Q9HMR0 - HALSA - GREMLIN Contacts

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Q9HMR0 - Phosphoglycerate dehydrogenase

UniProt:	Q9HMR0	Sequences: MRVLVTDPIADAGLDRLRDAGHEVTTAYDATGDALLDAVSDAHALIVRSGTAVTDAVFEAAPDLVIVARAGIGVDNIDIDAATDHGVMVANAPAGNVRAAAEHTVALAFAAARSIPQAHARLDAGSWAKDDYLGTELSGKTLGVVGLGRVGQEVATRLDSLGMDLVAYDPYIGEDRAAQLGAELVDIETCVARADFLTIHVPLTDETDGLIGEAELARMDGGYVINVARGGVVDEDALADAAQDGVIAGAALDVFRTEPLPAASPLHDADSIITTPHLGASTKAAQENVATDTADQVVAALAGDPVVNALNAPSAERSAFDRIRPFVDLAETAGTVAAALFDPRIERVDVTYQGEVADEDVALVTAAAQQGAFAGLEWQVNAVNAPRVAEERGIAVTETKNHRSEAYQSLVSVTVGNGDAELTVSGTLFAGDDPRLVEIDGFRVEAAPNGHMLVARNHDTPGVIGFIGGVLGTAEVNIAGMFNAREARGGEALTVYNLDADVPARALDELAGDDRIVDVTSIELNGE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	527 (517)
Sequences:	1460 (789)
Seq/√Len:	34.7

ECOLI - SERA
BACSU - SERA
HALSA - Q9HMR0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
234_D	237_A	5.813	1.00
222_G	247_I	5.038	1.00
58_F	67_V	4.658	1.00
213_E	240_D	4.607	1.00
25_T	42_A	4.318	1.00
112_A	196_F	4.068	1.00
111_A	249_G	3.979	1.00
188_E	218_R	3.967	1.00
47_V	77_I	3.960	1.00
45_L	53_V	3.862	1.00
212_G	215_E	3.841	1.00
183_E	193_R	3.673	1.00
209_G	234_D	3.370	1.00
186_D	189_T	3.248	1.00
239_A	269_A	3.192	1.00
473_T	509_E	3.162	1.00
199_I	232_V	3.131	1.00
243_Q	269_A	3.130	1.00
242_A	271_S	2.969	1.00
331_E	370_Q	2.966	1.00
239_A	243_Q	2.928	1.00
197_L	222_G	2.857	1.00
185_V	190_C	2.830	1.00
142_L	158_L	2.826	1.00
32_G	56_A	2.798	1.00
221_G	247_I	2.670	1.00
498_L	502_V	2.658	1.00
368_A	413_V	2.601	1.00
31_T	34_A	2.589	1.00
216_L	246_V	2.580	1.00
58_F	87_V	2.524	1.00
203_L	208_D	2.500	1.00
209_G	256_R	2.471	1.00
67_V	87_V	2.420	1.00
216_L	219_M	2.415	1.00
223_Y	248_A	2.408	1.00
465_G	468_G	2.323	0.99
128_A	131_D	2.310	0.99
119_H	123_D	2.277	0.99
196_F	223_Y	2.267	0.99
191_V	219_M	2.238	0.99
11_D	15_D	2.219	0.99
36_L	56_A	2.212	0.99
219_M	222_G	2.207	0.99
348_V	372_A	2.204	0.99
36_L	60_A	2.150	0.99
105_V	158_L	2.145	0.99
192_A	218_R	2.121	0.99
105_V	161_L	2.105	0.99
142_L	163_M	2.088	0.99
15_D	19_D	2.081	0.99
55_D	59_E	2.067	0.99
438_E	441_G	2.063	0.99
347_R	416_G	2.060	0.99
36_L	57_V	2.054	0.98
111_A	223_Y	2.044	0.98
479_A	485_R	2.007	0.98
465_G	472_G	2.002	0.98
122_L	274_T	1.978	0.98
217_A	244_D	1.971	0.98
219_M	246_V	1.952	0.98
55_D	84_D	1.950	0.98
485_R	489_G	1.929	0.98
483_N	494_T	1.928	0.98
166_V	185_V	1.889	0.97
422_L	440_D	1.886	0.97
410_L	437_V	1.878	0.97
211_I	216_L	1.868	0.97
111_A	251_A	1.840	0.97
10_A	287_E	1.831	0.97
164_D	183_E	1.830	0.97
369_Q	396_V	1.830	0.97
43_H	63_D	1.824	0.97
508_D	512_G	1.819	0.97
143_G	190_C	1.810	0.97
191_V	215_E	1.806	0.97
104_T	227_V	1.792	0.96
27_A	38_A	1.784	0.96
138_S	162_G	1.781	0.96
123_D	268_D	1.780	0.96
32_G	36_L	1.760	0.96
337_A	415_V	1.757	0.96
38_A	42_A	1.757	0.96
109_F	161_L	1.754	0.96
32_G	54_T	1.742	0.96
243_Q	271_S	1.731	0.96
269_A	272_I	1.729	0.96
39_V	62_P	1.704	0.95
213_E	237_A	1.692	0.95
209_G	212_G	1.686	0.95
44_A	297_V	1.677	0.95
39_V	42_A	1.673	0.95
243_Q	268_D	1.663	0.94
508_D	511_A	1.647	0.94
410_L	425_S	1.637	0.94
25_T	38_A	1.609	0.93
103_H	107_L	1.609	0.93
255_F	274_T	1.604	0.93
121_R	132_Y	1.603	0.93
221_G	244_D	1.597	0.93
242_A	269_A	1.596	0.93
212_G	237_A	1.592	0.93
212_G	234_D	1.590	0.93
3_V	22_H	1.590	0.93
111_A	273_I	1.563	0.92
191_V	211_I	1.563	0.92
68_A	293_T	1.560	0.92
239_A	252_L	1.559	0.92
135_T	223_Y	1.552	0.92
177_A	184_L	1.543	0.92
141_T	164_D	1.540	0.92
53_V	67_V	1.534	0.92
474_A	509_E	1.534	0.92
106_A	115_I	1.533	0.92
120_A	124_A	1.531	0.92
241_A	247_I	1.531	0.92
135_T	196_F	1.508	0.91
440_D	456_R	1.473	0.90
20_A	302_A	1.471	0.90
143_G	194_A	1.470	0.90
41_D	63_D	1.467	0.90
34_A	37_D	1.460	0.89
454_V	495_V	1.458	0.89
116_P	273_I	1.457	0.89
504_A	508_D	1.453	0.89
211_I	219_M	1.446	0.89
236_D	265_P	1.442	0.89
185_V	193_R	1.439	0.89
62_P	85_H	1.411	0.88
84_D	391_E	1.410	0.88
27_A	30_A	1.404	0.88
166_V	193_R	1.403	0.87
144_V	155_A	1.395	0.87
330_A	411_V	1.386	0.87
348_V	369_Q	1.380	0.87
107_L	115_I	1.376	0.86
233_V	252_L	1.368	0.86
214_A	218_R	1.367	0.86
121_R	126_S	1.367	0.86
74_V	77_I	1.366	0.86
145_V	199_I	1.364	0.86
223_Y	249_G	1.348	0.85
174_E	178_A	1.347	0.85
216_L	241_A	1.345	0.85
260_L	267_H	1.340	0.85
103_H	115_I	1.338	0.85
217_A	246_V	1.328	0.84
8_P	130_D	1.325	0.84
95_G	289_V	1.322	0.84
6_T	45_L	1.312	0.84
11_D	18_R	1.309	0.84
236_D	240_D	1.308	0.83
300_A	306_V	1.307	0.83
481_M	494_T	1.293	0.83
299_A	304_D	1.290	0.83
103_H	106_A	1.288	0.83
352_Y	365_T	1.285	0.82
349_D	397_T	1.257	0.81
8_P	50_G	1.256	0.81
342_D	520_T	1.252	0.81
54_T	57_V	1.252	0.81
462_G	468_G	1.250	0.81
239_A	265_P	1.242	0.80
459_D	492_A	1.240	0.80
107_L	227_V	1.237	0.80
242_A	272_I	1.237	0.80
5_V	13_G	1.230	0.79
231_G	235_E	1.225	0.79
300_A	303_G	1.223	0.79
412_S	425_S	1.220	0.79
221_G	245_G	1.219	0.79
59_E	81_A	1.213	0.79
240_D	243_Q	1.206	0.78
205_D	208_D	1.202	0.78
213_E	244_D	1.201	0.78
33_D	56_A	1.196	0.78
22_H	298_V	1.194	0.77
252_L	272_I	1.192	0.77
221_G	246_V	1.183	0.77
239_A	268_D	1.182	0.77
414_T	421_E	1.169	0.76
369_Q	386_P	1.166	0.76
122_L	267_H	1.166	0.76
349_D	414_T	1.161	0.75
210_L	252_L	1.158	0.75
27_A	34_A	1.155	0.75
485_R	492_A	1.153	0.75
213_E	217_A	1.150	0.75
343_P	419_D	1.149	0.75
298_V	302_A	1.137	0.74
416_G	421_E	1.136	0.74
95_G	290_A	1.135	0.74
352_Y	398_E	1.135	0.74
103_H	275_T	1.127	0.73
236_D	264_S	1.114	0.72
61_A	85_H	1.111	0.72
38_A	41_D	1.105	0.72
352_Y	361_V	1.091	0.71
453_L	498_L	1.086	0.70
503_P	506_A	1.084	0.70
330_A	368_A	1.080	0.70
55_D	81_A	1.069	0.69
187_I	191_V	1.066	0.69
236_D	256_R	1.064	0.69
333_A	436_L	1.060	0.68
211_I	224_V	1.060	0.68
158_L	163_M	1.057	0.68
40_S	60_A	1.056	0.68
222_G	246_V	1.055	0.68
90_A	494_T	1.051	0.68
12_A	287_E	1.049	0.68
141_T	166_V	1.046	0.67
59_E	85_H	1.042	0.67
144_V	198_T	1.041	0.67
25_T	39_V	1.039	0.67
215_E	218_R	1.035	0.67
479_A	499_D	1.030	0.66
457_N	494_T	1.030	0.66
329_L	426_G	1.030	0.66
469_G	473_T	1.028	0.66
30_A	34_A	1.027	0.66
239_A	242_A	1.018	0.65
297_V	301_L	1.018	0.65
210_L	232_V	1.017	0.65
177_A	182_A	1.014	0.65
470_V	510_L	1.009	0.65
260_L	264_S	1.009	0.65
456_R	491_E	1.008	0.64
145_V	211_I	1.008	0.64
45_L	57_V	1.007	0.64
510_L	519_V	1.004	0.64
90_A	101_A	1.002	0.64
47_V	53_V	1.001	0.64
346_E	418_G	1.000	0.64
153_E	156_T	0.998	0.64
466_F	515_R	0.995	0.63
459_D	462_G	0.994	0.63
189_T	193_R	0.991	0.63
257_T	261_P	0.989	0.63
224_V	233_V	0.989	0.63
436_L	448_P	0.988	0.63
106_A	109_F	0.987	0.63
6_T	53_V	0.982	0.62
457_N	483_N	0.979	0.62
240_D	244_D	0.975	0.62
351_T	414_T	0.968	0.61
167_A	182_A	0.967	0.61
451_H	521_S	0.964	0.61
152_Q	176_R	0.962	0.61
389_A	396_V	0.961	0.61
216_L	224_V	0.960	0.61
122_L	255_F	0.958	0.60
147_L	182_A	0.958	0.60
190_C	194_A	0.958	0.60
219_M	247_I	0.956	0.60
159_D	165_L	0.953	0.60
211_I	215_E	0.952	0.60
17_L	297_V	0.952	0.60
251_A	273_I	0.948	0.60
58_F	85_H	0.943	0.59
425_S	438_E	0.942	0.59
296_Q	457_N	0.941	0.59
171_Y	210_L	0.940	0.59
121_R	128_A	0.936	0.59
485_R	499_D	0.935	0.59
29_D	34_A	0.934	0.58
118_A	132_Y	0.929	0.58
424_V	436_L	0.929	0.58
99_A	161_L	0.928	0.58
153_E	157_R	0.926	0.58
214_A	237_A	0.921	0.57
112_A	135_T	0.918	0.57
333_A	336_V	0.915	0.57
77_I	149_R	0.915	0.57
194_A	197_L	0.911	0.57
343_P	418_G	0.911	0.57
40_S	62_P	0.910	0.56
90_A	293_T	0.910	0.56
370_Q	382_A	0.907	0.56
347_R	395_A	0.906	0.56
507_L	519_V	0.906	0.56
476_V	506_A	0.906	0.56
350_V	368_A	0.906	0.56
6_T	47_V	0.905	0.56
117_Q	273_I	0.905	0.56
96_N	100_A	0.904	0.56
188_E	214_A	0.901	0.56
111_A	248_A	0.900	0.56
241_A	246_V	0.900	0.56
474_A	506_A	0.899	0.56
306_V	312_A	0.897	0.55
99_A	129_K	0.896	0.55
7_D	290_A	0.894	0.55
188_E	192_A	0.892	0.55
219_M	244_D	0.890	0.55
502_V	506_A	0.888	0.55
159_D	181_G	0.884	0.54
165_L	182_A	0.881	0.54
479_A	489_G	0.876	0.54
330_A	364_V	0.876	0.54
147_L	172_I	0.874	0.53
509_E	512_G	0.874	0.53
183_E	189_T	0.874	0.53
157_R	161_L	0.873	0.53
117_Q	251_A	0.870	0.53
463_V	480_G	0.865	0.53
191_V	222_G	0.864	0.53
232_V	481_M	0.860	0.52
39_V	53_V	0.856	0.52
187_I	211_I	0.853	0.52
166_V	190_C	0.851	0.51
58_F	81_A	0.851	0.51
125_G	268_D	0.849	0.51
244_D	504_A	0.846	0.51
136_E	288_N	0.845	0.51
479_A	492_A	0.838	0.50
145_V	190_C	0.838	0.50
107_L	251_A	0.837	0.50
83_T	281_S	0.834	0.50
50_G	150_V	0.832	0.50
17_L	46_I	0.831	0.50
214_A	236_D	0.831	0.50
329_L	333_A	0.831	0.50
12_A	15_D	0.830	0.50
103_H	251_A	0.829	0.50
462_G	492_A	0.827	0.49
46_I	297_V	0.827	0.49
13_G	17_L	0.826	0.49
106_A	278_L	0.825	0.49
42_A	62_P	0.824	0.49
332_T	450_G	0.823	0.49
23_E	26_T	0.822	0.49
466_F	513_D	0.821	0.49
30_A	38_A	0.821	0.49
20_A	298_V	0.820	0.49
107_L	116_P	0.819	0.49
5_V	14_L	0.814	0.48
486_E	491_E	0.813	0.48
137_L	161_L	0.811	0.48
98_R	138_S	0.810	0.48
121_R	124_A	0.806	0.48
72_I	94_A	0.805	0.48
335_T	339_A	0.804	0.47
47_V	80_D	0.804	0.47
222_G	242_A	0.803	0.47
117_Q	132_Y	0.803	0.47
440_D	467_I	0.801	0.47
187_I	190_C	0.801	0.47
152_Q	182_A	0.800	0.47
6_T	28_Y	0.793	0.47
333_A	413_V	0.793	0.47
67_V	77_I	0.793	0.47
280_A	286_Q	0.792	0.46
87_V	395_A	0.792	0.46
142_L	198_T	0.792	0.46
47_V	83_T	0.791	0.46
328_D	331_E	0.789	0.46
137_L	196_F	0.788	0.46
117_Q	270_D	0.788	0.46
214_A	217_A	0.787	0.46
239_A	271_S	0.785	0.46
101_A	434_P	0.783	0.46
188_E	215_E	0.783	0.46
72_I	92_A	0.782	0.46
7_D	106_A	0.781	0.46
233_V	247_I	0.781	0.46
110_A	265_P	0.780	0.45
153_E	203_L	0.780	0.45
224_V	247_I	0.778	0.45
119_H	273_I	0.777	0.45
123_D	274_T	0.776	0.45
48_R	69_R	0.776	0.45
147_L	167_A	0.775	0.45
370_Q	374_A	0.774	0.45
459_D	477_N	0.773	0.45
39_V	61_A	0.771	0.45
278_L	281_S	0.770	0.45
467_I	494_T	0.768	0.44
500_A	510_L	0.767	0.44
230_G	259_P	0.765	0.44
484_A	489_G	0.763	0.44
468_G	472_G	0.761	0.44
66_I	90_A	0.761	0.44
100_A	105_V	0.760	0.44
53_V	110_A	0.758	0.44
129_K	303_G	0.758	0.44
39_V	45_L	0.758	0.44
396_V	469_G	0.756	0.43
47_V	281_S	0.756	0.43
9_I	160_S	0.755	0.43
58_F	62_P	0.754	0.43
156_T	162_G	0.752	0.43
444_V	473_T	0.748	0.43
267_H	274_T	0.747	0.43
367_A	507_L	0.746	0.43
355_E	409_S	0.746	0.43
99_A	147_L	0.745	0.42
117_Q	121_R	0.745	0.42
154_V	198_T	0.744	0.42
483_N	492_A	0.743	0.42
333_A	424_V	0.742	0.42
464_I	483_N	0.741	0.42
90_A	297_V	0.741	0.42
231_G	280_A	0.739	0.42
464_I	481_M	0.737	0.42
33_D	40_S	0.735	0.42
110_A	116_P	0.734	0.42
197_L	325_P	0.733	0.42
48_R	73_G	0.732	0.41
445_E	448_P	0.732	0.41
410_L	427_T	0.731	0.41
459_D	479_A	0.730	0.41
485_R	490_G	0.730	0.41
95_G	435_R	0.730	0.41
197_L	218_R	0.729	0.41
90_A	296_Q	0.729	0.41
39_V	57_V	0.729	0.41
435_R	479_A	0.728	0.41
9_I	287_E	0.728	0.41
477_N	499_D	0.727	0.41
175_D	251_A	0.726	0.41
105_V	160_S	0.726	0.41
121_R	131_D	0.726	0.41
95_G	288_N	0.724	0.41
100_A	129_K	0.723	0.41
213_E	246_V	0.723	0.41
337_A	340_L	0.723	0.41
90_A	308_N	0.721	0.41
456_R	518_D	0.719	0.40
103_H	108_A	0.719	0.40
56_A	59_E	0.718	0.40
289_V	457_N	0.717	0.40
107_L	201_V	0.717	0.40
68_A	440_D	0.715	0.40
96_N	229_R	0.714	0.40
4_L	82_A	0.714	0.40
261_P	267_H	0.713	0.40
66_I	300_A	0.712	0.40
107_L	273_I	0.711	0.40
238_L	247_I	0.711	0.40
37_D	60_A	0.708	0.39
4_L	42_A	0.708	0.39
13_G	16_R	0.707	0.39
264_S	267_H	0.706	0.39
77_I	121_R	0.705	0.39
123_D	270_D	0.704	0.39
144_V	154_V	0.704	0.39
99_A	156_T	0.704	0.39
100_A	255_F	0.703	0.39
182_A	233_V	0.703	0.39
55_D	345_I	0.702	0.39
445_E	494_T	0.701	0.39
197_L	247_I	0.700	0.39
119_H	274_T	0.699	0.39
380_V	388_V	0.699	0.39
144_V	201_V	0.698	0.39
457_N	481_M	0.698	0.39
348_V	415_V	0.696	0.38
90_A	306_V	0.696	0.38
66_I	303_G	0.696	0.38
174_E	184_L	0.690	0.38
505_R	509_E	0.687	0.38
92_A	292_D	0.686	0.38
236_D	506_A	0.685	0.38
337_A	341_F	0.684	0.38
271_S	473_T	0.683	0.37
90_A	303_G	0.679	0.37
368_A	372_A	0.676	0.37
375_G	392_R	0.675	0.37
328_D	332_T	0.673	0.37
73_G	254_V	0.672	0.37
65_V	495_V	0.672	0.37
494_T	515_R	0.671	0.36
29_D	38_A	0.670	0.36
123_D	510_L	0.670	0.36
16_R	296_Q	0.670	0.36
88_M	394_I	0.668	0.36
273_I	431_G	0.668	0.36
9_I	46_I	0.668	0.36
83_T	387_R	0.667	0.36
196_F	225_I	0.666	0.36
36_L	58_F	0.665	0.36
77_I	138_S	0.664	0.36
115_I	132_Y	0.662	0.36
17_L	129_K	0.661	0.36
100_A	106_A	0.661	0.36
260_L	263_A	0.661	0.36
491_E	517_V	0.660	0.36
349_D	399_T	0.658	0.35
236_D	263_A	0.658	0.35
237_A	432_D	0.658	0.35
129_K	446_A	0.658	0.35
296_Q	308_N	0.657	0.35
442_F	481_M	0.656	0.35
455_A	494_T	0.654	0.35
346_E	424_V	0.654	0.35
17_L	149_R	0.654	0.35
147_L	184_L	0.653	0.35
326_F	409_S	0.653	0.35
72_I	129_K	0.653	0.35
66_I	297_V	0.651	0.35
83_T	483_N	0.650	0.35
460_T	463_V	0.649	0.35
67_V	380_V	0.648	0.35
341_F	420_A	0.647	0.35
338_A	372_A	0.647	0.35
10_A	177_A	0.646	0.35
74_V	79_I	0.644	0.34
131_D	270_D	0.644	0.34
316_E	319_A	0.643	0.34
263_A	268_D	0.643	0.34
345_I	394_I	0.643	0.34
92_A	157_R	0.642	0.34
80_D	84_D	0.642	0.34
35_L	39_V	0.642	0.34
442_F	497_N	0.640	0.34
504_A	521_S	0.640	0.34
162_G	296_Q	0.640	0.34
275_T	289_V	0.640	0.34
336_V	340_L	0.639	0.34
30_A	42_A	0.639	0.34
101_A	153_E	0.636	0.34
348_V	413_V	0.635	0.34
299_A	307_V	0.635	0.34
453_L	502_V	0.633	0.34
323_I	437_V	0.633	0.34
15_D	18_R	0.632	0.33
300_A	366_A	0.631	0.33
333_A	355_E	0.631	0.33
387_R	409_S	0.629	0.33
74_V	381_N	0.629	0.33
451_H	501_D	0.627	0.33
112_A	223_Y	0.627	0.33
46_I	298_V	0.626	0.33
92_A	296_Q	0.625	0.33
448_P	463_V	0.625	0.33
192_A	343_P	0.623	0.33
145_V	187_I	0.623	0.33
28_Y	46_I	0.622	0.33
233_V	421_E	0.622	0.33
334_G	371_G	0.620	0.33
103_H	116_P	0.619	0.32
55_D	210_L	0.618	0.32
369_Q	389_A	0.618	0.32
145_V	210_L	0.617	0.32
225_I	249_G	0.617	0.32
3_V	334_G	0.616	0.32
466_F	473_T	0.616	0.32
165_L	248_A	0.616	0.32
144_V	456_R	0.616	0.32
5_V	42_A	0.614	0.32
333_A	446_A	0.613	0.32
222_G	245_G	0.613	0.32
95_G	231_G	0.612	0.32
103_H	326_F	0.612	0.32
116_P	251_A	0.612	0.32
471_L	506_A	0.611	0.32
5_V	24_V	0.610	0.32
9_I	178_A	0.609	0.32
221_G	242_A	0.608	0.32
278_L	463_V	0.608	0.32
16_R	295_D	0.608	0.32
428_L	437_V	0.607	0.32
233_V	250_A	0.606	0.31
10_A	14_L	0.606	0.31
333_A	426_G	0.606	0.31
66_I	301_L	0.606	0.31
111_A	225_I	0.605	0.31
238_L	252_L	0.605	0.31
405_E	429_F	0.604	0.31
53_V	57_V	0.604	0.31
103_H	278_L	0.603	0.31
11_D	517_V	0.603	0.31
166_V	194_A	0.600	0.31
82_A	107_L	0.600	0.31
300_A	304_D	0.599	0.31
26_T	476_V	0.598	0.31
312_A	366_A	0.598	0.31
215_E	219_M	0.598	0.31
411_V	516_I	0.597	0.31
77_I	315_A	0.597	0.31
376_L	392_R	0.597	0.31
191_V	210_L	0.596	0.31
99_A	153_E	0.595	0.31
70_A	73_G	0.595	0.31
11_D	26_T	0.595	0.31
152_Q	204_T	0.594	0.31
466_F	469_G	0.594	0.31
184_L	344_R	0.591	0.30
327_V	428_L	0.590	0.30
205_D	382_A	0.589	0.30
13_G	46_I	0.587	0.30
234_D	310_L	0.587	0.30
142_L	310_L	0.586	0.30
180_L	232_V	0.586	0.30
172_I	498_L	0.586	0.30
495_V	498_L	0.584	0.30
59_E	270_D	0.584	0.30
44_A	481_M	0.584	0.30
351_T	412_S	0.584	0.30
196_F	248_A	0.583	0.30
92_A	445_E	0.583	0.30
306_V	319_A	0.583	0.30
230_G	258_E	0.582	0.30
373_F	394_I	0.582	0.30
232_V	347_R	0.580	0.30
216_L	247_I	0.580	0.30
241_A	250_A	0.579	0.30
60_A	63_D	0.579	0.30
47_V	145_V	0.578	0.29
176_R	274_T	0.576	0.29
40_S	63_D	0.575	0.29
457_N	482_F	0.575	0.29
218_R	475_E	0.574	0.29
132_Y	271_S	0.573	0.29
171_Y	290_A	0.573	0.29
123_D	239_A	0.572	0.29
346_E	416_G	0.571	0.29
48_R	229_R	0.571	0.29
73_G	76_N	0.571	0.29
147_L	442_F	0.570	0.29
100_A	289_V	0.570	0.29
144_V	187_I	0.569	0.29
3_V	19_D	0.568	0.29
27_A	42_A	0.568	0.29
453_L	471_L	0.566	0.29
465_G	469_G	0.565	0.29
13_G	103_H	0.565	0.29
331_E	371_G	0.564	0.28
342_D	419_D	0.563	0.28
33_D	508_D	0.562	0.28
47_V	137_L	0.562	0.28
105_V	142_L	0.562	0.28
144_V	501_D	0.561	0.28
65_V	145_V	0.560	0.28
6_T	51_T	0.560	0.28
480_G	497_N	0.560	0.28
176_R	180_L	0.560	0.28
173_G	248_A	0.560	0.28
384_N	389_A	0.559	0.28
171_Y	337_A	0.559	0.28
137_L	210_L	0.559	0.28
158_L	273_I	0.558	0.28
479_A	497_N	0.557	0.28
377_E	388_V	0.557	0.28
23_E	475_E	0.556	0.28
3_V	424_V	0.555	0.28
242_A	419_D	0.553	0.28
174_E	217_A	0.553	0.28
99_A	300_A	0.553	0.28
114_S	117_Q	0.552	0.28
99_A	104_T	0.552	0.28
202_P	231_G	0.552	0.28
36_L	40_S	0.552	0.28
13_G	298_V	0.552	0.28
135_T	248_A	0.551	0.28
336_V	422_L	0.551	0.28
147_L	152_Q	0.551	0.28
115_I	251_A	0.551	0.28
319_A	360_D	0.550	0.28
365_T	398_E	0.549	0.27
17_L	100_A	0.549	0.27
66_I	88_M	0.549	0.27
261_P	264_S	0.548	0.27
396_V	475_E	0.548	0.27
108_A	519_V	0.547	0.27
99_A	290_A	0.546	0.27
72_I	153_E	0.546	0.27
335_T	374_A	0.546	0.27
143_G	467_I	0.546	0.27
201_V	210_L	0.545	0.27
48_R	280_A	0.545	0.27
240_D	469_G	0.545	0.27
34_A	38_A	0.543	0.27
345_I	444_V	0.543	0.27
41_D	62_P	0.543	0.27
5_V	98_R	0.543	0.27
191_V	216_L	0.542	0.27
288_N	296_Q	0.542	0.27
13_G	291_T	0.542	0.27
48_R	277_H	0.542	0.27
122_L	312_A	0.541	0.27
361_V	400_K	0.541	0.27
437_V	440_D	0.541	0.27
173_G	212_G	0.540	0.27
361_V	398_E	0.540	0.27
458_H	517_V	0.540	0.27
9_I	315_A	0.539	0.27
470_V	479_A	0.538	0.27
211_I	247_I	0.538	0.27
165_L	501_D	0.537	0.27
142_L	166_V	0.537	0.27
68_A	496_Y	0.536	0.27
218_R	222_G	0.536	0.27
147_L	305_P	0.536	0.27
109_F	160_S	0.536	0.27
406_A	410_L	0.535	0.27
69_R	229_R	0.535	0.27
459_D	485_R	0.535	0.27
189_T	192_A	0.535	0.27
250_A	269_A	0.535	0.27
157_R	445_E	0.533	0.26
462_G	477_N	0.533	0.26
164_D	509_E	0.532	0.26
152_Q	392_R	0.532	0.26
69_R	73_G	0.532	0.26
222_G	244_D	0.531	0.26
372_A	495_V	0.531	0.26
255_F	281_S	0.530	0.26
90_A	304_D	0.530	0.26
462_G	471_L	0.529	0.26
167_A	180_L	0.529	0.26
105_V	109_F	0.526	0.26
406_A	430_A	0.525	0.26
92_A	289_V	0.525	0.26
466_F	470_V	0.524	0.26
41_D	503_P	0.523	0.26
452_M	495_V	0.523	0.26
474_A	505_R	0.523	0.26
326_F	379_Q	0.523	0.26
502_V	505_R	0.522	0.26
97_V	100_A	0.521	0.26
142_L	182_A	0.521	0.26
326_F	384_N	0.519	0.25
341_F	417_N	0.518	0.25
103_H	494_T	0.518	0.25
100_A	227_V	0.518	0.25
363_L	422_L	0.518	0.25
7_D	66_I	0.518	0.25
250_A	383_V	0.518	0.25
133_L	293_T	0.517	0.25
456_R	502_V	0.517	0.25
349_D	416_G	0.517	0.25
44_A	301_L	0.517	0.25
48_R	70_A	0.516	0.25
385_A	389_A	0.516	0.25
238_L	272_I	0.516	0.25
407_Y	437_V	0.515	0.25
92_A	149_R	0.514	0.25
90_A	481_M	0.513	0.25
272_I	355_E	0.512	0.25
308_N	457_N	0.512	0.25
345_I	415_V	0.512	0.25
36_L	39_V	0.512	0.25
100_A	303_G	0.511	0.25
8_P	29_D	0.510	0.25
18_R	519_V	0.510	0.25
168_Y	247_I	0.510	0.25
141_T	510_L	0.509	0.25
121_R	174_E	0.509	0.25
194_A	512_G	0.509	0.25
19_D	476_V	0.508	0.25
85_H	419_D	0.508	0.25
118_A	167_A	0.508	0.25
184_L	440_D	0.507	0.25
197_L	223_Y	0.506	0.25
66_I	464_I	0.506	0.25
435_R	445_E	0.506	0.25
8_P	47_V	0.506	0.25
371_G	388_V	0.506	0.25
345_I	372_A	0.505	0.25
157_R	308_N	0.505	0.25
66_I	302_A	0.504	0.24
199_I	222_G	0.504	0.24
72_I	97_V	0.503	0.24
55_D	78_D	0.503	0.24
9_I	97_V	0.503	0.24
223_Y	251_A	0.502	0.24
291_T	428_L	0.502	0.24
444_V	485_R	0.502	0.24
228_A	231_G	0.501	0.24
13_G	360_D	0.501	0.24
3_V	505_R	0.501	0.24
85_H	413_V	0.501	0.24
15_D	206_E	0.500	0.24
350_V	387_R	0.500	0.24

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ygyA	4	0.9886	100	0.36	Contact Map
3k5pA	3	0.7324	100	0.568	Contact Map
1sc6A	4	0.7154	100	0.574	Contact Map
2g76A	2	0.5693	100	0.619	Contact Map
2d0iA	2	0.6129	100	0.639	Contact Map
1wwkA	2	0.5712	100	0.642	Contact Map
2w2kA	2	0.6015	100	0.645	Contact Map
3wwyA	4	0.592	100	0.646	Contact Map
2gcgA	2	0.592	100	0.646	Contact Map
4g2nA	3	0.5844	100	0.647	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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