SRP54 - HALSA - GREMLIN Contacts

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SRP54 - Signal recognition particle 54 kDa protein

UniProt:	Q9HMN5	Sequences: MVLDDLGSSLRGTLDTLRGKSRISEEDVDKVVKEIQRSLLQADVDVDLVMDLSESITERSLEEEPPGGTSARDHVLRIVYEELVGLVGDSTPIPLEEQTIMLAGLQGSGKTTTAAKMAWWFSKKGLRPAIVQTDTFRPGAYEQAAEMADRAEVDFYGEPDSDDPVQIARDGLAATADADVHIVDTAGRHALEDDLIAEIEEIEGVVEPDRSLLVLDAAIGQGAKQQARQFDASIGIDGVAITKLDGTAKGGGSLTAVNETDSTIAFLGSGETVQDIERFEPDSFISRLLGMGDLKQLTERVERAMEETQDDDEDWDPEDLMKGEFTLHDMRKQMQAMDNMGPLDQVMDMIPGMGGGLMDELPDDAMDVTQERMRGFEVIMDSMTEAEMADPRSVGASQIRRIARGSGQPEDRVRELLDQHKMMAQTMQQFQGMGDGDMQRMMSKMQQQGGGGGGGFGGMF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	460 (431)
Sequences:	2868 (1322)
Seq/√Len:	63.7

ECOLI - SRP54
BACSU - SRP54
HALSA - SRP54
SULSO - SRP54

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
148_A	155_F	5.151	1.00
102_L	114_A	4.268	1.00
200_E	233_S	3.968	1.00
309_Q	332_K	3.853	1.00
228_R	232_A	3.781	1.00
328_H	389_A	3.748	1.00
142_E	145_A	3.690	1.00
335_Q	377_E	3.536	1.00
190_A	222_G	3.337	1.00
29_D	57_T	3.286	1.00
197_A	201_E	3.037	1.00
158_E	170_D	3.026	1.00
231_D	262_S	2.991	1.00
115_A	273_V	2.962	1.00
338_D	377_E	2.902	1.00
400_R	404_R	2.897	1.00
270_G	275_D	2.794	1.00
114_A	182_I	2.791	1.00
331_R	381_D	2.714	1.00
394_V	417_L	2.581	1.00
409_P	412_R	2.581	1.00
115_A	147_M	2.578	1.00
51_D	258_N	2.544	1.00
69_T	298_T	2.517	1.00
156_Y	170_D	2.509	1.00
183_V	206_V	2.489	1.00
166_Q	170_D	2.479	1.00
154_D	178_A	2.464	1.00
168_A	206_V	2.422	1.00
114_A	130_I	2.388	1.00
52_L	56_I	2.385	1.00
131_V	171_G	2.384	1.00
82_E	85_G	2.314	1.00
330_M	420_H	2.312	1.00
403_A	413_V	2.230	1.00
386_A	393_S	2.209	1.00
145_A	149_D	2.206	1.00
163_D	201_E	2.206	1.00
123_K	303_R	2.182	1.00
163_D	166_Q	2.161	1.00
130_I	148_A	2.157	1.00
317_P	321_M	2.101	1.00
295_K	298_T	2.100	1.00
121_F	180_V	2.098	1.00
165_V	205_V	2.089	1.00
327_L	417_L	2.089	1.00
435_D	438_M	2.081	1.00
133_T	168_A	2.060	1.00
379_I	413_V	2.051	1.00
122_S	152_E	2.022	1.00
85_G	89_D	1.989	1.00
122_S	153_V	1.977	1.00
350_I	353_M	1.973	1.00
307_E	314_D	1.952	1.00
126_L	180_V	1.937	1.00
77_R	81_E	1.924	1.00
212_L	240_A	1.907	1.00
309_Q	315_W	1.899	1.00
210_R	265_A	1.882	1.00
67_G	308_T	1.878	1.00
59_R	81_E	1.877	1.00
59_R	82_E	1.874	1.00
314_D	317_P	1.832	1.00
377_E	381_D	1.826	1.00
130_I	182_I	1.826	1.00
118_A	153_V	1.813	1.00
20_K	27_D	1.813	1.00
127_R	178_A	1.803	1.00
394_V	402_I	1.783	1.00
244_L	267_L	1.781	1.00
375_G	412_R	1.771	1.00
135_T	167_I	1.730	0.99
54_E	58_E	1.727	0.99
51_D	55_S	1.723	0.99
236_I	262_S	1.713	0.99
211_S	234_I	1.701	0.99
91_T	278_R	1.695	0.99
165_V	201_E	1.695	0.99
55_S	85_G	1.684	0.99
145_A	157_G	1.632	0.99
212_L	238_G	1.621	0.99
136_F	167_I	1.620	0.99
80_Y	84_V	1.619	0.99
203_E	235_G	1.618	0.99
197_A	200_E	1.615	0.99
244_L	284_F	1.615	0.99
202_I	206_V	1.600	0.99
386_A	390_D	1.595	0.99
371_E	374_R	1.587	0.99
172_L	181_H	1.582	0.99
131_V	181_H	1.580	0.99
375_G	408_Q	1.579	0.99
328_H	385_E	1.571	0.99
99_T	183_V	1.567	0.99
128_P	178_A	1.552	0.99
59_R	85_G	1.548	0.99
420_H	424_A	1.514	0.99
117_M	240_A	1.514	0.99
326_T	389_A	1.512	0.99
147_M	151_A	1.510	0.99
80_Y	286_S	1.498	0.98
94_P	98_Q	1.495	0.98
399_I	417_L	1.491	0.98
314_D	318_E	1.489	0.98
151_A	273_V	1.476	0.98
203_E	211_S	1.459	0.98
241_I	253_S	1.459	0.98
283_S	299_E	1.457	0.98
437_D	440_R	1.455	0.98
17_L	31_V	1.446	0.98
32_V	57_T	1.445	0.98
408_Q	412_R	1.444	0.98
119_W	274_Q	1.439	0.98
54_E	57_T	1.433	0.98
128_P	154_D	1.432	0.98
300_R	349_M	1.428	0.98
120_W	266_F	1.422	0.98
147_M	273_V	1.420	0.98
149_D	152_E	1.409	0.98
113_T	268_G	1.408	0.98
28_V	61_L	1.391	0.97
135_T	164_P	1.389	0.97
306_E	309_Q	1.375	0.97
436_G	440_R	1.368	0.97
215_L	256_A	1.367	0.97
98_Q	209_D	1.360	0.97
99_T	172_L	1.352	0.97
433_M	438_M	1.344	0.97
343_L	347_M	1.342	0.97
129_A	178_A	1.337	0.97
131_V	168_A	1.327	0.97
229_Q	233_S	1.323	0.97
100_I	182_I	1.322	0.97
120_W	124_K	1.310	0.96
345_Q	348_D	1.292	0.96
55_S	82_E	1.292	0.96
379_I	416_L	1.292	0.96
51_D	54_E	1.285	0.96
200_E	204_G	1.281	0.96
222_G	225_Q	1.279	0.96
130_I	155_F	1.277	0.96
269_S	276_I	1.273	0.96
308_T	315_W	1.270	0.96
335_Q	381_D	1.268	0.96
190_A	229_Q	1.265	0.96
165_V	202_I	1.252	0.95
435_D	440_R	1.250	0.95
171_G	181_H	1.250	0.95
369_T	374_R	1.246	0.95
15_D	19_G	1.245	0.95
113_T	240_A	1.244	0.95
161_S	166_Q	1.239	0.95
267_L	284_F	1.235	0.95
168_A	205_V	1.231	0.95
14_L	17_L	1.227	0.95
338_D	374_R	1.225	0.95
280_E	296_Q	1.219	0.95
69_T	295_K	1.204	0.94
342_P	345_Q	1.197	0.94
169_R	205_V	1.192	0.94
392_R	421_K	1.173	0.93
396_A	399_I	1.163	0.93
148_A	151_A	1.159	0.93
10_L	13_T	1.155	0.93
99_T	181_H	1.150	0.93
148_A	154_D	1.147	0.93
119_W	122_S	1.146	0.92
27_D	75_V	1.146	0.92
26_E	30_K	1.141	0.92
330_M	334_M	1.137	0.92
210_R	237_D	1.135	0.92
32_V	56_I	1.135	0.92
302_E	307_E	1.132	0.92
331_R	377_E	1.128	0.92
190_A	226_Q	1.123	0.92
93_I	124_K	1.116	0.91
32_V	53_S	1.114	0.91
119_W	273_V	1.114	0.91
9_S	41_Q	1.102	0.91
331_R	335_Q	1.102	0.91
129_A	154_D	1.094	0.91
101_M	199_I	1.093	0.91
396_A	410_E	1.090	0.90
101_M	183_V	1.086	0.90
102_L	240_A	1.085	0.90
132_Q	158_E	1.072	0.90
201_E	205_V	1.071	0.90
335_Q	338_D	1.069	0.90
208_P	211_S	1.052	0.89
166_Q	169_R	1.051	0.89
385_E	389_A	1.051	0.89
12_G	16_T	1.050	0.89
119_W	276_I	1.049	0.89
59_R	64_E	1.049	0.89
146_E	149_D	1.045	0.89
63_E	67_G	1.041	0.88
193_D	197_A	1.039	0.88
172_L	206_V	1.039	0.88
16_T	30_K	1.028	0.88
136_F	198_E	1.028	0.88
371_E	375_G	1.028	0.88
222_G	226_Q	1.027	0.88
406_S	409_P	1.023	0.87
379_I	408_Q	1.022	0.87
119_W	151_A	1.022	0.87
282_D	295_K	1.021	0.87
108_S	114_A	1.020	0.87
113_T	276_I	1.015	0.87
32_V	75_V	1.010	0.87
15_D	20_K	1.008	0.87
193_D	233_S	1.004	0.86
162_D	166_Q	1.003	0.86
119_W	123_K	0.999	0.86
132_Q	141_Y	0.996	0.86
392_R	424_A	0.994	0.86
280_E	283_S	0.986	0.85
372_R	419_Q	0.975	0.85
217_A	244_L	0.974	0.85
253_S	264_I	0.970	0.84
235_G	262_S	0.969	0.84
55_S	258_N	0.969	0.84
195_L	199_I	0.946	0.83
165_V	172_L	0.945	0.83
379_I	403_A	0.944	0.83
168_A	172_L	0.940	0.83
315_W	318_E	0.939	0.83
100_I	180_V	0.932	0.82
33_K	37_R	0.931	0.82
327_L	393_S	0.929	0.82
321_M	431_Q	0.925	0.82
122_S	151_A	0.925	0.82
158_E	162_D	0.925	0.82
422_M	425_Q	0.923	0.81
342_P	346_V	0.920	0.81
94_P	209_D	0.918	0.81
95_L	98_Q	0.915	0.81
26_E	29_D	0.910	0.80
343_L	346_V	0.909	0.80
203_E	236_I	0.906	0.80
118_A	151_A	0.905	0.80
126_L	179_D	0.905	0.80
24_S	27_D	0.905	0.80
305_M	310_D	0.901	0.80
131_V	183_V	0.895	0.79
55_S	58_E	0.893	0.79
25_E	61_L	0.891	0.79
31_V	75_V	0.884	0.79
283_S	296_Q	0.883	0.78
334_M	423_M	0.881	0.78
226_Q	229_Q	0.880	0.78
369_T	372_R	0.877	0.78
318_E	322_K	0.875	0.78
330_M	376_F	0.871	0.77
298_T	302_E	0.869	0.77
23_I	75_V	0.867	0.77
300_R	303_R	0.867	0.77
122_S	149_D	0.864	0.77
159_P	162_D	0.859	0.77
129_A	181_H	0.859	0.77
91_T	280_E	0.858	0.76
60_S	78_I	0.851	0.76
81_E	295_K	0.849	0.76
129_A	176_A	0.847	0.75
35_I	75_V	0.846	0.75
228_R	231_D	0.845	0.75
132_Q	157_G	0.841	0.75
99_T	209_D	0.839	0.75
165_V	206_V	0.837	0.75
212_L	265_A	0.836	0.75
136_F	164_P	0.836	0.75
224_K	259_E	0.832	0.74
231_D	236_I	0.831	0.74
128_P	209_D	0.831	0.74
239_V	256_A	0.826	0.74
23_I	28_V	0.825	0.74
102_L	113_T	0.822	0.73
229_Q	232_A	0.821	0.73
102_L	268_G	0.820	0.73
89_D	257_V	0.820	0.73
244_L	269_S	0.819	0.73
357_L	361_L	0.818	0.73
399_I	414_R	0.816	0.73
282_D	286_S	0.815	0.73
408_Q	411_D	0.814	0.73
323_G	424_A	0.813	0.72
120_W	278_R	0.812	0.72
145_A	155_F	0.808	0.72
141_Y	159_P	0.808	0.72
28_V	75_V	0.807	0.72
308_T	314_D	0.806	0.72
101_M	211_S	0.804	0.72
141_Y	158_E	0.804	0.72
317_P	320_L	0.803	0.72
327_L	420_H	0.799	0.71
215_L	241_I	0.799	0.71
133_T	183_V	0.796	0.71
201_E	204_G	0.796	0.71
358_M	361_L	0.796	0.71
88_G	281_P	0.795	0.71
412_R	415_E	0.795	0.71
22_R	64_E	0.786	0.70
70_S	73_D	0.785	0.70
165_V	168_A	0.785	0.70
372_R	375_G	0.781	0.69
35_I	76_L	0.778	0.69
433_M	436_G	0.776	0.69
374_R	381_D	0.776	0.69
172_L	205_V	0.772	0.69
132_Q	155_F	0.771	0.68
142_E	160_D	0.767	0.68
390_D	393_S	0.765	0.68
145_A	159_P	0.764	0.68
142_E	159_P	0.764	0.68
90_S	93_I	0.761	0.67
347_M	361_L	0.761	0.67
108_S	217_A	0.760	0.67
374_R	377_E	0.759	0.67
36_Q	49_V	0.759	0.67
294_L	298_T	0.758	0.67
386_A	389_A	0.758	0.67
15_D	18_R	0.757	0.67
368_V	374_R	0.757	0.67
115_A	151_A	0.754	0.67
264_I	267_L	0.750	0.66
330_M	426_T	0.750	0.66
425_Q	429_Q	0.750	0.66
73_D	294_L	0.750	0.66
213_L	239_V	0.748	0.66
77_R	302_E	0.746	0.66
147_M	150_R	0.745	0.66
12_G	15_D	0.744	0.66
285_I	288_L	0.744	0.66
182_I	276_I	0.744	0.66
27_D	30_K	0.738	0.65
135_T	198_E	0.738	0.65
236_I	268_G	0.735	0.65
183_V	202_I	0.730	0.64
354_G	357_L	0.730	0.64
164_P	202_I	0.727	0.64
215_L	391_P	0.727	0.64
300_R	304_A	0.725	0.64
338_D	370_Q	0.723	0.63
369_T	375_G	0.723	0.63
421_K	424_A	0.722	0.63
316_D	320_L	0.722	0.63
150_R	275_D	0.720	0.63
237_D	262_S	0.718	0.63
415_E	419_Q	0.716	0.63
115_A	150_R	0.714	0.62
162_D	170_D	0.712	0.62
142_E	146_E	0.712	0.62
103_A	153_V	0.712	0.62
346_V	350_I	0.710	0.62
73_D	291_M	0.710	0.62
14_L	23_I	0.709	0.62
199_I	211_S	0.707	0.62
81_E	298_T	0.705	0.61
42_A	249_K	0.703	0.61
66_P	298_T	0.703	0.61
380_M	388_M	0.701	0.61
98_Q	126_L	0.701	0.61
168_A	183_V	0.699	0.61
372_R	423_M	0.694	0.60
372_R	412_R	0.692	0.60
62_E	65_P	0.689	0.60
135_T	158_E	0.689	0.60
316_D	319_D	0.687	0.59
14_L	21_S	0.687	0.59
336_A	340_M	0.686	0.59
354_G	358_M	0.686	0.59
435_D	439_Q	0.685	0.59
106_Q	189_H	0.684	0.59
132_Q	331_R	0.683	0.59
344_D	367_D	0.682	0.59
433_M	440_R	0.682	0.59
395_G	399_I	0.682	0.59
11_R	355_G	0.682	0.59
204_G	207_E	0.682	0.59
396_A	400_R	0.681	0.59
213_L	226_Q	0.681	0.59
340_M	346_V	0.680	0.59
66_P	81_E	0.677	0.58
323_G	431_Q	0.676	0.58
148_A	153_V	0.676	0.58
196_I	222_G	0.673	0.58
28_V	32_V	0.673	0.58
319_D	329_D	0.672	0.58
382_S	405_G	0.669	0.57
121_F	265_A	0.669	0.57
434_G	437_D	0.669	0.57
406_S	411_D	0.667	0.57
419_Q	422_M	0.667	0.57
2_V	159_P	0.666	0.57
269_S	300_R	0.664	0.57
50_M	54_E	0.664	0.57
207_E	237_D	0.664	0.57
433_M	437_D	0.663	0.57
86_L	237_D	0.660	0.56
23_I	31_V	0.659	0.56
157_G	162_D	0.659	0.56
14_L	72_R	0.658	0.56
424_A	428_Q	0.658	0.56
309_Q	339_N	0.657	0.56
89_D	92_P	0.657	0.56
299_E	302_E	0.657	0.56
72_R	76_L	0.656	0.56
35_I	87_V	0.656	0.56
342_P	350_I	0.654	0.56
33_K	50_M	0.653	0.56
347_M	350_I	0.652	0.56
9_S	36_Q	0.651	0.55
354_G	360_E	0.650	0.55
419_Q	423_M	0.648	0.55
300_R	345_Q	0.648	0.55
266_F	278_R	0.648	0.55
319_D	326_T	0.646	0.55
318_E	321_M	0.645	0.55
19_G	24_S	0.643	0.55
28_V	31_V	0.643	0.55
151_A	155_F	0.643	0.55
315_W	326_T	0.643	0.55
32_V	35_I	0.642	0.54
334_M	373_M	0.641	0.54
8_S	12_G	0.641	0.54
27_D	298_T	0.641	0.54
113_T	269_S	0.640	0.54
103_A	211_S	0.638	0.54
324_E	392_R	0.638	0.54
401_R	405_G	0.637	0.54
420_H	427_M	0.637	0.54
99_T	174_A	0.636	0.54
142_E	149_D	0.636	0.54
280_E	299_E	0.633	0.53
292_G	351_P	0.631	0.53
268_G	400_R	0.630	0.53
78_I	306_E	0.629	0.53
76_L	295_K	0.628	0.53
306_E	310_D	0.627	0.53
132_Q	209_D	0.626	0.53
130_I	144_A	0.626	0.53
417_L	420_H	0.626	0.53
130_I	154_D	0.622	0.52
328_H	381_D	0.621	0.52
196_I	218_A	0.620	0.52
269_S	277_E	0.619	0.52
125_G	157_G	0.614	0.51
158_E	161_S	0.614	0.51
302_E	305_M	0.614	0.51
102_L	117_M	0.613	0.51
163_D	171_G	0.613	0.51
66_P	74_H	0.612	0.51
57_T	61_L	0.610	0.51
410_E	414_R	0.609	0.51
421_K	425_Q	0.608	0.50
159_P	243_K	0.608	0.50
132_Q	148_A	0.607	0.50
141_Y	243_K	0.605	0.50
119_W	150_R	0.604	0.50
305_M	309_Q	0.603	0.50
300_R	409_P	0.603	0.50
63_E	308_T	0.602	0.50
128_P	179_D	0.602	0.50
157_G	160_D	0.600	0.50
66_P	69_T	0.599	0.49
112_T	268_G	0.599	0.49
295_K	302_E	0.597	0.49
132_Q	162_D	0.597	0.49
127_R	177_D	0.597	0.49
393_S	417_L	0.596	0.49
194_D	197_A	0.596	0.49
378_V	408_Q	0.595	0.49
158_E	167_I	0.595	0.49
199_I	226_Q	0.595	0.49
239_V	262_S	0.595	0.49
304_A	307_E	0.593	0.49
55_S	346_V	0.591	0.49
113_T	236_I	0.591	0.49
135_T	141_Y	0.590	0.48
330_M	345_Q	0.590	0.48
181_H	206_V	0.589	0.48
158_E	166_Q	0.588	0.48
199_I	229_Q	0.587	0.48
190_A	199_I	0.586	0.48
27_D	72_R	0.586	0.48
37_R	40_L	0.586	0.48
136_F	195_L	0.584	0.48
193_D	386_A	0.583	0.48
68_G	260_T	0.582	0.47
98_Q	132_Q	0.582	0.47
342_P	348_D	0.581	0.47
15_D	27_D	0.581	0.47
59_R	65_P	0.581	0.47
216_D	243_K	0.581	0.47
56_I	60_S	0.579	0.47
330_M	377_E	0.579	0.47
16_T	21_S	0.578	0.47
122_S	150_R	0.578	0.47
56_I	79_V	0.578	0.47
151_A	154_D	0.576	0.47
219_I	223_A	0.576	0.47
368_V	372_R	0.574	0.47
218_A	247_T	0.574	0.47
124_K	278_R	0.573	0.46
14_L	31_V	0.573	0.46
38_S	253_S	0.573	0.46
235_G	354_G	0.572	0.46
350_I	354_G	0.571	0.46
3_L	322_K	0.571	0.46
436_G	439_Q	0.570	0.46
165_V	239_V	0.567	0.46
77_R	219_I	0.565	0.46
195_L	268_G	0.565	0.46
56_I	319_D	0.565	0.46
165_V	169_R	0.564	0.45
328_H	331_R	0.564	0.45
145_A	148_A	0.564	0.45
95_L	174_A	0.563	0.45
87_V	284_F	0.563	0.45
330_M	424_A	0.562	0.45
366_M	369_T	0.560	0.45
202_I	205_V	0.559	0.45
212_L	406_S	0.558	0.45
106_Q	196_I	0.557	0.45
231_D	234_I	0.557	0.45
275_D	278_R	0.556	0.44
213_L	236_I	0.556	0.44
150_R	273_V	0.555	0.44
342_P	376_F	0.555	0.44
347_M	353_M	0.554	0.44
50_M	55_S	0.554	0.44
27_D	35_I	0.554	0.44
83_L	294_L	0.553	0.44
174_A	209_D	0.553	0.44
141_Y	157_G	0.553	0.44
9_S	14_L	0.552	0.44
344_D	348_D	0.552	0.44
70_S	290_G	0.552	0.44
337_M	350_I	0.551	0.44
114_A	118_A	0.550	0.44
324_E	424_A	0.549	0.44
3_L	7_G	0.548	0.44
156_Y	243_K	0.548	0.44
23_I	65_P	0.547	0.43
13_T	16_T	0.547	0.43
189_H	222_G	0.547	0.43
76_L	291_M	0.545	0.43
2_V	7_G	0.544	0.43
5_D	8_S	0.543	0.43
29_D	231_D	0.542	0.43
339_N	344_D	0.541	0.43
132_Q	284_F	0.541	0.43
199_I	228_R	0.541	0.43
174_A	197_A	0.540	0.43
191_L	196_I	0.540	0.43
65_P	78_I	0.539	0.43
37_R	41_Q	0.539	0.43
40_L	56_I	0.538	0.42
322_K	326_T	0.537	0.42
9_S	391_P	0.536	0.42
375_G	424_A	0.535	0.42
130_I	206_V	0.535	0.42
18_R	355_G	0.534	0.42
163_D	205_V	0.534	0.42
102_L	182_I	0.533	0.42
327_L	410_E	0.533	0.42
181_H	261_D	0.532	0.42
392_R	395_G	0.532	0.42
4_D	93_I	0.530	0.42
296_Q	299_E	0.529	0.41
133_T	381_D	0.529	0.41
46_V	50_M	0.528	0.41
81_E	302_E	0.528	0.41
91_T	120_W	0.527	0.41
75_V	277_E	0.527	0.41
257_V	261_D	0.526	0.41
39_L	49_V	0.525	0.41
185_T	291_M	0.525	0.41
372_R	415_E	0.525	0.41
145_A	160_D	0.525	0.41
69_T	74_H	0.525	0.41
92_P	265_A	0.524	0.41
183_V	205_V	0.524	0.41
160_D	163_D	0.523	0.41
346_V	375_G	0.523	0.41
23_I	79_V	0.523	0.41
63_E	78_I	0.522	0.41
348_D	358_M	0.522	0.41
69_T	147_M	0.521	0.41
156_Y	159_P	0.521	0.41
213_L	252_G	0.520	0.40
249_K	285_I	0.520	0.40
395_G	417_L	0.520	0.40
9_S	179_D	0.520	0.40
171_G	183_V	0.519	0.40
369_T	378_V	0.519	0.40
174_A	344_D	0.518	0.40
87_V	217_A	0.518	0.40
267_L	296_Q	0.518	0.40
194_D	389_A	0.518	0.40
113_T	260_T	0.517	0.40
150_R	272_T	0.517	0.40
361_L	366_M	0.517	0.40
69_T	282_D	0.517	0.40
74_H	298_T	0.517	0.40
69_T	73_D	0.517	0.40
395_G	402_I	0.516	0.40
141_Y	164_P	0.515	0.40
192_E	196_I	0.515	0.40
169_R	406_S	0.515	0.40
135_T	161_S	0.515	0.40
106_Q	218_A	0.514	0.40
333_Q	337_M	0.514	0.40
199_I	213_L	0.514	0.40
344_D	361_L	0.513	0.40
400_R	411_D	0.513	0.40
343_L	417_L	0.512	0.40
309_Q	314_D	0.511	0.39
314_D	321_M	0.511	0.39
175_T	232_A	0.511	0.39
199_I	268_G	0.511	0.39
5_D	330_M	0.511	0.39
354_G	359_D	0.511	0.39
372_R	376_F	0.510	0.39
337_M	376_F	0.510	0.39
266_F	406_S	0.510	0.39
410_E	428_Q	0.510	0.39
218_A	288_L	0.509	0.39
305_M	345_Q	0.508	0.39
428_Q	432_G	0.507	0.39
125_G	128_P	0.507	0.39
12_G	64_E	0.506	0.39
121_F	182_I	0.506	0.39
350_I	357_L	0.505	0.39
56_I	152_E	0.504	0.39
95_L	209_D	0.504	0.39
74_H	349_M	0.504	0.39
197_A	232_A	0.503	0.39
256_A	345_Q	0.503	0.39
197_A	233_S	0.503	0.39
250_G	260_T	0.503	0.39
291_M	295_K	0.502	0.38
189_H	199_I	0.502	0.38
141_Y	161_S	0.501	0.38
35_I	56_I	0.501	0.38
161_S	170_D	0.501	0.38
76_L	298_T	0.500	0.38

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2ffhA	4	0.8761	100	0.404	Contact Map
2v3cC	1	0.863	100	0.411	Contact Map
2xxaA	1	0.8804	100	0.414	Contact Map
2j37W	1	0.9652	100	0.422	Contact Map
3dm5A	4	0.8935	100	0.454	Contact Map
3kl4A	1	0.8783	100	0.462	Contact Map
4c7oA	1	0.6304	100	0.628	Contact Map
1ls1A	1	0.6196	100	0.642	Contact Map
2yhsA	1	0.6239	100	0.67	Contact Map
1vmaA	1	0.5957	100	0.67	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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