GREMLIN Database
Q9HME9 - Uncharacterized protein
UniProt: Q9HME9 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 119 (102)
Sequences: 107 (104)
Seq/√Len: 10.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
30_G33_H3.8280.98
9_G18_L2.6590.88
9_G22_V2.5590.86
3_Y15_G2.3560.81
5_C8_C2.3230.80
16_E23_A2.2960.79
88_A92_D2.1420.74
4_L19_A2.1360.73
5_C21_H2.0820.71
8_C21_H2.0820.71
14_D26_A1.9930.68
29_R33_H1.9040.64
100_E104_A1.7290.56
4_L24_F1.6700.54
46_D54_D1.6520.53
23_A31_G1.6410.52
7_V37_L1.6310.52
6_P24_F1.5450.48
96_A103_A1.5210.47
13_A17_H1.5090.46
99_R104_A1.4900.45
73_T76_A1.4760.45
50_A57_V1.4270.42
19_A22_V1.4020.41
19_A27_L1.3870.41
33_H46_D1.3610.40
8_C25_T1.3520.39
5_C25_T1.3520.39
17_H24_F1.3240.38
59_H94_V1.2910.36
6_P10_V1.2860.36
3_Y23_A1.2750.36
63_T77_P1.2630.35
4_L12_T1.2450.34
28_T31_G1.1630.31
4_L13_A1.1590.31
3_Y16_E1.1550.31
11_E20_N1.1510.31
14_D19_A1.1500.31
7_V24_F1.1190.29
8_C12_T1.1140.29
5_C12_T1.1140.29
9_G19_A1.0880.28
29_R53_A1.0800.28
28_T34_E1.0580.27
18_L25_T1.0580.27
20_N23_A1.0410.26
7_V16_E1.0380.26
42_P58_G1.0360.26
7_V18_L1.0320.26
10_V13_A1.0270.26
32_D55_T1.0200.26
14_D38_D1.0190.26
17_H38_D1.0150.26
93_D102_T1.0000.25
95_L103_A0.9970.25
17_H31_G0.9830.24
80_A83_S0.9670.24
70_E96_A0.9660.24
101_L104_A0.9540.23
64_D81_R0.9450.23
51_E92_D0.9420.23
47_S57_V0.9350.23
23_A42_P0.9170.22
21_H25_T0.9030.22
20_N83_S0.9010.22
18_L26_A0.8960.22
24_F40_H0.8960.22
71_A79_G0.8810.21
67_P81_R0.8750.21
33_H36_W0.8700.21
70_E85_D0.8690.21
14_D18_L0.8680.21
15_G19_A0.8650.21
12_T19_A0.8620.21
64_D72_H0.8520.20
22_V73_T0.8390.20
68_V72_H0.8380.20
50_A82_A0.8380.20
90_D93_D0.8370.20
29_R82_A0.8310.20
7_V14_D0.8290.20
5_C18_L0.8280.20
8_C18_L0.8280.20
25_T90_D0.8140.19
3_Y8_C0.8140.19
79_G83_S0.8080.19
66_E72_H0.8040.19
56_V103_A0.7830.18
4_L17_H0.7790.18
39_E61_T0.7780.18
64_D76_A0.7780.18
9_G15_G0.7760.18
4_L71_A0.7740.18
51_E70_E0.7740.18
20_N80_A0.7690.18
88_A98_A0.7640.18
81_R85_D0.7580.18
86_A92_D0.7560.18
6_P29_R0.7470.17
70_E74_H0.7460.17
100_E103_A0.7340.17
87_S91_S0.7330.17
48_G87_S0.7320.17
10_V32_D0.7220.17
33_H75_D0.7110.16
40_H67_P0.7060.16
43_A53_A0.6900.16
98_A103_A0.6870.16
47_S69_S0.6850.16
83_S97_E0.6820.16
13_A22_V0.6770.15
15_G38_D0.6770.15
13_A91_S0.6600.15
70_E87_S0.6480.15
89_A95_L0.6470.15
26_A34_E0.6360.15
70_E84_V0.6330.14
67_P84_V0.6330.14
3_Y25_T0.6300.14
68_V79_G0.6160.14
73_T83_S0.6130.14
35_A59_H0.5990.14
74_H84_V0.5980.14
99_R102_T0.5950.14
66_E86_A0.5910.14
10_V46_D0.5860.13
93_D97_E0.5800.13
56_V69_S0.5790.13
41_A99_R0.5730.13
67_P79_G0.5650.13
38_D87_S0.5630.13
11_E99_R0.5610.13
97_E100_E0.5600.13
9_G13_A0.5560.13
7_V10_V0.5530.13
59_H101_L0.5530.13
47_S82_A0.5460.13
43_A91_S0.5430.13
12_T21_H0.5420.12
36_W46_D0.5340.12
53_A70_E0.5330.12
6_P11_E0.5250.12
6_P17_H0.5240.12
58_G78_A0.5240.12
4_L86_A0.5220.12
4_L10_V0.5190.12
35_A62_E0.5160.12
62_E74_H0.5160.12
62_E68_V0.5150.12
32_D38_D0.5110.12
15_G60_A0.5100.12
3_Y53_A0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1njqA 1 0.2857 98.7 0.564 Contact Map
2eoxA 1 0.2857 98.7 0.567 Contact Map
2eluA 1 0.2437 98.7 0.568 Contact Map
2el5A 1 0.2857 98.7 0.568 Contact Map
1x3cA 1 0.3782 98.7 0.568 Contact Map
2eouA 1 0.2857 98.7 0.568 Contact Map
2eonA 1 0.3025 98.7 0.569 Contact Map
2yu5A 1 0.2857 98.7 0.569 Contact Map
2ytdA 1 0.3025 98.7 0.57 Contact Map
2embA 1 0.2857 98.7 0.57 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0053 seconds.