SYFA - HALSA - GREMLIN Contacts

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SYFA - Phenylalanine--tRNA ligase alpha subunit

UniProt:	Q9HMK4	Sequences: MQLPTQQVAVLDAASTDDPQRIEALAADTDYPPETIAGAALALEAEGLVAVTETTTTTVSLTDEGHAYATDGLPEVRLYRAALDAGADDAPVEMGSVIGAAGLDGPQVDIALSNYARKGYGTIDSGALAADPDADPENDPEADALATLTDGDSVDDDAVVDQLASRDLVTVSERTVRSVTLTEAGVTELMAGVEATDEVGELTPELLASGEWADVEFADYNVAADAADHTPGKTHVLRQAAERVTDVLVGMGFQEMAGPHVDADFYINDCLFMPQDHPARNHWDRFALSNPARIDELPDALVERVERAHREGAGDDGDGYHSPWDEDFARALALRGHTTSLTARHLAGLADADVEAPARYFSVEKAYRNDTLDATHLLEFFQIEGWVLADDLSVRDLMGTFREFYSQFGIHDLQFKPTYNPYTEPSFELFGRHPETGELIEIGNSGIFRPEMLDPLDVDGDVMAWGLALERLLMLMTGFEDIRDVHGTLCDVGFLRNAEVVY	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	502 (474)
Sequences:	603 (401)
Seq/√Len:	18.4

HALSA - SYFA
SULSO - SYFA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
76_V	137_E	5.352	1.00
432_R	437_G	4.821	1.00
67_A	71_D	4.163	1.00
206_L	211_E	3.968	1.00
63_D	66_H	3.744	1.00
196_T	216_E	3.707	1.00
273_M	283_W	3.483	1.00
182_T	185_G	3.082	0.99
303_E	306_E	2.916	0.99
68_Y	74_P	2.884	0.99
308_A	315_D	2.760	0.98
57_T	171_V	2.760	0.98
412_D	434_P	2.756	0.98
301_L	456_L	2.752	0.98
299_D	303_E	2.727	0.98
391_D	461_D	2.717	0.98
324_W	329_A	2.661	0.98
297_L	302_V	2.620	0.97
283_W	333_A	2.495	0.96
418_T	430_F	2.477	0.96
412_D	439_L	2.477	0.96
66_H	149_T	2.474	0.96
493_G	497_N	2.446	0.96
447_I	453_L	2.420	0.96
410_I	431_G	2.406	0.96
50_A	182_T	2.402	0.96
93_E	96_S	2.338	0.95
427_F	445_S	2.304	0.94
119_G	133_D	2.224	0.93
454_D	460_G	2.223	0.93
394_V	445_S	2.222	0.93
307_R	311_E	2.168	0.92
431_G	434_P	2.159	0.92
312_G	319_G	2.157	0.92
365_K	486_H	2.151	0.92
434_P	437_G	2.143	0.92
486_H	495_L	2.142	0.92
285_R	370_D	2.131	0.92
390_D	461_D	2.120	0.91
405_Y	422_Y	2.116	0.91
443_G	467_L	2.111	0.91
66_H	70_T	2.079	0.91
420_N	444_N	2.075	0.91
474_M	482_I	2.050	0.90
264_D	287_A	2.025	0.89
392_L	463_M	2.013	0.89
151_G	154_V	1.993	0.89
287_A	370_D	1.983	0.88
237_L	470_E	1.960	0.88
65_G	69_A	1.945	0.87
310_R	323_P	1.939	0.87
82_A	121_G	1.933	0.87
251_M	419_Y	1.884	0.86
268_N	273_M	1.872	0.85
318_D	321_H	1.790	0.83
237_L	362_S	1.789	0.82
422_Y	470_E	1.769	0.82
248_L	434_P	1.767	0.82
282_H	287_A	1.765	0.82
169_V	391_D	1.759	0.81
40_A	51_V	1.752	0.81
237_L	477_T	1.747	0.81
429_L	443_G	1.728	0.80
362_S	384_E	1.727	0.80
414_Q	439_L	1.719	0.80
243_R	476_M	1.713	0.80
125_S	128_L	1.707	0.79
179_V	383_I	1.698	0.79
187_T	193_V	1.684	0.78
94_M	391_D	1.668	0.78
115_Y	120_Y	1.666	0.78
114_N	117_R	1.652	0.77
67_A	77_R	1.649	0.77
391_D	418_T	1.647	0.77
204_P	208_A	1.636	0.76
223_A	491_D	1.635	0.76
74_P	121_G	1.633	0.76
234_T	239_Q	1.630	0.76
221_N	375_T	1.622	0.76
401_F	429_L	1.619	0.76
250_G	407_Q	1.616	0.75
416_K	430_F	1.607	0.75
328_F	331_A	1.602	0.75
387_V	455_P	1.599	0.75
264_D	331_A	1.589	0.74
473_L	485_V	1.587	0.74
264_D	333_A	1.587	0.74
64_E	168_L	1.584	0.74
401_F	408_F	1.584	0.74
423_T	426_S	1.550	0.72
210_G	213_A	1.532	0.71
293_R	330_R	1.524	0.71
10_V	69_A	1.521	0.71
357_P	389_A	1.520	0.71
112_L	116_A	1.512	0.70
78_L	111_A	1.508	0.70
37_A	41_L	1.500	0.70
312_G	317_G	1.494	0.69
384_E	422_Y	1.490	0.69
96_S	326_E	1.489	0.69
420_N	428_E	1.484	0.69
416_K	420_N	1.476	0.68
59_V	160_V	1.475	0.68
237_L	377_L	1.471	0.68
115_Y	121_G	1.467	0.68
412_D	432_R	1.464	0.68
470_E	477_T	1.461	0.68
212_W	217_F	1.458	0.67
257_A	345_H	1.450	0.67
199_V	215_V	1.442	0.67
336_G	370_D	1.441	0.66
144_A	147_T	1.438	0.66
116_A	123_I	1.436	0.66
393_S	396_D	1.435	0.66
285_R	336_G	1.434	0.66
354_V	383_I	1.430	0.66
422_Y	443_G	1.423	0.65
333_A	401_F	1.415	0.65
411_H	434_P	1.409	0.65
436_T	440_I	1.408	0.65
145_L	151_G	1.399	0.64
453_L	482_I	1.387	0.63
82_A	127_A	1.384	0.63
264_D	332_L	1.381	0.63
210_G	478_G	1.378	0.63
81_A	98_I	1.377	0.63
265_F	305_V	1.362	0.62
258_G	341_L	1.353	0.61
439_L	485_V	1.349	0.61
396_D	399_G	1.346	0.61
240_A	473_L	1.343	0.61
343_A	452_M	1.340	0.61
416_K	428_E	1.336	0.60
64_E	68_Y	1.335	0.60
389_A	393_S	1.333	0.60
372_L	378_L	1.325	0.60
337_H	422_Y	1.319	0.59
52_T	180_T	1.317	0.59
268_N	364_E	1.312	0.59
264_D	422_Y	1.296	0.58
264_D	285_R	1.295	0.58
302_V	324_W	1.290	0.58
60_S	172_S	1.289	0.58
473_L	479_F	1.287	0.57
283_W	287_A	1.283	0.57
237_L	369_N	1.282	0.57
125_S	129_A	1.279	0.57
70_T	143_D	1.271	0.56
398_M	429_L	1.261	0.56
299_D	326_E	1.260	0.56
256_M	342_T	1.260	0.56
7_Q	74_P	1.260	0.56
77_R	107_Q	1.257	0.56
378_L	416_K	1.253	0.55
399_G	439_L	1.253	0.55
244_V	468_A	1.250	0.55
369_N	487_G	1.249	0.55
59_V	171_V	1.248	0.55
480_E	486_H	1.247	0.55
285_R	328_F	1.244	0.55
377_L	470_E	1.232	0.54
467_L	490_C	1.230	0.54
41_L	287_A	1.227	0.54
256_M	420_N	1.227	0.54
401_F	418_T	1.216	0.53
302_V	326_E	1.212	0.53
273_M	282_H	1.208	0.53
283_W	337_H	1.207	0.53
344_R	348_G	1.206	0.52
444_N	487_G	1.202	0.52
359_R	497_N	1.201	0.52
147_T	152_D	1.198	0.52
362_S	470_E	1.198	0.52
381_F	470_E	1.198	0.52
256_M	362_S	1.195	0.52
146_A	150_D	1.193	0.52
70_T	155_D	1.188	0.51
211_E	214_D	1.187	0.51
422_Y	467_L	1.168	0.50
329_A	464_A	1.167	0.50
444_N	461_D	1.164	0.50
455_P	467_L	1.163	0.50
10_V	39_A	1.163	0.50
420_N	487_G	1.160	0.50
237_L	383_I	1.159	0.50
481_D	484_D	1.153	0.49
266_Y	370_D	1.151	0.49
149_T	155_D	1.151	0.49
143_D	147_T	1.149	0.49
236_V	384_E	1.142	0.48
181_L	219_D	1.139	0.48
237_L	427_F	1.139	0.48
181_L	227_A	1.137	0.48
122_T	325_D	1.136	0.48
273_M	341_L	1.136	0.48
320_Y	490_C	1.135	0.48
278_P	425_P	1.131	0.48
248_L	342_T	1.131	0.48
8_V	12_D	1.116	0.47
65_G	331_A	1.114	0.47
274_P	404_F	1.112	0.47
142_A	146_A	1.111	0.47
291_P	342_T	1.111	0.47
413_L	477_T	1.107	0.46
65_G	154_V	1.107	0.46
248_L	422_Y	1.106	0.46
447_I	463_M	1.103	0.46
212_W	279_A	1.103	0.46
32_P	35_T	1.100	0.46
236_V	274_P	1.099	0.46
283_W	370_D	1.099	0.46
273_M	329_A	1.095	0.46
147_T	155_D	1.094	0.46
117_R	130_A	1.086	0.45
387_V	463_M	1.078	0.45
325_D	330_R	1.078	0.45
143_D	150_D	1.070	0.44
272_F	455_P	1.067	0.44
82_A	281_N	1.062	0.44
81_A	85_A	1.058	0.43
109_D	113_S	1.057	0.43
218_A	367_Y	1.056	0.43
396_D	463_M	1.055	0.43
83_L	87_A	1.048	0.43
109_D	442_I	1.047	0.43
78_L	113_S	1.042	0.42
470_E	487_G	1.040	0.42
118_K	288_L	1.036	0.42
162_Q	165_S	1.034	0.42
12_D	16_T	1.029	0.42
337_H	369_N	1.028	0.41
123_I	126_G	1.020	0.41
92_V	96_S	1.020	0.41
459_D	473_L	1.019	0.41
264_D	328_F	1.017	0.41
43_L	195_A	1.015	0.41
49_V	124_D	1.014	0.41
422_Y	487_G	1.013	0.41
450_P	482_I	1.010	0.40
278_P	465_W	1.008	0.40
14_A	243_R	1.005	0.40
69_A	146_A	1.002	0.40
283_W	336_G	0.996	0.40
77_R	288_L	0.996	0.40
114_N	118_K	0.995	0.40
431_G	440_I	0.990	0.39
420_N	468_A	0.986	0.39
365_K	414_Q	0.986	0.39
298_P	455_P	0.983	0.39
268_N	285_R	0.982	0.39
243_R	383_I	0.979	0.39
109_D	251_M	0.978	0.39
444_N	453_L	0.977	0.38
362_S	422_Y	0.976	0.38
209_S	215_V	0.976	0.38
394_V	398_M	0.974	0.38
47_G	393_S	0.973	0.38
74_P	109_D	0.972	0.38
418_T	453_L	0.971	0.38
264_D	370_D	0.967	0.38
369_N	420_N	0.967	0.38
283_W	422_Y	0.965	0.38
420_N	445_S	0.957	0.37
112_L	123_I	0.956	0.37
331_A	438_E	0.955	0.37
80_R	136_P	0.954	0.37
233_K	283_W	0.951	0.37
371_T	463_M	0.947	0.37
74_P	114_N	0.943	0.36
427_F	470_E	0.940	0.36
11_L	43_L	0.937	0.36
445_S	470_E	0.937	0.36
27_A	85_A	0.937	0.36
416_K	445_S	0.936	0.36
63_D	180_T	0.935	0.36
13_A	17_D	0.933	0.36
369_N	398_M	0.933	0.36
65_G	157_D	0.931	0.36
405_Y	470_E	0.928	0.36
364_E	370_D	0.925	0.35
117_R	229_H	0.925	0.35
198_E	390_D	0.924	0.35
49_V	347_A	0.923	0.35
241_A	405_Y	0.922	0.35
57_T	157_D	0.922	0.35
273_M	427_F	0.920	0.35
316_D	319_G	0.919	0.35
163_L	181_L	0.917	0.35
62_T	172_S	0.917	0.35
22_I	40_A	0.915	0.35
64_E	111_A	0.914	0.35
236_V	404_F	0.912	0.35
330_R	462_V	0.909	0.35
282_H	336_G	0.909	0.35
158_A	165_S	0.908	0.34
237_L	384_E	0.905	0.34
149_T	390_D	0.903	0.34
85_A	329_A	0.902	0.34
240_A	422_Y	0.900	0.34
139_D	184_A	0.898	0.34
472_L	495_L	0.896	0.34
345_H	465_W	0.888	0.33
264_D	337_H	0.887	0.33
383_I	470_E	0.887	0.33
74_P	78_L	0.886	0.33
254_Q	360_Y	0.882	0.33
80_R	84_D	0.874	0.33
355_E	462_V	0.873	0.33
268_N	432_R	0.872	0.32
248_L	283_W	0.872	0.32
26_A	33_P	0.872	0.32
148_L	169_V	0.870	0.32
410_I	416_K	0.869	0.32
394_V	427_F	0.866	0.32
268_N	369_N	0.865	0.32
221_N	226_A	0.863	0.32
16_T	214_D	0.861	0.32
236_V	336_G	0.860	0.32
81_A	307_R	0.859	0.32
113_S	116_A	0.859	0.32
147_T	151_G	0.854	0.31
475_L	482_I	0.853	0.31
41_L	44_E	0.850	0.31
369_N	377_L	0.850	0.31
240_A	405_Y	0.849	0.31
219_D	401_F	0.844	0.31
237_L	422_Y	0.843	0.31
427_F	469_L	0.842	0.31
312_G	316_D	0.842	0.31
442_I	464_A	0.842	0.31
234_T	395_R	0.841	0.31
369_N	477_T	0.839	0.31
383_I	422_Y	0.835	0.30
237_L	469_L	0.833	0.30
392_L	481_D	0.832	0.30
63_D	211_E	0.831	0.30
433_H	444_N	0.830	0.30
442_I	479_F	0.824	0.30
398_M	427_F	0.823	0.30
119_G	399_G	0.823	0.30
464_A	500_V	0.823	0.30
259_P	442_I	0.822	0.30
384_E	404_F	0.820	0.30
369_N	422_Y	0.819	0.30
278_P	424_E	0.816	0.29
115_Y	440_I	0.814	0.29
55_T	175_T	0.814	0.29
304_R	455_P	0.811	0.29
54_T	180_T	0.811	0.29
113_S	324_W	0.808	0.29
225_D	242_E	0.808	0.29
78_L	94_M	0.801	0.29
88_D	128_L	0.801	0.29
267_I	273_M	0.800	0.29
94_M	97_V	0.797	0.29
416_K	444_N	0.796	0.28
16_T	143_D	0.795	0.28
108_V	250_G	0.795	0.28
398_M	445_S	0.793	0.28
273_M	340_S	0.791	0.28
82_A	105_G	0.788	0.28
310_R	318_D	0.786	0.28
227_A	491_D	0.786	0.28
392_L	431_G	0.785	0.28
96_S	146_A	0.784	0.28
262_D	344_R	0.782	0.28
260_H	365_K	0.782	0.28
17_D	47_G	0.779	0.28
482_I	492_V	0.777	0.28
93_E	97_V	0.775	0.27
233_K	464_A	0.772	0.27
435_E	440_I	0.768	0.27
149_T	153_S	0.767	0.27
355_E	359_R	0.765	0.27
404_F	448_F	0.765	0.27
369_N	470_E	0.765	0.27
257_A	364_E	0.762	0.27
247_V	370_D	0.761	0.27
453_L	470_E	0.758	0.27
411_H	414_Q	0.756	0.26
50_A	71_D	0.755	0.26
139_D	142_A	0.753	0.26
246_D	465_W	0.753	0.26
262_D	273_M	0.749	0.26
370_D	422_Y	0.748	0.26
67_A	200_G	0.747	0.26
52_T	142_A	0.741	0.26
71_D	216_E	0.740	0.26
62_T	105_G	0.736	0.26
283_W	344_R	0.736	0.26
363_V	469_L	0.736	0.26
198_E	216_E	0.735	0.25
450_P	470_E	0.735	0.25
80_R	142_A	0.734	0.25
73_L	394_V	0.734	0.25
7_Q	114_N	0.734	0.25
373_D	376_H	0.732	0.25
337_H	362_S	0.731	0.25
42_A	343_A	0.731	0.25
337_H	379_E	0.730	0.25
455_P	484_D	0.730	0.25
237_L	248_L	0.729	0.25
219_D	484_D	0.727	0.25
443_G	448_F	0.724	0.25
408_F	429_L	0.724	0.25
143_D	155_D	0.724	0.25
122_T	186_V	0.723	0.25
247_V	338_T	0.723	0.25
276_D	473_L	0.722	0.25
429_L	445_S	0.722	0.25
213_A	304_R	0.721	0.25
369_N	444_N	0.721	0.25
110_I	168_L	0.720	0.25
154_V	213_A	0.719	0.25
244_V	469_L	0.719	0.25
201_E	413_L	0.715	0.25
241_A	320_Y	0.714	0.25
180_T	289_S	0.713	0.24
272_F	314_G	0.710	0.24
18_D	58_T	0.709	0.24
298_P	478_G	0.709	0.24
418_T	428_E	0.708	0.24
337_H	404_F	0.707	0.24
283_W	341_L	0.706	0.24
161_D	407_Q	0.706	0.24
435_E	491_D	0.705	0.24
69_A	142_A	0.705	0.24
294_I	330_R	0.703	0.24
77_R	82_A	0.703	0.24
147_T	154_V	0.702	0.24
237_L	241_A	0.700	0.24
386_W	420_N	0.700	0.24
418_T	482_I	0.699	0.24
287_A	463_M	0.697	0.24
256_M	443_G	0.697	0.24
263_A	294_I	0.697	0.24
416_K	487_G	0.696	0.24
5_T	396_D	0.694	0.24
104_D	108_V	0.693	0.24
311_E	315_D	0.692	0.24
466_G	471_R	0.692	0.24
107_Q	205_E	0.692	0.24
243_R	333_A	0.692	0.24
232_G	343_A	0.691	0.23
431_G	494_F	0.691	0.23
226_A	237_L	0.690	0.23
80_R	216_E	0.690	0.23
387_V	400_T	0.690	0.23
118_K	163_L	0.689	0.23
406_S	411_H	0.688	0.23
76_V	80_R	0.686	0.23
63_D	214_D	0.685	0.23
378_L	394_V	0.684	0.23
379_E	474_M	0.684	0.23
86_G	89_D	0.682	0.23
140_P	153_S	0.682	0.23
444_N	468_A	0.681	0.23
151_G	161_D	0.680	0.23
30_D	67_A	0.680	0.23
227_A	411_H	0.679	0.23
33_P	41_L	0.679	0.23
138_N	143_D	0.678	0.23
369_N	378_L	0.676	0.23
369_N	469_L	0.676	0.23
164_A	306_E	0.675	0.23
397_L	483_R	0.675	0.23
285_R	333_A	0.673	0.23
341_L	344_R	0.672	0.23
12_D	154_V	0.671	0.23
404_F	422_Y	0.671	0.23
33_P	332_L	0.671	0.23
138_N	153_S	0.670	0.23
329_A	401_F	0.667	0.22
38_G	59_V	0.667	0.22
431_G	461_D	0.667	0.22
108_V	118_K	0.665	0.22
14_A	20_Q	0.664	0.22
422_Y	444_N	0.664	0.22
424_E	465_W	0.663	0.22
327_D	330_R	0.663	0.22
445_S	477_T	0.662	0.22
184_A	241_A	0.662	0.22
68_Y	464_A	0.662	0.22
21_R	70_T	0.662	0.22
359_R	432_R	0.662	0.22
207_L	212_W	0.659	0.22
256_M	422_Y	0.658	0.22
433_H	487_G	0.658	0.22
14_A	18_D	0.656	0.22
146_A	211_E	0.656	0.22
78_L	198_E	0.655	0.22
381_F	475_L	0.655	0.22
44_E	49_V	0.654	0.22
262_D	267_I	0.653	0.22
94_M	307_R	0.651	0.22
36_I	410_I	0.651	0.22
248_L	370_D	0.650	0.22
62_T	143_D	0.650	0.22
387_V	496_R	0.649	0.22
369_N	416_K	0.648	0.22
336_G	422_Y	0.648	0.22
274_P	337_H	0.647	0.22
341_L	390_D	0.646	0.22
394_V	477_T	0.645	0.21
48_L	185_G	0.645	0.21
291_P	357_P	0.644	0.21
49_V	299_D	0.644	0.21
82_A	145_L	0.644	0.21
402_R	495_L	0.644	0.21
176_V	398_M	0.643	0.21
95_G	105_G	0.640	0.21
133_D	299_D	0.639	0.21
10_V	98_I	0.638	0.21
48_L	193_V	0.638	0.21
19_P	50_A	0.637	0.21
61_L	205_E	0.637	0.21
265_F	359_R	0.636	0.21
294_I	297_L	0.636	0.21
369_N	427_F	0.636	0.21
283_W	405_Y	0.636	0.21
307_R	314_G	0.636	0.21
264_D	273_M	0.634	0.21
416_K	482_I	0.633	0.21
114_N	199_V	0.632	0.21
31_Y	35_T	0.632	0.21
84_D	308_A	0.632	0.21
442_I	453_L	0.631	0.21
450_P	453_L	0.631	0.21
398_M	439_L	0.629	0.21
139_D	145_L	0.626	0.21
169_V	180_T	0.626	0.21
74_P	486_H	0.625	0.21
337_H	405_Y	0.625	0.21
369_N	394_V	0.625	0.21
240_A	487_G	0.624	0.21
251_M	337_H	0.624	0.21
184_A	187_T	0.623	0.21
235_H	336_G	0.622	0.21
109_D	401_F	0.622	0.21
259_P	341_L	0.622	0.21
144_A	158_A	0.622	0.21
207_L	306_E	0.621	0.20
248_L	486_H	0.617	0.20
428_E	482_I	0.617	0.20
82_A	107_Q	0.616	0.20
22_I	181_L	0.615	0.20
104_D	207_L	0.615	0.20
413_L	473_L	0.614	0.20
20_Q	181_L	0.613	0.20
10_V	14_A	0.612	0.20
256_M	384_E	0.612	0.20
26_A	123_I	0.611	0.20
288_L	295_D	0.610	0.20
287_A	332_L	0.609	0.20
26_A	37_A	0.609	0.20
65_G	171_V	0.606	0.20
452_M	455_P	0.606	0.20
377_L	405_Y	0.605	0.20
289_S	371_T	0.605	0.20
96_S	140_P	0.605	0.20
69_A	210_G	0.604	0.20
249_V	333_A	0.604	0.20
118_K	403_E	0.604	0.20
441_E	446_G	0.603	0.20
337_H	470_E	0.603	0.20
256_M	262_D	0.602	0.20
258_G	345_H	0.601	0.20
237_L	337_H	0.600	0.20
153_S	181_L	0.599	0.20
266_Y	285_R	0.599	0.20
163_L	168_L	0.598	0.20
316_D	499_E	0.598	0.20
155_D	159_V	0.598	0.20
369_N	404_F	0.598	0.20
306_E	327_D	0.597	0.20
69_A	76_V	0.597	0.20
300_A	304_R	0.595	0.19
172_S	242_E	0.595	0.19
10_V	15_S	0.595	0.19
282_H	331_A	0.594	0.19
67_A	155_D	0.593	0.19
264_D	336_G	0.593	0.19
24_A	135_D	0.592	0.19
366_A	379_E	0.591	0.19
14_A	98_I	0.591	0.19
49_V	406_S	0.590	0.19
117_R	169_V	0.590	0.19
308_A	316_D	0.589	0.19
73_L	276_D	0.588	0.19
217_F	256_M	0.587	0.19
267_I	283_W	0.586	0.19
273_M	332_L	0.584	0.19
451_E	466_G	0.584	0.19
79_Y	224_A	0.582	0.19
430_F	433_H	0.579	0.19
20_Q	80_R	0.579	0.19
245_T	370_D	0.578	0.19
75_E	168_L	0.578	0.19
135_D	391_D	0.578	0.19
282_H	337_H	0.578	0.19
7_Q	444_N	0.577	0.19
378_L	420_N	0.577	0.19
25_L	53_E	0.576	0.19
430_F	442_I	0.576	0.19
93_E	185_G	0.575	0.19
150_D	182_T	0.575	0.19
78_L	131_D	0.575	0.19
390_D	468_A	0.574	0.19
420_N	430_F	0.574	0.19
161_D	304_R	0.573	0.19
420_N	452_M	0.573	0.19
70_T	158_A	0.573	0.19
126_G	169_V	0.572	0.19
82_A	106_P	0.571	0.19
145_L	148_L	0.571	0.19
264_D	270_C	0.571	0.19
362_S	383_I	0.571	0.19
372_L	396_D	0.568	0.18
374_A	494_F	0.568	0.18
97_V	325_D	0.567	0.18
42_A	444_N	0.567	0.18
207_L	299_D	0.562	0.18
213_A	438_E	0.561	0.18
290_N	440_I	0.561	0.18
329_A	500_V	0.561	0.18
286_F	337_H	0.561	0.18
198_E	300_A	0.560	0.18
44_E	314_G	0.559	0.18
64_E	110_I	0.558	0.18
164_A	287_A	0.558	0.18
285_R	364_E	0.557	0.18
384_E	443_G	0.557	0.18
128_L	329_A	0.556	0.18
61_L	149_T	0.555	0.18
262_D	283_W	0.555	0.18
108_V	491_D	0.554	0.18
11_L	15_S	0.553	0.18
202_L	210_G	0.551	0.18
200_G	459_D	0.551	0.18
285_R	337_H	0.551	0.18
113_S	161_D	0.550	0.18
420_N	431_G	0.550	0.18
384_E	455_P	0.549	0.18
244_V	381_F	0.548	0.18
169_V	177_R	0.548	0.18
74_P	107_Q	0.548	0.18
199_V	206_L	0.548	0.18
222_V	234_T	0.546	0.18
202_L	346_L	0.544	0.18
449_R	466_G	0.543	0.17
64_E	166_R	0.543	0.17
119_G	437_G	0.542	0.17
195_A	294_I	0.541	0.17
420_N	461_D	0.540	0.17
377_L	487_G	0.539	0.17
142_A	145_L	0.538	0.17
55_T	295_D	0.538	0.17
455_P	475_L	0.538	0.17
106_P	155_D	0.536	0.17
240_A	366_A	0.535	0.17
285_R	404_F	0.535	0.17
38_G	42_A	0.534	0.17
236_V	248_L	0.532	0.17
26_A	113_S	0.532	0.17
122_T	131_D	0.532	0.17
96_S	136_P	0.531	0.17
78_L	137_E	0.530	0.17
444_N	452_M	0.530	0.17
81_A	298_P	0.530	0.17
266_Y	456_L	0.529	0.17
25_L	49_V	0.529	0.17
27_A	205_E	0.528	0.17
405_Y	443_G	0.526	0.17
259_P	344_R	0.524	0.17
453_L	461_D	0.524	0.17
261_V	332_L	0.524	0.17
21_R	194_E	0.523	0.17
365_K	413_L	0.522	0.17
51_V	74_P	0.522	0.17
366_A	477_T	0.522	0.17
365_K	439_L	0.521	0.17
418_T	450_P	0.521	0.17
237_L	381_F	0.521	0.17
286_F	379_E	0.520	0.17
51_V	249_V	0.519	0.17
96_S	311_E	0.519	0.17
47_G	121_G	0.519	0.17
425_P	436_T	0.518	0.17
142_A	197_D	0.517	0.17
168_L	235_H	0.517	0.17
375_T	487_G	0.516	0.17
119_G	124_D	0.516	0.17
63_D	143_D	0.515	0.17
67_A	296_E	0.515	0.17
169_V	175_T	0.512	0.16
123_I	229_H	0.511	0.16
265_F	369_N	0.510	0.16
362_S	477_T	0.510	0.16
23_E	27_A	0.509	0.16
413_L	468_A	0.508	0.16
369_N	490_C	0.508	0.16
36_I	47_G	0.507	0.16
369_N	384_E	0.506	0.16
233_K	496_R	0.505	0.16
52_T	58_T	0.505	0.16
373_D	428_E	0.504	0.16
256_M	444_N	0.504	0.16
181_L	440_I	0.504	0.16
35_T	181_L	0.502	0.16
68_Y	77_R	0.501	0.16
47_G	186_V	0.500	0.16

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l4gA	2	0.9641	100	0.378	Contact Map
2odrC	4	0.5159	100	0.679	Contact Map
2du7A	7	0.5876	100	0.686	Contact Map
1b7yA	2	0.498	100	0.688	Contact Map
2odrB	3	0.5159	100	0.69	Contact Map
2odrD	4	0.5159	100	0.69	Contact Map
2odrA	4	0.5159	100	0.691	Contact Map
2du3A	4	0.5976	100	0.696	Contact Map
4p72C	2	0.4701	100	0.72	Contact Map
3pcoA	2	0.6235	100	0.728	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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