Q9HHW5 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HHW5 - Sodium-dependent phosphate transporter

UniProt:	Q9HHW5	Sequences: MALSVVFVVGVAAAIFVGVNIGGSSTGVAFGPATGSDALSMRQASGLMAVFVLLGGFTIGTNVVDALGADFIPAEYFTLGASIGVLLFIGLGILIGNVLNVSTSTSQTAVAAVVAMGAALGVLDWRTVGVVGMWWVLSTTLAFWICAFVGRYFYDAIVNLLSFESDDTGRFAELVVIGIGCYMGFSTGASNVASAVAPLVGSRQLEMTSGVAIGGVAIGVGAFAIGPRTMETVGEDITDLSLEASPDR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	248 (238)
Sequences:	2767 (1469)
Seq/√Len:	95.2

ECOLI - PITA PITB
BACSU - PIT SULP
HALSA - Q9HHW5 Q9HRD0 O54523 Q9HN03 Q9HHS6
SULSO - Q97VZ0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
40_S	43_Q	4.898	1.00
19_V	224_A	3.935	1.00
132_G	136_V	3.484	1.00
133_M	137_L	3.092	1.00
127_T	130_V	3.069	1.00
81_A	116_M	3.068	1.00
229_T	232_T	2.917	1.00
47_L	181_C	2.912	1.00
148_F	152_Y	2.700	1.00
114_V	128_V	2.658	1.00
46_G	50_V	2.656	1.00
72_I	117_G	2.428	1.00
95_I	99_L	2.393	1.00
53_L	216_V	2.382	1.00
15_I	217_A	2.360	1.00
15_I	213_I	2.349	1.00
10_G	202_S	2.346	1.00
203_R	210_G	2.339	1.00
30_F	34_T	2.290	1.00
91_L	95_I	2.279	1.00
24_S	96_G	2.269	1.00
21_I	105_T	2.189	1.00
65_D	69_A	2.095	1.00
97_N	229_T	2.094	1.00
54_L	185_F	1.999	1.00
97_N	103_T	1.978	1.00
8_V	12_A	1.967	1.00
25_S	28_V	1.958	1.00
45_S	223_F	1.951	1.00
96_G	103_T	1.944	1.00
175_V	246_P	1.864	1.00
39_L	177_I	1.834	1.00
57_F	208_T	1.831	1.00
186_S	190_S	1.807	1.00
220_V	224_A	1.784	1.00
33_A	180_G	1.779	1.00
29_A	183_M	1.775	1.00
137_L	141_L	1.747	1.00
93_I	105_T	1.722	1.00
52_V	222_A	1.670	1.00
129_G	133_M	1.655	1.00
24_S	229_T	1.629	1.00
51_F	181_C	1.605	1.00
20_N	94_L	1.598	1.00
52_V	187_T	1.596	1.00
219_G	222_A	1.596	1.00
172_A	246_P	1.593	1.00
190_S	194_S	1.583	1.00
24_S	97_N	1.558	1.00
118_A	122_V	1.557	1.00
34_T	44_A	1.556	1.00
124_D	127_T	1.529	1.00
55_G	215_G	1.499	1.00
73_P	76_Y	1.492	1.00
13_A	83_I	1.477	1.00
170_R	174_L	1.467	1.00
45_S	49_A	1.460	1.00
241_S	244_A	1.440	1.00
175_V	178_G	1.423	0.99
24_S	103_T	1.416	0.99
37_D	235_E	1.415	0.99
18_G	217_A	1.415	0.99
183_M	240_L	1.411	0.99
54_L	58_T	1.408	0.99
24_S	93_I	1.403	0.99
155_D	158_V	1.402	0.99
53_L	219_G	1.400	0.99
48_M	222_A	1.392	0.99
6_V	83_I	1.386	0.99
152_Y	156_A	1.381	0.99
151_R	155_D	1.368	0.99
85_V	109_A	1.368	0.99
112_A	116_M	1.365	0.99
56_G	60_G	1.349	0.99
147_A	151_R	1.339	0.99
91_L	220_V	1.337	0.99
167_D	170_R	1.327	0.99
110_V	131_V	1.327	0.99
16_F	94_L	1.287	0.99
10_G	83_I	1.264	0.99
7_F	206_E	1.264	0.99
48_M	184_G	1.257	0.99
233_V	237_I	1.226	0.98
12_A	16_F	1.218	0.98
157_I	160_L	1.216	0.98
231_E	236_D	1.215	0.98
24_S	105_T	1.194	0.98
170_R	173_E	1.191	0.98
191_N	194_S	1.187	0.98
153_F	157_I	1.187	0.98
135_W	139_T	1.186	0.98
65_D	68_G	1.177	0.98
17_V	89_I	1.175	0.98
16_F	20_N	1.175	0.98
187_T	191_N	1.163	0.98
192_V	214_G	1.161	0.98
60_G	211_V	1.158	0.98
85_V	113_V	1.153	0.98
79_L	202_S	1.149	0.98
49_A	219_G	1.146	0.98
68_G	106_S	1.144	0.98
63_V	125_W	1.144	0.98
89_I	114_V	1.137	0.98
93_I	97_N	1.129	0.97
180_G	184_G	1.127	0.97
199_L	214_G	1.095	0.97
230_M	237_I	1.077	0.97
152_Y	155_D	1.070	0.96
103_T	229_T	1.068	0.96
123_L	128_V	1.065	0.96
29_A	33_A	1.065	0.96
231_E	235_E	1.056	0.96
80_G	84_G	1.042	0.96
43_Q	46_G	1.037	0.96
176_V	179_I	1.029	0.96
196_V	214_G	1.026	0.95
192_V	218_I	1.023	0.95
88_F	112_A	1.020	0.95
85_V	112_A	1.015	0.95
134_W	138_S	0.990	0.94
29_A	245_S	0.987	0.94
86_L	185_F	0.986	0.94
174_L	178_G	0.973	0.94
84_G	88_F	0.972	0.94
19_V	94_L	0.965	0.94
16_F	90_G	0.962	0.94
238_T	241_S	0.959	0.93
23_G	97_N	0.954	0.93
131_V	134_W	0.936	0.93
111_A	115_A	0.934	0.93
223_F	230_M	0.933	0.93
49_A	184_G	0.932	0.93
214_G	218_I	0.931	0.92
227_P	231_E	0.928	0.92
238_T	244_A	0.924	0.92
62_N	65_D	0.923	0.92
42_R	46_G	0.923	0.92
57_F	215_G	0.922	0.92
92_G	107_Q	0.921	0.92
93_I	96_G	0.918	0.92
53_L	57_F	0.915	0.92
169_G	173_E	0.911	0.92
61_T	211_V	0.904	0.91
31_G	225_I	0.901	0.91
30_F	47_L	0.898	0.91
190_S	197_A	0.890	0.91
181_C	184_G	0.887	0.91
33_A	39_L	0.886	0.90
180_G	183_M	0.885	0.90
6_V	141_L	0.883	0.90
33_A	47_L	0.881	0.90
91_L	99_L	0.877	0.90
118_A	148_F	0.867	0.90
85_V	89_I	0.864	0.89
93_I	103_T	0.860	0.89
163_F	168_T	0.859	0.89
63_V	66_A	0.859	0.89
46_G	155_D	0.857	0.89
211_V	215_G	0.857	0.89
176_V	187_T	0.852	0.89
96_G	111_A	0.838	0.88
56_G	215_G	0.832	0.88
147_A	184_G	0.830	0.87
58_T	185_F	0.829	0.87
114_V	123_L	0.826	0.87
96_G	105_T	0.823	0.87
89_I	105_T	0.823	0.87
11_V	15_I	0.822	0.87
33_A	38_A	0.817	0.87
70_D	123_L	0.809	0.86
184_G	187_T	0.808	0.86
208_T	212_A	0.804	0.86
184_G	197_A	0.798	0.85
176_V	226_G	0.794	0.85
134_W	189_A	0.790	0.85
68_G	204_Q	0.790	0.85
70_D	73_P	0.789	0.85
47_L	51_F	0.789	0.85
19_V	225_I	0.787	0.84
38_A	173_E	0.784	0.84
7_F	85_V	0.776	0.84
180_G	187_T	0.776	0.84
196_V	199_L	0.774	0.83
101_V	110_V	0.770	0.83
28_V	52_V	0.768	0.83
47_L	55_G	0.767	0.83
52_V	107_Q	0.766	0.83
67_L	197_A	0.765	0.83
225_I	228_R	0.764	0.83
176_V	245_S	0.764	0.83
125_W	129_G	0.764	0.83
107_Q	187_T	0.760	0.82
89_I	139_T	0.759	0.82
68_G	82_S	0.753	0.82
213_I	220_V	0.752	0.82
9_V	133_M	0.752	0.82
39_L	43_Q	0.747	0.81
85_V	116_M	0.746	0.81
36_S	106_S	0.738	0.80
37_D	40_S	0.733	0.80
183_M	193_A	0.732	0.80
20_N	93_I	0.728	0.80
18_G	23_G	0.717	0.79
9_V	80_G	0.715	0.78
12_A	140_T	0.713	0.78
23_G	105_T	0.705	0.77
186_S	189_A	0.702	0.77
48_M	52_V	0.701	0.77
26_T	222_A	0.690	0.76
176_V	242_L	0.689	0.76
11_V	88_F	0.688	0.76
129_G	132_G	0.687	0.76
200_V	210_G	0.672	0.74
189_A	202_S	0.670	0.74
100_N	112_A	0.666	0.73
160_L	168_T	0.665	0.73
177_I	190_S	0.659	0.72
73_P	95_I	0.658	0.72
36_S	52_V	0.656	0.72
5_V	126_R	0.650	0.71
147_A	235_E	0.650	0.71
49_A	223_F	0.649	0.71
235_E	239_D	0.648	0.71
54_L	76_Y	0.648	0.71
132_G	163_F	0.647	0.71
9_V	203_R	0.640	0.70
58_T	62_N	0.638	0.70
103_T	108_T	0.636	0.70
170_R	178_G	0.636	0.70
28_V	34_T	0.630	0.69
97_N	228_R	0.630	0.69
9_V	98_V	0.630	0.69
56_G	192_V	0.630	0.69
60_G	117_G	0.628	0.69
23_G	96_G	0.626	0.69
240_L	244_A	0.625	0.68
140_T	144_W	0.624	0.68
155_D	159_N	0.621	0.68
123_L	152_Y	0.618	0.68
129_G	170_R	0.617	0.67
241_S	245_S	0.617	0.67
54_L	129_G	0.616	0.67
152_Y	158_V	0.615	0.67
76_Y	147_A	0.615	0.67
7_F	76_Y	0.614	0.67
20_N	91_L	0.606	0.66
79_L	205_L	0.606	0.66
140_T	145_I	0.606	0.66
114_V	119_A	0.605	0.66
17_V	105_T	0.605	0.66
130_V	160_L	0.604	0.66
71_F	85_V	0.604	0.66
214_G	217_A	0.601	0.65
169_G	241_S	0.600	0.65
28_V	187_T	0.599	0.65
148_F	162_S	0.598	0.65
18_G	26_T	0.598	0.65
186_S	191_N	0.595	0.65
12_A	208_T	0.594	0.65
132_G	138_S	0.594	0.65
8_V	137_L	0.593	0.64
76_Y	113_V	0.592	0.64
144_W	148_F	0.592	0.64
92_G	97_N	0.590	0.64
57_F	211_V	0.589	0.64
27_G	139_T	0.586	0.64
109_A	112_A	0.586	0.64
150_G	244_A	0.585	0.63
7_F	11_V	0.585	0.63
67_L	110_V	0.584	0.63
47_L	184_G	0.583	0.63
204_Q	207_M	0.583	0.63
107_Q	111_A	0.580	0.63
34_T	230_M	0.579	0.63
195_A	214_G	0.575	0.62
141_L	158_V	0.575	0.62
18_G	90_G	0.574	0.62
151_R	154_Y	0.573	0.62
57_F	212_A	0.572	0.62
135_W	143_F	0.571	0.62
193_A	196_V	0.571	0.62
176_V	188_G	0.570	0.61
138_S	142_A	0.567	0.61
42_R	156_A	0.566	0.61
26_T	218_I	0.565	0.61
116_M	119_A	0.565	0.61
136_V	144_W	0.561	0.60
50_V	129_G	0.560	0.60
45_S	71_F	0.560	0.60
101_V	106_S	0.559	0.60
35_G	238_T	0.559	0.60
215_G	218_I	0.557	0.60
179_I	183_M	0.557	0.60
192_V	198_P	0.556	0.59
62_N	72_I	0.556	0.59
60_G	200_V	0.555	0.59
40_S	160_L	0.555	0.59
191_N	197_A	0.554	0.59
191_N	226_G	0.553	0.59
151_R	178_G	0.553	0.59
224_A	227_P	0.551	0.59
114_V	220_V	0.551	0.59
62_N	131_V	0.549	0.59
28_V	37_D	0.549	0.59
149_V	178_G	0.547	0.58
154_Y	243_E	0.547	0.58
194_S	198_P	0.543	0.58
185_F	199_L	0.543	0.58
190_S	238_T	0.543	0.58
83_I	147_A	0.542	0.58
92_G	96_G	0.541	0.57
193_A	225_I	0.540	0.57
148_F	153_F	0.538	0.57
28_V	67_L	0.536	0.57
141_L	148_F	0.536	0.57
12_A	76_Y	0.535	0.57
132_G	151_R	0.535	0.57
5_V	170_R	0.535	0.57
62_N	70_D	0.531	0.56
26_T	177_I	0.531	0.56
12_A	78_T	0.527	0.55
143_F	199_L	0.526	0.55
90_G	197_A	0.524	0.55
11_V	199_L	0.523	0.55
25_S	107_Q	0.521	0.55
213_I	217_A	0.521	0.55
79_L	153_F	0.519	0.54
146_C	150_G	0.519	0.54
146_C	157_I	0.518	0.54
169_G	174_L	0.516	0.54
125_W	200_V	0.514	0.54
33_A	177_I	0.513	0.54
47_L	202_S	0.512	0.53
87_L	144_W	0.512	0.53
80_G	132_G	0.511	0.53
98_V	141_L	0.510	0.53
194_S	201_G	0.510	0.53
84_G	191_N	0.510	0.53
6_V	87_L	0.510	0.53
200_V	204_Q	0.509	0.53
51_F	60_G	0.509	0.53
25_S	191_N	0.509	0.53
64_V	105_T	0.508	0.53
27_G	131_V	0.508	0.53
37_D	122_V	0.508	0.53
27_G	100_N	0.508	0.53
148_F	161_L	0.508	0.53
145_I	149_V	0.506	0.53
226_G	229_T	0.506	0.53
169_G	243_E	0.504	0.52
95_I	136_V	0.504	0.52
8_V	11_V	0.504	0.52
41_M	227_P	0.504	0.52
208_T	211_V	0.502	0.52
171_F	175_V	0.501	0.52
192_V	196_V	0.501	0.52
128_V	142_A	0.500	0.52

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3b5dA	2	0.3831	9	0.961	Contact Map
2wscI	1	0.121	7.6	0.963	Contact Map
3zojA	3	0.621	6.5	0.964	Contact Map
4l6vi	1	0.1532	5.7	0.965	Contact Map
1jb0I	1	0.1532	5.7	0.965	Contact Map
4xk8I	1	0.1169	5	0.966	Contact Map
3qe7A	2	0.6129	4.8	0.966	Contact Map
3gd8A	4	0.5565	4.6	0.966	Contact Map
4wgvA	2	0.5363	3.9	0.968	Contact Map
2kv5A	1	0.1331	3.7	0.968	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0083 seconds.