Q9HHV1 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q9HHV1 - Iron transport protein B

UniProt:	Q9HHV1	Sequences: MTAPLPRITSDYAYRRPDPQIDRTVAFRRVALDRDLGRLHAWLTSDHVTPYWSLGAPLPAFHQAIGDHLEDDHVTAYVGCIDGVPMSYVERYWVAADPLADHYDADDNDQGIHILIGPPEYLGQGCGTALLRAMTALAFRHAATDRVVAEPDATNDAAIAAFERAGFEPRETFRFPHEDKDATRVVCDRERFVGAFSPGAIAANGPPADGPAVNHDDATHRCPSGEHGNSTLEADR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	236 (184)
Sequences:	717 (485)
Seq/√Len:	35.7

HALSA - Q9HHV1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
28_R	35_D	5.811	1.00
174_R	181_D	4.288	1.00
37_G	58_L	4.092	1.00
28_R	80_C	3.517	1.00
79_G	87_S	2.877	1.00
84_V	120_E	2.784	1.00
44_T	56_A	2.694	1.00
95_A	107_D	2.552	1.00
135_T	167_F	2.428	1.00
41_A	118_P	2.411	1.00
77_Y	91_R	2.399	1.00
169_P	183_T	2.325	0.99
106_D	145_D	2.250	0.99
62_H	66_G	2.236	0.99
13_A	77_Y	2.232	0.99
66_G	70_E	2.157	0.99
28_R	78_V	2.062	0.99
149_A	185_V	1.991	0.98
114_I	131_L	1.985	0.98
172_T	181_D	1.940	0.98
102_H	176_P	1.924	0.98
30_V	39_L	1.902	0.98
103_Y	184_R	1.885	0.98
91_R	138_A	1.879	0.98
103_Y	186_V	1.819	0.97
114_I	158_A	1.738	0.96
57_P	60_A	1.725	0.96
172_T	183_T	1.711	0.96
69_L	76_A	1.706	0.96
170_R	186_V	1.686	0.95
97_D	100_A	1.667	0.95
31_A	34_R	1.659	0.95
30_V	65_I	1.649	0.95
10_S	28_R	1.648	0.95
146_R	186_V	1.624	0.94
45_S	119_P	1.580	0.93
110_Q	144_T	1.577	0.93
56_A	60_A	1.569	0.93
113_H	150_E	1.514	0.92
168_E	191_R	1.500	0.91
159_I	162_F	1.499	0.91
150_E	180_K	1.431	0.89
48_V	65_I	1.387	0.88
33_D	62_H	1.380	0.87
30_V	76_A	1.372	0.87
48_V	117_G	1.370	0.87
134_M	147_V	1.350	0.86
158_A	162_F	1.345	0.86
149_A	155_N	1.324	0.85
65_I	88_Y	1.314	0.85
64_A	68_H	1.312	0.85
21_I	25_V	1.302	0.84
77_Y	137_L	1.301	0.84
41_A	45_S	1.294	0.84
112_I	155_N	1.284	0.83
36_L	58_L	1.280	0.83
54_L	61_F	1.268	0.83
76_A	88_Y	1.263	0.82
149_A	158_A	1.261	0.82
94_V	99_L	1.250	0.82
191_R	195_A	1.235	0.81
58_L	62_H	1.224	0.80
169_P	185_V	1.218	0.80
170_R	183_T	1.217	0.80
43_L	65_I	1.208	0.79
12_Y	15_R	1.202	0.79
163_E	169_P	1.201	0.79
131_L	158_A	1.194	0.78
18_D	132_R	1.181	0.78
16_R	136_A	1.168	0.77
26_A	80_C	1.168	0.77
15_R	26_A	1.164	0.77
112_I	158_A	1.161	0.76
116_I	127_G	1.146	0.76
157_A	161_A	1.136	0.75
117_G	123_G	1.133	0.75
15_R	24_T	1.116	0.74
71_D	74_V	1.115	0.74
181_D	193_V	1.106	0.73
169_P	172_T	1.103	0.73
103_Y	148_V	1.102	0.73
128_T	164_R	1.100	0.72
25_V	87_S	1.090	0.72
155_N	158_A	1.087	0.72
131_L	162_F	1.079	0.71
48_V	123_G	1.078	0.71
56_A	61_F	1.069	0.70
78_V	96_A	1.051	0.69
89_V	162_F	1.042	0.68
75_T	91_R	1.037	0.68
112_I	149_A	1.031	0.67
92_Y	113_H	1.027	0.67
94_V	148_V	1.004	0.65
127_G	161_A	0.982	0.64
156_D	163_E	0.981	0.64
93_W	144_T	0.977	0.63
89_V	134_M	0.977	0.63
81_I	86_M	0.965	0.62
81_I	123_G	0.958	0.62
100_A	173_F	0.956	0.62
55_G	58_L	0.953	0.61
139_F	187_C	0.951	0.61
25_V	130_L	0.947	0.61
113_H	180_K	0.939	0.60
27_F	134_M	0.928	0.59
38_R	41_A	0.928	0.59
99_L	164_R	0.925	0.59
110_Q	117_G	0.924	0.59
124_Q	132_R	0.920	0.59
148_V	186_V	0.905	0.57
68_H	76_A	0.904	0.57
112_I	162_F	0.902	0.57
29_R	69_L	0.891	0.56
94_V	108_N	0.888	0.56
151_P	155_N	0.888	0.56
43_L	64_A	0.871	0.54
63_Q	67_D	0.871	0.54
78_V	85_P	0.869	0.54
18_D	21_I	0.867	0.54
153_A	172_T	0.866	0.54
15_R	131_L	0.862	0.54
54_L	68_H	0.857	0.53
64_A	67_D	0.848	0.52
47_H	157_A	0.841	0.52
149_A	162_F	0.840	0.52
100_A	174_R	0.823	0.50
53_S	98_P	0.819	0.50
87_S	121_Y	0.812	0.49
136_A	143_A	0.807	0.49
102_H	175_F	0.807	0.49
99_L	148_V	0.804	0.49
63_Q	66_G	0.796	0.48
136_A	192_F	0.795	0.48
90_E	187_C	0.795	0.48
79_G	90_E	0.793	0.48
33_D	66_G	0.793	0.48
117_G	150_E	0.793	0.48
112_I	138_A	0.789	0.47
108_N	143_A	0.779	0.46
14_Y	140_R	0.778	0.46
68_H	74_V	0.769	0.46
43_L	48_V	0.761	0.45
13_A	29_R	0.760	0.45
91_R	154_T	0.756	0.44
31_A	173_F	0.755	0.44
45_S	128_T	0.755	0.44
48_V	115_L	0.751	0.44
95_A	105_A	0.745	0.43
150_E	182_A	0.743	0.43
66_G	84_V	0.736	0.43
14_Y	143_A	0.727	0.42
92_Y	111_G	0.726	0.42
121_Y	139_F	0.725	0.42
73_H	90_E	0.723	0.42
11_D	131_L	0.721	0.41
98_P	177_H	0.717	0.41
55_G	116_I	0.714	0.41
116_I	124_Q	0.707	0.40
93_W	96_A	0.704	0.40
110_Q	130_L	0.703	0.40
17_P	22_D	0.701	0.40
153_A	175_F	0.698	0.40
117_G	144_T	0.696	0.39
122_L	126_C	0.694	0.39
33_D	63_Q	0.689	0.39
138_A	147_V	0.688	0.39
30_V	69_L	0.686	0.39
51_Y	155_N	0.684	0.38
18_D	133_A	0.683	0.38
127_G	165_A	0.683	0.38
10_S	29_R	0.677	0.38
42_W	113_H	0.677	0.38
81_I	136_A	0.675	0.38
80_C	85_P	0.672	0.37
159_I	169_P	0.667	0.37
36_L	54_L	0.667	0.37
73_H	96_A	0.666	0.37
54_L	60_A	0.662	0.37
72_D	116_I	0.662	0.37
55_G	60_A	0.659	0.36
98_P	101_D	0.657	0.36
50_P	78_V	0.647	0.35
159_I	183_T	0.643	0.35
97_D	157_A	0.631	0.34
46_D	50_P	0.631	0.34
172_T	193_V	0.631	0.34
92_Y	166_G	0.630	0.34
109_D	113_H	0.628	0.34
127_G	134_M	0.627	0.34
135_T	166_G	0.627	0.34
98_P	176_P	0.626	0.34
87_S	165_A	0.625	0.34
25_V	174_R	0.623	0.34
149_A	157_A	0.618	0.33
141_H	189_R	0.615	0.33
21_I	83_G	0.612	0.33
131_L	165_A	0.611	0.33
27_F	123_G	0.610	0.33
27_F	70_E	0.609	0.32
92_Y	150_E	0.608	0.32
27_F	121_Y	0.608	0.32
13_A	18_D	0.605	0.32
43_L	115_L	0.600	0.32
19_P	174_R	0.600	0.32
97_D	175_F	0.599	0.32
122_L	139_F	0.599	0.32
114_I	185_V	0.596	0.31
162_F	167_F	0.591	0.31
40_H	152_D	0.589	0.31
42_W	150_E	0.585	0.31
46_D	55_G	0.582	0.30
26_A	85_P	0.580	0.30
130_L	162_F	0.580	0.30
106_D	153_A	0.577	0.30
12_Y	80_C	0.576	0.30
16_R	140_R	0.573	0.30
59_P	141_H	0.571	0.30
97_D	177_H	0.570	0.30
168_E	188_D	0.568	0.29
102_H	173_F	0.566	0.29
109_D	146_R	0.565	0.29
73_H	79_G	0.563	0.29
32_L	194_G	0.563	0.29
43_L	74_V	0.557	0.29
105_A	108_N	0.556	0.29
15_R	70_E	0.555	0.28
173_F	184_R	0.550	0.28
37_G	117_G	0.549	0.28
95_A	163_E	0.547	0.28
86_M	130_L	0.547	0.28
123_G	147_V	0.544	0.28
124_Q	175_F	0.544	0.28
70_E	147_V	0.544	0.28
46_D	116_I	0.542	0.28
97_D	102_H	0.541	0.28
118_P	123_G	0.540	0.27
85_P	172_T	0.539	0.27
51_Y	180_K	0.538	0.27
31_A	120_E	0.538	0.27
127_G	162_F	0.538	0.27
149_A	182_A	0.537	0.27
47_H	50_P	0.537	0.27
25_V	81_I	0.537	0.27
139_F	142_A	0.536	0.27
146_R	184_R	0.536	0.27
36_L	61_F	0.529	0.27
48_V	88_Y	0.529	0.27
44_T	61_F	0.529	0.27
36_L	62_H	0.529	0.27
190_E	195_A	0.526	0.26
25_V	161_A	0.525	0.26
155_N	166_G	0.524	0.26
27_F	133_A	0.521	0.26
99_L	102_H	0.521	0.26
92_Y	155_N	0.520	0.26
90_E	158_A	0.517	0.26
128_T	132_R	0.516	0.26
24_T	82_D	0.515	0.26
43_L	88_Y	0.515	0.26
78_V	171_E	0.514	0.26
133_A	193_V	0.511	0.25
18_D	25_V	0.511	0.25
9_T	83_G	0.511	0.25
150_E	162_F	0.510	0.25
79_G	135_T	0.508	0.25
99_L	175_F	0.506	0.25
148_V	184_R	0.506	0.25
51_Y	156_D	0.505	0.25
13_A	37_G	0.505	0.25
39_L	43_L	0.505	0.25
25_V	133_A	0.504	0.25
100_A	181_D	0.503	0.25
48_V	87_S	0.503	0.25
162_F	165_A	0.502	0.25
159_I	171_E	0.502	0.25
37_G	40_H	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2qmlA	2	0.8178	100	0.648	Contact Map
1yk3A	2	0.7797	99.9	0.719	Contact Map
2bueA	1	0.7373	99.7	0.769	Contact Map
3f5bA	1	0.7161	99.6	0.788	Contact Map
4r9mA	5	0.6864	99.4	0.811	Contact Map
2z10A	2	0.7627	99.4	0.812	Contact Map
4mi4A	5	0.6992	99.4	0.815	Contact Map
4ri1A	2	0.7373	99.3	0.822	Contact Map
4qc6A	1	0.7203	99.3	0.823	Contact Map
3tthA	5	0.6653	99.3	0.826	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0075 seconds.