Q9HHR4 - HALSA - GREMLIN Contacts

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Q9HHR4 - Vng6268c

UniProt:	Q9HHR4	Sequences: MPQDPSESPSTADTNRTTNDHTRPGPAPTVPAGKNVAELTVKAVLIGLALNVLLLTANMYLGMRSGLTISASIPAAVISMGLFYALRYAGIGGTILENNIVQTMTSAGEALAAGVIFTIAGVTFLDQSINIVETAAVAALGGLLGVLFMIPMRRYLIVDKHEQLPYPEGTACADVLETGSEGDGGVKLISLGFFVSFIYMWLANGMAVMKTTLETAFSAGQTRGFAIGGDFTPALIGVGYIIGPRIAAYVFGGGLVAWMMLIPLLITGGFVPDQAANLTLMGQAHAVWDQYVRYIGAGAMIVGGFYAIISMAGTIRDALASAAAELSGSKSETATQIPRTQRDLSMKVVVLGALAITIALVAIPQVELGVLGGVIAVVAAFLFVAVSAYLVGVVGSSSNPVSGMAVATVLIAALAMKSTGVSDPVVVLLTASVVAIAAAVAGDTSQDLKTGYLLGATPRKQQIAQMVGIAISSVFAGWVLSFFNQAYGIGSETIPAPQAGMMALISEGVLTGSAQWGMILIGAVFAIVLIMMDVPVLPFSVGIYLPITLATPIFLGGLLRAGVDRYVDWRSDDGDGAAKERATYRGRIIAAGLITGEAIMGIVVGGIYVLGIGADEGAPYAVGLASGTQTLLGGVALVALVAVFVGGVIRDPQDT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	655 (574)
Sequences:	2670 (1600)
Seq/√Len:	66.8

HALSA - Q9HHR4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
41_V	45_L	5.210	1.00
188_L	589_I	5.009	1.00
358_I	362_A	4.353	1.00
156_L	388_A	4.106	1.00
36_V	94_T	3.808	1.00
279_T	283_Q	3.767	1.00
207_A	211_T	3.623	1.00
191_L	195_V	3.420	1.00
37_A	94_T	3.373	1.00
244_P	561_A	3.183	1.00
621_A	624_L	3.126	1.00
309_I	313_G	3.028	1.00
620_Y	624_L	3.014	1.00
201_W	206_M	2.839	1.00
618_A	623_G	2.753	1.00
199_Y	202_L	2.737	1.00
357_T	374_V	2.723	1.00
316_R	320_A	2.682	1.00
293_R	297_A	2.629	1.00
52_V	475_F	2.561	1.00
558_L	562_G	2.526	1.00
164_L	392_G	2.521	1.00
84_Y	87_R	2.510	1.00
312_A	316_R	2.510	1.00
345_S	348_V	2.509	1.00
619_P	622_V	2.476	1.00
200_M	204_N	2.474	1.00
207_A	210_K	2.448	1.00
143_L	470_A	2.434	1.00
520_L	524_V	2.423	1.00
208_V	211_T	2.382	1.00
350_V	354_L	2.373	1.00
342_R	459_R	2.291	1.00
333_T	336_Q	2.276	1.00
50_L	78_I	2.247	1.00
147_L	352_G	2.245	1.00
48_L	467_V	2.205	1.00
93_G	101_V	2.180	1.00
470_A	474_V	2.154	1.00
313_G	319_L	2.135	1.00
360_L	373_G	2.113	1.00
301_I	306_Y	2.084	1.00
48_L	471_I	2.073	1.00
619_P	624_L	2.066	1.00
562_G	566_Y	2.035	1.00
474_V	478_W	2.031	1.00
240_Y	586_G	2.030	1.00
285_H	290_Q	2.019	1.00
306_Y	309_I	2.011	1.00
259_M	263_P	2.007	1.00
287_V	290_Q	2.004	1.00
187_K	191_L	2.002	1.00
297_A	301_I	1.991	1.00
251_F	255_L	1.985	1.00
158_V	343_D	1.944	1.00
103_T	461_Q	1.940	1.00
311_M	315_I	1.938	1.00
526_A	530_I	1.934	1.00
524_V	528_V	1.933	1.00
192_G	589_I	1.930	1.00
527_I	531_M	1.926	1.00
131_I	478_W	1.912	1.00
285_H	288_W	1.912	1.00
248_A	252_G	1.911	1.00
288_W	292_V	1.908	1.00
197_F	600_M	1.906	1.00
114_G	117_F	1.898	1.00
384_V	441_A	1.896	1.00
471_I	475_F	1.894	1.00
285_H	289_D	1.881	1.00
361_V	370_V	1.862	1.00
607_I	612_I	1.836	1.00
316_R	319_L	1.833	1.00
271_V	275_A	1.832	1.00
39_L	463_I	1.811	1.00
294_Y	298_G	1.793	1.00
313_G	320_A	1.781	1.00
310_S	314_T	1.769	1.00
391_V	401_V	1.750	1.00
194_F	198_I	1.748	1.00
114_G	121_G	1.746	1.00
283_Q	286_A	1.742	1.00
306_Y	310_S	1.741	1.00
513_S	516_W	1.739	1.00
620_Y	623_G	1.737	1.00
208_V	212_T	1.726	1.00
360_L	433_V	1.723	1.00
52_V	471_I	1.719	1.00
451_G	461_Q	1.705	0.99
138_A	473_S	1.702	0.99
153_R	343_D	1.700	0.99
198_I	202_L	1.683	0.99
62_G	116_I	1.680	0.99
286_A	289_D	1.676	0.99
289_D	294_Y	1.667	0.99
153_R	448_L	1.663	0.99
313_G	316_R	1.660	0.99
114_G	124_F	1.660	0.99
45_L	86_L	1.658	0.99
503_A	507_E	1.653	0.99
516_W	520_L	1.648	0.99
619_P	623_G	1.647	0.99
143_L	466_M	1.646	0.99
196_S	597_E	1.641	0.99
309_I	312_A	1.638	0.99
306_Y	313_G	1.621	0.99
181_E	184_G	1.618	0.99
206_M	210_K	1.606	0.99
285_H	298_G	1.603	0.99
288_W	291_Y	1.597	0.99
561_A	565_R	1.596	0.99
116_I	121_G	1.590	0.99
312_A	315_I	1.567	0.99
114_G	120_A	1.564	0.99
306_Y	311_M	1.558	0.99
272_P	275_A	1.558	0.99
43_A	100_I	1.544	0.99
312_A	319_L	1.542	0.99
315_I	318_A	1.542	0.99
169_G	446_Q	1.540	0.99
357_T	361_V	1.531	0.99
117_F	120_A	1.531	0.99
523_A	527_I	1.526	0.99
242_I	246_I	1.519	0.99
370_V	374_V	1.515	0.99
46_I	82_L	1.514	0.99
349_V	448_L	1.514	0.99
298_G	301_I	1.503	0.99
255_L	260_M	1.500	0.99
84_Y	94_T	1.495	0.99
294_Y	297_A	1.486	0.99
221_Q	230_D	1.483	0.99
313_G	318_A	1.480	0.99
260_M	264_L	1.478	0.99
255_L	259_M	1.475	0.99
289_D	298_G	1.475	0.99
99_N	176_L	1.472	0.99
320_A	324_A	1.471	0.98
256_V	260_M	1.461	0.98
80_M	84_Y	1.459	0.98
116_I	120_A	1.450	0.98
189_I	203_A	1.447	0.98
206_M	211_T	1.441	0.98
253_G	538_P	1.431	0.98
95_I	176_L	1.426	0.98
98_N	180_S	1.422	0.98
285_H	291_Y	1.421	0.98
373_G	433_V	1.420	0.98
169_G	450_T	1.420	0.98
306_Y	315_I	1.418	0.98
440_V	469_I	1.417	0.98
379_A	411_I	1.410	0.98
388_A	442_G	1.410	0.98
309_I	320_A	1.406	0.98
293_R	298_G	1.405	0.98
100_I	464_A	1.401	0.98
408_T	434_V	1.400	0.98
54_L	75_A	1.390	0.98
140_L	356_I	1.388	0.98
55_L	59_M	1.387	0.98
286_A	297_A	1.384	0.98
213_L	218_S	1.380	0.98
143_L	356_I	1.379	0.98
113_A	116_I	1.377	0.98
305_F	309_I	1.375	0.98
111_L	114_G	1.370	0.98
562_G	567_V	1.359	0.97
301_I	309_I	1.351	0.97
50_L	79_S	1.349	0.97
186_V	190_S	1.346	0.97
547_I	550_A	1.343	0.97
154_R	346_M	1.341	0.97
466_M	470_A	1.338	0.97
315_I	320_A	1.337	0.97
214_E	217_F	1.335	0.97
338_P	341_Q	1.334	0.97
301_I	315_I	1.314	0.97
271_V	274_Q	1.314	0.97
197_F	201_W	1.312	0.97
116_I	124_F	1.312	0.97
352_G	466_M	1.312	0.97
275_A	278_L	1.299	0.97
43_A	464_A	1.298	0.97
521_I	524_V	1.293	0.97
290_Q	298_G	1.291	0.97
117_F	121_G	1.291	0.97
82_L	85_A	1.290	0.97
523_A	526_A	1.290	0.97
135_A	474_V	1.276	0.96
93_G	98_N	1.270	0.96
252_G	538_P	1.270	0.96
115_V	120_A	1.269	0.96
413_A	427_V	1.266	0.96
549_L	552_P	1.264	0.96
285_H	297_A	1.254	0.96
520_L	523_A	1.249	0.96
560_R	564_D	1.239	0.96
618_A	621_A	1.236	0.96
41_V	86_L	1.234	0.96
316_R	322_A	1.234	0.96
112_A	116_I	1.230	0.95
432_S	436_I	1.228	0.95
300_M	306_Y	1.224	0.95
561_A	566_Y	1.224	0.95
209_M	212_T	1.223	0.95
375_I	415_A	1.221	0.95
112_A	121_G	1.220	0.95
221_Q	231_F	1.216	0.95
261_L	292_V	1.207	0.95
309_I	315_I	1.203	0.95
309_I	314_T	1.201	0.95
146_V	469_I	1.200	0.95
427_V	431_A	1.196	0.95
38_E	457_T	1.196	0.95
291_Y	294_Y	1.191	0.95
50_L	82_L	1.187	0.94
592_G	596_G	1.185	0.94
306_Y	314_T	1.181	0.94
213_L	217_F	1.180	0.94
192_G	592_G	1.179	0.94
115_V	121_G	1.176	0.94
310_S	315_I	1.175	0.94
113_A	117_F	1.173	0.94
103_T	450_T	1.173	0.94
75_A	105_T	1.171	0.94
286_A	291_Y	1.161	0.94
104_M	464_A	1.159	0.94
514_A	518_M	1.157	0.94
106_S	450_T	1.151	0.93
284_A	288_W	1.149	0.93
482_F	606_G	1.148	0.93
347_K	351_L	1.148	0.93
47_G	104_M	1.147	0.93
344_L	348_V	1.147	0.93
225_F	230_D	1.140	0.93
590_A	593_L	1.137	0.93
96_L	455_G	1.129	0.93
173_A	450_T	1.129	0.93
301_I	313_G	1.123	0.93
244_P	248_A	1.122	0.93
263_P	269_G	1.119	0.92
83_F	101_V	1.118	0.92
286_A	290_Q	1.118	0.92
222_T	230_D	1.115	0.92
98_N	101_V	1.112	0.92
600_M	604_V	1.110	0.92
294_Y	300_M	1.107	0.92
136_A	140_L	1.101	0.92
505_I	602_I	1.100	0.92
603_V	607_I	1.100	0.92
310_S	313_G	1.099	0.92
287_V	291_Y	1.099	0.92
284_A	289_D	1.096	0.92
247_A	560_R	1.096	0.92
290_Q	294_Y	1.093	0.92
239_G	556_G	1.089	0.91
203_A	211_T	1.089	0.91
286_A	294_Y	1.088	0.91
194_F	197_F	1.086	0.91
343_D	448_L	1.084	0.91
340_T	457_T	1.082	0.91
409_V	427_V	1.080	0.91
140_L	433_V	1.076	0.91
288_W	294_Y	1.072	0.91
193_F	592_G	1.070	0.91
191_L	194_F	1.068	0.91
139_A	474_V	1.068	0.91
230_D	233_P	1.067	0.91
104_M	468_G	1.065	0.91
592_G	595_T	1.065	0.91
233_P	236_I	1.064	0.90
348_V	462_Q	1.063	0.90
618_A	622_V	1.060	0.90
515_Q	518_M	1.059	0.90
54_L	109_E	1.057	0.90
550_A	555_L	1.056	0.90
554_F	557_G	1.055	0.90
114_G	119_I	1.055	0.90
112_A	117_F	1.050	0.90
301_I	311_M	1.045	0.90
25_G	30_V	1.042	0.90
152_M	384_V	1.041	0.89
285_H	294_Y	1.030	0.89
312_A	320_A	1.028	0.89
346_M	350_V	1.021	0.89
313_G	317_D	1.021	0.89
265_L	268_G	1.020	0.89
42_K	97_E	1.015	0.88
459_R	463_I	1.013	0.88
289_D	297_A	1.011	0.88
297_A	300_M	1.010	0.88
284_A	290_Q	1.009	0.88
50_L	176_L	1.005	0.88
87_R	92_G	1.004	0.88
140_L	360_L	1.004	0.88
332_E	338_P	1.003	0.88
46_I	86_L	1.002	0.88
412_A	415_A	1.002	0.88
548_T	551_T	1.000	0.88
410_L	505_I	0.995	0.87
291_Y	298_G	0.991	0.87
207_A	212_T	0.985	0.87
222_T	228_G	0.984	0.87
258_W	262_I	0.981	0.87
408_T	435_A	0.981	0.87
311_M	314_T	0.979	0.86
519_I	522_G	0.978	0.86
42_K	93_G	0.972	0.86
515_Q	519_I	0.970	0.86
140_L	363_I	0.969	0.86
350_V	362_A	0.967	0.86
302_V	306_Y	0.965	0.86
403_G	434_V	0.961	0.85
384_V	437_A	0.959	0.85
608_Y	613_G	0.955	0.85
113_A	119_I	0.954	0.85
548_T	552_P	0.953	0.85
606_G	610_L	0.952	0.85
512_G	582_A	0.949	0.85
309_I	317_D	0.948	0.85
294_Y	306_Y	0.946	0.84
84_Y	88_Y	0.944	0.84
112_A	120_A	0.942	0.84
215_T	267_T	0.941	0.84
401_V	442_G	0.941	0.84
46_I	79_S	0.936	0.84
548_T	553_I	0.935	0.84
45_L	49_A	0.934	0.84
80_M	93_G	0.933	0.84
307_A	310_S	0.929	0.83
228_G	551_T	0.927	0.83
193_F	599_I	0.925	0.83
112_A	115_V	0.924	0.83
354_L	358_I	0.924	0.83
222_T	231_F	0.924	0.83
376_A	430_T	0.924	0.83
181_E	187_K	0.923	0.83
315_I	319_L	0.920	0.83
44_V	467_V	0.920	0.83
43_A	47_G	0.919	0.83
132_V	136_A	0.919	0.83
34_K	340_T	0.918	0.83
311_M	319_L	0.916	0.82
233_P	593_L	0.914	0.82
148_F	381_F	0.911	0.82
297_A	306_Y	0.906	0.82
99_N	454_L	0.905	0.82
359_A	382_L	0.904	0.82
131_I	590_A	0.901	0.81
254_G	550_A	0.899	0.81
580_E	584_Y	0.894	0.81
71_A	109_E	0.893	0.81
432_S	440_V	0.892	0.81
293_R	301_I	0.889	0.81
113_A	120_A	0.888	0.80
143_L	474_V	0.887	0.80
54_L	105_T	0.885	0.80
212_T	231_F	0.885	0.80
359_A	363_I	0.884	0.80
441_A	446_Q	0.881	0.80
433_V	479_V	0.881	0.80
190_S	194_F	0.879	0.80
201_W	600_M	0.878	0.80
528_V	532_M	0.872	0.79
470_A	475_F	0.869	0.79
146_V	448_L	0.869	0.79
184_G	351_L	0.866	0.79
444_T	448_L	0.865	0.79
309_I	316_R	0.863	0.79
216_A	220_G	0.862	0.78
299_A	306_Y	0.862	0.78
289_D	293_R	0.861	0.78
567_V	606_G	0.858	0.78
482_F	486_A	0.856	0.78
347_K	350_V	0.856	0.78
77_V	179_G	0.852	0.78
599_I	603_V	0.851	0.78
313_G	322_A	0.851	0.78
615_D	622_V	0.850	0.78
148_F	437_A	0.850	0.78
375_I	416_M	0.848	0.77
238_V	590_A	0.845	0.77
288_W	298_G	0.843	0.77
307_A	311_M	0.843	0.77
288_W	293_R	0.842	0.77
204_N	604_V	0.842	0.77
111_L	115_V	0.841	0.77
285_H	293_R	0.836	0.76
248_A	554_F	0.834	0.76
260_M	263_P	0.834	0.76
258_W	288_W	0.834	0.76
189_I	193_F	0.831	0.76
252_G	529_L	0.830	0.76
28_P	32_A	0.829	0.76
317_D	354_L	0.827	0.76
451_G	458_P	0.824	0.75
63_M	499_A	0.823	0.75
56_T	59_M	0.822	0.75
257_A	543_I	0.821	0.75
311_M	318_A	0.820	0.75
217_F	221_Q	0.818	0.75
498_Q	544_Y	0.817	0.75
456_A	461_Q	0.811	0.74
88_Y	328_G	0.808	0.74
39_L	44_V	0.807	0.74
135_A	331_S	0.807	0.74
145_G	153_R	0.805	0.74
504_L	511_T	0.805	0.74
342_R	457_T	0.805	0.74
206_M	212_T	0.804	0.73
183_D	187_K	0.804	0.73
314_T	319_L	0.803	0.73
412_A	430_T	0.802	0.73
412_A	427_V	0.795	0.73
32_A	36_V	0.793	0.72
37_A	41_V	0.793	0.72
116_I	123_T	0.791	0.72
202_L	346_M	0.791	0.72
286_A	298_G	0.790	0.72
273_D	521_I	0.790	0.72
293_R	300_M	0.787	0.72
287_V	298_G	0.787	0.72
606_G	612_I	0.787	0.72
45_L	82_L	0.786	0.72
240_Y	563_V	0.785	0.72
354_L	362_A	0.782	0.71
607_I	611_G	0.780	0.71
25_G	28_P	0.780	0.71
306_Y	319_L	0.780	0.71
248_A	561_A	0.778	0.71
306_Y	318_A	0.778	0.71
298_G	518_M	0.777	0.71
615_D	620_Y	0.774	0.71
446_Q	544_Y	0.773	0.71
599_I	605_G	0.772	0.70
83_F	87_R	0.770	0.70
168_E	193_F	0.770	0.70
217_F	474_V	0.770	0.70
615_D	618_A	0.770	0.70
309_I	318_A	0.769	0.70
106_S	109_E	0.767	0.70
41_V	44_V	0.767	0.70
521_I	528_V	0.766	0.70
221_Q	226_A	0.766	0.70
263_P	267_T	0.766	0.70
131_I	477_G	0.766	0.70
589_I	593_L	0.763	0.70
451_G	602_I	0.763	0.70
485_Q	521_I	0.762	0.69
137_V	532_M	0.762	0.69
131_I	135_A	0.759	0.69
79_S	101_V	0.758	0.69
561_A	564_D	0.758	0.69
287_V	294_Y	0.757	0.69
49_A	82_L	0.754	0.69
32_A	35_N	0.753	0.69
285_H	301_I	0.752	0.68
112_A	124_F	0.750	0.68
582_A	587_R	0.748	0.68
39_L	460_K	0.746	0.68
55_L	106_S	0.746	0.68
109_E	595_T	0.744	0.68
251_F	557_G	0.742	0.67
563_V	567_V	0.739	0.67
146_V	466_M	0.738	0.67
300_M	406_V	0.738	0.67
271_V	276_A	0.736	0.67
311_M	320_A	0.735	0.67
222_T	225_F	0.733	0.66
185_G	188_L	0.733	0.66
265_L	291_Y	0.733	0.66
196_S	593_L	0.732	0.66
242_I	497_P	0.729	0.66
117_F	124_F	0.729	0.66
122_V	483_F	0.728	0.66
61_L	68_T	0.728	0.66
48_L	355_A	0.727	0.66
314_T	318_A	0.725	0.66
39_L	43_A	0.725	0.66
103_T	447_D	0.725	0.66
255_L	375_I	0.722	0.65
200_M	203_A	0.721	0.65
301_I	305_F	0.720	0.65
403_G	438_A	0.720	0.65
225_F	232_T	0.719	0.65
375_I	411_I	0.717	0.65
102_Q	450_T	0.716	0.65
107_A	472_S	0.715	0.65
320_A	323_A	0.714	0.64
326_L	329_S	0.713	0.64
57_A	602_I	0.712	0.64
196_S	200_M	0.712	0.64
121_G	124_F	0.711	0.64
408_T	438_A	0.709	0.64
375_I	378_V	0.709	0.64
525_F	539_F	0.708	0.64
185_G	189_I	0.707	0.64
178_T	323_A	0.707	0.64
118_T	122_V	0.707	0.64
565_R	568_D	0.707	0.64
307_A	483_F	0.706	0.64
315_I	322_A	0.706	0.64
194_F	354_L	0.706	0.64
159_D	162_E	0.705	0.63
261_L	264_L	0.705	0.63
247_A	557_G	0.704	0.63
305_F	308_I	0.704	0.63
546_P	552_P	0.703	0.63
443_D	447_D	0.702	0.63
54_L	108_G	0.702	0.63
372_G	416_M	0.701	0.63
555_L	558_L	0.701	0.63
469_I	473_S	0.701	0.63
222_T	277_N	0.701	0.63
52_V	55_L	0.700	0.63
371_L	375_I	0.700	0.63
298_G	545_L	0.699	0.63
399_N	442_G	0.699	0.63
252_G	520_L	0.697	0.63
235_L	549_L	0.697	0.63
338_P	452_Y	0.696	0.62
521_I	531_M	0.695	0.62
143_L	521_I	0.695	0.62
112_A	123_T	0.694	0.62
489_I	600_M	0.693	0.62
299_A	381_F	0.693	0.62
265_L	269_G	0.693	0.62
49_A	323_A	0.691	0.62
242_I	590_A	0.691	0.62
52_V	88_Y	0.691	0.62
229_G	478_W	0.690	0.62
524_V	532_M	0.689	0.62
124_F	503_A	0.687	0.61
216_A	226_A	0.687	0.61
252_G	350_V	0.687	0.61
405_A	437_A	0.687	0.61
149_M	445_S	0.686	0.61
64_R	511_T	0.686	0.61
375_I	379_A	0.685	0.61
142_G	469_I	0.683	0.61
217_F	220_G	0.683	0.61
101_V	260_M	0.682	0.61
306_Y	312_A	0.682	0.61
172_C	450_T	0.682	0.61
521_I	525_F	0.682	0.61
527_I	599_I	0.681	0.61
193_F	595_T	0.680	0.61
140_L	477_G	0.680	0.61
111_L	116_I	0.680	0.61
464_A	602_I	0.678	0.60
580_E	583_T	0.678	0.60
37_A	96_L	0.677	0.60
301_I	304_G	0.676	0.60
196_S	497_P	0.676	0.60
516_W	519_I	0.676	0.60
474_V	562_G	0.676	0.60
172_C	176_L	0.675	0.60
357_T	377_V	0.674	0.60
62_G	67_L	0.673	0.60
583_T	602_I	0.673	0.60
374_V	378_V	0.671	0.60
294_Y	301_I	0.669	0.59
375_I	412_A	0.668	0.59
402_S	499_A	0.668	0.59
490_G	493_T	0.668	0.59
120_A	124_F	0.668	0.59
226_A	231_F	0.668	0.59
93_G	180_S	0.667	0.59
103_T	107_A	0.666	0.59
355_A	362_A	0.664	0.59
229_G	233_P	0.664	0.59
287_V	293_R	0.664	0.59
523_A	580_E	0.661	0.58
409_V	434_V	0.660	0.58
351_L	355_A	0.660	0.58
100_I	456_A	0.660	0.58
473_S	509_V	0.659	0.58
404_M	503_A	0.659	0.58
344_L	370_V	0.658	0.58
203_A	208_V	0.657	0.58
615_D	619_P	0.657	0.58
238_V	553_I	0.656	0.58
590_A	594_I	0.656	0.58
521_I	526_A	0.656	0.58
341_Q	471_I	0.656	0.58
213_L	227_I	0.656	0.58
187_K	524_V	0.656	0.58
77_V	595_T	0.655	0.58
104_M	384_V	0.651	0.57
604_V	610_L	0.650	0.57
29_T	49_A	0.649	0.57
111_L	144_L	0.649	0.57
300_M	407_A	0.648	0.57
452_Y	560_R	0.648	0.57
308_I	331_S	0.647	0.57
116_I	122_V	0.647	0.57
114_G	123_T	0.645	0.57
291_Y	297_A	0.644	0.56
353_A	357_T	0.644	0.56
113_A	121_G	0.644	0.56
45_L	48_L	0.644	0.56
71_A	595_T	0.643	0.56
79_S	98_N	0.641	0.56
168_E	446_Q	0.641	0.56
144_L	437_A	0.640	0.56
210_K	213_L	0.639	0.56
285_H	306_Y	0.638	0.56
229_G	551_T	0.637	0.56
72_S	172_C	0.637	0.56
403_G	408_T	0.637	0.56
196_S	596_G	0.637	0.56
170_T	453_L	0.637	0.56
319_L	322_A	0.637	0.56
481_S	485_Q	0.635	0.55
144_L	303_G	0.634	0.55
132_V	494_I	0.633	0.55
136_A	359_A	0.633	0.55
251_F	551_T	0.632	0.55
301_I	602_I	0.631	0.55
312_A	323_A	0.631	0.55
524_V	527_I	0.631	0.55
221_Q	225_F	0.630	0.55
296_G	301_I	0.629	0.55
58_N	64_R	0.629	0.55
375_I	532_M	0.628	0.55
274_Q	277_N	0.627	0.54
115_V	119_I	0.627	0.54
391_V	442_G	0.626	0.54
95_I	177_E	0.626	0.54
171_A	241_I	0.626	0.54
33_G	350_V	0.626	0.54
535_P	538_P	0.626	0.54
198_I	350_V	0.626	0.54
182_G	186_V	0.626	0.54
434_V	438_A	0.625	0.54
284_A	294_Y	0.625	0.54
55_L	105_T	0.624	0.54
28_P	31_P	0.624	0.54
76_A	102_Q	0.623	0.54
33_G	83_F	0.623	0.54
69_I	109_E	0.623	0.54
345_S	524_V	0.620	0.54
213_L	216_A	0.618	0.53
375_I	538_P	0.618	0.53
257_A	261_L	0.618	0.53
300_M	304_G	0.617	0.53
351_L	354_L	0.616	0.53
151_P	314_T	0.616	0.53
251_F	359_A	0.616	0.53
380_A	463_I	0.615	0.53
540_S	544_Y	0.615	0.53
547_I	552_P	0.613	0.53
264_L	268_G	0.612	0.53
240_Y	593_L	0.612	0.53
320_A	565_R	0.612	0.53
296_G	300_M	0.612	0.53
33_G	37_A	0.611	0.53
127_Q	590_A	0.610	0.52
159_D	345_S	0.610	0.52
582_A	585_R	0.610	0.52
187_K	325_E	0.610	0.52
399_N	598_A	0.610	0.52
148_F	489_I	0.608	0.52
405_A	503_A	0.608	0.52
564_D	583_T	0.608	0.52
233_P	237_G	0.607	0.52
232_T	584_Y	0.606	0.52
525_F	528_V	0.606	0.52
279_T	374_V	0.605	0.52
322_A	325_E	0.605	0.52
223_R	230_D	0.604	0.52
376_A	412_A	0.604	0.52
59_M	602_I	0.602	0.52
310_S	316_R	0.601	0.51
251_F	540_S	0.601	0.51
507_E	511_T	0.601	0.51
316_R	324_A	0.601	0.51
352_G	356_I	0.599	0.51
260_M	456_A	0.597	0.51
564_D	568_D	0.597	0.51
318_A	322_A	0.596	0.51
431_A	515_Q	0.595	0.51
529_L	533_D	0.594	0.51
449_K	452_Y	0.593	0.50
67_L	236_I	0.593	0.50
49_A	88_Y	0.593	0.50
201_W	501_M	0.592	0.50
125_L	504_L	0.592	0.50
579_K	582_A	0.591	0.50
171_A	590_A	0.591	0.50
38_E	52_V	0.591	0.50
337_I	455_G	0.590	0.50
300_M	311_M	0.590	0.50
155_Y	392_G	0.589	0.50
263_P	268_G	0.588	0.50
236_I	545_L	0.588	0.50
291_Y	295_I	0.586	0.50
113_A	122_V	0.586	0.50
305_F	315_I	0.586	0.50
69_I	304_G	0.585	0.50
284_A	292_V	0.585	0.50
484_N	487_Y	0.584	0.49
564_D	579_K	0.584	0.49
516_W	524_V	0.582	0.49
448_L	458_P	0.582	0.49
588_I	602_I	0.582	0.49
275_A	279_T	0.582	0.49
206_M	228_G	0.581	0.49
136_A	613_G	0.581	0.49
179_G	186_V	0.581	0.49
448_L	456_A	0.580	0.49
112_A	118_T	0.579	0.49
444_T	465_Q	0.579	0.49
112_A	436_I	0.579	0.49
253_G	505_I	0.578	0.49
238_V	545_L	0.576	0.48
550_A	553_I	0.575	0.48
188_L	585_R	0.575	0.48
118_T	121_G	0.574	0.48
58_N	62_G	0.573	0.48
266_I	269_G	0.572	0.48
462_Q	465_Q	0.572	0.48
94_T	97_E	0.570	0.48
199_Y	375_I	0.570	0.48
485_Q	606_G	0.569	0.48
80_M	180_S	0.568	0.48
411_I	623_G	0.568	0.48
76_A	176_L	0.567	0.47
57_A	71_A	0.567	0.47
403_G	435_A	0.567	0.47
305_F	313_G	0.567	0.47
258_W	541_V	0.566	0.47
144_L	377_V	0.566	0.47
98_N	150_I	0.565	0.47
63_M	118_T	0.565	0.47
379_A	408_T	0.563	0.47
153_R	458_P	0.563	0.47
401_V	509_V	0.563	0.47
45_L	414_L	0.562	0.47
286_A	301_I	0.561	0.47
43_A	359_A	0.560	0.47
225_F	233_P	0.559	0.46
169_G	392_G	0.559	0.46
111_L	476_A	0.559	0.46
146_V	445_S	0.558	0.46
168_E	544_Y	0.557	0.46
212_T	505_I	0.556	0.46
257_A	260_M	0.556	0.46
151_P	441_A	0.556	0.46
611_G	614_A	0.555	0.46
414_L	524_V	0.554	0.46
141_G	432_S	0.553	0.46
217_F	225_F	0.553	0.46
272_P	374_V	0.553	0.46
189_I	207_A	0.552	0.46
449_K	522_G	0.552	0.46
89_A	92_G	0.550	0.45
76_A	172_C	0.549	0.45
601_G	614_A	0.549	0.45
139_A	473_S	0.549	0.45
29_T	177_E	0.548	0.45
50_L	53_L	0.547	0.45
116_I	119_I	0.546	0.45
293_R	498_Q	0.546	0.45
134_T	138_A	0.546	0.45
361_V	369_G	0.546	0.45
222_T	226_A	0.545	0.45
294_Y	299_A	0.544	0.45
136_A	139_A	0.543	0.45
246_I	250_V	0.542	0.44
273_D	276_A	0.542	0.44
257_A	292_V	0.541	0.44
567_V	604_V	0.541	0.44
295_I	544_Y	0.540	0.44
81_G	85_A	0.539	0.44
98_N	447_D	0.539	0.44
594_I	597_E	0.538	0.44
198_I	252_G	0.537	0.44
88_Y	456_A	0.536	0.44
79_S	176_L	0.536	0.44
204_N	208_V	0.535	0.44
32_A	96_L	0.535	0.44
606_G	609_V	0.535	0.44
25_G	29_T	0.534	0.44
115_V	124_F	0.534	0.44
38_E	592_G	0.533	0.43
240_Y	590_A	0.532	0.43
27_A	30_V	0.532	0.43
184_G	255_L	0.532	0.43
276_A	410_L	0.532	0.43
57_A	358_I	0.532	0.43
61_L	605_G	0.531	0.43
176_L	454_L	0.531	0.43
389_Y	393_V	0.530	0.43
293_R	306_Y	0.529	0.43
103_T	448_L	0.529	0.43
199_Y	203_A	0.529	0.43
173_A	499_A	0.528	0.43
178_T	604_V	0.528	0.43
113_A	482_F	0.528	0.43
284_A	287_V	0.528	0.43
62_G	499_A	0.528	0.43
234_A	597_E	0.527	0.43
157_I	180_S	0.527	0.43
86_L	94_T	0.527	0.43
76_A	457_T	0.526	0.43
345_S	459_R	0.526	0.43
467_V	581_R	0.526	0.43
132_V	256_V	0.525	0.42
298_G	304_G	0.525	0.42
359_A	593_L	0.524	0.42
118_T	125_L	0.523	0.42
79_S	443_D	0.522	0.42
378_V	382_L	0.521	0.42
305_F	531_M	0.521	0.42
159_D	453_L	0.520	0.42
111_L	120_A	0.519	0.42
43_A	104_M	0.518	0.42
291_Y	300_M	0.518	0.42
256_V	525_F	0.517	0.42
70_S	74_P	0.517	0.42
371_L	425_V	0.517	0.42
96_L	148_F	0.516	0.41
198_I	361_V	0.515	0.41
405_A	431_A	0.515	0.41
113_A	123_T	0.515	0.41
362_A	370_V	0.515	0.41
174_D	178_T	0.514	0.41
441_A	486_A	0.513	0.41
227_I	489_I	0.513	0.41
508_G	511_T	0.513	0.41
536_V	547_I	0.512	0.41
530_I	533_D	0.512	0.41
448_L	460_K	0.512	0.41
564_D	567_V	0.511	0.41
381_F	477_G	0.511	0.41
323_A	358_I	0.511	0.41
297_A	310_S	0.510	0.41
298_G	306_Y	0.509	0.41
56_T	479_V	0.509	0.41
188_L	231_F	0.509	0.41
63_M	482_F	0.509	0.41
373_G	379_A	0.508	0.41
117_F	498_Q	0.508	0.41
279_T	324_A	0.507	0.40
74_P	499_A	0.507	0.40
88_Y	374_V	0.506	0.40
317_D	532_M	0.506	0.40
205_G	604_V	0.505	0.40
413_A	417_K	0.505	0.40
332_E	336_Q	0.505	0.40
49_A	615_D	0.504	0.40
61_L	65_S	0.504	0.40
195_V	279_T	0.504	0.40
538_P	541_V	0.503	0.40
136_A	363_I	0.503	0.40
268_G	591_A	0.503	0.40
602_I	605_G	0.502	0.40
98_N	454_L	0.502	0.40
309_I	363_I	0.500	0.40
405_A	540_S	0.500	0.40

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ui9I	1	0.0183	62.6	0.976	Contact Map
4k1cA	4	0.2672	59.4	0.977	Contact Map
3wdoA	1	0.0977	28.2	0.981	Contact Map
2cfqA	1	0.3328	27.3	0.981	Contact Map
4tkrA	2	0.2733	23.4	0.982	Contact Map
3rlbA	1	0.2611	22.3	0.982	Contact Map
4kjrA	3	0.2244	18.1	0.983	Contact Map
4gyiA	1	0.0107	18	0.983	Contact Map
1so2A	2	0.0382	16.1	0.983	Contact Map
2kluA	1	0.0626	16	0.983	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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