Q9HMF7 - HALSA - GREMLIN Contacts

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Q9HMF7 - TRK potassium uptake system protein

UniProt:	Q9HMF7	Sequences: MHVAVDTVGRDVGRILQAVSLLLAASVAVVAVNGEFFAIPAFVVSAAVMGGIGTGLARLCRGARPPKKPDAMVTAATAWAVVGVLGALPFVLVAWTMRLHLLPGLTPPLNATTRVFLHPLNAVFETISGFTGTGLTMATTEGDLPRALHWWRSLTEWVGGVGVIVLTVAILRRGDGSSGSYTLYESEARSEKIHPSIITTVQEIWRLFVGLTLGAIALLLLAGMPPWDAINHGMTGIATGGFAVRAGSIGAYNSPAIEYATVPIMIAGSIAFPVHYLLFTGDLRNVYADLQTRWVVAWFAVGAAVLSALLFYTGQYDSLAASFRIGLFQFVSATSNTGFGTTTIGRGTERVWQTGPTLFACLGMLTGAAAGSTVSGIKLIRVITLIKGTAWQIRDVFRPASAIRSLRIGDRKLSEHQAQREYAEATLVFVLWLAFLAIGVAVLLAALSPQHPLEYVLFDVMSAQSNVGLDAGITSPGMPALAKGMLIINMWVGRLEIIPIAVLISAVLRHGDFYR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	515 (405)
Sequences:	5222 (3913)
Seq/√Len:	194.4

ECOLI - TRKH TRKG
BACSU - KTRB KTRD
HALSA - Q9HMF7 Q9HQ81 Q9HPA9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
368_A	374_V	4.162	1.00
439_G	489_N	3.655	1.00
121_N	483_K	3.456	1.00
216_I	230_I	3.324	1.00
262_V	327_L	3.236	1.00
120_L	484_G	3.098	1.00
219_L	261_T	3.085	1.00
215_A	264_I	2.888	1.00
157_W	212_T	2.792	1.00
222_A	254_S	2.539	1.00
369_A	379_L	2.462	1.00
343_T	351_V	2.446	1.00
245_R	251_A	2.391	1.00
247_G	251_A	2.371	1.00
218_L	260_A	2.364	1.00
87_A	119_P	2.348	1.00
452_P	455_Y	2.332	1.00
156_E	235_T	2.302	1.00
222_A	256_A	2.297	1.00
318_S	321_A	2.273	1.00
123_V	487_I	2.247	1.00
153_S	231_N	2.247	1.00
447_L	482_A	2.207	1.00
266_I	299_F	2.193	1.00
294_W	383_I	2.166	1.00
305_V	359_F	2.126	1.00
220_L	226_P	2.124	1.00
149_H	227_W	2.101	1.00
146_R	150_W	2.091	1.00
303_A	327_L	2.090	1.00
91_V	119_P	2.083	1.00
235_T	339_F	2.013	1.00
120_L	487_I	2.011	1.00
333_A	360_A	2.011	1.00
127_I	487_I	1.994	1.00
222_A	260_A	1.984	1.00
306_L	356_P	1.980	1.00
232_H	243_A	1.972	1.00
117_L	143_D	1.946	1.00
216_I	226_P	1.941	1.00
258_E	325_I	1.937	1.00
302_G	363_G	1.912	1.00
87_A	91_V	1.904	1.00
258_E	324_R	1.880	1.00
269_S	295_V	1.875	1.00
262_V	331_V	1.864	1.00
222_A	257_I	1.854	1.00
269_S	335_S	1.845	1.00
147_A	151_W	1.807	1.00
120_L	480_A	1.799	1.00
83_G	127_I	1.787	1.00
139_T	142_G	1.777	1.00
307_S	311_F	1.762	1.00
256_A	260_A	1.760	1.00
249_I	261_T	1.758	1.00
220_L	229_A	1.752	1.00
184_Y	187_E	1.731	1.00
266_I	331_V	1.720	1.00
118_H	121_N	1.716	1.00
237_I	268_G	1.703	1.00
302_G	330_F	1.700	1.00
361_C	461_M	1.686	1.00
218_L	256_A	1.678	1.00
320_A	324_R	1.678	1.00
459_D	474_T	1.670	1.00
440_V	457_L	1.662	1.00
136_T	140_T	1.656	1.00
255_P	324_R	1.631	1.00
258_E	341_T	1.616	1.00
259_Y	263_P	1.603	1.00
462_S	467_V	1.580	1.00
253_N	325_I	1.579	1.00
436_L	461_M	1.572	1.00
183_L	187_E	1.571	1.00
140_T	143_D	1.563	1.00
76_A	491_W	1.548	1.00
307_S	326_G	1.544	1.00
447_L	479_P	1.542	1.00
259_Y	324_R	1.540	1.00
202_Q	206_R	1.534	1.00
297_A	301_V	1.512	1.00
384_T	413_L	1.510	1.00
385_L	429_F	1.510	1.00
265_M	337_T	1.495	1.00
390_A	394_R	1.492	1.00
216_I	233_G	1.489	1.00
336_N	467_V	1.488	1.00
377_I	382_V	1.488	1.00
117_L	144_L	1.464	1.00
309_L	356_P	1.462	1.00
455_Y	471_A	1.453	1.00
236_G	261_T	1.438	1.00
90_F	155_T	1.434	1.00
128_S	242_F	1.431	1.00
265_M	332_S	1.429	1.00
245_R	252_Y	1.425	1.00
299_F	331_V	1.420	1.00
259_Y	320_A	1.414	1.00
219_L	257_I	1.413	1.00
292_T	296_V	1.410	1.00
330_F	333_A	1.409	1.00
447_L	481_L	1.396	1.00
439_G	485_M	1.391	1.00
444_L	447_L	1.391	1.00
125_E	137_M	1.387	1.00
289_D	409_G	1.387	1.00
451_H	473_I	1.385	1.00
120_L	483_K	1.381	1.00
313_T	316_Y	1.377	1.00
141_E	246_A	1.374	1.00
149_H	153_S	1.371	1.00
228_D	245_R	1.371	1.00
218_L	222_A	1.369	1.00
314_G	317_D	1.364	1.00
366_T	379_L	1.362	1.00
231_N	244_V	1.359	1.00
470_D	474_T	1.359	1.00
301_V	305_V	1.355	1.00
284_R	288_A	1.354	1.00
156_E	240_G	1.352	1.00
263_P	267_A	1.351	1.00
119_P	123_V	1.345	1.00
484_G	488_I	1.345	1.00
436_L	464_Q	1.344	1.00
127_I	491_W	1.342	1.00
224_M	257_I	1.338	1.00
311_F	322_S	1.333	1.00
259_Y	327_L	1.325	1.00
484_G	487_I	1.324	1.00
329_Q	341_T	1.312	1.00
224_M	228_D	1.312	1.00
344_I	360_A	1.299	1.00
306_L	360_A	1.292	1.00
123_V	484_G	1.288	1.00
294_W	379_L	1.286	1.00
362_L	366_T	1.280	1.00
361_C	457_L	1.276	1.00
443_L	485_M	1.271	1.00
117_L	138_A	1.269	1.00
303_A	326_G	1.266	1.00
405_S	412_K	1.262	1.00
259_Y	323_F	1.258	1.00
236_G	339_F	1.252	1.00
319_L	323_F	1.247	1.00
198_I	202_Q	1.246	1.00
226_P	230_I	1.246	1.00
277_L	285_N	1.245	1.00
215_A	233_G	1.241	1.00
220_L	225_P	1.237	1.00
451_H	456_V	1.237	1.00
232_H	244_V	1.229	1.00
357_T	471_A	1.227	1.00
300_A	303_A	1.227	1.00
146_R	227_W	1.221	1.00
129_G	242_F	1.220	1.00
140_T	246_A	1.216	1.00
298_W	379_L	1.215	1.00
488_I	492_V	1.213	1.00
432_W	464_Q	1.207	1.00
366_T	382_V	1.207	1.00
473_I	477_G	1.205	1.00
126_T	155_T	1.201	1.00
307_S	322_S	1.198	1.00
255_P	258_E	1.195	1.00
313_T	317_D	1.189	1.00
247_G	250_G	1.188	1.00
121_N	137_M	1.183	1.00
211_L	267_A	1.178	1.00
439_G	460_V	1.177	1.00
344_I	352_W	1.174	1.00
139_T	246_A	1.168	1.00
236_G	264_I	1.167	1.00
440_V	460_V	1.164	1.00
144_L	152_R	1.158	1.00
266_I	296_V	1.156	1.00
325_I	329_Q	1.146	1.00
115_V	145_P	1.138	1.00
250_G	340_G	1.138	1.00
478_M	486_L	1.134	1.00
384_T	418_A	1.126	1.00
460_V	489_N	1.126	1.00
153_S	230_I	1.125	1.00
325_I	342_T	1.121	1.00
258_E	262_V	1.113	1.00
123_V	127_I	1.112	1.00
303_A	323_F	1.111	1.00
303_A	330_F	1.105	1.00
118_H	480_A	1.104	1.00
444_L	482_A	1.103	1.00
298_W	302_G	1.099	1.00
184_Y	188_A	1.098	1.00
321_A	325_I	1.094	1.00
211_L	275_H	1.086	1.00
183_L	186_S	1.086	1.00
361_C	458_F	1.081	1.00
443_L	481_L	1.080	1.00
94_A	147_A	1.079	1.00
86_G	155_T	1.076	1.00
365_L	436_L	1.075	1.00
153_S	227_W	1.073	1.00
305_V	355_G	1.072	1.00
150_W	154_L	1.065	1.00
86_G	126_T	1.064	1.00
344_I	471_A	1.061	1.00
370_A	380_I	1.056	1.00
250_G	343_T	1.053	1.00
436_L	440_V	1.052	1.00
262_V	303_A	1.042	1.00
353_Q	356_P	1.034	1.00
265_M	331_V	1.032	1.00
259_Y	262_V	1.029	1.00
217_A	221_L	1.028	1.00
293_R	409_G	1.028	1.00
303_A	307_S	1.027	1.00
91_V	122_A	1.025	1.00
80_A	491_W	1.022	1.00
180_S	187_E	1.018	1.00
253_N	258_E	1.018	1.00
215_A	261_T	1.017	1.00
255_P	259_Y	1.017	1.00
290_L	383_I	1.012	1.00
206_R	210_G	1.009	1.00
309_L	355_G	1.007	1.00
478_M	482_A	1.005	1.00
153_S	234_M	1.004	1.00
306_L	330_F	0.999	1.00
93_V	148_L	0.994	1.00
266_I	295_V	0.989	1.00
78_A	163_V	0.987	0.99
479_P	482_A	0.985	0.99
294_W	386_I	0.982	0.99
415_E	419_Q	0.980	0.99
140_T	144_L	0.980	0.99
146_R	149_H	0.980	0.99
82_V	130_F	0.979	0.99
243_A	246_A	0.976	0.99
225_P	229_A	0.973	0.99
290_L	387_K	0.972	0.99
254_S	257_I	0.972	0.99
325_I	341_T	0.971	0.99
73_V	77_T	0.970	0.99
357_T	455_Y	0.970	0.99
212_T	233_G	0.969	0.99
215_A	260_A	0.966	0.99
138_A	144_L	0.966	0.99
255_P	320_A	0.965	0.99
161_V	205_W	0.962	0.99
428_V	432_W	0.961	0.99
290_L	409_G	0.960	0.99
219_L	236_G	0.958	0.99
243_A	248_S	0.958	0.99
298_W	366_T	0.956	0.99
215_A	219_L	0.952	0.99
460_V	486_L	0.949	0.99
150_W	227_W	0.946	0.99
129_G	152_R	0.946	0.99
274_V	292_T	0.943	0.99
87_A	123_V	0.943	0.99
463_A	486_L	0.942	0.99
137_M	140_T	0.939	0.99
221_L	256_A	0.936	0.99
302_G	359_F	0.934	0.99
355_G	441_A	0.929	0.99
215_A	236_G	0.927	0.99
443_L	447_L	0.915	0.99
307_S	323_F	0.915	0.99
345_G	351_V	0.914	0.99
345_G	357_T	0.914	0.99
83_G	130_F	0.914	0.99
125_E	140_T	0.910	0.99
142_G	246_A	0.906	0.99
388_G	426_T	0.903	0.99
386_I	390_A	0.902	0.99
180_S	184_Y	0.898	0.99
364_M	467_V	0.897	0.99
140_T	152_R	0.892	0.99
219_L	260_A	0.892	0.99
296_V	300_A	0.890	0.99
270_I	292_T	0.889	0.99
267_A	275_H	0.882	0.99
462_S	470_D	0.876	0.99
481_L	485_M	0.874	0.99
299_F	327_L	0.870	0.99
240_G	336_N	0.869	0.99
459_D	470_D	0.867	0.99
244_V	252_Y	0.867	0.99
232_H	245_R	0.866	0.99
179_G	184_Y	0.863	0.99
354_T	454_E	0.863	0.99
77_T	81_V	0.862	0.99
333_A	469_L	0.854	0.99
311_F	319_L	0.852	0.99
182_T	196_S	0.852	0.99
429_F	433_L	0.847	0.98
127_I	500_I	0.846	0.98
125_E	152_R	0.846	0.98
90_F	148_L	0.846	0.98
435_F	492_V	0.844	0.98
84_V	119_P	0.840	0.98
392_Q	419_Q	0.836	0.98
290_L	294_W	0.836	0.98
213_L	217_A	0.835	0.98
370_A	379_L	0.834	0.98
153_S	235_T	0.833	0.98
387_K	408_I	0.830	0.98
217_A	220_L	0.826	0.98
440_V	453_L	0.826	0.98
207_L	211_L	0.822	0.98
329_Q	360_A	0.821	0.98
394_R	404_R	0.821	0.98
219_L	249_I	0.821	0.98
464_Q	489_N	0.820	0.98
249_I	257_I	0.820	0.98
225_P	228_D	0.816	0.98
135_L	462_S	0.814	0.98
211_L	237_I	0.810	0.98
345_G	471_A	0.809	0.98
320_A	323_F	0.809	0.98
482_A	486_L	0.808	0.98
156_E	238_A	0.807	0.98
391_W	406_L	0.805	0.98
387_K	406_L	0.804	0.98
330_F	363_G	0.799	0.98
262_V	266_I	0.798	0.98
203_E	276_Y	0.798	0.98
275_H	286_V	0.794	0.98
88_L	92_L	0.793	0.98
225_P	252_Y	0.791	0.98
180_S	183_L	0.791	0.98
461_M	465_S	0.787	0.97
153_S	156_E	0.783	0.97
216_I	220_L	0.783	0.97
130_F	155_T	0.782	0.97
364_M	462_S	0.779	0.97
83_G	123_V	0.777	0.97
239_T	335_S	0.777	0.97
432_W	436_L	0.774	0.97
299_F	303_A	0.774	0.97
182_T	185_E	0.773	0.97
196_S	199_T	0.772	0.97
119_P	484_G	0.771	0.97
310_L	326_G	0.771	0.97
359_F	441_A	0.769	0.97
277_L	288_A	0.766	0.97
91_V	116_F	0.765	0.97
183_L	188_A	0.761	0.97
166_L	205_W	0.760	0.97
329_Q	344_I	0.757	0.97
125_E	136_T	0.755	0.97
305_V	309_L	0.754	0.97
385_L	389_T	0.751	0.97
185_E	188_A	0.747	0.97
352_W	356_P	0.744	0.96
288_A	292_T	0.740	0.96
136_T	152_R	0.737	0.96
120_L	486_L	0.736	0.96
178_S	198_I	0.736	0.96
178_S	182_T	0.736	0.96
361_C	454_E	0.735	0.96
199_T	202_Q	0.734	0.96
431_L	498_I	0.733	0.96
228_D	232_H	0.732	0.96
231_N	235_T	0.723	0.96
497_I	501_A	0.723	0.96
249_I	252_Y	0.717	0.96
365_L	432_W	0.714	0.96
440_V	461_M	0.714	0.96
210_G	214_G	0.711	0.95
76_A	500_I	0.711	0.95
440_V	456_V	0.710	0.95
156_E	234_M	0.709	0.95
458_F	469_L	0.708	0.95
477_G	480_A	0.704	0.95
342_T	352_W	0.704	0.95
269_S	368_A	0.701	0.95
145_P	148_L	0.699	0.95
292_T	295_V	0.698	0.95
474_T	478_M	0.694	0.95
84_V	87_A	0.694	0.95
327_L	331_V	0.693	0.95
135_L	463_A	0.687	0.95
435_F	489_N	0.687	0.95
208_F	238_A	0.686	0.95
239_T	373_T	0.686	0.95
232_H	261_T	0.684	0.94
391_W	415_E	0.681	0.94
340_G	343_T	0.680	0.94
435_F	439_G	0.679	0.94
89_P	151_W	0.679	0.94
215_A	218_L	0.677	0.94
92_L	147_A	0.677	0.94
273_P	371_G	0.676	0.94
319_L	322_S	0.675	0.94
142_G	245_R	0.674	0.94
389_T	431_L	0.673	0.94
274_V	289_D	0.673	0.94
434_A	438_I	0.671	0.94
358_L	453_L	0.667	0.94
223_G	227_W	0.667	0.94
239_T	337_T	0.666	0.94
122_A	126_T	0.665	0.94
69_P	73_V	0.665	0.94
293_R	297_A	0.664	0.94
291_Q	369_A	0.664	0.94
329_Q	332_S	0.663	0.93
389_T	427_L	0.662	0.93
239_T	268_G	0.661	0.93
249_I	258_E	0.659	0.93
200_T	372_S	0.658	0.93
492_V	500_I	0.657	0.93
456_V	473_I	0.656	0.93
212_T	216_I	0.655	0.93
430_V	434_A	0.653	0.93
71_A	74_T	0.652	0.93
258_E	329_Q	0.652	0.93
282_D	285_N	0.651	0.93
232_H	339_F	0.650	0.93
207_L	275_H	0.650	0.93
385_L	426_T	0.648	0.93
226_P	229_A	0.647	0.93
454_E	471_A	0.646	0.93
91_V	118_H	0.645	0.93
275_H	279_F	0.645	0.93
270_I	275_H	0.645	0.93
340_G	469_L	0.644	0.92
333_A	363_G	0.643	0.92
180_S	186_S	0.643	0.92
156_E	339_F	0.642	0.92
483_K	487_I	0.642	0.92
233_G	264_I	0.641	0.92
315_Q	351_V	0.641	0.92
248_S	467_V	0.640	0.92
205_W	209_V	0.639	0.92
458_F	470_D	0.639	0.92
135_L	469_L	0.639	0.92
117_L	145_P	0.636	0.92
333_A	344_I	0.634	0.92
453_L	456_V	0.633	0.92
256_A	259_Y	0.633	0.92
84_V	123_V	0.633	0.92
444_L	486_L	0.632	0.92
387_K	390_A	0.629	0.92
177_S	180_S	0.626	0.91
72_M	502_V	0.624	0.91
141_E	149_H	0.622	0.91
250_G	253_N	0.620	0.91
457_L	461_M	0.618	0.91
328_F	339_F	0.616	0.91
157_W	208_F	0.615	0.91
271_A	291_Q	0.614	0.91
358_L	362_L	0.612	0.90
227_W	231_N	0.611	0.90
135_L	470_D	0.611	0.90
287_Y	291_Q	0.611	0.90
136_T	141_E	0.610	0.90
455_Y	473_I	0.609	0.90
91_V	117_L	0.609	0.90
124_F	137_M	0.609	0.90
462_S	474_T	0.609	0.90
222_A	252_Y	0.608	0.90
295_V	299_F	0.608	0.90
451_H	478_M	0.608	0.90
210_G	213_L	0.608	0.90
432_W	465_S	0.603	0.90
211_L	268_G	0.602	0.90
464_Q	497_I	0.602	0.90
480_A	483_K	0.601	0.90
332_S	469_L	0.600	0.90
361_C	471_A	0.599	0.89
444_L	460_V	0.599	0.89
344_I	476_P	0.598	0.89
212_T	234_M	0.598	0.89
354_T	357_T	0.597	0.89
458_F	462_S	0.596	0.89
208_F	212_T	0.595	0.89
294_W	298_W	0.595	0.89
213_L	216_I	0.592	0.89
132_G	336_N	0.592	0.89
270_I	295_V	0.592	0.89
368_A	379_L	0.591	0.89
118_H	122_A	0.591	0.89
249_I	328_F	0.590	0.89
284_R	287_Y	0.590	0.89
377_I	429_F	0.590	0.89
221_L	229_A	0.589	0.89
228_D	244_V	0.585	0.88
69_P	77_T	0.585	0.88
250_G	341_T	0.584	0.88
181_Y	186_S	0.584	0.88
138_A	143_D	0.584	0.88
179_G	187_E	0.582	0.88
480_A	484_G	0.582	0.88
246_A	251_A	0.582	0.88
234_M	238_A	0.581	0.88
317_D	326_G	0.580	0.88
83_G	491_W	0.579	0.88
345_G	473_I	0.577	0.88
361_C	365_L	0.573	0.87
91_V	145_P	0.573	0.87
300_A	304_A	0.573	0.87
316_Y	325_I	0.572	0.87
135_L	459_D	0.572	0.87
456_V	460_V	0.571	0.87
435_F	464_Q	0.570	0.87
336_N	375_S	0.569	0.87
132_G	239_T	0.568	0.87
323_F	327_L	0.566	0.87
143_D	146_R	0.566	0.87
88_L	91_V	0.566	0.87
137_M	483_K	0.566	0.87
459_D	469_L	0.566	0.87
455_Y	478_M	0.565	0.87
332_S	337_T	0.564	0.87
135_L	474_T	0.563	0.86
194_H	200_T	0.563	0.86
212_T	237_I	0.563	0.86
384_T	388_G	0.562	0.86
117_L	121_N	0.561	0.86
204_I	494_R	0.561	0.86
364_M	465_S	0.560	0.86
389_T	430_V	0.559	0.86
362_L	437_A	0.559	0.86
67_K	70_D	0.558	0.86
131_T	375_S	0.555	0.86
164_I	478_M	0.554	0.86
385_L	430_V	0.554	0.86
315_Q	342_T	0.554	0.86
459_D	462_S	0.554	0.86
266_I	292_T	0.553	0.85
459_D	486_L	0.552	0.85
219_L	339_F	0.550	0.85
306_L	326_G	0.548	0.85
307_S	319_L	0.548	0.85
431_L	435_F	0.548	0.85
286_V	289_D	0.547	0.85
150_W	153_S	0.547	0.85
94_A	116_F	0.546	0.85
304_A	308_A	0.545	0.85
283_L	287_Y	0.545	0.85
281_G	284_R	0.544	0.85
171_L	503_L	0.543	0.84
436_L	457_L	0.542	0.84
266_I	327_L	0.542	0.84
128_S	133_T	0.542	0.84
278_L	286_V	0.542	0.84
506_A	510_H	0.541	0.84
136_T	235_T	0.541	0.84
451_H	455_Y	0.540	0.84
329_Q	352_W	0.539	0.84
161_V	204_I	0.539	0.84
131_T	238_A	0.537	0.84
138_A	141_E	0.537	0.84
249_I	341_T	0.536	0.84
336_N	464_Q	0.535	0.84
418_A	421_E	0.534	0.83
276_Y	280_T	0.533	0.83
138_A	152_R	0.533	0.83
230_I	233_G	0.533	0.83
248_S	341_T	0.532	0.83
309_L	353_Q	0.531	0.83
243_A	247_G	0.531	0.83
182_T	198_I	0.530	0.83
90_F	126_T	0.530	0.83
393_I	505_S	0.529	0.83
373_T	378_K	0.529	0.83
299_F	330_F	0.528	0.83
73_V	76_A	0.526	0.82
298_W	363_G	0.526	0.82
308_A	312_Y	0.525	0.82
147_A	150_W	0.524	0.82
427_L	431_L	0.522	0.82
470_D	476_P	0.522	0.82
444_L	463_A	0.521	0.82
316_Y	342_T	0.520	0.82
330_F	360_A	0.520	0.82
459_D	463_A	0.520	0.82
235_T	467_V	0.519	0.82
116_F	137_M	0.516	0.81
436_L	460_V	0.516	0.81
331_V	462_S	0.516	0.81
216_I	234_M	0.516	0.81
300_A	319_L	0.515	0.81
157_W	234_M	0.515	0.81
150_W	231_N	0.515	0.81
136_T	340_G	0.514	0.81
265_M	299_F	0.514	0.81
290_L	408_I	0.513	0.81
131_T	371_G	0.512	0.81
265_M	330_F	0.510	0.81
477_G	481_L	0.509	0.80
221_L	226_P	0.509	0.80
136_T	246_A	0.509	0.80
287_Y	292_T	0.509	0.80
143_D	246_A	0.508	0.80
174_G	179_G	0.508	0.80
396_V	407_R	0.507	0.80
122_A	144_L	0.507	0.80
340_G	476_P	0.505	0.80
182_T	188_A	0.505	0.80
86_G	269_S	0.504	0.80
232_H	249_I	0.504	0.80
210_G	263_P	0.503	0.80
307_S	310_L	0.502	0.80
261_T	339_F	0.502	0.80
473_I	476_P	0.501	0.79
437_A	441_A	0.501	0.79
358_L	440_V	0.501	0.79
163_V	192_K	0.500	0.79

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3pjzA	2	0.8951	100	0.154	Contact Map
4j7cI	2	0.7825	100	0.337	Contact Map
3ukmA	2	0.4466	96.5	0.944	Contact Map
4twkA	2	0.4641	93.6	0.954	Contact Map
4wfeA	2	0.3942	91	0.957	Contact Map
4bw5A	2	0.468	90.5	0.958	Contact Map
2ih3C	4	0.1728	87.8	0.96	Contact Map
3vouA	4	0.2602	87.3	0.96	Contact Map
4h33A	3	0.167	86.2	0.961	Contact Map
3effK	4	0.2272	85.3	0.961	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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