Q9HMB7 - HALSA - GREMLIN Contacts

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Q9HMB7 - Probable carboxypeptidase

UniProt:	Q9HMB7	Sequences: MAHATQSPDAYDALLDHYETITGLGGAAGILSWDQEVMMPEGGTPARSTQKSAVSTVRHDLLTDQQVADWLDDLADADLTDEQAAVVREIRREHERAARVPSDLIADLSEKTSEAHPKWKQAREEDDFSIFAPVLEDLIDLKREYANHIDPDADAYEVLFADYEPYLDLDTAERVLERLRDELVPLIADIRDSDVTLADPFAGSQFDVDTQEDLARDVLDTLGYDWEHGRIDTAPHPFSSGTPFDARVTTRFDPEKPVDALLSTIHEFGHARYTLGLPRAEYGTPLGESRDLTVHESQSRLWENHIGRSPAFWEAFLPEMKTQFPQVEDATPQAAFEAANEIFEDNLIRVEADELTYHMHIVVRFEIERELIEGDLDVADVPEAWNDKYEEYLGVRPETDAEGCLQDIHWSQGSIGYFPTYSLGSVLAAQIFAALEADIGPVDERVREGDFDVVGDWLESNVHQHGARYTTPDLVREATGEAFTADYFLDHVHEKYGELYDL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	502 (487)
Sequences:	1216 (896)
Seq/√Len:	40.6

BACSU - CBP1
HALSA - Q9HMB7
SULSO - Q97UB3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
390_E	396_R	4.728	1.00
363_V	389_Y	4.065	1.00
173_E	365_F	4.039	1.00
481_E	484_T	4.022	1.00
376_L	384_A	3.895	1.00
367_I	384_A	3.463	1.00
398_E	402_E	3.458	1.00
314_E	447_R	3.427	1.00
182_E	493_H	3.308	1.00
136_E	379_A	3.102	1.00
469_Y	477_E	3.070	1.00
42_G	228_H	3.031	1.00
75_A	91_R	2.931	1.00
107_D	137_D	2.922	1.00
387_D	396_R	2.898	1.00
182_E	489_L	2.891	1.00
481_E	487_Y	2.825	1.00
85_A	88_R	2.820	1.00
132_A	379_A	2.708	1.00
132_A	378_V	2.683	1.00
222_L	268_F	2.673	1.00
383_E	387_D	2.454	1.00
80_T	83_Q	2.452	1.00
310_P	333_Q	2.434	1.00
217_D	319_E	2.429	1.00
484_T	487_Y	2.417	1.00
431_I	462_V	2.287	1.00
154_D	373_E	2.280	1.00
123_R	251_R	2.274	1.00
435_L	454_V	2.272	1.00
476_R	482_A	2.247	1.00
433_A	487_Y	2.241	1.00
426_V	483_F	2.210	1.00
224_Y	229_G	2.188	0.99
387_D	391_E	2.159	0.99
388_K	392_Y	2.128	0.99
126_D	399_T	2.109	0.99
399_T	402_E	2.103	0.99
212_E	216_R	2.098	0.99
331_T	334_A	2.087	0.99
381_V	404_C	2.085	0.99
68_A	94_H	2.073	0.99
178_R	486_D	2.069	0.99
121_Q	125_E	2.063	0.99
180_R	366_E	2.042	0.99
292_L	420_T	2.033	0.99
131_F	411_S	2.006	0.99
300_R	425_S	2.003	0.99
45_P	114_E	1.975	0.99
304_N	308_R	1.974	0.99
431_I	475_V	1.966	0.99
439_I	445_R	1.958	0.99
436_E	443_D	1.949	0.99
491_H	495_K	1.941	0.99
311_A	443_D	1.932	0.99
366_E	388_K	1.920	0.99
438_D	461_N	1.913	0.99
358_H	425_S	1.903	0.99
173_E	369_R	1.892	0.98
370_E	375_D	1.887	0.98
23_G	53_A	1.881	0.98
434_A	437_A	1.866	0.98
189_D	493_H	1.842	0.98
42_G	227_E	1.824	0.98
104_L	144_E	1.815	0.98
139_I	371_L	1.801	0.98
341_E	344_E	1.798	0.98
301_L	454_V	1.797	0.98
104_L	148_H	1.764	0.98
60_D	102_S	1.762	0.98
153_A	157_E	1.756	0.97
129_S	132_A	1.752	0.97
248_V	271_A	1.747	0.97
157_E	170_D	1.743	0.97
433_A	490_D	1.735	0.97
11_Y	86_V	1.724	0.97
19_E	49_T	1.722	0.97
433_A	481_E	1.721	0.97
91_R	95_E	1.711	0.97
431_I	478_A	1.709	0.97
219_L	268_F	1.707	0.97
27_A	31_L	1.704	0.97
215_A	264_T	1.690	0.97
137_D	140_D	1.688	0.97
15_L	83_Q	1.680	0.97
11_Y	83_Q	1.660	0.96
86_V	284_T	1.657	0.96
118_K	134_V	1.651	0.96
100_V	105_I	1.636	0.96
205_Q	254_P	1.628	0.96
171_T	472_P	1.626	0.96
20_T	61_L	1.626	0.96
125_E	130_I	1.626	0.96
21_I	61_L	1.615	0.96
218_V	261_L	1.607	0.96
462_V	474_L	1.599	0.96
441_P	444_E	1.598	0.96
143_R	377_D	1.593	0.95
263_S	350_V	1.583	0.95
239_S	246_A	1.574	0.95
301_L	435_L	1.569	0.95
317_L	332_P	1.556	0.95
12_D	16_D	1.552	0.95
278_P	464_Q	1.541	0.95
426_V	488_F	1.500	0.94
96_R	162_D	1.496	0.94
455_G	459_E	1.495	0.94
140_D	144_E	1.488	0.93
132_A	136_E	1.481	0.93
126_D	400_D	1.478	0.93
250_T	264_T	1.473	0.93
445_R	453_V	1.464	0.93
212_E	233_T	1.453	0.93
218_V	265_I	1.450	0.93
71_L	91_R	1.446	0.92
209_D	212_E	1.439	0.92
28_A	51_K	1.437	0.92
21_I	58_R	1.434	0.92
366_E	392_Y	1.429	0.92
103_D	107_D	1.421	0.92
462_V	478_A	1.415	0.92
208_V	233_T	1.412	0.92
135_L	378_V	1.392	0.91
317_L	335_A	1.385	0.91
187_I	191_R	1.379	0.91
143_R	372_I	1.379	0.91
164_E	291_D	1.377	0.91
49_T	110_E	1.375	0.90
199_D	341_E	1.371	0.90
214_L	320_M	1.368	0.90
139_I	415_I	1.368	0.90
42_G	225_D	1.364	0.90
317_L	321_K	1.360	0.90
112_T	138_L	1.360	0.90
310_P	336_F	1.359	0.90
300_R	304_N	1.346	0.89
100_V	145_Y	1.339	0.89
126_D	401_A	1.333	0.89
157_E	169_L	1.333	0.89
136_E	140_D	1.323	0.89
365_F	369_R	1.322	0.89
306_I	454_V	1.319	0.88
13_A	66_Q	1.308	0.88
469_Y	474_L	1.302	0.88
118_K	130_I	1.298	0.88
450_D	453_V	1.289	0.87
441_P	445_R	1.288	0.87
367_I	381_V	1.286	0.87
226_W	229_G	1.281	0.87
13_A	70_W	1.280	0.87
56_T	106_A	1.279	0.87
277_L	289_S	1.276	0.87
486_D	490_D	1.270	0.87
436_E	440_G	1.268	0.86
465_H	469_Y	1.268	0.86
210_T	213_D	1.261	0.86
93_E	467_A	1.261	0.86
18_Y	90_I	1.259	0.86
107_D	144_E	1.251	0.86
41_E	227_E	1.248	0.86
190_I	355_L	1.244	0.85
371_L	376_L	1.244	0.85
150_D	158_V	1.243	0.85
388_K	391_E	1.242	0.85
108_L	142_K	1.239	0.85
268_F	271_A	1.238	0.85
180_R	362_V	1.236	0.85
114_E	137_D	1.236	0.85
221_T	315_A	1.235	0.85
159_L	372_I	1.234	0.85
111_K	134_V	1.231	0.85
210_T	323_Q	1.230	0.85
127_D	130_I	1.224	0.84
335_A	342_I	1.224	0.84
290_R	471_T	1.216	0.84
432_F	436_E	1.215	0.84
221_T	316_F	1.214	0.84
442_V	454_V	1.200	0.83
17_H	70_W	1.195	0.83
390_E	397_P	1.189	0.83
220_D	226_W	1.186	0.82
178_R	485_A	1.185	0.82
377_D	380_D	1.182	0.82
217_D	323_Q	1.182	0.82
188_A	192_D	1.179	0.82
300_R	358_H	1.179	0.82
106_A	110_E	1.178	0.82
36_E	116_H	1.173	0.82
427_L	475_V	1.170	0.82
389_Y	393_L	1.168	0.81
95_E	99_R	1.162	0.81
440_G	445_R	1.159	0.81
434_A	478_A	1.158	0.81
489_L	493_H	1.157	0.81
59_H	105_I	1.153	0.81
434_A	438_D	1.142	0.80
88_R	470_T	1.141	0.80
234_A	239_S	1.138	0.80
459_E	463_H	1.127	0.79
171_T	174_R	1.127	0.79
207_D	254_P	1.121	0.79
222_L	451_F	1.113	0.78
92_R	161_A	1.111	0.78
147_N	151_P	1.111	0.78
180_R	392_Y	1.108	0.78
301_L	432_F	1.107	0.78
426_V	492_V	1.106	0.78
66_Q	69_D	1.104	0.78
206_F	324_F	1.098	0.77
128_F	400_D	1.096	0.77
228_H	244_F	1.087	0.77
147_N	155_A	1.080	0.76
41_E	121_Q	1.079	0.76
246_A	275_L	1.077	0.76
183_L	187_I	1.073	0.76
387_D	390_E	1.072	0.76
488_F	492_V	1.072	0.76
386_N	400_D	1.071	0.75
48_S	113_S	1.067	0.75
212_E	252_F	1.067	0.75
262_L	339_A	1.063	0.75
164_E	293_T	1.059	0.75
470_T	473_D	1.048	0.74
29_G	241_G	1.046	0.74
473_D	477_E	1.045	0.74
251_R	350_V	1.040	0.73
253_D	259_D	1.036	0.73
461_N	464_Q	1.036	0.73
20_T	57_V	1.036	0.73
17_H	66_Q	1.034	0.73
17_H	64_D	1.032	0.73
263_S	300_R	1.030	0.73
358_H	422_S	1.028	0.72
313_W	316_F	1.025	0.72
465_H	468_R	1.025	0.72
302_W	306_I	1.025	0.72
268_F	272_R	1.025	0.72
151_P	154_D	1.021	0.72
397_P	402_E	1.021	0.72
52_S	110_E	1.019	0.72
82_E	468_R	1.014	0.71
120_K	408_I	1.010	0.71
276_G	459_E	1.003	0.71
71_L	94_H	1.001	0.70
382_P	400_D	0.992	0.70
105_I	109_S	0.991	0.70
112_T	411_S	0.988	0.69
235_P	408_I	0.984	0.69
445_R	450_D	0.984	0.69
72_D	91_R	0.983	0.69
347_L	402_E	0.981	0.69
128_F	132_A	0.978	0.69
153_A	170_D	0.977	0.68
372_I	415_I	0.974	0.68
35_Q	44_T	0.971	0.68
108_L	145_Y	0.968	0.68
432_F	435_L	0.965	0.68
332_P	335_A	0.964	0.67
347_L	395_V	0.963	0.67
340_N	495_K	0.961	0.67
163_Y	414_S	0.960	0.67
465_H	477_E	0.960	0.67
44_T	48_S	0.955	0.67
104_L	141_L	0.953	0.67
33_W	232_D	0.952	0.66
85_A	89_E	0.951	0.66
229_G	275_L	0.951	0.66
126_D	402_E	0.950	0.66
277_L	287_G	0.948	0.66
31_L	50_Q	0.947	0.66
33_W	230_R	0.944	0.66
222_L	265_I	0.943	0.66
193_S	196_T	0.940	0.65
435_L	442_V	0.940	0.65
208_V	254_P	0.937	0.65
123_R	402_E	0.930	0.65
121_Q	130_I	0.929	0.65
185_P	189_D	0.926	0.64
321_K	328_E	0.926	0.64
222_L	302_W	0.925	0.64
71_L	90_I	0.923	0.64
384_A	388_K	0.922	0.64
182_E	186_L	0.922	0.64
138_L	415_I	0.922	0.64
94_H	98_A	0.921	0.64
386_N	396_R	0.919	0.64
371_L	404_C	0.918	0.64
325_P	328_E	0.917	0.64
145_Y	149_I	0.914	0.63
318_P	321_K	0.913	0.63
362_V	366_E	0.912	0.63
273_Y	474_L	0.907	0.63
68_A	72_D	0.906	0.63
202_A	338_A	0.904	0.62
244_F	279_R	0.904	0.62
233_T	252_F	0.903	0.62
252_F	260_A	0.899	0.62
290_R	467_A	0.896	0.62
490_D	494_E	0.895	0.62
265_I	307_G	0.895	0.62
128_F	405_L	0.894	0.62
335_A	340_N	0.886	0.61
163_Y	419_P	0.886	0.61
47_R	230_R	0.883	0.61
370_E	388_K	0.883	0.61
214_L	261_L	0.880	0.60
168_D	171_T	0.878	0.60
24_L	57_V	0.878	0.60
14_L	67_V	0.876	0.60
474_L	477_E	0.874	0.60
116_H	120_K	0.872	0.60
272_R	455_G	0.871	0.59
136_E	377_D	0.871	0.59
136_E	378_V	0.869	0.59
445_R	454_V	0.867	0.59
180_R	388_K	0.867	0.59
89_E	467_A	0.861	0.59
436_E	494_E	0.861	0.59
317_L	331_T	0.860	0.59
446_V	451_F	0.859	0.58
213_D	323_Q	0.858	0.58
59_H	97_A	0.856	0.58
163_Y	420_T	0.855	0.58
306_I	446_V	0.854	0.58
115_A	138_L	0.852	0.58
151_P	158_V	0.852	0.58
456_D	460_S	0.852	0.58
375_D	383_E	0.852	0.58
26_G	50_Q	0.850	0.58
444_E	447_R	0.847	0.57
107_D	111_K	0.843	0.57
244_F	282_Y	0.843	0.57
67_V	94_H	0.839	0.57
154_D	157_E	0.839	0.57
370_E	376_L	0.838	0.57
126_D	130_I	0.837	0.56
302_W	455_G	0.836	0.56
156_Y	419_P	0.836	0.56
472_P	482_A	0.835	0.56
257_P	320_M	0.832	0.56
198_A	334_A	0.831	0.56
487_Y	490_D	0.830	0.56
146_A	158_V	0.830	0.56
306_I	435_L	0.830	0.56
239_S	263_S	0.828	0.56
432_F	443_D	0.824	0.55
190_I	193_S	0.823	0.55
74_L	87_V	0.823	0.55
164_E	420_T	0.823	0.55
47_R	232_D	0.823	0.55
114_E	134_V	0.822	0.55
472_P	483_F	0.821	0.55
319_E	322_T	0.820	0.55
123_R	235_P	0.820	0.55
433_A	484_T	0.818	0.55
35_Q	51_K	0.817	0.55
175_V	426_V	0.811	0.54
207_D	210_T	0.811	0.54
224_Y	248_V	0.810	0.54
214_L	313_W	0.809	0.54
67_V	70_W	0.808	0.54
146_A	155_A	0.807	0.54
315_A	449_G	0.806	0.54
204_S	329_D	0.806	0.54
150_D	153_A	0.805	0.54
36_E	120_K	0.804	0.53
111_K	137_D	0.800	0.53
319_E	323_Q	0.800	0.53
216_R	226_W	0.798	0.53
11_Y	15_L	0.796	0.53
336_F	340_N	0.794	0.53
57_V	60_D	0.794	0.53
186_L	345_D	0.792	0.52
65_Q	69_D	0.791	0.52
174_R	178_R	0.788	0.52
82_E	286_L	0.784	0.52
108_L	141_L	0.783	0.51
274_T	289_S	0.779	0.51
225_D	275_L	0.775	0.51
191_R	345_D	0.775	0.51
180_R	184_V	0.775	0.51
228_H	275_L	0.772	0.50
188_A	191_R	0.772	0.50
115_A	411_S	0.772	0.50
92_R	165_P	0.768	0.50
56_T	102_S	0.767	0.50
370_E	384_A	0.764	0.50
172_A	291_D	0.764	0.50
305_H	428_A	0.763	0.50
473_D	476_R	0.759	0.49
129_S	133_P	0.758	0.49
69_D	73_D	0.756	0.49
30_I	43_G	0.756	0.49
483_F	488_F	0.755	0.49
460_S	464_Q	0.755	0.49
148_H	405_L	0.754	0.49
442_V	445_R	0.753	0.49
334_A	338_A	0.748	0.48
167_L	171_T	0.748	0.48
59_H	63_T	0.744	0.48
278_P	289_S	0.743	0.48
21_I	62_L	0.740	0.48
243_P	282_Y	0.740	0.48
334_A	342_I	0.738	0.47
122_A	405_L	0.737	0.47
217_D	322_T	0.734	0.47
44_T	117_P	0.734	0.47
347_L	389_Y	0.733	0.47
444_E	448_E	0.732	0.47
108_L	148_H	0.731	0.47
304_N	425_S	0.729	0.47
278_P	281_E	0.729	0.47
294_V	427_L	0.726	0.46
10_A	14_L	0.724	0.46
68_A	98_A	0.724	0.46
310_P	314_E	0.723	0.46
111_K	141_L	0.722	0.46
257_P	324_F	0.721	0.46
218_V	222_L	0.721	0.46
104_L	108_L	0.720	0.46
139_I	377_D	0.720	0.46
433_A	437_A	0.719	0.46
156_Y	160_F	0.719	0.46
208_V	212_E	0.718	0.45
178_R	489_L	0.717	0.45
334_A	337_E	0.715	0.45
300_R	324_F	0.713	0.45
234_A	249_T	0.712	0.45
389_Y	395_V	0.712	0.45
131_F	351_E	0.710	0.45
139_I	376_L	0.710	0.45
432_F	454_V	0.710	0.45
346_N	356_T	0.710	0.45
292_L	412_Q	0.709	0.45
231_I	264_T	0.709	0.45
186_L	492_V	0.709	0.45
152_D	157_E	0.708	0.45
142_K	372_I	0.706	0.44
29_G	240_S	0.706	0.44
259_D	350_V	0.704	0.44
224_Y	271_A	0.702	0.44
24_L	58_R	0.702	0.44
184_V	359_M	0.702	0.44
436_E	441_P	0.701	0.44
335_A	339_A	0.700	0.44
169_L	369_R	0.700	0.44
175_V	485_A	0.699	0.44
17_H	61_L	0.698	0.44
128_F	377_D	0.698	0.44
239_S	488_F	0.696	0.43
167_L	172_A	0.696	0.43
281_E	284_T	0.694	0.43
112_T	412_Q	0.693	0.43
439_I	442_V	0.693	0.43
396_R	399_T	0.691	0.43
450_D	456_D	0.690	0.43
86_V	285_P	0.690	0.43
340_N	491_H	0.689	0.43
143_R	158_V	0.689	0.43
282_Y	287_G	0.688	0.43
262_L	313_W	0.688	0.43
182_E	185_P	0.688	0.43
445_R	448_E	0.688	0.43
38_M	232_D	0.687	0.43
110_E	114_E	0.687	0.43
132_A	172_A	0.685	0.42
455_G	463_H	0.683	0.42
432_F	442_V	0.683	0.42
313_W	335_A	0.682	0.42
251_R	263_S	0.677	0.42
120_K	235_P	0.675	0.42
249_T	297_S	0.675	0.42
147_N	150_D	0.673	0.41
14_L	90_I	0.673	0.41
180_R	265_I	0.673	0.41
24_L	39_M	0.672	0.41
146_A	372_I	0.670	0.41
189_D	497_G	0.668	0.41
163_Y	361_I	0.667	0.41
453_V	456_D	0.666	0.41
32_S	36_E	0.665	0.41
104_L	111_K	0.664	0.41
115_A	412_Q	0.661	0.40
278_P	287_G	0.660	0.40
79_L	83_Q	0.659	0.40
214_L	218_V	0.659	0.40
426_V	487_Y	0.658	0.40
224_Y	361_I	0.656	0.40
11_Y	428_A	0.655	0.40
206_F	326_Q	0.654	0.40
417_Y	423_L	0.654	0.40
439_I	453_V	0.654	0.40
206_F	327_V	0.654	0.40
142_K	145_Y	0.652	0.40
274_T	295_H	0.649	0.39
122_A	128_F	0.645	0.39
112_T	115_A	0.644	0.39
226_W	275_L	0.644	0.39
179_L	426_V	0.643	0.39
355_L	488_F	0.643	0.39
32_S	240_S	0.641	0.39
324_F	425_S	0.640	0.38
336_F	342_I	0.640	0.38
214_L	256_K	0.639	0.38
444_E	494_E	0.639	0.38
334_A	341_E	0.638	0.38
30_I	241_G	0.638	0.38
175_V	483_F	0.637	0.38
441_P	450_D	0.636	0.38
32_S	116_H	0.636	0.38
263_S	425_S	0.635	0.38
102_S	106_A	0.635	0.38
180_R	264_T	0.635	0.38
163_Y	417_Y	0.634	0.38
174_R	177_E	0.634	0.38
186_L	493_H	0.634	0.38
192_D	195_V	0.633	0.38
446_V	454_V	0.632	0.38
175_V	422_S	0.632	0.38
58_R	264_T	0.631	0.38
417_Y	420_T	0.629	0.38
116_H	412_Q	0.629	0.38
363_V	393_L	0.629	0.38
48_S	114_E	0.626	0.37
313_W	332_P	0.624	0.37
301_L	420_T	0.623	0.37
330_A	334_A	0.623	0.37
273_Y	291_D	0.620	0.37
99_R	149_I	0.620	0.37
358_H	428_A	0.620	0.37
48_S	105_I	0.618	0.37
471_T	475_V	0.616	0.36
129_S	400_D	0.615	0.36
198_A	201_F	0.615	0.36
18_Y	62_L	0.615	0.36
209_D	213_D	0.614	0.36
333_Q	337_E	0.614	0.36
304_N	495_K	0.613	0.36
379_A	497_G	0.613	0.36
128_F	404_C	0.613	0.36
213_D	464_Q	0.613	0.36
456_D	459_E	0.612	0.36
76_D	177_E	0.612	0.36
231_I	263_S	0.612	0.36
149_I	158_V	0.612	0.36
13_A	17_H	0.612	0.36
354_E	495_K	0.611	0.36
25_G	58_R	0.611	0.36
321_K	437_A	0.610	0.36
200_P	334_A	0.610	0.36
116_H	408_I	0.607	0.36
48_S	132_A	0.605	0.35
139_I	378_V	0.605	0.35
92_R	110_E	0.604	0.35
313_W	320_M	0.604	0.35
367_I	370_E	0.604	0.35
27_A	54_V	0.604	0.35
105_I	141_L	0.600	0.35
270_H	295_H	0.600	0.35
176_L	422_S	0.599	0.35
104_L	145_Y	0.599	0.35
149_I	162_D	0.597	0.35
59_H	146_A	0.597	0.35
37_V	362_V	0.597	0.35
292_L	417_Y	0.596	0.35
58_R	62_L	0.595	0.35
64_D	68_A	0.595	0.35
259_D	351_E	0.594	0.35
222_L	478_A	0.594	0.35
243_P	287_G	0.594	0.35
158_V	372_I	0.594	0.35
426_V	485_A	0.590	0.34
133_P	136_E	0.589	0.34
53_A	389_Y	0.588	0.34
29_G	43_G	0.588	0.34
380_D	383_E	0.588	0.34
327_V	330_A	0.588	0.34
189_D	192_D	0.588	0.34
123_R	233_T	0.586	0.34
466_G	474_L	0.586	0.34
17_H	67_V	0.585	0.34
246_A	271_A	0.583	0.34
376_L	404_C	0.583	0.34
160_F	173_E	0.582	0.34
71_L	87_V	0.582	0.34
249_T	299_S	0.581	0.33
43_G	243_P	0.581	0.33
82_E	281_E	0.581	0.33
26_G	242_T	0.579	0.33
371_L	381_V	0.576	0.33
14_L	18_Y	0.576	0.33
375_D	387_D	0.575	0.33
142_K	162_D	0.575	0.33
448_E	452_D	0.574	0.33
22_T	25_G	0.574	0.33
270_H	424_G	0.573	0.33
219_L	248_V	0.573	0.33
109_S	149_I	0.572	0.33
374_G	422_S	0.572	0.33
311_A	447_R	0.571	0.33
33_W	229_G	0.571	0.33
186_L	489_L	0.570	0.33
39_M	47_R	0.569	0.32
286_L	468_R	0.569	0.32
451_F	454_V	0.569	0.32
43_G	277_L	0.568	0.32
34_D	247_R	0.567	0.32
62_L	90_I	0.566	0.32
150_D	155_A	0.566	0.32
313_W	317_L	0.565	0.32
305_H	425_S	0.564	0.32
51_K	98_A	0.564	0.32
108_L	111_K	0.563	0.32
316_F	320_M	0.563	0.32
18_Y	285_P	0.562	0.32
294_V	471_T	0.561	0.32
201_F	330_A	0.561	0.32
222_L	272_R	0.559	0.32
304_N	358_H	0.559	0.32
177_E	180_R	0.559	0.32
239_S	271_A	0.558	0.32
160_F	417_Y	0.558	0.32
235_P	251_R	0.557	0.32
96_R	161_A	0.556	0.31
358_H	488_F	0.555	0.31
172_A	175_V	0.555	0.31
10_A	73_D	0.554	0.31
21_I	67_V	0.553	0.31
172_A	177_E	0.553	0.31
160_F	365_F	0.552	0.31
123_R	268_F	0.550	0.31
390_E	448_E	0.550	0.31
224_Y	275_L	0.549	0.31
331_T	335_A	0.548	0.31
154_D	369_R	0.547	0.31
66_Q	70_W	0.547	0.31
14_L	74_L	0.546	0.31
131_F	163_Y	0.545	0.31
279_R	282_Y	0.544	0.30
77_A	84_A	0.543	0.30
349_R	357_Y	0.543	0.30
139_I	404_C	0.542	0.30
74_L	79_L	0.539	0.30
201_F	338_A	0.538	0.30
225_D	229_G	0.537	0.30
339_A	342_I	0.537	0.30
17_H	21_I	0.537	0.30
217_D	220_D	0.536	0.30
294_V	475_V	0.535	0.30
298_Q	458_L	0.534	0.30
436_E	461_N	0.534	0.30
92_R	140_D	0.532	0.30
302_W	446_V	0.531	0.29
144_E	460_S	0.531	0.29
367_I	371_L	0.531	0.29
219_L	397_P	0.531	0.29
306_I	452_D	0.531	0.29
123_R	215_A	0.530	0.29
408_I	411_S	0.530	0.29
122_A	134_V	0.527	0.29
18_Y	86_V	0.526	0.29
144_E	147_N	0.526	0.29
177_E	181_D	0.526	0.29
330_A	335_A	0.525	0.29
120_K	123_R	0.524	0.29
67_V	90_I	0.524	0.29
466_G	470_T	0.523	0.29
86_V	286_L	0.523	0.29
185_P	188_A	0.522	0.29
370_E	374_G	0.522	0.29
187_I	359_M	0.522	0.29
267_E	295_H	0.521	0.29
16_D	106_A	0.521	0.29
284_T	300_R	0.521	0.29
205_Q	255_E	0.521	0.29
143_R	370_E	0.520	0.29
354_E	491_H	0.520	0.29
160_F	419_P	0.519	0.29
313_W	462_V	0.519	0.29
155_A	158_V	0.518	0.29
295_H	424_G	0.517	0.28
382_P	389_Y	0.517	0.28
267_E	270_H	0.516	0.28
125_E	129_S	0.516	0.28
163_Y	292_L	0.515	0.28
164_E	427_L	0.515	0.28
189_D	383_E	0.514	0.28
442_V	446_V	0.514	0.28
166_Y	470_T	0.514	0.28
313_W	339_A	0.514	0.28
238_F	295_H	0.514	0.28
164_E	419_P	0.514	0.28
160_F	361_I	0.514	0.28
82_E	86_V	0.513	0.28
155_A	478_A	0.513	0.28
198_A	341_E	0.513	0.28
220_D	227_E	0.513	0.28
96_R	149_I	0.513	0.28
139_I	143_R	0.512	0.28
164_E	471_T	0.512	0.28
316_F	451_F	0.511	0.28
188_A	391_E	0.511	0.28
68_A	71_L	0.511	0.28
139_I	367_I	0.510	0.28
48_S	172_A	0.509	0.28
203_G	361_I	0.509	0.28
181_D	185_P	0.509	0.28
300_R	308_R	0.509	0.28
28_A	58_R	0.508	0.28
128_F	386_N	0.508	0.28
417_Y	422_S	0.508	0.28
36_E	234_A	0.507	0.28
36_E	239_S	0.506	0.28
188_A	484_T	0.506	0.28
76_D	87_V	0.506	0.28
452_D	456_D	0.505	0.28
436_E	442_V	0.505	0.28
188_A	345_D	0.504	0.27
430_Q	487_Y	0.504	0.27
436_E	439_I	0.503	0.27
116_H	134_V	0.503	0.27
216_R	220_D	0.502	0.27
309_S	446_V	0.502	0.27
187_I	342_I	0.502	0.27
65_Q	98_A	0.501	0.27
67_V	71_L	0.501	0.27
111_K	138_L	0.500	0.27
314_E	332_P	0.500	0.27
31_L	240_S	0.500	0.27
180_R	391_E	0.500	0.27

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3hoaA	2	0.9861	100	0.262	Contact Map
3dwcA	3	0.9861	100	0.273	Contact Map
3hq2A	2	0.9821	100	0.378	Contact Map
1ka2A	2	0.9821	100	0.392	Contact Map
4ca7A	1	0.9363	100	0.662	Contact Map
4ca6A	1	0.9402	100	0.671	Contact Map
4c2oA	1	0.9303	100	0.68	Contact Map
1r42A	1	0.9402	100	0.689	Contact Map
3ahnA	1	0.8924	100	0.775	Contact Map
3ce2A	1	0.8944	100	0.777	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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