Q9HML6 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HML6 - Phosphate transporter permease

UniProt:	Q9HML6	Sequences: MMRRVKRTVAARVTDPVVGVARSAREYRSRTGDTAVAVQAVICGSLGAAFVAFLVGSQWTVFPAGVFLATTVVGWRREQAATGKAVTFLMTVGTVGVLALIVAFLLVRSVPAVEHMGVGLLGRTADPLWAARDGGVYSLAPMLVGTAITTCIATVIATPVGIAGAVFISEIAPPRVRDVVKPGIELMAGIPSITYGFIGLTVLNQYFYAEFRTPTIGSYLAAGAMIGVMALPTVVTISEDALAAVPESVKSGALAMGSTPWQTTKSVTLPAGLSGVSAGVLLGVGRAMGETMAATVMLTHTKGFPSPVFDVFSQYGETLTTVIAFEGGNASGVHMSALFAGGVVLFVTVMALSVGSQYVEWRMHRKLGGET	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	371 (283)
Sequences:	9555 (6447)
Seq/√Len:	383.2

ECOLI - POTH PSTC MALF PSTA YCJO MALG YDCU UGPA YCJP POTI UGPE POTB CYSW CYST POTC YDCV THIP YNJC MODB
BACSU - GANP MDXF YQGH AMYD YESQ YESP YTEP YQGI ARAP LPLB MDXG GANQ YURN LPLC YTCP YURM ARAQ AMYC YVGM SSUC
HALSA - Q9HML6 Q9HS11 Q9HP02 Q9HP01 Q9HMT4 Q9HHQ7 Q9HHQ6 Q9HS12 Q9HR05 Q9HPK3 Q9HML7
SULSO - Q97UF3 Q97YY3 Q97YY2 Q97UY9 Q97UZ0 Q97ZT7 Q97ZT6 Q97ZC1 Q97VC0 Q97UF4 Q97ZC2 Q97Z98

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
262_Q	266_S	4.715	1.00
109_S	130_A	4.635	1.00
253_A	263_T	3.907	1.00
152_I	223_G	3.900	1.00
259_T	262_Q	3.856	1.00
254_L	263_T	3.433	1.00
261_W	265_K	3.254	1.00
158_T	280_V	3.148	1.00
170_E	250_K	3.108	1.00
128_L	131_A	2.890	1.00
103_A	107_V	2.558	1.00
156_I	227_G	2.531	1.00
250_K	268_T	2.504	1.00
144_V	148_I	2.472	1.00
128_L	132_R	2.227	1.00
260_P	263_T	2.212	1.00
120_L	123_R	2.171	1.00
317_E	325_F	2.142	1.00
166_V	264_T	2.079	1.00
250_K	263_T	2.074	1.00
238_S	276_V	2.069	1.00
140_A	144_V	2.062	1.00
307_P	310_D	1.980	1.00
253_A	258_S	1.900	1.00
179_V	183_G	1.872	1.00
249_V	271_A	1.870	1.00
291_T	295_T	1.857	1.00
245_V	271_A	1.837	1.00
262_Q	265_K	1.815	1.00
162_I	238_S	1.804	1.00
208_Y	212_R	1.755	1.00
247_E	251_S	1.752	1.00
92_V	96_G	1.752	1.00
358_Y	361_W	1.739	1.00
326_E	334_H	1.725	1.00
239_E	243_A	1.682	1.00
151_C	155_V	1.670	1.00
322_V	341_G	1.669	1.00
162_I	264_T	1.669	1.00
241_A	275_G	1.669	1.00
106_L	343_V	1.650	1.00
218_S	221_A	1.639	1.00
169_S	243_A	1.634	1.00
253_A	267_V	1.621	1.00
150_T	284_V	1.617	1.00
322_V	326_E	1.611	1.00
131_A	135_G	1.577	1.00
269_L	276_V	1.566	1.00
141_P	144_V	1.556	1.00
165_A	238_S	1.534	1.00
169_S	239_E	1.525	1.00
81_A	85_A	1.525	1.00
181_K	239_E	1.519	1.00
160_V	231_L	1.517	1.00
88_F	92_V	1.515	1.00
141_P	145_G	1.509	1.00
231_L	235_V	1.507	1.00
278_A	282_L	1.476	1.00
161_G	234_V	1.472	1.00
242_L	268_T	1.470	1.00
109_S	343_V	1.465	1.00
83_G	87_T	1.451	1.00
193_I	296_V	1.449	1.00
351_A	355_G	1.447	1.00
119_G	122_G	1.439	1.00
355_G	358_Y	1.427	1.00
258_S	262_Q	1.427	1.00
169_S	242_L	1.406	1.00
249_V	267_V	1.406	1.00
147_A	151_C	1.384	1.00
100_L	104_F	1.379	1.00
298_L	316_G	1.377	1.00
142_M	322_V	1.365	1.00
116_M	119_G	1.359	1.00
217_G	220_L	1.354	1.00
241_A	272_G	1.352	1.00
85_A	88_F	1.347	1.00
152_I	156_I	1.339	1.00
174_P	177_R	1.331	1.00
354_V	358_Y	1.326	1.00
130_A	343_V	1.311	1.00
245_V	272_G	1.310	1.00
148_I	219_Y	1.307	1.00
323_I	341_G	1.306	1.00
164_G	235_V	1.300	1.00
78_E	81_A	1.298	1.00
168_I	235_V	1.298	1.00
149_T	318_T	1.286	1.00
155_V	159_P	1.285	1.00
245_V	250_K	1.284	1.00
162_I	272_G	1.284	1.00
154_T	280_V	1.280	1.00
107_V	111_P	1.276	1.00
317_E	321_T	1.265	1.00
220_L	224_A	1.258	1.00
218_S	316_G	1.257	1.00
238_S	279_G	1.243	1.00
129_W	132_R	1.243	1.00
219_Y	223_G	1.239	1.00
78_E	82_T	1.239	1.00
222_A	294_A	1.238	1.00
175_R	178_D	1.214	1.00
173_P	177_R	1.211	1.00
176_V	179_V	1.198	1.00
234_V	283_G	1.195	1.00
291_T	324_A	1.193	1.00
139_L	344_V	1.183	1.00
254_L	260_P	1.182	1.00
234_V	279_G	1.175	1.00
104_F	108_R	1.174	1.00
131_A	134_G	1.163	1.00
157_A	283_G	1.156	1.00
161_G	231_L	1.156	1.00
146_T	319_L	1.153	1.00
299_T	302_K	1.153	1.00
73_V	77_R	1.151	1.00
152_I	155_V	1.150	1.00
237_I	279_G	1.144	1.00
132_R	334_H	1.144	1.00
119_G	123_R	1.140	1.00
154_T	158_T	1.129	1.00
220_L	223_G	1.127	1.00
85_A	89_L	1.127	1.00
99_A	103_A	1.124	1.00
177_R	243_A	1.122	1.00
276_V	279_G	1.117	1.00
308_V	311_V	1.105	1.00
190_I	195_Y	1.102	1.00
219_Y	316_G	1.094	1.00
105_L	342_G	1.094	1.00
242_L	272_G	1.093	1.00
176_V	180_V	1.092	1.00
162_I	276_V	1.088	1.00
79_Q	82_T	1.076	1.00
290_E	294_A	1.073	1.00
185_E	236_T	1.072	1.00
80_A	83_G	1.070	1.00
206_Y	212_R	1.067	1.00
298_L	302_K	1.052	1.00
157_A	234_V	1.051	1.00
75_W	79_Q	1.049	1.00
295_T	321_T	1.045	1.00
74_G	77_R	1.044	1.00
133_D	337_A	1.042	1.00
307_P	311_V	1.036	1.00
283_G	286_R	1.035	1.00
188_A	233_T	1.035	1.00
358_Y	362_R	1.029	1.00
165_A	242_L	1.028	1.00
217_G	221_A	1.028	1.00
196_G	296_V	1.007	1.00
319_L	341_G	1.006	1.00
250_K	254_L	1.005	1.00
168_I	180_V	1.002	1.00
248_S	251_S	0.992	1.00
153_A	226_I	0.991	1.00
159_P	163_A	0.988	1.00
82_T	86_V	0.986	1.00
238_S	242_L	0.975	1.00
77_R	81_A	0.972	1.00
166_V	242_L	0.970	1.00
317_E	322_V	0.966	1.00
264_T	269_L	0.962	1.00
89_L	93_G	0.956	1.00
323_I	342_G	0.954	1.00
153_A	223_G	0.953	1.00
203_L	221_A	0.952	1.00
163_A	261_W	0.932	1.00
234_V	238_S	0.924	1.00
190_I	194_T	0.920	1.00
86_V	90_M	0.915	1.00
245_V	268_T	0.910	1.00
139_L	143_L	0.905	1.00
324_A	328_G	0.898	1.00
82_T	85_A	0.890	1.00
154_T	284_V	0.889	1.00
179_V	182_P	0.888	1.00
220_L	309_F	0.879	1.00
174_P	178_D	0.878	1.00
95_V	99_A	0.874	1.00
165_A	169_S	0.872	1.00
171_I	260_P	0.871	1.00
140_A	143_L	0.869	1.00
146_T	320_T	0.869	1.00
214_P	217_G	0.865	1.00
222_A	298_L	0.856	1.00
265_K	269_L	0.853	1.00
271_A	274_S	0.852	1.00
72_V	75_W	0.852	1.00
337_A	341_G	0.846	1.00
149_T	219_Y	0.842	1.00
258_S	263_T	0.839	1.00
123_R	131_A	0.838	1.00
216_I	220_L	0.837	1.00
136_V	337_A	0.837	1.00
223_G	227_G	0.836	1.00
214_P	218_S	0.833	1.00
95_V	100_L	0.829	1.00
334_H	337_A	0.827	1.00
139_L	341_G	0.823	1.00
144_V	147_A	0.821	1.00
104_F	107_V	0.820	1.00
221_A	297_M	0.812	1.00
291_T	294_A	0.811	1.00
272_G	276_V	0.810	1.00
199_G	225_M	0.807	1.00
142_M	319_L	0.806	1.00
279_G	283_G	0.805	1.00
158_T	238_S	0.804	1.00
292_M	296_V	0.802	1.00
175_R	179_V	0.800	1.00
77_R	80_A	0.798	1.00
107_V	110_V	0.797	1.00
118_V	122_G	0.792	1.00
157_A	230_A	0.788	1.00
153_A	287_A	0.787	1.00
247_E	254_L	0.787	1.00
327_G	338_L	0.787	1.00
163_A	167_F	0.786	1.00
173_P	176_V	0.785	1.00
68_L	71_T	0.783	1.00
67_F	70_T	0.782	1.00
225_M	297_M	0.782	1.00
161_G	238_S	0.782	1.00
259_T	263_T	0.780	1.00
199_G	297_M	0.773	1.00
266_S	271_A	0.772	1.00
320_T	345_L	0.772	1.00
158_T	276_V	0.770	1.00
263_T	266_S	0.762	1.00
318_T	321_T	0.762	1.00
260_P	264_T	0.761	1.00
166_V	269_L	0.758	1.00
138_S	141_P	0.757	1.00
161_G	235_V	0.755	1.00
69_A	72_V	0.747	1.00
225_M	293_A	0.745	1.00
70_T	74_G	0.742	1.00
143_L	319_L	0.739	1.00
91_T	95_V	0.738	1.00
285_G	352_L	0.738	1.00
192_S	229_M	0.734	1.00
252_G	267_V	0.733	1.00
188_A	232_P	0.732	1.00
204_N	221_A	0.731	1.00
118_V	123_R	0.730	1.00
288_M	349_V	0.729	1.00
74_G	81_A	0.729	1.00
72_V	76_R	0.728	1.00
252_G	255_A	0.725	1.00
132_R	136_V	0.723	1.00
76_R	80_A	0.720	1.00
156_I	160_V	0.716	1.00
80_A	84_K	0.716	1.00
69_A	73_V	0.705	1.00
273_L	277_S	0.703	1.00
81_A	84_K	0.703	1.00
129_W	133_D	0.701	1.00
115_H	333_V	0.700	1.00
73_V	76_R	0.699	0.99
233_T	237_I	0.699	0.99
157_A	226_I	0.690	0.99
347_V	351_A	0.690	0.99
79_Q	83_G	0.689	0.99
247_E	250_K	0.689	0.99
222_A	226_I	0.688	0.99
65_G	69_A	0.688	0.99
218_S	222_A	0.687	0.99
66_V	70_T	0.683	0.99
264_T	268_T	0.681	0.99
93_G	97_V	0.680	0.99
199_G	203_L	0.680	0.99
87_T	91_T	0.680	0.99
157_A	227_G	0.680	0.99
72_V	77_R	0.679	0.99
300_H	316_G	0.678	0.99
130_A	133_D	0.671	0.99
109_S	340_A	0.671	0.99
149_T	153_A	0.670	0.99
132_R	337_A	0.668	0.99
265_K	273_L	0.668	0.99
233_T	282_L	0.664	0.99
293_A	297_M	0.663	0.99
267_V	271_A	0.660	0.99
153_A	157_A	0.660	0.99
111_P	115_H	0.657	0.99
216_I	219_Y	0.657	0.99
351_A	354_V	0.656	0.99
273_L	276_V	0.655	0.99
301_T	316_G	0.655	0.99
145_G	219_Y	0.654	0.99
100_L	103_A	0.652	0.99
105_L	346_F	0.652	0.99
275_G	279_G	0.652	0.99
129_W	336_S	0.651	0.99
263_T	267_V	0.650	0.99
290_E	293_A	0.649	0.99
96_G	100_L	0.648	0.99
253_A	266_S	0.647	0.99
66_V	69_A	0.647	0.99
171_I	174_P	0.646	0.99
349_V	353_S	0.643	0.99
143_L	344_V	0.640	0.99
178_D	181_K	0.639	0.99
150_T	154_T	0.638	0.99
286_R	289_G	0.637	0.99
76_R	79_Q	0.635	0.99
298_L	301_T	0.634	0.99
156_I	223_G	0.633	0.99
261_W	264_T	0.631	0.99
226_I	290_E	0.630	0.99
290_E	318_T	0.629	0.99
149_T	226_I	0.629	0.99
141_P	317_E	0.629	0.99
292_M	297_M	0.627	0.99
189_G	195_Y	0.625	0.99
215_T	218_S	0.622	0.99
90_M	93_G	0.622	0.99
132_R	135_G	0.621	0.99
84_K	87_T	0.619	0.99
277_S	360_E	0.617	0.99
95_V	98_L	0.616	0.99
184_I	235_V	0.616	0.99
229_M	293_A	0.613	0.99
66_V	71_T	0.610	0.99
326_E	332_G	0.610	0.99
263_T	268_T	0.608	0.99
216_I	221_A	0.606	0.99
158_T	161_G	0.605	0.99
196_G	293_A	0.603	0.99
232_P	275_G	0.600	0.98
84_K	88_F	0.599	0.98
168_I	239_E	0.598	0.98
200_L	204_N	0.596	0.98
177_R	181_K	0.594	0.98
223_G	226_I	0.593	0.98
86_V	89_L	0.591	0.98
326_E	337_A	0.589	0.98
241_A	268_T	0.588	0.98
104_F	113_V	0.586	0.98
110_V	114_E	0.585	0.98
134_G	137_Y	0.585	0.98
154_T	287_A	0.585	0.98
213_T	217_G	0.584	0.98
188_A	229_M	0.580	0.98
170_E	268_T	0.578	0.98
102_V	106_L	0.578	0.98
152_I	308_V	0.578	0.98
337_A	344_V	0.575	0.98
282_L	286_R	0.574	0.98
196_G	199_G	0.573	0.98
74_G	78_E	0.572	0.98
319_L	345_L	0.572	0.98
355_G	359_V	0.571	0.98
321_T	325_F	0.571	0.98
272_G	275_G	0.570	0.98
207_F	212_R	0.570	0.98
112_A	340_A	0.568	0.98
117_G	123_R	0.568	0.98
156_I	159_P	0.567	0.98
133_D	341_G	0.566	0.98
88_F	91_T	0.565	0.98
146_T	288_M	0.563	0.98
332_G	335_M	0.559	0.98
197_F	200_L	0.559	0.98
192_S	292_M	0.556	0.98
71_T	75_W	0.556	0.98
300_H	317_E	0.555	0.97
123_R	128_L	0.555	0.97
226_I	293_A	0.554	0.97
221_A	225_M	0.554	0.97
164_G	231_L	0.552	0.97
185_E	188_A	0.552	0.97
168_I	181_K	0.549	0.97
344_V	348_T	0.548	0.97
191_P	292_M	0.548	0.97
300_H	325_F	0.546	0.97
195_Y	228_V	0.545	0.97
111_P	120_L	0.545	0.97
111_P	114_E	0.545	0.97
230_A	286_R	0.544	0.97
130_A	136_V	0.541	0.97
321_T	324_A	0.541	0.97
133_D	344_V	0.539	0.97
170_E	173_P	0.538	0.97
105_L	343_V	0.538	0.97
106_L	110_V	0.538	0.97
232_P	238_S	0.536	0.97
73_V	78_E	0.536	0.97
188_A	230_A	0.535	0.97
89_L	92_V	0.533	0.97
152_I	219_Y	0.531	0.97
241_A	271_A	0.531	0.97
339_F	342_G	0.531	0.97
230_A	283_G	0.529	0.97
167_F	171_I	0.528	0.97
241_A	245_V	0.528	0.97
123_R	129_W	0.527	0.97
178_D	243_A	0.525	0.96
320_T	323_I	0.524	0.96
250_K	260_P	0.523	0.96
293_A	296_V	0.522	0.96
325_F	331_S	0.522	0.96
356_S	360_E	0.521	0.96
246_P	251_S	0.520	0.96
238_S	275_G	0.517	0.96
76_R	81_A	0.515	0.96
203_L	225_M	0.515	0.96
71_T	77_R	0.514	0.96
323_I	338_L	0.514	0.96
164_G	184_I	0.514	0.96
118_V	121_L	0.514	0.96
195_Y	229_M	0.513	0.96
232_P	290_E	0.511	0.96
160_V	227_G	0.510	0.96
161_G	232_P	0.510	0.96
130_A	340_A	0.508	0.96
104_F	109_S	0.507	0.96
72_V	81_A	0.506	0.96
354_V	357_Q	0.504	0.96
188_A	191_P	0.501	0.95
190_I	293_A	0.500	0.95
294_A	298_L	0.500	0.95
101_I	109_S	0.500	0.95

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2onkC	2	0.6685	100	0.448	Contact Map
4tquM	1	0.7251	100	0.465	Contact Map
3rlfG	1	0.7332	100	0.474	Contact Map
3d31C	2	0.6523	100	0.476	Contact Map
4tquN	1	0.717	100	0.481	Contact Map
3rlfF	1	0.9137	100	0.498	Contact Map
4ymuD	2	0.5768	100	0.591	Contact Map
3tuiA	2	0.5633	100	0.611	Contact Map
2kogA	1	0.2426	31.4	0.954	Contact Map
3hd7A	1	0.2426	17.7	0.959	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0103 seconds.