GREMLIN Database
EF2 - Elongation factor 2
UniProt: Q9HM85 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 728 (686)
Sequences: 1374 (824)
Seq/√Len: 31.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
353_V359_A6.8661.00
121_A147_I6.2411.00
320_E352_E5.5551.00
319_L361_V4.4481.00
450_E456_P4.0521.00
439_E674_G3.9711.00
28_A31_D3.9491.00
132_V135_Q3.7931.00
583_I610_V3.7551.00
447_Q451_R3.7391.00
42_L77_V3.5881.00
25_A112_V3.4791.00
353_V357_N3.4501.00
421_I445_Q3.3891.00
283_S292_E3.3251.00
24_I253_V3.2871.00
295_L319_L3.1361.00
366_D369_A3.1161.00
61_T75_A3.1111.00
626_Q669_V2.9951.00
491_T586_H2.9811.00
630_I640_A2.9711.00
146_F204_G2.9441.00
367_A371_S2.8841.00
63_E67_E2.8491.00
119_V145_L2.8011.00
319_L336_V2.5811.00
29_H32_H2.5611.00
276_A281_A2.5341.00
410_T449_I2.5251.00
606_T610_V2.5191.00
466_Y670_D2.5051.00
667_A675_F2.5030.99
152_R156_E2.5000.99
38_T59_M2.4710.99
517_R521_L2.4590.99
293_V325_L2.4500.99
37_L249_V2.4430.99
615_I619_I2.4200.99
392_I673_I2.4030.99
109_M115_A2.3790.99
297_V310_A2.3780.99
469_T620_R2.3760.99
644_V649_G2.3750.99
27_A115_A2.2740.99
578_V614_L2.2560.99
535_E539_G2.2500.99
502_E524_A2.2360.99
627_D664_E2.2210.99
623_E648_R2.2020.99
283_S291_G2.1920.99
609_A613_A2.1830.99
403_D406_K2.1650.99
446_T450_E2.1570.98
76_N358_I2.1550.98
339_V361_V2.1370.98
497_D501_E2.1310.98
194_V200_T2.0930.98
305_H309_I2.0700.98
543_F585_L2.0660.98
252_M256_H2.0630.98
612_R616_D2.0500.98
519_E522_Q2.0440.98
295_L314_V2.0400.98
643_E675_F2.0310.98
305_H308_E2.0310.98
518_R521_L2.0280.98
647_R674_G1.9960.97
203_F212_V1.9940.97
680_R685_G1.9840.97
196_V201_V1.9790.97
646_G678_D1.9550.97
189_I192_W1.9530.97
288_D291_G1.9340.97
23_N26_I1.9330.97
294_V374_S1.9320.97
288_D292_E1.9240.97
105_V132_V1.9010.97
196_V200_T1.8990.97
560_V606_T1.8790.96
501_E505_L1.8790.96
31_D71_T1.8780.96
104_D299_D1.8770.96
119_V129_T1.8720.96
354_P396_I1.8690.96
110_R135_Q1.8680.96
393_T433_L1.8660.96
620_R703_L1.8420.96
217_M221_G1.8350.96
28_A38_T1.8150.95
17_N20_Q1.8070.95
125_A129_T1.8000.95
263_A294_V1.7950.95
480_V591_H1.7920.95
350_V353_V1.7920.95
566_D603_I1.7860.95
341_I350_V1.7780.95
60_D65_E1.7730.95
687_A693_N1.7680.95
27_A136_A1.7670.95
309_I360_A1.7610.95
250_L253_V1.7590.95
132_V136_A1.7460.94
579_E696_F1.7440.94
492_V583_I1.7370.94
62_E66_Q1.7350.94
144_T252_M1.7320.94
31_D70_I1.7220.94
439_E647_R1.7040.94
490_I609_A1.6900.93
705_R709_M1.6830.93
26_I32_H1.6710.93
667_A672_M1.6610.93
121_A168_L1.6540.93
321_K351_D1.6500.93
22_R260_P1.6460.92
572_P614_L1.6370.92
72_I444_V1.6340.92
81_H251_D1.6330.92
114_G257_F1.6240.92
116_L253_V1.6150.92
196_V203_F1.6110.92
98_H438_G1.6100.92
160_G163_E1.5940.91
111_A298_T1.5920.91
28_A71_T1.5900.91
26_I118_V1.5680.90
90_I585_L1.5670.90
147_I171_V1.5620.90
381_F384_I1.5590.90
399_Q456_P1.5580.90
563_G610_V1.5570.90
364_L373_V1.5540.90
314_V359_A1.5510.90
130_E136_A1.5500.90
482_P605_A1.5490.90
297_V336_V1.5450.90
560_V563_G1.5440.90
603_I607_R1.5410.90
145_L194_V1.5400.90
325_L373_V1.5390.90
282_E286_L1.5300.89
37_L118_V1.5240.89
295_L361_V1.5120.89
666_I697_R1.4970.88
65_E68_R1.4930.88
110_R139_E1.4860.88
75_A344_G1.4860.88
647_R668_P1.4860.88
196_V212_V1.4810.88
608_D611_H1.4780.88
102_G128_Q1.4770.88
627_D692_E1.4700.87
29_H75_A1.4700.87
59_M71_T1.4660.87
320_E323_Q1.4630.87
293_V318_T1.4630.87
534_V542_I1.4630.87
325_L346_E1.4610.87
493_E584_R1.4560.87
277_D281_A1.4550.87
201_V212_V1.4450.86
122_V152_R1.4320.86
202_A252_M1.4050.85
41_L176_N1.4040.85
338_S362_T1.4040.85
189_I193_T1.4010.85
248_V252_M1.4000.85
394_K446_T1.3990.85
22_R29_H1.3910.84
338_S349_E1.3900.84
336_V371_S1.3890.84
495_L499_V1.3870.84
364_L367_A1.3870.84
230_L238_E1.3860.84
25_A28_A1.3850.84
94_D97_G1.3740.83
500_L540_R1.3730.83
53_A57_L1.3700.83
527_D532_Q1.3630.83
230_L235_K1.3620.83
292_E316_S1.3560.83
418_D441_H1.3560.83
220_T224_F1.3520.82
117_V129_T1.3520.82
297_V522_Q1.3480.82
490_I606_T1.3440.82
281_A284_M1.3430.82
400_N403_D1.3390.82
195_S198_D1.3380.82
21_I91_N1.3380.82
628_V675_F1.3340.82
312_G361_V1.3340.82
57_L60_D1.3260.81
150_V210_W1.3250.81
24_I90_I1.3230.81
397_E458_T1.3220.81
403_D455_I1.3220.81
30_V71_T1.3180.81
520_V523_E1.3140.81
218_Q221_G1.3140.81
281_A285_R1.3130.80
276_A285_R1.3090.80
77_V343_M1.3040.80
128_Q131_T1.3020.80
563_G567_S1.2990.80
128_Q135_Q1.2990.80
27_A117_V1.2940.79
669_V672_M1.2900.79
38_T92_L1.2850.79
482_P598_G1.2840.79
488_F609_A1.2820.79
196_V217_M1.2760.79
159_E401_M1.2750.78
282_E285_R1.2740.78
98_H120_D1.2720.78
57_L66_Q1.2690.78
71_T77_V1.2670.78
102_G106_T1.2570.77
473_D493_E1.2550.77
480_V487_K1.2540.77
507_E523_E1.2540.77
190_E232_R1.2530.77
24_I453_Q1.2510.77
221_G224_F1.2490.77
578_V588_A1.2470.77
62_E73_D1.2370.76
327_V371_S1.2260.76
630_I644_V1.2240.76
28_A33_G1.2180.75
318_T495_L1.2110.75
118_V319_L1.2090.75
250_L257_F1.2010.74
176_N205_S1.2010.74
23_N28_A1.2000.74
634_S637_M1.1970.74
253_V260_P1.1930.74
259_N262_D1.1930.74
425_I621_L1.1880.73
397_E430_G1.1870.73
250_L260_P1.1860.73
70_I98_H1.1830.73
71_T128_Q1.1820.73
414_V421_I1.1790.73
147_I227_I1.1750.72
278_S283_S1.1740.72
521_L525_G1.1710.72
22_R114_G1.1690.72
379_T382_E1.1670.72
31_D34_K1.1650.72
92_L108_A1.1620.72
394_K460_G1.1570.71
60_D68_R1.1490.71
628_V691_T1.1470.71
318_T352_E1.1460.71
679_I695_G1.1450.70
39_D57_L1.1450.70
52_T55_Q1.1440.70
81_H85_G1.1430.70
518_R531_S1.1390.70
82_E87_D1.1350.70
115_A649_G1.1260.69
99_V131_T1.1210.69
431_E454_G1.1190.69
557_M585_L1.1140.68
627_D694_A1.1140.68
27_A109_M1.1120.68
90_I357_N1.1060.68
60_D69_G1.1010.67
469_T622_L1.0990.67
203_F206_A1.0910.67
102_G135_Q1.0900.67
32_H39_D1.0880.66
414_V449_I1.0860.66
144_T257_F1.0850.66
249_V257_F1.0850.66
221_G396_I1.0830.66
559_L599_P1.0790.66
314_V353_V1.0770.66
60_D70_I1.0750.66
295_L359_A1.0750.66
128_Q132_V1.0750.66
449_I453_Q1.0690.65
27_A36_T1.0690.65
450_E453_Q1.0670.65
64_D447_Q1.0650.65
291_G316_S1.0630.65
28_A32_H1.0620.65
517_R522_Q1.0590.64
278_S284_M1.0540.64
117_V132_V1.0530.64
518_R528_K1.0520.64
111_A141_V1.0510.64
200_T203_F1.0510.64
251_D255_E1.0500.64
496_S526_M1.0480.64
528_K531_S1.0470.63
295_L312_G1.0440.63
57_L68_R1.0430.63
89_L357_N1.0420.63
497_D505_L1.0410.63
448_R452_N1.0410.63
53_A66_Q1.0400.63
82_E85_G1.0380.63
74_A417_E1.0360.63
412_R469_T1.0310.62
693_N696_F1.0290.62
68_R397_E1.0260.62
247_D260_P1.0250.62
321_K349_E1.0250.62
65_E69_G1.0250.62
250_L258_P1.0240.62
674_G678_D1.0230.62
129_T145_L1.0220.62
32_H119_V1.0220.62
106_T135_Q1.0200.61
201_V205_S1.0190.61
421_I434_I1.0180.61
219_R223_D1.0160.61
483_N486_N1.0140.61
24_I466_Y1.0130.61
23_N91_N1.0120.61
549_G591_H1.0090.61
88_H254_A1.0080.60
234_D238_E1.0060.60
203_F210_W1.0040.60
554_N667_A1.0030.60
250_L435_S1.0010.60
28_A34_K0.9990.60
500_L580_G0.9990.60
222_M254_A0.9980.60
258_P263_A0.9940.59
679_I685_G0.9900.59
632_V636_H0.9880.59
268_I276_A0.9870.59
68_R98_H0.9840.59
80_T150_V0.9840.59
527_D531_S0.9830.58
60_D66_Q0.9820.58
55_Q66_Q0.9810.58
595_I602_V0.9790.58
25_A109_M0.9750.58
512_M519_E0.9730.58
439_E673_I0.9730.58
49_S54_G0.9720.58
114_G132_V0.9700.57
196_V199_G0.9680.57
236_R270_T0.9680.57
116_L207_L0.9680.57
74_A93_I0.9650.57
361_V585_L0.9630.57
508_V520_V0.9620.57
640_A681_S0.9590.57
147_I563_G0.9570.56
206_A210_W0.9560.56
617_A623_E0.9550.56
133_V143_P0.9540.56
150_V663_V0.9540.56
68_R101_F0.9530.56
45_A78_S0.9520.56
37_L209_K0.9520.56
25_A31_D0.9500.56
128_Q418_D0.9490.56
319_L578_V0.9480.56
33_G36_T0.9460.56
61_T64_D0.9460.56
384_I621_L0.9460.56
434_I445_Q0.9430.55
597_R604_P0.9420.55
102_G108_A0.9380.55
44_G247_D0.9380.55
339_V442_L0.9290.54
535_E540_R0.9290.54
105_V149_K0.9280.54
434_I454_G0.9280.54
257_F674_G0.9270.54
67_E594_A0.9240.54
268_I281_A0.9210.54
116_L249_V0.9200.53
398_A577_P0.9200.53
340_G362_T0.9200.53
519_E525_G0.9180.53
530_T533_D0.9170.53
98_H104_D0.9170.53
205_S456_P0.9170.53
329_G332_G0.9160.53
73_D679_I0.9150.53
280_I283_S0.9150.53
286_L289_E0.9150.53
212_V221_G0.9100.53
62_E673_I0.9090.53
597_R601_Q0.9080.52
251_D257_F0.9080.52
26_I116_L0.9070.52
231_E255_E0.9070.52
91_N102_G0.9020.52
260_P313_R0.9010.52
37_L40_N0.8990.52
546_D584_R0.8980.52
247_D254_A0.8980.52
493_E582_L0.8980.52
136_A143_P0.8960.52
399_Q458_T0.8950.51
280_I285_R0.8950.51
319_L325_L0.8940.51
46_G71_T0.8930.51
64_D72_I0.8920.51
405_P604_P0.8920.51
484_R488_F0.8920.51
69_G440_L0.8890.51
132_V257_F0.8880.51
206_A214_M0.8880.51
310_A339_V0.8870.51
48_I343_M0.8860.51
476_E479_G0.8850.51
26_I38_T0.8830.50
98_H149_K0.8810.50
93_I112_V0.8800.50
260_P264_Q0.8800.50
619_I629_R0.8800.50
25_A107_R0.8780.50
277_D287_V0.8780.50
205_S430_G0.8780.50
590_L594_A0.8770.50
620_R702_N0.8740.50
585_L602_V0.8730.50
129_T419_P0.8700.49
327_V369_A0.8700.49
61_T66_Q0.8700.49
523_E530_T0.8690.49
60_D101_F0.8670.49
235_K238_E0.8670.49
63_E99_V0.8650.49
553_L557_M0.8630.49
274_G598_G0.8570.48
605_A609_A0.8560.48
260_P263_A0.8560.48
75_A122_V0.8540.48
291_G318_T0.8520.48
247_D314_V0.8520.48
65_E101_F0.8500.48
473_D491_T0.8480.48
314_V354_P0.8460.47
319_L323_Q0.8450.47
696_F703_L0.8450.47
17_N21_I0.8430.47
36_T93_I0.8420.47
263_A267_R0.8420.47
424_E583_I0.8400.47
563_G572_P0.8380.47
208_Y212_V0.8380.47
108_A207_L0.8350.47
466_Y707_I0.8330.46
45_A72_I0.8320.46
475_Q478_E0.8300.46
60_D100_D0.8280.46
430_G576_E0.8280.46
203_F217_M0.8250.46
386_H420_T0.8250.46
253_V258_P0.8240.46
521_L534_V0.8220.45
328_S415_S0.8200.45
644_V663_V0.8190.45
520_V524_A0.8180.45
233_S651_V0.8170.45
32_H37_L0.8170.45
529_E533_D0.8170.45
192_W195_S0.8150.45
246_A351_D0.8140.45
46_G250_L0.8110.45
636_H639_A0.8100.45
28_A128_Q0.8090.44
29_H33_G0.8080.44
168_L466_Y0.8070.44
669_V675_F0.8070.44
280_I284_M0.8060.44
496_S582_L0.8020.44
98_H101_F0.8020.44
572_P635_E0.8020.44
89_L354_P0.8020.44
442_L496_S0.8010.44
133_V343_M0.8010.44
26_I248_V0.7990.44
145_L172_I0.7990.44
567_S610_V0.7990.44
289_E542_I0.7980.44
72_I452_N0.7970.43
299_D311_A0.7950.43
18_P150_V0.7950.43
316_S454_G0.7930.43
303_D347_R0.7930.43
545_D599_P0.7920.43
595_I598_G0.7920.43
22_R28_A0.7910.43
200_T625_I0.7880.43
534_V544_I0.7880.43
38_T46_G0.7880.43
368_I684_E0.7870.43
152_R680_R0.7870.43
519_E524_A0.7860.43
483_N597_R0.7860.43
37_L41_L0.7830.42
349_E578_V0.7810.42
29_H129_T0.7810.42
547_T552_H0.7810.42
415_S630_I0.7800.42
40_N44_G0.7790.42
97_G438_G0.7790.42
549_G558_E0.7760.42
253_V262_D0.7750.42
591_H597_R0.7750.42
528_K532_Q0.7750.42
586_H609_A0.7740.42
97_G100_D0.7720.41
138_R180_R0.7710.41
259_N274_G0.7710.41
23_N35_T0.7700.41
94_D98_H0.7700.41
466_Y621_L0.7690.41
64_D452_N0.7680.41
455_I488_F0.7680.41
668_P685_G0.7670.41
100_D105_V0.7670.41
409_E596_H0.7660.41
522_Q525_G0.7650.41
556_T602_V0.7630.41
107_R112_V0.7630.41
483_N596_H0.7620.41
479_G605_A0.7610.41
564_L583_I0.7590.40
508_V585_L0.7590.40
39_D60_D0.7590.40
78_S394_K0.7590.40
179_I205_S0.7590.40
678_D682_A0.7580.40
395_S410_T0.7570.40
609_A642_G0.7550.40
679_I688_S0.7540.40
114_G258_P0.7530.40
35_T39_D0.7520.40
519_E529_E0.7520.40
98_H152_R0.7520.40
313_R442_L0.7500.40
477_V608_D0.7500.40
465_V626_Q0.7490.40
523_E526_M0.7490.40
100_D390_P0.7470.40
414_V445_Q0.7460.39
599_P603_I0.7450.39
275_D279_E0.7440.39
113_D120_D0.7440.39
405_P408_I0.7430.39
300_I364_L0.7420.39
286_L290_D0.7400.39
299_D448_R0.7390.39
650_R666_I0.7390.39
59_M443_E0.7380.39
693_N701_D0.7380.39
629_R664_E0.7380.39
113_D313_R0.7330.38
310_A315_F0.7330.38
567_S585_L0.7330.38
339_V350_V0.7330.38
23_N33_G0.7300.38
283_S288_D0.7300.38
517_R520_V0.7300.38
41_L79_M0.7300.38
498_D501_E0.7280.38
446_T459_T0.7270.38
289_E434_I0.7250.38
26_I542_I0.7240.38
235_K242_Q0.7240.38
434_I577_P0.7230.38
203_F209_K0.7230.38
77_V95_T0.7210.38
315_F488_F0.7210.38
409_E413_Q0.7200.37
647_R678_D0.7200.37
704_Q707_I0.7200.37
38_T244_P0.7200.37
529_E532_Q0.7180.37
490_I613_A0.7180.37
65_E71_T0.7180.37
627_D690_N0.7170.37
403_D456_P0.7170.37
295_L420_T0.7170.37
526_M529_E0.7170.37
320_E621_L0.7160.37
123_E156_E0.7150.37
150_V168_L0.7140.37
58_A69_G0.7130.37
207_L605_A0.7130.37
629_R662_V0.7120.37
327_V470_P0.7120.37
42_L599_P0.7120.37
75_A112_V0.7100.37
122_V358_I0.7100.37
630_I687_A0.7090.37
274_G281_A0.7080.37
111_A394_K0.7070.36
472_S618_D0.7070.36
429_T659_D0.7060.36
490_I585_L0.7060.36
641_S661_M0.7060.36
171_V656_Q0.7060.36
564_L576_E0.7040.36
89_L470_P0.7030.36
504_R527_D0.7020.36
47_M77_V0.7020.36
31_D128_Q0.7020.36
504_R621_L0.7010.36
90_I291_G0.7000.36
203_F213_S0.7000.36
484_R487_K0.6990.36
68_R105_V0.6980.36
43_A48_I0.6980.36
19_E229_D0.6980.36
103_G441_H0.6980.36
325_L412_R0.6970.36
38_T250_L0.6960.36
632_V675_F0.6950.36
533_D545_D0.6950.36
567_S614_L0.6950.36
199_G488_F0.6940.35
365_K416_K0.6940.35
625_I628_V0.6940.35
53_A75_A0.6930.35
31_D100_D0.6920.35
264_Q267_R0.6920.35
31_D60_D0.6920.35
496_S580_G0.6920.35
456_P473_D0.6900.35
666_I695_G0.6900.35
325_L336_V0.6890.35
199_G215_P0.6890.35
469_T683_T0.6890.35
279_E375_N0.6890.35
394_K459_T0.6890.35
205_S212_V0.6880.35
323_Q375_N0.6880.35
39_D43_A0.6880.35
632_V640_A0.6880.35
253_V257_F0.6870.35
499_V540_R0.6870.35
549_G552_H0.6870.35
665_G691_T0.6860.35
255_E351_D0.6860.35
198_D236_R0.6850.35
248_V256_H0.6850.35
324_E335_R0.6840.35
297_V390_P0.6840.35
71_T74_A0.6830.35
329_G371_S0.6830.35
229_D585_L0.6820.35
212_V218_Q0.6810.35
79_M92_L0.6810.35
68_R438_G0.6810.35
706_E709_M0.6800.34
36_T141_V0.6790.34
287_V297_V0.6780.34
125_A134_R0.6770.34
217_M225_G0.6750.34
534_V547_T0.6750.34
567_S578_V0.6750.34
594_A597_R0.6740.34
27_A262_D0.6740.34
521_L526_M0.6740.34
611_H616_D0.6730.34
319_L434_I0.6730.34
358_I464_V0.6720.34
489_Y546_D0.6720.34
458_T532_Q0.6710.34
62_E104_D0.6710.34
36_T177_E0.6710.34
39_D65_E0.6700.34
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338_S351_D0.6690.34
219_R222_M0.6680.34
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679_I694_A0.6660.33
232_R235_K0.6660.33
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32_H54_G0.6650.33
502_E617_A0.6650.33
68_R680_R0.6640.33
444_V448_R0.6630.33
66_Q69_G0.6620.33
485_H555_E0.6620.33
108_A336_V0.6620.33
188_D193_T0.6610.33
108_A421_I0.6610.33
158_Q396_I0.6590.33
499_V503_I0.6590.33
123_E149_K0.6580.33
628_V665_G0.6570.33
134_R653_D0.6570.33
140_G495_L0.6560.33
583_I613_A0.6550.33
229_D350_V0.6550.33
256_H297_V0.6550.33
631_D656_Q0.6540.33
54_G71_T0.6540.33
159_E397_E0.6540.33
492_V702_N0.6530.33
429_T463_I0.6530.33
543_F621_L0.6530.33
27_A37_L0.6530.33
78_S117_V0.6520.32
289_E455_I0.6520.32
319_L498_D0.6520.32
146_F358_I0.6510.32
648_R671_E0.6510.32
95_T369_A0.6490.32
397_E680_R0.6490.32
205_S628_V0.6480.32
42_L344_G0.6480.32
508_V518_R0.6470.32
340_G361_V0.6460.32
304_P501_E0.6450.32
480_V561_V0.6450.32
271_V667_A0.6440.32
620_R658_G0.6440.32
419_P683_T0.6430.32
320_E351_D0.6430.32
628_V640_A0.6430.32
620_R698_V0.6420.32
99_V128_Q0.6420.32
283_S287_V0.6410.32
199_G203_F0.6410.32
156_E163_E0.6400.32
411_L668_P0.6400.32
64_D448_R0.6400.32
222_M226_D0.6400.32
483_N601_Q0.6390.32
526_M533_D0.6390.32
59_M70_I0.6370.31
188_D192_W0.6370.31
650_R678_D0.6360.31
88_H234_D0.6360.31
217_M220_T0.6360.31
142_K215_P0.6350.31
96_P101_F0.6350.31
347_R391_V0.6340.31
128_Q464_V0.6340.31
605_A612_R0.6330.31
25_A30_V0.6330.31
168_L172_I0.6330.31
62_E448_R0.6320.31
202_A651_V0.6320.31
212_V217_M0.6320.31
252_M261_I0.6320.31
424_E677_S0.6300.31
44_G421_I0.6290.31
542_I651_V0.6290.31
183_T186_K0.6290.31
290_D663_V0.6280.31
253_V256_H0.6280.31
167_R360_A0.6270.31
376_E590_L0.6270.31
632_V637_M0.6270.31
371_S626_Q0.6270.31
619_I648_R0.6250.31
335_R339_V0.6240.30
526_M534_V0.6220.30
55_Q69_G0.6210.30
56_Q66_Q0.6210.30
470_P619_I0.6200.30
563_G694_A0.6200.30
227_I336_V0.6190.30
648_R694_A0.6190.30
31_D36_T0.6170.30
62_E70_I0.6170.30
352_E589_R0.6150.30
431_E643_E0.6150.30
482_P602_V0.6140.30
556_T560_V0.6130.30
350_V380_P0.6120.30
130_E440_L0.6110.30
325_L552_H0.6110.30
429_T477_V0.6100.30
249_V253_V0.6100.30
287_V291_G0.6100.30
150_V341_I0.6100.30
150_V335_R0.6080.29
255_E663_V0.6070.29
318_T354_P0.6060.29
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233_S237_E0.6030.29
51_D396_I0.6030.29
104_D680_R0.6020.29
354_P663_V0.6020.29
68_R104_D0.6020.29
294_V378_M0.6010.29
26_I40_N0.6010.29
258_P355_A0.6000.29
100_D418_D0.6000.29
592_E605_A0.5980.29
90_I652_D0.5970.29
484_R602_V0.5970.29
332_G410_T0.5970.29
496_S663_V0.5960.29
109_M307_G0.5950.29
232_R236_R0.5950.29
401_M548_K0.5920.28
585_L631_D0.5920.28
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25_A66_Q0.5910.28
35_T69_G0.5900.28
80_T87_D0.5900.28
524_A531_S0.5890.28
650_R697_R0.5890.28
701_D705_R0.5890.28
19_E499_V0.5880.28
97_G101_F0.5880.28
506_G537_I0.5870.28
374_S378_M0.5860.28
79_M154_I0.5860.28
491_T584_R0.5860.28
146_F246_A0.5860.28
526_M530_T0.5850.28
214_M556_T0.5840.28
539_G543_F0.5840.28
486_N597_R0.5830.28
481_S489_Y0.5830.28
407_L621_L0.5830.28
38_T443_E0.5820.28
368_I371_S0.5820.28
283_S651_V0.5820.28
567_S575_A0.5800.28
32_H136_A0.5800.28
475_Q585_L0.5800.28
462_P648_R0.5790.27
565_T621_L0.5780.27
572_P691_T0.5780.27
258_P262_D0.5780.27
643_E673_I0.5770.27
524_A530_T0.5760.27
129_T136_A0.5750.27
615_I651_V0.5750.27
60_D97_G0.5730.27
418_D444_V0.5720.27
92_L122_V0.5720.27
144_T374_S0.5720.27
199_G252_M0.5720.27
55_Q109_M0.5710.27
73_D672_M0.5700.27
341_I679_I0.5700.27
215_P255_E0.5700.27
221_G226_D0.5700.27
48_I56_Q0.5700.27
698_V703_L0.5690.27
573_L615_I0.5690.27
524_A527_D0.5690.27
502_E506_G0.5690.27
84_E560_V0.5680.27
105_V258_P0.5670.27
585_L651_V0.5670.27
59_M436_G0.5660.27
105_V135_Q0.5650.27
65_E438_G0.5650.27
53_A71_T0.5650.27
25_A37_L0.5640.26
105_V125_A0.5630.26
553_L663_V0.5630.26
262_D351_D0.5630.26
131_T134_R0.5620.26
42_L58_A0.5620.26
106_T139_E0.5620.26
432_H675_F0.5610.26
493_E542_I0.5610.26
588_A648_R0.5610.26
171_V338_S0.5610.26
262_D375_N0.5610.26
573_L619_I0.5600.26
27_A30_V0.5600.26
70_I100_D0.5590.26
409_E412_R0.5580.26
585_L607_R0.5580.26
315_F423_I0.5580.26
130_E147_I0.5580.26
637_M661_M0.5570.26
319_L409_E0.5570.26
508_V517_R0.5560.26
163_E637_M0.5560.26
333_K655_Y0.5550.26
672_M691_T0.5550.26
297_V312_G0.5550.26
306_A347_R0.5550.26
481_S484_R0.5540.26
493_E586_H0.5540.26
39_D79_M0.5530.26
505_L560_V0.5530.26
115_A683_T0.5530.26
59_M77_V0.5520.26
43_A53_A0.5510.26
394_K564_L0.5490.26
203_F214_M0.5490.26
114_G363_G0.5490.26
523_E529_E0.5490.26
603_I608_D0.5480.25
483_N541_N0.5480.25
105_V114_G0.5470.25
216_S381_F0.5470.25
71_T76_N0.5470.25
353_V459_T0.5470.25
236_R239_L0.5460.25
450_E459_T0.5460.25
667_A695_G0.5460.25
204_G318_T0.5450.25
68_R99_V0.5450.25
150_V247_D0.5440.25
456_P490_I0.5440.25
631_D670_D0.5440.25
653_D661_M0.5430.25
39_D58_A0.5430.25
95_T105_V0.5420.25
417_E448_R0.5410.25
425_I674_G0.5390.25
480_V587_D0.5390.25
72_I75_A0.5380.25
45_A79_M0.5380.25
700_A704_Q0.5380.25
39_D73_D0.5380.25
215_P560_V0.5380.25
106_T110_R0.5380.25
32_H53_A0.5370.25
198_D376_E0.5360.25
166_E170_S0.5360.25
289_E361_V0.5350.25
64_D68_R0.5350.25
120_D123_E0.5340.25
280_I364_L0.5340.25
29_H105_V0.5340.25
108_A621_L0.5340.25
393_T466_Y0.5320.25
572_P609_A0.5320.25
108_A695_G0.5310.24
319_L396_I0.5310.24
144_T202_A0.5290.24
75_A698_V0.5290.24
438_G685_G0.5290.24
89_L139_E0.5290.24
130_E679_I0.5280.24
39_D101_F0.5280.24
451_R454_G0.5270.24
495_L545_D0.5270.24
32_H41_L0.5270.24
248_V257_F0.5270.24
502_E520_V0.5260.24
373_V414_V0.5260.24
525_G528_K0.5260.24
122_V663_V0.5250.24
358_I411_L0.5250.24
36_T357_N0.5240.24
462_P469_T0.5240.24
481_S549_G0.5240.24
319_L324_E0.5230.24
123_E153_L0.5220.24
25_A46_G0.5220.24
339_V629_R0.5210.24
480_V485_H0.5210.24
27_A56_Q0.5210.24
277_D291_G0.5200.24
525_G529_E0.5200.24
219_R285_R0.5180.24
74_A298_T0.5180.24
35_T595_I0.5180.24
521_L531_S0.5180.24
481_S485_H0.5170.24
61_T127_P0.5170.24
88_H679_I0.5170.24
454_G651_V0.5170.24
518_R585_L0.5160.24
151_D438_G0.5160.24
22_R33_G0.5160.24
60_D438_G0.5160.24
214_M219_R0.5150.24
319_L339_V0.5150.24
116_L257_F0.5140.23
59_M66_Q0.5140.23
75_A107_R0.5130.23
440_L444_V0.5120.23
29_H42_L0.5120.23
111_A440_L0.5120.23
115_A625_I0.5120.23
120_D152_R0.5120.23
183_T456_P0.5120.23
359_A364_L0.5110.23
507_E511_D0.5110.23
29_H149_K0.5110.23
277_D280_I0.5110.23
213_S222_M0.5110.23
94_D100_D0.5100.23
116_L662_V0.5090.23
374_S398_A0.5090.23
403_D637_M0.5090.23
567_S580_G0.5080.23
110_R467_R0.5080.23
510_M518_R0.5080.23
42_L284_M0.5080.23
590_L698_V0.5080.23
542_I697_R0.5080.23
141_V422_S0.5070.23
560_V602_V0.5070.23
167_R249_V0.5070.23
128_Q315_F0.5060.23
69_G632_V0.5060.23
65_E94_D0.5050.23
100_D132_V0.5050.23
87_D117_V0.5040.23
466_Y696_F0.5040.23
21_I455_I0.5040.23
254_A376_E0.5040.23
68_R78_S0.5040.23
92_L95_T0.5040.23
130_E686_R0.5030.23
105_V418_D0.5030.23
630_I649_G0.5020.23
163_E544_I0.5010.23
98_H113_D0.5010.23
21_I385_D0.5010.23
221_G326_Y0.5010.23
74_A77_V0.5000.23
207_L388_S0.5000.23
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4w224 1 0.9918 100 0.274 Contact Map
1n0uA 1 0.9602 100 0.284 Contact Map
4kiyV 1 0.886 100 0.376 Contact Map
1darA 1 0.7898 100 0.382 Contact Map
2xexA 1 0.8736 100 0.383 Contact Map
4fn5A 1 0.8599 100 0.392 Contact Map
2dy1A 1 0.8516 100 0.424 Contact Map
3j25A 1 0.8516 100 0.441 Contact Map
4zciA 1 0.6415 100 0.571 Contact Map
2yweA 1 0.6497 100 0.571 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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