Q9HMP9 - HALSA - GREMLIN Contacts

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Q9HMP9 - Helicase

UniProt:	Q9HMP9	Sequences: MQFFPKPSPYDNQRAAMDAIRDALDGGTNVLFEGACGTGKTLAALAPALSHAQAEDKTVVITTNVHQQMRQFVREAREIHATEPIRAVVFKGKGSMCHIDVDYEECQVLRDNTHELVDATRDKRQLEERQRALLDEAQDGDTEAADARQAVMDELEAVESELAALQDGNVCERYRQNLVGNTDEFYQWLYDDVRTPEDIYGYAEEAGFCGYELLKDGIEGVDLAVCNYHHLLDPGIRAQFFRWLGRDPEDVVVVFDEAHNIEDAARDHAAETLTEQTLDSALDELQDTSDQRAAAAERVLGAFRDALVETYEDALRPGGDGPADTKSAVESNWVDVPVANDDRRDDLTLAFLQSYTGPGITEDVTDALGLGEYLDGEYEDAYRNGDATTRRECHVLAAAEFVEAYVERGGEFGQYPTAAVRRDDRTEAVYGRAERYTCIPREVTTDLFDAVHASVLMSATLRPFDVIGDVLGLDDPVELAFGLQFPEDRRRTFAVDTEPLFSSNREDRATQQAVAGALRDAAAYTPGNCLFFFPSYAEAKRYHDLLADCDATRYLDEPGVAADDLREAFVADGDGALFTSLWGTLAEGVSFDGDDARTVAVVGVPYPHLDARTEAVQDAYAQAFADRDADQGLRSDRQDAGWRYAVEIPTVRKTRQAMGRVIRSPEDFGVRMLVDRRYTAASRTGMQKYSVNPTFPPSERAEMVDVDPEKLRFSLLNFYGDLGAYGGDPPAP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	732 (619)
Sequences:	2817 (2078)
Seq/√Len:	83.5

ECOLI - DING YOAA
BACSU - DING YPVA
HALSA - Q9HMP9 Q9HQ08 Q9HMM1
SULSO - Q980I2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
486_P	489_R	7.469	1.00
565_L	569_F	5.302	1.00
231_L	255_F	5.093	1.00
258_A	456_L	4.997	1.00
48_A	254_V	4.805	1.00
24_L	252_V	4.724	1.00
566_R	569_F	4.498	1.00
518_L	600_A	4.370	1.00
522_A	529_C	4.176	1.00
512_Q	545_L	4.135	1.00
528_N	597_R	4.054	1.00
525_T	529_C	3.996	1.00
533_F	578_F	3.960	1.00
11_D	15_A	3.806	1.00
16_A	32_F	3.769	1.00
621_A	639_D	3.722	1.00
567_E	571_A	3.383	1.00
167_D	172_E	3.308	1.00
673_L	678_Y	3.231	1.00
521_A	672_M	3.198	1.00
533_F	542_Y	3.197	1.00
468_G	478_E	3.167	1.00
19_A	479_L	3.111	1.00
23_A	30_V	3.084	1.00
88_V	221_V	2.939	1.00
48_A	59_V	2.919	1.00
528_N	552_T	2.912	1.00
76_A	87_A	2.886	1.00
555_L	575_G	2.840	1.00
536_Y	580_S	2.813	1.00
414_Q	418_A	2.769	1.00
198_D	203_A	2.753	1.00
566_R	570_V	2.611	1.00
22_D	26_G	2.604	1.00
12_N	481_F	2.512	1.00
161_E	165_L	2.483	1.00
415_Y	418_A	2.473	1.00
543_H	556_D	2.469	1.00
339_A	343_R	2.436	1.00
255_F	261_I	2.410	1.00
413_G	416_P	2.371	1.00
521_A	598_T	2.362	1.00
527_G	594_D	2.343	1.00
546_L	578_F	2.316	1.00
518_L	531_F	2.293	1.00
598_T	672_M	2.259	1.00
594_D	597_R	2.240	1.00
515_A	545_L	2.210	1.00
622_Q	641_G	2.203	1.00
586_A	657_A	2.202	1.00
28_T	477_V	2.189	1.00
16_A	457_M	2.180	1.00
547_A	559_G	2.179	1.00
661_V	669_G	2.159	1.00
688_K	696_P	2.140	1.00
619_A	622_Q	2.120	1.00
651_V	687_Q	2.103	1.00
31_L	468_G	2.100	1.00
539_A	578_F	2.087	1.00
416_P	419_A	2.085	1.00
415_Y	419_A	2.059	1.00
170_V	188_W	2.057	1.00
553_R	572_D	2.044	1.00
592_D	664_S	2.018	1.00
60_V	253_V	2.015	1.00
572_D	575_G	1.970	1.00
570_V	595_D	1.969	1.00
640_A	643_R	1.956	1.00
260_N	587_E	1.952	1.00
188_W	191_D	1.947	1.00
658_M	673_L	1.946	1.00
14_R	18_D	1.943	1.00
658_M	671_R	1.925	1.00
59_V	254_V	1.920	1.00
41_T	255_F	1.906	1.00
30_V	455_V	1.893	1.00
581_L	653_K	1.880	1.00
619_A	623_A	1.879	1.00
526_P	552_T	1.876	1.00
72_F	225_V	1.865	1.00
343_R	346_D	1.862	1.00
654_T	687_Q	1.810	1.00
536_Y	540_K	1.795	1.00
618_D	646_V	1.789	1.00
300_L	303_F	1.784	1.00
31_L	467_I	1.775	1.00
654_T	673_L	1.749	1.00
467_I	471_L	1.724	1.00
12_N	482_G	1.720	1.00
539_A	556_D	1.701	1.00
62_T	228_Y	1.669	1.00
340_N	343_R	1.646	1.00
6_K	9_P	1.640	1.00
16_A	20_I	1.627	1.00
490_R	662_I	1.618	1.00
23_A	28_T	1.607	1.00
53_Q	222_D	1.605	1.00
519_R	549_C	1.604	1.00
168_G	171_C	1.596	1.00
158_V	161_E	1.596	1.00
639_D	644_Y	1.584	1.00
10_Y	13_Q	1.582	1.00
90_F	224_A	1.581	1.00
308_V	312_E	1.579	1.00
522_A	576_A	1.572	1.00
412_F	415_Y	1.566	1.00
529_C	598_T	1.560	1.00
512_Q	516_G	1.541	1.00
90_F	218_I	1.532	1.00
60_V	250_D	1.522	1.00
168_G	172_E	1.520	0.99
534_P	603_G	1.518	0.99
31_L	471_L	1.509	0.99
543_H	547_A	1.497	0.99
44_A	457_M	1.496	0.99
110_R	113_T	1.494	0.99
515_A	546_L	1.493	0.99
456_L	467_I	1.491	0.99
112_N	115_E	1.491	0.99
8_S	665_P	1.482	0.99
263_D	649_P	1.482	0.99
311_Y	315_L	1.480	0.99
517_A	674_V	1.473	0.99
526_P	574_D	1.469	0.99
591_F	595_D	1.459	0.99
169_N	173_R	1.456	0.99
515_A	542_Y	1.450	0.99
262_E	470_V	1.446	0.99
76_A	225_V	1.445	0.99
620_Y	624_F	1.437	0.99
565_L	570_V	1.434	0.99
23_A	453_A	1.431	0.99
19_A	30_V	1.430	0.99
353_Q	356_T	1.428	0.99
502_S	505_R	1.426	0.99
170_V	179_V	1.425	0.99
660_R	663_R	1.414	0.99
262_E	467_I	1.407	0.99
300_L	311_Y	1.401	0.99
597_R	668_F	1.399	0.99
311_Y	314_A	1.397	0.99
63_T	69_M	1.395	0.99
554_Y	578_F	1.390	0.99
604_V	650_T	1.387	0.99
552_T	574_D	1.379	0.99
98_H	209_C	1.378	0.99
353_Q	357_G	1.377	0.99
651_V	690_S	1.372	0.99
19_A	22_D	1.369	0.99
416_P	420_V	1.368	0.99
24_L	455_V	1.368	0.99
303_F	318_G	1.359	0.99
685_G	689_Y	1.352	0.99
275_E	431_G	1.351	0.99
161_E	172_E	1.348	0.99
15_A	18_D	1.326	0.99
339_A	346_D	1.325	0.99
531_F	576_A	1.322	0.99
333_W	337_P	1.321	0.99
89_V	225_V	1.320	0.99
565_L	568_A	1.319	0.99
533_F	539_A	1.318	0.99
259_H	458_S	1.316	0.99
22_D	477_V	1.314	0.99
659_G	663_R	1.310	0.98
299_V	302_A	1.309	0.98
516_G	549_C	1.306	0.98
351_F	357_G	1.305	0.98
498_E	517_A	1.305	0.98
397_A	401_F	1.297	0.98
35_A	481_F	1.294	0.98
396_L	400_E	1.293	0.98
384_N	395_V	1.290	0.98
19_A	477_V	1.289	0.98
340_N	345_D	1.287	0.98
621_A	645_A	1.286	0.98
65_V	68_Q	1.286	0.98
525_T	598_T	1.284	0.98
536_Y	539_A	1.283	0.98
606_Y	683_R	1.279	0.98
63_T	67_Q	1.273	0.98
29_N	453_A	1.268	0.98
37_G	40_K	1.267	0.98
32_F	481_F	1.266	0.98
98_H	203_A	1.264	0.98
542_Y	578_F	1.263	0.98
531_F	578_F	1.261	0.98
384_N	387_A	1.260	0.98
564_D	567_E	1.260	0.98
20_I	47_P	1.257	0.98
555_L	572_D	1.257	0.98
606_Y	647_E	1.251	0.98
340_N	346_D	1.250	0.98
315_L	319_G	1.248	0.98
31_L	461_L	1.245	0.98
671_R	694_T	1.237	0.98
313_D	316_R	1.236	0.98
514_V	518_L	1.235	0.98
468_G	476_P	1.234	0.98
272_T	434_E	1.229	0.98
464_F	478_E	1.228	0.98
618_D	622_Q	1.222	0.98
190_Y	193_V	1.213	0.97
354_S	357_G	1.210	0.97
656_Q	659_G	1.209	0.97
412_F	416_P	1.207	0.97
491_R	694_T	1.205	0.97
641_G	644_Y	1.203	0.97
643_R	682_S	1.202	0.97
493_F	673_L	1.202	0.97
86_R	217_G	1.201	0.97
109_L	113_T	1.200	0.97
106_C	109_L	1.190	0.97
314_A	318_G	1.189	0.97
394_H	401_F	1.185	0.97
68_Q	71_Q	1.184	0.97
166_Q	171_C	1.175	0.97
161_E	168_G	1.173	0.97
339_A	342_D	1.168	0.97
332_N	335_D	1.163	0.97
216_D	219_E	1.161	0.97
399_A	403_E	1.161	0.97
312_E	315_L	1.159	0.97
161_E	167_D	1.155	0.97
528_N	573_G	1.153	0.97
541_R	545_L	1.149	0.97
121_R	124_R	1.140	0.96
49_L	85_I	1.136	0.96
462_R	480_A	1.129	0.96
97_C	102_D	1.128	0.96
392_E	396_L	1.127	0.96
556_D	559_G	1.125	0.96
249_E	450_A	1.125	0.96
330_E	334_V	1.125	0.96
100_D	204_E	1.119	0.96
344_R	348_T	1.119	0.96
663_R	667_D	1.108	0.96
173_R	177_N	1.107	0.96
362_E	365_T	1.102	0.96
564_D	568_A	1.101	0.96
10_Y	34_G	1.101	0.96
232_L	261_I	1.100	0.96
520_D	523_A	1.093	0.95
266_R	436_Y	1.092	0.95
563_D	567_E	1.090	0.95
540_K	544_D	1.086	0.95
187_Q	190_Y	1.084	0.95
391_R	394_H	1.083	0.95
35_A	484_Q	1.082	0.95
622_Q	640_A	1.080	0.95
199_I	204_E	1.079	0.95
336_V	339_A	1.079	0.95
118_D	121_R	1.077	0.95
162_L	165_L	1.076	0.95
444_T	448_F	1.073	0.95
600_A	674_V	1.070	0.95
23_A	27_G	1.067	0.95
504_N	507_D	1.065	0.95
114_H	119_A	1.064	0.95
351_F	356_T	1.061	0.95
41_T	587_E	1.058	0.94
253_V	454_S	1.057	0.94
99_I	210_G	1.055	0.94
17_M	20_I	1.049	0.94
203_A	209_C	1.045	0.94
272_T	432_R	1.042	0.94
72_F	87_A	1.042	0.94
556_D	578_F	1.041	0.94
88_V	214_L	1.038	0.94
168_G	177_N	1.037	0.94
64_N	260_N	1.037	0.94
88_V	224_A	1.037	0.94
68_Q	93_K	1.034	0.94
42_L	603_G	1.033	0.94
451_V	454_S	1.033	0.94
445_T	449_D	1.031	0.94
169_N	172_E	1.025	0.93
352_L	355_Y	1.024	0.93
113_T	116_L	1.018	0.93
412_F	417_T	1.012	0.93
658_M	694_T	1.011	0.93
614_E	646_V	1.009	0.93
168_G	173_R	1.007	0.93
188_W	198_D	1.006	0.93
378_Y	382_Y	1.005	0.93
542_Y	545_L	1.004	0.93
565_L	577_L	1.002	0.93
17_M	21_R	1.002	0.93
266_R	617_Q	1.000	0.93
35_A	483_L	0.999	0.93
336_V	340_N	0.997	0.92
121_R	125_Q	0.997	0.92
63_T	227_N	0.994	0.92
226_C	231_L	0.985	0.92
170_V	177_N	0.982	0.92
384_N	390_R	0.979	0.92
601_V	654_T	0.976	0.92
514_V	674_V	0.974	0.92
601_V	658_M	0.971	0.91
264_A	267_D	0.971	0.91
510_T	514_V	0.969	0.91
49_L	223_L	0.967	0.91
396_L	401_F	0.962	0.91
176_Q	179_V	0.961	0.91
170_V	176_Q	0.961	0.91
65_V	93_K	0.954	0.91
334_V	337_P	0.951	0.91
395_V	399_A	0.951	0.91
108_V	112_N	0.950	0.91
105_E	109_L	0.948	0.90
35_A	487_E	0.947	0.90
193_V	199_I	0.944	0.90
234_P	248_P	0.942	0.90
341_D	344_R	0.941	0.90
411_E	415_Y	0.941	0.90
165_L	168_G	0.940	0.90
395_V	402_V	0.939	0.90
303_F	310_T	0.937	0.90
414_Q	421_R	0.931	0.90
105_E	108_V	0.930	0.90
656_Q	660_R	0.928	0.90
458_S	472_G	0.928	0.90
332_N	339_A	0.926	0.89
345_D	348_T	0.925	0.89
172_E	177_N	0.924	0.89
34_G	227_N	0.921	0.89
379_E	383_R	0.920	0.89
81_A	84_P	0.920	0.89
63_T	68_Q	0.919	0.89
254_V	465_D	0.917	0.89
333_W	336_V	0.916	0.89
64_N	67_Q	0.914	0.89
330_E	333_W	0.913	0.89
390_R	402_V	0.912	0.89
487_E	662_I	0.912	0.89
486_P	490_R	0.911	0.89
304_R	310_T	0.910	0.89
57_K	251_V	0.910	0.89
332_N	336_V	0.909	0.89
538_E	602_V	0.905	0.88
400_E	403_E	0.905	0.88
396_L	402_V	0.903	0.88
402_V	408_R	0.903	0.88
530_L	599_V	0.903	0.88
232_L	265_A	0.901	0.88
114_H	117_V	0.900	0.88
378_Y	381_A	0.896	0.88
681_A	684_T	0.895	0.88
590_S	669_G	0.895	0.88
573_G	594_D	0.894	0.88
505_R	509_A	0.889	0.87
331_S	334_V	0.887	0.87
384_N	402_V	0.882	0.87
93_K	211_Y	0.882	0.87
481_F	592_D	0.881	0.87
330_E	338_V	0.880	0.87
350_A	354_S	0.878	0.87
504_N	676_R	0.876	0.87
193_V	197_E	0.875	0.87
656_Q	663_R	0.872	0.86
93_K	234_P	0.872	0.86
26_G	477_V	0.871	0.86
301_G	305_D	0.871	0.86
337_P	341_D	0.871	0.86
66_H	71_Q	0.870	0.86
342_D	345_D	0.865	0.86
528_N	591_F	0.865	0.86
109_L	117_V	0.863	0.86
464_F	472_G	0.863	0.86
229_H	268_H	0.862	0.86
248_P	464_F	0.860	0.86
308_V	318_G	0.859	0.86
165_L	172_E	0.858	0.86
191_D	198_D	0.856	0.85
44_A	228_Y	0.852	0.85
11_D	14_R	0.849	0.85
528_N	598_T	0.849	0.85
113_T	117_V	0.848	0.85
492_T	670_V	0.848	0.85
660_R	669_G	0.847	0.85
663_R	669_G	0.845	0.85
402_V	405_Y	0.845	0.85
377_E	380_D	0.844	0.85
165_L	169_N	0.844	0.85
336_V	341_D	0.844	0.85
552_T	576_A	0.844	0.85
257_E	660_R	0.843	0.84
50_S	528_N	0.841	0.84
332_N	338_V	0.836	0.84
545_L	549_C	0.836	0.84
374_L	409_G	0.834	0.84
498_E	513_A	0.834	0.84
614_E	645_A	0.833	0.84
523_A	551_A	0.831	0.84
388_T	391_R	0.831	0.84
614_E	618_D	0.830	0.84
36_C	65_V	0.823	0.83
91_K	98_H	0.821	0.83
511_Q	514_V	0.821	0.83
31_L	464_F	0.820	0.83
350_A	353_Q	0.816	0.83
538_E	542_Y	0.816	0.83
458_S	590_S	0.816	0.83
38_T	464_F	0.815	0.82
337_P	344_R	0.814	0.82
42_L	479_L	0.814	0.82
399_A	402_V	0.814	0.82
297_E	301_G	0.811	0.82
17_M	42_L	0.809	0.82
257_E	659_G	0.807	0.82
346_D	349_L	0.807	0.82
650_T	669_G	0.806	0.82
252_V	453_A	0.803	0.82
158_V	165_L	0.802	0.81
386_D	390_R	0.800	0.81
657_A	669_G	0.799	0.81
652_R	662_I	0.798	0.81
86_R	222_D	0.797	0.81
566_R	595_D	0.796	0.81
71_Q	77_R	0.796	0.81
485_F	490_R	0.794	0.81
537_A	541_R	0.792	0.81
120_T	124_R	0.792	0.81
447_L	451_V	0.790	0.80
530_L	575_G	0.790	0.80
51_H	252_V	0.789	0.80
339_A	345_D	0.788	0.80
231_L	253_V	0.788	0.80
393_C	396_L	0.787	0.80
344_R	347_L	0.787	0.80
570_V	594_D	0.786	0.80
166_Q	172_E	0.785	0.80
544_D	548_D	0.785	0.80
31_L	649_P	0.785	0.80
98_H	198_D	0.784	0.80
648_I	686_M	0.784	0.80
21_R	25_D	0.783	0.80
303_F	311_Y	0.783	0.80
97_C	223_L	0.781	0.80
210_G	586_A	0.780	0.80
530_L	591_F	0.780	0.80
415_Y	420_V	0.779	0.80
174_Y	177_N	0.777	0.79
568_A	571_A	0.777	0.79
73_V	285_L	0.776	0.79
339_A	344_R	0.776	0.79
311_Y	317_P	0.775	0.79
553_R	575_G	0.775	0.79
38_T	690_S	0.775	0.79
569_F	595_D	0.774	0.79
673_L	691_V	0.774	0.79
394_H	397_A	0.774	0.79
297_E	300_L	0.774	0.79
376_G	571_A	0.772	0.79
69_M	268_H	0.772	0.79
395_V	398_A	0.770	0.79
87_A	223_L	0.770	0.79
20_I	32_F	0.768	0.79
302_A	305_D	0.767	0.78
349_L	352_L	0.766	0.78
77_R	198_D	0.765	0.78
555_L	568_A	0.765	0.78
336_V	342_D	0.764	0.78
550_D	553_R	0.762	0.78
59_V	71_Q	0.760	0.78
65_V	578_F	0.756	0.77
366_D	369_G	0.754	0.77
512_Q	541_R	0.754	0.77
561_A	564_D	0.753	0.77
97_C	273_L	0.752	0.77
10_Y	16_A	0.752	0.77
106_C	110_R	0.751	0.77
228_Y	532_F	0.751	0.77
113_T	120_T	0.750	0.77
75_E	437_T	0.749	0.77
521_A	600_A	0.748	0.77
676_R	680_A	0.748	0.77
188_W	193_V	0.746	0.77
264_A	536_Y	0.745	0.76
530_L	657_A	0.745	0.76
171_C	174_Y	0.745	0.76
20_I	23_A	0.743	0.76
588_G	659_G	0.743	0.76
99_I	208_F	0.742	0.76
311_Y	318_G	0.742	0.76
110_R	114_H	0.740	0.76
117_V	120_T	0.740	0.76
393_C	400_E	0.740	0.76
460_T	588_G	0.739	0.76
541_R	544_D	0.739	0.76
187_Q	191_D	0.738	0.76
171_C	177_N	0.737	0.76
621_A	644_Y	0.736	0.76
92_G	485_F	0.736	0.76
97_C	278_L	0.736	0.76
170_V	674_V	0.735	0.75
119_A	122_D	0.734	0.75
91_K	661_V	0.733	0.75
589_V	614_E	0.732	0.75
262_E	265_A	0.731	0.75
36_C	227_N	0.731	0.75
102_D	162_L	0.730	0.75
553_R	573_G	0.728	0.75
351_F	355_Y	0.728	0.75
64_N	687_Q	0.727	0.75
61_I	228_Y	0.722	0.74
367_A	370_L	0.720	0.74
372_E	376_G	0.719	0.74
41_T	284_E	0.719	0.74
621_A	624_F	0.718	0.74
687_Q	690_S	0.718	0.74
465_D	469_D	0.717	0.74
508_R	512_Q	0.713	0.73
393_C	398_A	0.712	0.73
86_R	221_V	0.710	0.73
286_Q	308_V	0.710	0.73
464_F	467_I	0.710	0.73
488_D	693_P	0.707	0.73
590_S	650_T	0.707	0.73
308_V	314_A	0.706	0.72
64_N	68_Q	0.706	0.72
99_I	102_D	0.704	0.72
367_A	373_Y	0.704	0.72
515_A	519_R	0.703	0.72
369_G	372_E	0.702	0.72
441_R	456_L	0.702	0.72
338_V	345_D	0.701	0.72
458_S	669_G	0.701	0.72
398_A	402_V	0.698	0.72
392_E	395_V	0.697	0.72
122_D	455_V	0.697	0.72
409_G	412_F	0.697	0.72
115_E	119_A	0.696	0.71
660_R	667_D	0.695	0.71
65_V	605_P	0.693	0.71
385_G	404_A	0.693	0.71
300_L	314_A	0.693	0.71
66_H	95_S	0.693	0.71
255_F	456_L	0.693	0.71
46_A	51_H	0.692	0.71
643_R	647_E	0.690	0.71
341_D	345_D	0.690	0.71
212_E	528_N	0.690	0.71
75_E	78_E	0.689	0.71
506_E	541_R	0.688	0.71
317_P	320_D	0.687	0.70
6_K	488_D	0.687	0.70
460_T	663_R	0.687	0.70
306_A	311_Y	0.686	0.70
580_S	586_A	0.685	0.70
527_G	591_F	0.685	0.70
211_Y	232_L	0.684	0.70
507_D	512_Q	0.683	0.70
85_I	222_D	0.683	0.70
376_G	379_E	0.682	0.70
47_P	50_S	0.681	0.70
525_T	597_R	0.679	0.70
410_G	415_Y	0.678	0.69
621_A	625_A	0.678	0.69
491_R	658_M	0.678	0.69
554_Y	560_V	0.678	0.69
625_A	642_W	0.677	0.69
248_P	593_G	0.676	0.69
342_D	346_D	0.676	0.69
116_L	355_Y	0.675	0.69
527_G	569_F	0.675	0.69
378_Y	384_N	0.674	0.69
497_T	699_E	0.673	0.69
21_R	54_A	0.671	0.69
257_E	656_Q	0.671	0.69
354_S	358_P	0.670	0.69
651_V	654_T	0.670	0.69
642_W	684_T	0.670	0.69
527_G	574_D	0.668	0.68
23_A	455_V	0.668	0.68
171_C	176_Q	0.667	0.68
577_L	585_L	0.667	0.68
311_Y	316_R	0.667	0.68
603_G	678_Y	0.667	0.68
191_D	194_R	0.666	0.68
509_A	554_Y	0.666	0.68
458_S	530_L	0.665	0.68
85_I	223_L	0.664	0.68
528_N	668_F	0.663	0.68
49_L	76_A	0.663	0.68
333_W	342_D	0.663	0.68
553_R	568_A	0.662	0.68
257_E	588_G	0.661	0.67
521_A	674_V	0.661	0.67
239_Q	245_G	0.660	0.67
380_D	384_N	0.660	0.67
365_T	372_E	0.658	0.67
13_Q	39_G	0.658	0.67
159_E	163_A	0.658	0.67
170_V	175_R	0.657	0.67
586_A	655_R	0.656	0.67
257_E	663_R	0.655	0.67
516_G	520_D	0.654	0.67
346_D	350_A	0.654	0.67
213_L	217_G	0.653	0.67
108_V	111_D	0.652	0.66
316_R	696_P	0.652	0.66
378_Y	389_T	0.652	0.66
466_V	470_V	0.651	0.66
69_M	73_V	0.650	0.66
389_T	392_E	0.649	0.66
265_A	437_T	0.649	0.66
20_I	457_M	0.648	0.66
116_L	119_A	0.647	0.66
50_S	230_H	0.647	0.66
373_Y	377_E	0.646	0.66
230_H	234_P	0.646	0.66
511_Q	545_L	0.645	0.66
98_H	210_G	0.645	0.66
328_A	334_V	0.645	0.66
9_P	14_R	0.644	0.65
35_A	44_A	0.644	0.65
232_L	435_R	0.643	0.65
375_D	378_Y	0.642	0.65
460_T	659_G	0.642	0.65
231_L	539_A	0.642	0.65
467_I	470_V	0.641	0.65
34_G	44_A	0.641	0.65
118_D	122_D	0.641	0.65
318_G	321_G	0.641	0.65
30_V	477_V	0.640	0.65
306_A	363_D	0.640	0.65
526_P	668_F	0.640	0.65
596_A	661_V	0.640	0.65
588_G	660_R	0.639	0.65
200_Y	599_V	0.639	0.65
305_D	309_E	0.639	0.65
21_R	50_S	0.639	0.65
42_L	456_L	0.637	0.65
117_V	121_R	0.637	0.65
311_Y	319_G	0.637	0.65
624_F	639_D	0.637	0.65
194_R	671_R	0.637	0.65
659_G	669_G	0.636	0.65
393_C	401_F	0.636	0.65
13_Q	40_K	0.635	0.64
59_V	223_L	0.634	0.64
69_M	538_E	0.634	0.64
300_L	307_L	0.633	0.64
417_T	420_V	0.633	0.64
90_F	230_H	0.632	0.64
411_E	414_Q	0.631	0.64
44_A	61_I	0.629	0.64
330_E	335_D	0.629	0.64
66_H	69_M	0.629	0.64
368_L	512_Q	0.628	0.64
413_G	417_T	0.628	0.64
229_H	436_Y	0.627	0.63
43_A	625_A	0.627	0.63
495_V	679_T	0.627	0.63
397_A	409_G	0.626	0.63
440_P	463_P	0.626	0.63
201_G	276_Q	0.625	0.63
74_R	88_V	0.624	0.63
379_E	382_Y	0.624	0.63
18_D	22_D	0.624	0.63
519_R	546_L	0.624	0.63
334_V	341_D	0.622	0.63
588_G	663_R	0.622	0.63
310_T	313_D	0.621	0.63
227_N	593_G	0.621	0.63
463_P	574_D	0.621	0.63
557_E	603_G	0.621	0.63
308_V	311_Y	0.620	0.63
302_A	311_Y	0.620	0.63
17_M	597_R	0.619	0.62
602_V	674_V	0.619	0.62
76_A	478_E	0.619	0.62
534_P	586_A	0.618	0.62
45_L	657_A	0.617	0.62
470_V	617_Q	0.615	0.62
114_H	223_L	0.615	0.62
116_L	397_A	0.615	0.62
306_A	315_L	0.615	0.62
91_K	227_N	0.614	0.62
331_S	339_A	0.613	0.62
360_I	364_V	0.612	0.62
384_N	389_T	0.611	0.61
381_A	384_N	0.611	0.61
338_V	344_R	0.611	0.61
288_T	295_A	0.611	0.61
336_V	345_D	0.610	0.61
331_S	343_R	0.610	0.61
439_I	610_D	0.609	0.61
187_Q	193_V	0.609	0.61
392_E	403_E	0.609	0.61
106_C	111_D	0.608	0.61
370_L	374_L	0.607	0.61
383_R	387_A	0.607	0.61
61_I	72_F	0.606	0.61
95_S	274_T	0.605	0.61
160_S	165_L	0.605	0.61
511_Q	515_A	0.605	0.61
365_T	368_L	0.604	0.61
525_T	670_V	0.604	0.61
530_L	592_D	0.604	0.61
377_E	381_A	0.603	0.60
116_L	301_G	0.603	0.60
331_S	336_V	0.603	0.60
683_R	692_N	0.602	0.60
405_Y	409_G	0.602	0.60
117_V	123_K	0.601	0.60
228_Y	234_P	0.601	0.60
114_H	118_D	0.601	0.60
13_Q	37_G	0.599	0.60
393_C	397_A	0.599	0.60
97_C	165_L	0.599	0.60
369_G	373_Y	0.598	0.60
194_R	197_E	0.597	0.60
328_A	336_V	0.597	0.60
510_T	645_A	0.597	0.60
616_V	619_A	0.597	0.60
343_R	619_A	0.597	0.60
394_H	402_V	0.596	0.60
16_A	43_A	0.596	0.60
343_R	347_L	0.595	0.59
211_Y	215_K	0.593	0.59
115_E	118_D	0.592	0.59
360_I	370_L	0.590	0.59
236_I	269_A	0.590	0.59
170_V	647_E	0.588	0.59
306_A	317_P	0.588	0.59
303_F	306_A	0.587	0.58
341_D	347_L	0.587	0.58
42_L	46_A	0.586	0.58
110_R	116_L	0.586	0.58
166_Q	169_N	0.586	0.58
518_L	522_A	0.586	0.58
304_R	314_A	0.586	0.58
101_V	416_P	0.585	0.58
588_G	656_Q	0.585	0.58
408_R	411_E	0.584	0.58
316_R	319_G	0.583	0.58
290_D	535_S	0.583	0.58
684_T	692_N	0.583	0.58
168_G	174_Y	0.582	0.58
300_L	317_P	0.582	0.58
652_R	655_R	0.581	0.58
381_A	390_R	0.581	0.58
659_G	667_D	0.581	0.58
332_N	344_R	0.580	0.57
277_T	280_S	0.580	0.57
75_E	200_Y	0.580	0.57
511_Q	542_Y	0.580	0.57
522_A	525_T	0.579	0.57
262_E	579_T	0.579	0.57
43_A	52_A	0.578	0.57
46_A	79_I	0.578	0.57
274_T	277_T	0.578	0.57
334_V	340_N	0.577	0.57
48_A	616_V	0.577	0.57
193_V	196_P	0.577	0.57
91_K	169_N	0.576	0.57
40_K	588_G	0.575	0.57
257_E	460_T	0.575	0.57
64_N	264_A	0.574	0.57
64_N	93_K	0.574	0.57
227_N	485_F	0.573	0.57
122_D	125_Q	0.572	0.56
36_C	438_C	0.572	0.56
29_N	32_F	0.571	0.56
393_C	402_V	0.570	0.56
460_T	660_R	0.569	0.56
234_P	268_H	0.569	0.56
118_D	403_E	0.568	0.56
299_V	313_D	0.567	0.56
109_L	112_N	0.567	0.56
360_I	369_G	0.567	0.56
190_Y	515_A	0.566	0.56
187_Q	198_D	0.566	0.56
494_A	672_M	0.566	0.56
304_R	307_L	0.565	0.56
528_N	574_D	0.564	0.55
15_A	479_L	0.564	0.55
527_G	597_R	0.564	0.55
511_Q	541_R	0.563	0.55
369_G	375_D	0.563	0.55
20_I	252_V	0.563	0.55
192_D	198_D	0.562	0.55
560_V	577_L	0.561	0.55
598_T	670_V	0.560	0.55
43_A	47_P	0.560	0.55
265_A	585_L	0.560	0.55
113_T	119_A	0.558	0.55
38_T	211_Y	0.558	0.55
651_V	655_R	0.558	0.55
70_R	612_R	0.558	0.55
48_A	600_A	0.557	0.54
407_E	410_G	0.557	0.54
296_A	300_L	0.557	0.54
193_V	673_L	0.557	0.54
17_M	47_P	0.556	0.54
230_H	233_D	0.556	0.54
350_A	358_P	0.556	0.54
522_A	552_T	0.556	0.54
91_K	95_S	0.556	0.54
292_R	295_A	0.555	0.54
482_G	693_P	0.554	0.54
34_G	38_T	0.553	0.54
436_Y	613_T	0.553	0.54
591_F	597_R	0.553	0.54
93_K	232_L	0.552	0.54
485_F	593_G	0.552	0.54
309_E	410_G	0.552	0.54
524_Y	668_F	0.551	0.54
655_R	687_Q	0.551	0.54
160_S	166_Q	0.551	0.54
589_V	662_I	0.550	0.54
45_L	79_I	0.550	0.54
161_E	164_A	0.549	0.53
300_L	315_L	0.548	0.53
579_T	694_T	0.547	0.53
654_T	691_V	0.547	0.53
441_R	599_V	0.546	0.53
295_A	387_A	0.545	0.53
161_E	169_N	0.545	0.53
548_D	551_A	0.545	0.53
57_K	673_L	0.544	0.53
310_T	319_G	0.544	0.53
91_K	96_M	0.543	0.53
329_V	333_W	0.543	0.53
404_A	410_G	0.543	0.53
313_D	317_P	0.543	0.53
441_R	472_G	0.542	0.52
10_Y	44_A	0.542	0.52
49_L	280_S	0.542	0.52
543_H	559_G	0.542	0.52
115_E	120_T	0.541	0.52
651_V	686_M	0.541	0.52
302_A	306_A	0.540	0.52
80_H	85_I	0.540	0.52
383_R	389_T	0.540	0.52
6_K	13_Q	0.540	0.52
36_C	39_G	0.539	0.52
498_E	673_L	0.539	0.52
109_L	114_H	0.539	0.52
536_Y	596_A	0.539	0.52
33_E	480_A	0.538	0.52
514_V	602_V	0.538	0.52
188_W	194_R	0.538	0.52
33_E	655_R	0.538	0.52
256_D	656_Q	0.538	0.52
10_Y	532_F	0.537	0.52
44_A	225_V	0.537	0.52
236_I	239_Q	0.537	0.52
543_H	578_F	0.535	0.52
229_H	264_A	0.535	0.52
206_A	212_E	0.533	0.51
24_L	453_A	0.532	0.51
116_L	123_K	0.532	0.51
466_V	648_I	0.531	0.51
532_F	661_V	0.530	0.51
61_I	442_E	0.530	0.51
105_E	112_N	0.530	0.51
41_T	71_Q	0.529	0.51
108_V	118_D	0.528	0.51
593_G	664_S	0.527	0.51
365_T	409_G	0.527	0.51
650_T	683_R	0.527	0.51
477_V	518_L	0.527	0.51
273_L	350_A	0.527	0.51
90_F	653_K	0.527	0.51
552_T	597_R	0.526	0.50
299_V	304_R	0.526	0.50
481_F	651_V	0.526	0.50
537_A	540_K	0.525	0.50
414_Q	420_V	0.525	0.50
96_M	532_F	0.525	0.50
352_L	357_G	0.524	0.50
309_E	312_E	0.524	0.50
18_D	24_L	0.523	0.50
277_T	397_A	0.522	0.50
528_N	596_A	0.522	0.50
278_L	285_L	0.522	0.50
65_V	75_E	0.522	0.50
286_Q	445_T	0.522	0.50
387_A	398_A	0.522	0.50
349_L	354_S	0.521	0.50
303_F	316_R	0.521	0.50
161_E	171_C	0.520	0.50
63_T	66_H	0.519	0.49
36_C	40_K	0.518	0.49
10_Y	661_V	0.518	0.49
79_I	93_K	0.518	0.49
642_W	683_R	0.518	0.49
92_G	230_H	0.518	0.49
306_A	319_G	0.517	0.49
59_V	68_Q	0.517	0.49
480_A	655_R	0.516	0.49
98_H	532_F	0.516	0.49
170_V	360_I	0.516	0.49
394_H	400_E	0.515	0.49
307_L	321_G	0.514	0.49
198_D	209_C	0.514	0.49
377_E	384_N	0.514	0.49
591_F	664_S	0.514	0.49
32_F	457_M	0.513	0.49
92_G	227_N	0.512	0.49
339_A	601_V	0.512	0.49
202_Y	578_F	0.512	0.49
266_R	270_A	0.511	0.48
205_E	208_F	0.510	0.48
17_M	32_F	0.510	0.48
48_A	352_L	0.510	0.48
378_Y	395_V	0.509	0.48
37_G	41_T	0.508	0.48
110_R	117_V	0.508	0.48
267_D	319_G	0.508	0.48
265_A	648_I	0.508	0.48
66_H	596_A	0.508	0.48
44_A	459_A	0.506	0.48
296_A	299_V	0.506	0.48
482_G	590_S	0.506	0.48
278_L	311_Y	0.506	0.48
383_R	402_V	0.505	0.48
437_T	458_S	0.505	0.48
228_Y	487_E	0.505	0.48
10_Y	596_A	0.504	0.47
658_M	691_V	0.504	0.47
508_R	516_G	0.504	0.47
554_Y	567_E	0.502	0.47
109_L	116_L	0.501	0.47
74_R	96_M	0.500	0.47

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4a15A	1	0.8005	100	0.364	Contact Map
3crvA	1	0.7391	100	0.417	Contact Map
2vl7A	1	0.623	100	0.457	Contact Map
1gkuB	1	0.5574	100	0.789	Contact Map
3fhoA	2	0.4098	100	0.812	Contact Map
4ys0A	1	0.7582	100	0.814	Contact Map
4dduA	1	0.5683	100	0.816	Contact Map
4w7sA	2	0.5164	100	0.83	Contact Map
3oiyA	1	0.5232	100	0.83	Contact Map
2ykgA	1	0.6585	100	0.834	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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