
274_A280_E0.8771.00
119_L147_A0.8771.00
274_A277_L0.8761.00
235_F238_E0.8751.00
237_G240_N0.8741.00
56_P61_I0.8611.00
276_G279_P0.8581.00
100_G148_R0.8501.00
191_Y202_I0.8451.00
281_A287_G0.8451.00
197_A201_S0.8441.00
28_A205_R0.8401.00
262_T265_V0.8391.00
35_L46_T0.8391.00
136_L144_V0.8361.00
92_T96_N0.8351.00
245_T248_P0.8341.00
77_D152_P0.8301.00
63_F76_R0.8281.00
270_T278_R0.8281.00
280_E284_F0.8261.00
52_G55_T0.8261.00
6_L61_I0.8261.00
273_V276_G0.8201.00
284_F287_G0.8191.00
33_F190_V0.8181.00
257_S260_G0.8171.00
275_V279_P0.8161.00
118_E121_S0.8121.00
258_V263_F0.8121.00
279_P283_S0.8101.00
239_N243_S0.8091.00
99_Y103_F0.8041.00
275_V278_R0.8031.00
269_V272_D0.8001.00
29_D155_S0.7991.00
101_L105_E0.7911.00
282_L286_S0.7891.00
96_N99_Y0.7861.00
107_P110_A0.7841.00
156_V188_T0.7801.00
44_T48_R0.7791.00
32_F189_T0.7781.00
207_A217_V0.7771.00
256_V259_N0.7761.00
259_N263_F0.7741.00
223_V227_P0.7741.00
268_C273_V0.7741.00
12_A15_S0.7731.00
205_R215_V0.7721.00
260_G267_E0.7691.00
238_E242_V0.7691.00
258_V262_T0.7681.00
94_R97_V0.7661.00
240_N244_G0.7651.00
248_P252_G0.7641.00
32_F191_Y0.7631.00
263_F268_C0.7611.00
16_T19_A0.7601.00
272_D276_G0.7601.00
264_E268_C0.7601.00
239_N242_V0.7591.00
100_G103_F0.7581.00
269_V274_A0.7581.00
280_E283_S0.7561.00
64_G76_R0.7551.00
110_A114_E0.7511.00
232_V236_V0.7511.00
252_G255_S0.7511.00
260_G265_V0.7511.00
94_R117_S0.7491.00
263_F266_S0.7491.00
49_L57_D0.7461.00
22_D213_A0.7441.00
283_S287_G0.7441.00
224_Y228_S0.7411.00
49_L54_E0.7401.00
93_V96_N0.7341.00
129_G132_E0.7331.00
210_R214_V0.7331.00
97_V100_G0.7311.00
256_V260_G0.7311.00
262_T267_E0.7271.00
80_I83_Q0.7261.00
4_V156_V0.7261.00
119_L122_L0.7251.00
270_T275_V0.7231.00
118_E122_L0.7211.00
54_E57_D0.7201.00
243_S246_A0.7191.00
158_L190_V0.7181.00
79_G83_Q0.7161.00
219_T223_V0.7121.00
20_V46_T0.7121.00
280_E287_G0.7111.00
120_L125_L0.7091.00
12_A16_T0.7031.00
64_G75_D0.6951.00
13_F45_T0.6931.00
256_V261_V0.6861.00
234_E237_G0.6851.00
9_L61_I0.6841.00
250_E254_S0.6811.00
236_V239_N0.6801.00
269_V276_G0.6781.00
112_T116_V0.6771.00
232_V235_F0.6721.00
224_Y227_P0.6721.00
126_A129_G0.6701.00
182_Q189_T0.6701.00
22_D58_R0.6691.00
282_L285_G0.6661.00
277_L282_L0.6661.00
159_L189_T0.6661.00
146_L159_L0.6641.00
275_V281_A0.6631.00
246_A250_E0.6631.00
255_S262_T0.6601.00
81_V142_Q0.6591.00
256_V263_F0.6511.00
177_T180_E0.6491.00
35_L209_M0.6461.00
263_F270_T0.6441.00
254_S257_S0.6431.00
15_S18_T0.6421.00
275_V280_E0.6391.00
258_V261_V0.6381.00
251_T255_S0.6381.00
13_F54_E0.6381.00
271_G276_G0.6341.00
221_E224_Y0.6331.00
257_S262_T0.6311.00
133_P141_Q0.6291.00
6_L46_T0.6281.00
124_D173_R0.6281.00
11_R20_V0.6281.00
216_Q226_E0.6271.00
267_E274_A0.6261.00
12_A58_R0.6231.00
227_P232_V0.6231.00
119_L151_A0.6221.00
220_P223_V0.6211.00
98_A103_F0.6211.00
21_D212_G0.6201.00
25_V46_T0.6181.00
241_V244_G0.6171.00
275_V285_G0.6171.00
244_G247_V0.6161.00
264_E269_V0.6161.00
248_P251_T0.6141.00
46_T209_M0.6101.00
109_G113_E0.6071.00
270_T280_E0.6071.00
251_T256_V0.6071.00
273_V280_E0.6061.00
238_E241_V0.6061.00
282_L287_G0.6061.00
27_I156_V0.6051.00
23_V214_V0.6041.00
199_A203_S0.6041.00
107_P111_S0.6031.00
179_K202_I0.6021.00
233_A236_V0.6001.00
12_A19_A0.5991.00
7_Q26_S0.5981.00
78_V156_V0.5941.00
242_V245_T0.5911.00
206_V220_P0.5901.00
93_V144_V0.5871.00
99_Y102_R0.5851.00
229_S234_E0.5851.00
52_G63_F0.5841.00
261_V267_E0.5811.00
225_R228_S0.5791.00
235_F239_N0.5781.00
255_S260_G0.5781.00
245_T249_L0.5771.00
269_V275_V0.5771.00
253_G257_S0.5771.00
168_A172_D0.5761.00
96_N100_G0.5761.00
192_V195_D0.5751.00
23_V46_T0.5721.00
10_V20_V0.5701.00
181_I189_T0.5661.00
280_E285_G0.5661.00
257_S270_T0.5661.00
249_L252_G0.5651.00
216_Q223_V0.5641.00
110_A113_E0.5631.00
4_V63_F0.5631.00
276_G281_A0.5601.00
200_L219_T0.5581.00
271_G277_L0.5541.00
47_L51_A0.5541.00
237_G241_V0.5541.00
155_S187_I0.5521.00
92_T132_E0.5501.00
97_V101_L0.5491.00
266_S275_V0.5421.00
262_T268_C0.5421.00
264_E270_T0.5411.00
154_P181_I0.5411.00
231_F235_F0.5401.00
14_G18_T0.5391.00
252_G256_V0.5361.00
257_S263_F0.5351.00
270_T281_A0.5331.00
268_C276_G0.5331.00
175_R198_E0.5321.00
274_A285_G0.5291.00
279_P284_F0.5291.00
270_T276_G0.5291.00
106_P110_A0.5281.00
29_D64_G0.5261.00
275_V282_L0.5251.00
267_E272_D0.5251.00
191_Y199_A0.5251.00
266_S271_G0.5241.00
259_N265_V0.5241.00
256_V262_T0.5221.00
277_L284_F0.5211.00
240_N243_S0.5201.00
259_N267_E0.5201.00
254_S261_V0.5191.00
261_V268_C0.5181.00
274_A283_S0.5181.00
209_M214_V0.5161.00
97_V151_A0.5151.00
283_S286_S0.5131.00
278_R285_G0.5131.00
270_T279_P0.5121.00
36_V208_V0.5101.00
257_S261_V0.5091.00
50_I158_L0.5081.00
272_D279_P0.5051.00
270_T277_L0.5051.00
261_V265_V0.5041.00
87_L133_P0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2yyzA 1 0.9708 100 0.247 Contact Map
1v43A 2 0.965 100 0.248 Contact Map
2it1A 1 0.9942 100 0.25 Contact Map
1oxxK 1 0.9796 100 0.252 Contact Map
1g291 4 0.9942 100 0.253 Contact Map
1z47A 2 0.9883 100 0.253 Contact Map
3rlfA 2 0.9913 100 0.257 Contact Map
3tuiC 2 0.965 100 0.259 Contact Map
3fvqA 2 0.965 100 0.263 Contact Map
4yerA 2 0.8192 100 0.268 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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