GREMLIN Database
Q9HMF0 - Pab N-terminal acetyltransferase
UniProt: Q9HMF0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 179 (143)
Sequences: 9619 (7348)
Seq/√Len: 614.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
45_S102_R2.9601.00
119_V150_F2.8391.00
112_R147_E2.6601.00
119_V171_V2.6191.00
112_R148_F2.5711.00
129_T170_A2.5301.00
29_R35_D2.5201.00
81_V118_G2.5201.00
29_R70_E2.4571.00
152_Y155_R2.2231.00
116_S148_F2.1181.00
152_Y167_G2.0661.00
78_A105_R2.0561.00
119_V130_V2.0551.00
31_A39_I1.9941.00
153_I170_A1.9561.00
146_E152_Y1.8931.00
37_L53_Y1.8891.00
117_R120_A1.7791.00
142_R146_E1.7691.00
137_S164_E1.7531.00
83_G118_G1.7411.00
143_H146_E1.7331.00
106_Q140_V1.7151.00
79_G101_V1.7041.00
155_R165_D1.6921.00
136_E165_D1.6871.00
115_L148_F1.5711.00
121_A124_G1.5681.00
132_L145_Y1.5491.00
40_V44_Q1.5371.00
45_S103_S1.5321.00
94_G122_L1.5071.00
136_E167_G1.4951.00
29_R71_Q1.4931.00
101_V110_I1.4921.00
105_R108_D1.4921.00
46_V100_A1.4841.00
69_A110_I1.3721.00
38_A41_R1.3651.00
53_Y57_E1.3331.00
121_A125_Q1.2921.00
136_E155_R1.2901.00
153_I168_V1.2571.00
141_A145_Y1.2341.00
38_A77_V1.2151.00
76_S104_T1.1801.00
112_R116_S1.1691.00
123_A171_V1.1631.00
107_G140_V1.1471.00
33_R57_E1.1411.00
135_R164_E1.1361.00
68_A77_V1.1191.00
142_R152_Y1.1181.00
76_S102_R1.1151.00
83_G122_L1.1121.00
40_V53_Y1.1071.00
67_V117_R1.1051.00
139_E142_R1.0921.00
71_Q74_L1.0841.00
133_E166_A1.0801.00
152_Y169_M1.0681.00
85_T127_A1.0621.00
55_A59_Q1.0541.00
157_P165_D1.0511.00
86_I91_R1.0501.00
139_E143_H1.0391.00
28_V113_L1.0381.00
28_V117_R1.0341.00
71_Q78_A1.0311.00
81_V96_I1.0251.00
43_E56_F1.0171.00
47_F100_A1.0071.00
131_K170_A1.0051.00
81_V114_L1.0051.00
92_P128_H0.9951.00
70_E75_D0.9941.00
117_R121_A0.9931.00
41_R45_S0.9881.00
134_V141_A0.9851.00
70_E110_I0.9761.00
129_T172_R0.9691.00
57_E61_D0.9671.00
93_L131_K0.9661.00
122_L130_V0.9651.00
56_F59_Q0.9591.00
31_A68_A0.9571.00
155_R167_G0.9531.00
38_A76_S0.9511.00
52_P55_A0.9421.00
46_V106_Q0.9381.00
109_G112_R0.9361.00
159_Y166_A0.9341.00
33_R61_D0.9321.00
134_V138_N0.9301.00
144_L148_F0.9261.00
42_I102_R0.9171.00
120_A124_G0.9151.00
45_S104_T0.9101.00
43_E80_Y0.9081.00
93_L129_T0.8911.00
113_L116_S0.8891.00
58_R62_T0.8771.00
42_I46_V0.8681.00
142_R167_G0.8641.00
102_R105_R0.8541.00
130_V150_F0.8541.00
42_I77_V0.8291.00
66_L82_V0.8281.00
43_E98_D0.8121.00
41_R102_R0.7981.00
59_Q82_V0.7961.00
36_L40_V0.7941.00
95_H131_K0.7821.00
138_N141_A0.7801.00
151_E170_A0.7801.00
31_A35_D0.7781.00
78_A110_I0.7721.00
26_V110_I0.7631.00
146_E169_M0.7591.00
76_S105_R0.7561.00
37_L41_R0.7521.00
30_Q121_A0.7451.00
151_E172_R0.7431.00
82_V97_K0.7401.00
71_Q105_R0.7401.00
85_T125_Q0.7391.00
35_D70_E0.7371.00
160_Y166_A0.7351.00
63_A70_E0.7301.00
132_L141_A0.7281.00
84_D97_K0.7261.00
43_E47_F0.7231.00
146_E151_E0.7161.00
81_V99_I0.7121.00
131_K153_I0.7111.00
66_L69_A0.7071.00
122_L127_A0.7051.00
94_G127_A0.7041.00
31_A66_L0.7031.00
54_A58_R0.7021.00
142_R169_M0.6901.00
32_T35_D0.6861.00
129_T153_I0.6791.00
107_G143_H0.6671.00
82_V98_D0.6661.00
133_E156_L0.6611.00
80_Y100_A0.6591.00
69_A114_L0.6581.00
41_R76_S0.6541.00
58_R61_D0.6531.00
116_S120_A0.6491.00
119_V123_A0.6481.00
139_E146_E0.6481.00
96_I115_L0.6421.00
115_L150_F0.6411.00
136_E164_E0.6411.00
63_A68_A0.6371.00
29_R32_T0.6361.00
115_L144_L0.6291.00
80_Y98_D0.6281.00
40_V56_F0.6271.00
51_W55_A0.6231.00
101_V111_G0.6191.00
51_W56_F0.6181.00
156_L168_V0.6171.00
54_A57_E0.6131.00
65_F125_Q0.6111.00
27_W70_E0.6071.00
119_V148_F0.6071.00
134_V145_Y0.6071.00
113_L117_R0.6061.00
46_V103_S0.5981.00
65_F121_A0.5921.00
38_A42_I0.5881.00
38_A102_R0.5851.00
51_W59_Q0.5821.00
103_S106_Q0.5811.00
140_V143_H0.5751.00
39_I80_Y0.5711.00
36_L60_L0.5711.00
92_P127_A0.5711.00
63_A69_A0.5701.00
26_V113_L0.5691.00
141_A144_L0.5651.00
110_I113_L0.5631.00
83_G94_G0.5561.00
28_V114_L0.5541.00
69_A77_V0.5531.00
70_E77_V0.5511.00
65_F69_A0.5440.99
67_V82_V0.5440.99
56_F80_Y0.5430.99
93_L156_L0.5400.99
36_L57_E0.5330.99
56_F60_L0.5280.99
99_I115_L0.5270.99
69_A79_G0.5260.99
59_Q62_T0.5250.99
47_F80_Y0.5240.99
107_G111_G0.5230.99
26_V69_A0.5220.99
42_I100_A0.5210.99
89_H92_P0.5210.99
86_I93_L0.5210.99
101_V114_L0.5160.99
56_F82_V0.5150.99
55_A58_R0.5140.99
33_R36_L0.5140.99
84_D95_H0.5090.99
31_A36_L0.5060.99
158_E165_D0.5030.99
63_A66_L0.5020.99
90_G93_L0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ob0A 1 0.8771 99.9 0.368 Contact Map
4kvxA 1 0.8212 99.9 0.372 Contact Map
2reeA 1 0.8436 99.9 0.392 Contact Map
2r7hA 2 0.8212 99.9 0.396 Contact Map
4pv6C 3 0.8603 99.9 0.402 Contact Map
3kkwA 1 0.8603 99.9 0.407 Contact Map
4r3lA 1 0.8212 99.9 0.408 Contact Map
2cntA 1 0.8268 99.9 0.408 Contact Map
3dr6A 2 0.8547 99.9 0.412 Contact Map
1mk4A 2 0.8156 99.9 0.413 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0072 seconds.