Q9HHN9 - HALSA - GREMLIN Contacts

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Q9HHN9 - Vng6302c

UniProt:	Q9HHN9	Sequences: MRWRHPSALRKADERGRRTPCVVSATSLAVGRIALALLLVVLNGFFVAAEFAFVRLRSASVETLVQDGRRGATAVKEATDNLDDYLAVSQLGITIASLGLGWVGEPAVAVLVDPLLEPVLPAPVRHTVTVALGFGIVTLLHVVYGELAPKTIAIQRAERVALVVAPVMKLFYYVFLPGTILFNGIATRSVQLIGVSPETEGHDTHTEPEILSVLSEASAAGRISPAEVSMIEHVFSLDDTTVREIMRPRPDVTSVSADTPLPELRTMAASGEYTRYPVTEGPDDDVIGFVDVKDILRASDAIDESGDVTARELSRPVVVVPETLRVDELLAEFQAEHRQMAVVIDEWGAFEGLATIEDALEVIVGDIRDQFDLATHAQSIEPRDDGGYEVPGAVSITELNDHLGTDFENEAVETVAGLVVSRLGHAPTVGDRAVIDTHTFRVTGVDGARITSLTVTPDS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	459 (413)
Sequences:	6889 (4693)
Seq/√Len:	230.9

ECOLI - YTFL YFJD YEGH YOAE CORC
BACSU - YUGS YHDP YQHB YHDT YRKA
HALSA - Q9HHN9 Q9HN02 Q9HRX1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
252_V	353_L	4.178	1.00
425_H	431_D	4.063	1.00
390_V	455_V	3.762	1.00
434_V	439_T	3.577	1.00
432_R	439_T	3.430	1.00
432_R	441_R	3.333	1.00
280_E	285_D	3.258	1.00
280_E	311_R	3.145	1.00
419_V	453_L	3.060	1.00
260_P	263_E	3.043	1.00
320_V	329_L	3.017	1.00
309_T	312_E	2.985	1.00
389_E	443_T	2.980	1.00
254_S	279_T	2.930	1.00
294_D	315_R	2.803	1.00
259_T	263_E	2.797	1.00
156_R	159_R	2.776	1.00
384_D	387_G	2.756	1.00
389_E	452_S	2.657	1.00
139_L	185_I	2.586	1.00
169_K	173_Y	2.563	1.00
439_T	456_T	2.503	1.00
342_V	353_L	2.438	1.00
257_A	280_E	2.393	1.00
278_V	314_S	2.378	1.00
180_I	184_G	2.355	1.00
252_V	350_F	2.349	1.00
242_V	329_L	2.343	1.00
324_L	332_E	2.333	1.00
399_L	403_L	2.322	1.00
441_R	456_T	2.313	1.00
418_L	435_I	2.300	1.00
61_V	75_V	2.165	1.00
342_V	350_F	2.147	1.00
74_A	169_K	2.137	1.00
415_V	453_L	2.090	1.00
443_T	454_T	2.083	1.00
45_F	167_V	2.073	1.00
383_R	387_G	2.057	1.00
444_G	452_S	2.040	1.00
254_S	283_D	2.020	1.00
399_L	455_V	2.013	1.00
387_G	454_T	2.008	1.00
257_A	311_R	1.983	1.00
69_R	162_L	1.970	1.00
380_I	394_V	1.913	1.00
245_I	326_V	1.907	1.00
394_V	399_L	1.901	1.00
255_V	264_L	1.900	1.00
84_D	176_L	1.890	1.00
329_L	354_A	1.885	1.00
266_T	270_S	1.871	1.00
446_D	451_T	1.854	1.00
74_A	166_P	1.853	1.00
257_A	287_I	1.849	1.00
77_E	169_K	1.822	1.00
163_V	167_V	1.819	1.00
214_L	231_I	1.796	1.00
43_N	97_S	1.793	1.00
289_F	317_V	1.790	1.00
64_L	162_L	1.772	1.00
60_S	158_E	1.754	1.00
65_V	76_K	1.736	1.00
188_R	192_L	1.733	1.00
255_V	278_V	1.732	1.00
340_M	353_L	1.729	1.00
387_G	456_T	1.713	1.00
444_G	451_T	1.712	1.00
394_V	415_V	1.679	1.00
258_D	280_E	1.673	1.00
279_T	286_V	1.664	1.00
382_P	388_Y	1.661	1.00
245_I	354_A	1.656	1.00
49_A	164_V	1.654	1.00
441_R	454_T	1.647	1.00
230_M	234_V	1.646	1.00
259_T	264_L	1.633	1.00
390_V	415_V	1.612	1.00
357_E	361_E	1.612	1.00
382_P	385_D	1.596	1.00
389_E	454_T	1.594	1.00
274_T	291_D	1.589	1.00
399_L	415_V	1.587	1.00
360_L	364_V	1.544	1.00
419_V	440_F	1.543	1.00
253_T	267_M	1.541	1.00
240_T	244_E	1.535	1.00
43_N	93_I	1.532	1.00
109_A	113_D	1.532	1.00
400_N	405_T	1.529	1.00
400_N	407_F	1.526	1.00
74_A	165_A	1.521	1.00
435_I	440_F	1.521	1.00
420_V	450_I	1.520	1.00
184_G	188_R	1.504	1.00
256_S	259_T	1.495	1.00
159_R	163_V	1.493	1.00
383_R	389_E	1.479	1.00
62_E	66_Q	1.478	1.00
383_R	454_T	1.463	1.00
71_G	162_L	1.452	1.00
230_M	363_I	1.452	1.00
284_D	349_A	1.445	1.00
419_V	442_V	1.441	1.00
331_A	334_Q	1.440	1.00
75_V	165_A	1.439	1.00
326_V	359_A	1.434	1.00
280_E	287_I	1.432	1.00
440_F	453_L	1.428	1.00
383_R	386_G	1.427	1.00
68_G	72_A	1.422	1.00
148_A	189_S	1.419	1.00
34_A	38_L	1.414	1.00
253_T	273_Y	1.414	1.00
422_R	435_I	1.402	1.00
322_E	351_E	1.398	1.00
390_V	399_L	1.388	1.00
289_F	340_M	1.386	1.00
419_V	433_A	1.383	1.00
249_R	284_D	1.379	1.00
263_E	266_T	1.374	1.00
73_T	77_E	1.371	1.00
48_A	160_V	1.368	1.00
282_P	285_D	1.368	1.00
324_L	329_L	1.361	1.00
33_I	37_L	1.355	1.00
88_V	171_F	1.352	1.00
412_V	421_S	1.346	1.00
45_F	164_V	1.342	1.00
234_V	363_I	1.306	1.00
275_R	339_Q	1.303	1.00
164_V	167_V	1.298	1.00
443_T	452_S	1.291	1.00
31_G	35_L	1.290	1.00
113_D	117_E	1.278	1.00
76_K	80_D	1.275	1.00
62_E	76_K	1.271	1.00
71_G	166_P	1.263	1.00
127_T	131_A	1.261	1.00
88_V	179_T	1.256	1.00
419_V	423_L	1.256	1.00
69_R	72_A	1.244	1.00
380_I	402_H	1.243	1.00
396_I	400_N	1.229	1.00
166_P	170_L	1.226	1.00
250_P	349_A	1.225	1.00
173_Y	176_L	1.224	1.00
438_H	455_V	1.218	1.00
167_V	170_L	1.218	1.00
75_V	161_A	1.216	1.00
369_D	372_D	1.212	1.00
46_F	92_G	1.207	1.00
104_G	137_V	1.205	1.00
259_T	267_M	1.197	1.00
152_I	195_V	1.190	1.00
253_T	271_G	1.190	1.00
64_L	69_R	1.182	1.00
131_A	135_G	1.176	1.00
35_L	103_V	1.162	1.00
51_F	54_V	1.159	1.00
256_S	281_G	1.156	1.00
184_G	187_T	1.147	1.00
298_A	313_L	1.141	1.00
381_E	389_E	1.140	1.00
38_L	42_L	1.139	1.00
46_F	171_F	1.139	1.00
65_V	73_T	1.124	1.00
317_V	342_V	1.121	1.00
253_T	276_Y	1.116	1.00
286_V	342_V	1.111	1.00
321_P	324_L	1.109	1.00
70_R	73_T	1.104	1.00
275_R	357_E	1.099	1.00
403_L	438_H	1.094	1.00
379_S	391_P	1.089	1.00
332_E	336_E	1.088	1.00
416_A	420_V	1.083	1.00
145_G	150_K	1.082	1.00
284_D	350_F	1.079	1.00
176_L	180_I	1.076	1.00
357_E	372_D	1.075	1.00
340_M	355_T	1.072	1.00
90_Q	93_I	1.067	1.00
290_V	313_L	1.063	1.00
190_V	195_V	1.063	1.00
249_R	349_A	1.061	1.00
61_V	76_K	1.060	1.00
251_D	449_R	1.052	1.00
98_L	101_G	1.044	1.00
357_E	367_I	1.031	1.00
420_V	426_A	1.031	1.00
287_I	314_S	1.029	1.00
433_A	440_F	1.029	1.00
255_V	310_A	1.027	1.00
242_V	320_V	1.026	1.00
271_G	276_Y	1.020	1.00
311_R	314_S	1.018	1.00
254_S	350_F	1.017	1.00
97_S	141_H	1.014	1.00
245_I	359_A	1.012	1.00
50_E	150_K	1.005	1.00
56_L	61_V	0.997	1.00
265_R	269_A	0.994	1.00
333_F	341_A	0.988	1.00
380_I	390_V	0.985	1.00
242_V	343_V	0.980	1.00
78_A	85_Y	0.980	1.00
257_A	314_S	0.978	1.00
43_N	47_V	0.977	1.00
391_P	452_S	0.977	1.00
281_G	285_D	0.969	1.00
47_V	51_F	0.967	1.00
40_V	145_G	0.951	1.00
268_A	276_Y	0.944	1.00
218_S	228_V	0.944	1.00
65_V	68_G	0.942	1.00
324_L	328_E	0.940	1.00
392_G	415_V	0.939	1.00
422_R	433_A	0.934	1.00
217_A	221_G	0.933	1.00
308_V	312_E	0.932	1.00
256_S	279_T	0.932	1.00
49_A	168_M	0.928	1.00
42_L	96_A	0.928	1.00
61_V	79_T	0.925	1.00
320_V	341_A	0.924	1.00
56_L	157_A	0.924	1.00
434_V	437_T	0.922	1.00
380_I	388_Y	0.918	1.00
170_L	173_Y	0.915	1.00
266_T	300_D	0.914	1.00
429_V	444_G	0.914	1.00
418_L	440_F	0.913	1.00
48_A	153_A	0.910	1.00
72_A	162_L	0.910	1.00
112_V	115_L	0.908	1.00
63_T	67_D	0.908	1.00
101_G	104_G	0.900	0.99
266_T	269_A	0.899	0.99
135_G	139_L	0.898	0.99
146_E	150_K	0.895	0.99
367_I	372_D	0.889	0.99
357_E	370_Q	0.886	0.99
108_V	111_L	0.885	0.99
36_A	137_V	0.880	0.99
172_Y	176_L	0.880	0.99
181_L	184_G	0.879	0.99
395_S	398_E	0.878	0.99
98_L	105_E	0.878	0.99
71_G	75_V	0.877	0.99
258_D	311_R	0.875	0.99
31_G	34_A	0.873	0.99
277_P	289_F	0.872	0.99
210_I	217_A	0.871	0.99
423_L	427_P	0.871	0.99
440_F	455_V	0.868	0.99
78_A	165_A	0.868	0.99
81_N	84_D	0.868	0.99
345_D	351_E	0.864	0.99
423_L	433_A	0.862	0.99
291_D	294_D	0.858	0.99
93_I	97_S	0.858	0.99
262_P	266_T	0.857	0.99
242_V	354_A	0.856	0.99
205_H	213_V	0.856	0.99
94_T	138_T	0.854	0.99
207_E	239_D	0.854	0.99
308_V	313_L	0.850	0.99
400_N	406_D	0.848	0.99
268_A	295_I	0.847	0.99
163_V	166_P	0.847	0.99
294_D	371_F	0.842	0.99
112_V	116_L	0.841	0.99
382_P	386_G	0.840	0.99
339_Q	360_L	0.839	0.99
102_W	134_F	0.830	0.99
320_V	343_V	0.830	0.99
210_I	223_I	0.829	0.99
416_A	449_R	0.829	0.99
252_V	283_D	0.828	0.99
251_D	393_A	0.827	0.99
74_A	77_E	0.823	0.99
318_V	332_E	0.820	0.99
346_E	417_G	0.816	0.99
418_L	422_R	0.815	0.99
392_G	416_A	0.813	0.99
318_V	341_A	0.811	0.99
106_P	109_A	0.806	0.99
88_V	172_Y	0.805	0.99
261_L	264_L	0.804	0.99
43_N	141_H	0.803	0.99
380_I	399_L	0.803	0.99
361_E	366_D	0.802	0.99
207_E	235_F	0.802	0.99
105_E	110_V	0.800	0.99
196_S	199_T	0.800	0.99
188_R	191_Q	0.799	0.99
129_T	133_G	0.797	0.99
187_T	191_Q	0.796	0.99
287_I	311_R	0.793	0.99
191_Q	196_S	0.793	0.99
255_V	267_M	0.792	0.99
255_V	276_Y	0.785	0.99
93_I	146_E	0.785	0.99
65_V	69_R	0.784	0.99
93_I	147_L	0.784	0.99
98_L	138_T	0.784	0.99
115_L	118_P	0.783	0.99
166_P	169_K	0.783	0.99
105_E	109_A	0.782	0.99
257_A	264_L	0.782	0.99
64_L	72_A	0.781	0.99
45_F	92_G	0.780	0.99
111_L	114_P	0.780	0.99
412_V	418_L	0.779	0.98
110_V	114_P	0.777	0.98
261_L	308_V	0.776	0.98
48_A	52_A	0.775	0.98
177_P	181_L	0.770	0.98
275_R	370_Q	0.769	0.98
243_R	322_E	0.767	0.98
52_A	161_A	0.763	0.98
422_R	436_D	0.759	0.98
243_R	351_E	0.759	0.98
339_Q	357_E	0.758	0.98
58_S	80_D	0.757	0.98
94_T	150_K	0.757	0.98
274_T	293_K	0.757	0.98
51_F	153_A	0.755	0.98
77_E	81_N	0.755	0.98
264_L	309_T	0.752	0.98
125_R	129_T	0.752	0.98
44_G	48_A	0.751	0.98
93_I	96_A	0.751	0.98
356_I	367_I	0.750	0.98
277_P	342_V	0.750	0.98
237_L	359_A	0.748	0.98
101_G	105_E	0.748	0.98
161_A	165_A	0.745	0.98
269_A	297_R	0.744	0.98
237_L	327_D	0.744	0.98
60_S	64_L	0.743	0.98
93_I	141_H	0.743	0.98
345_D	348_G	0.740	0.98
83_D	151_T	0.737	0.98
279_T	282_P	0.737	0.98
100_L	137_V	0.736	0.98
275_R	291_D	0.734	0.98
332_E	335_A	0.733	0.98
128_V	132_L	0.733	0.98
304_E	307_D	0.733	0.98
35_L	38_L	0.731	0.98
160_V	164_V	0.730	0.98
196_S	200_E	0.728	0.98
41_V	44_G	0.727	0.98
396_I	412_V	0.726	0.98
231_I	235_F	0.725	0.98
90_Q	94_T	0.724	0.98
264_L	310_A	0.723	0.98
101_G	138_T	0.723	0.98
249_R	345_D	0.723	0.98
391_P	394_V	0.721	0.98
237_L	330_L	0.721	0.98
71_G	163_V	0.720	0.97
368_R	374_A	0.720	0.97
82_L	85_Y	0.720	0.97
155_Q	195_V	0.719	0.97
330_L	359_A	0.719	0.97
56_L	75_V	0.719	0.97
40_V	43_N	0.716	0.97
268_A	292_V	0.715	0.97
214_L	218_S	0.714	0.97
392_G	450_I	0.713	0.97
257_A	260_P	0.712	0.97
321_P	346_E	0.711	0.97
110_V	113_D	0.709	0.97
147_L	182_F	0.706	0.97
98_L	134_F	0.704	0.97
78_A	172_Y	0.701	0.97
100_L	141_H	0.700	0.97
423_L	431_D	0.700	0.97
361_E	372_D	0.698	0.97
306_G	309_T	0.698	0.97
357_E	366_D	0.696	0.97
362_V	366_D	0.693	0.97
113_D	129_T	0.692	0.97
94_T	141_H	0.691	0.97
406_D	436_D	0.689	0.97
47_V	146_E	0.688	0.97
383_R	444_G	0.687	0.97
35_L	39_L	0.687	0.97
426_A	445_V	0.687	0.97
36_A	100_L	0.685	0.97
40_V	140_L	0.682	0.97
211_L	232_E	0.681	0.96
305_S	308_V	0.680	0.96
47_V	141_H	0.679	0.96
277_P	286_V	0.675	0.96
330_L	364_V	0.671	0.96
310_A	314_S	0.670	0.96
60_S	63_T	0.669	0.96
81_N	172_Y	0.667	0.96
357_E	362_V	0.667	0.96
101_G	106_P	0.664	0.96
43_N	94_T	0.663	0.96
96_A	138_T	0.662	0.96
242_V	324_L	0.661	0.96
107_A	110_V	0.661	0.96
411_A	421_S	0.655	0.96
43_N	96_A	0.652	0.96
71_G	165_A	0.651	0.95
361_E	369_D	0.650	0.95
47_V	93_I	0.649	0.95
113_D	118_P	0.648	0.95
89_S	168_M	0.648	0.95
429_V	445_V	0.647	0.95
103_V	106_P	0.647	0.95
105_E	142_V	0.646	0.95
286_V	350_F	0.646	0.95
99_G	130_V	0.645	0.95
381_E	452_S	0.644	0.95
450_I	453_L	0.644	0.95
382_P	387_G	0.644	0.95
405_T	438_H	0.643	0.95
170_L	174_V	0.643	0.95
357_E	369_D	0.642	0.95
318_V	336_E	0.641	0.95
317_V	340_M	0.641	0.95
291_D	315_R	0.640	0.95
286_V	319_V	0.639	0.95
241_T	244_E	0.637	0.95
329_L	359_A	0.637	0.95
71_G	74_A	0.637	0.95
279_T	283_D	0.636	0.95
345_D	349_A	0.635	0.95
182_F	186_A	0.635	0.95
275_R	340_M	0.635	0.95
109_A	129_T	0.635	0.95
49_A	53_F	0.632	0.95
86_L	145_G	0.632	0.95
178_G	182_F	0.631	0.95
267_M	270_S	0.630	0.95
47_V	94_T	0.629	0.95
407_F	418_L	0.628	0.95
400_N	410_E	0.625	0.94
230_M	237_L	0.624	0.94
43_N	90_Q	0.621	0.94
69_R	73_T	0.620	0.94
114_P	117_E	0.619	0.94
64_L	67_D	0.617	0.94
83_D	187_T	0.616	0.94
90_Q	147_L	0.616	0.94
207_E	211_L	0.614	0.94
304_E	308_V	0.614	0.94
83_D	87_A	0.612	0.94
244_E	413_E	0.611	0.94
144_Y	189_S	0.609	0.94
377_A	381_E	0.608	0.94
47_V	97_S	0.607	0.93
86_L	90_Q	0.606	0.93
228_V	232_E	0.606	0.93
138_T	142_V	0.604	0.93
403_L	455_V	0.602	0.93
101_G	134_F	0.602	0.93
75_V	162_L	0.601	0.93
277_P	413_E	0.598	0.93
85_Y	91_L	0.597	0.93
357_E	371_F	0.597	0.93
274_T	370_Q	0.596	0.93
106_P	110_V	0.595	0.93
91_L	178_G	0.594	0.93
102_W	105_E	0.594	0.93
318_V	338_R	0.594	0.93
50_E	146_E	0.592	0.93
364_V	367_I	0.591	0.93
428_T	431_D	0.591	0.93
75_V	79_T	0.590	0.92
61_V	72_A	0.588	0.92
402_H	405_T	0.587	0.92
84_D	172_Y	0.587	0.92
229_S	233_H	0.587	0.92
96_A	134_F	0.587	0.92
59_A	212_S	0.586	0.92
93_I	145_G	0.585	0.92
399_L	402_H	0.584	0.92
211_L	236_S	0.583	0.92
312_E	316_P	0.582	0.92
73_T	76_K	0.581	0.92
56_L	158_E	0.580	0.92
339_Q	367_I	0.580	0.92
190_V	194_G	0.580	0.92
99_G	103_V	0.580	0.92
388_Y	402_H	0.579	0.92
94_T	134_F	0.578	0.92
278_V	310_A	0.578	0.92
268_A	296_L	0.577	0.92
416_A	450_I	0.576	0.92
243_R	413_E	0.576	0.92
329_L	333_F	0.576	0.92
328_E	331_A	0.575	0.92
40_V	100_L	0.574	0.91
159_R	162_L	0.573	0.91
42_L	46_F	0.573	0.91
247_R	368_R	0.573	0.91
183_N	186_A	0.572	0.91
275_R	289_F	0.571	0.91
420_V	431_D	0.571	0.91
379_S	394_V	0.570	0.91
151_T	154_I	0.570	0.91
315_R	338_R	0.569	0.91
114_P	118_P	0.569	0.91
134_F	141_H	0.567	0.91
233_H	363_I	0.566	0.91
32_R	36_A	0.566	0.91
90_Q	97_S	0.564	0.91
445_V	448_A	0.563	0.91
356_I	364_V	0.563	0.91
55_R	85_Y	0.562	0.91
330_L	356_I	0.561	0.91
157_A	160_V	0.561	0.91
264_L	268_A	0.561	0.91
361_E	367_I	0.560	0.90
50_E	94_T	0.559	0.90
263_E	267_M	0.557	0.90
96_A	145_G	0.556	0.90
171_F	175_F	0.554	0.90
396_I	407_F	0.554	0.90
103_V	107_A	0.553	0.90
331_A	335_A	0.552	0.90
89_S	96_A	0.552	0.90
130_V	134_F	0.551	0.90
249_R	346_E	0.551	0.90
54_V	87_A	0.550	0.90
300_D	308_V	0.548	0.89
298_A	308_V	0.548	0.89
112_V	129_T	0.547	0.89
58_S	76_K	0.546	0.89
77_E	173_Y	0.546	0.89
284_D	346_E	0.546	0.89
134_F	137_V	0.545	0.89
132_L	136_I	0.545	0.89
101_G	142_V	0.544	0.89
360_L	367_I	0.543	0.89
242_V	246_M	0.542	0.89
65_V	71_G	0.542	0.89
283_D	350_F	0.542	0.89
90_Q	141_H	0.542	0.89
39_L	96_A	0.540	0.89
56_L	85_Y	0.539	0.89
439_T	443_T	0.539	0.89
109_A	114_P	0.537	0.89
51_F	90_Q	0.537	0.89
299_S	305_S	0.536	0.88
90_Q	101_G	0.535	0.88
253_T	270_S	0.535	0.88
270_S	373_L	0.535	0.88
256_S	280_E	0.533	0.88
138_T	150_K	0.532	0.88
396_I	399_L	0.532	0.88
249_R	347_W	0.532	0.88
72_A	161_A	0.532	0.88
174_V	177_P	0.530	0.88
44_G	145_G	0.530	0.88
109_A	112_V	0.530	0.88
386_G	456_T	0.529	0.88
451_T	454_T	0.529	0.88
212_S	216_E	0.529	0.88
207_E	238_D	0.528	0.88
107_A	133_G	0.528	0.88
152_I	160_V	0.528	0.88
177_P	180_I	0.527	0.88
391_P	451_T	0.527	0.88
275_R	369_D	0.526	0.88
408_E	412_V	0.526	0.88
113_D	116_L	0.526	0.88
261_L	265_R	0.526	0.88
214_L	223_I	0.525	0.87
47_V	89_S	0.525	0.87
418_L	433_A	0.525	0.87
85_Y	168_M	0.524	0.87
36_A	107_A	0.524	0.87
320_V	324_L	0.522	0.87
254_S	286_V	0.522	0.87
56_L	162_L	0.522	0.87
319_V	344_I	0.522	0.87
388_Y	403_L	0.521	0.87
98_L	133_G	0.521	0.87
91_L	94_T	0.521	0.87
43_N	138_T	0.521	0.87
97_S	134_F	0.520	0.87
90_Q	151_T	0.520	0.87
53_F	161_A	0.520	0.87
98_L	106_P	0.518	0.87
55_R	154_I	0.518	0.87
113_D	126_H	0.518	0.87
324_L	343_V	0.517	0.87
357_E	364_V	0.517	0.87
394_V	398_E	0.516	0.87
86_L	150_K	0.516	0.87
87_A	94_T	0.516	0.87
97_S	101_G	0.516	0.87
390_V	402_H	0.514	0.86
244_E	420_V	0.513	0.86
88_V	91_L	0.512	0.86
305_S	310_A	0.511	0.86
97_S	102_W	0.511	0.86
217_A	222_R	0.511	0.86
361_E	370_Q	0.510	0.86
91_L	138_T	0.510	0.86
116_L	128_V	0.508	0.86
89_S	134_F	0.507	0.86
255_V	259_T	0.507	0.86
51_F	91_L	0.505	0.85
152_I	156_R	0.504	0.85
235_F	238_D	0.504	0.85
77_E	80_D	0.504	0.85
279_T	287_I	0.503	0.85
215_S	232_E	0.502	0.85
418_L	436_D	0.501	0.85
108_V	112_V	0.500	0.85

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4hg0A	2	0.5054	100	0.536	Contact Map
3lhhA	1	0.2723	100	0.781	Contact Map
3ocoA	2	0.2941	99.9	0.798	Contact Map
3oi8A	2	0.3399	99.9	0.798	Contact Map
3ocmA	5	0.3246	99.9	0.803	Contact Map
2v8qE	1	0.4989	99.9	0.803	Contact Map
3kxrA	3	0.3508	99.9	0.806	Contact Map
3lv9A	2	0.2832	99.9	0.812	Contact Map
4iysA	2	0.3094	99.9	0.818	Contact Map
3dedA	2	0.1874	99.9	0.82	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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