Q9HHY3 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HHY3 - Vng6171h

UniProt:	Q9HHY3	Sequences: MTSEETQPCCKIVRVADDYDISEIDAKLIERRDHGDSLRDLATYLNKQILSESLNTGTREVVGDADSIYNVLRGDDVNRSRQVELRSKLDRNGIDVEAVERDFVSHQTVRNHLHDCKAIDTGRKSTVDVDDAQKTIEWAQARSEGVIEQTIERLRNAGNVSDTPAEITLSVRVGCSACGRTYRIGEFLEQRGCDCQTDAK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	200 (191)
Sequences:	107 (79)
Seq/√Len:	5.7

HALSA - Q9HHY3 F2Z6F3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
112_H	117_K	3.972	0.93
106_H	110_R	3.469	0.86
112_H	116_C	3.228	0.81
67_S	71_V	3.201	0.81
10_C	112_H	2.780	0.70
25_D	117_K	2.729	0.69
25_D	112_H	2.717	0.68
64_D	67_S	2.677	0.67
45_L	109_V	2.400	0.58
10_C	117_K	2.381	0.58
63_G	67_S	2.329	0.56
108_T	112_H	2.158	0.50
10_C	25_D	2.137	0.49
49_I	106_H	2.108	0.48
15_V	49_I	2.075	0.47
40_D	192_G	2.064	0.47
64_D	70_N	2.013	0.45
140_Q	191_R	1.995	0.44
54_L	58_T	1.983	0.44
80_S	119_I	1.979	0.44
175_C	178_C	1.974	0.44
106_H	114_H	1.973	0.43
10_C	116_C	1.964	0.43
163_T	177_A	1.838	0.39
182_Y	194_D	1.777	0.37
31_R	36_D	1.752	0.36
108_T	117_K	1.747	0.36
21_I	49_I	1.716	0.35
25_D	108_T	1.657	0.33
64_D	71_V	1.654	0.33
99_V	108_T	1.647	0.33
144_E	151_I	1.610	0.32
136_I	188_L	1.596	0.31
96_V	161_S	1.557	0.30
63_G	71_V	1.551	0.30
51_S	189_E	1.546	0.30
73_R	187_F	1.530	0.29
24_I	122_G	1.520	0.29
61_V	85_L	1.513	0.29
100_E	111_N	1.492	0.28
12_I	16_A	1.480	0.28
165_A	188_L	1.463	0.27
37_S	107_Q	1.451	0.27
109_V	143_S	1.430	0.27
29_I	45_L	1.429	0.27
99_V	150_T	1.423	0.26
61_V	136_I	1.412	0.26
30_E	186_E	1.412	0.26
47_K	66_D	1.406	0.26
108_T	116_C	1.381	0.25
67_S	70_N	1.380	0.25
31_R	40_D	1.367	0.25
86_R	119_I	1.362	0.25
8_P	137_E	1.343	0.24
114_H	120_D	1.342	0.24
147_I	183_R	1.330	0.24
26_A	151_I	1.303	0.23
25_D	116_C	1.282	0.23
135_T	172_R	1.279	0.23
86_R	109_V	1.269	0.22
99_V	112_H	1.257	0.22
16_A	109_V	1.249	0.22
178_C	195_C	1.248	0.22
59_R	118_A	1.229	0.21
70_N	100_E	1.220	0.21
63_G	70_N	1.210	0.21
106_H	111_N	1.198	0.21
20_D	56_T	1.190	0.21
50_L	103_F	1.186	0.20
43_T	120_D	1.179	0.20
168_T	181_T	1.174	0.20
97_E	158_G	1.168	0.20
50_L	143_S	1.142	0.20
105_S	109_V	1.141	0.19
178_C	193_C	1.138	0.19
10_C	108_T	1.117	0.19
175_C	195_C	1.108	0.19
28_L	105_S	1.093	0.18
70_N	77_V	1.086	0.18
29_I	117_K	1.084	0.18
26_A	29_I	1.078	0.18
49_I	53_S	1.076	0.18
60_E	171_V	1.066	0.18
151_I	177_A	1.062	0.18
112_H	138_W	1.056	0.18
49_I	143_S	1.044	0.17
49_I	102_D	1.042	0.17
119_I	147_I	1.041	0.17
148_E	162_D	1.029	0.17
166_E	176_S	1.026	0.17
171_V	180_R	1.023	0.17
25_D	99_V	1.021	0.17
13_V	88_K	1.012	0.17
175_C	193_C	1.010	0.17
110_R	166_E	1.004	0.17
152_E	196_Q	1.000	0.17
90_D	187_F	0.981	0.16
78_N	91_R	0.980	0.16
16_A	29_I	0.977	0.16
36_D	105_S	0.971	0.16
71_V	85_L	0.968	0.16
147_I	176_S	0.967	0.16
16_A	111_N	0.961	0.16
15_V	186_E	0.960	0.16
39_R	72_L	0.959	0.16
22_S	66_D	0.958	0.16
63_G	105_S	0.951	0.16
136_I	149_Q	0.949	0.16
71_V	105_S	0.944	0.16
33_D	181_T	0.938	0.15
70_N	74_G	0.937	0.15
23_E	49_I	0.929	0.15
83_V	99_V	0.922	0.15
97_E	189_E	0.918	0.15
66_D	122_G	0.915	0.15
137_E	189_E	0.905	0.15
47_K	77_V	0.904	0.15
53_S	158_G	0.901	0.15
64_D	85_L	0.899	0.15
45_L	111_N	0.897	0.15
17_D	20_D	0.894	0.15
32_R	121_T	0.892	0.15
131_D	159_N	0.891	0.15
71_V	84_E	0.877	0.14
94_I	147_I	0.873	0.14
60_E	118_A	0.869	0.14
99_V	117_K	0.866	0.14
94_I	101_R	0.864	0.14
17_D	23_E	0.863	0.14
37_S	142_R	0.855	0.14
21_I	82_Q	0.854	0.14
21_I	139_A	0.849	0.14
140_Q	144_E	0.848	0.14
128_D	136_I	0.838	0.14
94_I	174_G	0.835	0.14
105_S	116_C	0.835	0.14
118_A	155_R	0.832	0.14
54_L	146_V	0.831	0.14
92_N	189_E	0.827	0.14
22_S	91_R	0.825	0.13
37_S	187_F	0.824	0.13
15_V	102_D	0.819	0.13
66_D	73_R	0.814	0.13
93_G	134_K	0.808	0.13
82_Q	152_E	0.808	0.13
29_I	112_H	0.805	0.13
106_H	145_G	0.803	0.13
16_A	21_I	0.800	0.13
140_Q	163_T	0.800	0.13
135_T	153_R	0.799	0.13
85_L	119_I	0.799	0.13
19_Y	148_E	0.798	0.13
49_I	52_E	0.797	0.13
22_S	51_S	0.791	0.13
90_D	130_D	0.786	0.13
49_I	118_A	0.779	0.13
100_E	153_R	0.779	0.13
131_D	136_I	0.779	0.13
20_D	62_V	0.775	0.13
80_S	84_E	0.775	0.13
107_Q	142_R	0.774	0.13
155_R	159_N	0.773	0.13
15_V	29_I	0.772	0.13
38_L	95_D	0.771	0.13
101_R	119_I	0.770	0.13
128_D	162_D	0.768	0.13
42_A	192_G	0.768	0.13
84_E	120_D	0.763	0.13
110_R	135_T	0.763	0.13
37_S	146_V	0.757	0.12
13_V	106_H	0.755	0.12
77_V	167_I	0.753	0.12
120_D	145_G	0.751	0.12
48_Q	71_V	0.745	0.12
13_V	110_R	0.744	0.12
19_Y	56_T	0.741	0.12
12_I	29_I	0.730	0.12
66_D	77_V	0.725	0.12
102_D	115_D	0.719	0.12
77_V	80_S	0.718	0.12
54_L	64_D	0.716	0.12
35_G	121_T	0.715	0.12
104_V	111_N	0.710	0.12
114_H	121_T	0.708	0.12
149_Q	190_Q	0.708	0.12
56_T	87_S	0.707	0.12
101_R	160_V	0.698	0.12
10_C	138_W	0.696	0.12
30_E	35_G	0.694	0.12
152_E	186_E	0.691	0.11
70_N	75_D	0.688	0.11
38_L	179_G	0.688	0.11
66_D	103_F	0.688	0.11
27_K	161_S	0.685	0.11
16_A	115_D	0.684	0.11
70_N	159_N	0.681	0.11
42_A	106_H	0.681	0.11
131_D	160_V	0.676	0.11
140_Q	151_I	0.675	0.11
98_A	180_R	0.675	0.11
38_L	117_K	0.672	0.11
30_E	133_Q	0.671	0.11
26_A	179_G	0.671	0.11
29_I	119_I	0.669	0.11
83_V	170_S	0.669	0.11
50_L	179_G	0.668	0.11
74_G	77_V	0.664	0.11
151_I	160_V	0.660	0.11
7_Q	117_K	0.657	0.11
10_C	137_E	0.649	0.11
98_A	196_Q	0.648	0.11
28_L	113_L	0.646	0.11
69_Y	103_F	0.644	0.11
34_H	151_I	0.641	0.11
66_D	169_L	0.639	0.11
62_V	98_A	0.638	0.11
57_G	168_T	0.635	0.11
120_D	147_I	0.628	0.11
105_S	141_A	0.628	0.11
131_D	157_A	0.626	0.11
37_S	192_G	0.626	0.11
32_R	45_L	0.625	0.11
33_D	156_N	0.625	0.11
71_V	153_R	0.623	0.11
52_E	163_T	0.622	0.11
55_N	135_T	0.619	0.10
6_T	62_V	0.617	0.10
120_D	162_D	0.615	0.10
44_Y	159_N	0.613	0.10
12_I	160_V	0.610	0.10
76_D	158_G	0.605	0.10
79_R	114_H	0.605	0.10
52_E	167_I	0.600	0.10
76_D	97_E	0.598	0.10
81_R	188_L	0.595	0.10
78_N	94_I	0.594	0.10
145_G	153_R	0.591	0.10
86_R	146_V	0.584	0.10
123_R	189_E	0.582	0.10
15_V	23_E	0.581	0.10
53_S	142_R	0.581	0.10
151_I	196_Q	0.581	0.10
142_R	146_V	0.573	0.10
184_I	188_L	0.573	0.10
32_R	120_D	0.571	0.10
163_T	171_V	0.570	0.10
61_V	135_T	0.569	0.10
110_R	114_H	0.568	0.10
102_D	192_G	0.564	0.10
47_K	187_F	0.564	0.10
86_R	100_E	0.560	0.10
38_L	108_T	0.559	0.10
78_N	143_S	0.557	0.10
112_H	174_G	0.557	0.10
60_E	160_V	0.557	0.10
39_R	163_T	0.555	0.10
7_Q	112_H	0.553	0.10
118_A	130_D	0.552	0.10
42_A	91_R	0.551	0.10
51_S	94_I	0.549	0.10
15_V	99_V	0.547	0.10
136_I	146_V	0.546	0.10
98_A	101_R	0.538	0.09
177_A	196_Q	0.538	0.09
23_E	117_K	0.534	0.09
78_N	167_I	0.533	0.09
33_D	103_F	0.529	0.09
78_N	134_K	0.525	0.09
76_D	104_V	0.522	0.09
13_V	29_I	0.518	0.09
103_F	168_T	0.517	0.09
14_R	142_R	0.515	0.09
108_T	184_I	0.515	0.09
112_H	141_A	0.512	0.09
25_D	170_S	0.510	0.09
62_V	94_I	0.510	0.09
162_D	165_A	0.508	0.09
96_V	99_V	0.508	0.09
44_Y	56_T	0.508	0.09
121_T	131_D	0.507	0.09
60_E	164_P	0.507	0.09
62_V	70_N	0.504	0.09
140_Q	160_V	0.501	0.09
23_E	52_E	0.500	0.09
123_R	159_N	0.500	0.09
35_G	119_I	0.500	0.09

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2v0cA	1	0.815	29	0.959	Contact Map
2lvsA	1	0.48	28.7	0.959	Contact Map
1e5xA	2	0.255	26.7	0.96	Contact Map
3wwlA	1	0.145	23.5	0.961	Contact Map
3u31A	1	0.69	23.5	0.961	Contact Map
4l5eA	2	0.225	23.3	0.961	Contact Map
2kgoA	1	0.315	22.3	0.961	Contact Map
1pdnC	1	0.51	22.1	0.961	Contact Map
3h99A	1	0.72	21.1	0.962	Contact Map
1q14A	3	0.705	18.1	0.963	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0072 seconds.