GREMLIN Database
Q9HMA2 - Excision nuclease chain A
UniProt: Q9HMA2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 982 (928)
Sequences: 3346 (1542)
Seq/√Len: 50.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
23_L29_N5.3651.00
636_T651_D4.8181.00
614_D619_R4.7541.00
641_R696_D4.6891.00
12_E76_E4.3771.00
614_D620_E4.2151.00
304_E430_A4.1911.00
816_E836_E4.1071.00
168_F181_V4.0571.00
549_D957_Y3.6241.00
292_S440_S3.6081.00
9_R22_E3.5361.00
5_Y22_E3.5331.00
657_F909_V3.5121.00
806_T809_D3.4591.00
584_M595_V3.4231.00
364_D367_V3.3891.00
360_F368_Q3.3851.00
953_H956_R3.3821.00
580_T598_N3.3381.00
888_H891_R3.3231.00
23_L582_I3.3191.00
939_A949_T3.2881.00
652_L672_M3.2481.00
628_R944_E3.2031.00
455_R505_D3.1231.00
652_L908_V3.0941.00
650_V937_V3.0731.00
575_M581_V3.0721.00
652_L658_T3.0531.00
636_T699_E2.9581.00
107_H454_N2.9321.00
594_E609_D2.9081.00
322_D325_K2.9061.00
833_Q837_D2.9041.00
121_H444_L2.8791.00
634_T651_D2.8791.00
926_L937_V2.8781.00
572_E576_R2.8461.00
591_H816_E2.8401.00
365_D369_Q2.8401.00
939_A946_V2.8321.00
659_A920_A2.7501.00
21_V582_I2.7461.00
600_S603_D2.7381.00
119_T476_D2.7151.00
685_N688_T2.6971.00
127_R280_H2.6951.00
473_D476_D2.6881.00
546_R929_E2.6851.00
7_E22_E2.6851.00
328_K357_D2.6841.00
8_V21_V2.6781.00
808_A812_D2.6691.00
324_S361_D2.6131.00
29_N564_T2.5771.00
875_L908_V2.5631.00
154_A231_A2.5501.00
684_M687_N2.5321.00
460_D932_A2.5021.00
180_A204_D2.4971.00
590_R844_R2.4921.00
549_D573_E2.4811.00
224_V235_L2.4761.00
637_V652_L2.4531.00
597_A604_V2.4471.00
820_D823_E2.4251.00
581_V604_V2.4111.00
689_S692_P2.4081.00
122_C125_C2.3981.00
581_V601_V2.3911.00
47_I566_I2.3691.00
349_A354_V2.3571.00
805_K813_M2.3461.00
631_Y656_A2.3241.00
654_I704_V2.3201.00
31_V582_I2.3001.00
601_V605_M2.2521.00
681_A685_N2.2301.00
740_T743_A2.2291.00
801_T806_T2.2221.00
205_V230_E2.2051.00
638_T649_D2.1971.00
453_V461_A2.1881.00
597_A607_A2.1841.00
638_T697_A2.1721.00
492_G496_E2.1571.00
122_C281_C2.1491.00
936_D951_D2.1321.00
688_T692_P2.1311.00
636_T649_D2.1291.00
179_V186_Y2.1231.00
819_H833_Q2.1181.00
314_V419_I2.1111.00
646_R936_D2.0951.00
679_G682_R2.0881.00
704_V875_L2.0581.00
556_E559_R2.0551.00
638_T699_E2.0491.00
637_V640_A2.0481.00
8_V11_A2.0461.00
125_C281_C2.0391.00
829_G833_Q2.0341.00
737_F810_V2.0331.00
682_R688_T2.0291.00
682_R685_N2.0231.00
549_D553_N2.0131.00
620_E891_R2.0081.00
660_I672_M1.9971.00
685_N692_P1.9941.00
813_M821_F1.9921.00
354_V367_V1.9841.00
124_E281_C1.9811.00
453_V465_F1.9671.00
152_L237_V1.9620.99
812_D844_R1.9560.99
145_P148_T1.9430.99
317_D323_T1.9420.99
681_A684_M1.9400.99
434_T451_T1.9380.99
171_L205_V1.9360.99
613_G617_A1.9330.99
805_K821_F1.9090.99
141_I224_V1.9080.99
123_P285_I1.9020.99
430_A438_P1.8950.99
922_H945_A1.8850.99
642_Q694_D1.8820.99
180_A238_V1.8770.99
816_E841_D1.8650.99
459_G500_E1.8500.99
373_Y400_I1.8450.99
819_H836_E1.8430.99
689_S693_G1.8390.99
365_D368_Q1.8350.99
466_E488_R1.8310.99
897_L909_V1.8220.99
676_L679_G1.8130.99
12_E74_Q1.8060.99
641_R694_D1.7980.99
196_D199_Y1.7840.99
658_T906_T1.7820.99
837_D899_R1.7780.99
122_C278_C1.7770.99
320_V360_F1.7750.99
168_F179_V1.7710.99
158_R234_V1.7690.99
434_T449_P1.7680.99
620_E888_H1.7650.99
682_R687_N1.7620.99
729_I828_L1.7620.99
576_R605_M1.7540.99
681_A687_N1.7510.99
397_E405_R1.7500.99
150_A210_V1.7460.99
637_V675_I1.7460.99
21_V29_N1.7380.99
642_Q675_I1.7350.99
684_M688_T1.7260.99
677_Y681_A1.7110.99
500_E933_A1.7080.99
141_I212_V1.7050.99
629_R901_T1.6980.99
137_M224_V1.6960.98
637_V672_M1.6920.98
314_V319_V1.6910.98
313_E404_E1.6890.98
17_T594_E1.6830.98
818_A845_L1.6810.98
637_V695_H1.6740.98
651_D940_T1.6720.98
327_I356_V1.6680.98
159_D299_H1.6670.98
351_H378_E1.6600.98
179_V188_L1.6590.98
679_G685_N1.6530.98
110_L114_Y1.6490.98
891_R895_E1.6470.98
687_N692_P1.6440.98
764_A787_E1.6400.98
119_T128_E1.6380.98
448_T456_M1.6300.98
603_D607_A1.6290.98
650_V924_V1.6290.98
597_A603_D1.6270.98
153_L206_V1.6190.98
330_V360_F1.6170.98
358_T362_E1.6050.98
690_V693_G1.6040.98
705_E871_S1.6020.98
117_V472_L1.5970.98
730_F807_I1.5860.98
348_V354_V1.5750.98
176_Y207_V1.5740.98
19_L31_V1.5730.98
922_H940_T1.5730.98
125_C283_I1.5630.97
180_A269_V1.5590.97
25_R530_V1.5580.97
371_F399_V1.5570.97
210_V220_I1.5510.97
648_L937_V1.5490.97
449_P452_D1.5410.97
142_F217_R1.5400.97
679_G684_M1.5350.97
323_T368_Q1.5330.97
434_T452_D1.5310.97
152_L227_A1.5310.97
19_L595_V1.5260.97
204_D236_K1.5190.97
695_H698_I1.5050.97
652_L660_I1.5030.97
898_Q919_N1.5020.97
646_R932_A1.5020.97
602_A608_T1.5010.97
682_R686_D1.4960.97
809_D812_D1.4930.97
359_P362_E1.4920.97
728_G731_D1.4880.97
683_E687_N1.4840.96
681_A688_T1.4810.96
112_L483_I1.4780.96
360_F371_F1.4780.96
833_Q836_E1.4740.96
576_R601_V1.4710.96
19_L584_M1.4650.96
675_I679_G1.4630.96
29_N582_I1.4630.96
125_C278_C1.4560.96
573_E576_R1.4540.96
383_R388_G1.4440.96
530_V535_V1.4430.96
738_A750_K1.4390.96
815_V843_M1.4360.96
238_V269_V1.4330.96
141_I237_V1.4260.96
463_A467_G1.4230.96
462_L495_T1.4180.95
403_L419_I1.4140.95
549_D956_R1.4050.95
642_Q693_G1.4040.95
434_T441_R1.4020.95
385_T388_G1.4000.95
182_D201_H1.3960.95
144_L148_T1.3960.95
602_A606_A1.3960.95
731_D735_E1.3950.95
688_T691_D1.3950.95
929_E953_H1.3940.95
448_T452_D1.3940.95
952_S955_G1.3930.95
160_Q164_F1.3890.95
137_M228_L1.3870.95
681_A686_D1.3820.95
288_I443_V1.3810.95
625_P628_R1.3800.95
630_D633_D1.3720.95
176_Y230_E1.3640.94
216_A220_I1.3630.94
937_V940_T1.3600.94
126_G444_L1.3530.94
171_L188_L1.3480.94
685_N693_G1.3480.94
319_V333_A1.3480.94
150_A212_V1.3470.94
901_T907_V1.3470.94
159_D202_T1.3450.94
597_A605_M1.3430.94
278_C281_C1.3420.94
685_N691_D1.3400.94
348_V367_V1.3380.94
637_V698_I1.3230.93
696_D699_E1.3220.93
465_F487_I1.3200.93
157_V164_F1.3200.93
236_K269_V1.3190.93
355_S358_T1.3180.93
686_D692_P1.3170.93
556_E577_R1.3150.93
632_D656_A1.3100.93
882_T916_L1.3090.93
608_T619_R1.3040.93
156_V167_L1.2980.93
801_T809_D1.2970.93
680_L685_N1.2970.93
170_D174_E1.2940.93
186_Y193_P1.2900.92
730_F793_Y1.2890.92
354_V358_T1.2870.92
176_Y226_T1.2800.92
137_M272_F1.2740.92
18_D76_E1.2700.92
172_V189_A1.2690.92
684_M691_D1.2570.91
654_I658_T1.2520.91
352_F370_A1.2490.91
622_I918_K1.2460.91
629_R898_Q1.2420.91
140_R143_D1.2380.91
118_G443_V1.2360.91
369_Q373_Y1.2340.91
602_A605_M1.2320.91
636_T697_A1.2320.91
444_L449_P1.2310.91
641_R647_N1.2280.90
462_L466_E1.2260.90
441_R449_P1.2220.90
355_S367_V1.2190.90
474_A477_T1.2160.90
114_Y453_V1.2130.90
683_E686_D1.2120.90
732_Y735_E1.2110.90
380_V393_E1.2050.90
707_V877_L1.2030.90
29_N566_I1.2010.89
148_T239_V1.1960.89
304_E429_P1.1940.89
683_E688_T1.1930.89
21_V31_V1.1900.89
457_S460_D1.1890.89
676_L681_A1.1870.89
304_E311_T1.1870.89
320_V330_V1.1830.89
802_F825_D1.1800.89
772_K782_H1.1790.89
615_Y620_E1.1770.89
349_A356_V1.1770.89
680_L701_T1.1750.88
169_E172_V1.1740.88
642_Q670_T1.1690.88
232_D275_A1.1670.88
152_L220_I1.1660.88
685_N689_S1.1660.88
679_G688_T1.1660.88
144_L270_V1.1620.88
695_H700_G1.1590.88
8_V566_I1.1590.88
624_V918_K1.1580.88
325_K329_D1.1570.88
178_R209_R1.1550.88
894_I919_N1.1530.87
135_Q139_R1.1530.87
138_V224_V1.1520.87
929_E933_A1.1520.87
150_A237_V1.1490.87
32_T575_M1.1490.87
679_G698_I1.1480.87
114_Y452_D1.1480.87
603_D606_A1.1450.87
437_K440_S1.1430.87
239_V270_V1.1430.87
681_A692_P1.1420.87
28_L559_R1.1380.87
477_T481_A1.1370.87
648_L926_L1.1360.87
434_T455_R1.1350.87
9_R77_S1.1330.87
462_L488_R1.1320.86
670_T675_I1.1310.86
661_T925_D1.1300.86
139_R795_D1.1300.86
624_V628_R1.1290.86
661_T917_V1.1240.86
345_L356_V1.1230.86
752_R797_T1.1220.86
698_I701_T1.1190.86
732_Y827_R1.1190.86
362_E366_A1.1190.86
383_R387_N1.1170.86
320_V368_Q1.1160.86
462_L492_G1.1150.86
274_D758_K1.1130.86
611_I615_Y1.1120.85
157_V160_Q1.1100.85
141_I235_L1.1090.85
687_N691_D1.1040.85
680_L692_P1.0970.85
742_L745_Q1.0970.85
358_T367_V1.0960.85
468_M472_L1.0940.85
328_K356_V1.0900.84
134_A224_V1.0890.84
791_D812_D1.0880.84
321_V332_E1.0870.84
114_Y449_P1.0870.84
552_L574_T1.0870.84
320_V372_L1.0860.84
239_V242_A1.0860.84
949_T955_G1.0820.84
657_F897_L1.0790.84
872_G905_N1.0790.84
949_T952_S1.0790.84
31_V584_M1.0770.84
942_T945_A1.0750.83
404_E408_V1.0730.83
133_S764_A1.0720.83
164_F167_L1.0690.83
144_L239_V1.0680.83
573_E577_R1.0650.83
31_V43_A1.0650.83
326_P359_P1.0650.83
815_V836_E1.0640.83
345_L371_F1.0630.83
528_G557_E1.0620.83
692_P695_H1.0610.83
679_G695_H1.0600.83
21_V595_V1.0600.83
380_V391_R1.0600.83
496_E553_N1.0580.83
683_E692_P1.0570.82
323_T360_F1.0560.82
163_A194_D1.0550.82
553_N556_E1.0520.82
47_I535_V1.0510.82
898_Q902_D1.0500.82
151_K238_V1.0480.82
897_L907_V1.0480.82
731_D750_K1.0480.82
367_V370_A1.0450.82
451_T455_R1.0430.82
448_T453_V1.0400.81
9_R20_D1.0390.81
441_R451_T1.0390.81
639_G647_N1.0380.81
680_L684_M1.0360.81
679_G683_E1.0360.81
791_D809_D1.0360.81
402_N419_I1.0350.81
615_Y888_H1.0350.81
679_G693_G1.0350.81
677_Y707_V1.0320.81
28_L565_L1.0310.81
4_E26_E1.0300.81
604_V613_G1.0270.81
460_D463_A1.0250.80
597_A600_S1.0220.80
631_Y634_T1.0220.80
819_H829_G1.0210.80
545_Q548_N1.0210.80
362_E365_D1.0160.80
314_V403_L1.0130.80
552_L556_E1.0120.80
164_F198_N1.0100.79
297_S440_S1.0090.79
47_I533_L1.0090.79
459_G932_A1.0080.79
660_I906_T1.0070.79
495_T500_E1.0050.79
156_V205_V1.0030.79
684_M693_G1.0010.79
315_S424_S0.9990.79
10_G18_D0.9970.79
402_N406_R0.9950.78
127_R283_I0.9920.78
635_L704_V0.9900.78
657_F894_I0.9890.78
647_N696_D0.9880.78
319_V399_V0.9880.78
340_Y344_R0.9850.78
878_L897_L0.9850.78
679_G687_N0.9840.78
625_P918_K0.9830.78
289_E789_G0.9790.77
140_R272_F0.9790.77
446_D471_E0.9790.77
684_M692_P0.9760.77
26_E530_V0.9750.77
23_L564_T0.9730.77
478_K481_A0.9730.77
125_C280_H0.9710.77
894_I916_L0.9700.77
352_F375_T0.9700.77
558_L867_G0.9690.77
623_P891_R0.9680.76
948_R959_R0.9670.76
746_R799_D0.9650.76
736_K828_L0.9640.76
323_T361_D0.9620.76
165_E194_D0.9620.76
939_A945_A0.9620.76
705_E873_D0.9600.76
461_A491_L0.9580.76
659_A909_V0.9560.76
420_E423_M0.9560.76
652_L676_L0.9550.76
923_V946_V0.9520.75
679_G686_D0.9520.75
672_M676_L0.9500.75
899_R903_R0.9480.75
692_P700_G0.9470.75
6_I47_I0.9470.75
836_E841_D0.9450.75
598_N604_V0.9450.75
679_G692_P0.9430.75
654_I906_T0.9420.75
405_R409_E0.9410.74
220_I224_V0.9380.74
360_F372_L0.9380.74
311_T429_P0.9380.74
180_A185_S0.9370.74
947_A955_G0.9370.74
384_S388_G0.9360.74
652_L875_L0.9320.74
208_D219_R0.9310.74
415_T419_I0.9290.73
727_T864_E0.9280.73
121_H125_C0.9260.73
382_E388_G0.9260.73
25_R535_V0.9250.73
938_V955_G0.9240.73
831_R867_G0.9200.73
31_V565_L0.9190.73
685_N690_V0.9170.72
231_A234_V0.9160.72
419_I423_M0.9160.72
459_G495_T0.9150.72
752_R794_N0.9150.72
688_T693_G0.9130.72
676_L680_L0.9130.72
680_L875_L0.9130.72
384_S387_N0.9120.72
127_R279_T0.9110.72
397_E402_N0.9110.72
134_A228_L0.9090.72
135_Q221_T0.9080.72
328_K346_D0.9070.72
197_E200_D0.9030.71
682_R692_P0.9030.71
162_G201_H0.9020.71
124_E283_I0.9010.71
351_H379_V0.9010.71
363_L368_Q0.8970.71
444_L452_D0.8970.71
635_L676_L0.8960.71
236_K271_E0.8950.71
459_G933_A0.8950.71
601_V604_V0.8920.70
890_E894_I0.8920.70
166_D710_I0.8910.70
19_L582_I0.8890.70
682_R689_S0.8890.70
591_H814_S0.8890.70
823_E829_G0.8880.70
557_E561_L0.8880.70
637_V676_L0.8860.70
939_A947_A0.8850.70
748_Y796_E0.8840.70
625_P944_E0.8820.70
452_D455_R0.8820.70
276_L288_I0.8810.69
624_V944_E0.8800.69
888_H892_K0.8800.69
31_V566_I0.8800.69
590_R817_E0.8760.69
363_L367_V0.8760.69
639_G649_D0.8750.69
677_Y682_R0.8660.68
332_E422_Y0.8650.68
281_C284_D0.8640.68
748_Y797_T0.8630.68
682_R691_D0.8630.68
794_N797_T0.8620.68
590_R816_E0.8620.68
898_Q901_T0.8620.68
382_E391_R0.8620.68
672_M675_I0.8620.68
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660_I877_L0.5500.37
674_D894_I0.5490.37
545_Q957_Y0.5490.37
770_T848_P0.5490.37
674_D909_V0.5490.37
453_V462_L0.5480.37
86_S736_K0.5480.37
587_G594_E0.5480.37
354_V558_L0.5480.37
374_G398_G0.5480.37
319_V372_L0.5480.37
637_V650_V0.5480.37
285_I440_S0.5460.36
587_G888_H0.5460.36
591_H594_E0.5460.36
289_E779_S0.5460.36
45_E52_Q0.5460.36
331_F400_I0.5450.36
401_P404_E0.5450.36
672_M908_V0.5450.36
743_A766_G0.5440.36
224_V415_T0.5440.36
575_M600_S0.5440.36
673_H709_L0.5430.36
88_D565_L0.5430.36
948_R951_D0.5430.36
916_L919_N0.5430.36
321_V331_F0.5430.36
323_T507_E0.5420.36
162_G203_V0.5420.36
946_V949_T0.5420.36
341_Y396_F0.5420.36
167_L516_S0.5420.36
550_R938_V0.5420.36
496_E554_T0.5410.36
56_I84_A0.5410.36
331_F334_W0.5410.36
600_S613_G0.5400.36
475_R773_I0.5390.36
163_A200_D0.5390.36
873_D905_N0.5390.36
223_S740_T0.5390.36
415_T418_H0.5380.36
289_E292_S0.5380.36
510_T635_L0.5380.36
924_V940_T0.5380.36
825_D905_N0.5380.36
318_L333_A0.5370.35
287_E291_R0.5370.35
127_R270_V0.5370.35
276_L285_I0.5370.35
687_N690_V0.5370.35
610_S613_G0.5370.35
271_E286_S0.5370.35
834_L867_G0.5370.35
61_A116_R0.5360.35
18_D27_S0.5360.35
447_G464_H0.5360.35
321_V333_A0.5360.35
164_F437_K0.5350.35
348_V363_L0.5350.35
482_E516_S0.5350.35
575_M597_A0.5350.35
558_L887_S0.5350.35
197_E787_E0.5350.35
639_G642_Q0.5340.35
147_G241_D0.5340.35
334_W349_A0.5340.35
162_G195_L0.5340.35
85_I730_F0.5330.35
344_R422_Y0.5330.35
328_K399_V0.5330.35
112_L289_E0.5330.35
604_V617_A0.5330.35
148_T240_P0.5330.35
8_V236_K0.5330.35
21_V609_D0.5330.35
600_S607_A0.5330.35
717_R850_T0.5330.35
8_V29_N0.5330.35
471_E626_D0.5320.35
629_R902_D0.5320.35
507_E743_A0.5320.35
375_T378_E0.5320.35
288_I292_S0.5320.35
123_P279_T0.5320.35
59_L531_G0.5320.35
657_F901_T0.5310.35
136_Q139_R0.5310.35
802_F916_L0.5310.35
545_Q673_H0.5310.35
437_K442_A0.5310.35
397_E401_P0.5300.35
210_V216_A0.5290.35
26_E535_V0.5290.35
414_S419_I0.5290.35
598_N607_A0.5290.35
161_K803_K0.5290.35
339_S814_S0.5290.35
472_L479_I0.5290.35
23_L566_I0.5290.35
397_E406_R0.5290.35
20_D638_T0.5280.35
458_I462_L0.5280.35
936_D939_A0.5280.35
322_D329_D0.5280.35
335_S390_R0.5280.35
148_T222_D0.5280.35
527_S892_K0.5280.35
463_A651_D0.5280.35
832_L845_L0.5270.35
194_D938_V0.5270.35
625_P943_P0.5270.35
614_D891_R0.5270.35
580_T596_V0.5270.35
482_E530_V0.5260.34
946_V952_S0.5260.34
19_L828_L0.5260.34
456_M460_D0.5250.34
176_Y189_A0.5250.34
635_L680_L0.5250.34
8_V485_K0.5240.34
647_N672_M0.5240.34
176_Y575_M0.5240.34
784_P789_G0.5240.34
157_V167_L0.5240.34
314_V425_V0.5230.34
634_T704_V0.5230.34
13_E533_L0.5230.34
349_A363_L0.5230.34
91_N890_E0.5230.34
412_S423_M0.5220.34
332_E890_E0.5220.34
679_G689_S0.5220.34
535_V566_I0.5220.34
657_F898_Q0.5220.34
149_K741_K0.5210.34
213_T216_A0.5200.34
565_L776_N0.5200.34
138_V516_S0.5200.34
481_A485_K0.5190.34
110_L895_E0.5190.34
604_V610_S0.5190.34
887_S916_L0.5190.34
946_V951_D0.5190.34
460_D818_A0.5190.34
558_L750_K0.5180.34
334_W894_I0.5170.34
13_E94_N0.5170.34
349_A558_L0.5170.34
402_N407_Y0.5170.34
736_K905_N0.5170.34
173_N535_V0.5160.33
93_A494_M0.5160.33
553_N606_A0.5160.33
179_V206_V0.5160.33
14_H61_A0.5150.33
59_L443_V0.5150.33
522_A866_L0.5150.33
480_A743_A0.5150.33
214_E438_P0.5150.33
57_E64_R0.5150.33
149_K211_T0.5150.33
319_V334_W0.5140.33
736_K740_T0.5140.33
358_T361_D0.5140.33
44_F540_S0.5140.33
124_E438_P0.5140.33
519_I541_I0.5140.33
129_V892_K0.5140.33
209_R219_R0.5140.33
28_L863_A0.5130.33
27_S559_R0.5130.33
810_V822_F0.5130.33
171_L179_V0.5120.33
580_T603_D0.5120.33
227_A896_V0.5110.33
327_I360_F0.5110.33
101_G458_I0.5110.33
334_W341_Y0.5110.33
172_V179_V0.5110.33
141_I210_V0.5110.33
336_Y418_H0.5100.33
348_V364_D0.5100.33
696_D700_G0.5100.33
357_D370_A0.5100.33
383_R390_R0.5100.33
446_D696_D0.5100.33
363_L370_A0.5100.33
520_R524_Q0.5090.33
394_K784_P0.5090.33
119_T279_T0.5090.33
142_F216_A0.5090.33
742_L801_T0.5090.33
475_R771_Q0.5090.33
815_V819_H0.5080.33
632_D703_H0.5080.33
202_T535_V0.5080.33
496_E550_R0.5070.33
147_G212_V0.5070.33
125_C444_L0.5070.33
117_V444_L0.5070.33
71_D782_H0.5070.33
132_Q860_V0.5070.33
291_R299_H0.5070.33
111_R479_I0.5060.33
129_V457_S0.5060.33
638_T651_D0.5060.33
322_D339_S0.5060.33
642_Q692_P0.5060.33
310_N906_T0.5060.33
171_L230_E0.5060.33
445_V577_R0.5060.33
41_S46_T0.5050.32
581_V598_N0.5050.32
352_F360_F0.5050.32
25_R28_L0.5050.32
549_D960_D0.5050.32
623_P918_K0.5040.32
180_A183_G0.5040.32
730_F733_I0.5040.32
61_A339_S0.5040.32
316_E365_D0.5040.32
406_R415_T0.5040.32
464_H674_D0.5040.32
360_F909_V0.5030.32
648_L672_M0.5030.32
650_V671_L0.5030.32
164_F168_F0.5030.32
378_E393_E0.5030.32
222_D334_W0.5030.32
274_D773_I0.5030.32
181_V448_T0.5030.32
590_R820_D0.5030.32
623_P948_R0.5020.32
677_Y692_P0.5020.32
600_S606_A0.5020.32
403_L420_E0.5020.32
162_G197_E0.5010.32
281_C440_S0.5010.32
400_I419_I0.5010.32
144_L272_F0.5010.32
535_V779_S0.5010.32
128_E476_D0.5010.32
173_N646_R0.5010.32
865_E905_N0.5010.32
137_M187_D0.5010.32
330_V334_W0.5000.32
23_L623_P0.5000.32
535_V824_A0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2r6fA 2 0.9134 100 0.301 Contact Map
3zqjA 1 0.947 100 0.313 Contact Map
3pihA 2 0.8452 100 0.315 Contact Map
2vf7A 2 0.8075 100 0.453 Contact Map
3ux8A 2 0.5713 100 0.726 Contact Map
2iw3A 2 0.5061 100 0.889 Contact Map
4q9hA 1 0.4908 100 0.889 Contact Map
4f4cA 1 0.4715 100 0.894 Contact Map
3ozxA 1 0.4745 100 0.896 Contact Map
3bk7A 1 0.5356 100 0.896 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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