GREMLIN Database
SUI1 - Protein translation factor SUI1 homolog
UniProt: Q9HME3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 97 (84)
Sequences: 902 (575)
Seq/√Len: 62.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
59_D92_K4.4471.00
30_R44_E3.2391.00
36_Y39_E3.2361.00
27_I46_F2.7721.00
49_K52_D2.7541.00
29_I86_E2.5861.00
86_E90_R2.4161.00
57_S70_V2.2851.00
58_S62_S2.1001.00
42_V74_E1.9711.00
69_T76_E1.9411.00
87_D91_N1.9321.00
63_K88_F1.9201.00
57_S75_I1.8151.00
48_P52_D1.7360.99
29_I82_S1.7120.99
59_D63_K1.6710.99
88_F92_K1.6540.99
81_H84_R1.6450.99
26_Q95_N1.5870.99
87_D90_R1.5670.99
63_K84_R1.4990.98
34_R39_E1.4550.98
50_D54_D1.4340.98
55_S59_D1.4330.98
88_F91_N1.3840.97
45_G69_T1.3140.96
59_D88_F1.2920.96
83_G87_D1.2480.95
19_D49_K1.2170.94
41_T85_V1.1990.94
39_E82_S1.1700.93
41_T79_G1.1170.91
30_R42_V1.1080.91
34_R76_E1.1040.91
34_R40_V1.0610.89
66_C81_H1.0590.89
58_S66_C1.0570.89
84_R88_F1.0340.88
64_F77_L1.0120.86
38_K58_S0.9280.81
13_E18_E0.9260.81
16_V19_D0.9250.81
56_L85_V0.9140.80
43_I85_V0.8980.79
63_K91_N0.8920.79
27_I48_P0.8810.78
31_I34_R0.8540.76
70_V76_E0.8140.72
77_L85_V0.8080.71
62_S85_V0.7990.71
37_G64_F0.7950.70
25_Q74_E0.7840.69
56_L75_I0.7800.69
12_E86_E0.7670.67
58_S81_H0.7640.67
21_A56_L0.7470.65
16_V91_N0.7450.65
20_V47_D0.7430.65
31_I82_S0.7400.65
55_S94_F0.7380.64
43_I47_D0.7350.64
30_R83_G0.7280.63
41_T81_H0.7270.63
38_K80_N0.7130.62
40_V76_E0.7120.62
41_T66_C0.7110.62
20_V23_E0.6920.59
36_Y65_A0.6790.58
41_T64_F0.6710.57
81_H85_V0.6710.57
13_E17_C0.6690.57
15_C18_E0.6670.57
46_F52_D0.6590.56
29_I42_V0.6580.56
32_D41_T0.6560.55
38_K72_D0.6520.55
76_E81_H0.6470.54
42_V76_E0.6450.54
64_F84_R0.6360.53
25_Q31_I0.6260.52
58_S84_R0.6240.52
14_L43_I0.6230.52
44_E74_E0.6200.51
90_R94_F0.6160.51
28_E80_N0.6160.51
43_I88_F0.6100.50
12_E15_C0.6070.50
55_S58_S0.6020.49
62_S81_H0.5800.47
53_L70_V0.5790.47
47_D73_G0.5720.46
14_L77_L0.5700.46
28_E44_E0.5690.45
48_P56_L0.5680.45
70_V85_V0.5660.45
24_S62_S0.5650.45
54_D90_R0.5630.45
39_E86_E0.5610.45
33_E45_G0.5600.44
46_F56_L0.5600.44
82_S85_V0.5590.44
60_L93_G0.5550.44
58_S86_E0.5550.44
33_E82_S0.5540.44
23_E48_P0.5530.44
33_E53_L0.5530.44
66_C79_G0.5460.43
29_I85_V0.5450.43
19_D51_V0.5420.42
48_P76_E0.5390.42
19_D48_P0.5390.42
22_K87_D0.5340.41
33_E40_V0.5320.41
65_A77_L0.5290.41
47_D76_E0.5290.41
36_Y61_K0.5230.40
21_A51_V0.5220.40
49_K91_N0.5170.40
86_E91_N0.5150.39
35_R42_V0.5140.39
86_E95_N0.5130.39
28_E34_R0.5110.39
31_I80_N0.5060.38
29_I81_H0.5040.38
62_S66_C0.5000.38
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4mo0A 1 0.7629 100 0.232 Contact Map
1d1rA 1 0.7835 99.9 0.37 Contact Map
2if1A 1 0.9897 99.8 0.458 Contact Map
4kzyl 1 0.7423 99.8 0.469 Contact Map
2oghA 1 0.9794 99.8 0.474 Contact Map
4bpeF 1 0.7835 99.8 0.476 Contact Map
4uerF 1 0.732 99.8 0.484 Contact Map
3j7yg 1 0.9485 99.8 0.504 Contact Map
1vw47 1 0.8351 99.1 0.678 Contact Map
2ausD 2 0.4021 26.9 0.919 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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