EF2 - HALSA - GREMLIN Contacts

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EF2 - Elongation factor 2

UniProt:	Q9HM85	Sequences: MGRRKKIVEQCERLMDNPEQIRNIAIAAHVDHGKTTLTDNLLAGAGMISEDTAGQQLAMDTEEDEQERGITIDAANVSMTHEYEGDDHLINLIDTPGHVDFGGDVTRAMRAVDGALVVVDAVEGAMPQTETVVRQALREGVKPTLFINKVDRLISELQEGPEEMQERLLSVIGDVNELIRGMTEEKDDIEDWTVSVEDGTVAFGSALYKWGVSMPSMQRTGMDFGDIIDLERSDKREELHEQTPLADVVLDMVAEHFPNPIDAQPRRIPTVWRGDADSEIAESMRLVDEDGEVVLMVTDIGVDPHAGEIAAGRVFSGTLEKGQELYVSGTAGKNRVQSVGIYMGGEREEVDEVPAGNIAAVTGLKDAIAGSTVSNEEMTPFESIDHISEPVITKSIEAQNMDDLPKLIETLRQVSKEDPTISIEINEDTGEHLISGQGELHLEVQTQRIERNQGIPVTTGEPIVVYRETPTSDSQEVEGVSPNRHNKFYITVEQLSDDVLEEIRLGEVSMDMPEQERREVLQEAGMDKETSQDVENIIGRNIFIDDTKGIQHLNETMELVVDGLTDSLEDGPLAAEPVEGALIRLHDARLHEDAIHRGPAQVIPATRDAVHRALIDADIRLLEPIQDVRIDVPSEHMGAASGEVQGRRGRVDDMYQEGDLMVVEGIAPVDEMIGFSSDIRSATEGRASWNTENAGFRVMADNLQREIIMEIRERKGMKTELPESITHF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	728 (686)
Sequences:	1374 (824)
Seq/√Len:	31.5

ECOLI - EFG LEPA TYPA RF3
BACSU - EFG LEPA TYPA
HALSA - EF2
SULSO - EF2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
353_V	359_A	6.866	1.00
121_A	147_I	6.241	1.00
320_E	352_E	5.555	1.00
319_L	361_V	4.448	1.00
450_E	456_P	4.052	1.00
439_E	674_G	3.971	1.00
28_A	31_D	3.949	1.00
132_V	135_Q	3.793	1.00
583_I	610_V	3.755	1.00
447_Q	451_R	3.739	1.00
42_L	77_V	3.588	1.00
25_A	112_V	3.479	1.00
353_V	357_N	3.450	1.00
421_I	445_Q	3.389	1.00
283_S	292_E	3.325	1.00
24_I	253_V	3.287	1.00
295_L	319_L	3.136	1.00
366_D	369_A	3.116	1.00
61_T	75_A	3.111	1.00
626_Q	669_V	2.995	1.00
491_T	586_H	2.981	1.00
630_I	640_A	2.971	1.00
146_F	204_G	2.944	1.00
367_A	371_S	2.884	1.00
63_E	67_E	2.849	1.00
119_V	145_L	2.801	1.00
319_L	336_V	2.581	1.00
29_H	32_H	2.561	1.00
276_A	281_A	2.534	1.00
410_T	449_I	2.525	1.00
606_T	610_V	2.519	1.00
466_Y	670_D	2.505	1.00
667_A	675_F	2.503	0.99
152_R	156_E	2.500	0.99
38_T	59_M	2.471	0.99
517_R	521_L	2.459	0.99
293_V	325_L	2.450	0.99
37_L	249_V	2.443	0.99
615_I	619_I	2.420	0.99
392_I	673_I	2.403	0.99
109_M	115_A	2.379	0.99
297_V	310_A	2.378	0.99
469_T	620_R	2.376	0.99
644_V	649_G	2.375	0.99
27_A	115_A	2.274	0.99
578_V	614_L	2.256	0.99
535_E	539_G	2.250	0.99
502_E	524_A	2.236	0.99
627_D	664_E	2.221	0.99
623_E	648_R	2.202	0.99
283_S	291_G	2.192	0.99
609_A	613_A	2.183	0.99
403_D	406_K	2.165	0.99
446_T	450_E	2.157	0.98
76_N	358_I	2.155	0.98
339_V	361_V	2.137	0.98
497_D	501_E	2.131	0.98
194_V	200_T	2.093	0.98
305_H	309_I	2.070	0.98
543_F	585_L	2.066	0.98
252_M	256_H	2.063	0.98
612_R	616_D	2.050	0.98
519_E	522_Q	2.044	0.98
295_L	314_V	2.040	0.98
643_E	675_F	2.031	0.98
305_H	308_E	2.031	0.98
518_R	521_L	2.028	0.98
647_R	674_G	1.996	0.97
203_F	212_V	1.994	0.97
680_R	685_G	1.984	0.97
196_V	201_V	1.979	0.97
646_G	678_D	1.955	0.97
189_I	192_W	1.953	0.97
288_D	291_G	1.934	0.97
23_N	26_I	1.933	0.97
294_V	374_S	1.932	0.97
288_D	292_E	1.924	0.97
105_V	132_V	1.901	0.97
196_V	200_T	1.899	0.97
560_V	606_T	1.879	0.96
501_E	505_L	1.879	0.96
31_D	71_T	1.878	0.96
104_D	299_D	1.877	0.96
119_V	129_T	1.872	0.96
354_P	396_I	1.869	0.96
110_R	135_Q	1.868	0.96
393_T	433_L	1.866	0.96
620_R	703_L	1.842	0.96
217_M	221_G	1.835	0.96
28_A	38_T	1.815	0.95
17_N	20_Q	1.807	0.95
125_A	129_T	1.800	0.95
263_A	294_V	1.795	0.95
480_V	591_H	1.792	0.95
350_V	353_V	1.792	0.95
566_D	603_I	1.786	0.95
341_I	350_V	1.778	0.95
60_D	65_E	1.773	0.95
687_A	693_N	1.768	0.95
27_A	136_A	1.767	0.95
309_I	360_A	1.761	0.95
250_L	253_V	1.759	0.95
132_V	136_A	1.746	0.94
579_E	696_F	1.744	0.94
492_V	583_I	1.737	0.94
62_E	66_Q	1.735	0.94
144_T	252_M	1.732	0.94
31_D	70_I	1.722	0.94
439_E	647_R	1.704	0.94
490_I	609_A	1.690	0.93
705_R	709_M	1.683	0.93
26_I	32_H	1.671	0.93
667_A	672_M	1.661	0.93
121_A	168_L	1.654	0.93
321_K	351_D	1.650	0.93
22_R	260_P	1.646	0.92
572_P	614_L	1.637	0.92
72_I	444_V	1.634	0.92
81_H	251_D	1.633	0.92
114_G	257_F	1.624	0.92
116_L	253_V	1.615	0.92
196_V	203_F	1.611	0.92
98_H	438_G	1.610	0.92
160_G	163_E	1.594	0.91
111_A	298_T	1.592	0.91
28_A	71_T	1.590	0.91
26_I	118_V	1.568	0.90
90_I	585_L	1.567	0.90
147_I	171_V	1.562	0.90
381_F	384_I	1.559	0.90
399_Q	456_P	1.558	0.90
563_G	610_V	1.557	0.90
364_L	373_V	1.554	0.90
314_V	359_A	1.551	0.90
130_E	136_A	1.550	0.90
482_P	605_A	1.549	0.90
297_V	336_V	1.545	0.90
560_V	563_G	1.544	0.90
603_I	607_R	1.541	0.90
145_L	194_V	1.540	0.90
325_L	373_V	1.539	0.90
282_E	286_L	1.530	0.89
37_L	118_V	1.524	0.89
295_L	361_V	1.512	0.89
666_I	697_R	1.497	0.88
65_E	68_R	1.493	0.88
110_R	139_E	1.486	0.88
75_A	344_G	1.486	0.88
647_R	668_P	1.486	0.88
196_V	212_V	1.481	0.88
608_D	611_H	1.478	0.88
102_G	128_Q	1.477	0.88
627_D	692_E	1.470	0.87
29_H	75_A	1.470	0.87
59_M	71_T	1.466	0.87
320_E	323_Q	1.463	0.87
293_V	318_T	1.463	0.87
534_V	542_I	1.463	0.87
325_L	346_E	1.461	0.87
493_E	584_R	1.456	0.87
277_D	281_A	1.455	0.87
201_V	212_V	1.445	0.86
122_V	152_R	1.432	0.86
202_A	252_M	1.405	0.85
41_L	176_N	1.404	0.85
338_S	362_T	1.404	0.85
189_I	193_T	1.401	0.85
248_V	252_M	1.400	0.85
394_K	446_T	1.399	0.85
22_R	29_H	1.391	0.84
338_S	349_E	1.390	0.84
336_V	371_S	1.389	0.84
495_L	499_V	1.387	0.84
364_L	367_A	1.387	0.84
230_L	238_E	1.386	0.84
25_A	28_A	1.385	0.84
94_D	97_G	1.374	0.83
500_L	540_R	1.373	0.83
53_A	57_L	1.370	0.83
527_D	532_Q	1.363	0.83
230_L	235_K	1.362	0.83
292_E	316_S	1.356	0.83
418_D	441_H	1.356	0.83
220_T	224_F	1.352	0.82
117_V	129_T	1.352	0.82
297_V	522_Q	1.348	0.82
490_I	606_T	1.344	0.82
281_A	284_M	1.343	0.82
400_N	403_D	1.339	0.82
195_S	198_D	1.338	0.82
21_I	91_N	1.338	0.82
628_V	675_F	1.334	0.82
312_G	361_V	1.334	0.82
57_L	60_D	1.326	0.81
150_V	210_W	1.325	0.81
24_I	90_I	1.323	0.81
397_E	458_T	1.322	0.81
403_D	455_I	1.322	0.81
30_V	71_T	1.318	0.81
520_V	523_E	1.314	0.81
218_Q	221_G	1.314	0.81
281_A	285_R	1.313	0.80
276_A	285_R	1.309	0.80
77_V	343_M	1.304	0.80
128_Q	131_T	1.302	0.80
563_G	567_S	1.299	0.80
128_Q	135_Q	1.299	0.80
27_A	117_V	1.294	0.79
669_V	672_M	1.290	0.79
38_T	92_L	1.285	0.79
482_P	598_G	1.284	0.79
488_F	609_A	1.282	0.79
196_V	217_M	1.276	0.79
159_E	401_M	1.275	0.78
282_E	285_R	1.274	0.78
98_H	120_D	1.272	0.78
57_L	66_Q	1.269	0.78
71_T	77_V	1.267	0.78
102_G	106_T	1.257	0.77
473_D	493_E	1.255	0.77
480_V	487_K	1.254	0.77
507_E	523_E	1.254	0.77
190_E	232_R	1.253	0.77
24_I	453_Q	1.251	0.77
221_G	224_F	1.249	0.77
578_V	588_A	1.247	0.77
62_E	73_D	1.237	0.76
327_V	371_S	1.226	0.76
630_I	644_V	1.224	0.76
28_A	33_G	1.218	0.75
318_T	495_L	1.211	0.75
118_V	319_L	1.209	0.75
250_L	257_F	1.201	0.74
176_N	205_S	1.201	0.74
23_N	28_A	1.200	0.74
634_S	637_M	1.197	0.74
253_V	260_P	1.193	0.74
259_N	262_D	1.193	0.74
425_I	621_L	1.188	0.73
397_E	430_G	1.187	0.73
250_L	260_P	1.186	0.73
70_I	98_H	1.183	0.73
71_T	128_Q	1.182	0.73
414_V	421_I	1.179	0.73
147_I	227_I	1.175	0.72
278_S	283_S	1.174	0.72
521_L	525_G	1.171	0.72
22_R	114_G	1.169	0.72
379_T	382_E	1.167	0.72
31_D	34_K	1.165	0.72
92_L	108_A	1.162	0.72
394_K	460_G	1.157	0.71
60_D	68_R	1.149	0.71
628_V	691_T	1.147	0.71
318_T	352_E	1.146	0.71
679_I	695_G	1.145	0.70
39_D	57_L	1.145	0.70
52_T	55_Q	1.144	0.70
81_H	85_G	1.143	0.70
518_R	531_S	1.139	0.70
82_E	87_D	1.135	0.70
115_A	649_G	1.126	0.69
99_V	131_T	1.121	0.69
431_E	454_G	1.119	0.69
557_M	585_L	1.114	0.68
627_D	694_A	1.114	0.68
27_A	109_M	1.112	0.68
90_I	357_N	1.106	0.68
60_D	69_G	1.101	0.67
469_T	622_L	1.099	0.67
203_F	206_A	1.091	0.67
102_G	135_Q	1.090	0.67
32_H	39_D	1.088	0.66
414_V	449_I	1.086	0.66
144_T	257_F	1.085	0.66
249_V	257_F	1.085	0.66
221_G	396_I	1.083	0.66
559_L	599_P	1.079	0.66
314_V	353_V	1.077	0.66
60_D	70_I	1.075	0.66
295_L	359_A	1.075	0.66
128_Q	132_V	1.075	0.66
449_I	453_Q	1.069	0.65
27_A	36_T	1.069	0.65
450_E	453_Q	1.067	0.65
64_D	447_Q	1.065	0.65
291_G	316_S	1.063	0.65
28_A	32_H	1.062	0.65
517_R	522_Q	1.059	0.64
278_S	284_M	1.054	0.64
117_V	132_V	1.053	0.64
518_R	528_K	1.052	0.64
111_A	141_V	1.051	0.64
200_T	203_F	1.051	0.64
251_D	255_E	1.050	0.64
496_S	526_M	1.048	0.64
528_K	531_S	1.047	0.63
295_L	312_G	1.044	0.63
57_L	68_R	1.043	0.63
89_L	357_N	1.042	0.63
497_D	505_L	1.041	0.63
448_R	452_N	1.041	0.63
53_A	66_Q	1.040	0.63
82_E	85_G	1.038	0.63
74_A	417_E	1.036	0.63
412_R	469_T	1.031	0.62
693_N	696_F	1.029	0.62
68_R	397_E	1.026	0.62
247_D	260_P	1.025	0.62
321_K	349_E	1.025	0.62
65_E	69_G	1.025	0.62
250_L	258_P	1.024	0.62
674_G	678_D	1.023	0.62
129_T	145_L	1.022	0.62
32_H	119_V	1.022	0.62
106_T	135_Q	1.020	0.61
201_V	205_S	1.019	0.61
421_I	434_I	1.018	0.61
219_R	223_D	1.016	0.61
483_N	486_N	1.014	0.61
24_I	466_Y	1.013	0.61
23_N	91_N	1.012	0.61
549_G	591_H	1.009	0.61
88_H	254_A	1.008	0.60
234_D	238_E	1.006	0.60
203_F	210_W	1.004	0.60
554_N	667_A	1.003	0.60
250_L	435_S	1.001	0.60
28_A	34_K	0.999	0.60
500_L	580_G	0.999	0.60
222_M	254_A	0.998	0.60
258_P	263_A	0.994	0.59
679_I	685_G	0.990	0.59
632_V	636_H	0.988	0.59
268_I	276_A	0.987	0.59
68_R	98_H	0.984	0.59
80_T	150_V	0.984	0.59
527_D	531_S	0.983	0.58
60_D	66_Q	0.982	0.58
55_Q	66_Q	0.981	0.58
595_I	602_V	0.979	0.58
25_A	109_M	0.975	0.58
512_M	519_E	0.973	0.58
439_E	673_I	0.973	0.58
49_S	54_G	0.972	0.58
114_G	132_V	0.970	0.57
196_V	199_G	0.968	0.57
236_R	270_T	0.968	0.57
116_L	207_L	0.968	0.57
74_A	93_I	0.965	0.57
361_V	585_L	0.963	0.57
508_V	520_V	0.962	0.57
640_A	681_S	0.959	0.57
147_I	563_G	0.957	0.56
206_A	210_W	0.956	0.56
617_A	623_E	0.955	0.56
133_V	143_P	0.954	0.56
150_V	663_V	0.954	0.56
68_R	101_F	0.953	0.56
45_A	78_S	0.952	0.56
37_L	209_K	0.952	0.56
25_A	31_D	0.950	0.56
128_Q	418_D	0.949	0.56
319_L	578_V	0.948	0.56
33_G	36_T	0.946	0.56
61_T	64_D	0.946	0.56
384_I	621_L	0.946	0.56
434_I	445_Q	0.943	0.55
597_R	604_P	0.942	0.55
102_G	108_A	0.938	0.55
44_G	247_D	0.938	0.55
339_V	442_L	0.929	0.54
535_E	540_R	0.929	0.54
105_V	149_K	0.928	0.54
434_I	454_G	0.928	0.54
257_F	674_G	0.927	0.54
67_E	594_A	0.924	0.54
268_I	281_A	0.921	0.54
116_L	249_V	0.920	0.53
398_A	577_P	0.920	0.53
340_G	362_T	0.920	0.53
519_E	525_G	0.918	0.53
530_T	533_D	0.917	0.53
98_H	104_D	0.917	0.53
205_S	456_P	0.917	0.53
329_G	332_G	0.916	0.53
73_D	679_I	0.915	0.53
280_I	283_S	0.915	0.53
286_L	289_E	0.915	0.53
212_V	221_G	0.910	0.53
62_E	673_I	0.909	0.53
597_R	601_Q	0.908	0.52
251_D	257_F	0.908	0.52
26_I	116_L	0.907	0.52
231_E	255_E	0.907	0.52
91_N	102_G	0.902	0.52
260_P	313_R	0.901	0.52
37_L	40_N	0.899	0.52
546_D	584_R	0.898	0.52
247_D	254_A	0.898	0.52
493_E	582_L	0.898	0.52
136_A	143_P	0.896	0.52
399_Q	458_T	0.895	0.51
280_I	285_R	0.895	0.51
319_L	325_L	0.894	0.51
46_G	71_T	0.893	0.51
64_D	72_I	0.892	0.51
405_P	604_P	0.892	0.51
484_R	488_F	0.892	0.51
69_G	440_L	0.889	0.51
132_V	257_F	0.888	0.51
206_A	214_M	0.888	0.51
310_A	339_V	0.887	0.51
48_I	343_M	0.886	0.51
476_E	479_G	0.885	0.51
26_I	38_T	0.883	0.50
98_H	149_K	0.881	0.50
93_I	112_V	0.880	0.50
260_P	264_Q	0.880	0.50
619_I	629_R	0.880	0.50
25_A	107_R	0.878	0.50
277_D	287_V	0.878	0.50
205_S	430_G	0.878	0.50
590_L	594_A	0.877	0.50
620_R	702_N	0.874	0.50
585_L	602_V	0.873	0.50
129_T	419_P	0.870	0.49
327_V	369_A	0.870	0.49
61_T	66_Q	0.870	0.49
523_E	530_T	0.869	0.49
60_D	101_F	0.867	0.49
235_K	238_E	0.867	0.49
63_E	99_V	0.865	0.49
553_L	557_M	0.863	0.49
274_G	598_G	0.857	0.48
605_A	609_A	0.856	0.48
260_P	263_A	0.856	0.48
75_A	122_V	0.854	0.48
291_G	318_T	0.852	0.48
247_D	314_V	0.852	0.48
65_E	101_F	0.850	0.48
473_D	491_T	0.848	0.48
314_V	354_P	0.846	0.47
319_L	323_Q	0.845	0.47
696_F	703_L	0.845	0.47
17_N	21_I	0.843	0.47
36_T	93_I	0.842	0.47
263_A	267_R	0.842	0.47
424_E	583_I	0.840	0.47
563_G	572_P	0.838	0.47
208_Y	212_V	0.838	0.47
108_A	207_L	0.835	0.47
466_Y	707_I	0.833	0.46
45_A	72_I	0.832	0.46
475_Q	478_E	0.830	0.46
60_D	100_D	0.828	0.46
430_G	576_E	0.828	0.46
203_F	217_M	0.825	0.46
386_H	420_T	0.825	0.46
253_V	258_P	0.824	0.46
521_L	534_V	0.822	0.45
328_S	415_S	0.820	0.45
644_V	663_V	0.819	0.45
520_V	524_A	0.818	0.45
233_S	651_V	0.817	0.45
32_H	37_L	0.817	0.45
529_E	533_D	0.817	0.45
192_W	195_S	0.815	0.45
246_A	351_D	0.814	0.45
46_G	250_L	0.811	0.45
636_H	639_A	0.810	0.45
28_A	128_Q	0.809	0.44
29_H	33_G	0.808	0.44
168_L	466_Y	0.807	0.44
669_V	675_F	0.807	0.44
280_I	284_M	0.806	0.44
496_S	582_L	0.802	0.44
98_H	101_F	0.802	0.44
572_P	635_E	0.802	0.44
89_L	354_P	0.802	0.44
442_L	496_S	0.801	0.44
133_V	343_M	0.801	0.44
26_I	248_V	0.799	0.44
145_L	172_I	0.799	0.44
567_S	610_V	0.799	0.44
289_E	542_I	0.798	0.44
72_I	452_N	0.797	0.43
299_D	311_A	0.795	0.43
18_P	150_V	0.795	0.43
316_S	454_G	0.793	0.43
303_D	347_R	0.793	0.43
545_D	599_P	0.792	0.43
595_I	598_G	0.792	0.43
22_R	28_A	0.791	0.43
200_T	625_I	0.788	0.43
534_V	544_I	0.788	0.43
38_T	46_G	0.788	0.43
368_I	684_E	0.787	0.43
152_R	680_R	0.787	0.43
519_E	524_A	0.786	0.43
483_N	597_R	0.786	0.43
37_L	41_L	0.783	0.42
349_E	578_V	0.781	0.42
29_H	129_T	0.781	0.42
547_T	552_H	0.781	0.42
415_S	630_I	0.780	0.42
40_N	44_G	0.779	0.42
97_G	438_G	0.779	0.42
549_G	558_E	0.776	0.42
253_V	262_D	0.775	0.42
591_H	597_R	0.775	0.42
528_K	532_Q	0.775	0.42
586_H	609_A	0.774	0.42
97_G	100_D	0.772	0.41
138_R	180_R	0.771	0.41
259_N	274_G	0.771	0.41
23_N	35_T	0.770	0.41
94_D	98_H	0.770	0.41
466_Y	621_L	0.769	0.41
64_D	452_N	0.768	0.41
455_I	488_F	0.768	0.41
668_P	685_G	0.767	0.41
100_D	105_V	0.767	0.41
409_E	596_H	0.766	0.41
522_Q	525_G	0.765	0.41
556_T	602_V	0.763	0.41
107_R	112_V	0.763	0.41
483_N	596_H	0.762	0.41
479_G	605_A	0.761	0.41
564_L	583_I	0.759	0.40
508_V	585_L	0.759	0.40
39_D	60_D	0.759	0.40
78_S	394_K	0.759	0.40
179_I	205_S	0.759	0.40
678_D	682_A	0.758	0.40
395_S	410_T	0.757	0.40
609_A	642_G	0.755	0.40
679_I	688_S	0.754	0.40
114_G	258_P	0.753	0.40
35_T	39_D	0.752	0.40
519_E	529_E	0.752	0.40
98_H	152_R	0.752	0.40
313_R	442_L	0.750	0.40
477_V	608_D	0.750	0.40
465_V	626_Q	0.749	0.40
523_E	526_M	0.749	0.40
100_D	390_P	0.747	0.40
414_V	445_Q	0.746	0.39
599_P	603_I	0.745	0.39
275_D	279_E	0.744	0.39
113_D	120_D	0.744	0.39
405_P	408_I	0.743	0.39
300_I	364_L	0.742	0.39
286_L	290_D	0.740	0.39
299_D	448_R	0.739	0.39
650_R	666_I	0.739	0.39
59_M	443_E	0.738	0.39
693_N	701_D	0.738	0.39
629_R	664_E	0.738	0.39
113_D	313_R	0.733	0.38
310_A	315_F	0.733	0.38
567_S	585_L	0.733	0.38
339_V	350_V	0.733	0.38
23_N	33_G	0.730	0.38
283_S	288_D	0.730	0.38
517_R	520_V	0.730	0.38
41_L	79_M	0.730	0.38
498_D	501_E	0.728	0.38
446_T	459_T	0.727	0.38
289_E	434_I	0.725	0.38
26_I	542_I	0.724	0.38
235_K	242_Q	0.724	0.38
434_I	577_P	0.723	0.38
203_F	209_K	0.723	0.38
77_V	95_T	0.721	0.38
315_F	488_F	0.721	0.38
409_E	413_Q	0.720	0.37
647_R	678_D	0.720	0.37
704_Q	707_I	0.720	0.37
38_T	244_P	0.720	0.37
529_E	532_Q	0.718	0.37
490_I	613_A	0.718	0.37
65_E	71_T	0.718	0.37
627_D	690_N	0.717	0.37
403_D	456_P	0.717	0.37
295_L	420_T	0.717	0.37
526_M	529_E	0.717	0.37
320_E	621_L	0.716	0.37
123_E	156_E	0.715	0.37
150_V	168_L	0.714	0.37
58_A	69_G	0.713	0.37
207_L	605_A	0.713	0.37
629_R	662_V	0.712	0.37
327_V	470_P	0.712	0.37
42_L	599_P	0.712	0.37
75_A	112_V	0.710	0.37
122_V	358_I	0.710	0.37
630_I	687_A	0.709	0.37
274_G	281_A	0.708	0.37
111_A	394_K	0.707	0.36
472_S	618_D	0.707	0.36
429_T	659_D	0.706	0.36
490_I	585_L	0.706	0.36
641_S	661_M	0.706	0.36
171_V	656_Q	0.706	0.36
564_L	576_E	0.704	0.36
89_L	470_P	0.703	0.36
504_R	527_D	0.702	0.36
47_M	77_V	0.702	0.36
31_D	128_Q	0.702	0.36
504_R	621_L	0.701	0.36
90_I	291_G	0.700	0.36
203_F	213_S	0.700	0.36
484_R	487_K	0.699	0.36
68_R	105_V	0.698	0.36
43_A	48_I	0.698	0.36
19_E	229_D	0.698	0.36
103_G	441_H	0.698	0.36
325_L	412_R	0.697	0.36
38_T	250_L	0.696	0.36
632_V	675_F	0.695	0.36
533_D	545_D	0.695	0.36
567_S	614_L	0.695	0.36
199_G	488_F	0.694	0.35
365_K	416_K	0.694	0.35
625_I	628_V	0.694	0.35
53_A	75_A	0.693	0.35
31_D	100_D	0.692	0.35
264_Q	267_R	0.692	0.35
31_D	60_D	0.692	0.35
496_S	580_G	0.692	0.35
456_P	473_D	0.690	0.35
666_I	695_G	0.690	0.35
325_L	336_V	0.689	0.35
199_G	215_P	0.689	0.35
469_T	683_T	0.689	0.35
279_E	375_N	0.689	0.35
394_K	459_T	0.689	0.35
205_S	212_V	0.688	0.35
323_Q	375_N	0.688	0.35
39_D	43_A	0.688	0.35
632_V	640_A	0.688	0.35
253_V	257_F	0.687	0.35
499_V	540_R	0.687	0.35
549_G	552_H	0.687	0.35
665_G	691_T	0.686	0.35
255_E	351_D	0.686	0.35
198_D	236_R	0.685	0.35
248_V	256_H	0.685	0.35
324_E	335_R	0.684	0.35
297_V	390_P	0.684	0.35
71_T	74_A	0.683	0.35
329_G	371_S	0.683	0.35
229_D	585_L	0.682	0.35
212_V	218_Q	0.681	0.35
79_M	92_L	0.681	0.35
68_R	438_G	0.681	0.35
706_E	709_M	0.680	0.34
36_T	141_V	0.679	0.34
287_V	297_V	0.678	0.34
125_A	134_R	0.677	0.34
217_M	225_G	0.675	0.34
534_V	547_T	0.675	0.34
567_S	578_V	0.675	0.34
594_A	597_R	0.674	0.34
27_A	262_D	0.674	0.34
521_L	526_M	0.674	0.34
611_H	616_D	0.673	0.34
319_L	434_I	0.673	0.34
358_I	464_V	0.672	0.34
489_Y	546_D	0.672	0.34
458_T	532_Q	0.671	0.34
62_E	104_D	0.671	0.34
36_T	177_E	0.671	0.34
39_D	65_E	0.670	0.34
27_A	132_V	0.670	0.34
547_T	550_I	0.669	0.34
390_P	630_I	0.669	0.34
191_D	198_D	0.669	0.34
338_S	351_D	0.669	0.34
219_R	222_M	0.668	0.34
211_G	434_I	0.668	0.34
544_I	584_R	0.667	0.34
20_Q	86_D	0.667	0.34
679_I	694_A	0.666	0.33
232_R	235_K	0.666	0.33
590_L	595_I	0.666	0.33
32_H	54_G	0.665	0.33
502_E	617_A	0.665	0.33
68_R	680_R	0.664	0.33
444_V	448_R	0.663	0.33
66_Q	69_G	0.662	0.33
485_H	555_E	0.662	0.33
108_A	336_V	0.662	0.33
188_D	193_T	0.661	0.33
108_A	421_I	0.661	0.33
158_Q	396_I	0.659	0.33
499_V	503_I	0.659	0.33
123_E	149_K	0.658	0.33
628_V	665_G	0.657	0.33
134_R	653_D	0.657	0.33
140_G	495_L	0.656	0.33
583_I	613_A	0.655	0.33
229_D	350_V	0.655	0.33
256_H	297_V	0.655	0.33
631_D	656_Q	0.654	0.33
54_G	71_T	0.654	0.33
159_E	397_E	0.654	0.33
492_V	702_N	0.653	0.33
429_T	463_I	0.653	0.33
543_F	621_L	0.653	0.33
27_A	37_L	0.653	0.33
78_S	117_V	0.652	0.32
289_E	455_I	0.652	0.32
319_L	498_D	0.652	0.32
146_F	358_I	0.651	0.32
648_R	671_E	0.651	0.32
95_T	369_A	0.649	0.32
397_E	680_R	0.649	0.32
205_S	628_V	0.648	0.32
42_L	344_G	0.648	0.32
508_V	518_R	0.647	0.32
340_G	361_V	0.646	0.32
304_P	501_E	0.645	0.32
480_V	561_V	0.645	0.32
271_V	667_A	0.644	0.32
620_R	658_G	0.644	0.32
419_P	683_T	0.643	0.32
320_E	351_D	0.643	0.32
628_V	640_A	0.643	0.32
620_R	698_V	0.642	0.32
99_V	128_Q	0.642	0.32
283_S	287_V	0.641	0.32
199_G	203_F	0.641	0.32
156_E	163_E	0.640	0.32
411_L	668_P	0.640	0.32
64_D	448_R	0.640	0.32
222_M	226_D	0.640	0.32
483_N	601_Q	0.639	0.32
526_M	533_D	0.639	0.32
59_M	70_I	0.637	0.31
188_D	192_W	0.637	0.31
650_R	678_D	0.636	0.31
88_H	234_D	0.636	0.31
217_M	220_T	0.636	0.31
142_K	215_P	0.635	0.31
96_P	101_F	0.635	0.31
347_R	391_V	0.634	0.31
128_Q	464_V	0.634	0.31
605_A	612_R	0.633	0.31
25_A	30_V	0.633	0.31
168_L	172_I	0.633	0.31
62_E	448_R	0.632	0.31
202_A	651_V	0.632	0.31
212_V	217_M	0.632	0.31
252_M	261_I	0.632	0.31
424_E	677_S	0.630	0.31
44_G	421_I	0.629	0.31
542_I	651_V	0.629	0.31
183_T	186_K	0.629	0.31
290_D	663_V	0.628	0.31
253_V	256_H	0.628	0.31
167_R	360_A	0.627	0.31
376_E	590_L	0.627	0.31
632_V	637_M	0.627	0.31
371_S	626_Q	0.627	0.31
619_I	648_R	0.625	0.31
335_R	339_V	0.624	0.30
526_M	534_V	0.622	0.30
55_Q	69_G	0.621	0.30
56_Q	66_Q	0.621	0.30
470_P	619_I	0.620	0.30
563_G	694_A	0.620	0.30
227_I	336_V	0.619	0.30
648_R	694_A	0.619	0.30
31_D	36_T	0.617	0.30
62_E	70_I	0.617	0.30
352_E	589_R	0.615	0.30
431_E	643_E	0.615	0.30
482_P	602_V	0.614	0.30
556_T	560_V	0.613	0.30
350_V	380_P	0.612	0.30
130_E	440_L	0.611	0.30
325_L	552_H	0.611	0.30
429_T	477_V	0.610	0.30
249_V	253_V	0.610	0.30
287_V	291_G	0.610	0.30
150_V	341_I	0.610	0.30
150_V	335_R	0.608	0.29
255_E	663_V	0.607	0.29
318_T	354_P	0.606	0.29
114_G	253_V	0.604	0.29
233_S	237_E	0.603	0.29
51_D	396_I	0.603	0.29
104_D	680_R	0.602	0.29
354_P	663_V	0.602	0.29
68_R	104_D	0.602	0.29
294_V	378_M	0.601	0.29
26_I	40_N	0.601	0.29
258_P	355_A	0.600	0.29
100_D	418_D	0.600	0.29
592_E	605_A	0.598	0.29
90_I	652_D	0.597	0.29
484_R	602_V	0.597	0.29
332_G	410_T	0.597	0.29
496_S	663_V	0.596	0.29
109_M	307_G	0.595	0.29
232_R	236_R	0.595	0.29
401_M	548_K	0.592	0.28
585_L	631_D	0.592	0.28
183_T	229_D	0.591	0.28
25_A	66_Q	0.591	0.28
35_T	69_G	0.590	0.28
80_T	87_D	0.590	0.28
524_A	531_S	0.589	0.28
650_R	697_R	0.589	0.28
701_D	705_R	0.589	0.28
19_E	499_V	0.588	0.28
97_G	101_F	0.588	0.28
506_G	537_I	0.587	0.28
374_S	378_M	0.586	0.28
79_M	154_I	0.586	0.28
491_T	584_R	0.586	0.28
146_F	246_A	0.586	0.28
526_M	530_T	0.585	0.28
214_M	556_T	0.584	0.28
539_G	543_F	0.584	0.28
486_N	597_R	0.583	0.28
481_S	489_Y	0.583	0.28
407_L	621_L	0.583	0.28
38_T	443_E	0.582	0.28
368_I	371_S	0.582	0.28
283_S	651_V	0.582	0.28
567_S	575_A	0.580	0.28
32_H	136_A	0.580	0.28
475_Q	585_L	0.580	0.28
462_P	648_R	0.579	0.27
565_T	621_L	0.578	0.27
572_P	691_T	0.578	0.27
258_P	262_D	0.578	0.27
643_E	673_I	0.577	0.27
524_A	530_T	0.576	0.27
129_T	136_A	0.575	0.27
615_I	651_V	0.575	0.27
60_D	97_G	0.573	0.27
418_D	444_V	0.572	0.27
92_L	122_V	0.572	0.27
144_T	374_S	0.572	0.27
199_G	252_M	0.572	0.27
55_Q	109_M	0.571	0.27
73_D	672_M	0.570	0.27
341_I	679_I	0.570	0.27
215_P	255_E	0.570	0.27
221_G	226_D	0.570	0.27
48_I	56_Q	0.570	0.27
698_V	703_L	0.569	0.27
573_L	615_I	0.569	0.27
524_A	527_D	0.569	0.27
502_E	506_G	0.569	0.27
84_E	560_V	0.568	0.27
105_V	258_P	0.567	0.27
585_L	651_V	0.567	0.27
59_M	436_G	0.566	0.27
105_V	135_Q	0.565	0.27
65_E	438_G	0.565	0.27
53_A	71_T	0.565	0.27
25_A	37_L	0.564	0.26
105_V	125_A	0.563	0.26
553_L	663_V	0.563	0.26
262_D	351_D	0.563	0.26
131_T	134_R	0.562	0.26
42_L	58_A	0.562	0.26
106_T	139_E	0.562	0.26
432_H	675_F	0.561	0.26
493_E	542_I	0.561	0.26
588_A	648_R	0.561	0.26
171_V	338_S	0.561	0.26
262_D	375_N	0.561	0.26
573_L	619_I	0.560	0.26
27_A	30_V	0.560	0.26
70_I	100_D	0.559	0.26
409_E	412_R	0.558	0.26
585_L	607_R	0.558	0.26
315_F	423_I	0.558	0.26
130_E	147_I	0.558	0.26
637_M	661_M	0.557	0.26
319_L	409_E	0.557	0.26
508_V	517_R	0.556	0.26
163_E	637_M	0.556	0.26
333_K	655_Y	0.555	0.26
672_M	691_T	0.555	0.26
297_V	312_G	0.555	0.26
306_A	347_R	0.555	0.26
481_S	484_R	0.554	0.26
493_E	586_H	0.554	0.26
39_D	79_M	0.553	0.26
505_L	560_V	0.553	0.26
115_A	683_T	0.553	0.26
59_M	77_V	0.552	0.26
43_A	53_A	0.551	0.26
394_K	564_L	0.549	0.26
203_F	214_M	0.549	0.26
114_G	363_G	0.549	0.26
523_E	529_E	0.549	0.26
603_I	608_D	0.548	0.25
483_N	541_N	0.548	0.25
105_V	114_G	0.547	0.25
216_S	381_F	0.547	0.25
71_T	76_N	0.547	0.25
353_V	459_T	0.547	0.25
236_R	239_L	0.546	0.25
450_E	459_T	0.546	0.25
667_A	695_G	0.546	0.25
204_G	318_T	0.545	0.25
68_R	99_V	0.545	0.25
150_V	247_D	0.544	0.25
456_P	490_I	0.544	0.25
631_D	670_D	0.544	0.25
653_D	661_M	0.543	0.25
39_D	58_A	0.543	0.25
95_T	105_V	0.542	0.25
417_E	448_R	0.541	0.25
425_I	674_G	0.539	0.25
480_V	587_D	0.539	0.25
72_I	75_A	0.538	0.25
45_A	79_M	0.538	0.25
700_A	704_Q	0.538	0.25
39_D	73_D	0.538	0.25
215_P	560_V	0.538	0.25
106_T	110_R	0.538	0.25
32_H	53_A	0.537	0.25
198_D	376_E	0.536	0.25
166_E	170_S	0.536	0.25
289_E	361_V	0.535	0.25
64_D	68_R	0.535	0.25
120_D	123_E	0.534	0.25
280_I	364_L	0.534	0.25
29_H	105_V	0.534	0.25
108_A	621_L	0.534	0.25
393_T	466_Y	0.532	0.25
572_P	609_A	0.532	0.25
108_A	695_G	0.531	0.24
319_L	396_I	0.531	0.24
144_T	202_A	0.529	0.24
75_A	698_V	0.529	0.24
438_G	685_G	0.529	0.24
89_L	139_E	0.529	0.24
130_E	679_I	0.528	0.24
39_D	101_F	0.528	0.24
451_R	454_G	0.527	0.24
495_L	545_D	0.527	0.24
32_H	41_L	0.527	0.24
248_V	257_F	0.527	0.24
502_E	520_V	0.526	0.24
373_V	414_V	0.526	0.24
525_G	528_K	0.526	0.24
122_V	663_V	0.525	0.24
358_I	411_L	0.525	0.24
36_T	357_N	0.524	0.24
462_P	469_T	0.524	0.24
481_S	549_G	0.524	0.24
319_L	324_E	0.523	0.24
123_E	153_L	0.522	0.24
25_A	46_G	0.522	0.24
339_V	629_R	0.521	0.24
480_V	485_H	0.521	0.24
27_A	56_Q	0.521	0.24
277_D	291_G	0.520	0.24
525_G	529_E	0.520	0.24
219_R	285_R	0.518	0.24
74_A	298_T	0.518	0.24
35_T	595_I	0.518	0.24
521_L	531_S	0.518	0.24
481_S	485_H	0.517	0.24
61_T	127_P	0.517	0.24
88_H	679_I	0.517	0.24
454_G	651_V	0.517	0.24
518_R	585_L	0.516	0.24
151_D	438_G	0.516	0.24
22_R	33_G	0.516	0.24
60_D	438_G	0.516	0.24
214_M	219_R	0.515	0.24
319_L	339_V	0.515	0.24
116_L	257_F	0.514	0.23
59_M	66_Q	0.514	0.23
75_A	107_R	0.513	0.23
440_L	444_V	0.512	0.23
29_H	42_L	0.512	0.23
111_A	440_L	0.512	0.23
115_A	625_I	0.512	0.23
120_D	152_R	0.512	0.23
183_T	456_P	0.512	0.23
359_A	364_L	0.511	0.23
507_E	511_D	0.511	0.23
29_H	149_K	0.511	0.23
277_D	280_I	0.511	0.23
213_S	222_M	0.511	0.23
94_D	100_D	0.510	0.23
116_L	662_V	0.509	0.23
374_S	398_A	0.509	0.23
403_D	637_M	0.509	0.23
567_S	580_G	0.508	0.23
110_R	467_R	0.508	0.23
510_M	518_R	0.508	0.23
42_L	284_M	0.508	0.23
590_L	698_V	0.508	0.23
542_I	697_R	0.508	0.23
141_V	422_S	0.507	0.23
560_V	602_V	0.507	0.23
167_R	249_V	0.507	0.23
128_Q	315_F	0.506	0.23
69_G	632_V	0.506	0.23
65_E	94_D	0.505	0.23
100_D	132_V	0.505	0.23
87_D	117_V	0.504	0.23
466_Y	696_F	0.504	0.23
21_I	455_I	0.504	0.23
254_A	376_E	0.504	0.23
68_R	78_S	0.504	0.23
92_L	95_T	0.504	0.23
130_E	686_R	0.503	0.23
105_V	418_D	0.503	0.23
630_I	649_G	0.502	0.23
163_E	544_I	0.501	0.23
98_H	113_D	0.501	0.23
21_I	385_D	0.501	0.23
221_G	326_Y	0.501	0.23
74_A	77_V	0.500	0.23
207_L	388_S	0.500	0.23

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4w224	1	0.9918	100	0.274	Contact Map
1n0uA	1	0.9602	100	0.284	Contact Map
4kiyV	1	0.886	100	0.376	Contact Map
1darA	1	0.7898	100	0.382	Contact Map
2xexA	1	0.8736	100	0.383	Contact Map
4fn5A	1	0.8599	100	0.392	Contact Map
2dy1A	1	0.8516	100	0.424	Contact Map
3j25A	1	0.8516	100	0.441	Contact Map
4zciA	1	0.6415	100	0.571	Contact Map
2yweA	1	0.6497	100	0.571	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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