Q9HHU7 - HALSA - GREMLIN Contacts

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Q9HHU7 - Cationic amino acid transporter

UniProt:	Q9HHU7	Sequences: MSSSQTRSPDAELGLLDATMIGMGAMIGAGIFVLTGLAAEIAGPAAILVFALNGVVTAFTGLSYAELAASIPKSGGGYAFVREIFGDFSSFIMGWMLWFAYMIAGALYALGFAPNFLELLHVYGLVAPPDQVGAIAVPLLDASVPAAFVLAFIAVLGLVALNAVSTAASGSAETIFTIIKVSILVVFVAFGATSPLFSGAEFQPLFGVGGGPAAILPAMGLTFIAFEGYDLITTVTEEVKNPRENIPKAIFVSLIATVIVYLAVVTVAVGTLGADGLAAAGEAGIAEAATSFMPTGLPIIQNGGALIVFGAVFSTLTALNAVVIASSRVAFSMGREGQLLPSFGQIHHRYGTPFVAIIASAVVMLASVALPTQSAGNMSSLFFLLSFIIVNVAVIRLRRERPDMNRPYEMPFYPAPPLIGIALNLVLSVVLVDYLVRTDPLALALSAAWIVLGTAAYYAHASRQSAAGDDEDTTTISADAEHTPHDH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	487 (422)
Sequences:	24883 (16312)
Seq/√Len:	794.1

ECOLI - PUUP PLAP PROY ANSP LYSP GADC FRLA AROP YIFK MMUP POTE ADIC GABP YGJI ARCD YBAT PHEP CYCA YCAM YJEM CADB YJEH
BACSU - ASPP YBEC GABP YTNA ROCC YHDG YBXG YFNA STET YBGF HUTM YDGF AAPA YVBW ROCE ARCD YCGH YECA YDAO GERBB GERAB YNDE GERKB
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97X49 Q97WS3 Q97XM0 Q97Z63 Q97VA8 Q97U05 Q97U33 Q7LXI7 Q97VA6 Q97VR4 Q97ZB5 Q97WD4 Q97Y76 Q97YX9 Q97YN3 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
342_S	355_V	4.295	1.00
159_V	361_A	4.283	1.00
54_G	258_V	3.203	1.00
345_Q	355_V	3.113	1.00
244_E	248_K	2.960	1.00
14_G	240_K	2.930	1.00
347_H	350_Y	2.849	1.00
239_V	245_N	2.665	1.00
241_N	244_E	2.641	1.00
94_G	333_M	2.608	1.00
78_Y	336_E	2.541	1.00
191_G	267_V	2.536	1.00
334_G	344_G	2.498	1.00
342_S	345_Q	2.455	1.00
347_H	354_F	2.450	1.00
396_R	400_E	2.450	1.00
19_T	252_V	2.430	1.00
388_I	421_I	2.425	1.00
189_A	193_T	2.383	1.00
15_L	252_V	2.344	1.00
152_F	365_L	2.279	1.00
237_E	335_R	2.266	1.00
66_E	398_R	2.215	1.00
331_F	335_R	2.112	1.00
82_R	90_S	2.108	1.00
160_A	164_V	2.101	1.00
358_I	362_V	2.095	1.00
238_E	328_R	2.092	1.00
15_L	245_N	2.089	1.00
159_V	357_I	2.032	1.00
167_A	171_S	2.027	1.00
15_L	19_T	2.008	1.00
418_L	422_A	2.006	1.00
18_A	239_V	2.003	1.00
449_W	453_G	2.002	1.00
163_A	354_F	1.998	1.00
391_N	420_G	1.995	1.00
152_F	368_V	1.993	1.00
248_K	252_V	1.988	1.00
85_F	396_R	1.954	1.00
82_R	87_D	1.952	1.00
290_T	293_M	1.941	1.00
63_S	391_N	1.909	1.00
178_I	182_S	1.908	1.00
55_V	59_F	1.899	1.00
337_G	341_P	1.884	1.00
98_W	360_S	1.865	1.00
14_G	17_D	1.856	1.00
343_F	359_A	1.829	1.00
447_A	451_V	1.829	1.00
9_P	346_I	1.820	1.00
299_I	306_L	1.811	1.00
422_A	426_V	1.807	1.00
455_A	459_A	1.799	1.00
85_F	392_V	1.783	1.00
273_G	276_G	1.767	1.00
151_A	368_V	1.759	1.00
38_A	46_A	1.739	1.00
17_D	174_T	1.736	1.00
439_D	442_A	1.728	1.00
251_F	255_I	1.727	1.00
81_V	93_M	1.718	1.00
420_G	431_L	1.713	1.00
241_N	245_N	1.700	1.00
207_G	210_G	1.677	1.00
156_L	365_L	1.675	1.00
156_L	361_A	1.671	1.00
276_G	294_P	1.670	1.00
202_F	205_L	1.655	1.00
93_M	389_I	1.655	1.00
109_A	319_L	1.650	1.00
413_Y	417_P	1.640	1.00
182_S	186_V	1.637	1.00
198_S	201_E	1.629	1.00
350_Y	354_F	1.603	1.00
426_V	430_V	1.601	1.00
19_T	256_A	1.599	1.00
105_G	364_M	1.593	1.00
22_G	253_S	1.591	1.00
415_A	419_I	1.577	1.00
163_A	358_I	1.577	1.00
290_T	294_P	1.575	1.00
255_I	259_I	1.574	1.00
347_H	352_T	1.573	1.00
414_P	431_L	1.567	1.00
49_V	218_A	1.565	1.00
162_N	320_N	1.558	1.00
414_P	417_P	1.550	1.00
155_V	364_M	1.538	1.00
396_R	399_R	1.522	1.00
195_P	199_G	1.510	1.00
205_L	208_V	1.501	1.00
440_P	443_L	1.497	1.00
116_F	150_L	1.495	1.00
196_L	199_G	1.495	1.00
355_V	359_A	1.487	1.00
341_P	345_Q	1.486	1.00
197_F	201_E	1.474	1.00
86_G	89_S	1.470	1.00
326_S	360_S	1.459	1.00
13_L	17_D	1.455	1.00
183_I	310_G	1.454	1.00
56_V	423_L	1.451	1.00
61_G	254_L	1.441	1.00
206_F	209_G	1.431	1.00
235_V	324_I	1.423	1.00
341_P	344_G	1.421	1.00
53_N	222_T	1.419	1.00
159_V	358_I	1.418	1.00
192_A	267_V	1.414	1.00
10_D	351_G	1.411	1.00
164_V	350_Y	1.397	1.00
293_M	298_P	1.391	1.00
331_F	346_I	1.384	1.00
330_A	356_A	1.384	1.00
305_A	309_F	1.379	1.00
17_D	170_G	1.378	1.00
55_V	419_I	1.373	1.00
439_D	443_L	1.366	1.00
392_V	396_R	1.357	1.00
241_N	248_K	1.357	1.00
95_W	453_G	1.353	1.00
112_F	154_A	1.350	1.00
152_F	156_L	1.350	1.00
414_P	418_L	1.344	1.00
109_A	155_V	1.343	1.00
417_P	431_L	1.343	1.00
81_V	389_I	1.339	1.00
293_M	304_G	1.337	1.00
444_A	448_A	1.329	1.00
85_F	89_S	1.327	1.00
112_F	312_V	1.327	1.00
155_V	361_A	1.322	1.00
181_V	185_V	1.320	1.00
74_S	237_E	1.310	1.00
327_S	357_I	1.309	1.00
71_I	83_E	1.289	1.00
428_S	431_L	1.285	1.00
13_L	18_A	1.279	1.00
459_A	462_S	1.278	1.00
188_V	263_A	1.271	1.00
259_I	263_A	1.267	1.00
205_L	209_G	1.266	1.00
392_V	421_I	1.265	1.00
345_Q	354_F	1.264	1.00
242_P	247_P	1.264	1.00
454_T	458_Y	1.259	1.00
158_L	319_L	1.255	1.00
15_L	248_K	1.250	1.00
9_P	331_F	1.245	1.00
61_G	250_I	1.244	1.00
453_G	456_A	1.243	1.00
458_Y	462_S	1.242	1.00
414_P	420_G	1.242	1.00
438_T	441_L	1.229	1.00
47_I	266_T	1.229	1.00
437_R	440_P	1.228	1.00
456_A	459_A	1.227	1.00
456_A	460_H	1.220	1.00
417_P	420_G	1.204	1.00
13_L	170_G	1.202	1.00
60_T	391_N	1.201	1.00
84_I	393_A	1.200	1.00
196_L	200_A	1.199	1.00
201_E	205_L	1.199	1.00
191_G	271_T	1.198	1.00
33_V	111_G	1.195	1.00
245_N	248_K	1.184	1.00
45_A	215_I	1.179	1.00
26_M	257_T	1.178	1.00
401_R	404_M	1.176	1.00
330_A	339_L	1.171	1.00
194_S	198_S	1.170	1.00
79_A	83_E	1.167	1.00
355_V	358_I	1.165	1.00
448_A	452_L	1.164	1.00
187_F	191_G	1.163	1.00
18_A	249_A	1.162	1.00
161_L	172_A	1.151	1.00
108_Y	318_A	1.148	1.00
88_F	460_H	1.144	1.00
195_P	198_S	1.142	1.00
62_L	251_F	1.140	1.00
459_A	463_R	1.139	1.00
148_F	152_F	1.134	1.00
186_V	190_F	1.132	1.00
16_L	20_M	1.132	1.00
402_P	406_R	1.128	1.00
403_D	406_R	1.125	1.00
195_P	200_A	1.121	1.00
444_A	447_A	1.117	1.00
211_G	214_A	1.115	1.00
292_F	297_L	1.114	1.00
299_I	303_G	1.112	1.00
59_F	419_I	1.109	1.00
240_K	245_N	1.107	1.00
98_W	330_A	1.098	1.00
146_A	149_V	1.096	1.00
405_N	411_P	1.087	1.00
81_V	89_S	1.085	1.00
278_A	281_G	1.083	1.00
73_K	79_A	1.081	1.00
12_E	240_K	1.078	1.00
335_R	344_G	1.074	1.00
21_I	235_V	1.073	1.00
388_I	425_L	1.070	1.00
64_Y	77_G	1.068	1.00
451_V	455_A	1.065	1.00
421_I	425_L	1.065	1.00
68_A	80_F	1.064	1.00
23_M	256_A	1.060	1.00
420_G	424_N	1.060	1.00
153_I	157_G	1.059	1.00
171_S	175_I	1.058	1.00
409_E	412_F	1.053	1.00
197_F	200_A	1.053	1.00
51_A	262_L	1.052	1.00
172_A	176_F	1.039	1.00
365_L	368_V	1.037	1.00
420_G	423_L	1.024	1.00
22_G	232_I	1.022	1.00
405_N	409_E	1.021	1.00
395_I	418_L	1.020	1.00
116_F	312_V	1.017	1.00
197_F	270_G	1.013	1.00
159_V	163_A	1.011	1.00
185_V	189_A	1.008	1.00
149_V	153_I	1.007	1.00
362_V	366_A	1.007	1.00
346_I	351_G	1.005	1.00
438_T	442_A	1.004	1.00
425_L	429_V	1.001	1.00
39_A	46_A	1.000	1.00
116_F	120_L	1.000	1.00
412_F	416_P	0.993	1.00
413_Y	431_L	0.990	1.00
195_P	201_E	0.990	1.00
78_Y	332_S	0.988	1.00
70_S	406_R	0.988	1.00
194_S	197_F	0.984	1.00
91_F	95_W	0.983	1.00
73_K	83_E	0.981	1.00
196_L	201_E	0.980	1.00
417_P	421_I	0.970	1.00
83_E	401_R	0.969	1.00
173_E	320_N	0.968	1.00
113_A	150_L	0.964	1.00
156_L	160_A	0.959	1.00
296_G	303_G	0.958	1.00
449_W	456_A	0.958	1.00
176_F	317_T	0.957	1.00
63_S	417_P	0.956	1.00
166_T	324_I	0.956	1.00
404_M	407_P	0.955	1.00
66_E	69_A	0.954	1.00
446_S	450_I	0.952	1.00
23_M	257_T	0.951	1.00
448_A	451_V	0.950	1.00
59_F	416_P	0.949	1.00
107_L	376_G	0.947	1.00
200_A	203_Q	0.947	1.00
415_A	418_L	0.944	1.00
424_N	427_L	0.943	1.00
70_S	404_M	0.941	1.00
446_S	449_W	0.940	1.00
188_V	267_V	0.939	1.00
400_E	403_D	0.938	1.00
413_Y	420_G	0.937	1.00
204_P	207_G	0.927	1.00
194_S	199_G	0.923	1.00
438_T	443_L	0.923	1.00
157_G	316_L	0.922	1.00
188_V	192_A	0.922	1.00
47_I	269_V	0.916	1.00
113_A	151_A	0.913	1.00
266_T	270_G	0.912	1.00
163_A	352_T	0.912	1.00
447_A	453_G	0.909	1.00
181_V	260_V	0.908	1.00
408_Y	411_P	0.905	1.00
427_L	431_L	0.904	1.00
20_M	174_T	0.899	1.00
227_E	383_F	0.897	1.00
252_V	256_A	0.896	1.00
453_G	457_Y	0.896	1.00
323_V	361_A	0.892	1.00
82_R	336_E	0.892	1.00
158_L	320_N	0.890	1.00
273_G	294_P	0.874	1.00
287_E	292_F	0.872	1.00
95_W	339_L	0.869	1.00
388_I	392_V	0.864	1.00
236_T	246_I	0.861	1.00
417_P	424_N	0.859	1.00
354_F	358_I	0.858	1.00
54_G	226_F	0.855	1.00
258_V	262_L	0.854	1.00
145_P	149_V	0.853	1.00
230_D	234_T	0.853	1.00
206_F	210_G	0.849	1.00
107_L	224_I	0.849	1.00
445_L	448_A	0.849	1.00
343_F	355_V	0.848	1.00
274_A	277_L	0.844	1.00
163_A	347_H	0.843	1.00
75_G	79_A	0.837	1.00
201_E	204_P	0.836	1.00
17_D	171_S	0.835	1.00
413_Y	416_P	0.828	1.00
88_F	92_I	0.826	1.00
69_A	407_P	0.824	1.00
12_E	167_A	0.823	1.00
112_F	316_L	0.822	1.00
9_P	328_R	0.820	1.00
457_Y	460_H	0.816	1.00
446_S	453_G	0.815	1.00
27_I	30_G	0.813	1.00
440_P	444_A	0.812	1.00
51_A	55_V	0.811	1.00
458_Y	461_A	0.810	1.00
286_A	290_T	0.809	1.00
58_A	62_L	0.808	1.00
407_P	411_P	0.807	1.00
89_S	389_I	0.807	1.00
192_A	263_A	0.802	1.00
457_Y	461_A	0.797	1.00
197_F	202_F	0.797	1.00
460_H	463_R	0.797	1.00
150_L	153_I	0.796	1.00
427_L	430_V	0.796	1.00
231_L	325_A	0.796	1.00
75_G	78_Y	0.795	1.00
339_L	343_F	0.794	1.00
16_L	174_T	0.790	1.00
67_L	394_V	0.789	1.00
70_S	407_P	0.789	1.00
437_R	443_L	0.788	1.00
113_A	147_A	0.787	1.00
112_F	315_T	0.786	1.00
9_P	238_E	0.786	1.00
393_A	397_L	0.785	1.00
426_V	429_V	0.785	1.00
361_A	365_L	0.783	1.00
160_A	163_A	0.783	1.00
288_A	292_F	0.777	1.00
15_L	249_A	0.776	1.00
86_G	461_A	0.771	1.00
443_L	446_S	0.767	1.00
437_R	441_L	0.765	1.00
394_V	417_P	0.760	1.00
158_L	323_V	0.759	1.00
48_L	215_I	0.759	1.00
441_L	445_L	0.757	1.00
117_L	147_A	0.755	1.00
102_M	363_V	0.753	1.00
395_I	399_R	0.753	1.00
59_F	63_S	0.752	1.00
443_L	447_A	0.751	1.00
203_Q	206_F	0.751	1.00
212_P	215_I	0.748	1.00
180_K	314_S	0.748	1.00
81_V	393_A	0.747	1.00
212_P	216_L	0.742	1.00
394_V	398_R	0.740	1.00
447_A	450_I	0.739	1.00
57_T	229_Y	0.739	1.00
456_A	462_S	0.739	1.00
452_L	456_A	0.736	1.00
450_I	454_T	0.735	1.00
347_H	351_G	0.731	1.00
403_D	409_E	0.730	1.00
455_A	458_Y	0.728	1.00
405_N	408_Y	0.726	1.00
58_A	251_F	0.720	1.00
202_F	206_F	0.718	1.00
97_L	101_Y	0.717	1.00
437_R	442_A	0.716	1.00
199_G	203_Q	0.716	1.00
371_P	374_S	0.714	1.00
381_L	446_S	0.714	1.00
171_S	174_T	0.713	1.00
406_R	409_E	0.708	1.00
204_P	208_V	0.705	1.00
187_F	292_F	0.705	1.00
419_I	423_L	0.704	1.00
106_A	375_A	0.703	1.00
155_V	368_V	0.702	1.00
378_M	382_F	0.702	1.00
402_P	405_N	0.702	1.00
423_L	426_V	0.701	1.00
67_L	80_F	0.699	1.00
418_L	421_I	0.696	1.00
450_I	453_G	0.695	1.00
26_M	253_S	0.694	1.00
408_Y	412_F	0.694	1.00
88_F	454_T	0.694	1.00
16_L	171_S	0.692	1.00
100_A	383_F	0.689	1.00
216_L	426_V	0.688	1.00
19_T	249_A	0.688	1.00
48_L	52_L	0.688	1.00
47_I	51_A	0.687	1.00
421_I	424_N	0.685	1.00
198_S	205_L	0.684	1.00
120_L	123_Y	0.682	1.00
104_A	379_S	0.682	1.00
31_I	264_V	0.681	1.00
441_L	444_A	0.680	1.00
170_G	174_T	0.679	1.00
241_N	247_P	0.679	1.00
50_F	225_A	0.678	1.00
252_V	255_I	0.678	1.00
247_P	250_I	0.677	1.00
188_V	264_V	0.676	1.00
201_E	206_F	0.675	1.00
404_M	409_E	0.675	1.00
292_F	296_G	0.675	1.00
19_T	22_G	0.674	1.00
164_V	168_A	0.674	1.00
110_L	375_A	0.674	1.00
417_P	427_L	0.671	1.00
445_L	449_W	0.670	1.00
391_N	421_I	0.670	1.00
423_L	431_L	0.669	1.00
334_G	343_F	0.669	1.00
233_T	250_I	0.667	1.00
64_Y	390_V	0.667	1.00
12_E	166_T	0.665	1.00
48_L	51_A	0.665	1.00
420_G	427_L	0.662	1.00
382_F	386_S	0.661	1.00
449_W	452_L	0.660	1.00
420_G	429_V	0.659	1.00
227_E	387_F	0.657	1.00
46_A	265_V	0.654	1.00
148_F	368_V	0.654	1.00
217_P	221_L	0.651	1.00
53_N	223_F	0.651	1.00
451_V	454_T	0.651	1.00
342_S	359_A	0.650	1.00
409_E	414_P	0.649	1.00
9_P	12_E	0.647	1.00
162_N	324_I	0.646	1.00
448_A	455_A	0.646	1.00
330_A	359_A	0.646	1.00
457_Y	462_S	0.646	1.00
78_Y	82_R	0.645	1.00
27_I	180_K	0.645	1.00
163_A	350_Y	0.644	1.00
407_P	410_M	0.644	1.00
85_F	393_A	0.641	1.00
152_F	369_A	0.640	1.00
47_I	262_L	0.635	1.00
256_A	260_V	0.633	1.00
417_P	423_L	0.632	1.00
349_R	354_F	0.632	1.00
365_L	369_A	0.632	1.00
162_N	357_I	0.632	1.00
96_M	386_S	0.631	1.00
179_I	310_G	0.629	1.00
67_L	84_I	0.628	1.00
442_A	446_S	0.627	1.00
362_V	365_L	0.626	1.00
154_A	319_L	0.624	1.00
163_A	357_I	0.622	1.00
323_V	327_S	0.621	1.00
119_L	309_F	0.621	1.00
24_G	177_T	0.621	1.00
108_Y	319_L	0.621	1.00
237_E	331_F	0.620	1.00
373_Q	376_G	0.619	1.00
280_A	290_T	0.618	1.00
37_L	373_Q	0.616	1.00
264_V	288_A	0.616	1.00
399_R	414_P	0.616	1.00
271_T	291_S	0.616	1.00
84_I	396_R	0.616	1.00
56_V	59_F	0.615	1.00
401_R	405_N	0.613	1.00
256_A	259_I	0.613	1.00
84_I	397_L	0.613	1.00
277_L	280_A	0.612	1.00
423_L	427_L	0.611	1.00
168_A	171_S	0.610	1.00
447_A	454_T	0.610	1.00
12_E	16_L	0.609	1.00
106_A	367_S	0.607	1.00
444_A	449_W	0.606	1.00
74_S	331_F	0.606	1.00
77_G	230_D	0.606	1.00
417_P	429_V	0.605	1.00
44_P	269_V	0.604	1.00
23_M	177_T	0.603	1.00
292_F	295_T	0.603	1.00
372_T	376_G	0.599	1.00
78_Y	94_G	0.598	1.00
35_T	265_V	0.597	1.00
27_I	260_V	0.597	1.00
118_E	308_V	0.596	1.00
411_P	415_A	0.596	1.00
328_R	331_F	0.596	1.00
103_I	378_M	0.594	1.00
16_L	19_T	0.593	1.00
38_A	42_A	0.593	1.00
440_P	453_G	0.593	1.00
148_F	151_A	0.592	1.00
199_G	202_F	0.592	1.00
116_F	154_A	0.590	1.00
298_P	305_A	0.590	1.00
198_S	206_F	0.587	1.00
104_A	107_L	0.587	1.00
68_A	233_T	0.586	1.00
343_F	356_A	0.585	1.00
61_G	229_Y	0.585	1.00
327_S	356_A	0.585	1.00
165_S	168_A	0.584	1.00
115_N	311_A	0.584	1.00
416_P	419_I	0.583	1.00
200_A	205_L	0.583	1.00
25_A	322_V	0.582	1.00
456_A	461_A	0.582	1.00
113_A	116_F	0.582	1.00
263_A	267_V	0.581	1.00
424_N	431_L	0.580	1.00
403_D	407_P	0.580	1.00
106_A	364_M	0.579	1.00
353_P	356_A	0.578	1.00
457_Y	463_R	0.577	1.00
158_L	316_L	0.577	1.00
63_S	420_G	0.576	1.00
400_E	406_R	0.576	1.00
413_Y	418_L	0.576	1.00
41_I	217_P	0.575	1.00
199_G	270_G	0.575	1.00
202_F	207_G	0.574	1.00
25_A	321_A	0.572	1.00
156_L	159_V	0.571	1.00
406_R	410_M	0.571	1.00
452_L	455_A	0.571	1.00
22_G	26_M	0.569	1.00
37_L	41_I	0.569	1.00
346_I	350_Y	0.569	1.00
424_N	428_S	0.568	1.00
44_P	47_I	0.567	1.00
246_I	250_I	0.567	1.00
422_A	425_L	0.566	1.00
286_A	289_A	0.566	1.00
199_G	205_L	0.566	1.00
412_F	415_A	0.564	1.00
267_V	270_G	0.562	1.00
410_M	416_P	0.561	1.00
45_A	48_L	0.561	1.00
101_Y	322_V	0.560	1.00
326_S	330_A	0.560	1.00
190_F	292_F	0.560	1.00
170_G	320_N	0.560	1.00
342_S	346_I	0.559	1.00
227_E	230_D	0.559	1.00
23_M	26_M	0.558	1.00
168_A	172_A	0.557	1.00
52_L	219_M	0.557	1.00
383_F	386_S	0.556	1.00
65_A	69_A	0.553	1.00
41_I	44_P	0.553	1.00
179_I	183_I	0.552	1.00
102_M	360_S	0.552	1.00
309_F	313_F	0.550	1.00
354_F	357_I	0.550	1.00
169_S	324_I	0.549	1.00
18_A	235_V	0.549	1.00
68_A	246_I	0.549	1.00
194_S	200_A	0.549	1.00
70_S	402_P	0.549	1.00
234_T	325_A	0.548	1.00
109_A	113_A	0.545	1.00
166_T	235_V	0.544	1.00
86_G	90_S	0.544	1.00
31_I	34_L	0.542	1.00
449_W	457_Y	0.541	1.00
446_S	456_A	0.540	1.00
53_N	226_F	0.540	1.00
77_G	234_T	0.539	1.00
395_I	417_P	0.539	1.00
196_L	202_F	0.538	1.00
214_A	217_P	0.538	1.00
119_L	308_V	0.536	1.00
104_A	108_Y	0.534	1.00
204_P	209_G	0.533	1.00
256_A	263_A	0.533	1.00
306_L	310_G	0.533	1.00
63_S	410_M	0.532	1.00
264_V	268_A	0.531	1.00
66_E	411_P	0.531	1.00
159_V	323_V	0.529	1.00
293_M	297_L	0.529	1.00
78_Y	90_S	0.526	1.00
157_G	161_L	0.526	1.00
175_I	178_I	0.524	1.00
60_T	424_N	0.524	1.00
201_E	207_G	0.524	1.00
199_G	204_P	0.524	1.00
242_P	245_N	0.523	1.00
359_A	363_V	0.523	1.00
328_R	353_P	0.523	1.00
410_M	413_Y	0.522	1.00
405_N	412_F	0.521	1.00
243_R	407_P	0.521	1.00
327_S	360_S	0.520	1.00
446_S	460_H	0.517	1.00
38_A	218_A	0.516	1.00
106_A	109_A	0.516	1.00
454_T	457_Y	0.516	1.00
216_L	430_V	0.515	1.00
446_S	451_V	0.515	1.00
111_G	115_N	0.514	1.00
314_S	317_T	0.513	1.00
34_L	376_G	0.512	1.00
198_S	202_F	0.512	1.00
200_A	204_P	0.510	1.00
9_P	74_S	0.510	1.00
230_D	387_F	0.509	1.00
42_A	45_A	0.509	1.00
96_M	385_L	0.508	1.00
11_A	240_K	0.508	1.00
35_T	39_A	0.508	1.00
182_S	185_V	0.508	1.00
35_T	38_A	0.508	1.00
410_M	414_P	0.505	1.00
76_G	233_T	0.504	1.00
404_M	408_Y	0.503	1.00
154_A	158_L	0.502	1.00
154_A	316_L	0.501	1.00
288_A	296_G	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.8522	100	0.32	Contact Map
3giaA	1	0.885	100	0.359	Contact Map
4djkA	2	0.8624	100	0.364	Contact Map
2xq2A	2	0.8419	99	0.857	Contact Map
2jlnA	1	0.8542	98.9	0.862	Contact Map
3dh4A	3	0.8542	98.8	0.869	Contact Map
4xp4A	1	0.9363	98.1	0.894	Contact Map
4us3A	1	0.8296	97.9	0.9	Contact Map
2a65A	2	0.9138	97.8	0.902	Contact Map
4wgvA	2	0.7413	97.4	0.909	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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