Q9HMR3 - HALSA - GREMLIN Contacts

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Q9HMR3 - O-acetyl homoserine

UniProt:	Q9HMR3	Sequences: MGHDHGLHTNSVHAGQRVDPATGARAPPLYQTTSYAFEDSADAAGQFALERDGYIYSRLMNPTVETLQDRLAALEGGVGAVATASGMAALDLATFLLARAGDSVVAASDLYGGTVTYLTHSAQRRGVDTTFVDVLDYDAYADAIDADTAYVLVETVGNPSLITPDLERIADIAHDNGVPLLVDNTFATPALATPIDHGADIVWHSTTKWIHGAGTTVGGALVDAGSFDWDAHAADYPEIAQENPAYHGVTFTDRFGDAAFTYAAIARGLRDLGNQQSPFDAWQTLQKLETLPLRMQQHCRNAQLVAEHLRDHPNVSWVNYPGLADHDTHDNATTYLDSGYGGMLTFGVEDGYEAAQSVTEETTLASLLANVGDAKTLVIHPASTTHQQLTPEAQRAGGVRPEMVRVSVGIEDPADIVADLETAIEAAVGSA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	431 (420)
Sequences:	3165 (1426)
Seq/√Len:	69.6

ECOLI - METB METC
BACSU - METC MCCB METI
HALSA - Q9HMR3 Q9HR98 Q9HQG7
SULSO - Q97W69

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
310_R	325_D	3.865	1.00
141_A	175_D	3.783	1.00
65_E	69_D	3.617	1.00
103_S	145_D	3.467	1.00
8_H	412_D	3.437	1.00
193_T	196_D	3.432	1.00
45_G	50_E	3.129	1.00
317_W	347_G	3.123	1.00
103_S	130_T	2.928	1.00
41_A	45_G	2.925	1.00
303_Q	307_E	2.853	1.00
195_I	224_A	2.824	1.00
365_A	376_T	2.744	1.00
186_F	371_V	2.700	1.00
174_H	200_D	2.618	1.00
210_I	288_L	2.508	1.00
347_G	402_E	2.450	1.00
221_L	264_A	2.438	1.00
329_H	333_T	2.434	1.00
305_V	416_I	2.422	1.00
421_E	425_E	2.413	1.00
10_N	73_A	2.410	1.00
308_H	421_E	2.381	1.00
141_A	176_N	2.373	1.00
167_E	171_D	2.325	1.00
307_E	324_A	2.259	1.00
216_T	280_D	2.239	1.00
102_D	149_A	2.189	1.00
45_G	51_R	2.182	1.00
71_L	220_A	2.179	1.00
64_V	281_A	2.146	1.00
130_T	145_D	2.139	1.00
79_G	261_T	2.096	1.00
54_Y	60_M	2.075	1.00
394_Q	401_P	2.061	1.00
144_I	151_V	2.043	1.00
71_L	222_V	2.037	1.00
14_A	73_A	1.984	1.00
167_E	334_T	1.983	1.00
276_Q	281_A	1.978	1.00
296_Q	300_R	1.963	1.00
92_L	274_N	1.941	1.00
231_A	234_A	1.938	1.00
167_E	335_Y	1.925	1.00
413_P	417_V	1.920	1.00
317_W	402_E	1.915	1.00
136_D	139_A	1.914	1.00
228_D	231_A	1.896	1.00
67_L	220_A	1.893	1.00
11_S	292_P	1.887	1.00
150_Y	181_L	1.886	1.00
6_G	412_D	1.880	1.00
153_V	164_P	1.857	1.00
316_S	349_E	1.855	1.00
23_G	38_E	1.844	1.00
365_A	420_L	1.843	1.00
94_T	150_Y	1.827	1.00
81_V	264_A	1.819	1.00
57_S	64_V	1.813	1.00
316_S	402_E	1.800	1.00
167_E	197_H	1.793	1.00
132_V	143_A	1.790	1.00
81_V	261_T	1.790	1.00
137_Y	168_R	1.780	1.00
7_L	190_A	1.746	1.00
25_R	366_S	1.744	1.00
209_W	342_G	1.719	1.00
10_N	14_A	1.716	1.00
171_D	175_D	1.713	1.00
391_P	401_P	1.684	1.00
138_D	141_A	1.677	1.00
358_V	378_V	1.672	1.00
200_D	226_S	1.667	0.99
362_T	378_V	1.664	0.99
406_V	420_L	1.662	0.99
42_D	51_R	1.655	0.99
128_D	145_D	1.653	0.99
390_T	393_A	1.651	0.99
83_T	92_L	1.637	0.99
64_V	276_Q	1.636	0.99
230_D	252_T	1.601	0.99
93_A	260_F	1.601	0.99
32_T	35_Y	1.597	0.99
279_F	283_Q	1.595	0.99
179_P	236_Y	1.588	0.99
38_E	42_D	1.584	0.99
345_T	403_M	1.583	0.99
135_L	328_T	1.580	0.99
380_H	383_S	1.568	0.99
348_V	358_V	1.560	0.99
153_V	169_I	1.560	0.99
75_E	204_H	1.543	0.99
67_L	284_T	1.540	0.99
153_V	166_L	1.538	0.99
137_Y	172_I	1.511	0.99
164_P	169_I	1.505	0.99
42_D	46_Q	1.500	0.99
305_V	417_V	1.494	0.99
206_T	284_T	1.490	0.99
234_A	241_Q	1.480	0.99
41_A	356_Q	1.473	0.99
374_A	410_I	1.470	0.99
234_A	240_A	1.450	0.99
27_P	285_L	1.447	0.99
351_G	354_A	1.445	0.99
151_V	178_V	1.444	0.99
96_L	264_A	1.433	0.98
263_A	267_R	1.431	0.98
140_Y	151_V	1.417	0.98
161_L	321_P	1.412	0.98
195_I	202_V	1.410	0.98
206_T	220_A	1.404	0.98
67_L	206_T	1.399	0.98
277_S	280_D	1.387	0.98
91_D	95_F	1.385	0.98
103_S	128_D	1.381	0.98
191_L	299_C	1.373	0.98
94_T	118_L	1.358	0.98
181_L	203_W	1.356	0.98
300_R	304_L	1.348	0.98
68_Q	265_I	1.347	0.98
153_V	182_V	1.342	0.98
352_Y	356_Q	1.342	0.98
170_A	180_L	1.337	0.98
357_S	361_E	1.333	0.97
305_V	406_V	1.332	0.97
302_A	306_A	1.332	0.97
67_L	82_A	1.326	0.97
138_D	142_D	1.317	0.97
258_A	262_Y	1.305	0.97
369_A	379_I	1.303	0.97
305_V	420_L	1.297	0.97
103_S	147_D	1.297	0.97
165_D	168_R	1.296	0.97
256_G	259_A	1.293	0.97
319_N	326_H	1.292	0.97
365_A	378_V	1.288	0.97
40_S	360_E	1.285	0.97
6_G	418_A	1.272	0.97
206_T	276_Q	1.264	0.97
391_P	395_R	1.261	0.96
29_L	282_W	1.252	0.96
304_L	307_E	1.249	0.96
93_A	181_L	1.246	0.96
64_V	82_A	1.244	0.96
97_L	181_L	1.244	0.96
92_L	268_G	1.236	0.96
81_V	221_L	1.224	0.96
12_V	410_I	1.219	0.96
25_R	36_A	1.217	0.96
314_N	424_I	1.211	0.96
106_A	118_L	1.210	0.96
166_L	192_A	1.210	0.96
144_I	176_N	1.205	0.95
31_Q	216_T	1.204	0.95
137_Y	140_Y	1.201	0.95
109_D	162_I	1.197	0.95
166_L	180_L	1.193	0.95
19_D	22_T	1.190	0.95
304_L	417_V	1.175	0.95
161_L	344_L	1.174	0.95
169_I	180_L	1.170	0.95
365_A	416_I	1.169	0.95
7_L	292_P	1.160	0.94
326_H	329_H	1.159	0.94
17_R	69_D	1.155	0.94
95_F	125_R	1.154	0.94
6_G	414_A	1.151	0.94
84_A	274_N	1.148	0.94
180_L	199_A	1.147	0.94
99_R	124_R	1.143	0.94
239_I	252_T	1.131	0.94
337_D	340_Y	1.129	0.94
353_E	356_Q	1.127	0.93
144_I	178_V	1.125	0.93
238_E	263_A	1.125	0.93
243_N	267_R	1.122	0.93
130_T	143_A	1.118	0.93
330_D	333_T	1.111	0.93
153_V	180_L	1.110	0.93
250_T	253_D	1.110	0.93
98_A	104_V	1.107	0.93
87_M	90_L	1.107	0.93
135_L	162_I	1.105	0.93
305_V	413_P	1.105	0.93
184_N	187_A	1.096	0.93
308_H	312_H	1.093	0.92
8_H	292_P	1.093	0.92
52_D	262_Y	1.088	0.92
223_D	261_T	1.088	0.92
99_R	238_E	1.080	0.92
157_G	162_I	1.079	0.92
301_N	410_I	1.072	0.92
52_D	258_A	1.061	0.91
364_L	416_I	1.054	0.91
197_H	335_Y	1.053	0.91
333_T	340_Y	1.052	0.91
155_T	184_N	1.045	0.91
96_L	260_F	1.044	0.91
168_R	172_I	1.041	0.90
91_D	272_L	1.038	0.90
303_Q	322_G	1.030	0.90
391_P	394_Q	1.029	0.90
34_S	217_V	1.028	0.90
96_L	268_G	1.025	0.90
71_L	210_I	1.023	0.90
93_A	97_L	1.023	0.90
96_L	263_A	1.020	0.90
156_V	187_A	1.020	0.90
7_L	193_T	1.017	0.89
363_T	422_T	1.005	0.89
240_A	250_T	1.003	0.89
206_T	218_G	1.001	0.89
57_S	276_Q	0.997	0.88
200_D	224_A	0.995	0.88
83_T	221_L	0.993	0.88
226_S	257_D	0.992	0.88
197_H	334_T	0.989	0.88
36_A	366_S	0.989	0.88
216_T	284_T	0.988	0.88
304_L	413_P	0.985	0.88
118_L	129_T	0.982	0.88
348_V	424_I	0.980	0.88
72_A	80_A	0.980	0.88
324_A	329_H	0.977	0.87
78_V	223_D	0.977	0.87
78_V	258_A	0.974	0.87
241_Q	250_T	0.972	0.87
365_A	406_V	0.967	0.87
84_A	275_Q	0.966	0.87
27_P	66_T	0.965	0.87
378_V	404_V	0.959	0.86
105_V	143_A	0.958	0.86
24_A	30_Y	0.956	0.86
78_V	261_T	0.952	0.86
310_R	326_H	0.946	0.86
124_R	267_R	0.943	0.85
376_T	416_I	0.943	0.85
90_L	117_Y	0.942	0.85
71_L	206_T	0.941	0.85
123_Q	128_D	0.937	0.85
39_D	360_E	0.935	0.85
314_N	348_V	0.934	0.85
419_D	422_T	0.933	0.85
170_A	174_H	0.927	0.85
363_T	426_A	0.925	0.84
31_Q	279_F	0.923	0.84
134_V	139_A	0.922	0.84
103_S	146_A	0.922	0.84
347_G	400_R	0.920	0.84
77_G	222_V	0.918	0.84
190_A	296_Q	0.918	0.84
106_A	110_L	0.913	0.84
316_S	348_V	0.912	0.84
98_A	127_V	0.912	0.84
83_T	269_L	0.911	0.83
151_V	174_H	0.907	0.83
94_T	122_A	0.906	0.83
282_W	286_Q	0.902	0.83
230_D	253_D	0.897	0.83
211_H	284_T	0.896	0.82
251_F	266_A	0.895	0.82
57_S	280_D	0.894	0.82
361_E	426_A	0.893	0.82
82_A	220_A	0.891	0.82
124_R	238_E	0.891	0.82
215_T	374_A	0.890	0.82
132_V	139_A	0.888	0.82
189_P	204_H	0.888	0.82
60_M	65_E	0.887	0.82
98_A	150_Y	0.885	0.82
67_L	288_L	0.885	0.82
312_H	421_E	0.884	0.82
46_Q	53_G	0.881	0.81
365_A	408_V	0.876	0.81
140_Y	169_I	0.873	0.81
94_T	98_A	0.872	0.81
104_V	118_L	0.870	0.81
382_A	394_Q	0.870	0.81
332_A	340_Y	0.869	0.80
329_H	340_Y	0.866	0.80
107_A	134_V	0.866	0.80
358_V	420_L	0.865	0.80
276_Q	284_T	0.865	0.80
67_L	210_I	0.864	0.80
59_L	266_A	0.862	0.80
182_V	199_A	0.861	0.80
104_V	129_T	0.860	0.80
306_A	323_L	0.860	0.80
106_A	129_T	0.855	0.79
358_V	362_T	0.855	0.79
192_A	197_H	0.855	0.79
305_V	408_V	0.855	0.79
105_V	151_V	0.853	0.79
80_A	222_V	0.852	0.79
186_F	343_M	0.846	0.79
314_N	425_E	0.838	0.78
343_M	371_V	0.838	0.78
94_T	181_L	0.836	0.78
116_T	245_A	0.836	0.78
304_L	414_A	0.835	0.78
243_N	251_F	0.835	0.78
26_A	375_K	0.830	0.77
48_A	387_Q	0.829	0.77
168_R	171_D	0.829	0.77
192_A	336_L	0.827	0.77
309_L	346_F	0.826	0.77
250_T	254_R	0.822	0.77
299_C	303_Q	0.821	0.77
316_S	347_G	0.821	0.77
7_L	11_S	0.820	0.76
92_L	272_L	0.818	0.76
210_I	284_T	0.818	0.76
90_L	203_W	0.818	0.76
306_A	322_G	0.817	0.76
215_T	286_Q	0.817	0.76
322_G	340_Y	0.813	0.76
423_A	426_A	0.812	0.76
299_C	302_A	0.811	0.76
246_Y	388_Q	0.809	0.76
163_T	336_L	0.807	0.75
134_V	140_Y	0.804	0.75
187_A	192_A	0.802	0.75
76_G	196_D	0.800	0.75
395_R	400_R	0.800	0.75
270_R	388_Q	0.797	0.74
177_G	228_D	0.795	0.74
261_T	264_A	0.793	0.74
151_V	169_I	0.792	0.74
130_T	147_D	0.792	0.74
413_P	416_I	0.791	0.74
102_D	147_D	0.789	0.74
46_Q	54_Y	0.787	0.73
308_H	417_V	0.787	0.73
97_L	239_I	0.786	0.73
218_G	284_T	0.786	0.73
57_S	216_T	0.786	0.73
209_W	344_L	0.785	0.73
298_H	342_G	0.785	0.73
418_A	421_E	0.782	0.73
90_L	152_L	0.779	0.73
314_N	426_A	0.779	0.73
360_E	367_L	0.776	0.72
91_D	117_Y	0.771	0.72
16_Q	20_P	0.770	0.72
119_T	131_F	0.768	0.72
78_V	224_A	0.767	0.72
299_C	342_G	0.766	0.71
297_Q	300_R	0.761	0.71
303_Q	310_R	0.759	0.71
329_H	332_A	0.758	0.71
216_T	277_S	0.755	0.70
34_S	368_L	0.751	0.70
139_A	142_D	0.750	0.70
308_H	424_I	0.748	0.70
67_L	71_L	0.744	0.69
168_R	331_N	0.732	0.68
141_A	172_I	0.732	0.68
190_A	338_S	0.729	0.68
352_Y	394_Q	0.729	0.68
204_H	220_A	0.726	0.67
164_P	331_N	0.721	0.67
322_G	329_H	0.717	0.66
71_L	288_L	0.717	0.66
171_D	174_H	0.715	0.66
239_I	250_T	0.715	0.66
376_T	420_L	0.714	0.66
255_F	262_Y	0.714	0.66
376_T	408_V	0.714	0.66
38_E	51_R	0.712	0.66
290_T	293_L	0.712	0.66
166_L	170_A	0.710	0.66
151_V	172_I	0.709	0.66
356_Q	383_S	0.708	0.65
359_T	367_L	0.708	0.65
170_A	199_A	0.708	0.65
188_T	191_L	0.703	0.65
46_Q	51_R	0.703	0.65
307_E	310_R	0.702	0.65
186_F	209_W	0.700	0.65
8_H	414_A	0.698	0.64
164_P	182_V	0.697	0.64
119_T	123_Q	0.697	0.64
353_E	357_S	0.696	0.64
88_A	274_N	0.696	0.64
308_H	311_D	0.695	0.64
392_E	396_A	0.695	0.64
155_T	166_L	0.691	0.64
52_D	257_D	0.689	0.63
130_T	146_A	0.686	0.63
344_L	406_V	0.685	0.63
117_Y	121_S	0.685	0.63
169_I	172_I	0.684	0.63
40_S	359_T	0.681	0.62
258_A	261_T	0.680	0.62
356_Q	360_E	0.676	0.62
395_R	401_P	0.675	0.62
34_S	370_N	0.674	0.62
320_Y	342_G	0.672	0.61
16_Q	25_R	0.669	0.61
96_L	201_I	0.669	0.61
331_N	335_Y	0.668	0.61
293_L	410_I	0.667	0.61
292_P	296_Q	0.666	0.61
178_V	235_D	0.666	0.61
78_V	257_D	0.666	0.61
124_R	263_A	0.666	0.61
147_D	235_D	0.663	0.60
24_A	32_T	0.663	0.60
422_T	426_A	0.663	0.60
16_Q	27_P	0.662	0.60
71_L	82_A	0.660	0.60
310_R	323_L	0.659	0.60
66_T	285_L	0.658	0.60
85_S	217_V	0.656	0.60
59_L	217_V	0.656	0.60
351_G	402_E	0.656	0.60
319_N	345_T	0.654	0.59
295_M	372_G	0.653	0.59
144_I	172_I	0.652	0.59
174_H	226_S	0.647	0.58
151_V	173_A	0.644	0.58
215_T	283_Q	0.644	0.58
177_G	231_A	0.644	0.58
26_A	215_T	0.644	0.58
97_L	201_I	0.643	0.58
72_A	222_V	0.643	0.58
276_Q	280_D	0.642	0.58
9_T	364_L	0.642	0.58
37_F	43_A	0.641	0.58
139_A	169_I	0.641	0.58
18_V	36_A	0.641	0.58
323_L	329_H	0.640	0.58
414_A	417_V	0.639	0.58
64_V	81_V	0.639	0.58
299_C	337_D	0.639	0.58
421_E	424_I	0.638	0.57
179_P	229_W	0.636	0.57
361_E	423_A	0.636	0.57
341_G	369_A	0.636	0.57
46_Q	60_M	0.635	0.57
135_L	139_A	0.633	0.57
98_A	149_A	0.632	0.57
55_I	59_L	0.630	0.56
133_D	139_A	0.630	0.56
16_Q	375_K	0.628	0.56
16_Q	36_A	0.628	0.56
350_D	354_A	0.627	0.56
393_A	396_A	0.626	0.56
331_N	334_T	0.626	0.56
352_Y	401_P	0.624	0.56
57_S	275_Q	0.623	0.56
49_L	246_Y	0.623	0.56
8_H	296_Q	0.623	0.56
378_V	406_V	0.623	0.56
307_E	311_D	0.621	0.55
209_W	371_V	0.620	0.55
229_W	239_I	0.619	0.55
49_L	388_Q	0.618	0.55
224_A	261_T	0.618	0.55
217_V	284_T	0.616	0.55
123_Q	129_T	0.616	0.55
116_T	120_H	0.616	0.55
306_A	318_V	0.616	0.55
304_L	308_H	0.614	0.55
224_A	229_W	0.613	0.54
23_G	36_A	0.612	0.54
378_V	420_L	0.612	0.54
166_L	199_A	0.612	0.54
243_N	263_A	0.612	0.54
173_A	200_D	0.611	0.54
295_M	299_C	0.611	0.54
325_D	329_H	0.610	0.54
57_S	278_P	0.609	0.54
206_T	211_H	0.607	0.54
299_C	340_Y	0.607	0.54
79_G	258_A	0.607	0.54
305_V	308_H	0.605	0.53
99_R	102_D	0.604	0.53
80_A	220_A	0.604	0.53
379_I	384_T	0.601	0.53
166_L	197_H	0.601	0.53
31_Q	280_D	0.600	0.53
195_I	223_D	0.599	0.53
394_Q	399_V	0.599	0.53
218_G	276_Q	0.598	0.53
316_S	350_D	0.598	0.53
103_S	143_A	0.598	0.53
97_L	263_A	0.597	0.52
93_A	203_W	0.594	0.52
111_Y	386_H	0.593	0.52
387_Q	394_Q	0.593	0.52
16_Q	66_T	0.593	0.52
54_Y	65_E	0.593	0.52
104_V	150_Y	0.592	0.52
45_G	48_A	0.591	0.52
223_D	227_F	0.589	0.52
204_H	222_V	0.588	0.51
354_A	402_E	0.588	0.51
67_L	285_L	0.586	0.51
105_V	132_V	0.585	0.51
141_A	144_I	0.584	0.51
118_L	127_V	0.583	0.51
119_T	393_A	0.583	0.51
209_W	343_M	0.582	0.51
13_H	375_K	0.582	0.51
109_D	134_V	0.582	0.51
306_A	344_L	0.582	0.51
194_P	202_V	0.581	0.51
216_T	279_F	0.578	0.50
296_Q	412_D	0.577	0.50
315_V	346_F	0.577	0.50
225_G	229_W	0.577	0.50
322_G	332_A	0.577	0.50
346_F	406_V	0.577	0.50
207_T	370_N	0.577	0.50
128_D	147_D	0.576	0.50
293_L	296_Q	0.575	0.50
25_R	33_T	0.574	0.50
362_T	365_A	0.573	0.50
161_L	345_T	0.572	0.49
209_W	341_G	0.570	0.49
330_D	334_T	0.570	0.49
11_S	299_C	0.570	0.49
368_L	375_K	0.570	0.49
390_T	394_Q	0.570	0.49
299_C	320_Y	0.569	0.49
55_I	60_M	0.567	0.49
82_A	276_Q	0.566	0.49
346_F	404_V	0.566	0.49
33_T	217_V	0.565	0.49
37_F	42_D	0.563	0.48
303_Q	324_A	0.562	0.48
302_A	322_G	0.562	0.48
262_Y	266_A	0.560	0.48
211_H	216_T	0.560	0.48
92_L	264_A	0.560	0.48
8_H	297_Q	0.560	0.48
43_A	369_A	0.558	0.48
195_I	226_S	0.558	0.48
170_A	197_H	0.558	0.48
83_T	276_Q	0.557	0.48
184_N	204_H	0.557	0.48
6_G	10_N	0.555	0.47
92_L	271_D	0.553	0.47
16_Q	19_D	0.553	0.47
236_Y	239_I	0.550	0.47
352_Y	383_S	0.549	0.47
66_T	69_D	0.549	0.47
109_D	160_S	0.549	0.47
13_H	19_D	0.549	0.47
376_T	406_V	0.549	0.47
35_Y	55_I	0.549	0.47
87_M	117_Y	0.548	0.47
16_Q	285_L	0.548	0.47
81_V	269_L	0.548	0.47
107_A	162_I	0.547	0.46
11_S	190_A	0.546	0.46
88_A	275_Q	0.545	0.46
90_L	93_A	0.545	0.46
26_A	282_W	0.544	0.46
328_T	331_N	0.543	0.46
46_Q	55_I	0.543	0.46
167_E	196_D	0.540	0.46
41_A	51_R	0.540	0.46
121_S	272_L	0.540	0.46
206_T	210_I	0.540	0.46
239_I	259_A	0.539	0.45
268_G	271_D	0.539	0.45
414_A	418_A	0.538	0.45
59_L	275_Q	0.537	0.45
239_I	260_F	0.537	0.45
226_S	311_D	0.534	0.45
163_T	328_T	0.532	0.45
344_L	403_M	0.532	0.45
88_A	92_L	0.532	0.45
107_A	164_P	0.530	0.44
133_D	136_D	0.530	0.44
150_Y	178_V	0.530	0.44
188_T	295_M	0.529	0.44
246_Y	270_R	0.528	0.44
155_T	192_A	0.527	0.44
170_A	200_D	0.526	0.44
254_R	262_Y	0.526	0.44
156_V	340_Y	0.525	0.44
310_R	324_A	0.525	0.44
229_W	259_A	0.525	0.44
27_P	67_L	0.525	0.44
223_D	226_S	0.523	0.44
336_L	340_Y	0.523	0.44
118_L	152_L	0.522	0.43
166_L	174_H	0.522	0.43
25_R	368_L	0.521	0.43
115_V	119_T	0.521	0.43
142_D	146_A	0.520	0.43
352_Y	391_P	0.519	0.43
156_V	336_L	0.517	0.43
49_L	266_A	0.517	0.43
252_T	259_A	0.516	0.43
135_L	327_D	0.516	0.43
370_N	379_I	0.516	0.43
210_I	218_G	0.516	0.43
81_V	265_I	0.516	0.43
116_T	271_D	0.514	0.43
189_P	295_M	0.514	0.43
107_A	140_Y	0.513	0.42
177_G	235_D	0.513	0.42
39_D	42_D	0.512	0.42
362_T	424_I	0.511	0.42
207_T	217_V	0.511	0.42
135_L	326_H	0.510	0.42
78_V	262_Y	0.510	0.42
249_V	255_F	0.510	0.42
5_H	10_N	0.510	0.42
410_I	416_I	0.510	0.42
217_V	275_Q	0.509	0.42
370_N	377_L	0.508	0.42
397_G	400_R	0.508	0.42
72_A	79_G	0.507	0.42
166_L	335_Y	0.507	0.42
34_S	211_H	0.506	0.42
107_A	397_G	0.505	0.41
141_A	171_D	0.505	0.41
179_P	227_F	0.504	0.41
358_V	404_V	0.503	0.41
57_S	281_A	0.502	0.41
88_A	91_D	0.502	0.41
157_G	345_T	0.501	0.41
163_T	192_A	0.501	0.41
151_V	176_N	0.500	0.41

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4kamA	4	0.9026	100	0.535	Contact Map
3ri6A	4	0.8167	100	0.538	Contact Map
1ibjA	4	0.8817	100	0.54	Contact Map
1qgnA	4	0.9072	100	0.548	Contact Map
3cogA	4	0.9002	100	0.574	Contact Map
4oc9A	5	0.9745	100	0.58	Contact Map
4iy7A	4	0.884	100	0.58	Contact Map
1e5eA	4	0.9095	100	0.593	Contact Map
4itxA	4	0.8979	100	0.596	Contact Map
2ctzA	4	0.9722	100	0.606	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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