GREMLIN Database
PSTB2 - Phosphate import ATP-binding protein PstB 2
UniProt: Q9HML8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 345 (267)
Sequences: 18508 (11723)
Seq/√Len: 717.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
112_S308_Q4.7331.00
90_D103_S4.3461.00
87_S107_D3.8991.00
89_S146_R3.5841.00
88_V91_L3.4991.00
99_R102_E3.4731.00
109_P112_S3.2781.00
303_A325_D2.8651.00
322_D326_A2.7741.00
93_T130_C2.7321.00
92_D144_E2.6611.00
146_R153_D2.5661.00
167_Q260_D2.5441.00
323_A326_A2.5221.00
128_L295_V2.5021.00
114_T310_A2.4911.00
92_D103_S2.4851.00
89_S148_A2.4571.00
128_L263_L2.4311.00
88_V106_L2.4301.00
87_S148_A2.3781.00
115_A306_S2.3111.00
169_G259_P2.3051.00
108_I114_T2.3011.00
102_E317_R2.2821.00
93_T138_I2.2581.00
94_Y138_I2.2361.00
308_Q321_Y2.2151.00
106_L310_A2.2061.00
94_Y99_R2.1781.00
233_R236_D2.1381.00
92_D99_R2.1371.00
91_L137_R2.1351.00
185_N253_R2.1251.00
90_D105_S2.0021.00
183_R187_S1.9541.00
284_E304_R1.9501.00
294_V306_S1.8791.00
33_A37_S1.8641.00
28_S31_A1.8441.00
218_E222_R1.8161.00
93_T135_N1.7941.00
132_N263_L1.7891.00
115_A302_A1.7151.00
181_S184_D1.7041.00
258_D290_Y1.6731.00
129_R134_M1.6461.00
296_T302_A1.6101.00
180_K239_L1.5921.00
236_D240_G1.5361.00
34_A37_S1.4711.00
48_G51_G1.4511.00
132_N170_M1.4371.00
133_R136_D1.4291.00
184_D187_S1.4201.00
84_A148_A1.4201.00
86_V149_L1.4141.00
190_P193_H1.4101.00
61_A64_V1.4101.00
238_A249_L1.3931.00
89_S105_S1.3631.00
29_T32_A1.3451.00
101_L104_V1.3431.00
130_C137_R1.3401.00
85_K107_D1.3191.00
112_S307_D1.3191.00
84_A87_S1.3101.00
286_L290_Y1.3061.00
39_K42_G1.3031.00
185_N238_A1.2901.00
56_D59_A1.2861.00
310_A321_Y1.2791.00
325_D329_Q1.2641.00
237_N240_G1.2601.00
50_P53_V1.2561.00
129_R135_N1.2461.00
108_I291_T1.2321.00
114_T308_Q1.2191.00
88_V147_V1.2161.00
227_W232_D1.2141.00
169_G254_C1.2101.00
113_V306_S1.2001.00
314_T319_A1.1841.00
26_A29_T1.1831.00
127_F313_L1.1801.00
25_A29_T1.1691.00
47_P51_G1.1681.00
93_T126_T1.1641.00
216_L219_R1.1631.00
296_T301_Q1.1501.00
43_I46_P1.1491.00
280_E304_R1.1471.00
85_K110_A1.1461.00
28_S32_A1.1431.00
243_G248_R1.1421.00
29_T33_A1.1361.00
55_G59_A1.1361.00
326_A329_Q1.1341.00
92_D102_E1.1331.00
122_C313_L1.1321.00
116_L310_A1.1251.00
317_R321_Y1.0881.00
138_I144_E1.0861.00
116_L127_F1.0851.00
35_A39_K1.0731.00
180_K184_D1.0731.00
322_D327_I1.0721.00
168_V261_V1.0631.00
215_D219_R1.0561.00
271_L279_I1.0541.00
185_N188_Y1.0511.00
42_G45_G1.0491.00
189_G253_R1.0451.00
113_V294_V1.0441.00
220_A256_A1.0371.00
172_F175_P1.0371.00
95_Y100_A1.0361.00
32_A35_A1.0321.00
95_Y126_T1.0261.00
311_V327_I1.0251.00
276_T298_N1.0251.00
228_D232_D1.0231.00
111_E291_T1.0181.00
85_K109_P1.0121.00
62_R65_G1.0091.00
40_T53_V1.0071.00
49_G53_V1.0031.00
35_A43_I1.0001.00
181_S185_N0.9961.00
248_R271_L0.9911.00
277_A281_D0.9871.00
51_G54_D0.9861.00
35_A42_G0.9791.00
310_A318_L0.9781.00
309_T324_T0.9771.00
182_I185_N0.9771.00
56_D60_V0.9661.00
50_P54_D0.9651.00
110_A260_D0.9651.00
113_V292_V0.9611.00
47_P50_P0.9611.00
320_E330_N0.9591.00
27_G30_D0.9571.00
314_T317_R0.9541.00
214_R218_E0.9481.00
85_K150_D0.9471.00
326_A330_N0.9361.00
47_P52_E0.9321.00
324_T328_F0.9231.00
262_I290_Y0.9211.00
308_Q320_E0.9151.00
108_I293_V0.9091.00
39_K43_I0.9061.00
114_T293_V0.8981.00
190_P194_G0.8931.00
106_L127_F0.8891.00
132_N168_V0.8891.00
55_G58_P0.8881.00
320_E331_P0.8821.00
281_D285_E0.8781.00
130_C147_V0.8771.00
39_K45_G0.8751.00
37_S40_T0.8701.00
42_G46_P0.8681.00
91_L130_C0.8671.00
35_A41_G0.8631.00
38_S41_G0.8631.00
30_D34_A0.8611.00
53_V57_E0.8591.00
35_A48_G0.8591.00
283_I305_I0.8581.00
40_T43_I0.8531.00
125_S129_R0.8531.00
44_A49_G0.8501.00
117_I311_V0.8421.00
37_S41_G0.8391.00
92_D101_L0.8391.00
109_P308_Q0.8381.00
124_K266_E0.8341.00
57_E60_V0.8211.00
46_P51_G0.8211.00
40_T44_A0.8211.00
46_P49_G0.8211.00
130_C138_I0.8181.00
45_G48_G0.8121.00
26_A30_D0.8111.00
224_A252_A0.8101.00
41_G46_P0.8061.00
59_A62_R0.8051.00
86_V261_V0.8021.00
36_V40_T0.8011.00
119_P122_C0.8011.00
63_T66_E0.8001.00
263_L293_V0.7991.00
33_A36_V0.7951.00
54_D57_E0.7891.00
219_R222_R0.7881.00
264_M283_I0.7871.00
40_T46_P0.7851.00
83_D109_P0.7841.00
101_L130_C0.7801.00
149_L261_V0.7801.00
34_A38_S0.7751.00
103_S317_R0.7721.00
185_N189_G0.7721.00
145_G150_D0.7671.00
178_F185_N0.7641.00
61_A65_G0.7641.00
317_R320_E0.7631.00
66_E69_E0.7621.00
88_V131_L0.7541.00
91_L147_V0.7531.00
65_G68_D0.7501.00
83_D110_A0.7481.00
69_E72_Q0.7471.00
190_P256_A0.7461.00
72_Q75_W0.7441.00
217_V220_A0.7431.00
53_V56_D0.7431.00
35_A40_T0.7351.00
187_S190_P0.7341.00
52_E55_G0.7341.00
49_G52_E0.7321.00
241_L249_L0.7321.00
118_G124_K0.7281.00
46_P50_P0.7271.00
311_V314_T0.7251.00
43_I58_P0.7231.00
187_S191_R0.7221.00
183_R234_L0.7221.00
68_D71_L0.7191.00
36_V42_G0.7181.00
120_S275_A0.7141.00
90_D144_E0.7141.00
287_A292_V0.7141.00
46_P54_D0.7121.00
71_L75_W0.7091.00
77_D287_A0.7061.00
108_I112_S0.7021.00
186_I189_G0.7021.00
49_G54_D0.7011.00
218_E234_L0.6981.00
94_Y100_A0.6961.00
64_V67_S0.6951.00
42_G47_P0.6951.00
234_L241_L0.6911.00
84_A109_P0.6901.00
130_C135_N0.6881.00
219_R223_R0.6871.00
25_A32_A0.6871.00
280_E301_Q0.6831.00
318_L321_Y0.6781.00
234_L238_A0.6761.00
294_V302_A0.6741.00
35_A38_S0.6731.00
36_V39_K0.6711.00
135_N138_I0.6701.00
43_I47_P0.6691.00
171_V247_Q0.6651.00
183_R186_I0.6651.00
300_Q304_R0.6631.00
31_A34_A0.6621.00
71_L74_A0.6611.00
222_R227_W0.6601.00
137_R144_E0.6581.00
177_P246_Q0.6531.00
47_P53_V0.6531.00
137_R147_V0.6531.00
68_D72_Q0.6501.00
76_T79_E0.6501.00
131_L293_V0.6491.00
46_P53_V0.6491.00
32_A36_V0.6471.00
116_L293_V0.6461.00
183_R235_G0.6451.00
94_Y98_E0.6451.00
222_R228_D0.6441.00
175_P250_C0.6431.00
36_V45_G0.6431.00
119_P314_T0.6431.00
294_V301_Q0.6421.00
179_P239_L0.6421.00
45_G49_G0.6411.00
171_V264_M0.6401.00
38_S42_G0.6391.00
294_V305_I0.6371.00
302_A306_S0.6361.00
67_S70_Q0.6351.00
44_A48_G0.6351.00
84_A107_D0.6331.00
180_K237_N0.6301.00
48_G52_E0.6291.00
259_P286_L0.6281.00
45_G52_E0.6271.00
89_S107_D0.6261.00
32_A55_G0.6261.00
54_D58_P0.6251.00
43_I49_G0.6241.00
45_G51_G0.6231.00
313_L318_L0.6231.00
232_D235_G0.6231.00
104_V318_L0.6211.00
316_G319_A0.6191.00
41_G53_V0.6181.00
85_K291_T0.6171.00
36_V53_V0.6131.00
31_A35_A0.6131.00
95_Y135_N0.6111.00
37_S42_G0.6091.00
44_A50_P0.6091.00
64_V68_D0.6061.00
183_R217_V0.6061.00
121_G266_E0.6051.00
182_I188_Y0.6041.00
102_E316_G0.6021.00
84_A150_D0.6021.00
185_N190_P0.6011.00
68_D74_A0.5991.00
93_T96_G0.5961.00
113_V287_A0.5951.00
120_S248_R0.5921.00
25_A28_S0.5911.00
120_S266_E0.5871.00
44_A52_E0.5861.00
40_T45_G0.5851.00
99_R138_I0.5841.00
115_A309_T0.5831.00
136_D155_Y0.5821.00
44_A47_P0.5791.00
51_G55_G0.5791.00
131_L263_L0.5781.00
182_I226_L0.5771.00
84_A110_A0.5771.00
184_D188_Y0.5761.00
29_T35_A0.5721.00
128_L132_N0.5711.00
41_G45_G0.5691.00
117_I302_A0.5691.00
25_A59_A0.5661.00
92_D138_I0.5641.00
171_V175_P0.5631.00
93_T101_L0.5601.00
194_G216_L0.5581.00
32_A43_I0.5581.00
94_Y97_E0.5561.00
31_A36_V0.5561.00
28_S55_G0.5561.00
278_K281_D0.5551.00
42_G48_G0.5551.00
218_E221_L0.5531.00
183_R188_Y0.5511.00
177_P185_N0.5511.00
37_S43_I0.5501.00
43_I50_P0.5491.00
39_K48_G0.5481.00
66_E71_L0.5451.00
97_E100_A0.5441.00
69_E73_D0.5441.00
46_P52_E0.5431.00
63_T70_Q0.5431.00
30_D33_A0.5431.00
36_V43_I0.5421.00
42_G53_V0.5421.00
113_V283_I0.5391.00
43_I48_G0.5371.00
90_D93_T0.5361.00
86_V131_L0.5351.00
64_V69_E0.5351.00
39_K44_A0.5311.00
52_E56_D0.5291.00
283_I292_V0.5281.00
169_G173_Q0.5271.00
284_E305_I0.5261.00
63_T68_D0.5261.00
32_A37_S0.5261.00
315_G318_L0.5261.00
243_G270_A0.5251.00
35_A45_G0.5241.00
48_G53_V0.5221.00
60_V64_V0.5221.00
39_K46_P0.5221.00
38_S45_G0.5221.00
228_D233_R0.5211.00
186_I190_P0.5201.00
280_E300_Q0.5181.00
39_K47_P0.5171.00
66_E70_Q0.5171.00
32_A42_G0.5151.00
61_A67_S0.5151.00
76_T258_D0.5141.00
172_F176_N0.5121.00
280_E296_T0.5111.00
35_A52_E0.5111.00
187_S217_V0.5111.00
303_A328_F0.5091.00
52_E57_E0.5060.99
188_Y192_K0.5060.99
220_A252_A0.5050.99
25_A33_A0.5030.99
113_V284_E0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4f4cA 1 0.7797 100 0.248 Contact Map
4ry2A 2 0.7768 100 0.25 Contact Map
3tuiC 2 0.6899 100 0.266 Contact Map
4q9hA 1 0.8174 100 0.266 Contact Map
4a82A 2 0.8087 100 0.274 Contact Map
3nh6A 1 0.7884 100 0.277 Contact Map
4mrsA 2 0.8087 100 0.279 Contact Map
2yyzA 1 0.6812 100 0.281 Contact Map
3zdqA 2 0.7855 100 0.281 Contact Map
1g291 4 0.6957 100 0.282 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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