GREMLIN Database
SYR - Arginine--tRNA ligase
UniProt: Q9HHN2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 631 (558)
Sequences: 2654 (1753)
Seq/√Len: 74.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
124_T162_D5.9231.00
579_L619_G5.6811.00
302_E306_E4.6351.00
185_E241_S4.0041.00
65_A69_D3.9941.00
277_D479_T3.9941.00
277_D453_D3.8501.00
155_I622_L3.7691.00
248_R253_D3.7461.00
58_A66_A3.5371.00
460_E475_Q3.4581.00
305_I317_S3.3891.00
59_P62_D3.3341.00
303_K307_N3.2371.00
434_P502_D3.0621.00
247_T251_Q3.0461.00
82_A93_H2.9541.00
452_L486_I2.9521.00
244_E248_R2.9111.00
398_V406_F2.8841.00
157_E165_R2.8581.00
68_A90_I2.8241.00
272_K276_D2.7671.00
464_A474_A2.7071.00
524_G609_T2.6951.00
521_A627_V2.5951.00
145_N428_Y2.5711.00
411_V414_R2.5611.00
594_A597_D2.5551.00
153_M165_R2.5151.00
184_T255_D2.5031.00
382_I413_A2.4741.00
106_T110_D2.3841.00
302_E305_I2.3611.00
107_I556_L2.3551.00
559_Y618_N2.3061.00
96_T550_V2.2581.00
151_A154_N2.2571.00
206_Q210_R2.2491.00
476_S480_K2.2371.00
279_D626_D2.2291.00
254_E258_A2.2281.00
206_Q209_Q2.2151.00
460_E464_A2.2001.00
595_V609_T2.1951.00
555_E585_V2.1921.00
245_W256_A2.1801.00
240_D244_E2.1681.00
61_V87_G2.1651.00
488_Y512_D2.1561.00
159_R567_E2.1511.00
521_A525_Y2.1441.00
123_D392_D2.1261.00
410_F423_L2.1231.00
458_R461_E2.1141.00
480_K626_D2.1091.00
123_D393_Q2.0901.00
424_K570_Y2.0681.00
477_V481_I2.0511.00
299_V387_E2.0141.00
521_A617_D2.0131.00
81_E95_D1.9721.00
298_D302_E1.9691.00
503_I507_V1.9661.00
479_T626_D1.9221.00
393_Q424_K1.9181.00
261_E265_T1.9061.00
305_I366_V1.8481.00
578_Y582_L1.8401.00
473_E476_S1.8371.00
525_Y613_T1.8351.00
124_T164_T1.8341.00
127_A152_V1.8321.00
563_L622_L1.8321.00
521_A613_T1.8161.00
130_S275_Y1.8051.00
566_C575_L1.7991.00
454_R458_R1.7941.00
458_R504_D1.7851.00
586_F609_T1.7821.00
529_D629_E1.7651.00
363_F375_G1.7621.00
476_S479_T1.7251.00
254_E261_E1.7211.00
113_E116_T1.7161.00
130_S146_T1.7061.00
456_Q479_T1.7041.00
150_D154_N1.7011.00
158_A618_N1.6991.00
555_E558_R1.6931.00
66_A69_D1.6881.00
484_A518_Q1.6831.00
401_E430_L1.6701.00
614_Q618_N1.6441.00
384_Y388_E1.6441.00
550_V554_F1.6401.00
303_K418_Y1.6301.00
618_N621_G1.6000.99
277_D456_Q1.5920.99
265_T269_D1.5670.99
185_E210_R1.5640.99
44_F94_A1.5600.99
525_Y629_E1.5580.99
33_L44_F1.5560.99
432_S498_D1.5380.99
96_T547_D1.5340.99
125_I161_H1.5150.99
312_R317_S1.5110.99
610_K614_Q1.5100.99
520_A587_N1.4870.99
546_N549_D1.4860.99
16_A20_A1.4820.99
13_I16_A1.4790.99
67_I90_I1.4730.99
284_V389_Y1.4680.99
395_V426_I1.4670.99
373_L376_T1.4660.99
310_A317_S1.4640.99
62_D66_A1.4570.99
156_L570_Y1.4520.99
186_F210_R1.4510.99
299_V302_E1.4440.99
156_L567_E1.4380.99
158_A559_Y1.4370.99
15_A19_D1.4240.99
558_R561_L1.4220.99
556_L615_I1.4220.99
456_Q475_Q1.4210.99
152_V426_I1.4180.99
300_I383_E1.4160.99
579_L616_F1.4150.99
188_D191_T1.4140.99
274_T449_R1.4130.99
596_L602_R1.4120.99
37_T41_K1.4040.99
457_D461_E1.4020.99
531_A606_L1.3990.99
527_I595_V1.3970.99
159_R563_L1.3920.98
303_K306_E1.3850.98
257_T261_E1.3850.98
81_E96_T1.3770.98
453_D457_D1.3770.98
524_G586_F1.3730.98
61_V65_A1.3710.98
515_P631_M1.3670.98
267_S271_F1.3640.98
542_P545_F1.3480.98
552_L612_T1.3420.98
189_E193_E1.3380.98
244_E247_T1.3310.98
84_T93_H1.3280.98
470_D473_E1.3260.98
101_D105_S1.3260.98
565_R569_R1.3240.98
488_Y580_L1.3230.98
299_V303_K1.3230.98
253_D256_A1.3210.98
582_L612_T1.3180.98
304_A416_M1.3160.98
207_F238_H1.3130.98
277_D452_L1.3100.98
129_V165_R1.3030.98
155_I566_C1.3010.98
363_F409_L1.3010.98
575_L619_G1.3000.98
363_F412_A1.3000.98
580_L584_H1.2930.98
122_P161_H1.2930.98
303_K383_E1.2920.98
181_H242_G1.2890.97
383_E387_E1.2850.97
364_Y375_G1.2850.97
68_A85_V1.2840.97
480_K628_L1.2730.97
317_S366_V1.2700.97
411_V415_K1.2700.97
549_D605_R1.2680.97
58_A62_D1.2640.97
472_A630_E1.2580.97
166_D381_T1.2550.97
150_D487_K1.2510.97
319_Y412_A1.2510.97
12_G15_A1.2490.97
154_N621_G1.2470.97
485_T515_P1.2440.97
61_V85_V1.2420.97
75_G95_D1.2370.97
456_Q483_L1.2360.97
195_D198_E1.2300.97
290_F384_Y1.2300.97
399_A403_N1.2230.97
456_Q460_E1.2190.96
382_I396_Y1.2150.96
127_A163_V1.2150.96
181_H245_W1.2100.96
129_V153_M1.2000.96
395_V570_Y1.1970.96
126_L391_A1.1960.96
199_H203_L1.1920.96
358_A415_K1.1920.96
400_N427_D1.1880.96
301_I365_I1.1860.96
462_I465_E1.1840.96
22_Y25_E1.1840.96
155_I567_E1.1760.96
471_D475_Q1.1630.95
375_G412_A1.1620.95
597_D602_R1.1610.95
199_H202_D1.1600.95
43_E554_F1.1590.95
301_I305_I1.1590.95
198_E201_L1.1580.95
202_D206_Q1.1570.95
140_V451_V1.1530.95
509_L515_P1.1520.95
556_L582_L1.1510.95
150_D624_G1.1460.95
56_A63_V1.1460.95
620_L625_I1.1450.95
598_A601_A1.1420.95
107_I611_A1.1390.95
58_A63_V1.1380.95
546_N593_N1.1340.95
401_E437_S1.1300.95
589_F593_N1.1260.94
555_E581_Q1.1220.94
201_L445_I1.1190.94
127_A153_M1.1120.94
399_A430_L1.1060.94
83_V92_Y1.1040.94
305_I310_A1.1000.94
492_A505_E1.0950.94
593_N605_R1.0920.94
154_N157_E1.0910.94
266_V269_D1.0880.93
11_A15_A1.0830.93
182_E185_E1.0810.93
237_Y240_D1.0780.93
397_V426_I1.0770.93
481_I515_P1.0750.93
547_D551_E1.0740.93
379_L413_A1.0730.93
460_E478_A1.0720.93
12_G16_A1.0690.93
240_D243_K1.0650.93
461_E464_A1.0590.92
375_G409_L1.0580.92
16_A19_D1.0550.92
38_D41_K1.0550.92
107_I615_I1.0550.92
18_S25_E1.0540.92
456_Q482_A1.0530.92
519_Y587_N1.0510.92
305_I312_R1.0510.92
182_E203_L1.0490.92
43_E550_V1.0470.92
311_M320_I1.0470.92
361_D404_Q1.0470.92
139_H431_I1.0450.92
303_K416_M1.0450.92
455_A458_R1.0360.92
300_I380_A1.0350.92
130_S167_N1.0320.91
610_K613_T1.0320.91
104_L108_L1.0310.91
178_N207_F1.0290.91
126_L394_S1.0240.91
143_L490_M1.0240.91
454_R503_I1.0120.91
594_A598_A1.0110.91
385_R396_Y1.0090.91
461_E465_E1.0050.90
157_E281_A1.0030.90
85_V88_G1.0020.90
620_L627_V1.0020.90
73_S80_V1.0000.90
521_A629_E1.0000.90
404_Q408_Q0.9970.90
586_F590_Y0.9970.90
152_V397_V0.9950.90
395_V424_K0.9930.90
385_R394_S0.9920.90
52_I63_V0.9900.90
393_Q422_K0.9900.90
10_L14_R0.9890.90
94_A99_L0.9890.90
313_G316_E0.9860.90
463_I467_G0.9840.89
61_V86_E0.9830.89
391_A394_S0.9780.89
168_H291_Y0.9780.89
313_G318_V0.9770.89
276_D281_A0.9770.89
548_T592_K0.9760.89
116_T158_A0.9730.89
157_E163_V0.9720.89
564_E568_E0.9680.89
555_E582_L0.9680.89
559_Y619_G0.9640.88
182_E207_F0.9640.88
471_D474_A0.9620.88
313_G362_P0.9620.88
476_S626_D0.9610.88
270_R273_Q0.9590.88
108_L607_L0.9540.88
303_K387_E0.9500.88
71_H83_V0.9470.88
398_V427_D0.9440.87
210_R235_R0.9410.87
16_A22_Y0.9390.87
613_T617_D0.9390.87
14_R18_S0.9360.87
144_R490_M0.9340.87
403_N407_Q0.9310.87
36_I45_S0.9300.87
312_R315_G0.9290.87
10_L13_I0.9290.87
35_D558_R0.9200.86
272_K285_W0.9140.86
559_Y563_L0.9130.86
461_E504_D0.9120.85
527_I609_T0.9110.85
559_Y615_I0.9100.85
300_I379_L0.9070.85
478_A482_A0.9060.85
426_I570_Y0.9050.85
480_K484_A0.9050.85
552_L582_L0.9050.85
403_N427_D0.9030.85
364_Y373_L0.9020.85
529_D630_E0.9010.85
541_D604_E0.9000.85
13_I25_E0.8990.85
617_D629_E0.8990.85
526_S529_D0.8970.85
611_A614_Q0.8960.84
189_E262_R0.8950.84
369_D373_L0.8930.84
19_D70_A0.8870.84
72_R82_A0.8840.84
210_R238_H0.8810.83
80_V92_Y0.8760.83
522_T525_Y0.8760.83
64_A85_V0.8730.83
454_R457_D0.8730.83
113_E158_A0.8730.83
181_H185_E0.8720.83
357_D415_K0.8710.83
39_E42_G0.8700.83
549_D593_N0.8690.83
463_I466_K0.8690.83
118_T121_D0.8680.83
541_D545_F0.8660.82
297_N377_R0.8650.82
209_Q219_D0.8640.82
396_Y410_F0.8610.82
66_A70_A0.8600.82
372_T377_R0.8600.82
143_L147_I0.8560.82
521_A628_L0.8560.82
427_D496_E0.8520.81
291_Y384_Y0.8420.81
132_P260_W0.8410.81
398_V425_H0.8410.81
245_W248_R0.8390.80
286_N289_S0.8390.80
291_Y381_T0.8390.80
15_A18_S0.8390.80
62_D65_A0.8360.80
252_G257_T0.8360.80
525_Y529_D0.8350.80
191_T194_D0.8330.80
251_Q371_S0.8320.80
80_V83_V0.8310.80
49_S67_I0.8310.80
396_Y405_Y0.8290.80
562_V565_R0.8290.80
136_K402_Q0.8280.79
119_D564_E0.8280.79
13_I22_Y0.8280.79
161_H393_Q0.8260.79
13_I67_I0.8240.79
250_E377_R0.8230.79
125_I156_L0.8230.79
132_P167_N0.8200.79
533_A602_R0.8200.79
41_K45_S0.8160.78
210_R219_D0.8160.78
544_V601_A0.8120.78
462_I466_K0.8110.78
382_I420_D0.8100.78
175_Q440_T0.8100.78
468_R471_D0.8090.78
381_T385_R0.8090.78
386_I390_D0.8070.78
268_I284_V0.8070.78
548_T588_S0.8070.78
524_G613_T0.8070.78
114_Y614_Q0.8010.77
473_E630_E0.7940.77
166_D284_V0.7930.76
147_I280_V0.7900.76
383_E418_Y0.7900.76
386_I394_S0.7900.76
519_Y590_Y0.7880.76
358_A411_V0.7880.76
536_E539_D0.7870.76
95_D98_D0.7870.76
49_S63_V0.7860.76
301_I304_A0.7850.76
432_S500_T0.7850.76
172_W292_A0.7840.76
455_A486_I0.7830.76
183_Y263_F0.7830.76
153_M157_E0.7760.75
384_Y389_Y0.7760.75
46_S49_S0.7750.75
174_V367_K0.7740.75
147_I278_L0.7720.75
178_N208_E0.7720.75
105_S109_R0.7700.74
236_D239_A0.7680.74
117_R159_R0.7670.74
482_A486_I0.7630.74
182_E186_F0.7600.73
556_L612_T0.7590.73
147_I490_M0.7580.73
439_S442_K0.7570.73
143_L172_W0.7570.73
14_R25_E0.7550.73
145_N490_M0.7550.73
597_D600_N0.7550.73
208_E218_E0.7540.73
313_G375_G0.7520.73
132_P275_Y0.7520.73
148_L428_Y0.7520.73
123_D161_H0.7520.73
474_A477_V0.7510.73
47_P50_F0.7480.72
126_L166_D0.7470.72
135_A490_M0.7470.72
127_A397_V0.7460.72
181_H238_H0.7440.72
108_L610_K0.7440.72
322_V356_E0.7430.72
494_K497_R0.7420.72
172_W490_M0.7420.72
381_T406_F0.7410.71
484_A628_L0.7400.71
247_T371_S0.7370.71
269_D272_K0.7370.71
193_E269_D0.7360.71
382_I386_I0.7350.71
260_W267_S0.7330.71
98_D101_D0.7320.71
373_L408_Q0.7310.70
517_V579_L0.7300.70
578_Y615_I0.7280.70
36_I41_K0.7280.70
168_H384_Y0.7270.70
464_A475_Q0.7260.70
46_S52_I0.7250.70
10_L18_S0.7230.70
152_V156_L0.7230.70
381_T405_Y0.7230.70
17_T22_Y0.7230.70
525_Y617_D0.7230.70
167_N291_Y0.7190.69
146_T275_Y0.7190.69
565_R568_E0.7180.69
402_Q425_H0.7160.69
136_K167_N0.7150.69
161_H567_E0.7150.69
167_N397_V0.7150.69
169_L268_I0.7100.68
260_W396_Y0.7100.68
394_S423_L0.7090.68
167_N275_Y0.7090.68
125_I184_T0.7090.68
135_A176_F0.7080.68
531_A596_L0.7080.68
386_I422_K0.7060.68
301_I366_V0.7050.68
435_E500_T0.7040.68
192_L262_R0.7030.67
459_A507_V0.7020.67
259_L263_F0.7020.67
128_D490_M0.7020.67
314_E368_S0.7010.67
286_N384_Y0.7010.67
49_S52_I0.7000.67
548_T593_N0.6970.67
107_I114_Y0.6950.67
236_D240_D0.6950.67
563_L567_E0.6920.66
39_E551_E0.6910.66
399_A437_S0.6910.66
128_D292_A0.6910.66
489_E499_T0.6910.66
135_A172_W0.6910.66
514_G625_I0.6890.66
17_T25_E0.6890.66
533_A610_K0.6890.66
59_P63_V0.6890.66
49_S64_A0.6880.66
245_W253_D0.6880.66
432_S506_S0.6880.66
463_I469_I0.6870.66
139_H451_V0.6860.66
430_L498_D0.6850.65
307_N417_G0.6840.65
269_D273_Q0.6840.65
32_E51_S0.6820.65
258_A262_R0.6820.65
512_D584_H0.6800.65
114_Y611_A0.6800.65
110_D113_E0.6780.65
174_V178_N0.6770.65
127_A395_V0.6770.65
36_I42_G0.6760.64
182_E206_Q0.6760.64
458_R503_I0.6760.64
177_G242_G0.6750.64
571_D574_P0.6740.64
387_E390_D0.6720.64
286_N389_Y0.6700.64
167_N425_H0.6690.64
617_D627_V0.6690.64
298_D305_I0.6690.64
395_V398_V0.6680.64
201_L447_T0.6670.63
366_V373_L0.6670.63
99_L550_V0.6670.63
453_D479_T0.6670.63
172_W177_G0.6650.63
300_I303_K0.6650.63
34_E45_S0.6610.63
447_T450_E0.6610.63
485_T509_L0.6600.63
13_I92_Y0.6580.62
151_A622_L0.6570.62
428_Y495_R0.6570.62
460_E474_A0.6570.62
598_A602_R0.6560.62
248_R255_D0.6550.62
469_I477_V0.6540.62
108_L611_A0.6530.62
562_V574_P0.6530.62
37_T42_G0.6530.62
586_F589_F0.6490.61
42_G86_E0.6490.61
20_A70_A0.6480.61
53_A60_P0.6470.61
186_F238_H0.6460.61
166_D286_N0.6460.61
46_S50_F0.6460.61
560_P564_E0.6460.61
255_D258_A0.6450.61
92_Y99_L0.6420.60
528_L531_A0.6410.60
538_D541_D0.6390.60
129_V145_N0.6380.60
184_T245_W0.6380.60
175_Q441_R0.6370.60
168_H385_R0.6360.60
379_L383_E0.6350.60
451_V506_S0.6350.60
427_D430_L0.6350.60
517_V616_F0.6350.60
551_E588_S0.6340.60
48_I52_I0.6340.60
138_L404_Q0.6330.59
17_T23_D0.6300.59
400_N403_N0.6300.59
298_D366_V0.6290.59
616_F627_V0.6280.59
178_N499_T0.6270.59
159_R564_E0.6270.59
139_H497_R0.6260.59
433_L438_M0.6260.59
455_A482_A0.6250.58
53_A56_A0.6240.58
184_T241_S0.6240.58
601_A605_R0.6230.58
31_I36_I0.6220.58
502_D505_E0.6220.58
179_L246_F0.6210.58
178_N363_F0.6200.58
12_G17_T0.6190.58
548_T585_V0.6190.58
48_I51_S0.6190.58
20_A24_Y0.6180.58
12_G75_G0.6180.58
392_D421_I0.6170.57
261_E264_R0.6160.57
169_L285_W0.6160.57
104_L611_A0.6150.57
65_A87_G0.6140.57
146_T167_N0.6130.57
310_A366_V0.6120.57
129_V150_D0.6120.57
246_F250_E0.6120.57
301_I310_A0.6110.57
94_A557_A0.6110.57
60_P64_A0.6100.57
16_A25_E0.6080.56
316_E319_Y0.6080.56
170_G267_S0.6080.56
181_H241_S0.6080.56
130_S134_I0.6070.56
166_D385_R0.6070.56
135_A177_G0.6050.56
50_F86_E0.6050.56
99_L557_A0.6040.56
294_E299_V0.6040.56
191_T199_H0.6040.56
519_Y523_R0.6030.56
314_E537_I0.6000.55
122_P162_D0.6000.55
284_V289_S0.6000.55
433_L436_G0.6000.55
431_I496_E0.5990.55
464_A471_D0.5980.55
429_G498_D0.5980.55
13_I46_S0.5970.55
37_T89_H0.5950.55
545_F601_A0.5940.55
135_A170_G0.5930.54
409_L412_A0.5910.54
16_A70_A0.5910.54
13_I98_D0.5910.54
249_L260_W0.5910.54
576_A579_L0.5910.54
507_V514_G0.5910.54
12_G22_Y0.5910.54
181_H207_F0.5900.54
278_L452_L0.5900.54
522_T526_S0.5890.54
11_A14_R0.5890.54
155_I237_Y0.5880.54
490_M499_T0.5870.54
431_I438_M0.5870.54
356_E359_D0.5870.54
303_K417_G0.5870.54
273_Q449_R0.5860.54
536_E568_E0.5850.53
135_A175_Q0.5850.53
455_A507_V0.5850.53
143_L278_L0.5840.53
518_Q628_L0.5840.53
566_C572_A0.5840.53
187_G190_A0.5840.53
473_E477_V0.5830.53
474_A478_A0.5830.53
172_W405_Y0.5820.53
297_N301_I0.5810.53
562_V575_L0.5810.53
254_E387_E0.5800.53
512_D580_L0.5800.53
578_Y619_G0.5790.53
238_H241_S0.5770.52
481_I526_S0.5770.52
137_P449_R0.5760.52
136_K425_H0.5760.52
537_I540_L0.5750.52
12_G80_V0.5740.52
317_S320_I0.5730.52
260_W405_Y0.5730.52
527_I586_F0.5730.52
406_F440_T0.5730.52
166_D391_A0.5720.52
10_L16_A0.5710.52
558_R562_V0.5710.52
129_V483_L0.5700.52
59_P87_G0.5700.52
172_W242_G0.5700.52
235_R241_S0.5670.51
514_G518_Q0.5670.51
16_A23_D0.5660.51
207_F210_R0.5650.51
549_D552_L0.5650.51
52_I67_I0.5650.51
20_A25_E0.5630.51
262_R266_V0.5620.51
385_R490_M0.5620.51
19_D22_Y0.5620.51
413_A418_Y0.5600.50
172_W287_G0.5600.50
114_Y615_I0.5600.50
68_A83_V0.5600.50
516_Y590_Y0.5590.50
17_T20_A0.5580.50
136_K429_G0.5570.50
316_E364_Y0.5560.50
174_V208_E0.5550.50
438_M444_Q0.5550.50
209_Q218_E0.5530.50
386_I391_A0.5520.49
33_L36_I0.5520.49
42_G93_H0.5520.49
145_N148_L0.5520.49
492_A573_A0.5510.49
19_D101_D0.5510.49
156_L159_R0.5500.49
200_L204_Y0.5500.49
363_F499_T0.5500.49
130_S260_W0.5500.49
132_P138_L0.5500.49
239_A243_K0.5490.49
600_N603_T0.5480.49
130_S176_F0.5480.49
135_A448_A0.5470.49
602_R610_K0.5470.49
19_D23_D0.5470.49
552_L593_N0.5460.49
136_K142_H0.5460.49
243_K482_A0.5450.49
135_A287_G0.5440.48
454_R507_V0.5430.48
25_E28_Q0.5430.48
57_G272_K0.5430.48
404_Q407_Q0.5430.48
172_W176_F0.5420.48
127_A165_R0.5410.48
33_L80_V0.5410.48
396_Y423_L0.5410.48
172_W385_R0.5410.48
375_G405_Y0.5400.48
115_G618_N0.5400.48
110_D614_Q0.5390.48
322_V360_F0.5390.48
379_L382_I0.5390.48
44_F50_F0.5380.48
250_E372_T0.5380.48
135_A267_S0.5370.48
31_I46_S0.5370.48
103_T106_T0.5370.48
494_K571_D0.5370.48
107_I115_G0.5370.48
322_V412_A0.5360.47
97_T464_A0.5360.47
398_V401_E0.5360.47
38_D42_G0.5360.47
10_L25_E0.5360.47
428_Y448_A0.5360.47
538_D603_T0.5350.47
561_L564_E0.5340.47
132_P406_F0.5340.47
249_L257_T0.5340.47
16_A74_N0.5340.47
16_A24_Y0.5320.47
413_A420_D0.5310.47
44_F465_E0.5310.47
132_P136_K0.5310.47
170_G490_M0.5310.47
140_V431_I0.5300.47
244_E536_E0.5300.47
75_G97_T0.5290.47
396_Y406_F0.5290.47
125_I393_Q0.5290.47
535_P539_D0.5280.46
235_R238_H0.5270.46
294_E384_Y0.5270.46
249_L448_A0.5260.46
46_S92_Y0.5250.46
158_A621_G0.5250.46
114_Y560_P0.5250.46
617_D621_G0.5240.46
525_Y627_V0.5240.46
166_D401_E0.5240.46
552_L615_I0.5240.46
110_D114_Y0.5230.46
607_L611_A0.5230.46
270_R274_T0.5220.46
19_D30_A0.5220.46
150_D609_T0.5220.46
480_K521_A0.5210.46
430_L437_S0.5210.46
168_H381_T0.5210.46
365_I412_A0.5200.45
576_A623_L0.5200.45
13_I19_D0.5200.45
146_T280_V0.5190.45
13_I18_S0.5190.45
127_A156_L0.5190.45
137_P201_L0.5190.45
135_A429_G0.5190.45
463_I478_A0.5180.45
590_Y596_L0.5170.45
166_D389_Y0.5170.45
120_A123_D0.5170.45
136_K260_W0.5170.45
239_A373_L0.5160.45
142_H429_G0.5160.45
382_I385_R0.5160.45
14_R29_S0.5160.45
376_T631_M0.5150.45
110_D539_D0.5150.45
146_T176_F0.5150.45
480_K630_E0.5140.45
316_E320_I0.5140.45
458_R462_I0.5140.45
522_T531_A0.5130.45
382_I409_L0.5130.45
356_E360_F0.5120.44
176_F291_Y0.5120.44
287_G290_F0.5120.44
119_D161_H0.5120.44
298_D372_T0.5110.44
18_S24_Y0.5110.44
157_E162_D0.5110.44
217_L239_A0.5100.44
455_A503_I0.5100.44
176_F287_G0.5100.44
114_Y618_N0.5100.44
540_L545_F0.5090.44
433_L506_S0.5090.44
480_K627_V0.5090.44
309_V416_M0.5080.44
455_A595_V0.5080.44
589_F612_T0.5070.44
406_F427_D0.5070.44
105_S543_S0.5070.44
286_N381_T0.5070.44
17_T48_I0.5060.44
291_Y294_E0.5060.44
541_D544_V0.5050.44
170_G405_Y0.5050.44
158_A622_L0.5040.43
101_D532_D0.5040.43
57_G387_E0.5040.43
98_D102_A0.5030.43
205_Q440_T0.5030.43
594_A602_R0.5020.43
543_S604_E0.5010.43
172_W260_W0.5000.43
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1f7uA 1 0.9033 100 0.288 Contact Map
4r3zB 1 0.8938 100 0.299 Contact Map
4q2tA 1 0.8938 100 0.307 Contact Map
4obyA 1 0.878 100 0.309 Contact Map
2zueA 1 0.9002 100 0.321 Contact Map
1iq0A 1 0.8621 100 0.337 Contact Map
3fnrA 1 0.7005 100 0.559 Contact Map
3tqoA 1 0.5816 100 0.752 Contact Map
3h99A 1 0.6339 100 0.773 Contact Map
3sp1A 1 0.5372 100 0.779 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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