Q9HMC2 - HALSA - GREMLIN Contacts

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Q9HMC2 - GTPase HflX

UniProt:	Q9HMC2	Sequences: MTDRRNSTAVVAKRRTDTPIETDEIRALCEAAGVEVVAERTQARPRDPTYDLGDGAVADIAGLVERRSADLVVVDDHLDPGRAHNLQEAVGAEVVDRARLVLDIFGERAETKRARLEVRLAELRYELPRAQARVERGETQGRQGFRSGGERPAAQLKADYRQRITDRRAELDRLDDADDGLREARRESGFDLVALAGYTNAGKSTLLRRLADDLAVDENDGHGDRTDTAASRDRLFETLNTTTRRATVGERRVLLTDTVGFVDDLPRWLLSSFRTTLAAAREADAVLLVVDATDDREGIRAKVEASRDELADAEGTLVPVLNKRDAATDLDAKRRLLAEHAGHAPVVTSATGAEGLDALRERLTDALPDRRRVSLSVPNTDAGNAFVSWCHDRGTVHEPDYGERIAFGFEARPEVTAKATGRAEQLNED	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	429 (370)
Sequences:	3873 (2316)
Seq/√Len:	120.4

ECOLI - HFLX MNME
BACSU - HFLX
HALSA - Q9HMC2
SULSO - HFLX

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
57_V	89_A	4.042	1.00
52_L	60_I	3.800	1.00
287_L	320_V	3.658	1.00
381_D	385_A	3.638	1.00
64_V	92_A	3.628	1.00
124_R	168_R	3.594	1.00
29_C	73_V	3.593	1.00
57_V	86_L	3.308	1.00
44_R	47_D	3.094	1.00
26_R	39_E	3.063	1.00
194_A	283_A	3.038	1.00
23_D	39_E	2.997	1.00
290_V	319_P	2.937	1.00
27_A	30_E	2.867	1.00
243_T	254_L	2.803	1.00
250_E	364_T	2.799	1.00
362_R	365_D	2.712	1.00
245_R	252_R	2.672	1.00
56_A	59_D	2.646	1.00
64_V	72_V	2.608	1.00
72_V	90_V	2.534	1.00
40_R	60_I	2.477	1.00
29_C	34_V	2.403	1.00
38_A	63_L	2.375	1.00
193_V	253_V	2.327	1.00
61_A	65_E	2.299	1.00
76_D	264_D	2.293	1.00
308_D	313_A	2.275	1.00
40_R	63_L	2.263	1.00
209_R	356_L	2.250	1.00
243_T	256_T	2.226	1.00
119_R	163_R	2.214	1.00
318_V	362_R	2.214	1.00
304_E	317_L	2.207	1.00
205_T	350_A	2.062	1.00
320_V	359_L	2.055	1.00
300_R	319_P	2.044	1.00
292_A	321_L	2.033	1.00
285_A	363_L	2.004	1.00
320_V	346_V	1.997	1.00
362_R	366_A	1.995	1.00
103_D	122_E	1.988	1.00
271_S	274_R	1.977	1.00
294_D	299_I	1.976	1.00
116_L	167_R	1.929	1.00
230_A	234_R	1.910	1.00
86_L	90_V	1.890	1.00
267_R	306_S	1.831	1.00
324_R	347_V	1.827	1.00
31_A	108_R	1.826	1.00
172_D	175_D	1.816	1.00
287_L	359_L	1.805	1.00
134_V	137_G	1.795	1.00
166_D	170_E	1.769	1.00
321_L	347_V	1.767	1.00
61_A	89_A	1.753	1.00
301_A	305_A	1.747	1.00
134_V	138_E	1.733	1.00
155_Q	159_D	1.719	1.00
389_W	393_R	1.702	1.00
208_R	231_S	1.684	1.00
52_L	74_V	1.677	1.00
204_S	229_A	1.666	1.00
186_R	282_E	1.633	1.00
175_D	278_A	1.621	1.00
352_G	355_G	1.615	1.00
229_A	242_T	1.614	1.00
175_D	274_R	1.607	1.00
31_A	234_R	1.596	1.00
47_D	54_D	1.593	1.00
290_V	300_R	1.587	1.00
134_V	152_P	1.566	1.00
58_A	62_G	1.565	1.00
140_Q	145_F	1.547	1.00
113_R	178_D	1.538	1.00
72_V	92_A	1.531	1.00
361_E	365_D	1.528	1.00
355_G	358_A	1.527	1.00
18_T	41_T	1.506	1.00
209_R	353_A	1.498	1.00
196_A	286_V	1.484	1.00
391_H	399_P	1.484	1.00
164_I	168_R	1.483	1.00
293_T	326_A	1.482	1.00
344_A	362_R	1.474	1.00
57_V	90_V	1.468	1.00
298_G	301_A	1.462	1.00
64_V	90_V	1.460	1.00
304_E	319_P	1.442	1.00
63_L	67_R	1.427	1.00
328_T	331_D	1.414	1.00
230_A	237_E	1.412	1.00
288_L	303_V	1.410	1.00
29_C	100_L	1.405	1.00
37_V	67_R	1.381	1.00
120_L	164_I	1.377	1.00
305_A	309_E	1.372	1.00
195_L	207_L	1.363	1.00
175_D	275_T	1.342	1.00
281_R	311_A	1.328	1.00
119_R	123_L	1.324	1.00
211_A	246_A	1.324	1.00
193_V	287_L	1.323	1.00
50_Y	57_V	1.320	1.00
51_D	76_D	1.319	1.00
165_T	169_A	1.313	1.00
178_D	278_A	1.294	1.00
58_A	89_A	1.287	1.00
300_R	304_E	1.284	1.00
359_L	363_L	1.280	1.00
112_K	170_E	1.279	1.00
318_V	366_A	1.268	1.00
85_N	88_E	1.268	1.00
124_R	268_W	1.267	1.00
247_T	252_R	1.266	1.00
136_R	152_P	1.265	1.00
38_A	67_R	1.265	1.00
23_D	26_R	1.260	0.99
387_V	399_P	1.254	0.99
34_V	70_D	1.254	0.99
285_A	318_V	1.245	0.99
26_R	30_E	1.240	0.99
62_G	65_E	1.235	0.99
64_V	69_A	1.233	0.99
213_D	228_T	1.228	0.99
249_G	364_T	1.227	0.99
320_V	348_T	1.201	0.99
38_A	69_A	1.182	0.99
109_A	114_A	1.180	0.99
205_T	348_T	1.175	0.99
180_G	183_E	1.174	0.99
132_A	137_G	1.173	0.99
111_T	114_A	1.172	0.99
268_W	309_E	1.166	0.99
122_E	126_E	1.156	0.99
105_F	114_A	1.144	0.99
140_Q	152_P	1.141	0.99
200_N	233_D	1.140	0.99
62_G	66_R	1.129	0.99
25_I	73_V	1.125	0.99
278_A	282_E	1.121	0.99
137_G	156_L	1.121	0.99
95_V	100_L	1.120	0.99
34_V	73_V	1.115	0.99
192_L	254_L	1.114	0.99
177_A	180_G	1.112	0.99
388_S	392_D	1.108	0.99
127_L	161_R	1.106	0.99
34_V	71_L	1.105	0.99
122_E	153_A	1.104	0.99
31_A	262_V	1.100	0.99
193_V	285_A	1.097	0.99
132_A	135_E	1.089	0.99
143_Q	148_G	1.086	0.98
52_L	57_V	1.086	0.98
196_A	280_A	1.085	0.98
116_L	174_L	1.079	0.98
132_A	145_F	1.077	0.98
37_V	69_A	1.076	0.98
19_P	23_D	1.070	0.98
154_A	158_A	1.068	0.98
63_L	69_A	1.067	0.98
182_R	278_A	1.064	0.98
318_V	363_L	1.064	0.98
248_V	253_V	1.061	0.98
305_A	308_D	1.060	0.98
378_P	381_D	1.057	0.98
71_L	93_E	1.039	0.98
105_F	109_A	1.034	0.98
300_R	321_L	1.031	0.98
152_P	159_D	1.028	0.98
267_R	270_L	1.028	0.98
196_A	307_R	1.027	0.98
288_L	300_R	1.026	0.98
358_A	361_E	1.022	0.98
29_C	36_V	1.018	0.98
173_R	176_D	1.017	0.98
132_A	136_R	1.009	0.98
31_A	235_L	1.009	0.98
302_K	306_S	1.002	0.97
184_A	187_E	1.000	0.97
32_A	103_D	0.997	0.97
312_D	315_G	0.995	0.97
61_A	64_V	0.988	0.97
246_A	253_V	0.985	0.97
169_A	172_D	0.985	0.97
246_A	255_L	0.982	0.97
34_V	143_Q	0.980	0.97
106_G	122_E	0.976	0.97
133_R	136_R	0.974	0.97
136_R	159_D	0.971	0.97
346_V	362_R	0.969	0.97
390_C	394_G	0.967	0.97
319_P	345_P	0.965	0.97
177_A	181_L	0.958	0.97
65_E	91_G	0.953	0.97
109_A	113_R	0.953	0.97
32_A	122_E	0.953	0.97
204_S	231_S	0.952	0.96
54_D	58_A	0.948	0.96
212_D	228_T	0.948	0.96
165_T	168_R	0.943	0.96
122_E	148_G	0.942	0.96
288_L	294_D	0.938	0.96
297_E	301_A	0.935	0.96
175_D	271_S	0.934	0.96
150_E	154_A	0.930	0.96
207_L	302_K	0.928	0.96
288_L	317_L	0.927	0.96
372_R	397_H	0.920	0.96
34_V	122_E	0.918	0.96
108_R	230_A	0.916	0.96
150_E	158_A	0.910	0.95
137_G	140_Q	0.909	0.95
397_H	400_D	0.907	0.95
78_L	82_R	0.904	0.95
381_D	386_F	0.899	0.95
344_A	366_A	0.899	0.95
132_A	152_P	0.897	0.95
142_R	145_F	0.896	0.95
60_I	90_V	0.896	0.95
61_A	91_G	0.895	0.95
61_A	90_V	0.894	0.95
124_R	164_I	0.891	0.95
234_R	237_E	0.889	0.95
293_T	327_A	0.889	0.95
58_A	61_A	0.886	0.95
103_D	146_R	0.886	0.95
138_E	152_P	0.885	0.95
274_R	278_A	0.882	0.95
169_A	173_R	0.881	0.95
107_E	114_A	0.881	0.95
21_E	264_D	0.879	0.95
30_E	36_V	0.877	0.94
330_L	333_K	0.876	0.94
233_D	326_A	0.872	0.94
34_V	103_D	0.869	0.94
249_G	360_R	0.866	0.94
210_L	360_R	0.864	0.94
75_D	264_D	0.863	0.94
302_K	305_A	0.861	0.94
376_S	379_N	0.861	0.94
19_P	39_E	0.859	0.94
22_T	25_I	0.854	0.94
391_H	396_V	0.853	0.94
50_Y	54_D	0.849	0.93
179_D	186_R	0.842	0.93
162_Q	166_D	0.840	0.93
134_V	139_T	0.840	0.93
88_E	91_G	0.839	0.93
376_S	402_G	0.835	0.93
123_L	160_Y	0.833	0.93
398_E	402_G	0.830	0.93
134_V	159_D	0.830	0.93
251_R	368_P	0.829	0.93
329_D	332_A	0.827	0.93
93_E	103_D	0.826	0.93
329_D	333_K	0.825	0.92
106_G	148_G	0.824	0.92
274_R	309_E	0.824	0.92
228_T	232_R	0.824	0.92
232_R	237_E	0.823	0.92
77_H	268_W	0.822	0.92
79_D	82_R	0.822	0.92
140_Q	151_R	0.822	0.92
31_A	230_A	0.821	0.92
20_I	296_R	0.818	0.92
105_F	108_R	0.818	0.92
387_V	391_H	0.816	0.92
26_R	36_V	0.816	0.92
377_V	386_F	0.815	0.92
366_A	369_D	0.813	0.92
22_T	39_E	0.812	0.92
207_L	255_L	0.812	0.92
113_R	174_L	0.808	0.92
348_T	356_L	0.795	0.91
146_R	153_A	0.791	0.91
105_F	111_T	0.785	0.90
33_G	107_E	0.784	0.90
120_L	167_R	0.783	0.90
104_I	114_A	0.779	0.90
35_E	39_E	0.778	0.90
32_A	106_G	0.778	0.90
138_E	145_F	0.777	0.90
190_F	254_L	0.776	0.90
353_A	356_L	0.773	0.90
183_E	187_E	0.771	0.90
97_R	109_A	0.770	0.90
357_D	361_E	0.768	0.90
100_L	104_I	0.768	0.90
332_A	347_V	0.766	0.89
321_L	345_P	0.763	0.89
132_A	138_E	0.762	0.89
31_A	232_R	0.762	0.89
389_W	392_D	0.762	0.89
209_R	351_T	0.760	0.89
140_Q	143_Q	0.760	0.89
162_Q	165_T	0.757	0.89
104_I	109_A	0.756	0.89
397_H	401_Y	0.754	0.89
87_Q	93_E	0.752	0.89
191_D	367_L	0.749	0.88
195_L	206_L	0.747	0.88
280_A	286_V	0.742	0.88
292_A	327_A	0.742	0.88
35_E	68_S	0.742	0.88
103_D	107_E	0.741	0.88
81_G	84_H	0.741	0.88
211_A	228_T	0.740	0.88
135_E	138_E	0.739	0.88
385_A	389_W	0.739	0.88
168_R	271_S	0.738	0.88
193_V	366_A	0.733	0.87
280_A	283_A	0.732	0.87
361_E	364_T	0.731	0.87
22_T	41_T	0.731	0.87
73_V	100_L	0.730	0.87
326_A	351_T	0.728	0.87
327_A	332_A	0.727	0.87
207_L	229_A	0.720	0.86
306_S	310_L	0.718	0.86
332_A	354_E	0.714	0.86
176_D	180_G	0.714	0.86
82_R	85_N	0.713	0.86
34_V	93_E	0.712	0.86
138_E	141_G	0.711	0.86
384_N	390_C	0.710	0.86
101_V	104_I	0.708	0.85
136_R	140_Q	0.706	0.85
114_A	148_G	0.704	0.85
301_A	304_E	0.701	0.85
21_E	44_R	0.700	0.85
27_A	263_D	0.697	0.84
51_D	74_V	0.694	0.84
53_G	56_A	0.692	0.84
40_R	69_A	0.692	0.84
184_A	188_S	0.691	0.84
193_V	363_L	0.690	0.84
204_S	255_L	0.689	0.84
18_T	39_E	0.688	0.84
172_D	176_D	0.687	0.84
50_Y	89_A	0.686	0.84
24_E	28_L	0.686	0.84
40_R	67_R	0.685	0.83
42_Q	56_A	0.685	0.83
131_Q	134_V	0.682	0.83
375_L	378_P	0.682	0.83
114_A	241_T	0.679	0.83
17_D	20_I	0.678	0.83
25_I	74_V	0.678	0.83
126_E	133_R	0.677	0.83
21_E	27_A	0.676	0.83
170_E	271_S	0.673	0.82
391_H	394_G	0.671	0.82
128_P	207_L	0.670	0.82
105_F	112_K	0.669	0.82
27_A	31_A	0.669	0.82
332_A	337_L	0.668	0.82
396_V	402_G	0.668	0.82
18_T	43_A	0.668	0.82
251_R	364_T	0.667	0.82
324_R	354_E	0.666	0.82
113_R	272_S	0.666	0.82
326_A	329_D	0.666	0.82
211_A	253_V	0.665	0.82
307_R	310_L	0.661	0.81
106_G	114_A	0.659	0.81
181_L	271_S	0.659	0.81
127_L	131_Q	0.659	0.81
107_E	111_T	0.659	0.81
93_E	122_E	0.658	0.81
376_S	400_D	0.656	0.81
23_D	326_A	0.654	0.81
32_A	107_E	0.654	0.81
168_R	172_D	0.654	0.81
132_A	140_Q	0.653	0.80
153_A	156_L	0.653	0.80
178_D	272_S	0.653	0.80
171_L	174_L	0.652	0.80
140_Q	146_R	0.648	0.80
338_A	341_A	0.647	0.80
21_E	263_D	0.647	0.80
153_A	157_K	0.645	0.80
328_T	333_K	0.645	0.80
114_A	272_S	0.644	0.80
68_S	173_R	0.643	0.79
294_D	297_E	0.641	0.79
240_N	269_L	0.641	0.79
377_V	384_N	0.639	0.79
83_A	99_R	0.638	0.79
290_V	304_E	0.637	0.79
31_A	195_L	0.637	0.79
297_E	335_R	0.636	0.79
133_R	140_Q	0.635	0.79
173_R	177_A	0.635	0.79
281_R	315_G	0.634	0.78
97_R	104_I	0.634	0.78
377_V	381_D	0.633	0.78
25_I	36_V	0.631	0.78
384_N	388_S	0.630	0.78
103_D	106_G	0.627	0.78
148_G	152_P	0.622	0.77
246_A	360_R	0.620	0.77
200_N	232_R	0.619	0.77
206_L	348_T	0.617	0.77
122_E	155_Q	0.613	0.76
130_A	157_K	0.613	0.76
160_Y	164_I	0.613	0.76
134_V	148_G	0.611	0.76
21_E	25_I	0.609	0.76
177_A	231_S	0.608	0.76
379_N	401_Y	0.607	0.75
353_A	357_D	0.607	0.75
20_I	294_D	0.606	0.75
106_G	146_R	0.606	0.75
231_S	234_R	0.606	0.75
290_V	321_L	0.604	0.75
134_V	145_F	0.604	0.75
144_G	148_G	0.604	0.75
352_G	357_D	0.603	0.75
401_Y	404_R	0.602	0.75
375_L	386_F	0.600	0.75
197_G	260_G	0.600	0.75
84_H	87_Q	0.599	0.74
306_S	309_E	0.597	0.74
192_L	280_A	0.596	0.74
193_V	255_L	0.596	0.74
367_L	395_T	0.594	0.74
20_I	26_R	0.592	0.74
242_T	391_H	0.592	0.74
241_T	255_L	0.592	0.74
182_R	279_A	0.591	0.73
139_T	142_R	0.590	0.73
213_D	229_A	0.589	0.73
385_A	388_S	0.589	0.73
159_D	162_Q	0.589	0.73
131_Q	141_G	0.589	0.73
138_E	146_R	0.588	0.73
104_I	111_T	0.587	0.73
145_F	248_V	0.586	0.73
74_V	78_L	0.584	0.73
376_S	404_R	0.583	0.72
78_L	85_N	0.583	0.72
98_A	113_R	0.582	0.72
42_Q	127_L	0.581	0.72
342_G	345_P	0.579	0.72
37_V	70_D	0.577	0.72
104_I	108_R	0.575	0.71
291_D	323_K	0.574	0.71
78_L	96_D	0.573	0.71
379_N	402_G	0.573	0.71
282_E	351_T	0.572	0.71
130_A	153_A	0.571	0.71
393_R	403_E	0.570	0.71
135_E	139_T	0.570	0.71
195_L	229_A	0.569	0.71
123_L	164_I	0.568	0.71
27_A	271_S	0.564	0.70
61_A	92_A	0.564	0.70
328_T	332_A	0.563	0.70
394_G	399_P	0.563	0.70
132_A	156_L	0.561	0.70
357_D	360_R	0.560	0.69
240_N	303_V	0.558	0.69
70_D	275_T	0.558	0.69
31_A	126_E	0.557	0.69
81_G	85_N	0.557	0.69
251_R	371_R	0.557	0.69
140_Q	148_G	0.557	0.69
251_R	367_L	0.556	0.69
60_I	64_V	0.556	0.69
129_R	138_E	0.556	0.69
74_V	83_A	0.554	0.69
42_Q	53_G	0.554	0.69
398_E	401_Y	0.553	0.68
195_L	201_A	0.553	0.68
165_T	173_R	0.553	0.68
53_G	78_L	0.552	0.68
152_P	208_R	0.550	0.68
289_V	348_T	0.550	0.68
113_R	278_A	0.549	0.68
36_V	66_R	0.549	0.68
204_S	230_A	0.548	0.68
17_D	298_G	0.546	0.68
80_P	83_A	0.544	0.67
108_R	114_A	0.541	0.67
47_D	51_D	0.541	0.67
49_T	81_G	0.541	0.67
212_D	385_A	0.539	0.67
23_D	187_E	0.539	0.67
386_F	393_R	0.539	0.67
95_V	103_D	0.538	0.66
46_R	247_T	0.537	0.66
99_R	128_P	0.536	0.66
246_A	363_L	0.535	0.66
151_R	155_Q	0.534	0.66
358_A	362_R	0.534	0.66
248_V	364_T	0.534	0.66
42_Q	128_P	0.533	0.66
348_T	352_G	0.532	0.66
132_A	159_D	0.532	0.66
85_N	90_V	0.532	0.66
321_L	342_G	0.532	0.66
288_L	319_P	0.531	0.65
77_H	98_A	0.531	0.65
64_V	67_R	0.531	0.65
137_G	141_G	0.530	0.65
139_T	152_P	0.530	0.65
88_E	92_A	0.529	0.65
120_L	240_N	0.529	0.65
25_I	31_A	0.529	0.65
269_L	272_S	0.529	0.65
131_Q	157_K	0.528	0.65
57_V	61_A	0.527	0.65
97_R	101_V	0.526	0.65
312_D	317_L	0.525	0.65
207_L	231_S	0.524	0.64
80_P	117_E	0.523	0.64
360_R	364_T	0.523	0.64
396_V	399_P	0.520	0.64
379_N	384_N	0.519	0.64
253_V	363_L	0.519	0.64
391_H	401_Y	0.519	0.64
140_Q	155_Q	0.518	0.64
311_A	315_G	0.518	0.64
18_T	75_D	0.517	0.63
63_L	66_R	0.517	0.63
63_L	313_A	0.517	0.63
102_L	105_F	0.516	0.63
137_G	152_P	0.516	0.63
384_N	387_V	0.515	0.63
106_G	109_A	0.515	0.63
261_F	310_L	0.514	0.63
99_R	153_A	0.514	0.63
31_A	103_D	0.512	0.63
393_R	402_G	0.512	0.63
41_T	65_E	0.512	0.63
281_R	312_D	0.512	0.63
50_Y	85_N	0.512	0.63
202_G	260_G	0.511	0.62
80_P	90_V	0.510	0.62
267_R	309_E	0.509	0.62
231_S	275_T	0.509	0.62
246_A	262_V	0.509	0.62
292_A	324_R	0.507	0.62
114_A	208_R	0.506	0.62
299_I	303_V	0.505	0.62
348_T	359_L	0.504	0.61
377_V	387_V	0.503	0.61
206_L	356_L	0.503	0.61
327_A	331_D	0.503	0.61
237_E	269_L	0.502	0.61
348_T	351_T	0.502	0.61
93_E	180_G	0.501	0.61
331_D	361_E	0.500	0.61

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2qtfA	1	0.6993	100	0.377	Contact Map
3gehA	2	0.8625	100	0.587	Contact Map
3geeA	2	0.8228	100	0.589	Contact Map
1xzpA	4	0.9324	100	0.595	Contact Map
3j65o	1	0.7436	100	0.665	Contact Map
2e87A	1	0.7855	100	0.728	Contact Map
2qm8A	2	0.6014	100	0.73	Contact Map
2j69A	1	0.6294	100	0.733	Contact Map
4xc8A	2	0.8974	100	0.743	Contact Map
1egaA	2	0.5268	100	0.746	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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