DPS - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

DPS - DNA protection during starvation protein

UniProt:	Q9HMP7	Sequences: MSTQKNARATAGEVEGSDALRMDADRAEQCVDALNADLANVYVLYHQLKKHHWNVEGAEFRDLHLFLGEAAETAEEVADELAERVQALGGVPHASPETLQAEASVDVEDEDVYDIRTSLANDMAIYGDIIEATREHTELAENLGDHATAHMLREGLIELEDDAHHIEHYLEDDTLVTQGALE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	182 (151)
Sequences:	2922 (1688)
Seq/√Len:	137.4

ECOLI - DPS
BACSU - MRGA G20U
HALSA - DPS

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
114_D	117_T	3.419	1.00
31_V	90_G	2.972	1.00
150_H	154_E	2.820	1.00
141_E	149_A	2.637	1.00
51_H	121_N	2.582	1.00
47_Q	125_I	2.566	1.00
61_R	65_L	2.416	1.00
97_E	101_A	2.389	1.00
40_N	104_S	2.355	1.00
48_L	74_A	2.285	1.00
150_H	153_R	2.272	1.00
137_T	153_R	2.043	1.00
93_H	102_E	2.038	1.00
140_A	149_A	1.918	1.00
68_G	72_E	1.849	1.00
149_A	153_R	1.799	1.00
42_Y	99_L	1.785	1.00
147_A	156_L	1.777	1.00
63_L	67_L	1.708	1.00
73_T	162_D	1.673	1.00
51_H	118_S	1.658	1.00
46_H	96_P	1.653	1.00
35_N	93_H	1.631	1.00
84_R	145_D	1.613	1.00
141_E	146_H	1.608	1.00
138_E	142_N	1.570	1.00
138_E	144_G	1.552	1.00
123_M	163_A	1.549	1.00
127_G	167_E	1.537	1.00
33_A	136_H	1.536	1.00
127_G	131_E	1.524	1.00
146_H	149_A	1.513	1.00
66_F	69_E	1.508	1.00
41_V	81_L	1.461	1.00
23_D	26_R	1.458	1.00
120_A	124_A	1.456	1.00
130_I	163_A	1.455	1.00
66_F	70_A	1.427	1.00
73_T	158_E	1.419	1.00
134_R	160_E	1.414	1.00
43_V	100_Q	1.370	1.00
68_G	71_A	1.368	1.00
29_Q	32_D	1.350	1.00
73_T	77_V	1.347	1.00
84_R	148_T	1.342	1.00
130_I	160_E	1.331	1.00
70_A	126_Y	1.314	1.00
50_K	94_A	1.313	1.00
40_N	132_A	1.310	1.00
77_V	155_G	1.286	1.00
163_A	167_E	1.285	1.00
80_E	151_M	1.268	1.00
51_H	108_E	1.235	1.00
41_V	74_A	1.215	1.00
48_L	70_A	1.213	1.00
116_R	120_A	1.199	1.00
136_H	152_L	1.191	1.00
145_D	148_T	1.186	1.00
137_T	149_A	1.186	1.00
130_I	156_L	1.184	1.00
131_E	135_E	1.178	0.99
39_A	102_E	1.172	0.99
43_V	103_A	1.158	0.99
28_E	32_D	1.156	0.99
77_V	158_E	1.147	0.99
117_T	120_A	1.146	0.99
30_C	143_L	1.134	0.99
127_G	163_A	1.125	0.99
119_L	166_I	1.082	0.99
61_R	69_E	1.079	0.99
45_Y	75_E	1.049	0.99
126_Y	162_D	1.043	0.99
33_A	139_L	1.040	0.99
158_E	161_D	1.039	0.99
84_R	160_E	1.038	0.99
134_R	156_L	1.035	0.99
37_D	136_H	1.033	0.99
61_R	66_F	1.019	0.99
42_Y	78_A	1.015	0.98
49_K	78_A	1.014	0.98
108_E	118_S	1.010	0.98
67_L	118_S	1.008	0.98
123_M	167_E	1.005	0.98
147_A	157_I	1.002	0.98
36_A	132_A	0.999	0.98
35_N	85_V	0.970	0.98
38_L	81_L	0.969	0.98
89_G	167_E	0.967	0.98
43_V	96_P	0.966	0.98
140_A	148_T	0.964	0.98
104_S	128_D	0.961	0.98
88_L	148_T	0.954	0.98
37_D	133_T	0.950	0.98
137_T	156_L	0.946	0.98
75_E	78_A	0.942	0.98
22_M	27_A	0.933	0.97
24_A	27_A	0.930	0.97
36_A	104_S	0.922	0.97
124_A	127_G	0.914	0.97
104_S	132_A	0.909	0.97
40_N	103_A	0.904	0.97
51_H	109_D	0.898	0.97
137_T	146_H	0.898	0.97
30_C	140_A	0.886	0.96
72_E	76_E	0.879	0.96
26_R	142_N	0.877	0.96
146_H	153_R	0.877	0.96
64_H	83_E	0.869	0.96
24_A	28_E	0.862	0.96
31_V	85_V	0.858	0.96
62_D	169_Y	0.850	0.95
98_T	110_E	0.850	0.95
22_M	134_R	0.835	0.95
98_T	101_A	0.831	0.95
126_Y	159_L	0.824	0.95
138_E	146_H	0.818	0.94
33_A	135_E	0.814	0.94
161_D	164_H	0.790	0.93
130_I	159_L	0.784	0.93
37_D	132_A	0.783	0.93
120_A	170_L	0.776	0.93
117_T	121_N	0.775	0.93
49_K	71_A	0.774	0.93
123_M	127_G	0.770	0.92
76_E	80_E	0.763	0.92
56_E	171_E	0.756	0.92
66_F	165_H	0.754	0.92
25_D	28_E	0.752	0.92
65_L	69_E	0.749	0.91
122_D	126_Y	0.747	0.91
46_H	94_A	0.745	0.91
22_M	26_R	0.745	0.91
98_T	102_E	0.732	0.90
67_L	119_L	0.729	0.90
61_R	169_Y	0.726	0.90
54_N	92_P	0.723	0.90
80_E	154_E	0.721	0.90
49_K	165_H	0.719	0.90
154_E	157_I	0.718	0.90
62_D	65_L	0.718	0.90
59_E	115_I	0.714	0.89
60_F	83_E	0.714	0.89
59_E	116_R	0.711	0.89
132_A	135_E	0.707	0.89
52_H	64_H	0.706	0.89
140_A	152_L	0.705	0.89
133_T	152_L	0.698	0.88
38_L	41_V	0.696	0.88
133_T	159_L	0.695	0.88
158_E	162_D	0.690	0.88
55_V	118_S	0.688	0.87
119_L	169_Y	0.682	0.87
45_Y	81_L	0.681	0.87
40_N	128_D	0.681	0.87
133_T	155_G	0.681	0.87
52_H	83_E	0.680	0.87
105_V	132_A	0.680	0.87
35_N	39_A	0.676	0.87
58_A	116_R	0.671	0.86
59_E	169_Y	0.671	0.86
29_Q	139_L	0.670	0.86
29_Q	142_N	0.655	0.85
49_K	68_G	0.650	0.84
41_V	77_V	0.648	0.84
54_N	94_A	0.648	0.84
93_H	98_T	0.646	0.84
33_A	140_A	0.646	0.84
106_D	124_A	0.642	0.84
87_A	161_D	0.638	0.83
56_E	168_H	0.638	0.83
38_L	78_A	0.630	0.83
46_H	99_L	0.630	0.83
33_A	36_A	0.627	0.82
96_P	100_Q	0.626	0.82
135_E	139_L	0.625	0.82
116_R	119_L	0.611	0.81
91_V	112_V	0.611	0.81
70_A	166_I	0.609	0.80
126_Y	166_I	0.609	0.80
123_M	170_L	0.607	0.80
44_L	48_L	0.607	0.80
68_G	75_E	0.606	0.80
85_V	90_G	0.604	0.80
130_I	134_R	0.604	0.80
30_C	139_L	0.604	0.80
147_A	160_E	0.603	0.80
32_D	36_A	0.595	0.79
135_E	138_E	0.592	0.78
108_E	111_D	0.589	0.78
97_E	108_E	0.588	0.78
52_H	60_F	0.586	0.78
60_F	64_H	0.577	0.77
45_Y	78_A	0.574	0.76
130_I	147_A	0.574	0.76
55_V	67_L	0.573	0.76
20_L	24_A	0.573	0.76
109_D	121_N	0.573	0.76
69_E	72_E	0.567	0.75
80_E	157_I	0.565	0.75
84_R	88_L	0.563	0.75
105_V	125_I	0.561	0.75
35_N	92_P	0.555	0.74
63_L	119_L	0.549	0.73
37_D	40_N	0.538	0.72
71_A	82_A	0.537	0.71
145_D	160_E	0.537	0.71
47_Q	109_D	0.535	0.71
165_H	168_H	0.533	0.71
70_A	74_A	0.531	0.71
138_E	141_E	0.531	0.71
37_D	152_L	0.529	0.70
47_Q	105_V	0.528	0.70
156_L	160_E	0.526	0.70
56_E	86_Q	0.525	0.70
137_T	140_A	0.520	0.69
60_F	165_H	0.519	0.69
150_H	157_I	0.517	0.69
36_A	102_E	0.517	0.69
95_S	98_T	0.513	0.68
71_A	165_H	0.510	0.68
33_A	132_A	0.510	0.68
26_R	30_C	0.507	0.67
70_A	122_D	0.507	0.67
63_L	118_S	0.505	0.67
153_R	156_L	0.505	0.67
139_L	142_N	0.500	0.66

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1zs3A	6	0.9286	100	0.319	Contact Map
1zujA	6	0.9121	100	0.323	Contact Map
3ak8A	6	0.8516	100	0.324	Contact Map
1tjoA	6	0.9835	100	0.335	Contact Map
2c2uA	6	0.956	100	0.348	Contact Map
4cybA	6	0.9396	100	0.35	Contact Map
2c2jA	6	0.8681	100	0.353	Contact Map
2wluA	6	0.9066	100	0.381	Contact Map
4a25A	8	0.9286	100	0.384	Contact Map
2vxxA	6	0.9505	100	0.385	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.007 seconds.