Q9HMA2 - HALSA - GREMLIN Contacts

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Q9HMA2 - Excision nuclease chain A

UniProt:	Q9HMA2	Sequences: MSEEYIEVRGAEEHNLTDLDVELPRESLNVVTGLSGSGKSSLAFETIYAEGQRRYIESLSAYARNFLGQMDKPQVESVEGLSPAISIDQKNAANNPRSTVGTVTELHDYLRLLYARVGTPHCPECGREVGEQSAQQMVRRIFDLPAGTKAKLLAPVVRDQKGAFEDLFEDLVNEGYSRVAVDGESYDLAYDDPDLDENYDHTVDVVVDRVTVTEDARSRITDSVETALDEADGVLKVVVPDAGPDTELGGATARSTGDLADDAADDRLVVEFSDALACTHCGIDISEIETRSFSFNSPHGACPECEGIGNTKEVSEDLVVVDTSKPIKDVFEAWSYQRSYYRTRLDAVAAHFGVSVDTPFDELDDAVQQAFLYGTSDEVVFERSTKNGTRRKEKRFEGVIPNLERRYVETDSESTRDHIETYMSVTTCPACDGTRLKPSSRAVLVDGTPITDVNRMSIGDALAHFEGMEAELDARDTKIAAEILKEIRARLGFMTEVGLEYLTLDREASTLSGGESQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNDRLLNTLEELRDLGNTLIVVEHDEETMRRADTVIDMGPGPGRHGGEVVANGSVADVMAATDSITGDYLAGREQIPVPDERRDYDDTLTVTGARQHNLRNLDVDLPIGAFTAITGVSGSGKSTLMHDILYKGLAREMNDNTSVDPGDHDAIEGTEHVETVRLIDQSPIGRTPRSNPATYTGIFDYIREKFAQTKLATQRGYKKGRFSFNVKGGRCEACGGQGTQKIDMNFLSDVHVPCEECGGDRYNDETLDVTFKGKTIADVLDMSVEEAHDFFEADSRLGRRLQLLEDVGLDYMRLGQPSTTLSGGEAQRVKLAEELGKQSSGDTLYLLDEPTTGLHSHDERKLIEVLQRLTDRGNTVVVIEHELDLVKNADHVVDLGPEGGAAGGDVVATGTPEAVARTDDSHTGRYLRDKLPAVDREGPRSGREKPALSDD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	982 (928)
Sequences:	3346 (1542)
Seq/√Len:	50.6

ECOLI - UVRA
BACSU - UVRA
HALSA - Q9HMA2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
23_L	29_N	5.365	1.00
636_T	651_D	4.818	1.00
614_D	619_R	4.754	1.00
641_R	696_D	4.689	1.00
12_E	76_E	4.377	1.00
614_D	620_E	4.215	1.00
304_E	430_A	4.191	1.00
816_E	836_E	4.107	1.00
168_F	181_V	4.057	1.00
549_D	957_Y	3.624	1.00
292_S	440_S	3.608	1.00
9_R	22_E	3.536	1.00
5_Y	22_E	3.533	1.00
657_F	909_V	3.512	1.00
806_T	809_D	3.459	1.00
584_M	595_V	3.423	1.00
364_D	367_V	3.389	1.00
360_F	368_Q	3.385	1.00
953_H	956_R	3.382	1.00
580_T	598_N	3.338	1.00
888_H	891_R	3.323	1.00
23_L	582_I	3.319	1.00
939_A	949_T	3.288	1.00
652_L	672_M	3.248	1.00
628_R	944_E	3.203	1.00
455_R	505_D	3.123	1.00
652_L	908_V	3.094	1.00
650_V	937_V	3.073	1.00
575_M	581_V	3.072	1.00
652_L	658_T	3.053	1.00
636_T	699_E	2.958	1.00
107_H	454_N	2.932	1.00
594_E	609_D	2.908	1.00
322_D	325_K	2.906	1.00
833_Q	837_D	2.904	1.00
121_H	444_L	2.879	1.00
634_T	651_D	2.879	1.00
926_L	937_V	2.878	1.00
572_E	576_R	2.846	1.00
591_H	816_E	2.840	1.00
365_D	369_Q	2.840	1.00
939_A	946_V	2.832	1.00
659_A	920_A	2.750	1.00
21_V	582_I	2.746	1.00
600_S	603_D	2.738	1.00
119_T	476_D	2.715	1.00
685_N	688_T	2.697	1.00
127_R	280_H	2.695	1.00
473_D	476_D	2.688	1.00
546_R	929_E	2.685	1.00
7_E	22_E	2.685	1.00
328_K	357_D	2.684	1.00
8_V	21_V	2.678	1.00
808_A	812_D	2.669	1.00
324_S	361_D	2.613	1.00
29_N	564_T	2.577	1.00
875_L	908_V	2.563	1.00
154_A	231_A	2.550	1.00
684_M	687_N	2.532	1.00
460_D	932_A	2.502	1.00
180_A	204_D	2.497	1.00
590_R	844_R	2.492	1.00
549_D	573_E	2.481	1.00
224_V	235_L	2.476	1.00
637_V	652_L	2.453	1.00
597_A	604_V	2.447	1.00
820_D	823_E	2.425	1.00
581_V	604_V	2.411	1.00
689_S	692_P	2.408	1.00
122_C	125_C	2.398	1.00
581_V	601_V	2.391	1.00
47_I	566_I	2.369	1.00
349_A	354_V	2.357	1.00
805_K	813_M	2.346	1.00
631_Y	656_A	2.324	1.00
654_I	704_V	2.320	1.00
31_V	582_I	2.300	1.00
601_V	605_M	2.252	1.00
681_A	685_N	2.230	1.00
740_T	743_A	2.229	1.00
801_T	806_T	2.222	1.00
205_V	230_E	2.205	1.00
638_T	649_D	2.197	1.00
453_V	461_A	2.188	1.00
597_A	607_A	2.184	1.00
638_T	697_A	2.172	1.00
492_G	496_E	2.157	1.00
122_C	281_C	2.149	1.00
936_D	951_D	2.132	1.00
688_T	692_P	2.131	1.00
636_T	649_D	2.129	1.00
179_V	186_Y	2.123	1.00
819_H	833_Q	2.118	1.00
314_V	419_I	2.111	1.00
646_R	936_D	2.095	1.00
679_G	682_R	2.088	1.00
704_V	875_L	2.058	1.00
556_E	559_R	2.055	1.00
638_T	699_E	2.049	1.00
637_V	640_A	2.048	1.00
8_V	11_A	2.046	1.00
125_C	281_C	2.039	1.00
829_G	833_Q	2.034	1.00
737_F	810_V	2.033	1.00
682_R	688_T	2.029	1.00
682_R	685_N	2.023	1.00
549_D	553_N	2.013	1.00
620_E	891_R	2.008	1.00
660_I	672_M	1.997	1.00
685_N	692_P	1.994	1.00
813_M	821_F	1.992	1.00
354_V	367_V	1.984	1.00
124_E	281_C	1.981	1.00
453_V	465_F	1.967	1.00
152_L	237_V	1.962	0.99
812_D	844_R	1.956	0.99
145_P	148_T	1.943	0.99
317_D	323_T	1.942	0.99
681_A	684_M	1.940	0.99
434_T	451_T	1.938	0.99
171_L	205_V	1.936	0.99
613_G	617_A	1.933	0.99
805_K	821_F	1.909	0.99
141_I	224_V	1.908	0.99
123_P	285_I	1.902	0.99
430_A	438_P	1.895	0.99
922_H	945_A	1.885	0.99
642_Q	694_D	1.882	0.99
180_A	238_V	1.877	0.99
816_E	841_D	1.865	0.99
459_G	500_E	1.850	0.99
373_Y	400_I	1.845	0.99
819_H	836_E	1.843	0.99
689_S	693_G	1.839	0.99
365_D	368_Q	1.835	0.99
466_E	488_R	1.831	0.99
897_L	909_V	1.822	0.99
676_L	679_G	1.813	0.99
12_E	74_Q	1.806	0.99
641_R	694_D	1.798	0.99
196_D	199_Y	1.784	0.99
658_T	906_T	1.782	0.99
837_D	899_R	1.778	0.99
122_C	278_C	1.777	0.99
320_V	360_F	1.775	0.99
168_F	179_V	1.771	0.99
158_R	234_V	1.769	0.99
434_T	449_P	1.768	0.99
620_E	888_H	1.765	0.99
682_R	687_N	1.762	0.99
729_I	828_L	1.762	0.99
576_R	605_M	1.754	0.99
681_A	687_N	1.751	0.99
397_E	405_R	1.750	0.99
150_A	210_V	1.746	0.99
637_V	675_I	1.746	0.99
21_V	29_N	1.738	0.99
642_Q	675_I	1.735	0.99
684_M	688_T	1.726	0.99
677_Y	681_A	1.711	0.99
500_E	933_A	1.708	0.99
141_I	212_V	1.705	0.99
629_R	901_T	1.698	0.99
137_M	224_V	1.696	0.98
637_V	672_M	1.692	0.98
314_V	319_V	1.691	0.98
313_E	404_E	1.689	0.98
17_T	594_E	1.683	0.98
818_A	845_L	1.681	0.98
637_V	695_H	1.674	0.98
651_D	940_T	1.672	0.98
327_I	356_V	1.668	0.98
159_D	299_H	1.667	0.98
351_H	378_E	1.660	0.98
179_V	188_L	1.659	0.98
679_G	685_N	1.653	0.98
110_L	114_Y	1.649	0.98
891_R	895_E	1.647	0.98
687_N	692_P	1.644	0.98
764_A	787_E	1.640	0.98
119_T	128_E	1.638	0.98
448_T	456_M	1.630	0.98
603_D	607_A	1.629	0.98
650_V	924_V	1.629	0.98
597_A	603_D	1.627	0.98
153_L	206_V	1.619	0.98
330_V	360_F	1.617	0.98
358_T	362_E	1.605	0.98
690_V	693_G	1.604	0.98
705_E	871_S	1.602	0.98
117_V	472_L	1.597	0.98
730_F	807_I	1.586	0.98
348_V	354_V	1.575	0.98
176_Y	207_V	1.574	0.98
19_L	31_V	1.573	0.98
922_H	940_T	1.573	0.98
125_C	283_I	1.563	0.97
180_A	269_V	1.559	0.97
25_R	530_V	1.558	0.97
371_F	399_V	1.557	0.97
210_V	220_I	1.551	0.97
648_L	937_V	1.549	0.97
449_P	452_D	1.541	0.97
142_F	217_R	1.540	0.97
679_G	684_M	1.535	0.97
323_T	368_Q	1.533	0.97
434_T	452_D	1.531	0.97
152_L	227_A	1.531	0.97
19_L	595_V	1.526	0.97
204_D	236_K	1.519	0.97
695_H	698_I	1.505	0.97
652_L	660_I	1.503	0.97
898_Q	919_N	1.502	0.97
646_R	932_A	1.502	0.97
602_A	608_T	1.501	0.97
682_R	686_D	1.496	0.97
809_D	812_D	1.493	0.97
359_P	362_E	1.492	0.97
728_G	731_D	1.488	0.97
683_E	687_N	1.484	0.96
681_A	688_T	1.481	0.96
112_L	483_I	1.478	0.96
360_F	371_F	1.478	0.96
833_Q	836_E	1.474	0.96
576_R	601_V	1.471	0.96
19_L	584_M	1.465	0.96
675_I	679_G	1.463	0.96
29_N	582_I	1.463	0.96
125_C	278_C	1.456	0.96
573_E	576_R	1.454	0.96
383_R	388_G	1.444	0.96
530_V	535_V	1.443	0.96
738_A	750_K	1.439	0.96
815_V	843_M	1.436	0.96
238_V	269_V	1.433	0.96
141_I	237_V	1.426	0.96
463_A	467_G	1.423	0.96
462_L	495_T	1.418	0.95
403_L	419_I	1.414	0.95
549_D	956_R	1.405	0.95
642_Q	693_G	1.404	0.95
434_T	441_R	1.402	0.95
385_T	388_G	1.400	0.95
182_D	201_H	1.396	0.95
144_L	148_T	1.396	0.95
602_A	606_A	1.396	0.95
731_D	735_E	1.395	0.95
688_T	691_D	1.395	0.95
929_E	953_H	1.394	0.95
448_T	452_D	1.394	0.95
952_S	955_G	1.393	0.95
160_Q	164_F	1.389	0.95
137_M	228_L	1.387	0.95
681_A	686_D	1.382	0.95
288_I	443_V	1.381	0.95
625_P	628_R	1.380	0.95
630_D	633_D	1.372	0.95
176_Y	230_E	1.364	0.94
216_A	220_I	1.363	0.94
937_V	940_T	1.360	0.94
126_G	444_L	1.353	0.94
171_L	188_L	1.348	0.94
685_N	693_G	1.348	0.94
319_V	333_A	1.348	0.94
150_A	212_V	1.347	0.94
901_T	907_V	1.347	0.94
159_D	202_T	1.345	0.94
597_A	605_M	1.343	0.94
278_C	281_C	1.342	0.94
685_N	691_D	1.340	0.94
348_V	367_V	1.338	0.94
637_V	698_I	1.323	0.93
696_D	699_E	1.322	0.93
465_F	487_I	1.320	0.93
157_V	164_F	1.320	0.93
236_K	269_V	1.319	0.93
355_S	358_T	1.318	0.93
686_D	692_P	1.317	0.93
556_E	577_R	1.315	0.93
632_D	656_A	1.310	0.93
882_T	916_L	1.309	0.93
608_T	619_R	1.304	0.93
156_V	167_L	1.298	0.93
801_T	809_D	1.297	0.93
680_L	685_N	1.297	0.93
170_D	174_E	1.294	0.93
186_Y	193_P	1.290	0.92
730_F	793_Y	1.289	0.92
354_V	358_T	1.287	0.92
176_Y	226_T	1.280	0.92
137_M	272_F	1.274	0.92
18_D	76_E	1.270	0.92
172_V	189_A	1.269	0.92
684_M	691_D	1.257	0.91
654_I	658_T	1.252	0.91
352_F	370_A	1.249	0.91
622_I	918_K	1.246	0.91
629_R	898_Q	1.242	0.91
140_R	143_D	1.238	0.91
118_G	443_V	1.236	0.91
369_Q	373_Y	1.234	0.91
602_A	605_M	1.232	0.91
636_T	697_A	1.232	0.91
444_L	449_P	1.231	0.91
641_R	647_N	1.228	0.90
462_L	466_E	1.226	0.90
441_R	449_P	1.222	0.90
355_S	367_V	1.219	0.90
474_A	477_T	1.216	0.90
114_Y	453_V	1.213	0.90
683_E	686_D	1.212	0.90
732_Y	735_E	1.211	0.90
380_V	393_E	1.205	0.90
707_V	877_L	1.203	0.90
29_N	566_I	1.201	0.89
148_T	239_V	1.196	0.89
304_E	429_P	1.194	0.89
683_E	688_T	1.193	0.89
21_V	31_V	1.190	0.89
457_S	460_D	1.189	0.89
676_L	681_A	1.187	0.89
304_E	311_T	1.187	0.89
320_V	330_V	1.183	0.89
802_F	825_D	1.180	0.89
772_K	782_H	1.179	0.89
615_Y	620_E	1.177	0.89
349_A	356_V	1.177	0.89
680_L	701_T	1.175	0.88
169_E	172_V	1.174	0.88
642_Q	670_T	1.169	0.88
232_D	275_A	1.167	0.88
152_L	220_I	1.166	0.88
685_N	689_S	1.166	0.88
679_G	688_T	1.166	0.88
144_L	270_V	1.162	0.88
695_H	700_G	1.159	0.88
8_V	566_I	1.159	0.88
624_V	918_K	1.158	0.88
325_K	329_D	1.157	0.88
178_R	209_R	1.155	0.88
894_I	919_N	1.153	0.87
135_Q	139_R	1.153	0.87
138_V	224_V	1.152	0.87
929_E	933_A	1.152	0.87
150_A	237_V	1.149	0.87
32_T	575_M	1.149	0.87
679_G	698_I	1.148	0.87
114_Y	452_D	1.148	0.87
603_D	606_A	1.145	0.87
437_K	440_S	1.143	0.87
239_V	270_V	1.143	0.87
681_A	692_P	1.142	0.87
28_L	559_R	1.138	0.87
477_T	481_A	1.137	0.87
648_L	926_L	1.136	0.87
434_T	455_R	1.135	0.87
9_R	77_S	1.133	0.87
462_L	488_R	1.132	0.86
670_T	675_I	1.131	0.86
661_T	925_D	1.130	0.86
139_R	795_D	1.130	0.86
624_V	628_R	1.129	0.86
661_T	917_V	1.124	0.86
345_L	356_V	1.123	0.86
752_R	797_T	1.122	0.86
698_I	701_T	1.119	0.86
732_Y	827_R	1.119	0.86
362_E	366_A	1.119	0.86
383_R	387_N	1.117	0.86
320_V	368_Q	1.116	0.86
462_L	492_G	1.115	0.86
274_D	758_K	1.113	0.86
611_I	615_Y	1.112	0.85
157_V	160_Q	1.110	0.85
141_I	235_L	1.109	0.85
687_N	691_D	1.104	0.85
680_L	692_P	1.097	0.85
742_L	745_Q	1.097	0.85
358_T	367_V	1.096	0.85
468_M	472_L	1.094	0.85
328_K	356_V	1.090	0.84
134_A	224_V	1.089	0.84
791_D	812_D	1.088	0.84
321_V	332_E	1.087	0.84
114_Y	449_P	1.087	0.84
552_L	574_T	1.087	0.84
320_V	372_L	1.086	0.84
239_V	242_A	1.086	0.84
949_T	955_G	1.082	0.84
657_F	897_L	1.079	0.84
872_G	905_N	1.079	0.84
949_T	952_S	1.079	0.84
31_V	584_M	1.077	0.84
942_T	945_A	1.075	0.83
404_E	408_V	1.073	0.83
133_S	764_A	1.072	0.83
164_F	167_L	1.069	0.83
144_L	239_V	1.068	0.83
573_E	577_R	1.065	0.83
31_V	43_A	1.065	0.83
326_P	359_P	1.065	0.83
815_V	836_E	1.064	0.83
345_L	371_F	1.063	0.83
528_G	557_E	1.062	0.83
692_P	695_H	1.061	0.83
679_G	695_H	1.060	0.83
21_V	595_V	1.060	0.83
380_V	391_R	1.060	0.83
496_E	553_N	1.058	0.83
683_E	692_P	1.057	0.82
323_T	360_F	1.056	0.82
163_A	194_D	1.055	0.82
553_N	556_E	1.052	0.82
47_I	535_V	1.051	0.82
898_Q	902_D	1.050	0.82
151_K	238_V	1.048	0.82
897_L	907_V	1.048	0.82
731_D	750_K	1.048	0.82
367_V	370_A	1.045	0.82
451_T	455_R	1.043	0.82
448_T	453_V	1.040	0.81
9_R	20_D	1.039	0.81
441_R	451_T	1.039	0.81
639_G	647_N	1.038	0.81
680_L	684_M	1.036	0.81
679_G	683_E	1.036	0.81
791_D	809_D	1.036	0.81
402_N	419_I	1.035	0.81
615_Y	888_H	1.035	0.81
679_G	693_G	1.035	0.81
677_Y	707_V	1.032	0.81
28_L	565_L	1.031	0.81
4_E	26_E	1.030	0.81
604_V	613_G	1.027	0.81
460_D	463_A	1.025	0.80
597_A	600_S	1.022	0.80
631_Y	634_T	1.022	0.80
819_H	829_G	1.021	0.80
545_Q	548_N	1.021	0.80
362_E	365_D	1.016	0.80
314_V	403_L	1.013	0.80
552_L	556_E	1.012	0.80
164_F	198_N	1.010	0.79
297_S	440_S	1.009	0.79
47_I	533_L	1.009	0.79
459_G	932_A	1.008	0.79
660_I	906_T	1.007	0.79
495_T	500_E	1.005	0.79
156_V	205_V	1.003	0.79
684_M	693_G	1.001	0.79
315_S	424_S	0.999	0.79
10_G	18_D	0.997	0.79
402_N	406_R	0.995	0.78
127_R	283_I	0.992	0.78
635_L	704_V	0.990	0.78
657_F	894_I	0.989	0.78
647_N	696_D	0.988	0.78
319_V	399_V	0.988	0.78
340_Y	344_R	0.985	0.78
878_L	897_L	0.985	0.78
679_G	687_N	0.984	0.78
625_P	918_K	0.983	0.78
289_E	789_G	0.979	0.77
140_R	272_F	0.979	0.77
446_D	471_E	0.979	0.77
684_M	692_P	0.976	0.77
26_E	530_V	0.975	0.77
23_L	564_T	0.973	0.77
478_K	481_A	0.973	0.77
125_C	280_H	0.971	0.77
894_I	916_L	0.970	0.77
352_F	375_T	0.970	0.77
558_L	867_G	0.969	0.77
623_P	891_R	0.968	0.76
948_R	959_R	0.967	0.76
746_R	799_D	0.965	0.76
736_K	828_L	0.964	0.76
323_T	361_D	0.962	0.76
165_E	194_D	0.962	0.76
939_A	945_A	0.962	0.76
705_E	873_D	0.960	0.76
461_A	491_L	0.958	0.76
659_A	909_V	0.956	0.76
420_E	423_M	0.956	0.76
652_L	676_L	0.955	0.76
923_V	946_V	0.952	0.75
679_G	686_D	0.952	0.75
672_M	676_L	0.950	0.75
899_R	903_R	0.948	0.75
692_P	700_G	0.947	0.75
6_I	47_I	0.947	0.75
836_E	841_D	0.945	0.75
598_N	604_V	0.945	0.75
679_G	692_P	0.943	0.75
654_I	906_T	0.942	0.75
405_R	409_E	0.941	0.74
220_I	224_V	0.938	0.74
360_F	372_L	0.938	0.74
311_T	429_P	0.938	0.74
180_A	185_S	0.937	0.74
947_A	955_G	0.937	0.74
384_S	388_G	0.936	0.74
652_L	875_L	0.932	0.74
208_D	219_R	0.931	0.74
415_T	419_I	0.929	0.73
727_T	864_E	0.928	0.73
121_H	125_C	0.926	0.73
382_E	388_G	0.926	0.73
25_R	535_V	0.925	0.73
938_V	955_G	0.924	0.73
831_R	867_G	0.920	0.73
31_V	565_L	0.919	0.73
685_N	690_V	0.917	0.72
231_A	234_V	0.916	0.72
419_I	423_M	0.916	0.72
459_G	495_T	0.915	0.72
752_R	794_N	0.915	0.72
688_T	693_G	0.913	0.72
676_L	680_L	0.913	0.72
680_L	875_L	0.913	0.72
384_S	387_N	0.912	0.72
127_R	279_T	0.911	0.72
397_E	402_N	0.911	0.72
134_A	228_L	0.909	0.72
135_Q	221_T	0.908	0.72
328_K	346_D	0.907	0.72
197_E	200_D	0.903	0.71
682_R	692_P	0.903	0.71
162_G	201_H	0.902	0.71
124_E	283_I	0.901	0.71
351_H	379_V	0.901	0.71
363_L	368_Q	0.897	0.71
444_L	452_D	0.897	0.71
635_L	676_L	0.896	0.71
236_K	271_E	0.895	0.71
459_G	933_A	0.895	0.71
601_V	604_V	0.892	0.70
890_E	894_I	0.892	0.70
166_D	710_I	0.891	0.70
19_L	582_I	0.889	0.70
682_R	689_S	0.889	0.70
591_H	814_S	0.889	0.70
823_E	829_G	0.888	0.70
557_E	561_L	0.888	0.70
637_V	676_L	0.886	0.70
939_A	947_A	0.885	0.70
748_Y	796_E	0.884	0.70
625_P	944_E	0.882	0.70
452_D	455_R	0.882	0.70
276_L	288_I	0.881	0.69
624_V	944_E	0.880	0.69
888_H	892_K	0.880	0.69
31_V	566_I	0.880	0.69
590_R	817_E	0.876	0.69
363_L	367_V	0.876	0.69
639_G	649_D	0.875	0.69
677_Y	682_R	0.866	0.68
332_E	422_Y	0.865	0.68
281_C	284_D	0.864	0.68
748_Y	797_T	0.863	0.68
682_R	691_D	0.863	0.68
794_N	797_T	0.862	0.68
590_R	816_E	0.862	0.68
898_Q	901_T	0.862	0.68
382_E	391_R	0.862	0.68
672_M	675_I	0.862	0.68
90_K	101_G	0.861	0.68
608_T	613_G	0.859	0.67
314_V	400_I	0.859	0.67
609_D	614_D	0.858	0.67
382_E	387_N	0.856	0.67
341_Y	402_N	0.856	0.67
333_A	422_Y	0.855	0.67
924_V	937_V	0.854	0.67
639_G	695_H	0.854	0.67
103_V	508_A	0.854	0.67
303_P	437_K	0.852	0.67
8_V	47_I	0.852	0.67
656_A	922_H	0.851	0.67
463_A	466_E	0.849	0.67
94_N	508_A	0.847	0.66
360_F	363_L	0.847	0.66
546_R	953_H	0.847	0.66
686_D	689_S	0.845	0.66
239_V	243_G	0.842	0.66
759_G	763_E	0.842	0.66
936_D	940_T	0.842	0.66
174_E	230_E	0.841	0.66
458_I	495_T	0.841	0.66
603_D	608_T	0.840	0.66
731_D	740_T	0.840	0.66
358_T	364_D	0.839	0.66
945_A	948_R	0.839	0.66
917_V	923_V	0.839	0.66
152_L	235_L	0.838	0.66
171_L	174_E	0.837	0.65
677_Y	877_L	0.836	0.65
312_K	423_M	0.836	0.65
871_S	874_T	0.835	0.65
549_D	576_R	0.834	0.65
659_A	923_V	0.834	0.65
333_A	399_V	0.832	0.65
956_R	960_D	0.832	0.65
407_Y	423_M	0.831	0.65
448_T	460_D	0.830	0.65
320_V	323_T	0.829	0.65
164_F	197_E	0.828	0.65
438_P	442_A	0.827	0.65
461_A	465_F	0.825	0.64
58_S	531_G	0.824	0.64
124_E	280_H	0.823	0.64
649_D	699_E	0.822	0.64
375_T	379_V	0.822	0.64
121_H	127_R	0.822	0.64
346_D	350_A	0.821	0.64
427_T	432_D	0.818	0.64
801_T	804_G	0.817	0.64
164_F	182_D	0.817	0.64
84_A	533_L	0.814	0.63
326_P	357_D	0.814	0.63
157_V	161_K	0.813	0.63
188_L	193_P	0.812	0.63
345_L	396_F	0.811	0.63
471_E	477_T	0.810	0.63
181_V	192_D	0.810	0.63
28_L	567_V	0.808	0.63
400_I	403_L	0.807	0.63
614_D	617_A	0.807	0.63
607_A	614_D	0.805	0.62
776_N	779_S	0.804	0.62
670_T	926_L	0.803	0.62
384_S	389_T	0.801	0.62
303_P	439_S	0.801	0.62
8_V	75_V	0.798	0.62
234_V	271_E	0.797	0.62
575_M	616_L	0.797	0.62
648_L	675_I	0.796	0.62
950_D	956_R	0.796	0.62
581_V	605_M	0.794	0.61
946_V	955_G	0.792	0.61
894_I	909_V	0.792	0.61
349_A	353_G	0.790	0.61
137_M	235_L	0.790	0.61
680_L	686_D	0.790	0.61
875_L	906_T	0.789	0.61
691_D	694_D	0.789	0.61
825_D	829_G	0.789	0.61
484_L	488_R	0.789	0.61
152_L	210_V	0.788	0.61
658_T	901_T	0.786	0.61
10_G	76_E	0.785	0.60
348_V	370_A	0.785	0.60
223_S	226_T	0.785	0.60
600_S	605_M	0.783	0.60
121_H	128_E	0.783	0.60
228_L	274_D	0.782	0.60
420_E	773_I	0.781	0.60
341_Y	399_V	0.780	0.60
11_A	75_V	0.780	0.60
675_I	695_H	0.779	0.60
817_E	820_D	0.777	0.60
580_T	600_S	0.775	0.59
556_E	560_D	0.775	0.59
167_L	171_L	0.774	0.59
186_Y	192_D	0.774	0.59
13_E	71_D	0.773	0.59
687_N	693_G	0.773	0.59
503_T	906_T	0.772	0.59
313_E	426_T	0.772	0.59
319_V	400_I	0.771	0.59
330_V	345_L	0.771	0.59
735_E	750_K	0.771	0.59
417_D	420_E	0.770	0.59
375_T	395_R	0.770	0.59
833_Q	899_R	0.770	0.59
628_R	918_K	0.770	0.59
138_V	221_T	0.769	0.59
485_K	489_A	0.767	0.59
146_A	213_T	0.764	0.58
123_P	283_I	0.764	0.58
220_I	223_S	0.763	0.58
390_R	394_K	0.762	0.58
355_S	364_D	0.762	0.58
596_V	611_I	0.761	0.58
597_A	608_T	0.761	0.58
472_L	484_L	0.759	0.58
685_N	704_V	0.759	0.58
407_Y	420_E	0.757	0.58
603_D	609_D	0.756	0.58
683_E	691_D	0.756	0.58
805_K	817_E	0.756	0.58
639_G	696_D	0.754	0.57
611_I	888_H	0.753	0.57
117_V	476_D	0.753	0.57
660_I	924_V	0.753	0.57
121_H	442_A	0.752	0.57
523_T	528_G	0.751	0.57
119_T	890_E	0.751	0.57
729_I	732_Y	0.750	0.57
164_F	203_V	0.750	0.57
732_Y	831_R	0.748	0.57
864_E	867_G	0.747	0.57
406_R	409_E	0.745	0.56
682_R	693_G	0.745	0.56
809_D	938_V	0.745	0.56
865_E	876_Y	0.745	0.56
742_L	748_Y	0.744	0.56
860_V	863_A	0.743	0.56
640_A	675_I	0.743	0.56
738_A	749_K	0.742	0.56
637_V	679_G	0.742	0.56
674_D	679_G	0.741	0.56
438_P	441_R	0.741	0.56
597_A	670_T	0.741	0.56
679_G	691_D	0.741	0.56
489_A	528_G	0.740	0.56
370_A	375_T	0.739	0.56
770_T	784_P	0.738	0.56
180_A	236_K	0.737	0.56
128_E	444_L	0.734	0.55
949_T	956_R	0.734	0.55
339_S	343_T	0.733	0.55
429_P	432_D	0.732	0.55
448_T	464_H	0.732	0.55
549_D	577_R	0.731	0.55
134_A	137_M	0.730	0.55
708_R	902_D	0.730	0.55
447_G	452_D	0.729	0.55
652_L	704_V	0.728	0.55
748_Y	752_R	0.726	0.55
348_V	352_F	0.726	0.55
418_H	422_Y	0.725	0.54
605_M	608_T	0.724	0.54
350_A	353_G	0.723	0.54
614_D	888_H	0.721	0.54
121_H	438_P	0.720	0.54
124_E	127_R	0.720	0.54
632_D	654_I	0.720	0.54
642_Q	695_H	0.719	0.54
923_V	926_L	0.719	0.54
147_G	152_L	0.718	0.54
451_T	454_N	0.718	0.54
676_L	682_R	0.717	0.54
648_L	938_V	0.716	0.53
185_S	204_D	0.715	0.53
658_T	908_V	0.715	0.53
528_G	558_L	0.714	0.53
7_E	79_E	0.714	0.53
316_E	373_Y	0.713	0.53
382_E	385_T	0.712	0.53
330_V	368_Q	0.712	0.53
163_A	198_N	0.712	0.53
151_K	185_S	0.711	0.53
688_T	695_H	0.710	0.53
366_A	369_Q	0.708	0.53
850_T	876_Y	0.707	0.53
367_V	371_F	0.706	0.52
611_I	620_E	0.706	0.52
633_D	703_H	0.706	0.52
595_V	598_N	0.705	0.52
238_V	241_D	0.705	0.52
672_M	877_L	0.705	0.52
540_S	574_T	0.704	0.52
676_L	683_E	0.704	0.52
657_F	906_T	0.702	0.52
783_V	896_V	0.702	0.52
13_E	74_Q	0.702	0.52
19_L	320_V	0.702	0.52
117_V	473_D	0.702	0.52
732_Y	800_V	0.702	0.52
151_K	240_P	0.701	0.52
706_T	871_S	0.700	0.52
670_T	674_D	0.698	0.52
637_V	642_Q	0.698	0.52
819_H	837_D	0.698	0.52
676_L	908_V	0.698	0.52
326_P	329_D	0.698	0.52
334_W	345_L	0.697	0.52
635_L	652_L	0.696	0.51
41_S	673_H	0.696	0.51
764_A	771_Q	0.694	0.51
576_R	580_T	0.694	0.51
283_I	444_L	0.693	0.51
157_V	162_G	0.693	0.51
675_I	680_L	0.693	0.51
496_E	557_E	0.693	0.51
129_V	283_I	0.691	0.51
633_D	656_A	0.690	0.51
47_I	582_I	0.689	0.51
674_D	677_Y	0.688	0.51
282_G	285_I	0.688	0.51
597_A	610_S	0.687	0.51
670_T	908_V	0.686	0.50
618_G	621_Q	0.685	0.50
705_E	872_G	0.685	0.50
633_D	655_G	0.684	0.50
864_E	868_K	0.683	0.50
473_D	477_T	0.683	0.50
101_G	461_A	0.683	0.50
352_F	379_V	0.680	0.50
650_V	938_V	0.680	0.50
474_A	478_K	0.680	0.50
181_V	203_V	0.679	0.50
312_K	420_E	0.679	0.50
55_Y	315_S	0.679	0.50
161_K	201_H	0.679	0.50
167_L	205_V	0.679	0.50
742_L	746_R	0.678	0.50
686_D	693_G	0.678	0.50
446_D	452_D	0.678	0.50
622_I	625_P	0.678	0.50
211_T	222_D	0.676	0.49
348_V	379_V	0.675	0.49
955_G	958_L	0.675	0.49
631_Y	703_H	0.675	0.49
942_T	946_V	0.674	0.49
216_A	223_S	0.674	0.49
605_M	613_G	0.674	0.49
377_D	395_R	0.673	0.49
140_R	270_V	0.672	0.49
635_L	875_L	0.672	0.49
476_D	479_I	0.671	0.49
221_T	796_E	0.670	0.49
179_V	192_D	0.670	0.49
830_R	870_S	0.669	0.49
622_I	894_I	0.668	0.49
951_D	956_R	0.668	0.49
125_C	129_V	0.667	0.48
269_V	288_I	0.667	0.48
652_L	906_T	0.667	0.48
328_K	358_T	0.667	0.48
227_A	235_L	0.666	0.48
351_H	375_T	0.666	0.48
680_L	687_N	0.666	0.48
462_L	635_L	0.666	0.48
741_K	745_Q	0.666	0.48
94_N	509_S	0.665	0.48
303_P	430_A	0.665	0.48
333_A	341_Y	0.663	0.48
818_A	832_L	0.663	0.48
628_R	942_T	0.663	0.48
489_A	557_E	0.663	0.48
341_Y	344_R	0.663	0.48
622_I	919_N	0.661	0.48
546_R	550_R	0.661	0.48
147_G	211_T	0.660	0.48
195_L	201_H	0.659	0.48
686_D	691_D	0.659	0.48
91_N	887_S	0.659	0.48
552_L	595_V	0.659	0.48
120_P	443_V	0.659	0.48
31_V	189_A	0.659	0.48
318_L	321_V	0.659	0.48
887_S	894_I	0.659	0.48
158_R	202_T	0.657	0.47
306_E	334_W	0.656	0.47
553_N	557_E	0.656	0.47
819_H	823_E	0.656	0.47
508_A	516_S	0.655	0.47
346_D	356_V	0.655	0.47
412_S	416_R	0.653	0.47
870_S	903_R	0.653	0.47
630_D	634_T	0.653	0.47
746_R	796_E	0.653	0.47
125_C	135_Q	0.653	0.47
354_V	370_A	0.652	0.47
849_S	860_V	0.652	0.47
626_D	948_R	0.651	0.47
117_V	445_V	0.651	0.47
147_G	213_T	0.650	0.47
634_T	922_H	0.650	0.47
674_D	890_E	0.650	0.47
900_L	905_N	0.649	0.47
682_R	690_V	0.649	0.47
61_A	65_N	0.648	0.46
945_A	949_T	0.648	0.46
635_L	654_I	0.648	0.46
466_E	492_G	0.647	0.46
144_L	147_G	0.647	0.46
299_H	403_L	0.646	0.46
31_V	595_V	0.646	0.46
132_Q	277_A	0.644	0.46
329_D	357_D	0.644	0.46
675_I	693_G	0.644	0.46
573_E	899_R	0.644	0.46
153_L	204_D	0.643	0.46
841_D	892_K	0.643	0.46
129_V	277_A	0.643	0.46
623_P	626_D	0.642	0.46
630_D	656_A	0.641	0.46
27_S	48_Y	0.640	0.46
185_S	206_V	0.640	0.46
181_V	195_L	0.640	0.46
281_C	464_H	0.639	0.46
464_H	583_D	0.638	0.45
58_S	72_K	0.638	0.45
351_H	381_F	0.638	0.45
25_R	82_S	0.637	0.45
676_L	685_N	0.637	0.45
347_A	351_H	0.636	0.45
27_S	624_V	0.635	0.45
91_N	877_L	0.635	0.45
583_D	887_S	0.635	0.45
745_Q	800_V	0.635	0.45
887_S	905_N	0.635	0.45
12_E	18_D	0.635	0.45
810_V	813_M	0.634	0.45
933_A	936_D	0.634	0.45
434_T	793_Y	0.633	0.45
71_D	528_G	0.633	0.45
126_G	280_H	0.632	0.45
939_A	948_R	0.632	0.45
894_I	898_Q	0.632	0.45
207_V	472_L	0.631	0.45
326_P	358_T	0.631	0.45
871_S	905_N	0.631	0.45
480_A	484_L	0.631	0.45
471_E	474_A	0.631	0.45
186_Y	191_D	0.630	0.45
465_F	491_L	0.630	0.45
655_G	906_T	0.630	0.45
381_F	390_R	0.630	0.45
820_D	824_A	0.629	0.45
631_Y	902_D	0.629	0.45
693_G	700_G	0.629	0.45
732_Y	828_L	0.629	0.45
638_T	696_D	0.628	0.44
349_A	355_S	0.628	0.44
387_N	390_R	0.628	0.44
341_Y	419_I	0.627	0.44
648_L	924_V	0.626	0.44
215_D	220_I	0.626	0.44
161_K	164_F	0.625	0.44
376_S	395_R	0.624	0.44
177_S	516_S	0.624	0.44
700_G	703_H	0.624	0.44
372_L	400_I	0.623	0.44
576_R	602_A	0.623	0.44
681_A	693_G	0.622	0.44
328_K	355_S	0.622	0.44
446_D	464_H	0.621	0.44
611_I	614_D	0.620	0.44
68_G	584_M	0.618	0.43
679_G	908_V	0.618	0.43
922_H	942_T	0.618	0.43
137_M	877_L	0.618	0.43
565_L	675_I	0.617	0.43
432_D	789_G	0.616	0.43
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58_S	95_N	0.614	0.43
382_E	389_T	0.614	0.43
125_C	442_A	0.614	0.43
744_T	800_V	0.614	0.43
582_I	598_N	0.614	0.43
14_H	851_T	0.613	0.43
280_H	283_I	0.612	0.43
768_Q	771_Q	0.612	0.43
810_V	817_E	0.612	0.43
641_R	648_L	0.611	0.43
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546_R	933_A	0.611	0.43
681_A	689_S	0.610	0.43
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457_S	461_A	0.609	0.43
76_E	188_L	0.608	0.42
81_L	111_R	0.608	0.42
164_F	201_H	0.607	0.42
630_D	651_D	0.607	0.42
316_E	400_I	0.607	0.42
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742_L	800_V	0.605	0.42
950_D	959_R	0.605	0.42
683_E	689_S	0.605	0.42
217_R	221_T	0.605	0.42
321_V	330_V	0.604	0.42
918_K	958_L	0.604	0.42
225_E	752_R	0.603	0.42
670_T	704_V	0.603	0.42
676_L	695_H	0.603	0.42
740_T	802_F	0.603	0.42
292_S	437_K	0.603	0.42
683_E	695_H	0.602	0.42
127_R	281_C	0.602	0.42
418_H	421_T	0.601	0.42
366_A	950_D	0.601	0.42
229_D	274_D	0.600	0.42
446_D	468_M	0.600	0.42
748_Y	751_G	0.600	0.42
493_F	497_V	0.599	0.42
637_V	908_V	0.599	0.42
114_Y	288_I	0.599	0.42
321_V	324_S	0.599	0.42
795_D	799_D	0.599	0.42
176_Y	229_D	0.599	0.42
844_R	849_S	0.597	0.41
950_D	955_G	0.597	0.41
138_V	228_L	0.596	0.41
580_T	922_H	0.596	0.41
675_I	694_D	0.595	0.41
31_V	301_A	0.595	0.41
160_Q	198_N	0.594	0.41
651_D	699_E	0.594	0.41
306_E	418_H	0.593	0.41
169_E	173_N	0.593	0.41
575_M	601_V	0.592	0.41
697_A	700_G	0.591	0.41
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31_V	85_I	0.589	0.41
323_T	365_D	0.589	0.41
684_M	689_S	0.589	0.41
940_T	945_A	0.589	0.41
349_A	367_V	0.588	0.40
283_I	442_A	0.588	0.40
134_A	221_T	0.588	0.40
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34_L	892_K	0.587	0.40
288_I	440_S	0.586	0.40
153_L	236_K	0.585	0.40
628_R	943_P	0.585	0.40
141_I	152_L	0.585	0.40
356_V	367_V	0.584	0.40
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938_V	949_T	0.583	0.40
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816_E	820_D	0.583	0.40
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709_L	877_L	0.582	0.40
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652_L	924_V	0.581	0.40
4_E	7_E	0.581	0.40
30_V	578_A	0.581	0.40
658_T	922_H	0.580	0.40
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372_L	399_V	0.580	0.40
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523_T	922_H	0.578	0.39
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310_N	425_V	0.578	0.39
445_V	452_D	0.578	0.39
748_Y	799_D	0.578	0.39
381_F	416_R	0.577	0.39
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591_H	836_E	0.576	0.39
847_Q	851_T	0.576	0.39
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954_T	958_L	0.575	0.39
132_Q	136_Q	0.575	0.39
327_I	550_R	0.575	0.39
114_Y	231_A	0.575	0.39
318_L	642_Q	0.574	0.39
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472_L	482_E	0.574	0.39
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121_H	283_I	0.573	0.39
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740_T	837_D	0.573	0.39
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410_T	415_T	0.573	0.39
749_K	848_P	0.573	0.39
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764_A	786_E	0.559	0.38
133_S	139_R	0.559	0.38
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834_L	867_G	0.537	0.35
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363_L	370_A	0.510	0.33
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638_T	651_D	0.506	0.33
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642_Q	692_P	0.506	0.33
310_N	906_T	0.506	0.33
171_L	230_E	0.506	0.33
445_V	577_R	0.506	0.33
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581_V	598_N	0.505	0.32
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623_P	918_K	0.504	0.32
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730_F	733_I	0.504	0.32
61_A	339_S	0.504	0.32
316_E	365_D	0.504	0.32
406_R	415_T	0.504	0.32
464_H	674_D	0.504	0.32
360_F	909_V	0.503	0.32
648_L	672_M	0.503	0.32
650_V	671_L	0.503	0.32
164_F	168_F	0.503	0.32
378_E	393_E	0.503	0.32
222_D	334_W	0.503	0.32
274_D	773_I	0.503	0.32
181_V	448_T	0.503	0.32
590_R	820_D	0.503	0.32
623_P	948_R	0.502	0.32
677_Y	692_P	0.502	0.32
600_S	606_A	0.502	0.32
403_L	420_E	0.502	0.32
162_G	197_E	0.501	0.32
281_C	440_S	0.501	0.32
400_I	419_I	0.501	0.32
144_L	272_F	0.501	0.32
535_V	779_S	0.501	0.32
128_E	476_D	0.501	0.32
173_N	646_R	0.501	0.32
865_E	905_N	0.501	0.32
137_M	187_D	0.501	0.32
330_V	334_W	0.500	0.32
23_L	623_P	0.500	0.32
535_V	824_A	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2r6fA	2	0.9134	100	0.301	Contact Map
3zqjA	1	0.947	100	0.313	Contact Map
3pihA	2	0.8452	100	0.315	Contact Map
2vf7A	2	0.8075	100	0.453	Contact Map
3ux8A	2	0.5713	100	0.726	Contact Map
2iw3A	2	0.5061	100	0.889	Contact Map
4q9hA	1	0.4908	100	0.889	Contact Map
4f4cA	1	0.4715	100	0.894	Contact Map
3ozxA	1	0.4745	100	0.896	Contact Map
3bk7A	1	0.5356	100	0.896	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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