GREMLIN Database
Q9HMP9 - Helicase
UniProt: Q9HMP9 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 732 (619)
Sequences: 2817 (2078)
Seq/√Len: 83.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
486_P489_R7.4691.00
565_L569_F5.3021.00
231_L255_F5.0931.00
258_A456_L4.9971.00
48_A254_V4.8051.00
24_L252_V4.7241.00
566_R569_F4.4981.00
518_L600_A4.3701.00
522_A529_C4.1761.00
512_Q545_L4.1351.00
528_N597_R4.0541.00
525_T529_C3.9961.00
533_F578_F3.9601.00
11_D15_A3.8061.00
16_A32_F3.7691.00
621_A639_D3.7221.00
567_E571_A3.3831.00
167_D172_E3.3081.00
673_L678_Y3.2311.00
521_A672_M3.1981.00
533_F542_Y3.1971.00
468_G478_E3.1671.00
19_A479_L3.1111.00
23_A30_V3.0841.00
88_V221_V2.9391.00
48_A59_V2.9191.00
528_N552_T2.9121.00
76_A87_A2.8861.00
555_L575_G2.8401.00
536_Y580_S2.8131.00
414_Q418_A2.7691.00
198_D203_A2.7531.00
566_R570_V2.6111.00
22_D26_G2.6041.00
12_N481_F2.5121.00
161_E165_L2.4831.00
415_Y418_A2.4731.00
543_H556_D2.4691.00
339_A343_R2.4361.00
255_F261_I2.4101.00
413_G416_P2.3711.00
521_A598_T2.3621.00
527_G594_D2.3431.00
546_L578_F2.3161.00
518_L531_F2.2931.00
598_T672_M2.2591.00
594_D597_R2.2401.00
515_A545_L2.2101.00
622_Q641_G2.2031.00
586_A657_A2.2021.00
28_T477_V2.1891.00
16_A457_M2.1801.00
547_A559_G2.1791.00
661_V669_G2.1591.00
688_K696_P2.1401.00
619_A622_Q2.1201.00
651_V687_Q2.1031.00
31_L468_G2.1001.00
539_A578_F2.0871.00
416_P419_A2.0851.00
415_Y419_A2.0591.00
170_V188_W2.0571.00
553_R572_D2.0441.00
592_D664_S2.0181.00
60_V253_V2.0151.00
572_D575_G1.9701.00
570_V595_D1.9691.00
640_A643_R1.9561.00
260_N587_E1.9521.00
188_W191_D1.9471.00
658_M673_L1.9461.00
14_R18_D1.9431.00
658_M671_R1.9251.00
59_V254_V1.9201.00
41_T255_F1.9061.00
30_V455_V1.8931.00
581_L653_K1.8801.00
619_A623_A1.8791.00
526_P552_T1.8761.00
72_F225_V1.8651.00
343_R346_D1.8621.00
654_T687_Q1.8101.00
536_Y540_K1.7951.00
618_D646_V1.7891.00
300_L303_F1.7841.00
31_L467_I1.7751.00
654_T673_L1.7491.00
467_I471_L1.7241.00
12_N482_G1.7201.00
539_A556_D1.7011.00
62_T228_Y1.6691.00
340_N343_R1.6461.00
6_K9_P1.6401.00
16_A20_I1.6271.00
490_R662_I1.6181.00
23_A28_T1.6071.00
53_Q222_D1.6051.00
519_R549_C1.6041.00
168_G171_C1.5961.00
158_V161_E1.5961.00
639_D644_Y1.5841.00
10_Y13_Q1.5821.00
90_F224_A1.5811.00
308_V312_E1.5791.00
522_A576_A1.5721.00
412_F415_Y1.5661.00
529_C598_T1.5601.00
512_Q516_G1.5411.00
90_F218_I1.5321.00
60_V250_D1.5221.00
168_G172_E1.5200.99
534_P603_G1.5180.99
31_L471_L1.5090.99
543_H547_A1.4970.99
44_A457_M1.4960.99
110_R113_T1.4940.99
515_A546_L1.4930.99
456_L467_I1.4910.99
112_N115_E1.4910.99
8_S665_P1.4820.99
263_D649_P1.4820.99
311_Y315_L1.4800.99
517_A674_V1.4730.99
526_P574_D1.4690.99
591_F595_D1.4590.99
169_N173_R1.4560.99
515_A542_Y1.4500.99
262_E470_V1.4460.99
76_A225_V1.4450.99
620_Y624_F1.4370.99
565_L570_V1.4340.99
23_A453_A1.4310.99
19_A30_V1.4300.99
353_Q356_T1.4280.99
502_S505_R1.4260.99
170_V179_V1.4250.99
660_R663_R1.4140.99
262_E467_I1.4070.99
300_L311_Y1.4010.99
597_R668_F1.3990.99
311_Y314_A1.3970.99
63_T69_M1.3950.99
554_Y578_F1.3900.99
604_V650_T1.3870.99
552_T574_D1.3790.99
98_H209_C1.3780.99
353_Q357_G1.3770.99
651_V690_S1.3720.99
19_A22_D1.3690.99
416_P420_V1.3680.99
24_L455_V1.3680.99
303_F318_G1.3590.99
685_G689_Y1.3520.99
275_E431_G1.3510.99
161_E172_E1.3480.99
15_A18_D1.3260.99
339_A346_D1.3250.99
531_F576_A1.3220.99
333_W337_P1.3210.99
89_V225_V1.3200.99
565_L568_A1.3190.99
533_F539_A1.3180.99
259_H458_S1.3160.99
22_D477_V1.3140.99
659_G663_R1.3100.98
299_V302_A1.3090.98
516_G549_C1.3060.98
351_F357_G1.3050.98
498_E517_A1.3050.98
397_A401_F1.2970.98
35_A481_F1.2940.98
396_L400_E1.2930.98
384_N395_V1.2900.98
19_A477_V1.2890.98
340_N345_D1.2870.98
621_A645_A1.2860.98
65_V68_Q1.2860.98
525_T598_T1.2840.98
536_Y539_A1.2830.98
606_Y683_R1.2790.98
63_T67_Q1.2730.98
29_N453_A1.2680.98
37_G40_K1.2670.98
32_F481_F1.2660.98
98_H203_A1.2640.98
542_Y578_F1.2630.98
531_F578_F1.2610.98
384_N387_A1.2600.98
564_D567_E1.2600.98
20_I47_P1.2570.98
555_L572_D1.2570.98
606_Y647_E1.2510.98
340_N346_D1.2500.98
315_L319_G1.2480.98
31_L461_L1.2450.98
671_R694_T1.2370.98
313_D316_R1.2360.98
514_V518_L1.2350.98
468_G476_P1.2340.98
272_T434_E1.2290.98
464_F478_E1.2280.98
618_D622_Q1.2220.98
190_Y193_V1.2130.97
354_S357_G1.2100.97
656_Q659_G1.2090.97
412_F416_P1.2070.97
491_R694_T1.2050.97
641_G644_Y1.2030.97
643_R682_S1.2020.97
493_F673_L1.2020.97
86_R217_G1.2010.97
109_L113_T1.2000.97
106_C109_L1.1900.97
314_A318_G1.1890.97
394_H401_F1.1850.97
68_Q71_Q1.1840.97
166_Q171_C1.1750.97
161_E168_G1.1730.97
339_A342_D1.1680.97
332_N335_D1.1630.97
216_D219_E1.1610.97
399_A403_E1.1610.97
312_E315_L1.1590.97
161_E167_D1.1550.97
528_N573_G1.1530.97
541_R545_L1.1490.97
121_R124_R1.1400.96
49_L85_I1.1360.96
462_R480_A1.1290.96
97_C102_D1.1280.96
392_E396_L1.1270.96
556_D559_G1.1250.96
249_E450_A1.1250.96
330_E334_V1.1250.96
100_D204_E1.1190.96
344_R348_T1.1190.96
663_R667_D1.1080.96
173_R177_N1.1070.96
362_E365_T1.1020.96
564_D568_A1.1010.96
10_Y34_G1.1010.96
232_L261_I1.1000.96
520_D523_A1.0930.95
266_R436_Y1.0920.95
563_D567_E1.0900.95
540_K544_D1.0860.95
187_Q190_Y1.0840.95
391_R394_H1.0830.95
35_A484_Q1.0820.95
622_Q640_A1.0800.95
199_I204_E1.0790.95
336_V339_A1.0790.95
118_D121_R1.0770.95
162_L165_L1.0760.95
444_T448_F1.0730.95
600_A674_V1.0700.95
23_A27_G1.0670.95
504_N507_D1.0650.95
114_H119_A1.0640.95
351_F356_T1.0610.95
41_T587_E1.0580.94
253_V454_S1.0570.94
99_I210_G1.0550.94
17_M20_I1.0490.94
203_A209_C1.0450.94
272_T432_R1.0420.94
72_F87_A1.0420.94
556_D578_F1.0410.94
88_V214_L1.0380.94
168_G177_N1.0370.94
64_N260_N1.0370.94
88_V224_A1.0370.94
68_Q93_K1.0340.94
42_L603_G1.0330.94
451_V454_S1.0330.94
445_T449_D1.0310.94
169_N172_E1.0250.93
352_L355_Y1.0240.93
113_T116_L1.0180.93
412_F417_T1.0120.93
658_M694_T1.0110.93
614_E646_V1.0090.93
168_G173_R1.0070.93
188_W198_D1.0060.93
378_Y382_Y1.0050.93
542_Y545_L1.0040.93
565_L577_L1.0020.93
17_M21_R1.0020.93
266_R617_Q1.0000.93
35_A483_L0.9990.93
336_V340_N0.9970.92
121_R125_Q0.9970.92
63_T227_N0.9940.92
226_C231_L0.9850.92
170_V177_N0.9820.92
384_N390_R0.9790.92
601_V654_T0.9760.92
514_V674_V0.9740.92
601_V658_M0.9710.91
264_A267_D0.9710.91
510_T514_V0.9690.91
49_L223_L0.9670.91
396_L401_F0.9620.91
176_Q179_V0.9610.91
170_V176_Q0.9610.91
65_V93_K0.9540.91
334_V337_P0.9510.91
395_V399_A0.9510.91
108_V112_N0.9500.91
105_E109_L0.9480.90
35_A487_E0.9470.90
193_V199_I0.9440.90
234_P248_P0.9420.90
341_D344_R0.9410.90
411_E415_Y0.9410.90
165_L168_G0.9400.90
395_V402_V0.9390.90
303_F310_T0.9370.90
414_Q421_R0.9310.90
105_E108_V0.9300.90
656_Q660_R0.9280.90
458_S472_G0.9280.90
332_N339_A0.9260.89
345_D348_T0.9250.89
172_E177_N0.9240.89
34_G227_N0.9210.89
379_E383_R0.9200.89
81_A84_P0.9200.89
63_T68_Q0.9190.89
254_V465_D0.9170.89
333_W336_V0.9160.89
64_N67_Q0.9140.89
330_E333_W0.9130.89
390_R402_V0.9120.89
487_E662_I0.9120.89
486_P490_R0.9110.89
304_R310_T0.9100.89
57_K251_V0.9100.89
332_N336_V0.9090.89
538_E602_V0.9050.88
400_E403_E0.9050.88
396_L402_V0.9030.88
402_V408_R0.9030.88
530_L599_V0.9030.88
232_L265_A0.9010.88
114_H117_V0.9000.88
378_Y381_A0.8960.88
681_A684_T0.8950.88
590_S669_G0.8950.88
573_G594_D0.8940.88
505_R509_A0.8890.87
331_S334_V0.8870.87
384_N402_V0.8820.87
93_K211_Y0.8820.87
481_F592_D0.8810.87
330_E338_V0.8800.87
350_A354_S0.8780.87
504_N676_R0.8760.87
193_V197_E0.8750.87
656_Q663_R0.8720.86
93_K234_P0.8720.86
26_G477_V0.8710.86
301_G305_D0.8710.86
337_P341_D0.8710.86
66_H71_Q0.8700.86
342_D345_D0.8650.86
528_N591_F0.8650.86
109_L117_V0.8630.86
464_F472_G0.8630.86
229_H268_H0.8620.86
248_P464_F0.8600.86
308_V318_G0.8590.86
165_L172_E0.8580.86
191_D198_D0.8560.85
44_A228_Y0.8520.85
11_D14_R0.8490.85
528_N598_T0.8490.85
113_T117_V0.8480.85
492_T670_V0.8480.85
660_R669_G0.8470.85
663_R669_G0.8450.85
402_V405_Y0.8450.85
377_E380_D0.8440.85
165_L169_N0.8440.85
336_V341_D0.8440.85
552_T576_A0.8440.85
257_E660_R0.8430.84
50_S528_N0.8410.84
332_N338_V0.8360.84
545_L549_C0.8360.84
374_L409_G0.8340.84
498_E513_A0.8340.84
614_E645_A0.8330.84
523_A551_A0.8310.84
388_T391_R0.8310.84
614_E618_D0.8300.84
36_C65_V0.8230.83
91_K98_H0.8210.83
511_Q514_V0.8210.83
31_L464_F0.8200.83
350_A353_Q0.8160.83
538_E542_Y0.8160.83
458_S590_S0.8160.83
38_T464_F0.8150.82
337_P344_R0.8140.82
42_L479_L0.8140.82
399_A402_V0.8140.82
297_E301_G0.8110.82
17_M42_L0.8090.82
257_E659_G0.8070.82
346_D349_L0.8070.82
650_T669_G0.8060.82
252_V453_A0.8030.82
158_V165_L0.8020.81
386_D390_R0.8000.81
657_A669_G0.7990.81
652_R662_I0.7980.81
86_R222_D0.7970.81
566_R595_D0.7960.81
71_Q77_R0.7960.81
485_F490_R0.7940.81
537_A541_R0.7920.81
120_T124_R0.7920.81
447_L451_V0.7900.80
530_L575_G0.7900.80
51_H252_V0.7890.80
339_A345_D0.7880.80
231_L253_V0.7880.80
393_C396_L0.7870.80
344_R347_L0.7870.80
570_V594_D0.7860.80
166_Q172_E0.7850.80
544_D548_D0.7850.80
31_L649_P0.7850.80
98_H198_D0.7840.80
648_I686_M0.7840.80
21_R25_D0.7830.80
303_F311_Y0.7830.80
97_C223_L0.7810.80
210_G586_A0.7800.80
530_L591_F0.7800.80
415_Y420_V0.7790.80
174_Y177_N0.7770.79
568_A571_A0.7770.79
73_V285_L0.7760.79
339_A344_R0.7760.79
311_Y317_P0.7750.79
553_R575_G0.7750.79
38_T690_S0.7750.79
569_F595_D0.7740.79
673_L691_V0.7740.79
394_H397_A0.7740.79
297_E300_L0.7740.79
376_G571_A0.7720.79
69_M268_H0.7720.79
395_V398_A0.7700.79
87_A223_L0.7700.79
20_I32_F0.7680.79
302_A305_D0.7670.78
349_L352_L0.7660.78
77_R198_D0.7650.78
555_L568_A0.7650.78
336_V342_D0.7640.78
550_D553_R0.7620.78
59_V71_Q0.7600.78
65_V578_F0.7560.77
366_D369_G0.7540.77
512_Q541_R0.7540.77
561_A564_D0.7530.77
97_C273_L0.7520.77
10_Y16_A0.7520.77
106_C110_R0.7510.77
228_Y532_F0.7510.77
113_T120_T0.7500.77
75_E437_T0.7490.77
521_A600_A0.7480.77
676_R680_A0.7480.77
188_W193_V0.7460.77
264_A536_Y0.7450.76
530_L657_A0.7450.76
171_C174_Y0.7450.76
20_I23_A0.7430.76
588_G659_G0.7430.76
99_I208_F0.7420.76
311_Y318_G0.7420.76
110_R114_H0.7400.76
117_V120_T0.7400.76
393_C400_E0.7400.76
460_T588_G0.7390.76
541_R544_D0.7390.76
187_Q191_D0.7380.76
171_C177_N0.7370.76
621_A644_Y0.7360.76
92_G485_F0.7360.76
97_C278_L0.7360.76
170_V674_V0.7350.75
119_A122_D0.7340.75
91_K661_V0.7330.75
589_V614_E0.7320.75
262_E265_A0.7310.75
36_C227_N0.7310.75
102_D162_L0.7300.75
553_R573_G0.7280.75
351_F355_Y0.7280.75
64_N687_Q0.7270.75
61_I228_Y0.7220.74
367_A370_L0.7200.74
372_E376_G0.7190.74
41_T284_E0.7190.74
621_A624_F0.7180.74
687_Q690_S0.7180.74
465_D469_D0.7170.74
508_R512_Q0.7130.73
393_C398_A0.7120.73
86_R221_V0.7100.73
286_Q308_V0.7100.73
464_F467_I0.7100.73
488_D693_P0.7070.73
590_S650_T0.7070.73
308_V314_A0.7060.72
64_N68_Q0.7060.72
99_I102_D0.7040.72
367_A373_Y0.7040.72
515_A519_R0.7030.72
369_G372_E0.7020.72
441_R456_L0.7020.72
338_V345_D0.7010.72
458_S669_G0.7010.72
398_A402_V0.6980.72
392_E395_V0.6970.72
122_D455_V0.6970.72
409_G412_F0.6970.72
115_E119_A0.6960.71
660_R667_D0.6950.71
65_V605_P0.6930.71
385_G404_A0.6930.71
300_L314_A0.6930.71
66_H95_S0.6930.71
255_F456_L0.6930.71
46_A51_H0.6920.71
643_R647_E0.6900.71
341_D345_D0.6900.71
212_E528_N0.6900.71
75_E78_E0.6890.71
506_E541_R0.6880.71
317_P320_D0.6870.70
6_K488_D0.6870.70
460_T663_R0.6870.70
306_A311_Y0.6860.70
580_S586_A0.6850.70
527_G591_F0.6850.70
211_Y232_L0.6840.70
507_D512_Q0.6830.70
85_I222_D0.6830.70
376_G379_E0.6820.70
47_P50_S0.6810.70
525_T597_R0.6790.70
410_G415_Y0.6780.69
621_A625_A0.6780.69
491_R658_M0.6780.69
554_Y560_V0.6780.69
625_A642_W0.6770.69
248_P593_G0.6760.69
342_D346_D0.6760.69
116_L355_Y0.6750.69
527_G569_F0.6750.69
378_Y384_N0.6740.69
497_T699_E0.6730.69
21_R54_A0.6710.69
257_E656_Q0.6710.69
354_S358_P0.6700.69
651_V654_T0.6700.69
642_W684_T0.6700.69
527_G574_D0.6680.68
23_A455_V0.6680.68
171_C176_Q0.6670.68
577_L585_L0.6670.68
311_Y316_R0.6670.68
603_G678_Y0.6670.68
191_D194_R0.6660.68
509_A554_Y0.6660.68
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85_I223_L0.6640.68
528_N668_F0.6630.68
49_L76_A0.6630.68
333_W342_D0.6630.68
553_R568_A0.6620.68
257_E588_G0.6610.67
521_A674_V0.6610.67
239_Q245_G0.6600.67
380_D384_N0.6600.67
365_T372_E0.6580.67
13_Q39_G0.6580.67
159_E163_A0.6580.67
170_V175_R0.6570.67
586_A655_R0.6560.67
257_E663_R0.6550.67
516_G520_D0.6540.67
346_D350_A0.6540.67
213_L217_G0.6530.67
108_V111_D0.6520.66
316_R696_P0.6520.66
378_Y389_T0.6520.66
466_V470_V0.6510.66
69_M73_V0.6500.66
389_T392_E0.6490.66
265_A437_T0.6490.66
20_I457_M0.6480.66
116_L119_A0.6470.66
50_S230_H0.6470.66
373_Y377_E0.6460.66
230_H234_P0.6460.66
511_Q545_L0.6450.66
98_H210_G0.6450.66
328_A334_V0.6450.66
9_P14_R0.6440.65
35_A44_A0.6440.65
232_L435_R0.6430.65
375_D378_Y0.6420.65
460_T659_G0.6420.65
231_L539_A0.6420.65
467_I470_V0.6410.65
34_G44_A0.6410.65
118_D122_D0.6410.65
318_G321_G0.6410.65
30_V477_V0.6400.65
306_A363_D0.6400.65
526_P668_F0.6400.65
596_A661_V0.6400.65
588_G660_R0.6390.65
200_Y599_V0.6390.65
305_D309_E0.6390.65
21_R50_S0.6390.65
42_L456_L0.6370.65
117_V121_R0.6370.65
311_Y319_G0.6370.65
624_F639_D0.6370.65
194_R671_R0.6370.65
659_G669_G0.6360.65
393_C401_F0.6360.65
13_Q40_K0.6350.64
59_V223_L0.6340.64
69_M538_E0.6340.64
300_L307_L0.6330.64
417_T420_V0.6330.64
90_F230_H0.6320.64
411_E414_Q0.6310.64
44_A61_I0.6290.64
330_E335_D0.6290.64
66_H69_M0.6290.64
368_L512_Q0.6280.64
413_G417_T0.6280.64
229_H436_Y0.6270.63
43_A625_A0.6270.63
495_V679_T0.6270.63
397_A409_G0.6260.63
440_P463_P0.6260.63
201_G276_Q0.6250.63
74_R88_V0.6240.63
379_E382_Y0.6240.63
18_D22_D0.6240.63
519_R546_L0.6240.63
334_V341_D0.6220.63
588_G663_R0.6220.63
310_T313_D0.6210.63
227_N593_G0.6210.63
463_P574_D0.6210.63
557_E603_G0.6210.63
308_V311_Y0.6200.63
302_A311_Y0.6200.63
17_M597_R0.6190.62
602_V674_V0.6190.62
76_A478_E0.6190.62
534_P586_A0.6180.62
45_L657_A0.6170.62
470_V617_Q0.6150.62
114_H223_L0.6150.62
116_L397_A0.6150.62
306_A315_L0.6150.62
91_K227_N0.6140.62
331_S339_A0.6130.62
360_I364_V0.6120.62
384_N389_T0.6110.61
381_A384_N0.6110.61
338_V344_R0.6110.61
288_T295_A0.6110.61
336_V345_D0.6100.61
331_S343_R0.6100.61
439_I610_D0.6090.61
187_Q193_V0.6090.61
392_E403_E0.6090.61
106_C111_D0.6080.61
370_L374_L0.6070.61
383_R387_A0.6070.61
61_I72_F0.6060.61
95_S274_T0.6050.61
160_S165_L0.6050.61
511_Q515_A0.6050.61
365_T368_L0.6040.61
525_T670_V0.6040.61
530_L592_D0.6040.61
377_E381_A0.6030.60
116_L301_G0.6030.60
331_S336_V0.6030.60
683_R692_N0.6020.60
405_Y409_G0.6020.60
117_V123_K0.6010.60
228_Y234_P0.6010.60
114_H118_D0.6010.60
13_Q37_G0.5990.60
393_C397_A0.5990.60
97_C165_L0.5990.60
369_G373_Y0.5980.60
194_R197_E0.5970.60
328_A336_V0.5970.60
510_T645_A0.5970.60
616_V619_A0.5970.60
343_R619_A0.5970.60
394_H402_V0.5960.60
16_A43_A0.5960.60
343_R347_L0.5950.59
211_Y215_K0.5930.59
115_E118_D0.5920.59
360_I370_L0.5900.59
236_I269_A0.5900.59
170_V647_E0.5880.59
306_A317_P0.5880.59
303_F306_A0.5870.58
341_D347_L0.5870.58
42_L46_A0.5860.58
110_R116_L0.5860.58
166_Q169_N0.5860.58
518_L522_A0.5860.58
304_R314_A0.5860.58
101_V416_P0.5850.58
588_G656_Q0.5850.58
408_R411_E0.5840.58
316_R319_G0.5830.58
290_D535_S0.5830.58
684_T692_N0.5830.58
168_G174_Y0.5820.58
300_L317_P0.5820.58
652_R655_R0.5810.58
381_A390_R0.5810.58
659_G667_D0.5810.58
332_N344_R0.5800.57
277_T280_S0.5800.57
75_E200_Y0.5800.57
511_Q542_Y0.5800.57
522_A525_T0.5790.57
262_E579_T0.5790.57
43_A52_A0.5780.57
46_A79_I0.5780.57
274_T277_T0.5780.57
334_V340_N0.5770.57
48_A616_V0.5770.57
193_V196_P0.5770.57
91_K169_N0.5760.57
40_K588_G0.5750.57
257_E460_T0.5750.57
64_N264_A0.5740.57
64_N93_K0.5740.57
227_N485_F0.5730.57
122_D125_Q0.5720.56
36_C438_C0.5720.56
29_N32_F0.5710.56
393_C402_V0.5700.56
460_T660_R0.5690.56
234_P268_H0.5690.56
118_D403_E0.5680.56
299_V313_D0.5670.56
109_L112_N0.5670.56
360_I369_G0.5670.56
190_Y515_A0.5660.56
187_Q198_D0.5660.56
494_A672_M0.5660.56
304_R307_L0.5650.56
528_N574_D0.5640.55
15_A479_L0.5640.55
527_G597_R0.5640.55
511_Q541_R0.5630.55
369_G375_D0.5630.55
20_I252_V0.5630.55
192_D198_D0.5620.55
560_V577_L0.5610.55
598_T670_V0.5600.55
43_A47_P0.5600.55
265_A585_L0.5600.55
113_T119_A0.5580.55
38_T211_Y0.5580.55
651_V655_R0.5580.55
70_R612_R0.5580.55
48_A600_A0.5570.54
407_E410_G0.5570.54
296_A300_L0.5570.54
193_V673_L0.5570.54
17_M47_P0.5560.54
230_H233_D0.5560.54
350_A358_P0.5560.54
522_A552_T0.5560.54
91_K95_S0.5560.54
292_R295_A0.5550.54
482_G693_P0.5540.54
34_G38_T0.5530.54
436_Y613_T0.5530.54
591_F597_R0.5530.54
93_K232_L0.5520.54
485_F593_G0.5520.54
309_E410_G0.5520.54
524_Y668_F0.5510.54
655_R687_Q0.5510.54
160_S166_Q0.5510.54
589_V662_I0.5500.54
45_L79_I0.5500.54
161_E164_A0.5490.53
300_L315_L0.5480.53
579_T694_T0.5470.53
654_T691_V0.5470.53
441_R599_V0.5460.53
295_A387_A0.5450.53
161_E169_N0.5450.53
548_D551_A0.5450.53
57_K673_L0.5440.53
310_T319_G0.5440.53
91_K96_M0.5430.53
329_V333_W0.5430.53
404_A410_G0.5430.53
313_D317_P0.5430.53
441_R472_G0.5420.52
10_Y44_A0.5420.52
49_L280_S0.5420.52
543_H559_G0.5420.52
115_E120_T0.5410.52
651_V686_M0.5410.52
302_A306_A0.5400.52
80_H85_I0.5400.52
383_R389_T0.5400.52
6_K13_Q0.5400.52
36_C39_G0.5390.52
498_E673_L0.5390.52
109_L114_H0.5390.52
536_Y596_A0.5390.52
33_E480_A0.5380.52
514_V602_V0.5380.52
188_W194_R0.5380.52
33_E655_R0.5380.52
256_D656_Q0.5380.52
10_Y532_F0.5370.52
44_A225_V0.5370.52
236_I239_Q0.5370.52
543_H578_F0.5350.52
229_H264_A0.5350.52
206_A212_E0.5330.51
24_L453_A0.5320.51
116_L123_K0.5320.51
466_V648_I0.5310.51
532_F661_V0.5300.51
61_I442_E0.5300.51
105_E112_N0.5300.51
41_T71_Q0.5290.51
108_V118_D0.5280.51
593_G664_S0.5270.51
365_T409_G0.5270.51
650_T683_R0.5270.51
477_V518_L0.5270.51
273_L350_A0.5270.51
90_F653_K0.5270.51
552_T597_R0.5260.50
299_V304_R0.5260.50
481_F651_V0.5260.50
537_A540_K0.5250.50
414_Q420_V0.5250.50
96_M532_F0.5250.50
352_L357_G0.5240.50
309_E312_E0.5240.50
18_D24_L0.5230.50
277_T397_A0.5220.50
528_N596_A0.5220.50
278_L285_L0.5220.50
65_V75_E0.5220.50
286_Q445_T0.5220.50
387_A398_A0.5220.50
349_L354_S0.5210.50
303_F316_R0.5210.50
161_E171_C0.5200.50
63_T66_H0.5190.49
36_C40_K0.5180.49
10_Y661_V0.5180.49
79_I93_K0.5180.49
642_W683_R0.5180.49
92_G230_H0.5180.49
306_A319_G0.5170.49
59_V68_Q0.5170.49
480_A655_R0.5160.49
98_H532_F0.5160.49
170_V360_I0.5160.49
394_H400_E0.5150.49
307_L321_G0.5140.49
198_D209_C0.5140.49
377_E384_N0.5140.49
591_F664_S0.5140.49
32_F457_M0.5130.49
92_G227_N0.5120.49
339_A601_V0.5120.49
202_Y578_F0.5120.49
266_R270_A0.5110.48
205_E208_F0.5100.48
17_M32_F0.5100.48
48_A352_L0.5100.48
378_Y395_V0.5090.48
37_G41_T0.5080.48
110_R117_V0.5080.48
267_D319_G0.5080.48
265_A648_I0.5080.48
66_H596_A0.5080.48
44_A459_A0.5060.48
296_A299_V0.5060.48
482_G590_S0.5060.48
278_L311_Y0.5060.48
383_R402_V0.5050.48
437_T458_S0.5050.48
228_Y487_E0.5050.48
10_Y596_A0.5040.47
658_M691_V0.5040.47
508_R516_G0.5040.47
554_Y567_E0.5020.47
109_L116_L0.5010.47
74_R96_M0.5000.47
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4a15A 1 0.8005 100 0.364 Contact Map
3crvA 1 0.7391 100 0.417 Contact Map
2vl7A 1 0.623 100 0.457 Contact Map
1gkuB 1 0.5574 100 0.789 Contact Map
3fhoA 2 0.4098 100 0.812 Contact Map
4ys0A 1 0.7582 100 0.814 Contact Map
4dduA 1 0.5683 100 0.816 Contact Map
4w7sA 2 0.5164 100 0.83 Contact Map
3oiyA 1 0.5232 100 0.83 Contact Map
2ykgA 1 0.6585 100 0.834 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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