GREMLIN Database
SYFB - Phenylalanine--tRNA ligase beta subunit
UniProt: Q9HMK3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 567 (526)
Sequences: 4431 (3145)
Seq/√Len: 137.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
164_T236_E5.7251.00
484_A559_F5.1381.00
186_D194_G4.4151.00
186_D196_T3.9361.00
447_L485_V3.7351.00
102_G238_F3.5751.00
161_L218_S3.3771.00
104_V163_Y3.3221.00
318_L338_V3.1431.00
514_P528_T3.1191.00
105_I239_V3.0941.00
21_D24_E3.0471.00
528_T535_P2.9821.00
192_P226_R2.8421.00
297_E303_E2.8101.00
292_S341_P2.8031.00
525_R541_E2.7921.00
514_P530_E2.7491.00
165_G231_T2.7431.00
530_E535_P2.7211.00
178_D205_D2.7101.00
394_N446_V2.6821.00
13_R124_K2.6431.00
100_V161_L2.6071.00
400_E433_T2.5791.00
207_Y255_I2.5741.00
167_D214_I2.5331.00
141_H160_S2.4981.00
290_H328_D2.4821.00
295_R341_P2.4781.00
106_R236_E2.4571.00
312_L351_A2.3941.00
37_E48_E2.3761.00
440_L558_G2.3581.00
479_R562_E2.3471.00
189_T195_E2.2921.00
117_S121_L2.2921.00
305_T308_A2.2901.00
296_I309_V2.2031.00
389_F499_R2.2011.00
293_H309_V2.1881.00
176_L197_Y2.1691.00
100_V218_S2.1601.00
119_I123_E2.1231.00
291_V344_V2.1191.00
392_L459_L2.1111.00
217_F228_T2.0971.00
112_A122_Q2.0961.00
400_E423_T2.0751.00
311_D315_R2.0701.00
16_G74_R2.0451.00
204_H255_I2.0361.00
534_Q565_A2.0211.00
270_V333_P2.0011.00
188_L194_G1.9971.00
288_T330_E1.9971.00
308_A311_D1.9881.00
288_T328_D1.9831.00
166_I217_F1.9721.00
299_L342_V1.9641.00
329_V344_V1.9481.00
23_D27_Q1.9321.00
99_Y279_L1.8951.00
129_M146_L1.8821.00
300_L349_G1.8811.00
96_D175_P1.8771.00
187_V219_F1.8601.00
291_V296_I1.8431.00
392_L446_V1.8361.00
174_V185_A1.8231.00
541_E555_P1.8111.00
392_L443_L1.7791.00
531_I536_A1.7571.00
523_D543_H1.7551.00
537_G561_F1.7551.00
92_D172_T1.7461.00
168_P213_D1.7441.00
32_L69_H1.7361.00
122_Q133_R1.7221.00
297_E302_V1.7161.00
310_V314_E1.6921.00
26_R39_E1.6911.00
319_D330_E1.6871.00
174_V211_Y1.6791.00
212_D215_G1.6701.00
126_H133_R1.6691.00
496_A539_I1.6651.00
207_Y256_I1.6471.00
331_I338_V1.6421.00
207_Y252_M1.6401.00
385_V460_A1.6371.00
384_L482_V1.6311.00
469_D477_A1.6251.00
530_E533_G1.6001.00
293_H306_T1.5941.00
215_G227_R1.5921.00
25_L66_L1.5921.00
486_L496_A1.5891.00
167_D215_G1.5881.00
295_R345_V1.5841.00
504_C511_L1.5711.00
438_W441_P1.5431.00
516_T528_T1.5421.00
211_Y216_L1.5381.00
500_L504_C1.5321.00
268_E333_P1.5291.00
101_T273_D1.5211.00
163_Y238_F1.5181.00
158_A239_V1.5161.00
28_D70_A1.5101.00
7_D42_D1.5101.00
541_E557_A1.4981.00
459_L485_V1.4971.00
521_F526_A1.4891.00
58_S155_G1.4891.00
380_V563_L1.4861.00
109_D235_R1.4781.00
500_L559_F1.4761.00
522_I544_P1.4481.00
223_I260_L1.4461.00
310_V327_Y1.4431.00
47_L62_I1.4421.00
292_S295_R1.4371.00
289_K338_V1.4341.00
446_V459_L1.4291.00
222_V252_M1.4271.00
64_R334_Y1.4241.00
321_T328_D1.4211.00
481_T560_E1.4201.00
101_T272_V1.4101.00
88_I238_F1.4061.00
91_T172_T1.4011.00
8_P22_D1.4011.00
15_T66_L1.3951.00
22_D43_G1.3891.00
444_A485_V1.3891.00
188_L226_R1.3861.00
226_R229_E1.3801.00
443_L483_A1.3801.00
293_H327_Y1.3801.00
521_F538_V1.3741.00
448_E452_H1.3741.00
93_V175_P1.3731.00
308_A356_D1.3721.00
168_P212_D1.3671.00
295_R298_T1.3661.00
122_Q126_H1.3661.00
71_G311_D1.3641.00
107_G235_R1.3601.00
299_L345_V1.3561.00
304_F309_V1.3561.00
522_I543_H1.3531.00
443_L485_V1.3511.00
462_V563_L1.3491.00
371_T374_S1.3491.00
314_E320_A1.3471.00
107_G236_E1.3431.00
34_I56_R1.3411.00
110_L136_G1.3331.00
370_R378_R1.3311.00
131_R261_D1.3311.00
313_A344_V1.3241.00
318_L329_V1.3151.00
484_A496_A1.3121.00
521_F558_G1.3091.00
208_P220_P1.3071.00
96_D248_T1.3051.00
387_L502_A1.3021.00
172_T213_D1.2981.00
310_V322_P1.2921.00
98_P243_G1.2881.00
31_G355_N1.2811.00
176_L185_A1.2761.00
38_G46_K1.2711.00
389_F486_L1.2691.00
405_D419_A1.2661.00
321_T330_E1.2631.00
320_A327_Y1.2541.00
219_F256_I1.2511.00
22_D26_R1.2491.00
287_R331_I1.2491.00
8_P12_R1.2461.00
288_T331_I1.2441.00
49_F57_L1.2431.00
423_T434_I1.2411.00
175_P206_T1.2401.00
121_L143_L1.2391.00
512_E533_G1.2371.00
383_A502_A1.2321.00
35_E48_E1.2321.00
352_Y356_D1.2311.00
88_I166_I1.2231.00
204_H207_Y1.2231.00
296_I348_L1.2231.00
67_R73_D1.2141.00
451_T554_V1.2021.00
28_D69_H1.2001.00
318_L331_I1.1961.00
465_A481_T1.1931.00
291_V345_V1.1911.00
100_V171_D1.1881.00
90_V102_G1.1851.00
480_R564_D1.1760.99
123_E126_H1.1740.99
26_R45_F1.1710.99
71_G315_R1.1710.99
144_A147_K1.1700.99
110_L137_A1.1680.99
481_T562_E1.1670.99
141_H158_A1.1610.99
389_F484_A1.1580.99
119_I122_Q1.1550.99
171_D218_S1.1540.99
513_T529_I1.1530.99
5_D46_K1.1510.99
500_L529_I1.1420.99
380_V503_L1.1420.99
377_E480_R1.1380.99
178_D184_P1.1370.99
439_A442_S1.1370.99
209_A216_L1.1300.99
308_A352_Y1.1290.99
404_F407_M1.1290.99
141_H239_V1.1270.99
24_E27_Q1.1270.99
165_G233_D1.1220.99
310_V320_A1.1220.99
108_V137_A1.1170.99
462_V482_V1.1130.99
500_L539_I1.1100.99
109_D112_A1.1090.99
294_D298_T1.1040.99
314_E319_D1.0960.99
171_D217_F1.0930.99
309_V348_L1.0910.99
342_V345_V1.0900.99
259_A265_A1.0860.99
163_Y236_E1.0840.99
248_T252_M1.0840.99
34_I47_L1.0820.99
160_S239_V1.0750.99
295_R299_L1.0740.99
341_P345_V1.0740.99
467_H479_R1.0720.99
287_R339_R1.0670.99
529_I537_G1.0650.99
222_V249_I1.0620.99
164_T235_R1.0600.99
545_G549_E1.0600.99
546_V549_E1.0510.99
245_D248_T1.0510.99
54_L336_V1.0490.99
562_E565_A1.0450.99
308_A312_L1.0430.99
444_A542_L1.0420.99
496_A559_F1.0380.99
484_A500_L1.0360.99
408_R545_G1.0320.99
302_V358_T1.0310.99
523_D544_P1.0260.99
191_H195_E1.0240.99
210_I244_T1.0230.99
184_P196_T1.0230.99
525_R557_A1.0220.99
178_D196_T1.0170.98
19_S25_L1.0090.98
312_L352_Y1.0060.98
124_K143_L1.0050.98
349_G354_F1.0050.98
486_L499_R0.9990.98
387_L499_R0.9980.98
311_D314_E0.9960.98
9_D12_R0.9960.98
195_E258_Y0.9950.98
12_R17_H0.9910.98
383_A506_E0.9880.98
144_A236_E0.9870.98
389_F458_D0.9870.98
19_S70_A0.9830.98
100_V244_T0.9790.98
159_R224_N0.9720.98
33_G56_R0.9680.98
405_D410_T0.9670.98
174_V187_V0.9650.98
349_G357_L0.9640.98
406_R549_E0.9630.98
14_L147_K0.9630.98
401_A405_D0.9600.98
7_D59_V0.9590.98
307_E311_D0.9580.98
381_R462_V0.9550.98
294_D325_D0.9550.98
19_S72_D0.9540.98
68_Y351_A0.9530.98
217_F227_R0.9510.98
6_I62_I0.9500.98
12_R18_R0.9500.98
306_T327_Y0.9450.98
494_E497_K0.9450.98
322_P325_D0.9450.98
178_D204_H0.9430.98
96_D245_D0.9430.98
206_T255_I0.9410.97
318_L347_D0.9370.97
243_G246_Q0.9340.97
29_L62_I0.9330.97
230_V237_L0.9330.97
512_E530_E0.9320.97
535_P538_V0.9320.97
286_V319_D0.9310.97
117_S122_Q0.9310.97
397_M435_L0.9280.97
306_T322_P0.9270.97
518_H538_V0.9250.97
32_L351_A0.9240.97
504_C509_V0.9230.97
456_P489_N0.9220.97
290_H326_G0.9210.97
421_P437_T0.9170.97
547_I552_V0.9130.97
207_Y219_F0.9100.97
174_V209_A0.9080.97
93_V96_D0.9070.97
230_V234_S0.9070.97
304_F352_Y0.9050.97
516_T526_A0.9040.97
518_H521_F0.8970.97
9_D42_D0.8960.97
27_Q31_G0.8910.97
501_Q513_T0.8910.97
60_E148_G0.8900.96
485_V558_G0.8880.96
171_D238_F0.8870.96
542_L558_G0.8770.96
542_L547_I0.8770.96
284_F333_P0.8740.96
464_F478_E0.8680.96
209_A219_F0.8610.96
528_T538_V0.8600.96
497_K501_Q0.8600.96
105_I236_E0.8590.96
445_M449_T0.8560.96
563_L566_L0.8550.96
171_D244_T0.8490.95
296_I345_V0.8490.95
295_R342_V0.8480.95
442_S463_G0.8480.95
491_A495_D0.8440.95
34_I48_E0.8420.95
131_R146_L0.8400.95
498_A501_Q0.8390.95
34_I49_F0.8380.95
187_V209_A0.8370.95
444_A550_H0.8370.95
89_D169_D0.8320.95
306_T310_V0.8290.95
36_Y47_L0.8280.95
68_Y316_A0.8270.95
226_R231_T0.8270.95
106_R163_Y0.8270.95
76_V79_P0.8250.95
377_E462_V0.8240.95
187_V216_L0.8210.94
100_V210_I0.8180.94
190_E224_N0.8170.94
195_E229_E0.8160.94
158_A241_L0.8130.94
14_L143_L0.8120.94
59_V129_M0.8120.94
404_F409_L0.8110.94
218_S244_T0.8100.94
104_V238_F0.8090.94
442_S466_A0.8070.94
451_T487_A0.8060.94
338_V344_V0.8030.94
117_S136_G0.7990.94
164_T233_D0.7930.93
71_G308_A0.7900.93
167_D212_D0.7900.93
317_G334_Y0.7870.93
100_V241_L0.7870.93
512_E532_D0.7860.93
401_A406_R0.7840.93
384_L503_L0.7840.93
26_R36_Y0.7830.93
243_G267_I0.7830.93
161_L225_G0.7830.93
64_R426_E0.7820.93
76_V81_T0.7820.93
279_L282_P0.7820.93
379_S382_Q0.7810.93
160_S218_S0.7810.93
37_E49_F0.7790.93
92_D177_D0.7790.93
108_V236_E0.7760.93
165_G227_R0.7750.93
405_D418_A0.7690.92
277_R280_H0.7680.92
547_I555_P0.7680.92
6_I59_V0.7670.92
16_G72_D0.7650.92
88_I102_G0.7620.92
380_V482_V0.7610.92
309_V345_V0.7590.92
56_R65_S0.7580.92
185_A211_Y0.7570.92
373_S564_D0.7550.92
289_K329_V0.7550.92
175_P248_T0.7550.92
545_G548_V0.7520.91
7_D127_A0.7510.91
8_P45_F0.7500.91
310_V323_T0.7480.91
290_H323_T0.7480.91
487_A554_V0.7470.91
372_E376_L0.7450.91
166_I171_D0.7440.91
468_A476_V0.7440.91
219_F222_V0.7430.91
370_R374_S0.7430.91
288_T321_T0.7430.91
400_E434_I0.7430.91
167_D213_D0.7420.91
121_L140_I0.7410.91
421_P434_I0.7410.91
430_Q433_T0.7380.91
138_I224_N0.7370.91
210_I225_G0.7350.91
293_H297_E0.7350.91
482_V559_F0.7330.90
17_H72_D0.7330.90
112_A121_L0.7310.90
436_R463_G0.7300.90
552_V556_V0.7270.90
172_T175_P0.7270.90
137_A140_I0.7260.90
189_T223_I0.7230.90
39_E43_G0.7210.90
297_E306_T0.7200.90
95_A245_D0.7200.90
407_M441_P0.7190.90
447_L487_A0.7190.90
323_T326_G0.7170.89
24_E28_D0.7170.89
404_F421_P0.7160.89
110_L232_T0.7150.89
87_A106_R0.7140.89
232_T235_R0.7110.89
76_V80_D0.7110.89
185_A209_A0.7080.89
486_L491_A0.7070.89
9_D41_E0.7060.89
276_D279_L0.7060.89
381_R391_D0.7050.89
197_Y209_A0.7040.89
464_F480_R0.7030.89
436_R461_E0.7030.89
188_L192_P0.7020.88
105_I237_L0.7000.88
383_A386_G0.7000.88
208_P244_T0.6990.88
166_I238_F0.6970.88
7_D129_M0.6960.88
40_T46_K0.6950.88
286_V333_P0.6920.88
384_L484_A0.6910.88
187_V211_Y0.6910.88
270_V286_V0.6890.88
534_Q562_E0.6880.87
188_L227_R0.6870.87
253_C259_A0.6870.87
286_V330_E0.6860.87
36_Y45_F0.6830.87
138_I159_R0.6830.87
161_L228_T0.6830.87
28_D31_G0.6830.87
442_S446_V0.6820.87
148_G275_P0.6820.87
398_T442_S0.6810.87
400_E405_D0.6810.87
159_R190_E0.6810.87
398_T432_F0.6800.87
174_V177_D0.6800.87
291_V327_Y0.6800.87
449_T453_H0.6790.87
51_A57_L0.6780.87
291_V309_V0.6780.87
468_A475_G0.6780.87
252_M256_I0.6730.86
223_I258_Y0.6710.86
35_E47_L0.6680.86
304_F312_L0.6650.86
468_A477_A0.6640.86
493_Y527_A0.6630.85
457_Q487_A0.6620.85
525_R555_P0.6620.85
156_T275_P0.6610.85
42_D127_A0.6600.85
60_E75_G0.6600.85
61_G64_R0.6600.85
137_A237_L0.6600.85
407_M520_S0.6600.85
220_P241_L0.6590.85
405_D409_L0.6590.85
259_A264_G0.6590.85
148_G274_Y0.6590.85
10_E124_K0.6580.85
8_P43_G0.6580.85
516_T530_E0.6570.85
482_V500_L0.6570.85
165_G228_T0.6560.85
307_E322_P0.6560.85
172_T211_Y0.6550.85
516_T535_P0.6540.85
447_L556_V0.6530.85
88_I169_D0.6510.84
292_S326_G0.6510.84
291_V313_A0.6510.84
144_A275_P0.6500.84
52_D55_D0.6460.84
392_L485_V0.6460.84
422_A476_V0.6440.84
81_T84_P0.6430.84
196_T205_D0.6420.84
316_A351_A0.6410.83
511_L536_A0.6390.83
553_E556_V0.6390.83
420_Q468_A0.6380.83
187_V225_G0.6380.83
382_Q385_V0.6370.83
423_T433_T0.6370.83
88_I163_Y0.6370.83
391_D460_A0.6360.83
323_T328_D0.6360.83
65_S347_D0.6330.83
48_E54_L0.6330.83
243_G272_V0.6320.83
292_S345_V0.6300.82
513_T539_I0.6300.82
109_D232_T0.6300.82
34_I62_I0.6280.82
14_L60_E0.6280.82
467_H477_A0.6270.82
456_P487_A0.6270.82
536_A565_A0.6270.82
117_S133_R0.6260.82
220_P249_I0.6260.82
249_I252_M0.6260.82
451_T553_E0.6230.82
90_V238_F0.6220.82
300_L357_L0.6200.81
312_L316_A0.6190.81
276_D280_H0.6190.81
444_A556_V0.6190.81
484_A499_R0.6180.81
375_R379_S0.6180.81
447_L457_Q0.6180.81
511_L537_G0.6170.81
522_I527_A0.6170.81
395_F432_F0.6160.81
541_E547_I0.6140.81
96_D208_P0.6140.81
75_G80_D0.6130.81
49_F56_R0.6130.81
22_D45_F0.6120.81
166_I169_D0.6120.81
424_I435_L0.6120.81
426_E432_F0.6120.81
62_I65_S0.6110.80
177_D186_D0.6110.80
306_T325_D0.6110.80
268_E271_T0.6110.80
293_H296_I0.6110.80
56_R62_I0.6110.80
331_I339_R0.6100.80
462_V480_R0.6100.80
220_P242_T0.6090.80
29_L34_I0.6080.80
164_T231_T0.6080.80
292_S342_V0.6080.80
469_D475_G0.6080.80
494_E501_Q0.6070.80
377_E381_R0.6070.80
169_D213_D0.6070.80
380_V507_F0.6060.80
234_S237_L0.6050.80
78_I81_T0.6050.80
244_T263_R0.6030.80
23_D39_E0.6000.79
435_L466_A0.6000.79
110_L121_L0.5980.79
112_A136_G0.5980.79
14_L59_V0.5960.79
299_L341_P0.5950.79
110_L135_K0.5950.79
407_M550_H0.5940.79
398_T441_P0.5940.79
100_V173_F0.5900.78
493_Y496_A0.5890.78
224_N242_T0.5880.78
102_G171_D0.5880.78
189_T229_E0.5880.78
521_F540_G0.5860.78
502_A506_E0.5860.78
529_I561_F0.5850.78
220_P240_E0.5850.78
33_G50_E0.5850.78
169_D185_A0.5850.78
379_S383_A0.5840.77
482_V503_L0.5840.77
87_A104_V0.5840.77
219_F248_T0.5840.77
374_S378_R0.5830.77
86_W104_V0.5830.77
518_H528_T0.5820.77
243_G269_D0.5820.77
195_E256_I0.5820.77
176_L209_A0.5820.77
30_F35_E0.5820.77
29_L47_L0.5820.77
526_A538_V0.5810.77
379_S506_E0.5800.77
511_L531_I0.5790.77
212_D217_F0.5790.77
34_I65_S0.5790.77
26_R30_F0.5790.77
79_P83_A0.5790.77
285_A288_T0.5790.77
134_A138_I0.5780.77
18_R24_E0.5760.76
141_H224_N0.5740.76
487_A556_V0.5720.76
18_R72_D0.5720.76
137_A160_S0.5720.76
394_N442_S0.5720.76
529_I539_I0.5700.76
406_R409_L0.5680.75
517_T526_A0.5680.75
396_N466_A0.5670.75
527_A544_P0.5660.75
214_I227_R0.5650.75
401_A549_E0.5640.75
302_V357_L0.5640.75
59_V62_I0.5620.75
177_D205_D0.5600.74
424_I432_F0.5580.74
241_L272_V0.5580.74
300_L345_V0.5580.74
265_A268_E0.5580.74
409_L419_A0.5580.74
492_S495_D0.5580.74
440_L521_F0.5570.74
173_F218_S0.5570.74
432_F445_M0.5540.74
125_L131_R0.5530.74
25_L45_F0.5530.74
97_R134_A0.5520.73
17_H66_L0.5520.73
148_G271_T0.5520.73
524_G543_H0.5510.73
15_T67_R0.5510.73
262_A265_A0.5510.73
100_V158_A0.5490.73
541_E554_V0.5490.73
121_L144_A0.5480.73
23_D26_R0.5480.73
11_L35_E0.5480.73
429_S433_T0.5470.73
66_L70_A0.5470.73
160_S230_V0.5470.73
67_R71_G0.5460.73
399_S431_D0.5450.72
389_F496_A0.5450.72
397_M428_Y0.5440.72
409_L546_V0.5440.72
444_A552_V0.5440.72
65_S68_Y0.5440.72
511_L529_I0.5440.72
486_L495_D0.5430.72
142_D145_M0.5420.72
492_S557_A0.5420.72
33_G49_F0.5410.72
141_H159_R0.5410.72
49_F54_L0.5410.72
136_G140_I0.5400.72
486_L557_A0.5400.72
37_E254_A0.5400.72
297_E304_F0.5390.72
48_E51_A0.5390.72
500_L561_F0.5380.72
112_A117_S0.5380.72
185_A197_Y0.5370.71
52_D57_L0.5360.71
404_F437_T0.5360.71
135_K232_T0.5360.71
56_R397_M0.5360.71
5_D40_T0.5360.71
67_R72_D0.5360.71
407_M444_A0.5350.71
218_S249_I0.5340.71
5_D129_M0.5340.71
105_I108_V0.5340.71
163_Y169_D0.5330.71
86_W163_Y0.5330.71
522_I541_E0.5330.71
294_D324_D0.5320.71
189_T193_T0.5310.71
253_C258_Y0.5310.71
447_L552_V0.5300.70
133_R136_G0.5300.70
313_A348_L0.5300.70
79_P82_N0.5300.70
405_D408_R0.5290.70
71_G314_E0.5290.70
175_P208_P0.5290.70
75_G81_T0.5280.70
396_N435_L0.5270.70
78_I84_P0.5270.70
406_R410_T0.5270.70
195_E219_F0.5260.70
88_I100_V0.5260.70
33_G57_L0.5260.70
32_L66_L0.5250.70
58_S145_M0.5240.70
271_T274_Y0.5230.69
518_H535_P0.5230.69
497_K513_T0.5230.69
223_I229_E0.5230.69
17_H25_L0.5210.69
60_E76_V0.5210.69
470_G475_G0.5210.69
427_P488_R0.5200.69
383_A503_L0.5200.69
132_K223_I0.5200.69
319_D331_I0.5190.69
376_L379_S0.5190.69
134_A137_A0.5190.69
97_R242_T0.5190.69
224_N240_E0.5180.69
547_I556_V0.5180.69
99_Y281_R0.5170.69
97_R173_F0.5170.69
159_R223_I0.5170.69
161_L244_T0.5170.69
145_M156_T0.5170.69
22_D39_E0.5170.69
292_S296_I0.5170.69
521_F539_I0.5160.68
83_A326_G0.5150.68
241_L275_P0.5140.68
90_V100_V0.5130.68
494_E498_A0.5130.68
184_P197_Y0.5130.68
80_D83_A0.5120.68
46_K49_F0.5120.68
57_L495_D0.5120.68
29_L36_Y0.5120.68
74_R78_I0.5120.68
34_I51_A0.5120.68
357_L360_R0.5120.68
305_T311_D0.5110.68
6_I129_M0.5110.68
404_F408_R0.5100.68
312_L315_R0.5090.67
11_L63_A0.5090.67
161_L171_D0.5090.67
522_I525_R0.5080.67
190_E240_E0.5080.67
161_L173_F0.5080.67
86_W106_R0.5070.67
174_V216_L0.5070.67
100_V160_S0.5070.67
141_H225_G0.5070.67
192_P229_E0.5070.67
38_G48_E0.5070.67
25_L29_L0.5060.67
509_V531_I0.5050.67
86_W95_A0.5050.67
50_E265_A0.5050.67
105_I140_I0.5040.67
253_C260_L0.5030.66
195_E261_D0.5030.66
206_T256_I0.5030.66
33_G51_A0.5030.66
270_V284_F0.5030.66
99_Y273_D0.5020.66
13_R143_L0.5020.66
515_P530_E0.5000.66
19_S24_E0.5000.66
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2rhqB 2 0.9365 100 0.158 Contact Map
4p72A 2 0.9312 100 0.164 Contact Map
3pcoB 2 0.9383 100 0.167 Contact Map
1b7yB 2 0.9189 100 0.175 Contact Map
3l4gB 2 0.97 100 0.242 Contact Map
2cxiA 3 0.5714 100 0.564 Contact Map
2rhqA 2 0.3827 100 0.707 Contact Map
3icaA 2 0.3369 100 0.737 Contact Map
3ig2A 4 0.3333 100 0.738 Contact Map
4p72C 2 0.3651 100 0.761 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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