GREMLIN Database
Q9HHQ5 - sn-glycerol-3-phosphate transport system ATP-binding
UniProt: Q9HHQ5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 379 (323)
Sequences: 18255 (13150)
Seq/√Len: 731.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
217_A221_Q4.0941.00
59_T66_D3.8061.00
33_V202_G3.6541.00
120_A125_T3.6121.00
304_A320_C3.5121.00
30_E204_R3.4161.00
5_T25_D3.3981.00
8_D21_G3.3891.00
7_T59_T3.2891.00
17_A20_D3.0901.00
112_E116_A3.0601.00
307_T321_T2.8331.00
214_Q228_N2.7621.00
32_L206_A2.5311.00
107_S110_E2.5071.00
7_T61_R2.4881.00
218_P221_Q2.4701.00
10_T17_A2.4681.00
20_D212_T2.4521.00
127_L130_R2.4231.00
12_H17_A2.3931.00
10_T57_A2.3901.00
5_T61_R2.3601.00
93_A129_D2.3581.00
93_A97_T2.3351.00
114_R152_E2.3281.00
93_A116_A2.2981.00
93_A112_E2.2711.00
6_L9_L2.2691.00
27_L30_E2.2351.00
8_D23_D2.1701.00
229_Q280_T2.1631.00
61_R66_D2.1321.00
123_G172_H2.1301.00
63_G154_S2.0991.00
179_K183_E2.0951.00
315_Q330_K2.0371.00
76_D154_S2.0291.00
11_K48_L2.0111.00
10_T21_G1.9511.00
4_I155_V1.9411.00
206_A216_V1.8871.00
119_A128_L1.8801.00
114_R117_D1.8611.00
209_N214_Q1.8451.00
206_A213_V1.8411.00
19_V48_L1.8281.00
110_E113_D1.8221.00
113_D117_D1.7921.00
48_L55_A1.7781.00
49_I189_V1.7661.00
9_L55_A1.7191.00
11_K56_T1.6881.00
65_T154_S1.6791.00
109_A113_D1.6511.00
97_T115_V1.6481.00
65_T70_S1.6351.00
66_D69_D1.5911.00
305_R321_T1.5841.00
47_R53_E1.5741.00
158_L188_T1.5711.00
11_K53_E1.5581.00
321_T324_D1.5561.00
106_Y110_E1.5481.00
93_A115_V1.5421.00
199_M220_Q1.5421.00
259_E262_A1.5351.00
62_I67_V1.5281.00
118_A150_V1.5161.00
116_A120_A1.5081.00
110_E114_R1.4951.00
67_V70_S1.4911.00
46_L191_V1.4911.00
229_Q242_L1.4821.00
263_H266_P1.4821.00
122_L146_G1.4711.00
48_L60_I1.4681.00
32_L216_V1.4641.00
6_L49_I1.4591.00
220_Q224_D1.4351.00
97_T111_I1.4261.00
22_I45_T1.4191.00
246_R278_R1.4111.00
320_C329_V1.4091.00
6_L24_L1.3931.00
91_T94_E1.3791.00
274_L277_R1.3661.00
106_Y111_I1.3651.00
12_H56_T1.3651.00
90_M98_F1.3491.00
55_A60_I1.3361.00
256_A259_E1.3251.00
117_D152_E1.3231.00
10_T20_D1.3211.00
117_D120_A1.3211.00
317_L330_K1.3101.00
229_Q233_G1.3081.00
6_L45_T1.3021.00
309_R318_L1.2981.00
91_T131_T1.2921.00
242_L280_T1.2821.00
233_G242_L1.2811.00
260_G263_H1.2801.00
94_E101_Q1.2741.00
116_A128_L1.2561.00
19_V45_T1.2451.00
181_H188_T1.2301.00
89_H133_D1.2261.00
221_Q225_F1.2181.00
7_T23_D1.2151.00
111_I115_V1.2101.00
59_T68_T1.2071.00
244_P278_R1.2061.00
26_V32_L1.1991.00
12_H57_A1.1931.00
259_E263_H1.1861.00
178_S201_L1.1821.00
108_S112_E1.1811.00
99_G151_R1.1801.00
24_L206_A1.1681.00
104_T151_R1.1631.00
32_L204_R1.1611.00
19_V22_I1.1561.00
252_R256_A1.1551.00
61_R64_G1.1451.00
12_H15_S1.1351.00
181_H186_T1.1221.00
94_E97_T1.1171.00
319_H328_Q1.1021.00
209_N230_F1.1001.00
307_T326_E1.0971.00
241_N245_V1.0911.00
255_V259_E1.0871.00
249_D252_R1.0861.00
117_D183_E1.0861.00
257_D260_G1.0841.00
258_H261_F1.0811.00
273_A277_R1.0791.00
28_D63_G1.0771.00
252_R255_V1.0711.00
321_T326_E1.0711.00
27_L204_R1.0651.00
46_L157_L1.0651.00
207_V231_V1.0651.00
207_V222_L1.0601.00
40_C208_L1.0591.00
55_A68_T1.0551.00
12_H18_A1.0531.00
116_A125_T1.0421.00
92_A135_L1.0411.00
9_L48_L1.0411.00
117_D121_T1.0381.00
70_S74_D1.0371.00
255_V258_H1.0331.00
101_Q108_S1.0241.00
118_A149_L1.0211.00
50_A157_L1.0211.00
220_Q311_P1.0181.00
204_R216_V1.0061.00
162_L190_Y1.0041.00
283_V288_V1.0011.00
29_E185_D0.9931.00
244_P280_T0.9931.00
298_H301_S0.9921.00
47_R52_L0.9901.00
96_M146_G0.9891.00
240_M282_G0.9881.00
213_V216_V0.9841.00
178_S182_R0.9831.00
319_H326_E0.9791.00
78_A148_A0.9791.00
24_L216_V0.9781.00
121_T183_E0.9781.00
273_A276_D0.9781.00
97_T101_Q0.9741.00
87_Y90_M0.9691.00
253_G256_A0.9661.00
31_F181_H0.9591.00
152_E183_E0.9521.00
93_A128_L0.9451.00
86_L132_P0.9421.00
98_F103_V0.9411.00
60_I67_V0.9381.00
244_P325_D0.9361.00
87_Y99_G0.9291.00
45_T208_L0.9281.00
131_T134_A0.9271.00
291_A294_S0.9241.00
106_Y114_R0.9221.00
254_L257_D0.9221.00
34_V206_A0.9161.00
35_V207_V0.9131.00
250_R253_G0.9121.00
224_D311_P0.9091.00
8_D57_A0.9041.00
311_P316_L0.8931.00
240_M243_V0.8921.00
304_A322_I0.8901.00
31_F201_L0.8881.00
264_P267_D0.8851.00
28_D154_S0.8841.00
71_P74_D0.8821.00
162_L177_L0.8801.00
95_N147_R0.8801.00
78_A153_P0.8781.00
62_I77_I0.8771.00
13_Y18_A0.8731.00
317_L328_Q0.8711.00
245_V279_L0.8691.00
108_S111_I0.8681.00
306_V318_L0.8661.00
78_A151_R0.8641.00
29_E187_T0.8561.00
9_L60_I0.8531.00
261_F264_P0.8521.00
5_T64_G0.8511.00
322_I325_D0.8421.00
130_R134_A0.8351.00
171_V175_A0.8331.00
192_T198_A0.8271.00
243_V247_V0.8251.00
30_E203_D0.8251.00
256_A260_G0.8121.00
33_V198_A0.8111.00
298_H306_V0.8091.00
96_M150_V0.8081.00
325_D329_V0.8071.00
6_L60_I0.8031.00
168_K233_G0.8001.00
48_L56_T0.7971.00
77_I155_V0.7971.00
240_M244_P0.7951.00
257_D261_F0.7921.00
96_M99_G0.7901.00
179_K308_V0.7791.00
31_F188_T0.7781.00
96_M119_A0.7741.00
26_V187_T0.7731.00
40_C45_T0.7701.00
153_P156_F0.7681.00
176_E179_K0.7641.00
37_P40_C0.7641.00
239_A242_L0.7601.00
325_D330_K0.7571.00
257_D262_A0.7561.00
325_D328_Q0.7521.00
34_V45_T0.7471.00
178_S200_T0.7451.00
175_A308_V0.7441.00
156_F188_T0.7431.00
21_G57_A0.7421.00
271_N275_V0.7391.00
119_A124_I0.7391.00
241_N244_P0.7391.00
76_D104_T0.7381.00
93_A111_I0.7371.00
152_E186_T0.7361.00
243_V327_L0.7351.00
43_S47_R0.7341.00
173_M176_E0.7341.00
196_T312_L0.7331.00
254_L258_H0.7321.00
320_C327_L0.7321.00
90_M94_E0.7291.00
156_F186_T0.7281.00
242_L245_V0.7271.00
13_Y53_E0.7251.00
223_Y226_P0.7221.00
91_T129_D0.7221.00
262_A265_L0.7201.00
22_I213_V0.7171.00
314_E330_K0.7171.00
167_A171_V0.7151.00
48_L53_E0.7141.00
306_V309_R0.7111.00
107_S111_I0.7101.00
223_Y286_E0.7041.00
7_T25_D0.7041.00
170_R194_D0.7011.00
286_E290_L0.7001.00
158_L190_Y0.6961.00
54_D69_D0.6951.00
196_T200_T0.6921.00
247_V250_R0.6921.00
248_R251_P0.6861.00
171_V196_T0.6841.00
269_G273_A0.6831.00
209_N212_T0.6811.00
160_E193_H0.6811.00
154_S186_T0.6761.00
118_A121_T0.6751.00
119_A125_T0.6741.00
208_L213_V0.6731.00
101_Q111_I0.6721.00
258_H262_A0.6721.00
257_D263_H0.6711.00
190_Y202_G0.6691.00
99_G147_R0.6661.00
262_A267_D0.6651.00
312_L317_L0.6631.00
167_A174_R0.6631.00
300_E303_E0.6621.00
262_A266_P0.6621.00
112_E115_V0.6571.00
175_A319_H0.6571.00
124_I127_L0.6521.00
245_V248_R0.6511.00
92_A143_V0.6491.00
90_M95_N0.6481.00
276_D279_L0.6471.00
84_Y164_N0.6471.00
283_V287_D0.6461.00
145_I158_L0.6461.00
126_E139_E0.6461.00
280_T284_R0.6451.00
308_V311_P0.6441.00
284_R287_D0.6441.00
215_Q231_V0.6431.00
32_L189_V0.6411.00
278_R282_G0.6391.00
248_R275_V0.6391.00
230_F234_F0.6371.00
270_S273_A0.6371.00
267_D270_S0.6371.00
78_A188_T0.6371.00
306_V320_C0.6331.00
34_V189_V0.6321.00
179_K307_T0.6321.00
238_P241_N0.6281.00
307_T319_H0.6271.00
30_E216_V0.6251.00
95_N132_P0.6241.00
309_R313_G0.6231.00
322_I327_L0.6221.00
321_T325_D0.6221.00
239_A243_V0.6221.00
132_P143_V0.6211.00
12_H20_D0.6201.00
31_F177_L0.6201.00
109_A112_E0.6191.00
177_L188_T0.6181.00
238_P242_L0.6181.00
272_S276_D0.6171.00
4_I26_V0.6151.00
172_H176_E0.6141.00
157_L189_V0.6131.00
123_G126_E0.6111.00
20_D210_D0.6111.00
288_V329_V0.6101.00
86_L95_N0.6101.00
302_F306_V0.6101.00
248_R253_G0.6101.00
243_V246_R0.6081.00
171_V237_E0.6071.00
263_H269_G0.6061.00
240_M245_V0.6061.00
191_V195_Q0.6051.00
258_H263_H0.6031.00
198_A202_G0.6031.00
6_L22_I0.5991.00
98_F101_Q0.5991.00
178_S203_D0.5971.00
164_N174_R0.5971.00
241_N246_R0.5961.00
14_D17_A0.5961.00
286_E330_K0.5941.00
290_L293_R0.5911.00
96_M118_A0.5911.00
118_A122_L0.5891.00
220_Q316_L0.5891.00
255_V262_A0.5881.00
59_T69_D0.5881.00
283_V286_E0.5871.00
50_A79_M0.5841.00
76_D151_R0.5821.00
163_S167_A0.5801.00
68_T72_P0.5771.00
20_D23_D0.5761.00
281_F284_R0.5751.00
253_G257_D0.5751.00
99_G104_T0.5751.00
34_V208_L0.5751.00
11_K19_V0.5731.00
256_A261_F0.5721.00
259_E265_L0.5701.00
180_L184_L0.5681.00
113_D120_A0.5681.00
282_G285_P0.5681.00
82_Q164_N0.5671.00
290_L294_S0.5661.00
27_L32_L0.5661.00
245_V252_R0.5651.00
304_A307_T0.5651.00
13_Y55_A0.5641.00
298_H305_R0.5631.00
87_Y95_N0.5631.00
195_Q234_F0.5621.00
126_E210_D0.5611.00
247_V279_L0.5611.00
145_I201_L0.5601.00
111_I114_R0.5581.00
119_A122_L0.5571.00
113_D116_A0.5551.00
272_S275_V0.5541.00
250_R255_V0.5531.00
245_V281_F0.5531.00
87_Y151_R0.5531.00
80_V148_A0.5521.00
181_H184_L0.5521.00
260_G266_P0.5521.00
24_L213_V0.5501.00
190_Y198_A0.5481.00
217_A222_L0.5451.00
114_R118_A0.5451.00
249_D253_G0.5431.00
285_P288_V0.5431.00
122_L173_M0.5431.00
106_Y109_A0.5421.00
125_T128_L0.5421.00
175_A179_K0.5421.00
306_V313_G0.5421.00
11_K44_T0.5411.00
249_D256_A0.5411.00
230_F233_G0.5401.00
149_L184_L0.5381.00
262_A269_G0.5381.00
17_A21_G0.5381.00
204_R215_Q0.5371.00
285_P289_L0.5361.00
26_V189_V0.5351.00
238_P244_P0.5351.00
170_R197_E0.5351.00
254_L262_A0.5341.00
308_V319_H0.5331.00
121_T179_K0.5331.00
256_A263_H0.5331.00
287_D290_L0.5331.00
248_R257_D0.5311.00
115_V118_A0.5301.00
281_F285_P0.5291.00
123_G176_E0.5281.00
241_N247_V0.5281.00
290_L329_V0.5281.00
304_A308_V0.5271.00
291_A300_E0.5271.00
252_R257_D0.5271.00
91_T132_P0.5261.00
67_V77_I0.5261.00
221_Q224_D0.5251.00
127_L139_E0.5241.00
274_L279_L0.5241.00
207_V226_P0.5231.00
305_R308_V0.5231.00
11_K18_A0.5221.00
93_A96_M0.5221.00
312_L315_Q0.5211.00
61_R68_T0.5211.00
284_R288_V0.5201.00
263_H267_D0.5191.00
219_P223_Y0.5191.00
83_N140_R0.5181.00
17_A57_A0.5181.00
300_E304_A0.5171.00
288_V327_L0.5151.00
286_E289_L0.5151.00
91_T95_N0.5151.00
288_V291_A0.5141.00
259_E264_P0.5141.00
259_E266_P0.5141.00
66_D70_S0.5131.00
316_L319_H0.5131.00
314_E317_L0.5121.00
177_L201_L0.5101.00
231_V234_F0.5101.00
80_V144_A0.5081.00
260_G264_P0.5071.00
276_D280_T0.5051.00
298_H313_G0.5020.99
251_P254_L0.5020.99
14_D18_A0.5020.99
299_E305_R0.5010.99
181_H203_D0.5000.99
301_S305_R0.5000.99
232_A236_G0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1v43A 2 0.9156 100 0.165 Contact Map
2it1A 1 0.9499 100 0.171 Contact Map
2yyzA 1 0.9393 100 0.178 Contact Map
1g291 4 0.9472 100 0.179 Contact Map
1oxxK 1 0.9024 100 0.185 Contact Map
3rlfA 2 0.9631 100 0.186 Contact Map
3fvqA 2 0.9103 100 0.205 Contact Map
4tquS 2 0.9525 100 0.212 Contact Map
3d31A 2 0.9024 100 0.215 Contact Map
1z47A 2 0.8971 100 0.219 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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