GREMLIN Database
Q9HMC1 - RNase L inhibitor homolog
UniProt: Q9HMC1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 610 (534)
Sequences: 273 (159)
Seq/√Len: 6.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
367_F374_G6.5041.00
376_I379_N6.4191.00
367_F379_N5.3970.99
367_F372_E5.3370.99
374_G379_N5.2020.99
551_P557_A4.7230.99
367_F371_V4.5760.98
371_V374_G4.5620.98
367_F376_I4.3000.97
372_E379_N4.0860.96
549_G557_A3.9520.95
183_P188_G3.6850.93
177_Q180_D3.5280.91
372_E376_I3.5220.91
370_S374_G3.3860.90
548_D557_A3.2920.88
371_V379_N3.2210.87
175_K179_V2.9970.83
175_K180_D2.9890.83
336_I339_E2.9470.82
370_S379_N2.9170.81
367_F370_S2.8990.80
549_G553_E2.8670.80
31_R529_V2.8540.79
175_K178_Y2.7420.76
208_D213_R2.7190.76
56_E59_C2.6990.75
176_P179_V2.6840.75
374_G378_R2.5310.70
370_S376_I2.4370.67
177_Q182_I2.3570.64
175_K182_I2.3510.64
371_V376_I2.3500.64
548_D551_P2.3480.64
56_E61_G2.2980.62
178_Y183_P2.2800.62
321_R547_F2.2630.61
374_G377_N2.2300.60
549_G552_A2.2190.59
139_R148_E2.1920.58
363_G379_N2.1890.58
177_Q183_P2.1510.57
21_Y41_G2.1420.57
365_G374_G2.0900.55
197_T295_V2.0720.54
176_P180_D2.0440.53
18_R22_E2.0410.53
432_D487_T2.0140.52
83_Q321_R2.0110.52
181_E422_I2.0020.51
339_E342_A1.9900.51
336_I342_A1.9790.50
176_P182_I1.9720.50
54_I59_C1.9710.50
363_G374_G1.9710.50
551_P554_H1.9690.50
368_T376_I1.9590.50
332_R338_F1.9550.50
338_F342_A1.9480.49
554_H557_A1.9340.49
30_N52_V1.9270.48
363_G367_F1.9190.48
182_I232_A1.9150.48
117_P120_I1.8670.46
179_V182_I1.8530.46
58_I61_G1.8480.45
360_K379_N1.8430.45
368_T374_G1.8390.45
360_K363_G1.8070.44
553_E557_A1.8040.44
341_H344_R1.8000.44
18_R73_F1.7890.43
338_F341_H1.7850.43
35_E38_T1.7790.43
396_A496_L1.7760.43
89_P484_I1.7740.43
180_D183_P1.7440.42
341_H345_S1.7340.41
183_P186_F1.7290.41
206_L264_L1.7290.41
368_T379_N1.7270.41
195_E203_L1.7190.41
360_K367_F1.7180.41
331_V336_I1.7170.41
30_N38_T1.7130.40
551_P555_G1.6900.40
549_G554_H1.6890.40
54_I61_G1.6860.39
239_R428_Y1.6720.39
363_G372_E1.6630.39
17_D52_V1.6620.39
110_K430_E1.6460.38
183_P187_D1.6460.38
552_A557_A1.6400.38
456_E522_N1.6380.38
445_T448_V1.6370.38
83_Q95_E1.6340.38
367_F378_R1.6320.38
83_Q110_K1.6260.37
367_F377_N1.6250.37
385_V396_A1.6210.37
549_G555_G1.6110.37
550_E557_A1.6040.37
57_E467_M1.6030.36
110_K510_V1.6030.36
444_V448_V1.5940.36
240_D274_K1.5550.35
12_D15_Q1.5500.35
52_V58_I1.5500.35
83_Q424_Y1.5430.34
336_I340_E1.5230.34
432_D435_M1.5160.33
339_E343_P1.5110.33
175_K183_P1.4890.33
207_V216_M1.4840.32
380_E543_R1.4830.32
372_E377_N1.4810.32
371_V378_R1.4640.32
360_K374_G1.4610.32
307_T481_R1.4370.31
332_R336_I1.4220.30
26_Y30_N1.4100.30
188_G424_Y1.4080.30
20_N35_E1.4020.30
442_S458_A1.4020.30
207_V213_R1.3970.30
198_D202_V1.3950.30
315_G507_E1.3940.29
277_L284_A1.3800.29
56_E60_L1.3710.29
110_K432_D1.3570.28
191_R203_L1.3490.28
13_R41_G1.3480.28
83_Q94_G1.3460.28
295_V419_G1.3450.28
13_R20_N1.3430.28
368_T373_G1.3310.28
454_Q458_A1.3310.28
295_V310_K1.3220.27
198_D201_G1.3220.27
21_Y30_N1.3200.27
390_I525_S1.3160.27
362_Y374_G1.3020.27
237_L264_L1.2960.26
32_T165_V1.2900.26
49_P108_S1.2830.26
21_Y52_V1.2800.26
110_K513_T1.2760.26
191_R195_E1.2750.26
302_V310_K1.2720.26
367_F373_G1.2660.26
362_Y379_N1.2640.26
389_G536_M1.2580.25
422_I547_F1.2560.25
434_Q472_P1.2500.25
54_I58_I1.2490.25
87_D484_I1.2480.25
234_A238_A1.2470.25
88_Q485_A1.2420.25
551_P556_Q1.2260.24
340_E343_P1.2200.24
442_S446_D1.2170.24
290_A531_D1.2140.24
140_H408_V1.2120.24
9_V482_V1.2100.24
9_V31_R1.2080.24
397_Q424_Y1.2080.24
365_G372_E1.2070.24
194_L215_V1.2070.24
420_L455_T1.2060.24
178_Y182_I1.2060.24
270_E274_K1.2000.24
372_E378_R1.1990.24
255_I547_F1.1980.24
396_A424_Y1.1900.23
88_Q189_N1.1900.23
52_V56_E1.1900.23
94_G188_G1.1870.23
84_E321_R1.1830.23
181_E547_F1.1790.23
220_I463_L1.1690.23
73_F484_I1.1660.23
20_N73_F1.1630.23
368_T372_E1.1590.23
207_V380_E1.1590.23
439_A487_T1.1590.23
336_I343_P1.1510.22
269_A276_V1.1480.22
424_Y442_S1.1450.22
18_R511_L1.1440.22
22_E35_E1.1380.22
550_E553_E1.1380.22
193_L235_A1.1370.22
55_S543_R1.1330.22
350_D464_D1.1330.22
278_V397_Q1.1310.22
552_A555_G1.1270.22
16_P19_C1.1190.22
14_C19_C1.1190.22
458_A529_V1.1170.22
94_G323_Y1.1020.21
177_Q188_G1.0970.21
53_H408_V1.0950.21
183_P424_Y1.0880.21
550_E554_H1.0870.21
301_S466_I1.0810.21
336_I341_H1.0740.20
452_Y522_N1.0730.20
342_A345_S1.0700.20
243_F260_T1.0650.20
444_V447_D1.0640.20
337_E342_A1.0620.20
338_F343_P1.0620.20
181_E494_L1.0590.20
308_P461_L1.0580.20
207_V250_T1.0580.20
362_Y367_F1.0520.20
186_F424_Y1.0510.20
270_E273_D1.0450.20
293_I484_I1.0400.20
83_Q310_K1.0390.20
219_A222_S1.0370.20
25_N461_L1.0360.20
20_N26_Y1.0310.19
340_E345_S1.0250.19
167_D410_G1.0210.19
365_G379_N1.0210.19
339_E344_R1.0210.19
55_S61_G1.0190.19
22_E73_F1.0130.19
233_L405_P1.0080.19
19_C27_C1.0060.19
16_P28_P1.0060.19
19_C28_P1.0060.19
14_C27_C1.0060.19
16_P27_C1.0060.19
14_C28_P1.0060.19
23_C27_C1.0030.19
23_C28_P1.0030.19
397_Q450_T1.0010.19
493_D507_E1.0000.19
35_E470_R1.0000.19
361_S369_L0.9980.19
176_P188_G0.9950.19
330_R334_E0.9930.19
110_K431_A0.9900.18
10_D20_N0.9890.18
366_E374_G0.9840.18
398_L513_T0.9790.18
339_E346_A0.9740.18
371_V377_N0.9720.18
94_G260_T0.9710.18
83_Q547_F0.9690.18
206_L238_A0.9630.18
20_N30_N0.9570.18
26_Y41_G0.9550.18
38_T53_H0.9530.18
398_L424_Y0.9500.18
339_E345_S0.9490.18
20_N52_V0.9430.17
363_G370_S0.9430.17
25_N473_D0.9410.17
369_L379_N0.9390.17
66_I289_L0.9360.17
86_D346_A0.9350.17
261_A481_R0.9330.17
165_V186_F0.9320.17
21_Y26_Y0.9320.17
162_L262_A0.9310.17
421_D493_D0.9300.17
11_L51_Q0.9270.17
370_S377_N0.9250.17
341_H347_S0.9220.17
366_E373_G0.9160.17
368_T371_V0.9150.17
344_R354_S0.9130.17
10_D18_R0.9130.17
484_I490_K0.9130.17
83_Q323_Y0.9130.17
127_D266_R0.9110.17
548_D555_G0.9110.17
446_D454_Q0.9110.17
229_Q480_Q0.9110.17
343_P347_S0.9090.17
552_A556_Q0.9070.17
154_R159_Q0.9060.17
209_R361_S0.9010.17
537_I544_L0.8990.16
323_Y490_K0.8980.16
11_L38_T0.8970.16
334_E339_E0.8970.16
19_C23_C0.8940.16
16_P23_C0.8940.16
14_C23_C0.8940.16
369_L376_I0.8920.16
458_A467_M0.8920.16
52_V59_C0.8910.16
289_L507_E0.8900.16
32_T344_R0.8890.16
112_T389_G0.8880.16
160_D172_V0.8870.16
89_P396_A0.8860.16
244_Y300_P0.8850.16
307_T400_A0.8850.16
25_N38_T0.8830.16
338_F345_S0.8790.16
173_A274_K0.8770.16
89_P424_Y0.8750.16
257_Q331_V0.8730.16
52_V61_G0.8730.16
206_L439_A0.8690.16
360_K372_E0.8680.16
164_A321_R0.8670.16
165_V198_D0.8670.16
35_E39_L0.8650.16
375_D408_V0.8630.16
360_K365_G0.8620.16
141_E484_I0.8600.16
364_D411_E0.8590.16
310_K326_N0.8590.16
165_V172_V0.8580.16
185_Q494_L0.8570.16
219_A464_D0.8540.16
369_L374_G0.8540.16
434_Q467_M0.8480.15
110_K511_L0.8460.15
284_A537_I0.8460.15
520_A527_V0.8450.15
235_A485_A0.8440.15
481_R508_Q0.8430.15
196_A463_L0.8420.15
362_Y365_G0.8410.15
182_I188_G0.8400.15
36_C39_L0.8390.15
49_P202_V0.8380.15
55_S59_C0.8380.15
404_E408_V0.8360.15
114_L521_E0.8360.15
230_R482_V0.8360.15
87_D198_D0.8360.15
83_Q510_V0.8360.15
8_V13_R0.8340.15
244_Y276_V0.8340.15
362_Y376_I0.8320.15
335_A338_F0.8300.15
20_N40_R0.8290.15
12_D162_L0.8280.15
153_Y157_E0.8260.15
13_R35_E0.8250.15
141_E324_L0.8200.15
402_G408_V0.8200.15
33_G37_I0.8180.15
167_D387_P0.8180.15
99_S389_G0.8170.15
295_V323_Y0.8160.15
216_M434_Q0.8140.15
439_A443_S0.8140.15
49_P58_I0.8120.15
21_Y50_D0.8120.15
171_D293_I0.8110.15
18_R173_A0.8080.15
342_A346_A0.8060.15
26_Y53_H0.8050.15
21_Y493_D0.8040.15
288_M306_V0.8040.15
435_M487_T0.8020.15
12_D31_R0.8000.15
210_L268_L0.8000.15
20_N41_G0.7990.14
130_A285_V0.7990.14
133_V289_L0.7990.14
100_L104_P0.7980.14
52_V60_L0.7970.14
323_Y445_T0.7970.14
8_V26_Y0.7970.14
330_R336_I0.7960.14
142_S549_G0.7940.14
341_H346_A0.7920.14
430_E510_V0.7920.14
175_K188_G0.7920.14
206_L485_A0.7880.14
369_L403_L0.7870.14
230_R257_Q0.7870.14
25_N29_P0.7870.14
66_I133_V0.7870.14
66_I232_A0.7860.14
323_Y396_A0.7830.14
142_S408_V0.7800.14
74_D202_V0.7790.14
358_M363_G0.7780.14
273_D512_A0.7780.14
32_T195_E0.7770.14
18_R395_F0.7760.14
55_S58_I0.7750.14
241_A244_Y0.7750.14
94_G302_V0.7740.14
301_S467_M0.7740.14
205_D267_E0.7730.14
445_T490_K0.7730.14
353_V436_R0.7720.14
33_G36_C0.7720.14
83_Q446_D0.7710.14
116_G121_G0.7680.14
112_T277_L0.7670.14
443_S447_D0.7660.14
83_Q89_P0.7660.14
337_E343_P0.7640.14
94_G264_L0.7630.14
26_Y32_T0.7610.14
366_E371_V0.7590.14
21_Y35_E0.7580.14
98_F104_P0.7570.14
32_T57_E0.7570.14
33_G55_S0.7560.14
87_D448_V0.7520.14
286_L478_E0.7520.14
306_V315_G0.7520.14
8_V24_S0.7510.14
195_E207_V0.7510.14
15_Q29_P0.7490.14
25_N39_L0.7490.14
82_P92_R0.7490.14
39_L58_I0.7490.14
397_Q402_G0.7480.14
141_E461_L0.7440.13
250_T497_L0.7440.13
30_N545_M0.7440.13
68_V83_Q0.7430.13
278_V301_S0.7430.13
368_T378_R0.7420.13
255_I522_N0.7420.13
26_Y52_V0.7410.13
49_P55_S0.7410.13
83_Q181_E0.7390.13
90_T196_A0.7370.13
115_L544_L0.7350.13
440_F443_S0.7350.13
430_E487_T0.7340.13
49_P195_E0.7340.13
79_I90_T0.7330.13
463_L514_R0.7330.13
11_L207_V0.7320.13
147_D235_A0.7290.13
340_E344_R0.7280.13
190_T194_L0.7280.13
74_D473_D0.7280.13
455_T462_Q0.7270.13
170_V549_G0.7260.13
10_D13_R0.7250.13
110_K422_I0.7240.13
114_L319_Y0.7210.13
18_R32_T0.7170.13
330_R335_A0.7160.13
503_H530_I0.7140.13
185_Q188_G0.7140.13
26_Y66_I0.7130.13
181_E192_Q0.7120.13
471_L514_R0.7070.13
8_V21_Y0.7020.13
15_Q170_V0.7020.13
403_L462_Q0.7010.13
204_D368_T0.7000.13
335_A343_P0.7000.13
388_N501_S0.6990.13
383_G538_D0.6970.13
186_F295_V0.6960.13
32_T206_L0.6960.13
17_D20_N0.6950.13
94_G502_A0.6940.13
26_Y38_T0.6940.13
213_R463_L0.6930.13
343_P346_A0.6930.13
17_D21_Y0.6900.13
363_G371_V0.6890.13
31_R263_R0.6880.13
126_V319_Y0.6860.12
250_T337_E0.6850.12
11_L549_G0.6840.12
9_V23_C0.6830.12
213_R273_D0.6810.12
431_A510_V0.6810.12
107_E112_T0.6800.12
151_D219_A0.6800.12
41_G53_H0.6800.12
84_E105_V0.6790.12
399_L403_L0.6790.12
338_F344_R0.6790.12
53_H267_E0.6780.12
105_V221_D0.6770.12
25_N210_L0.6760.12
110_K523_N0.6750.12
171_D295_V0.6750.12
21_Y38_T0.6740.12
17_D34_K0.6730.12
257_Q460_P0.6720.12
195_E216_M0.6720.12
215_V241_A0.6720.12
151_D447_D0.6710.12
185_Q236_T0.6710.12
55_S305_V0.6700.12
360_K371_V0.6700.12
550_E555_G0.6700.12
257_Q508_Q0.6690.12
111_V481_R0.6680.12
195_E263_R0.6680.12
164_A237_L0.6670.12
355_Y374_G0.6660.12
181_E237_L0.6650.12
363_G368_T0.6640.12
51_Q77_E0.6640.12
264_L419_G0.6610.12
73_F368_T0.6600.12
99_S531_D0.6590.12
122_K248_E0.6590.12
55_S65_G0.6570.12
249_L288_M0.6570.12
310_K537_I0.6570.12
273_D299_E0.6570.12
319_Y381_V0.6560.12
30_N53_H0.6550.12
31_R403_L0.6550.12
307_T508_Q0.6530.12
411_E494_L0.6520.12
13_R511_L0.6520.12
220_I443_S0.6500.12
52_V55_S0.6500.12
54_I60_L0.6490.12
330_R338_F0.6490.12
263_R375_D0.6490.12
22_E38_T0.6480.12
51_Q60_L0.6480.12
26_Y29_P0.6470.12
204_D378_R0.6470.12
399_L412_A0.6460.12
356_P361_S0.6460.12
307_T546_V0.6460.12
431_A529_V0.6450.12
389_G544_L0.6450.12
155_G159_Q0.6440.12
20_N25_N0.6430.12
22_E395_F0.6420.12
342_A351_T0.6420.12
298_G328_N0.6400.12
232_A486_A0.6400.12
40_R50_D0.6390.12
404_E517_R0.6390.12
52_V274_K0.6390.12
35_E41_G0.6360.12
21_Y73_F0.6360.12
230_R481_R0.6350.12
10_D21_Y0.6320.12
449_G458_A0.6320.12
312_V315_G0.6320.12
77_E86_D0.6310.12
197_T310_K0.6300.12
188_G324_L0.6300.12
397_Q428_Y0.6300.12
308_P494_L0.6290.12
8_V50_D0.6280.12
215_V361_S0.6260.12
68_V424_Y0.6240.11
235_A264_L0.6230.11
290_A319_Y0.6230.11
285_V306_V0.6230.11
161_Y178_Y0.6230.11
302_V547_F0.6220.11
79_I307_T0.6220.11
94_G310_K0.6220.11
11_L26_Y0.6210.11
389_G552_A0.6210.11
509_R533_D0.6200.11
68_V396_A0.6200.11
234_A243_F0.6190.11
483_A546_V0.6190.11
235_A462_Q0.6180.11
134_T149_V0.6180.11
126_V381_V0.6170.11
27_C33_G0.6170.11
28_P33_G0.6170.11
74_D86_D0.6160.11
22_E27_C0.6150.11
22_E28_P0.6150.11
358_M374_G0.6150.11
305_V526_T0.6140.11
449_G473_D0.6140.11
11_L20_N0.6130.11
210_L419_G0.6120.11
375_D549_G0.6120.11
335_A407_S0.6110.11
453_W457_I0.6110.11
83_Q442_S0.6100.11
196_A215_V0.6100.11
21_Y39_L0.6090.11
68_V441_L0.6090.11
347_S353_V0.6080.11
94_G97_S0.6060.11
101_Y261_A0.6040.11
115_L432_D0.6040.11
20_N57_E0.6030.11
361_S378_R0.6030.11
136_N328_N0.6020.11
347_S356_P0.6010.11
257_Q540_V0.6010.11
230_R307_T0.6000.11
94_G299_E0.6000.11
229_Q281_H0.5990.11
141_E169_D0.5980.11
396_A530_I0.5970.11
258_R287_D0.5960.11
13_R40_R0.5950.11
285_V522_N0.5950.11
111_V489_S0.5950.11
8_V20_N0.5950.11
107_E123_S0.5950.11
87_D234_A0.5950.11
213_R270_E0.5950.11
366_E376_I0.5950.11
199_E395_F0.5930.11
205_D493_D0.5920.11
20_N243_F0.5920.11
25_N105_V0.5920.11
531_D544_L0.5920.11
477_G480_Q0.5910.11
18_R189_N0.5900.11
270_E409_G0.5900.11
323_Y465_P0.5880.11
25_N30_N0.5880.11
164_A380_E0.5860.11
11_L77_E0.5860.11
53_H439_A0.5850.11
197_T203_L0.5850.11
361_S461_L0.5850.11
32_T439_A0.5840.11
322_G328_N0.5840.11
15_Q237_L0.5830.11
155_G161_Y0.5800.11
26_Y447_D0.5790.11
236_T449_G0.5780.11
8_V51_Q0.5770.11
276_V527_V0.5770.11
362_Y372_E0.5760.11
18_R35_E0.5740.11
446_D469_Q0.5740.11
35_E40_R0.5740.11
83_Q264_L0.5730.11
31_R162_L0.5730.11
441_L494_L0.5720.11
436_R439_A0.5720.11
142_S221_D0.5720.11
11_L264_L0.5720.11
86_D165_V0.5710.11
340_E346_A0.5700.11
20_N95_E0.5700.11
395_F399_L0.5690.11
344_R348_R0.5680.11
13_R465_P0.5680.11
89_P522_N0.5680.11
456_E489_S0.5670.11
125_A455_T0.5670.11
32_T299_E0.5670.11
21_Y40_R0.5670.11
13_R18_R0.5660.11
363_G376_I0.5660.11
496_L516_I0.5660.11
198_D324_L0.5650.11
323_Y424_Y0.5640.11
11_L53_H0.5640.11
18_R431_A0.5640.11
169_D357_D0.5640.11
77_E485_A0.5640.11
11_L361_S0.5630.11
164_A494_L0.5630.11
302_V454_Q0.5620.11
73_F186_F0.5610.11
194_L234_A0.5610.11
126_V524_E0.5590.11
308_P324_L0.5590.11
220_I436_R0.5580.11
441_L445_T0.5580.11
118_N257_Q0.5580.11
235_A446_D0.5570.10
90_T172_V0.5570.10
145_D395_F0.5560.10
203_L207_V0.5560.10
89_P445_T0.5560.10
145_D263_R0.5550.10
287_D501_S0.5540.10
318_E325_E0.5540.10
280_E502_A0.5540.10
365_G368_T0.5530.10
364_D377_N0.5520.10
369_L378_R0.5520.10
94_G235_A0.5520.10
156_T159_Q0.5510.10
260_T299_E0.5510.10
35_E466_I0.5500.10
111_V165_V0.5500.10
494_L529_V0.5500.10
11_L57_E0.5500.10
228_L297_Y0.5500.10
399_L488_L0.5490.10
105_V464_D0.5480.10
87_D485_A0.5470.10
103_L113_G0.5470.10
25_N40_R0.5470.10
30_N66_I0.5460.10
365_G376_I0.5460.10
431_A494_L0.5460.10
10_D41_G0.5450.10
531_D538_D0.5450.10
83_Q237_L0.5440.10
355_Y358_M0.5440.10
194_L203_L0.5440.10
165_V424_Y0.5440.10
115_L326_N0.5430.10
308_P448_V0.5430.10
77_E397_Q0.5430.10
145_D470_R0.5430.10
78_I495_Y0.5430.10
534_I541_S0.5420.10
344_R347_S0.5420.10
57_E465_P0.5420.10
194_L241_A0.5400.10
355_Y360_K0.5390.10
384_V534_I0.5390.10
340_E349_R0.5380.10
198_D323_Y0.5380.10
531_D535_Y0.5380.10
13_R264_L0.5380.10
243_F347_S0.5370.10
40_R53_H0.5370.10
88_Q462_Q0.5370.10
212_I218_Q0.5370.10
260_T295_V0.5360.10
535_Y544_L0.5360.10
74_D412_A0.5350.10
203_L216_M0.5330.10
93_Y297_Y0.5320.10
380_E485_A0.5310.10
226_G291_D0.5310.10
105_V299_E0.5310.10
234_A430_E0.5300.10
156_T524_E0.5300.10
66_I507_E0.5300.10
336_I344_R0.5300.10
20_N74_D0.5290.10
251_P281_H0.5290.10
52_V169_D0.5280.10
26_Y485_A0.5280.10
181_E512_A0.5280.10
32_T193_L0.5280.10
305_V460_P0.5270.10
35_E53_H0.5260.10
145_D220_I0.5260.10
13_R22_E0.5250.10
136_N317_N0.5250.10
441_L458_A0.5240.10
84_E94_G0.5240.10
451_S524_E0.5240.10
26_Y84_E0.5240.10
32_T485_A0.5230.10
79_I324_L0.5230.10
233_L447_D0.5220.10
13_R33_G0.5220.10
10_D35_E0.5220.10
358_M367_F0.5210.10
84_E97_S0.5210.10
39_L60_L0.5200.10
11_L18_R0.5170.10
110_K181_E0.5160.10
281_H480_Q0.5150.10
165_V442_S0.5140.10
24_S439_A0.5140.10
158_L483_A0.5130.10
20_N38_T0.5120.10
12_D19_C0.5110.10
12_D16_P0.5110.10
361_S490_K0.5110.10
366_E379_N0.5100.10
55_S526_T0.5090.10
12_D20_N0.5080.10
24_S36_C0.5080.10
17_D41_G0.5080.10
123_S158_L0.5070.10
21_Y24_S0.5060.10
17_D40_R0.5050.10
243_F435_M0.5050.10
37_I52_V0.5050.10
77_E449_G0.5050.10
280_E320_L0.5040.10
101_Y383_G0.5040.10
200_R467_M0.5030.10
364_D412_A0.5030.10
16_P33_G0.5020.10
14_C33_G0.5020.10
19_C33_G0.5020.10
21_Y311_S0.5020.10
186_F395_F0.5020.10
49_P184_A0.5010.10
192_Q240_D0.5010.10
237_L267_E0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3bk7A 1 0.9656 100 0.407 Contact Map
3j16B 1 0.9639 100 0.408 Contact Map
1yqtA 1 0.8377 100 0.594 Contact Map
3ozxA 1 0.8344 100 0.595 Contact Map
4f4cA 1 0.859 100 0.675 Contact Map
4q9hA 1 0.8869 100 0.677 Contact Map
4finA 2 0.759 100 0.707 Contact Map
2iw3A 2 0.777 100 0.712 Contact Map
3ux8A 2 0.7 100 0.725 Contact Map
2vf7A 2 0.7656 100 0.761 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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