GREMLIN Database
Q9HME5 - Uncharacterized protein
UniProt: Q9HME5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 64 (60)
Sequences: 6453 (4774)
Seq/√Len: 616.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
7_T61_T2.7131.00
19_T23_T2.1491.00
21_A58_A2.1331.00
3_E39_T2.0711.00
47_D50_A2.0291.00
3_E41_S1.9831.00
29_T45_T1.7481.00
56_D61_T1.7421.00
30_D43_E1.7341.00
16_Q20_D1.6741.00
22_L40_V1.6681.00
9_M18_V1.6611.00
11_C14_C1.6341.00
6_V9_M1.5631.00
6_V40_V1.5511.00
25_L54_A1.5291.00
15_E35_A1.4691.00
29_T43_E1.3721.00
52_V62_V1.3561.00
53_A57_D1.3141.00
17_T58_A1.2861.00
21_A54_A1.2801.00
44_G47_D1.1531.00
21_A25_L1.1191.00
12_A36_D1.1021.00
10_S17_T1.0841.00
5_T62_V1.0471.00
55_I61_T1.0461.00
33_A40_V1.0371.00
48_T52_V1.0371.00
22_L31_A1.0131.00
50_A53_A1.0061.00
42_Y51_V0.9821.00
12_A15_E0.9771.00
53_A56_D0.9691.00
22_L51_V0.9671.00
23_T31_A0.9661.00
28_V31_A0.9561.00
34_D37_T0.9521.00
28_V51_V0.9471.00
49_D53_A0.9391.00
12_A16_Q0.8931.00
8_D61_T0.8791.00
13_H16_Q0.8581.00
7_T38_D0.8511.00
5_T38_D0.8491.00
54_A58_A0.8461.00
18_V58_A0.8271.00
49_D52_V0.8201.00
44_G51_V0.7921.00
4_L55_I0.7761.00
17_T21_A0.7721.00
35_A38_D0.7511.00
40_V55_I0.7511.00
23_T30_D0.7431.00
18_V55_I0.7211.00
22_L42_Y0.7011.00
8_D55_I0.7011.00
19_T32_T0.6961.00
4_L62_V0.6871.00
31_A35_A0.6861.00
4_L40_V0.6841.00
13_H17_T0.6741.00
4_L52_V0.6731.00
4_L48_T0.6651.00
13_H36_D0.6611.00
9_M33_A0.6571.00
5_T41_S0.6521.00
4_L51_V0.6521.00
15_E19_T0.6491.00
32_T43_E0.6491.00
40_V51_V0.6451.00
52_V56_D0.6351.00
15_E33_A0.6171.00
54_A57_D0.6151.00
40_V62_V0.6051.00
17_T60_Y0.6031.00
52_V61_T0.6011.00
32_T41_S0.6001.00
22_L54_A0.5721.00
26_D46_A0.5701.00
50_A54_A0.5661.00
37_T41_S0.5511.00
27_G45_T0.5501.00
9_M35_A0.5470.99
20_D23_T0.5170.99
44_G48_T0.5150.99
31_A42_Y0.5130.99
19_T33_A0.5050.99
13_H35_A0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2roeA 1 1 99.4 0.224 Contact Map
2ropA 1 1 99.3 0.225 Contact Map
1p6tA 1 1 99.3 0.242 Contact Map
4umwA 1 0 99.3 0.244 Contact Map
2ew9A 1 1 99.3 0.249 Contact Map
1qupA 2 0.9844 99.3 0.255 Contact Map
3j09A 2 1 99.3 0.255 Contact Map
4u9rA 1 0.9375 99.3 0.258 Contact Map
2k2pA 1 0.9844 99.3 0.258 Contact Map
2ofgX 1 1 99.2 0.264 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0074 seconds.