GREMLIN Database
Q9HHW2 - Cell division cycle protein
UniProt: Q9HHW2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 737 (569)
Sequences: 134 (74)
Seq/√Len: 3.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
536_L671_V3.6020.65
530_S533_G3.4450.61
631_V687_V3.2430.56
483_Q511_T3.1300.53
517_A527_N3.1240.53
511_T538_N2.9560.49
525_N608_I2.8830.47
465_W500_A2.8240.46
641_R667_T2.8080.45
548_V607_V2.8060.45
219_F223_G2.6310.41
667_T675_I2.5850.40
539_K590_S2.4870.37
160_Q165_I2.4680.37
155_G159_V2.4510.36
577_Q585_G2.4130.35
542_G575_R2.3670.34
481_T500_A2.3440.34
557_E670_Y2.3050.33
219_F222_L2.2980.33
539_K636_P2.2700.32
468_V608_I2.2330.31
168_A171_S2.1920.31
469_G528_F2.1870.30
474_A491_A2.1720.30
467_H651_D2.1710.30
346_L654_L2.1700.30
635_E670_Y2.1480.30
536_L596_L2.1420.29
482_V491_A2.1250.29
687_V691_V2.0730.28
590_S636_P2.0640.28
166_E170_Q2.0560.28
629_R684_T2.0390.27
491_A676_E2.0240.27
289_I333_I2.0190.27
596_L671_V2.0030.27
527_N678_V1.9760.26
636_P641_R1.9560.26
279_F609_A1.9530.26
440_D631_V1.9510.26
511_T571_I1.9510.26
612_N633_V1.9300.25
475_K711_H1.9170.25
257_T265_S1.9100.25
207_E663_L1.8840.24
263_I655_A1.8790.24
546_R563_V1.8730.24
162_T166_E1.8580.24
645_F675_I1.8500.24
456_V525_N1.8440.24
509_P575_R1.8250.23
654_L659_D1.8150.23
532_K544_S1.8140.23
162_T168_A1.8070.23
596_L669_G1.8000.23
568_I633_V1.7920.23
621_L628_D1.7840.22
406_E558_N1.7830.22
289_I670_Y1.7780.22
508_P536_L1.7740.22
334_G531_I1.7670.22
534_P549_R1.7550.22
154_S164_E1.7530.22
496_A612_N1.7500.22
373_H710_E1.7410.22
162_T167_I1.7400.22
248_A712_F1.7310.22
258_I263_I1.7290.21
361_P527_N1.7190.21
438_E493_E1.7110.21
480_E497_L1.7030.21
470_G540_Y1.6960.21
556_R595_E1.6870.21
186_T388_Y1.6760.21
332_V477_R1.6710.21
482_V551_V1.6710.21
481_T624_P1.6640.20
529_I636_P1.6560.20
612_N734_A1.6540.20
568_I612_N1.6530.20
278_V592_L1.6350.20
573_S586_E1.6220.20
609_A641_R1.6200.20
509_P542_G1.6160.20
453_L456_V1.6160.20
537_F622_L1.6150.20
297_S531_I1.6100.20
468_V723_A1.6090.19
279_F289_I1.6060.19
544_S589_V1.6020.19
492_Y610_T1.5940.19
465_W481_T1.5890.19
484_W518_K1.5720.19
481_T615_D1.5680.19
341_A473_D1.5530.19
529_I539_K1.5520.19
352_F596_L1.5520.19
346_L670_Y1.5510.19
160_Q164_E1.5460.18
492_Y541_V1.5460.18
563_V568_I1.5440.18
620_A636_P1.5410.18
333_I352_F1.5300.18
482_V524_A1.5290.18
497_L671_V1.5280.18
540_Y621_L1.5120.18
540_Y628_D1.5120.18
525_N671_V1.5050.18
440_D726_E1.5020.18
535_E544_S1.4970.18
559_A565_F1.4930.18
500_A615_D1.4890.18
518_K612_N1.4860.18
563_V633_V1.4850.18
637_D724_G1.4820.18
239_G591_Q1.4690.17
539_K568_I1.4670.17
641_R675_I1.4660.17
536_L571_I1.4610.17
159_V164_E1.4560.17
541_V573_S1.4460.17
501_K519_A1.4380.17
552_F555_A1.4360.17
552_F560_P1.4360.17
552_F566_D1.4360.17
555_A560_P1.4360.17
555_A566_D1.4360.17
560_P566_D1.4360.17
606_V617_I1.4360.17
389_A398_A1.4330.17
502_G613_R1.4330.17
592_L715_A1.4320.17
646_E665_E1.4300.17
583_N586_E1.4300.17
228_K294_E1.4250.17
518_K633_V1.4220.17
641_R644_I1.4190.17
468_V525_N1.4180.17
258_I262_E1.4060.16
255_F260_G1.4060.16
562_V670_Y1.4060.16
533_G544_S1.4050.16
530_S535_E1.3970.16
616_L621_L1.3940.16
616_L628_D1.3940.16
160_Q170_Q1.3930.16
535_E589_V1.3910.16
546_R683_A1.3860.16
294_E676_E1.3860.16
489_A511_T1.3840.16
484_W526_S1.3810.16
572_A616_L1.3800.16
180_G199_D1.3790.16
330_L656_E1.3790.16
279_F385_L1.3780.16
541_V549_R1.3720.16
263_I710_E1.3700.16
469_G517_A1.3680.16
563_V612_N1.3630.16
161_N170_Q1.3600.16
394_G585_G1.3560.16
239_G366_R1.3480.16
671_V683_A1.3480.16
487_E680_R1.3480.16
269_G273_E1.3400.16
152_Q164_E1.3400.16
450_P617_I1.3390.16
157_V169_D1.3340.15
159_V165_I1.3290.15
253_A294_E1.3230.15
385_L390_E1.3210.15
388_Y692_R1.3120.15
599_L719_V1.3100.15
164_E167_I1.3030.15
157_V164_E1.3030.15
209_I364_D1.3020.15
156_T164_E1.3010.15
385_L391_N1.3010.15
534_P588_V1.2970.15
237_G478_L1.2960.15
606_V615_D1.2960.15
503_V729_A1.2910.15
471_L504_L1.2880.15
544_S549_R1.2870.15
164_E249_N1.2840.15
529_I669_G1.2760.15
543_E680_R1.2760.15
151_T154_S1.2750.15
596_L599_L1.2740.15
484_W495_V1.2730.15
533_G587_R1.2700.15
489_A508_P1.2690.15
618_D644_I1.2650.15
576_G587_R1.2630.15
569_D647_I1.2610.15
550_E683_A1.2600.14
546_R688_R1.2580.14
535_E549_R1.2580.14
532_K589_V1.2560.14
534_P586_E1.2560.14
295_L607_V1.2530.14
480_E526_S1.2530.14
606_V680_R1.2500.14
551_V715_A1.2470.14
361_P517_A1.2460.14
534_P593_L1.2400.14
702_V714_Q1.2350.14
518_K563_V1.2260.14
155_G160_Q1.2230.14
573_S583_N1.2180.14
239_G593_L1.2170.14
532_K535_E1.2170.14
534_P621_L1.2170.14
534_P628_D1.2170.14
534_P544_S1.2160.14
491_A574_E1.2090.14
567_E575_R1.2080.14
556_R606_V1.2080.14
497_L635_E1.2070.14
486_L551_V1.2010.14
157_V160_Q1.1970.14
395_F491_A1.1950.14
163_T170_Q1.1930.14
153_P165_I1.1930.14
265_S659_D1.1910.14
573_S593_L1.1890.14
522_N679_C1.1880.14
346_L657_D1.1870.14
153_P169_D1.1830.14
468_V669_G1.1800.14
586_E621_L1.1800.14
586_E628_D1.1800.14
534_P584_V1.1770.13
475_K517_A1.1770.13
329_Q337_N1.1710.13
458_V461_P1.1660.13
676_E683_A1.1640.13
568_I590_S1.1630.13
524_A727_T1.1620.13
234_G529_I1.1610.13
617_I680_R1.1590.13
565_F673_A1.1550.13
243_I383_V1.1520.13
508_P592_L1.1510.13
436_V441_F1.1390.13
525_N675_I1.1330.13
163_T168_A1.1320.13
540_Y616_L1.1240.13
458_V467_H1.1230.13
264_M715_A1.1200.13
508_P596_L1.1190.13
453_L539_K1.1190.13
458_V489_A1.1150.13
267_Y343_D1.1140.13
511_T637_D1.1100.13
261_P264_M1.1090.13
151_T157_V1.1050.13
529_I633_V1.1030.13
590_S604_D1.1000.13
571_I617_I1.0990.13
554_K558_N1.0980.13
543_E612_N1.0960.13
495_V524_A1.0920.12
539_K668_D1.0920.12
582_S585_G1.0840.12
532_K621_L1.0830.12
532_K628_D1.0830.12
163_T167_I1.0810.12
344_P436_V1.0810.12
672_G682_A1.0780.12
470_G616_L1.0770.12
281_E288_A1.0650.12
549_R621_L1.0620.12
549_R628_D1.0620.12
406_E583_N1.0620.12
535_E621_L1.0600.12
535_E628_D1.0600.12
152_Q157_V1.0570.12
489_A536_L1.0530.12
384_D659_D1.0530.12
456_V730_F1.0520.12
159_V163_T1.0510.12
574_E676_E1.0500.12
448_I453_L1.0480.12
284_E391_N1.0480.12
393_Q585_G1.0470.12
154_S168_A1.0420.12
576_G721_S1.0420.12
508_P599_L1.0390.12
591_Q621_L1.0380.12
591_Q628_D1.0380.12
474_A631_V1.0360.12
590_S641_R1.0360.12
534_P541_V1.0320.12
586_E593_L1.0290.12
495_V526_S1.0260.12
161_N169_D1.0250.12
209_I708_S1.0250.12
557_E635_E1.0240.12
321_M498_E1.0240.12
476_E715_A1.0230.12
537_F586_E1.0230.12
589_V621_L1.0220.12
589_V628_D1.0220.12
556_R590_S1.0200.12
383_V407_S1.0200.12
216_P222_L1.0200.12
341_A394_G1.0200.12
491_A632_A1.0160.12
567_E610_T1.0140.12
525_N627_L1.0130.12
552_F567_E1.0130.12
555_A567_E1.0130.12
560_P567_E1.0130.12
437_T660_V1.0120.12
537_F604_D1.0120.12
534_P589_V1.0110.12
573_S616_L1.0110.12
544_S621_L1.0070.12
544_S628_D1.0070.12
160_Q163_T1.0060.12
562_V585_G1.0060.12
503_V611_T1.0040.12
468_V675_I1.0020.12
599_L683_A1.0010.12
458_V519_A0.9970.11
489_A596_L0.9960.11
523_E550_E0.9950.11
497_L682_A0.9880.11
475_K503_V0.9880.11
464_T653_P0.9870.11
302_R489_A0.9840.11
715_A730_F0.9820.11
247_V434_I0.9780.11
469_G475_K0.9780.11
526_S733_P0.9770.11
400_L406_E0.9760.11
258_I289_I0.9750.11
165_I168_A0.9710.11
533_G589_V0.9700.11
565_F584_V0.9700.11
192_Y468_V0.9640.11
550_E619_D0.9630.11
157_V168_A0.9620.11
552_F644_I0.9590.11
555_A644_I0.9590.11
560_P644_I0.9590.11
566_D644_I0.9590.11
671_V730_F0.9580.11
606_V681_E0.9580.11
330_L735_E0.9570.11
234_G609_A0.9570.11
518_K522_N0.9560.11
727_T733_P0.9550.11
499_P524_A0.9510.11
517_A528_F0.9510.11
162_T170_Q0.9470.11
160_Q167_I0.9460.11
535_E586_E0.9450.11
551_V687_V0.9440.11
156_T168_A0.9440.11
562_V651_D0.9400.11
590_S620_A0.9380.11
546_R670_Y0.9380.11
491_A523_E0.9380.11
525_N641_R0.9360.11
348_R646_E0.9350.11
449_E629_R0.9340.11
528_F542_G0.9280.11
469_G519_A0.9270.11
534_P573_S0.9240.11
181_E249_N0.9230.11
536_L603_E0.9220.11
621_L625_G0.9220.11
625_G628_D0.9220.11
484_W637_D0.9200.11
484_W497_L0.9180.11
534_P540_Y0.9180.11
225_E460_V0.9160.11
332_V645_F0.9150.11
627_L660_V0.9150.11
568_I582_S0.9140.11
217_E688_R0.9110.11
546_R691_V0.9100.11
492_Y605_I0.9080.11
161_N165_I0.9080.11
482_V518_K0.9050.11
540_Y586_E0.9040.11
627_L723_A0.9040.11
634_D687_V0.9030.11
246_A538_N0.9010.11
158_V164_E0.9000.11
458_V522_N0.8990.10
542_G567_E0.8990.10
572_A621_L0.8990.10
572_A628_D0.8990.10
478_L520_V0.8960.10
558_N561_T0.8950.10
409_M487_E0.8950.10
480_E551_V0.8950.10
541_V616_L0.8940.10
456_V608_I0.8940.10
469_G527_N0.8930.10
374_T473_D0.8930.10
517_A678_V0.8910.10
607_V729_A0.8910.10
362_D473_D0.8890.10
475_K550_E0.8860.10
539_K609_A0.8840.10
608_I730_F0.8840.10
660_V681_E0.8810.10
636_P667_T0.8770.10
482_V632_A0.8740.10
394_G529_I0.8720.10
539_K641_R0.8700.10
631_V647_I0.8670.10
563_V673_A0.8660.10
242_L712_F0.8640.10
154_S157_V0.8630.10
578_G582_S0.8620.10
153_P157_V0.8610.10
501_K652_K0.8590.10
239_G535_E0.8590.10
392_T533_G0.8560.10
680_R684_T0.8560.10
582_S590_S0.8560.10
239_G621_L0.8540.10
239_G628_D0.8540.10
475_K569_D0.8530.10
689_E711_H0.8530.10
551_V574_E0.8530.10
622_L628_D0.8520.10
633_V680_R0.8520.10
163_T186_T0.8520.10
517_A523_E0.8480.10
244_A387_R0.8450.10
609_A667_T0.8420.10
357_E473_D0.8410.10
505_L636_P0.8400.10
489_A571_I0.8390.10
536_L599_L0.8380.10
499_P612_N0.8310.10
556_R680_R0.8310.10
543_E562_V0.8290.10
543_E595_E0.8280.10
649_T679_C0.8280.10
541_V586_E0.8280.10
657_D702_V0.8260.10
535_E593_L0.8250.10
489_A592_L0.8240.10
352_F489_A0.8230.10
534_P591_Q0.8230.10
193_E199_D0.8210.10
630_H730_F0.8190.10
469_G523_E0.8170.10
508_P632_A0.8160.10
522_N729_A0.8160.10
207_E317_L0.8160.10
273_E404_V0.8160.10
594_T602_L0.8150.10
484_W676_E0.8100.10
157_V165_I0.8080.10
282_A343_D0.8050.10
523_E683_A0.8040.10
227_P665_E0.8040.10
396_V465_W0.8030.10
534_P616_L0.8030.10
508_P511_T0.8020.10
523_E648_H0.8010.10
578_G585_G0.8000.10
230_V710_E0.7980.10
174_E203_E0.7980.10
444_A634_D0.7980.10
290_V338_R0.7960.10
261_P657_D0.7960.10
568_I680_R0.7960.10
160_Q166_E0.7960.10
480_E495_V0.7950.10
553_S669_G0.7950.10
247_V631_V0.7940.10
543_E617_I0.7940.10
637_D640_A0.7940.10
364_D374_T0.7930.10
154_S165_I0.7930.10
161_N164_E0.7930.10
164_E170_Q0.7920.10
441_F520_V0.7920.10
484_W733_P0.7910.10
489_A676_E0.7870.09
604_D612_N0.7860.09
577_Q582_S0.7840.09
351_R480_E0.7820.09
615_D624_P0.7810.09
595_E730_F0.7810.09
158_V166_E0.7800.09
686_A707_L0.7800.09
573_S581_D0.7790.09
599_L671_V0.7780.09
155_G168_A0.7780.09
480_E484_W0.7780.09
586_E616_L0.7770.09
599_L633_V0.7750.09
176_S199_D0.7720.09
595_E630_H0.7720.09
501_K524_A0.7710.09
508_P676_E0.7700.09
549_R589_V0.7690.09
596_L730_F0.7690.09
311_R666_R0.7690.09
532_K540_Y0.7680.09
665_E708_S0.7680.09
475_K523_E0.7680.09
511_T643_E0.7670.09
540_Y549_R0.7650.09
519_A538_N0.7650.09
236_P480_E0.7640.09
593_L621_L0.7630.09
593_L628_D0.7630.09
549_R591_Q0.7630.09
165_I346_L0.7620.09
461_P499_P0.7600.09
317_L726_E0.7590.09
527_N615_D0.7590.09
511_T603_E0.7590.09
230_V258_I0.7540.09
500_A606_V0.7530.09
156_T170_Q0.7530.09
524_A683_A0.7520.09
633_V719_V0.7520.09
454_R617_I0.7510.09
161_N167_I0.7510.09
437_T668_D0.7490.09
294_E523_E0.7470.09
491_A551_V0.7450.09
523_E546_R0.7450.09
280_E283_E0.7440.09
528_F575_R0.7440.09
154_S163_T0.7440.09
540_Y591_Q0.7440.09
568_I727_T0.7440.09
468_V601_E0.7420.09
478_L633_V0.7390.09
455_E716_L0.7390.09
604_D622_L0.7370.09
535_E540_Y0.7360.09
568_I734_A0.7360.09
619_D648_H0.7330.09
164_E168_A0.7330.09
478_L497_L0.7330.09
491_A518_K0.7330.09
551_V585_G0.7330.09
151_T163_T0.7330.09
440_D520_V0.7310.09
575_R610_T0.7310.09
600_E633_V0.7290.09
193_E342_V0.7280.09
256_Q260_G0.7270.09
402_N663_L0.7260.09
399_D506_Y0.7220.09
249_N655_A0.7190.09
526_S581_D0.7190.09
598_G620_A0.7180.09
154_S159_V0.7180.09
160_Q169_D0.7170.09
257_T294_E0.7170.09
393_Q539_K0.7160.09
543_E546_R0.7150.09
673_A686_A0.7150.09
478_L608_I0.7140.09
655_A708_S0.7130.09
617_I688_R0.7120.09
534_P625_G0.7100.09
615_D677_A0.7100.09
244_A677_A0.7090.09
487_E617_I0.7080.09
338_R403_L0.7080.09
468_V478_L0.7060.09
240_K369_I0.7050.09
593_L673_A0.7050.09
343_D440_D0.7040.09
599_L669_G0.7030.09
180_G708_S0.7020.09
430_I706_E0.7010.09
333_I340_D0.7000.09
164_E169_D0.6990.09
572_A583_N0.6970.09
332_V659_D0.6970.09
469_G624_P0.6960.09
540_Y589_V0.6950.09
162_T169_D0.6940.09
269_G317_L0.6910.09
700_A708_S0.6910.09
491_A596_L0.6900.09
571_I609_A0.6900.09
167_I358_I0.6900.09
582_S600_E0.6880.09
295_L342_V0.6870.09
407_S664_V0.6850.09
499_P518_K0.6840.09
654_L672_G0.6830.09
517_A615_D0.6820.09
209_I215_H0.6810.09
540_Y544_S0.6800.09
234_G505_L0.6770.09
546_R617_I0.6730.09
237_G515_L0.6720.09
239_G534_P0.6700.08
310_E327_R0.6700.08
344_P609_A0.6700.08
589_V593_L0.6690.08
549_R588_V0.6660.08
333_I596_L0.6660.08
217_E222_L0.6650.08
519_A528_F0.6630.08
340_D585_G0.6630.08
481_T538_N0.6620.08
629_R727_T0.6620.08
263_I308_D0.6590.08
155_G165_I0.6590.08
578_G600_E0.6580.08
395_F518_K0.6580.08
532_K616_L0.6570.08
549_R616_L0.6550.08
372_I732_K0.6530.08
239_G544_S0.6530.08
586_E589_V0.6520.08
664_V675_I0.6490.08
540_Y625_G0.6490.08
536_L648_H0.6480.08
581_D586_E0.6480.08
258_I317_L0.6480.08
526_S727_T0.6470.08
591_Q622_L0.6470.08
516_L623_R0.6460.08
249_N646_E0.6440.08
584_V616_L0.6430.08
358_I721_S0.6430.08
505_L598_G0.6420.08
507_G510_G0.6410.08
507_G512_G0.6410.08
507_G513_K0.6410.08
507_G514_T0.6410.08
507_G545_E0.6410.08
507_G564_F0.6410.08
507_G614_P0.6410.08
507_G626_R0.6410.08
507_G674_D0.6410.08
510_G513_K0.6410.08
510_G514_T0.6410.08
510_G545_E0.6410.08
510_G564_F0.6410.08
510_G614_P0.6410.08
510_G626_R0.6410.08
510_G674_D0.6410.08
512_G545_E0.6410.08
512_G564_F0.6410.08
512_G614_P0.6410.08
512_G626_R0.6410.08
512_G674_D0.6410.08
513_K545_E0.6410.08
513_K564_F0.6410.08
513_K614_P0.6410.08
513_K626_R0.6410.08
513_K674_D0.6410.08
514_T545_E0.6410.08
514_T564_F0.6410.08
514_T614_P0.6410.08
514_T626_R0.6410.08
514_T674_D0.6410.08
545_E564_F0.6410.08
545_E614_P0.6410.08
545_E626_R0.6410.08
545_E674_D0.6410.08
564_F614_P0.6410.08
564_F626_R0.6410.08
564_F674_D0.6410.08
614_P626_R0.6410.08
614_P674_D0.6410.08
626_R674_D0.6410.08
463_V519_A0.6410.08
591_Q616_L0.6390.08
330_L333_I0.6370.08
170_Q654_L0.6350.08
410_H553_S0.6350.08
239_G532_K0.6350.08
540_Y572_A0.6350.08
289_I698_E0.6340.08
275_L371_Q0.6320.08
499_P511_T0.6320.08
405_K647_I0.6310.08
536_L576_G0.6310.08
584_V600_E0.6310.08
319_S655_A0.6300.08
298_I531_I0.6280.08
340_D668_D0.6280.08
346_L717_E0.6250.08
458_V518_K0.6240.08
535_E616_L0.6240.08
519_A630_H0.6240.08
404_V407_S0.6230.08
538_N624_P0.6230.08
257_T511_T0.6230.08
393_Q543_E0.6220.08
290_V735_E0.6220.08
568_I604_D0.6210.08
176_S181_E0.6210.08
489_A599_L0.6200.08
517_A613_R0.6180.08
156_T346_L0.6160.08
535_E591_Q0.6160.08
583_N616_L0.6140.08
534_P622_L0.6140.08
171_S357_E0.6130.08
478_L606_V0.6130.08
265_S316_Q0.6120.08
549_R625_G0.6120.08
578_G633_V0.6080.08
541_V591_Q0.6060.08
153_P158_V0.6040.08
181_E631_V0.6040.08
538_N615_D0.6030.08
366_R591_Q0.5990.08
577_Q600_E0.5990.08
497_L551_V0.5980.08
522_N617_I0.5970.08
239_G589_V0.5950.08
591_Q625_G0.5950.08
524_A538_N0.5940.08
565_F593_L0.5940.08
298_I370_L0.5940.08
289_I709_I0.5930.08
454_R571_I0.5920.08
524_A733_P0.5920.08
167_I170_Q0.5910.08
296_D648_H0.5900.08
298_I547_G0.5900.08
486_L585_G0.5890.08
484_W563_V0.5880.08
535_E625_G0.5880.08
544_S591_Q0.5880.08
589_V616_L0.5850.08
541_V544_S0.5850.08
468_V529_I0.5840.08
571_I723_A0.5780.08
289_I365_G0.5770.08
444_A515_L0.5760.08
543_E585_G0.5760.08
556_R617_I0.5750.08
635_E671_V0.5740.08
480_E620_A0.5740.08
152_Q161_N0.5730.08
712_F736_A0.5720.08
556_R608_I0.5720.08
508_P671_V0.5720.08
535_E541_V0.5720.08
544_S616_L0.5700.08
585_G636_P0.5690.08
483_Q499_P0.5640.08
646_E663_L0.5640.08
195_I327_R0.5640.08
401_E635_E0.5630.08
547_G669_G0.5630.08
549_R622_L0.5590.08
417_P706_E0.5590.08
456_V671_V0.5570.08
539_K620_A0.5570.08
685_V718_E0.5570.08
522_N712_F0.5560.08
534_P565_F0.5540.08
358_I581_D0.5540.08
540_Y622_L0.5530.08
252_D365_G0.5520.08
532_K549_R0.5510.08
568_I636_P0.5510.08
438_E631_V0.5490.08
535_E587_R0.5490.08
475_K527_N0.5480.08
486_L612_N0.5480.08
234_G344_P0.5480.08
356_I723_A0.5470.08
496_A602_L0.5470.08
192_Y348_R0.5460.08
239_G540_Y0.5450.08
589_V625_G0.5450.08
244_A404_V0.5440.08
535_E588_V0.5440.08
573_S589_V0.5440.08
478_L525_N0.5430.08
569_D575_R0.5420.08
239_G549_R0.5420.08
518_K676_E0.5420.08
320_L349_P0.5420.08
377_M645_F0.5410.08
395_F499_P0.5410.08
471_L485_P0.5410.08
485_P504_L0.5410.08
300_P311_R0.5400.08
571_I643_E0.5390.08
374_T441_F0.5360.07
456_V719_V0.5350.07
480_E687_V0.5340.07
388_Y656_E0.5340.07
546_R562_V0.5340.07
344_P358_I0.5330.07
511_T640_A0.5330.07
530_S730_F0.5320.07
173_Q332_V0.5300.07
346_L667_T0.5290.07
565_F588_V0.5250.07
592_L635_E0.5250.07
541_V633_V0.5240.07
225_E254_H0.5230.07
544_S625_G0.5230.07
403_L445_L0.5220.07
536_L643_E0.5220.07
586_E625_G0.5220.07
155_G164_E0.5220.07
609_A617_I0.5210.07
550_E677_A0.5200.07
616_L625_G0.5190.07
361_P678_V0.5190.07
542_G593_L0.5180.07
392_T530_S0.5170.07
474_A489_A0.5170.07
352_F523_E0.5170.07
528_F624_P0.5170.07
549_R584_V0.5150.07
535_E584_V0.5140.07
352_F536_L0.5140.07
156_T165_I0.5130.07
532_K591_Q0.5130.07
156_T159_V0.5110.07
185_T291_F0.5100.07
267_Y270_E0.5100.07
443_E723_A0.5100.07
567_E644_I0.5100.07
573_S584_V0.5100.07
263_I438_E0.5090.07
330_L340_D0.5090.07
511_T596_L0.5080.07
308_D547_G0.5070.07
174_E466_D0.5070.07
181_E200_D0.5060.07
554_K578_G0.5040.07
216_P219_F0.5040.07
496_A594_T0.5040.07
152_Q166_E0.5030.07
156_T160_Q0.5030.07
541_V621_L0.5030.07
541_V628_D0.5030.07
317_L655_A0.5010.07
501_K660_V0.5000.07
541_V584_V0.5000.07
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3cf2A 3 0.8874 100 0.603 Contact Map
3cmuA 1 0.787 100 0.721 Contact Map
4cr2J 1 0.4817 100 0.749 Contact Map
2x8aA 1 0.3148 100 0.757 Contact Map
4ko8A 3 0.5645 100 0.772 Contact Map
3cf0A 3 0.3772 100 0.782 Contact Map
1xwiA 1 0.3772 100 0.782 Contact Map
4cr2L 1 0.4695 100 0.782 Contact Map
2ce7A 3 0.3528 100 0.783 Contact Map
4cr2M 1 0.4545 100 0.783 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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