Q9HME7 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HME7 - Iron-dependent repressor homolog

UniProt:	Q9HME7	Sequences: MPAATVSRADNRYLTAIFIVGTVEDCRAETGAVAAELDVSPSTVTERFRDLAARDLVDYERYQGATLTDRGERIARTLAWKRCLAHHFSADELDLPADTADELGGALSADAAAALREHIDHPCEGGCRAPAVRLPECTVYSTASR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	145 (117)
Sequences:	2570 (1743)
Seq/√Len:	161.1

ECOLI - MNTR
BACSU - MNTR
HALSA - Q9HME7 Q9HRU8 Q9HRV3 Q9HR69
SULSO - Q7LXP0 Q97WF3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
72_E	76_R	2.813	1.00
89_S	103_L	2.682	1.00
99_T	108_S	2.594	1.00
15_T	82_R	2.570	1.00
10_D	54_R	2.379	1.00
9_A	43_T	2.379	1.00
80_W	116_R	2.310	1.00
58_D	66_T	2.268	1.00
30_T	44_V	2.249	1.00
17_I	57_V	2.220	1.00
11_N	105_G	1.972	1.00
114_A	117_E	1.912	1.00
90_A	97_A	1.903	1.00
77_T	109_A	1.827	1.00
48_F	57_V	1.785	1.00
21_G	72_E	1.756	1.00
116_R	121_H	1.682	1.00
46_E	50_D	1.666	1.00
52_A	59_Y	1.660	1.00
43_T	47_R	1.618	1.00
87_H	91_D	1.561	1.00
19_I	79_A	1.557	1.00
70_R	73_R	1.546	1.00
56_L	70_R	1.543	1.00
107_L	112_A	1.524	1.00
88_F	93_L	1.524	1.00
69_D	72_E	1.512	1.00
15_T	101_D	1.494	1.00
86_H	90_A	1.488	1.00
85_A	107_L	1.483	1.00
23_V	36_E	1.437	1.00
21_G	28_A	1.434	1.00
102_E	106_A	1.427	1.00
16_A	36_E	1.425	1.00
39_V	44_V	1.421	1.00
11_N	104_G	1.359	1.00
17_I	28_A	1.358	1.00
92_E	118_H	1.353	1.00
117_E	121_H	1.301	1.00
59_Y	62_Y	1.296	1.00
33_V	48_F	1.279	1.00
16_A	33_V	1.251	1.00
7_S	10_D	1.250	1.00
101_D	105_G	1.250	1.00
32_A	35_A	1.241	1.00
48_F	65_A	1.225	1.00
95_L	111_A	1.213	1.00
10_D	47_R	1.146	1.00
45_T	59_Y	1.145	1.00
8_R	12_R	1.143	1.00
119_I	122_P	1.129	1.00
33_V	65_A	1.123	1.00
93_L	114_A	1.119	1.00
12_R	105_G	1.111	1.00
41_P	47_R	1.109	1.00
95_L	99_T	1.103	1.00
19_I	36_E	1.097	1.00
101_D	104_G	1.093	1.00
30_T	48_F	1.090	1.00
57_V	65_A	1.088	0.99
15_T	104_G	1.076	0.99
99_T	111_A	1.062	0.99
82_R	104_G	1.051	0.99
16_A	37_L	1.021	0.99
88_F	92_E	1.011	0.99
31_G	41_P	0.985	0.99
96_P	110_D	0.978	0.99
88_F	118_H	0.966	0.99
14_L	18_F	0.964	0.99
73_R	77_T	0.952	0.99
11_N	78_L	0.951	0.99
30_T	41_P	0.950	0.99
80_W	84_L	0.949	0.99
12_R	101_D	0.914	0.98
77_T	81_K	0.909	0.98
110_D	114_A	0.906	0.98
18_F	79_A	0.894	0.98
88_F	115_L	0.881	0.98
27_R	64_G	0.881	0.98
47_R	50_D	0.881	0.98
109_A	113_A	0.880	0.98
49_R	52_A	0.850	0.97
12_R	104_G	0.844	0.97
14_L	74_I	0.833	0.97
17_I	44_V	0.832	0.97
78_L	81_K	0.822	0.97
21_G	26_C	0.821	0.97
74_I	77_T	0.814	0.96
37_L	47_R	0.807	0.96
55_D	70_R	0.805	0.96
49_R	53_A	0.797	0.96
30_T	45_T	0.789	0.96
7_S	62_Y	0.780	0.95
81_K	109_A	0.774	0.95
58_D	68_T	0.767	0.95
40_S	45_T	0.762	0.95
12_R	15_T	0.762	0.95
88_F	119_I	0.760	0.95
83_C	86_H	0.750	0.94
40_S	46_E	0.745	0.94
18_F	75_A	0.744	0.94
82_R	86_H	0.742	0.94
87_H	115_L	0.728	0.93
10_D	49_R	0.724	0.93
33_V	44_V	0.721	0.93
94_D	114_A	0.718	0.93
82_R	101_D	0.717	0.93
19_I	78_L	0.716	0.93
85_A	111_A	0.714	0.93
25_D	32_A	0.708	0.92
69_D	73_R	0.701	0.92
25_D	62_Y	0.696	0.92
48_F	59_Y	0.694	0.92
100_A	106_A	0.693	0.92
108_S	111_A	0.687	0.91
15_T	19_I	0.676	0.91
20_V	28_A	0.675	0.90
22_T	83_C	0.674	0.90
11_N	15_T	0.674	0.90
70_R	74_I	0.672	0.90
37_L	41_P	0.670	0.90
18_F	22_T	0.669	0.90
86_H	97_A	0.667	0.90
81_K	112_A	0.666	0.90
107_L	111_A	0.666	0.90
82_R	105_G	0.650	0.89
10_D	15_T	0.645	0.88
93_L	118_H	0.643	0.88
9_A	12_R	0.634	0.88
9_A	47_R	0.629	0.87
46_E	49_R	0.628	0.87
85_A	115_L	0.627	0.87
15_T	105_G	0.626	0.87
30_T	59_Y	0.624	0.87
44_V	48_F	0.624	0.87
16_A	19_I	0.618	0.86
99_T	114_A	0.615	0.86
18_F	72_E	0.606	0.85
18_F	76_R	0.602	0.85
29_E	64_G	0.596	0.84
30_T	64_G	0.595	0.84
21_G	27_R	0.589	0.83
31_G	63_Q	0.588	0.83
27_R	66_T	0.587	0.83
99_T	106_A	0.582	0.83
99_T	107_L	0.582	0.83
113_A	116_R	0.577	0.82
79_A	83_C	0.577	0.82
99_T	110_D	0.569	0.81
54_R	70_R	0.567	0.81
28_A	33_V	0.565	0.81
39_V	42_S	0.562	0.81
31_G	46_E	0.560	0.80
103_L	106_A	0.557	0.80
39_V	43_T	0.557	0.80
8_R	28_A	0.556	0.80
85_A	103_L	0.549	0.79
51_L	56_L	0.548	0.79
87_H	122_P	0.542	0.78
87_H	123_C	0.539	0.78
60_E	66_T	0.534	0.77
52_A	63_Q	0.528	0.76
33_V	37_L	0.525	0.76
23_V	26_C	0.522	0.75
84_L	115_L	0.519	0.75
83_C	122_P	0.516	0.75
10_D	78_L	0.516	0.75
7_S	39_V	0.508	0.74
20_V	32_A	0.507	0.73
17_I	33_V	0.507	0.73
39_V	47_R	0.506	0.73
15_T	79_A	0.504	0.73
39_V	46_E	0.504	0.73
10_D	50_D	0.503	0.73
12_R	16_A	0.502	0.73
99_T	102_E	0.500	0.72

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1fx7A	4	0.9655	99.9	0.497	Contact Map
4o5vA	2	0.9448	99.9	0.505	Contact Map
2qq9A	2	0.9103	99.9	0.507	Contact Map
3hrsA	2	0.9379	99.9	0.519	Contact Map
1on2A	2	0.9034	99.7	0.619	Contact Map
2x4hA	3	0.8759	99.7	0.621	Contact Map
2h09A	2	0.8138	99.7	0.642	Contact Map
2p8tA	1	0.8138	99.6	0.654	Contact Map
2fxaA	4	0.8759	99.1	0.743	Contact Map
3u2rA	4	0.7034	99	0.755	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.006 seconds.