GREMLIN Database
Q9HMR0 - Phosphoglycerate dehydrogenase
UniProt: Q9HMR0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 527 (517)
Sequences: 1460 (789)
Seq/√Len: 34.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
234_D237_A5.8131.00
222_G247_I5.0381.00
58_F67_V4.6581.00
213_E240_D4.6071.00
25_T42_A4.3181.00
112_A196_F4.0681.00
111_A249_G3.9791.00
188_E218_R3.9671.00
47_V77_I3.9601.00
45_L53_V3.8621.00
212_G215_E3.8411.00
183_E193_R3.6731.00
209_G234_D3.3701.00
186_D189_T3.2481.00
239_A269_A3.1921.00
473_T509_E3.1621.00
199_I232_V3.1311.00
243_Q269_A3.1301.00
242_A271_S2.9691.00
331_E370_Q2.9661.00
239_A243_Q2.9281.00
197_L222_G2.8571.00
185_V190_C2.8301.00
142_L158_L2.8261.00
32_G56_A2.7981.00
221_G247_I2.6701.00
498_L502_V2.6581.00
368_A413_V2.6011.00
31_T34_A2.5891.00
216_L246_V2.5801.00
58_F87_V2.5241.00
203_L208_D2.5001.00
209_G256_R2.4711.00
67_V87_V2.4201.00
216_L219_M2.4151.00
223_Y248_A2.4081.00
465_G468_G2.3230.99
128_A131_D2.3100.99
119_H123_D2.2770.99
196_F223_Y2.2670.99
191_V219_M2.2380.99
11_D15_D2.2190.99
36_L56_A2.2120.99
219_M222_G2.2070.99
348_V372_A2.2040.99
36_L60_A2.1500.99
105_V158_L2.1450.99
192_A218_R2.1210.99
105_V161_L2.1050.99
142_L163_M2.0880.99
15_D19_D2.0810.99
55_D59_E2.0670.99
438_E441_G2.0630.99
347_R416_G2.0600.99
36_L57_V2.0540.98
111_A223_Y2.0440.98
479_A485_R2.0070.98
465_G472_G2.0020.98
122_L274_T1.9780.98
217_A244_D1.9710.98
219_M246_V1.9520.98
55_D84_D1.9500.98
485_R489_G1.9290.98
483_N494_T1.9280.98
166_V185_V1.8890.97
422_L440_D1.8860.97
410_L437_V1.8780.97
211_I216_L1.8680.97
111_A251_A1.8400.97
10_A287_E1.8310.97
164_D183_E1.8300.97
369_Q396_V1.8300.97
43_H63_D1.8240.97
508_D512_G1.8190.97
143_G190_C1.8100.97
191_V215_E1.8060.97
104_T227_V1.7920.96
27_A38_A1.7840.96
138_S162_G1.7810.96
123_D268_D1.7800.96
32_G36_L1.7600.96
337_A415_V1.7570.96
38_A42_A1.7570.96
109_F161_L1.7540.96
32_G54_T1.7420.96
243_Q271_S1.7310.96
269_A272_I1.7290.96
39_V62_P1.7040.95
213_E237_A1.6920.95
209_G212_G1.6860.95
44_A297_V1.6770.95
39_V42_A1.6730.95
243_Q268_D1.6630.94
508_D511_A1.6470.94
410_L425_S1.6370.94
25_T38_A1.6090.93
103_H107_L1.6090.93
255_F274_T1.6040.93
121_R132_Y1.6030.93
221_G244_D1.5970.93
242_A269_A1.5960.93
212_G237_A1.5920.93
212_G234_D1.5900.93
3_V22_H1.5900.93
111_A273_I1.5630.92
191_V211_I1.5630.92
68_A293_T1.5600.92
239_A252_L1.5590.92
135_T223_Y1.5520.92
177_A184_L1.5430.92
141_T164_D1.5400.92
53_V67_V1.5340.92
474_A509_E1.5340.92
106_A115_I1.5330.92
120_A124_A1.5310.92
241_A247_I1.5310.92
135_T196_F1.5080.91
440_D456_R1.4730.90
20_A302_A1.4710.90
143_G194_A1.4700.90
41_D63_D1.4670.90
34_A37_D1.4600.89
454_V495_V1.4580.89
116_P273_I1.4570.89
504_A508_D1.4530.89
211_I219_M1.4460.89
236_D265_P1.4420.89
185_V193_R1.4390.89
62_P85_H1.4110.88
84_D391_E1.4100.88
27_A30_A1.4040.88
166_V193_R1.4030.87
144_V155_A1.3950.87
330_A411_V1.3860.87
348_V369_Q1.3800.87
107_L115_I1.3760.86
233_V252_L1.3680.86
214_A218_R1.3670.86
121_R126_S1.3670.86
74_V77_I1.3660.86
145_V199_I1.3640.86
223_Y249_G1.3480.85
174_E178_A1.3470.85
216_L241_A1.3450.85
260_L267_H1.3400.85
103_H115_I1.3380.85
217_A246_V1.3280.84
8_P130_D1.3250.84
95_G289_V1.3220.84
6_T45_L1.3120.84
11_D18_R1.3090.84
236_D240_D1.3080.83
300_A306_V1.3070.83
481_M494_T1.2930.83
299_A304_D1.2900.83
103_H106_A1.2880.83
352_Y365_T1.2850.82
349_D397_T1.2570.81
8_P50_G1.2560.81
342_D520_T1.2520.81
54_T57_V1.2520.81
462_G468_G1.2500.81
239_A265_P1.2420.80
459_D492_A1.2400.80
107_L227_V1.2370.80
242_A272_I1.2370.80
5_V13_G1.2300.79
231_G235_E1.2250.79
300_A303_G1.2230.79
412_S425_S1.2200.79
221_G245_G1.2190.79
59_E81_A1.2130.79
240_D243_Q1.2060.78
205_D208_D1.2020.78
213_E244_D1.2010.78
33_D56_A1.1960.78
22_H298_V1.1940.77
252_L272_I1.1920.77
221_G246_V1.1830.77
239_A268_D1.1820.77
414_T421_E1.1690.76
369_Q386_P1.1660.76
122_L267_H1.1660.76
349_D414_T1.1610.75
210_L252_L1.1580.75
27_A34_A1.1550.75
485_R492_A1.1530.75
213_E217_A1.1500.75
343_P419_D1.1490.75
298_V302_A1.1370.74
416_G421_E1.1360.74
95_G290_A1.1350.74
352_Y398_E1.1350.74
103_H275_T1.1270.73
236_D264_S1.1140.72
61_A85_H1.1110.72
38_A41_D1.1050.72
352_Y361_V1.0910.71
453_L498_L1.0860.70
503_P506_A1.0840.70
330_A368_A1.0800.70
55_D81_A1.0690.69
187_I191_V1.0660.69
236_D256_R1.0640.69
333_A436_L1.0600.68
211_I224_V1.0600.68
158_L163_M1.0570.68
40_S60_A1.0560.68
222_G246_V1.0550.68
90_A494_T1.0510.68
12_A287_E1.0490.68
141_T166_V1.0460.67
59_E85_H1.0420.67
144_V198_T1.0410.67
25_T39_V1.0390.67
215_E218_R1.0350.67
479_A499_D1.0300.66
457_N494_T1.0300.66
329_L426_G1.0300.66
469_G473_T1.0280.66
30_A34_A1.0270.66
239_A242_A1.0180.65
297_V301_L1.0180.65
210_L232_V1.0170.65
177_A182_A1.0140.65
470_V510_L1.0090.65
260_L264_S1.0090.65
456_R491_E1.0080.64
145_V211_I1.0080.64
45_L57_V1.0070.64
510_L519_V1.0040.64
90_A101_A1.0020.64
47_V53_V1.0010.64
346_E418_G1.0000.64
153_E156_T0.9980.64
466_F515_R0.9950.63
459_D462_G0.9940.63
189_T193_R0.9910.63
257_T261_P0.9890.63
224_V233_V0.9890.63
436_L448_P0.9880.63
106_A109_F0.9870.63
6_T53_V0.9820.62
457_N483_N0.9790.62
240_D244_D0.9750.62
351_T414_T0.9680.61
167_A182_A0.9670.61
451_H521_S0.9640.61
152_Q176_R0.9620.61
389_A396_V0.9610.61
216_L224_V0.9600.61
122_L255_F0.9580.60
147_L182_A0.9580.60
190_C194_A0.9580.60
219_M247_I0.9560.60
159_D165_L0.9530.60
211_I215_E0.9520.60
17_L297_V0.9520.60
251_A273_I0.9480.60
58_F85_H0.9430.59
425_S438_E0.9420.59
296_Q457_N0.9410.59
171_Y210_L0.9400.59
121_R128_A0.9360.59
485_R499_D0.9350.59
29_D34_A0.9340.58
118_A132_Y0.9290.58
424_V436_L0.9290.58
99_A161_L0.9280.58
153_E157_R0.9260.58
214_A237_A0.9210.57
112_A135_T0.9180.57
333_A336_V0.9150.57
77_I149_R0.9150.57
194_A197_L0.9110.57
343_P418_G0.9110.57
40_S62_P0.9100.56
90_A293_T0.9100.56
370_Q382_A0.9070.56
347_R395_A0.9060.56
507_L519_V0.9060.56
476_V506_A0.9060.56
350_V368_A0.9060.56
6_T47_V0.9050.56
117_Q273_I0.9050.56
96_N100_A0.9040.56
188_E214_A0.9010.56
111_A248_A0.9000.56
241_A246_V0.9000.56
474_A506_A0.8990.56
306_V312_A0.8970.55
99_A129_K0.8960.55
7_D290_A0.8940.55
188_E192_A0.8920.55
219_M244_D0.8900.55
502_V506_A0.8880.55
159_D181_G0.8840.54
165_L182_A0.8810.54
479_A489_G0.8760.54
330_A364_V0.8760.54
147_L172_I0.8740.53
509_E512_G0.8740.53
183_E189_T0.8740.53
157_R161_L0.8730.53
117_Q251_A0.8700.53
463_V480_G0.8650.53
191_V222_G0.8640.53
232_V481_M0.8600.52
39_V53_V0.8560.52
187_I211_I0.8530.52
166_V190_C0.8510.51
58_F81_A0.8510.51
125_G268_D0.8490.51
244_D504_A0.8460.51
136_E288_N0.8450.51
479_A492_A0.8380.50
145_V190_C0.8380.50
107_L251_A0.8370.50
83_T281_S0.8340.50
50_G150_V0.8320.50
17_L46_I0.8310.50
214_A236_D0.8310.50
329_L333_A0.8310.50
12_A15_D0.8300.50
103_H251_A0.8290.50
462_G492_A0.8270.49
46_I297_V0.8270.49
13_G17_L0.8260.49
106_A278_L0.8250.49
42_A62_P0.8240.49
332_T450_G0.8230.49
23_E26_T0.8220.49
466_F513_D0.8210.49
30_A38_A0.8210.49
20_A298_V0.8200.49
107_L116_P0.8190.49
5_V14_L0.8140.48
486_E491_E0.8130.48
137_L161_L0.8110.48
98_R138_S0.8100.48
121_R124_A0.8060.48
72_I94_A0.8050.48
335_T339_A0.8040.47
47_V80_D0.8040.47
222_G242_A0.8030.47
117_Q132_Y0.8030.47
440_D467_I0.8010.47
187_I190_C0.8010.47
152_Q182_A0.8000.47
6_T28_Y0.7930.47
333_A413_V0.7930.47
67_V77_I0.7930.47
280_A286_Q0.7920.46
87_V395_A0.7920.46
142_L198_T0.7920.46
47_V83_T0.7910.46
328_D331_E0.7890.46
137_L196_F0.7880.46
117_Q270_D0.7880.46
214_A217_A0.7870.46
239_A271_S0.7850.46
101_A434_P0.7830.46
188_E215_E0.7830.46
72_I92_A0.7820.46
7_D106_A0.7810.46
233_V247_I0.7810.46
110_A265_P0.7800.45
153_E203_L0.7800.45
224_V247_I0.7780.45
119_H273_I0.7770.45
123_D274_T0.7760.45
48_R69_R0.7760.45
147_L167_A0.7750.45
370_Q374_A0.7740.45
459_D477_N0.7730.45
39_V61_A0.7710.45
278_L281_S0.7700.45
467_I494_T0.7680.44
500_A510_L0.7670.44
230_G259_P0.7650.44
484_A489_G0.7630.44
468_G472_G0.7610.44
66_I90_A0.7610.44
100_A105_V0.7600.44
53_V110_A0.7580.44
129_K303_G0.7580.44
39_V45_L0.7580.44
396_V469_G0.7560.43
47_V281_S0.7560.43
9_I160_S0.7550.43
58_F62_P0.7540.43
156_T162_G0.7520.43
444_V473_T0.7480.43
267_H274_T0.7470.43
367_A507_L0.7460.43
355_E409_S0.7460.43
99_A147_L0.7450.42
117_Q121_R0.7450.42
154_V198_T0.7440.42
483_N492_A0.7430.42
333_A424_V0.7420.42
464_I483_N0.7410.42
90_A297_V0.7410.42
231_G280_A0.7390.42
464_I481_M0.7370.42
33_D40_S0.7350.42
110_A116_P0.7340.42
197_L325_P0.7330.42
48_R73_G0.7320.41
445_E448_P0.7320.41
410_L427_T0.7310.41
459_D479_A0.7300.41
485_R490_G0.7300.41
95_G435_R0.7300.41
197_L218_R0.7290.41
90_A296_Q0.7290.41
39_V57_V0.7290.41
435_R479_A0.7280.41
9_I287_E0.7280.41
477_N499_D0.7270.41
175_D251_A0.7260.41
105_V160_S0.7260.41
121_R131_D0.7260.41
95_G288_N0.7240.41
100_A129_K0.7230.41
213_E246_V0.7230.41
337_A340_L0.7230.41
90_A308_N0.7210.41
456_R518_D0.7190.40
103_H108_A0.7190.40
56_A59_E0.7180.40
289_V457_N0.7170.40
107_L201_V0.7170.40
68_A440_D0.7150.40
96_N229_R0.7140.40
4_L82_A0.7140.40
261_P267_H0.7130.40
66_I300_A0.7120.40
107_L273_I0.7110.40
238_L247_I0.7110.40
37_D60_A0.7080.39
4_L42_A0.7080.39
13_G16_R0.7070.39
264_S267_H0.7060.39
77_I121_R0.7050.39
123_D270_D0.7040.39
144_V154_V0.7040.39
99_A156_T0.7040.39
100_A255_F0.7030.39
182_A233_V0.7030.39
55_D345_I0.7020.39
445_E494_T0.7010.39
197_L247_I0.7000.39
119_H274_T0.6990.39
380_V388_V0.6990.39
144_V201_V0.6980.39
457_N481_M0.6980.39
348_V415_V0.6960.38
90_A306_V0.6960.38
66_I303_G0.6960.38
174_E184_L0.6900.38
505_R509_E0.6870.38
92_A292_D0.6860.38
236_D506_A0.6850.38
337_A341_F0.6840.38
271_S473_T0.6830.37
90_A303_G0.6790.37
368_A372_A0.6760.37
375_G392_R0.6750.37
328_D332_T0.6730.37
73_G254_V0.6720.37
65_V495_V0.6720.37
494_T515_R0.6710.36
29_D38_A0.6700.36
123_D510_L0.6700.36
16_R296_Q0.6700.36
88_M394_I0.6680.36
273_I431_G0.6680.36
9_I46_I0.6680.36
83_T387_R0.6670.36
196_F225_I0.6660.36
36_L58_F0.6650.36
77_I138_S0.6640.36
115_I132_Y0.6620.36
17_L129_K0.6610.36
100_A106_A0.6610.36
260_L263_A0.6610.36
491_E517_V0.6600.36
349_D399_T0.6580.35
236_D263_A0.6580.35
237_A432_D0.6580.35
129_K446_A0.6580.35
296_Q308_N0.6570.35
442_F481_M0.6560.35
455_A494_T0.6540.35
346_E424_V0.6540.35
17_L149_R0.6540.35
147_L184_L0.6530.35
326_F409_S0.6530.35
72_I129_K0.6530.35
66_I297_V0.6510.35
83_T483_N0.6500.35
460_T463_V0.6490.35
67_V380_V0.6480.35
341_F420_A0.6470.35
338_A372_A0.6470.35
10_A177_A0.6460.35
74_V79_I0.6440.34
131_D270_D0.6440.34
316_E319_A0.6430.34
263_A268_D0.6430.34
345_I394_I0.6430.34
92_A157_R0.6420.34
80_D84_D0.6420.34
35_L39_V0.6420.34
442_F497_N0.6400.34
504_A521_S0.6400.34
162_G296_Q0.6400.34
275_T289_V0.6400.34
336_V340_L0.6390.34
30_A42_A0.6390.34
101_A153_E0.6360.34
348_V413_V0.6350.34
299_A307_V0.6350.34
453_L502_V0.6330.34
323_I437_V0.6330.34
15_D18_R0.6320.33
300_A366_A0.6310.33
333_A355_E0.6310.33
387_R409_S0.6290.33
74_V381_N0.6290.33
451_H501_D0.6270.33
112_A223_Y0.6270.33
46_I298_V0.6260.33
92_A296_Q0.6250.33
448_P463_V0.6250.33
192_A343_P0.6230.33
145_V187_I0.6230.33
28_Y46_I0.6220.33
233_V421_E0.6220.33
334_G371_G0.6200.33
103_H116_P0.6190.32
55_D210_L0.6180.32
369_Q389_A0.6180.32
145_V210_L0.6170.32
225_I249_G0.6170.32
3_V334_G0.6160.32
466_F473_T0.6160.32
165_L248_A0.6160.32
144_V456_R0.6160.32
5_V42_A0.6140.32
333_A446_A0.6130.32
222_G245_G0.6130.32
95_G231_G0.6120.32
103_H326_F0.6120.32
116_P251_A0.6120.32
471_L506_A0.6110.32
5_V24_V0.6100.32
9_I178_A0.6090.32
221_G242_A0.6080.32
278_L463_V0.6080.32
16_R295_D0.6080.32
428_L437_V0.6070.32
233_V250_A0.6060.31
10_A14_L0.6060.31
333_A426_G0.6060.31
66_I301_L0.6060.31
111_A225_I0.6050.31
238_L252_L0.6050.31
405_E429_F0.6040.31
53_V57_V0.6040.31
103_H278_L0.6030.31
11_D517_V0.6030.31
166_V194_A0.6000.31
82_A107_L0.6000.31
300_A304_D0.5990.31
26_T476_V0.5980.31
312_A366_A0.5980.31
215_E219_M0.5980.31
411_V516_I0.5970.31
77_I315_A0.5970.31
376_L392_R0.5970.31
191_V210_L0.5960.31
99_A153_E0.5950.31
70_A73_G0.5950.31
11_D26_T0.5950.31
152_Q204_T0.5940.31
466_F469_G0.5940.31
184_L344_R0.5910.30
327_V428_L0.5900.30
205_D382_A0.5890.30
13_G46_I0.5870.30
234_D310_L0.5870.30
142_L310_L0.5860.30
180_L232_V0.5860.30
172_I498_L0.5860.30
495_V498_L0.5840.30
59_E270_D0.5840.30
44_A481_M0.5840.30
351_T412_S0.5840.30
196_F248_A0.5830.30
92_A445_E0.5830.30
306_V319_A0.5830.30
230_G258_E0.5820.30
373_F394_I0.5820.30
232_V347_R0.5800.30
216_L247_I0.5800.30
241_A250_A0.5790.30
60_A63_D0.5790.30
47_V145_V0.5780.29
176_R274_T0.5760.29
40_S63_D0.5750.29
457_N482_F0.5750.29
218_R475_E0.5740.29
132_Y271_S0.5730.29
171_Y290_A0.5730.29
123_D239_A0.5720.29
346_E416_G0.5710.29
48_R229_R0.5710.29
73_G76_N0.5710.29
147_L442_F0.5700.29
100_A289_V0.5700.29
144_V187_I0.5690.29
3_V19_D0.5680.29
27_A42_A0.5680.29
453_L471_L0.5660.29
465_G469_G0.5650.29
13_G103_H0.5650.29
331_E371_G0.5640.28
342_D419_D0.5630.28
33_D508_D0.5620.28
47_V137_L0.5620.28
105_V142_L0.5620.28
144_V501_D0.5610.28
65_V145_V0.5600.28
6_T51_T0.5600.28
480_G497_N0.5600.28
176_R180_L0.5600.28
173_G248_A0.5600.28
384_N389_A0.5590.28
171_Y337_A0.5590.28
137_L210_L0.5590.28
158_L273_I0.5580.28
479_A497_N0.5570.28
377_E388_V0.5570.28
23_E475_E0.5560.28
3_V424_V0.5550.28
242_A419_D0.5530.28
174_E217_A0.5530.28
99_A300_A0.5530.28
114_S117_Q0.5520.28
99_A104_T0.5520.28
202_P231_G0.5520.28
36_L40_S0.5520.28
13_G298_V0.5520.28
135_T248_A0.5510.28
336_V422_L0.5510.28
147_L152_Q0.5510.28
115_I251_A0.5510.28
319_A360_D0.5500.28
365_T398_E0.5490.27
17_L100_A0.5490.27
66_I88_M0.5490.27
261_P264_S0.5480.27
396_V475_E0.5480.27
108_A519_V0.5470.27
99_A290_A0.5460.27
72_I153_E0.5460.27
335_T374_A0.5460.27
143_G467_I0.5460.27
201_V210_L0.5450.27
48_R280_A0.5450.27
240_D469_G0.5450.27
34_A38_A0.5430.27
345_I444_V0.5430.27
41_D62_P0.5430.27
5_V98_R0.5430.27
191_V216_L0.5420.27
288_N296_Q0.5420.27
13_G291_T0.5420.27
48_R277_H0.5420.27
122_L312_A0.5410.27
361_V400_K0.5410.27
437_V440_D0.5410.27
173_G212_G0.5400.27
361_V398_E0.5400.27
458_H517_V0.5400.27
9_I315_A0.5390.27
470_V479_A0.5380.27
211_I247_I0.5380.27
165_L501_D0.5370.27
142_L166_V0.5370.27
68_A496_Y0.5360.27
218_R222_G0.5360.27
147_L305_P0.5360.27
109_F160_S0.5360.27
406_A410_L0.5350.27
69_R229_R0.5350.27
459_D485_R0.5350.27
189_T192_A0.5350.27
250_A269_A0.5350.27
157_R445_E0.5330.26
462_G477_N0.5330.26
164_D509_E0.5320.26
152_Q392_R0.5320.26
69_R73_G0.5320.26
222_G244_D0.5310.26
372_A495_V0.5310.26
255_F281_S0.5300.26
90_A304_D0.5300.26
462_G471_L0.5290.26
167_A180_L0.5290.26
105_V109_F0.5260.26
406_A430_A0.5250.26
92_A289_V0.5250.26
466_F470_V0.5240.26
41_D503_P0.5230.26
452_M495_V0.5230.26
474_A505_R0.5230.26
326_F379_Q0.5230.26
502_V505_R0.5220.26
97_V100_A0.5210.26
142_L182_A0.5210.26
326_F384_N0.5190.25
341_F417_N0.5180.25
103_H494_T0.5180.25
100_A227_V0.5180.25
363_L422_L0.5180.25
7_D66_I0.5180.25
250_A383_V0.5180.25
133_L293_T0.5170.25
456_R502_V0.5170.25
349_D416_G0.5170.25
44_A301_L0.5170.25
48_R70_A0.5160.25
385_A389_A0.5160.25
238_L272_I0.5160.25
407_Y437_V0.5150.25
92_A149_R0.5140.25
90_A481_M0.5130.25
272_I355_E0.5120.25
308_N457_N0.5120.25
345_I415_V0.5120.25
36_L39_V0.5120.25
100_A303_G0.5110.25
8_P29_D0.5100.25
18_R519_V0.5100.25
168_Y247_I0.5100.25
141_T510_L0.5090.25
121_R174_E0.5090.25
194_A512_G0.5090.25
19_D476_V0.5080.25
85_H419_D0.5080.25
118_A167_A0.5080.25
184_L440_D0.5070.25
197_L223_Y0.5060.25
66_I464_I0.5060.25
435_R445_E0.5060.25
8_P47_V0.5060.25
371_G388_V0.5060.25
345_I372_A0.5050.25
157_R308_N0.5050.25
66_I302_A0.5040.24
199_I222_G0.5040.24
72_I97_V0.5030.24
55_D78_D0.5030.24
9_I97_V0.5030.24
223_Y251_A0.5020.24
291_T428_L0.5020.24
444_V485_R0.5020.24
228_A231_G0.5010.24
13_G360_D0.5010.24
3_V505_R0.5010.24
85_H413_V0.5010.24
15_D206_E0.5000.24
350_V387_R0.5000.24
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ygyA 4 0.9886 100 0.36 Contact Map
3k5pA 3 0.7324 100 0.568 Contact Map
1sc6A 4 0.7154 100 0.574 Contact Map
2g76A 2 0.5693 100 0.619 Contact Map
2d0iA 2 0.6129 100 0.639 Contact Map
1wwkA 2 0.5712 100 0.642 Contact Map
2w2kA 2 0.6015 100 0.645 Contact Map
3wwyA 4 0.592 100 0.646 Contact Map
2gcgA 2 0.592 100 0.646 Contact Map
4g2nA 3 0.5844 100 0.647 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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