Q9HHV2 - HALSA - GREMLIN Contacts

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Q9HHV2 - Iron transport protein A

UniProt:	Q9HHV2	Sequences: MTGVGAVADTPAAHAESATLHAFLNCYLRETDAGEVVSPRAVPDGVPAGAQRADRRVVRVPFPAQSTTVFAPLRYASATGRHLFAVPAYARPGVPDAPAGTPSPIDAAGVASLARRELALDGDDPTAGRDLLERVLASQTATERFVAARDTPRDHERLYDTTVSFRDAEQSLVYGHHMHPTPNSRTGIPPHEQSRYAPELRAGFQLRVFAADPALVETWAAGDASATEWLRSVVADATTVPPESEATLVPVHPWQADYLHAQPHVAAAIARDELRDLGAFGPTFYPTSSVRTLWSPDAPFMYKGSLAVEITNAERTNKRPELARGVAVSELLATGFGDAFADRFPAFSIIEDPAAITLTLGDGAESGFEAVLRENPFAGDDTDNVTPVAALCQDGLDGPARAARIVSRIATREGRTESAVAREWFEQYLAHTVRPVVWLYFQQGVGLEAHQQNTLVRLDDDGRPTAGFYRDNQGYYFPASQAADVDDWLPGVCERADTVCPDAIADERLRYYIVFNNAFGVVNALGAGGVVDERALLAVLRTELESLAEHEPADSTLVSALLTERRVPCKANLLTRFEERDELEADLETQSVYTAIENPLVTRVDTQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	607 (544)
Sequences:	1856 (1276)
Seq/√Len:	54.7

HALSA - Q9HHV2 Q9HHU9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
211_A	274_L	7.291	1.00
207_R	276_D	4.495	1.00
422_R	535_A	4.409	1.00
566_R	595_A	4.363	1.00
430_A	543_E	4.043	1.00
426_E	539_V	3.940	1.00
241_P	275_R	3.903	1.00
164_S	167_D	3.799	1.00
106_D	109_G	3.727	1.00
110_V	114_A	3.722	1.00
426_E	542_T	3.675	1.00
216_V	247_T	3.397	1.00
457_R	466_A	3.378	1.00
383_D	466_A	3.303	1.00
457_R	468_F	3.193	1.00
212_D	273_E	3.192	1.00
225_S	228_E	3.160	1.00
204_F	293_L	3.159	1.00
383_D	459_D	3.082	1.00
385_V	455_L	3.002	1.00
427_Q	463_R	2.964	1.00
400_A	403_A	2.961	1.00
459_D	465_T	2.958	1.00
348_S	466_A	2.898	1.00
205_Q	279_A	2.806	1.00
246_A	275_R	2.787	1.00
212_D	246_A	2.756	1.00
543_E	546_S	2.615	1.00
439_L	447_L	2.610	1.00
213_P	247_T	2.579	1.00
284_F	295_S	2.556	1.00
215_L	273_E	2.535	1.00
436_V	509_L	2.523	1.00
426_E	543_E	2.436	1.00
351_E	374_E	2.426	1.00
209_F	256_A	2.414	1.00
254_W	307_A	2.414	1.00
293_L	304_G	2.309	1.00
412_R	462_G	2.305	1.00
205_Q	283_T	2.294	1.00
329_S	351_E	2.294	1.00
214_A	273_E	2.245	1.00
539_V	542_T	2.210	1.00
541_R	563_T	2.168	1.00
59_R	68_T	2.168	1.00
454_T	517_N	2.166	1.00
446_G	476_Y	2.151	1.00
518_A	540_L	2.145	1.00
438_W	547_L	2.092	1.00
210_A	246_A	2.088	1.00
511_Y	516_N	2.071	1.00
558_V	561_L	2.055	1.00
399_P	407_S	2.038	1.00
400_A	528_G	2.000	1.00
108_A	136_L	1.966	1.00
284_F	293_L	1.937	1.00
416_T	421_A	1.921	1.00
313_A	473_Q	1.907	1.00
366_S	369_E	1.879	0.99
382_T	459_D	1.874	0.99
429_L	539_V	1.862	0.99
508_R	576_R	1.844	0.99
312_N	511_Y	1.832	0.99
532_D	535_A	1.829	0.99
239_T	272_D	1.828	0.99
448_E	570_K	1.809	0.99
448_E	476_Y	1.783	0.99
311_T	576_R	1.780	0.99
211_A	249_V	1.780	0.99
67_T	91_R	1.773	0.99
18_A	22_A	1.745	0.99
269_I	276_D	1.721	0.99
203_G	285_Y	1.703	0.99
131_L	573_L	1.694	0.99
26_C	573_L	1.685	0.99
312_N	473_Q	1.684	0.99
421_A	525_L	1.679	0.99
312_N	512_Y	1.677	0.99
16_E	20_L	1.673	0.99
313_A	321_E	1.660	0.99
433_V	540_L	1.656	0.99
204_F	286_P	1.655	0.99
179_H	448_E	1.638	0.99
348_S	468_F	1.634	0.99
575_T	590_Q	1.626	0.98
62_F	114_A	1.619	0.98
221_A	330_E	1.617	0.98
196_Y	253_P	1.613	0.98
282_P	295_S	1.596	0.98
307_A	367_G	1.590	0.98
202_A	286_P	1.582	0.98
541_R	545_E	1.580	0.98
183_N	311_T	1.576	0.98
112_S	132_L	1.568	0.98
300_F	353_P	1.552	0.98
247_T	356_I	1.550	0.98
388_V	428_Y	1.545	0.98
178_M	520_G	1.528	0.98
565_R	601_V	1.522	0.98
103_S	109_G	1.522	0.98
317_N	508_R	1.517	0.98
479_A	501_P	1.516	0.98
388_V	451_Q	1.508	0.97
267_A	271_R	1.501	0.97
258_Y	262_Q	1.501	0.97
427_Q	430_A	1.496	0.97
301_M	376_P	1.491	0.97
312_N	321_E	1.484	0.97
226_A	230_L	1.478	0.97
313_A	366_S	1.461	0.97
134_R	576_R	1.460	0.97
511_Y	570_K	1.456	0.97
430_A	546_S	1.449	0.97
476_Y	500_C	1.434	0.97
380_D	383_D	1.414	0.96
325_G	473_Q	1.413	0.96
422_R	539_V	1.411	0.96
209_F	251_V	1.408	0.96
290_V	308_V	1.403	0.96
301_M	313_A	1.401	0.96
188_I	254_W	1.399	0.96
188_I	307_A	1.392	0.96
170_Q	201_R	1.391	0.96
347_F	469_Y	1.382	0.96
537_L	540_L	1.376	0.96
242_P	246_A	1.371	0.96
196_Y	246_A	1.369	0.96
448_E	508_R	1.369	0.96
566_R	597_E	1.367	0.96
320_P	324_R	1.366	0.95
213_P	245_E	1.363	0.95
222_G	225_S	1.359	0.95
321_E	474_G	1.357	0.95
227_T	231_R	1.356	0.95
166_R	285_Y	1.356	0.95
185_R	290_V	1.354	0.95
556_T	560_A	1.353	0.95
312_N	572_N	1.348	0.95
285_Y	296_P	1.332	0.95
188_I	306_L	1.329	0.95
92_P	99_A	1.327	0.95
175_G	311_T	1.323	0.95
498_T	502_D	1.322	0.95
212_D	245_E	1.322	0.95
191_H	195_R	1.313	0.94
182_P	511_Y	1.306	0.94
432_T	513_I	1.304	0.94
313_A	325_G	1.301	0.94
473_Q	476_Y	1.296	0.94
170_Q	285_Y	1.289	0.94
361_G	364_A	1.287	0.94
229_W	235_A	1.283	0.94
145_F	200_L	1.283	0.94
211_A	215_L	1.280	0.94
272_D	275_R	1.278	0.94
106_D	112_S	1.277	0.94
448_E	452_Q	1.276	0.93
508_R	575_T	1.276	0.93
180_P	448_E	1.261	0.93
304_G	308_V	1.260	0.93
72_P	85_A	1.247	0.93
176_H	311_T	1.246	0.93
448_E	474_G	1.244	0.93
333_A	351_E	1.240	0.92
268_A	273_E	1.236	0.92
473_Q	516_N	1.234	0.92
321_E	575_T	1.231	0.92
357_T	368_F	1.230	0.92
219_W	355_A	1.222	0.92
105_I	110_V	1.218	0.92
444_G	505_A	1.217	0.92
144_R	194_S	1.216	0.92
179_H	570_K	1.216	0.92
476_Y	498_T	1.213	0.92
421_A	531_V	1.210	0.92
311_T	472_N	1.207	0.91
189_P	192_E	1.205	0.91
268_A	358_L	1.203	0.91
434_R	543_E	1.201	0.91
311_T	512_Y	1.201	0.91
421_A	425_F	1.201	0.91
318_K	321_E	1.200	0.91
215_L	358_L	1.194	0.91
570_K	575_T	1.192	0.91
347_F	467_G	1.190	0.91
571_A	574_L	1.188	0.91
444_G	452_Q	1.186	0.91
228_E	232_S	1.185	0.91
545_E	549_E	1.184	0.91
246_A	272_D	1.181	0.91
514_V	518_A	1.174	0.90
109_G	113_L	1.173	0.90
440_Y	446_G	1.171	0.90
373_R	450_H	1.167	0.90
15_A	146_V	1.164	0.90
66_S	236_D	1.160	0.90
451_Q	472_N	1.160	0.90
476_Y	508_R	1.157	0.90
242_P	245_E	1.157	0.90
472_N	508_R	1.157	0.90
392_C	521_V	1.154	0.89
249_V	274_L	1.151	0.89
191_H	257_D	1.142	0.89
291_R	303_K	1.140	0.89
473_Q	508_R	1.138	0.89
301_M	473_Q	1.135	0.89
386_T	390_A	1.133	0.89
575_T	591_S	1.131	0.89
312_N	516_N	1.125	0.88
61_P	66_S	1.124	0.88
229_W	300_F	1.120	0.88
224_A	229_W	1.119	0.88
69_V	113_L	1.118	0.88
291_R	373_R	1.117	0.88
134_R	186_T	1.116	0.88
231_R	235_A	1.114	0.88
313_A	512_Y	1.113	0.88
74_R	85_A	1.110	0.88
255_Q	435_P	1.110	0.88
249_V	356_I	1.103	0.87
109_G	112_S	1.101	0.87
178_M	516_N	1.101	0.87
313_A	582_E	1.093	0.87
474_G	516_N	1.093	0.87
438_W	442_Q	1.092	0.87
538_A	542_T	1.092	0.87
548_A	559_S	1.091	0.87
217_E	359_T	1.089	0.87
412_R	461_D	1.082	0.86
210_A	277_L	1.079	0.86
472_N	575_T	1.078	0.86
16_E	360_L	1.076	0.86
473_Q	537_L	1.071	0.86
179_H	474_G	1.060	0.85
512_Y	575_T	1.058	0.85
167_D	201_R	1.057	0.85
343_R	346_A	1.055	0.85
557_L	560_A	1.052	0.85
185_R	515_F	1.052	0.85
25_N	29_R	1.048	0.84
317_N	473_Q	1.048	0.84
371_V	576_R	1.047	0.84
311_T	474_G	1.043	0.84
383_D	457_R	1.043	0.84
196_Y	204_F	1.042	0.84
291_R	450_H	1.040	0.84
243_E	246_A	1.040	0.84
509_L	514_V	1.039	0.84
213_P	518_A	1.036	0.84
178_M	576_R	1.030	0.83
321_E	512_Y	1.027	0.83
416_T	423_E	1.024	0.83
312_N	322_L	1.023	0.83
415_R	423_E	1.021	0.83
474_G	570_K	1.021	0.83
31_T	34_G	1.020	0.83
321_E	448_E	1.016	0.83
318_K	575_T	1.015	0.82
516_N	593_Y	1.012	0.82
206_L	281_G	1.011	0.82
424_W	435_P	1.011	0.82
211_A	216_V	1.006	0.82
403_A	528_G	1.006	0.82
24_L	244_S	1.002	0.82
137_A	141_A	1.000	0.81
508_R	570_K	0.998	0.81
428_Y	517_N	0.997	0.81
213_P	244_S	0.997	0.81
169_E	179_H	0.996	0.81
356_I	370_A	0.995	0.81
317_N	575_T	0.993	0.81
448_E	500_C	0.991	0.81
570_K	593_Y	0.988	0.81
352_D	576_R	0.982	0.80
531_V	539_V	0.981	0.80
307_A	314_E	0.980	0.80
115_R	121_D	0.979	0.80
182_P	573_L	0.978	0.80
491_G	494_E	0.978	0.80
203_G	283_T	0.977	0.80
448_E	573_L	0.977	0.80
182_P	312_N	0.976	0.80
69_V	110_V	0.976	0.80
321_E	473_Q	0.976	0.80
162_T	550_H	0.975	0.80
301_M	537_L	0.972	0.80
473_Q	581_D	0.968	0.79
20_L	107_A	0.967	0.79
473_Q	575_T	0.966	0.79
172_L	305_S	0.962	0.79
188_I	325_G	0.962	0.79
142_T	182_P	0.961	0.79
399_P	404_R	0.960	0.79
101_T	244_S	0.958	0.79
555_S	558_V	0.956	0.78
321_E	476_Y	0.953	0.78
302_Y	372_L	0.951	0.78
260_H	269_I	0.950	0.78
140_T	190_P	0.946	0.78
316_T	449_A	0.946	0.78
230_L	233_V	0.945	0.78
278_G	424_W	0.938	0.77
318_K	508_R	0.937	0.77
512_Y	582_E	0.936	0.77
392_C	517_N	0.931	0.77
325_G	451_Q	0.928	0.76
473_Q	512_Y	0.928	0.76
512_Y	576_R	0.928	0.76
19_T	182_P	0.926	0.76
315_R	471_D	0.924	0.76
556_T	561_L	0.924	0.76
195_R	204_F	0.923	0.76
77_S	84_F	0.922	0.76
547_L	551_E	0.921	0.76
414_G	539_V	0.920	0.76
341_A	551_E	0.919	0.76
373_R	471_D	0.919	0.76
405_I	458_L	0.916	0.75
311_T	424_W	0.915	0.75
81_R	520_G	0.914	0.75
19_T	146_V	0.911	0.75
283_T	297_D	0.910	0.75
69_V	91_R	0.910	0.75
425_F	525_L	0.909	0.75
228_E	231_R	0.907	0.75
413_E	463_R	0.907	0.75
489_L	493_C	0.907	0.75
198_P	464_P	0.903	0.74
291_R	315_R	0.903	0.74
108_A	267_A	0.901	0.74
255_Q	307_A	0.899	0.74
508_R	512_Y	0.896	0.74
432_T	454_T	0.895	0.74
180_P	452_Q	0.887	0.73
472_N	576_R	0.885	0.73
136_L	286_P	0.884	0.73
23_F	135_V	0.880	0.72
448_E	575_T	0.880	0.72
287_T	294_W	0.878	0.72
176_H	198_P	0.877	0.72
230_L	235_A	0.872	0.72
31_T	180_P	0.870	0.72
324_R	473_Q	0.870	0.72
294_W	301_M	0.868	0.71
290_V	306_L	0.868	0.71
237_A	240_V	0.867	0.71
546_S	549_E	0.867	0.71
312_N	575_T	0.866	0.71
313_A	581_D	0.866	0.71
305_S	322_L	0.866	0.71
278_G	515_F	0.854	0.70
426_E	430_A	0.853	0.70
476_Y	512_Y	0.852	0.70
326_V	354_A	0.852	0.70
74_R	527_A	0.851	0.70
512_Y	572_N	0.851	0.70
107_A	114_A	0.849	0.70
176_H	424_W	0.848	0.70
221_A	542_T	0.846	0.69
249_V	488_W	0.844	0.69
472_N	475_Y	0.843	0.69
18_A	406_V	0.842	0.69
210_A	243_E	0.841	0.69
241_P	272_D	0.840	0.69
596_I	599_P	0.840	0.69
472_N	512_Y	0.836	0.69
313_A	369_E	0.835	0.68
19_T	142_T	0.834	0.68
130_D	325_G	0.834	0.68
318_K	325_G	0.833	0.68
324_R	516_N	0.832	0.68
522_V	562_L	0.831	0.68
303_K	471_D	0.830	0.68
222_G	230_L	0.830	0.68
474_G	512_Y	0.829	0.68
508_R	511_Y	0.829	0.68
212_D	215_L	0.827	0.68
57_V	90_A	0.826	0.68
321_E	511_Y	0.825	0.68
475_Y	537_L	0.822	0.67
508_R	591_S	0.822	0.67
576_R	590_Q	0.821	0.67
319_R	369_E	0.820	0.67
545_E	563_T	0.816	0.67
396_L	399_P	0.816	0.67
403_A	529_G	0.816	0.67
535_A	539_V	0.815	0.67
423_E	427_Q	0.815	0.67
312_N	591_S	0.813	0.66
185_R	366_S	0.812	0.66
352_D	537_L	0.810	0.66
218_T	356_I	0.810	0.66
233_V	300_F	0.810	0.66
318_K	473_Q	0.809	0.66
522_V	540_L	0.808	0.66
276_D	279_A	0.806	0.66
449_A	512_Y	0.805	0.66
229_W	233_V	0.805	0.66
402_A	521_V	0.802	0.65
516_N	570_K	0.801	0.65
508_R	516_N	0.799	0.65
83_L	527_A	0.798	0.65
251_V	256_A	0.797	0.65
59_R	70_F	0.796	0.65
207_R	279_A	0.795	0.65
442_Q	553_A	0.793	0.64
571_A	594_T	0.790	0.64
131_L	470_R	0.790	0.64
208_V	250_P	0.785	0.64
474_G	593_Y	0.782	0.63
448_E	517_N	0.780	0.63
183_N	444_G	0.777	0.63
52_R	55_R	0.776	0.63
214_A	245_E	0.776	0.63
107_A	139_Q	0.776	0.63
257_D	276_D	0.773	0.62
374_E	600_L	0.772	0.62
448_E	576_R	0.772	0.62
62_F	66_S	0.771	0.62
313_A	477_F	0.769	0.62
180_P	570_K	0.767	0.62
178_M	570_K	0.766	0.62
452_Q	470_R	0.764	0.62
313_A	520_G	0.763	0.61
206_L	302_Y	0.763	0.61
397_D	404_R	0.762	0.61
434_R	544_L	0.760	0.61
406_V	534_R	0.759	0.61
20_L	110_V	0.759	0.61
517_N	521_V	0.758	0.61
165_F	473_Q	0.757	0.61
535_A	544_L	0.757	0.61
92_P	98_P	0.757	0.61
313_A	575_T	0.757	0.61
548_A	557_L	0.754	0.61
291_R	471_D	0.751	0.60
57_V	61_P	0.751	0.60
541_R	600_L	0.750	0.60
292_T	508_R	0.749	0.60
311_T	511_Y	0.748	0.60
176_H	447_L	0.745	0.60
358_L	368_F	0.745	0.60
77_S	82_H	0.744	0.59
210_A	275_R	0.743	0.59
61_P	68_T	0.743	0.59
390_A	521_V	0.742	0.59
293_L	308_V	0.742	0.59
314_E	516_N	0.737	0.59
229_W	232_S	0.737	0.59
334_T	546_S	0.737	0.59
101_T	126_T	0.736	0.59
66_S	546_S	0.735	0.59
500_C	508_R	0.733	0.58
148_A	308_V	0.730	0.58
150_D	279_A	0.730	0.58
176_H	576_R	0.730	0.58
341_A	345_P	0.729	0.58
56_R	211_A	0.729	0.58
337_G	456_V	0.729	0.58
178_M	184_S	0.727	0.58
224_A	228_E	0.725	0.57
369_E	475_Y	0.724	0.57
26_C	519_F	0.723	0.57
225_S	271_R	0.723	0.57
18_A	62_F	0.721	0.57
315_R	373_R	0.721	0.57
201_R	564_E	0.718	0.57
113_L	118_L	0.718	0.57
131_L	576_R	0.718	0.57
110_V	113_L	0.717	0.57
165_F	301_M	0.717	0.57
447_L	469_Y	0.716	0.57
231_R	236_D	0.716	0.57
526_G	533_E	0.714	0.56
195_R	205_Q	0.714	0.56
292_T	573_L	0.714	0.56
506_D	511_Y	0.713	0.56
328_V	442_Q	0.712	0.56
318_K	507_E	0.712	0.56
452_Q	471_D	0.711	0.56
352_D	475_Y	0.710	0.56
373_R	452_Q	0.710	0.56
192_E	270_A	0.709	0.56
212_D	358_L	0.705	0.55
313_A	476_Y	0.705	0.55
178_M	447_L	0.704	0.55
175_G	375_N	0.704	0.55
452_Q	476_Y	0.703	0.55
303_K	315_R	0.702	0.55
325_G	472_N	0.702	0.55
248_L	391_L	0.701	0.55
399_P	414_G	0.696	0.54
497_D	500_C	0.696	0.54
225_S	229_W	0.696	0.54
369_E	478_P	0.695	0.54
324_R	476_Y	0.694	0.54
448_E	472_N	0.692	0.54
389_A	392_C	0.692	0.54
514_V	548_A	0.690	0.54
109_G	390_A	0.689	0.54
114_A	118_L	0.689	0.54
388_V	432_T	0.688	0.54
451_Q	537_L	0.688	0.54
16_E	573_L	0.688	0.54
514_V	540_L	0.687	0.53
177_H	451_Q	0.687	0.53
312_N	474_G	0.686	0.53
512_Y	590_Q	0.686	0.53
446_G	575_T	0.685	0.53
476_Y	575_T	0.684	0.53
160_D	283_T	0.684	0.53
99_A	542_T	0.684	0.53
199_E	253_P	0.682	0.53
301_M	325_G	0.682	0.53
166_R	377_F	0.682	0.53
312_N	576_R	0.681	0.53
180_P	313_A	0.680	0.53
169_E	470_R	0.680	0.53
179_H	452_Q	0.679	0.53
91_R	113_L	0.674	0.52
92_P	101_T	0.672	0.52
232_S	235_A	0.672	0.52
452_Q	474_G	0.671	0.52
313_A	446_G	0.669	0.52
376_P	385_V	0.668	0.51
376_P	379_G	0.668	0.51
311_T	329_S	0.668	0.51
216_V	356_I	0.665	0.51
87_P	90_A	0.664	0.51
439_L	445_V	0.664	0.51
474_G	576_R	0.664	0.51
98_P	102_P	0.662	0.51
334_T	337_G	0.662	0.51
12_A	147_A	0.661	0.51
476_Y	497_D	0.661	0.51
314_E	571_A	0.661	0.51
184_S	367_G	0.660	0.51
158_L	461_D	0.660	0.51
19_T	22_A	0.660	0.51
415_R	463_R	0.660	0.51
437_V	537_L	0.659	0.50
55_R	100_G	0.659	0.50
270_A	414_G	0.659	0.50
178_M	448_E	0.658	0.50
331_L	490_P	0.654	0.50
515_F	569_C	0.654	0.50
228_E	234_V	0.653	0.50
287_T	301_M	0.652	0.50
253_P	599_P	0.652	0.50
422_R	531_V	0.650	0.50
248_L	432_T	0.649	0.49
191_H	422_R	0.648	0.49
225_S	232_S	0.648	0.49
53_A	56_R	0.648	0.49
134_R	572_N	0.648	0.49
255_Q	599_P	0.648	0.49
204_F	290_V	0.647	0.49
260_H	276_D	0.647	0.49
480_S	502_D	0.645	0.49
138_S	310_I	0.644	0.49
348_S	379_G	0.644	0.49
181_T	318_K	0.643	0.49
228_E	239_T	0.642	0.49
322_L	572_N	0.642	0.49
473_Q	497_D	0.641	0.49
119_A	128_G	0.640	0.48
311_T	452_Q	0.639	0.48
423_E	426_E	0.639	0.48
440_Y	505_A	0.639	0.48
303_K	373_R	0.638	0.48
106_D	601_V	0.638	0.48
507_E	570_K	0.637	0.48
310_I	424_W	0.637	0.48
511_Y	572_N	0.636	0.48
101_T	269_I	0.633	0.48
208_V	317_N	0.633	0.48
297_D	535_A	0.630	0.47
431_H	464_P	0.630	0.47
469_Y	472_N	0.629	0.47
553_A	556_T	0.628	0.47
228_E	549_E	0.627	0.47
510_R	567_V	0.626	0.47
341_A	346_A	0.625	0.47
406_V	421_A	0.625	0.47
16_E	34_G	0.624	0.47
576_R	599_P	0.624	0.47
322_L	355_A	0.624	0.47
257_D	279_A	0.622	0.47
112_S	545_E	0.622	0.47
209_F	269_I	0.622	0.47
77_S	523_N	0.622	0.47
321_E	582_E	0.621	0.46
214_A	480_S	0.621	0.46
311_T	375_N	0.620	0.46
28_L	249_V	0.620	0.46
27_Y	131_L	0.619	0.46
195_R	403_A	0.619	0.46
204_F	370_A	0.619	0.46
180_P	200_L	0.618	0.46
15_A	19_T	0.618	0.46
451_Q	516_N	0.618	0.46
198_P	389_A	0.617	0.46
74_R	550_H	0.617	0.46
328_V	475_Y	0.616	0.46
315_R	450_H	0.616	0.46
54_D	57_V	0.615	0.46
461_D	503_A	0.615	0.46
472_N	581_D	0.614	0.46
157_R	160_D	0.614	0.46
429_L	540_L	0.613	0.46
178_M	328_V	0.613	0.46
318_K	576_R	0.612	0.45
166_R	447_L	0.611	0.45
176_H	512_Y	0.610	0.45
321_E	355_A	0.607	0.45
106_D	110_V	0.607	0.45
321_E	508_R	0.607	0.45
62_F	293_L	0.606	0.45
303_K	450_H	0.605	0.45
512_Y	516_N	0.604	0.45
14_H	242_P	0.604	0.45
450_H	453_N	0.604	0.45
448_E	498_T	0.604	0.45
305_S	321_E	0.604	0.45
288_S	310_I	0.602	0.44
311_T	515_F	0.601	0.44
60_V	192_E	0.600	0.44
24_L	107_A	0.600	0.44
312_N	476_Y	0.600	0.44
29_R	570_K	0.599	0.44
230_L	249_V	0.598	0.44
307_A	441_F	0.597	0.44
325_G	352_D	0.597	0.44
299_P	543_E	0.596	0.44
215_L	361_G	0.596	0.44
179_H	313_A	0.595	0.44
26_C	180_P	0.595	0.44
317_N	476_Y	0.594	0.44
56_R	161_T	0.594	0.44
318_K	472_N	0.594	0.44
198_P	292_T	0.594	0.44
554_D	558_V	0.592	0.43
163_V	384_N	0.591	0.43
232_S	338_D	0.591	0.43
266_A	270_A	0.590	0.43
321_E	500_C	0.587	0.43
63_P	117_E	0.587	0.43
423_E	463_R	0.587	0.43
389_A	467_G	0.585	0.43
52_R	535_A	0.585	0.43
30_E	289_S	0.584	0.42
72_P	531_V	0.584	0.42
142_T	146_V	0.583	0.42
432_T	489_L	0.583	0.42
176_H	428_Y	0.583	0.42
369_E	472_N	0.582	0.42
437_V	497_D	0.580	0.42
26_C	569_C	0.579	0.42
250_P	370_A	0.578	0.42
179_H	470_R	0.576	0.42
336_F	349_I	0.575	0.42
448_E	512_Y	0.574	0.41
60_V	565_R	0.574	0.41
312_N	582_E	0.572	0.41
509_L	582_E	0.571	0.41
446_G	473_Q	0.571	0.41
372_L	424_W	0.569	0.41
166_R	288_S	0.569	0.41
321_E	591_S	0.569	0.41
178_M	188_I	0.569	0.41
225_S	274_L	0.568	0.41
446_G	508_R	0.567	0.41
311_T	508_R	0.566	0.41
318_K	474_G	0.566	0.41
28_L	349_I	0.566	0.41
296_P	595_A	0.566	0.41
67_T	113_L	0.566	0.41
449_A	509_L	0.565	0.41
101_T	333_A	0.565	0.41
325_G	355_A	0.565	0.41
138_S	470_R	0.564	0.40
195_R	279_A	0.563	0.40
306_L	524_A	0.562	0.40
511_Y	575_T	0.562	0.40
38_S	99_A	0.561	0.40
70_F	90_A	0.561	0.40
388_V	473_Q	0.561	0.40
357_T	369_E	0.561	0.40
220_A	223_D	0.560	0.40
13_A	143_E	0.560	0.40
373_R	453_N	0.559	0.40
476_Y	570_K	0.559	0.40
287_T	305_S	0.558	0.40
476_Y	505_A	0.558	0.40
19_T	23_F	0.558	0.40
535_A	538_A	0.557	0.40
131_L	347_F	0.556	0.40
22_A	444_G	0.556	0.40
141_A	145_F	0.556	0.40
208_V	248_L	0.556	0.40
208_V	577_F	0.556	0.40
433_V	514_V	0.556	0.40
318_K	590_Q	0.556	0.40
439_L	449_A	0.555	0.39
255_Q	576_R	0.554	0.39
182_P	310_I	0.554	0.39
337_G	426_E	0.554	0.39
145_F	286_P	0.554	0.39
225_S	541_R	0.553	0.39
218_T	247_T	0.552	0.39
301_M	451_Q	0.552	0.39
144_R	200_L	0.551	0.39
325_G	449_A	0.551	0.39
497_D	502_D	0.551	0.39
278_G	435_P	0.550	0.39
138_S	175_G	0.550	0.39
328_V	576_R	0.550	0.39
475_Y	580_R	0.549	0.39
496_A	500_C	0.548	0.39
310_I	572_N	0.548	0.39
278_G	328_V	0.546	0.39
176_H	449_A	0.546	0.39
337_G	344_F	0.544	0.38
341_A	344_F	0.544	0.38
386_T	458_L	0.543	0.38
349_I	541_R	0.543	0.38
312_N	497_D	0.543	0.38
120_L	290_V	0.542	0.38
232_S	501_P	0.542	0.38
184_S	310_I	0.542	0.38
366_S	575_T	0.542	0.38
333_A	378_A	0.541	0.38
520_G	537_L	0.541	0.38
474_G	511_Y	0.541	0.38
231_R	343_R	0.540	0.38
136_L	143_E	0.540	0.38
25_N	287_T	0.539	0.38
27_Y	317_N	0.539	0.38
60_V	119_A	0.537	0.38
143_E	216_V	0.537	0.38
575_T	583_L	0.536	0.38
339_A	343_R	0.536	0.38
52_R	56_R	0.535	0.37
545_E	559_S	0.535	0.37
166_R	287_T	0.534	0.37
147_A	461_D	0.534	0.37
178_M	474_G	0.533	0.37
64_A	491_G	0.533	0.37
310_I	317_N	0.533	0.37
396_L	416_T	0.532	0.37
237_A	297_D	0.532	0.37
325_G	476_Y	0.532	0.37
550_H	559_S	0.531	0.37
454_T	467_G	0.531	0.37
550_H	565_R	0.530	0.37
368_F	447_L	0.529	0.37
447_L	574_L	0.528	0.37
187_G	199_E	0.528	0.37
169_E	255_Q	0.528	0.37
474_G	498_T	0.526	0.37
134_R	317_N	0.526	0.37
146_V	229_W	0.526	0.37
208_V	352_D	0.526	0.37
194_S	267_A	0.526	0.37
352_D	581_D	0.525	0.36
384_N	462_G	0.525	0.36
347_F	454_T	0.525	0.36
387_P	505_A	0.524	0.36
322_L	447_L	0.524	0.36
473_Q	576_R	0.523	0.36
101_T	416_T	0.522	0.36
531_V	538_A	0.522	0.36
421_A	426_E	0.521	0.36
151_T	232_S	0.521	0.36
344_F	550_H	0.521	0.36
312_N	449_A	0.520	0.36
544_L	548_A	0.519	0.36
482_A	507_E	0.519	0.36
309_E	580_R	0.518	0.36
165_F	376_P	0.517	0.36
208_V	284_F	0.517	0.36
55_R	60_V	0.516	0.36
141_A	193_Q	0.516	0.36
54_D	546_S	0.516	0.36
245_E	479_A	0.516	0.36
157_R	337_G	0.515	0.35
447_L	474_G	0.515	0.35
435_P	464_P	0.514	0.35
25_N	84_F	0.514	0.35
220_A	226_A	0.514	0.35
215_L	274_L	0.513	0.35
425_F	429_L	0.513	0.35
134_R	475_Y	0.513	0.35
450_H	599_P	0.512	0.35
476_Y	583_L	0.512	0.35
523_N	527_A	0.512	0.35
294_W	317_N	0.511	0.35
226_A	247_T	0.511	0.35
452_Q	570_K	0.511	0.35
176_H	474_G	0.511	0.35
391_L	598_N	0.511	0.35
172_L	512_Y	0.511	0.35
548_A	563_T	0.510	0.35
24_L	110_V	0.510	0.35
176_H	373_R	0.509	0.35
313_A	513_I	0.508	0.35
185_R	424_W	0.508	0.35
198_P	286_P	0.506	0.35
54_D	59_R	0.506	0.35
350_I	464_P	0.505	0.34
144_R	190_P	0.504	0.34
474_G	508_R	0.504	0.34
374_E	378_A	0.503	0.34
66_S	92_P	0.502	0.34
56_R	68_T	0.501	0.34
53_A	330_E	0.500	0.34

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2x3jA	2	0.9341	100	0.191	Contact Map
3to3A	2	0.9127	100	0.225	Contact Map
2x0qA	2	0.911	100	0.237	Contact Map
1rr7A	2	0.1549	30.8	0.978	Contact Map
3f2kA	1	0.3229	10.6	0.982	Contact Map
2g31A	1	0.0988	5.1	0.985	Contact Map
4parB	3	0.1565	3.8	0.986	Contact Map
4db5A	6	0.196	3.5	0.986	Contact Map
2dt6A	1	0.1021	3.4	0.986	Contact Map
4fakA	2	0.2389	3.3	0.986	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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