SYR - HALSA - GREMLIN Contacts

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SYR - Arginine--tRNA ligase

UniProt:	Q9HHN2	Sequences: MLYNLRQELLAGIRAATSDAGYDYEVDQSAIELEDITDEEKGEFSSPISFSIAAAAGAPPVDVAAAIADAHRSNGLPAEVEAVTVEGGHINYHADTTDLADATLSTILRDGSEYGTRTDADPDTILADVSSPNIAKPLHVGHLRNTILSDAVMNILEARGHDVTRDNHLGDWGVQFGNLMHEYTEFGDEATLEDDAIEHLLDLYQQFEQRDSMLADLEDDETVTDQFADAVTEERDYHADSGKEWFTRLEQGDEDATALWERFRTVSIDRFKQTYDDLDVAFDVWNGESFYAQEGWNDVIIEKAIENDVAMRGEGESVYIPVYPDDYENVGDPQAADVDASLDRARQMREANDDLEDADFDPFYIVKSDGSTLYGTRDLATIEYRIEEYDADQSVYVVANEQNQYFQQLFVAARKMGYNDIKLKHIDYGLISLPEGSMSTRKGQIITAREVLDRAQDRAEEIIAEKGRIDDAEAQSVATKIALATIKYEMVAAKRERDTTFDIDESVALEGDTGPYVQYAATRGYSILDGADAAPEIDDLDPSVFNDTDVELLFELARYPLVLERCEERYDAAPLAHYLLQLAHVFNSFYHKNAVLDAENARTERLLLTKATTQIFDNGLGLLGIDVLEEM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	631 (558)
Sequences:	2654 (1753)
Seq/√Len:	74.2

ECOLI - SYR
BACSU - SYR
HALSA - SYR
SULSO - SYR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
124_T	162_D	5.923	1.00
579_L	619_G	5.681	1.00
302_E	306_E	4.635	1.00
185_E	241_S	4.004	1.00
65_A	69_D	3.994	1.00
277_D	479_T	3.994	1.00
277_D	453_D	3.850	1.00
155_I	622_L	3.769	1.00
248_R	253_D	3.746	1.00
58_A	66_A	3.537	1.00
460_E	475_Q	3.458	1.00
305_I	317_S	3.389	1.00
59_P	62_D	3.334	1.00
303_K	307_N	3.237	1.00
434_P	502_D	3.062	1.00
247_T	251_Q	3.046	1.00
82_A	93_H	2.954	1.00
452_L	486_I	2.952	1.00
244_E	248_R	2.911	1.00
398_V	406_F	2.884	1.00
157_E	165_R	2.858	1.00
68_A	90_I	2.824	1.00
272_K	276_D	2.767	1.00
464_A	474_A	2.707	1.00
524_G	609_T	2.695	1.00
521_A	627_V	2.595	1.00
145_N	428_Y	2.571	1.00
411_V	414_R	2.561	1.00
594_A	597_D	2.555	1.00
153_M	165_R	2.515	1.00
184_T	255_D	2.503	1.00
382_I	413_A	2.474	1.00
106_T	110_D	2.384	1.00
302_E	305_I	2.361	1.00
107_I	556_L	2.355	1.00
559_Y	618_N	2.306	1.00
96_T	550_V	2.258	1.00
151_A	154_N	2.257	1.00
206_Q	210_R	2.249	1.00
476_S	480_K	2.237	1.00
279_D	626_D	2.229	1.00
254_E	258_A	2.228	1.00
206_Q	209_Q	2.215	1.00
460_E	464_A	2.200	1.00
595_V	609_T	2.195	1.00
555_E	585_V	2.192	1.00
245_W	256_A	2.180	1.00
240_D	244_E	2.168	1.00
61_V	87_G	2.165	1.00
488_Y	512_D	2.156	1.00
159_R	567_E	2.151	1.00
521_A	525_Y	2.144	1.00
123_D	392_D	2.126	1.00
410_F	423_L	2.123	1.00
458_R	461_E	2.114	1.00
480_K	626_D	2.109	1.00
123_D	393_Q	2.090	1.00
424_K	570_Y	2.068	1.00
477_V	481_I	2.051	1.00
299_V	387_E	2.014	1.00
521_A	617_D	2.013	1.00
81_E	95_D	1.972	1.00
298_D	302_E	1.969	1.00
503_I	507_V	1.966	1.00
479_T	626_D	1.922	1.00
393_Q	424_K	1.918	1.00
261_E	265_T	1.906	1.00
305_I	366_V	1.848	1.00
578_Y	582_L	1.840	1.00
473_E	476_S	1.837	1.00
525_Y	613_T	1.835	1.00
124_T	164_T	1.834	1.00
127_A	152_V	1.832	1.00
563_L	622_L	1.832	1.00
521_A	613_T	1.816	1.00
130_S	275_Y	1.805	1.00
566_C	575_L	1.799	1.00
454_R	458_R	1.794	1.00
458_R	504_D	1.785	1.00
586_F	609_T	1.782	1.00
529_D	629_E	1.765	1.00
363_F	375_G	1.762	1.00
476_S	479_T	1.725	1.00
254_E	261_E	1.721	1.00
113_E	116_T	1.716	1.00
130_S	146_T	1.706	1.00
456_Q	479_T	1.704	1.00
150_D	154_N	1.701	1.00
158_A	618_N	1.699	1.00
555_E	558_R	1.693	1.00
66_A	69_D	1.688	1.00
484_A	518_Q	1.683	1.00
401_E	430_L	1.670	1.00
614_Q	618_N	1.644	1.00
384_Y	388_E	1.644	1.00
550_V	554_F	1.640	1.00
303_K	418_Y	1.630	1.00
618_N	621_G	1.600	0.99
277_D	456_Q	1.592	0.99
265_T	269_D	1.567	0.99
185_E	210_R	1.564	0.99
44_F	94_A	1.560	0.99
525_Y	629_E	1.558	0.99
33_L	44_F	1.556	0.99
432_S	498_D	1.538	0.99
96_T	547_D	1.534	0.99
125_I	161_H	1.515	0.99
312_R	317_S	1.511	0.99
610_K	614_Q	1.510	0.99
520_A	587_N	1.487	0.99
546_N	549_D	1.486	0.99
16_A	20_A	1.482	0.99
13_I	16_A	1.479	0.99
67_I	90_I	1.473	0.99
284_V	389_Y	1.468	0.99
395_V	426_I	1.467	0.99
373_L	376_T	1.466	0.99
310_A	317_S	1.464	0.99
62_D	66_A	1.457	0.99
156_L	570_Y	1.452	0.99
186_F	210_R	1.451	0.99
299_V	302_E	1.444	0.99
156_L	567_E	1.438	0.99
158_A	559_Y	1.437	0.99
15_A	19_D	1.424	0.99
558_R	561_L	1.422	0.99
556_L	615_I	1.422	0.99
456_Q	475_Q	1.421	0.99
152_V	426_I	1.418	0.99
300_I	383_E	1.416	0.99
579_L	616_F	1.415	0.99
188_D	191_T	1.414	0.99
274_T	449_R	1.413	0.99
596_L	602_R	1.412	0.99
37_T	41_K	1.404	0.99
457_D	461_E	1.402	0.99
531_A	606_L	1.399	0.99
527_I	595_V	1.397	0.99
159_R	563_L	1.392	0.98
303_K	306_E	1.385	0.98
257_T	261_E	1.385	0.98
81_E	96_T	1.377	0.98
453_D	457_D	1.377	0.98
524_G	586_F	1.373	0.98
61_V	65_A	1.371	0.98
515_P	631_M	1.367	0.98
267_S	271_F	1.364	0.98
542_P	545_F	1.348	0.98
552_L	612_T	1.342	0.98
189_E	193_E	1.338	0.98
244_E	247_T	1.331	0.98
84_T	93_H	1.328	0.98
470_D	473_E	1.326	0.98
101_D	105_S	1.326	0.98
565_R	569_R	1.324	0.98
488_Y	580_L	1.323	0.98
299_V	303_K	1.323	0.98
253_D	256_A	1.321	0.98
582_L	612_T	1.318	0.98
304_A	416_M	1.316	0.98
207_F	238_H	1.313	0.98
277_D	452_L	1.310	0.98
129_V	165_R	1.303	0.98
155_I	566_C	1.301	0.98
363_F	409_L	1.301	0.98
575_L	619_G	1.300	0.98
363_F	412_A	1.300	0.98
580_L	584_H	1.293	0.98
122_P	161_H	1.293	0.98
303_K	383_E	1.292	0.98
181_H	242_G	1.289	0.97
383_E	387_E	1.285	0.97
364_Y	375_G	1.285	0.97
68_A	85_V	1.284	0.97
480_K	628_L	1.273	0.97
317_S	366_V	1.270	0.97
411_V	415_K	1.270	0.97
549_D	605_R	1.268	0.97
58_A	62_D	1.264	0.97
472_A	630_E	1.258	0.97
166_D	381_T	1.255	0.97
150_D	487_K	1.251	0.97
319_Y	412_A	1.251	0.97
12_G	15_A	1.249	0.97
154_N	621_G	1.247	0.97
485_T	515_P	1.244	0.97
61_V	85_V	1.242	0.97
75_G	95_D	1.237	0.97
456_Q	483_L	1.236	0.97
195_D	198_E	1.230	0.97
290_F	384_Y	1.230	0.97
399_A	403_N	1.223	0.97
456_Q	460_E	1.219	0.96
382_I	396_Y	1.215	0.96
127_A	163_V	1.215	0.96
181_H	245_W	1.210	0.96
129_V	153_M	1.200	0.96
395_V	570_Y	1.197	0.96
126_L	391_A	1.196	0.96
199_H	203_L	1.192	0.96
358_A	415_K	1.192	0.96
400_N	427_D	1.188	0.96
301_I	365_I	1.186	0.96
462_I	465_E	1.184	0.96
22_Y	25_E	1.184	0.96
155_I	567_E	1.176	0.96
471_D	475_Q	1.163	0.95
375_G	412_A	1.162	0.95
597_D	602_R	1.161	0.95
199_H	202_D	1.160	0.95
43_E	554_F	1.159	0.95
301_I	305_I	1.159	0.95
198_E	201_L	1.158	0.95
202_D	206_Q	1.157	0.95
140_V	451_V	1.153	0.95
509_L	515_P	1.152	0.95
556_L	582_L	1.151	0.95
150_D	624_G	1.146	0.95
56_A	63_V	1.146	0.95
620_L	625_I	1.145	0.95
598_A	601_A	1.142	0.95
107_I	611_A	1.139	0.95
58_A	63_V	1.138	0.95
546_N	593_N	1.134	0.95
401_E	437_S	1.130	0.95
589_F	593_N	1.126	0.94
555_E	581_Q	1.122	0.94
201_L	445_I	1.119	0.94
127_A	153_M	1.112	0.94
399_A	430_L	1.106	0.94
83_V	92_Y	1.104	0.94
305_I	310_A	1.100	0.94
492_A	505_E	1.095	0.94
593_N	605_R	1.092	0.94
154_N	157_E	1.091	0.94
266_V	269_D	1.088	0.93
11_A	15_A	1.083	0.93
182_E	185_E	1.081	0.93
237_Y	240_D	1.078	0.93
397_V	426_I	1.077	0.93
481_I	515_P	1.075	0.93
547_D	551_E	1.074	0.93
379_L	413_A	1.073	0.93
460_E	478_A	1.072	0.93
12_G	16_A	1.069	0.93
240_D	243_K	1.065	0.93
461_E	464_A	1.059	0.92
375_G	409_L	1.058	0.92
16_A	19_D	1.055	0.92
38_D	41_K	1.055	0.92
107_I	615_I	1.055	0.92
18_S	25_E	1.054	0.92
456_Q	482_A	1.053	0.92
519_Y	587_N	1.051	0.92
305_I	312_R	1.051	0.92
182_E	203_L	1.049	0.92
43_E	550_V	1.047	0.92
311_M	320_I	1.047	0.92
361_D	404_Q	1.047	0.92
139_H	431_I	1.045	0.92
303_K	416_M	1.045	0.92
455_A	458_R	1.036	0.92
300_I	380_A	1.035	0.92
130_S	167_N	1.032	0.91
610_K	613_T	1.032	0.91
104_L	108_L	1.031	0.91
178_N	207_F	1.029	0.91
126_L	394_S	1.024	0.91
143_L	490_M	1.024	0.91
454_R	503_I	1.012	0.91
594_A	598_A	1.011	0.91
385_R	396_Y	1.009	0.91
461_E	465_E	1.005	0.90
157_E	281_A	1.003	0.90
85_V	88_G	1.002	0.90
620_L	627_V	1.002	0.90
73_S	80_V	1.000	0.90
521_A	629_E	1.000	0.90
404_Q	408_Q	0.997	0.90
586_F	590_Y	0.997	0.90
152_V	397_V	0.995	0.90
395_V	424_K	0.993	0.90
385_R	394_S	0.992	0.90
52_I	63_V	0.990	0.90
393_Q	422_K	0.990	0.90
10_L	14_R	0.989	0.90
94_A	99_L	0.989	0.90
313_G	316_E	0.986	0.90
463_I	467_G	0.984	0.89
61_V	86_E	0.983	0.89
391_A	394_S	0.978	0.89
168_H	291_Y	0.978	0.89
313_G	318_V	0.977	0.89
276_D	281_A	0.977	0.89
548_T	592_K	0.976	0.89
116_T	158_A	0.973	0.89
157_E	163_V	0.972	0.89
564_E	568_E	0.968	0.89
555_E	582_L	0.968	0.89
559_Y	619_G	0.964	0.88
182_E	207_F	0.964	0.88
471_D	474_A	0.962	0.88
313_G	362_P	0.962	0.88
476_S	626_D	0.961	0.88
270_R	273_Q	0.959	0.88
108_L	607_L	0.954	0.88
303_K	387_E	0.950	0.88
71_H	83_V	0.947	0.88
398_V	427_D	0.944	0.87
210_R	235_R	0.941	0.87
16_A	22_Y	0.939	0.87
613_T	617_D	0.939	0.87
14_R	18_S	0.936	0.87
144_R	490_M	0.934	0.87
403_N	407_Q	0.931	0.87
36_I	45_S	0.930	0.87
312_R	315_G	0.929	0.87
10_L	13_I	0.929	0.87
35_D	558_R	0.920	0.86
272_K	285_W	0.914	0.86
559_Y	563_L	0.913	0.86
461_E	504_D	0.912	0.85
527_I	609_T	0.911	0.85
559_Y	615_I	0.910	0.85
300_I	379_L	0.907	0.85
478_A	482_A	0.906	0.85
426_I	570_Y	0.905	0.85
480_K	484_A	0.905	0.85
552_L	582_L	0.905	0.85
403_N	427_D	0.903	0.85
364_Y	373_L	0.902	0.85
529_D	630_E	0.901	0.85
541_D	604_E	0.900	0.85
13_I	25_E	0.899	0.85
617_D	629_E	0.899	0.85
526_S	529_D	0.897	0.85
611_A	614_Q	0.896	0.84
189_E	262_R	0.895	0.84
369_D	373_L	0.893	0.84
19_D	70_A	0.887	0.84
72_R	82_A	0.884	0.84
210_R	238_H	0.881	0.83
80_V	92_Y	0.876	0.83
522_T	525_Y	0.876	0.83
64_A	85_V	0.873	0.83
454_R	457_D	0.873	0.83
113_E	158_A	0.873	0.83
181_H	185_E	0.872	0.83
357_D	415_K	0.871	0.83
39_E	42_G	0.870	0.83
549_D	593_N	0.869	0.83
463_I	466_K	0.869	0.83
118_T	121_D	0.868	0.83
541_D	545_F	0.866	0.82
297_N	377_R	0.865	0.82
209_Q	219_D	0.864	0.82
396_Y	410_F	0.861	0.82
66_A	70_A	0.860	0.82
372_T	377_R	0.860	0.82
143_L	147_I	0.856	0.82
521_A	628_L	0.856	0.82
427_D	496_E	0.852	0.81
291_Y	384_Y	0.842	0.81
132_P	260_W	0.841	0.81
398_V	425_H	0.841	0.81
245_W	248_R	0.839	0.80
286_N	289_S	0.839	0.80
291_Y	381_T	0.839	0.80
15_A	18_S	0.839	0.80
62_D	65_A	0.836	0.80
252_G	257_T	0.836	0.80
525_Y	529_D	0.835	0.80
191_T	194_D	0.833	0.80
251_Q	371_S	0.832	0.80
80_V	83_V	0.831	0.80
49_S	67_I	0.831	0.80
396_Y	405_Y	0.829	0.80
562_V	565_R	0.829	0.80
136_K	402_Q	0.828	0.79
119_D	564_E	0.828	0.79
13_I	22_Y	0.828	0.79
161_H	393_Q	0.826	0.79
13_I	67_I	0.824	0.79
250_E	377_R	0.823	0.79
125_I	156_L	0.823	0.79
132_P	167_N	0.820	0.79
533_A	602_R	0.820	0.79
41_K	45_S	0.816	0.78
210_R	219_D	0.816	0.78
544_V	601_A	0.812	0.78
462_I	466_K	0.811	0.78
382_I	420_D	0.810	0.78
175_Q	440_T	0.810	0.78
468_R	471_D	0.809	0.78
381_T	385_R	0.809	0.78
386_I	390_D	0.807	0.78
268_I	284_V	0.807	0.78
548_T	588_S	0.807	0.78
524_G	613_T	0.807	0.78
114_Y	614_Q	0.801	0.77
473_E	630_E	0.794	0.77
166_D	284_V	0.793	0.76
147_I	280_V	0.790	0.76
383_E	418_Y	0.790	0.76
386_I	394_S	0.790	0.76
519_Y	590_Y	0.788	0.76
358_A	411_V	0.788	0.76
536_E	539_D	0.787	0.76
95_D	98_D	0.787	0.76
49_S	63_V	0.786	0.76
301_I	304_A	0.785	0.76
432_S	500_T	0.785	0.76
172_W	292_A	0.784	0.76
455_A	486_I	0.783	0.76
183_Y	263_F	0.783	0.76
153_M	157_E	0.776	0.75
384_Y	389_Y	0.776	0.75
46_S	49_S	0.775	0.75
174_V	367_K	0.774	0.75
147_I	278_L	0.772	0.75
178_N	208_E	0.772	0.75
105_S	109_R	0.770	0.74
236_D	239_A	0.768	0.74
117_R	159_R	0.767	0.74
482_A	486_I	0.763	0.74
182_E	186_F	0.760	0.73
556_L	612_T	0.759	0.73
147_I	490_M	0.758	0.73
439_S	442_K	0.757	0.73
143_L	172_W	0.757	0.73
14_R	25_E	0.755	0.73
145_N	490_M	0.755	0.73
597_D	600_N	0.755	0.73
208_E	218_E	0.754	0.73
313_G	375_G	0.752	0.73
132_P	275_Y	0.752	0.73
148_L	428_Y	0.752	0.73
123_D	161_H	0.752	0.73
474_A	477_V	0.751	0.73
47_P	50_F	0.748	0.72
126_L	166_D	0.747	0.72
135_A	490_M	0.747	0.72
127_A	397_V	0.746	0.72
181_H	238_H	0.744	0.72
108_L	610_K	0.744	0.72
322_V	356_E	0.743	0.72
494_K	497_R	0.742	0.72
172_W	490_M	0.742	0.72
381_T	406_F	0.741	0.71
484_A	628_L	0.740	0.71
247_T	371_S	0.737	0.71
269_D	272_K	0.737	0.71
193_E	269_D	0.736	0.71
382_I	386_I	0.735	0.71
260_W	267_S	0.733	0.71
98_D	101_D	0.732	0.71
373_L	408_Q	0.731	0.70
517_V	579_L	0.730	0.70
578_Y	615_I	0.728	0.70
36_I	41_K	0.728	0.70
168_H	384_Y	0.727	0.70
464_A	475_Q	0.726	0.70
46_S	52_I	0.725	0.70
10_L	18_S	0.723	0.70
152_V	156_L	0.723	0.70
381_T	405_Y	0.723	0.70
17_T	22_Y	0.723	0.70
525_Y	617_D	0.723	0.70
167_N	291_Y	0.719	0.69
146_T	275_Y	0.719	0.69
565_R	568_E	0.718	0.69
402_Q	425_H	0.716	0.69
136_K	167_N	0.715	0.69
161_H	567_E	0.715	0.69
167_N	397_V	0.715	0.69
169_L	268_I	0.710	0.68
260_W	396_Y	0.710	0.68
394_S	423_L	0.709	0.68
167_N	275_Y	0.709	0.68
125_I	184_T	0.709	0.68
135_A	176_F	0.708	0.68
531_A	596_L	0.708	0.68
386_I	422_K	0.706	0.68
301_I	366_V	0.705	0.68
435_E	500_T	0.704	0.68
192_L	262_R	0.703	0.67
459_A	507_V	0.702	0.67
259_L	263_F	0.702	0.67
128_D	490_M	0.702	0.67
314_E	368_S	0.701	0.67
286_N	384_Y	0.701	0.67
49_S	52_I	0.700	0.67
548_T	593_N	0.697	0.67
107_I	114_Y	0.695	0.67
236_D	240_D	0.695	0.67
563_L	567_E	0.692	0.66
39_E	551_E	0.691	0.66
399_A	437_S	0.691	0.66
128_D	292_A	0.691	0.66
489_E	499_T	0.691	0.66
135_A	172_W	0.691	0.66
514_G	625_I	0.689	0.66
17_T	25_E	0.689	0.66
533_A	610_K	0.689	0.66
59_P	63_V	0.689	0.66
49_S	64_A	0.688	0.66
245_W	253_D	0.688	0.66
432_S	506_S	0.688	0.66
463_I	469_I	0.687	0.66
139_H	451_V	0.686	0.66
430_L	498_D	0.685	0.65
307_N	417_G	0.684	0.65
269_D	273_Q	0.684	0.65
32_E	51_S	0.682	0.65
258_A	262_R	0.682	0.65
512_D	584_H	0.680	0.65
114_Y	611_A	0.680	0.65
110_D	113_E	0.678	0.65
174_V	178_N	0.677	0.65
127_A	395_V	0.677	0.65
36_I	42_G	0.676	0.64
182_E	206_Q	0.676	0.64
458_R	503_I	0.676	0.64
177_G	242_G	0.675	0.64
571_D	574_P	0.674	0.64
387_E	390_D	0.672	0.64
286_N	389_Y	0.670	0.64
167_N	425_H	0.669	0.64
617_D	627_V	0.669	0.64
298_D	305_I	0.669	0.64
395_V	398_V	0.668	0.64
201_L	447_T	0.667	0.63
366_V	373_L	0.667	0.63
99_L	550_V	0.667	0.63
453_D	479_T	0.667	0.63
172_W	177_G	0.665	0.63
300_I	303_K	0.665	0.63
34_E	45_S	0.661	0.63
447_T	450_E	0.661	0.63
485_T	509_L	0.660	0.63
13_I	92_Y	0.658	0.62
151_A	622_L	0.657	0.62
428_Y	495_R	0.657	0.62
460_E	474_A	0.657	0.62
598_A	602_R	0.656	0.62
248_R	255_D	0.655	0.62
469_I	477_V	0.654	0.62
108_L	611_A	0.653	0.62
562_V	574_P	0.653	0.62
37_T	42_G	0.653	0.62
586_F	589_F	0.649	0.61
42_G	86_E	0.649	0.61
20_A	70_A	0.648	0.61
53_A	60_P	0.647	0.61
186_F	238_H	0.646	0.61
166_D	286_N	0.646	0.61
46_S	50_F	0.646	0.61
560_P	564_E	0.646	0.61
255_D	258_A	0.645	0.61
92_Y	99_L	0.642	0.60
528_L	531_A	0.641	0.60
538_D	541_D	0.639	0.60
129_V	145_N	0.638	0.60
184_T	245_W	0.638	0.60
175_Q	441_R	0.637	0.60
168_H	385_R	0.636	0.60
379_L	383_E	0.635	0.60
451_V	506_S	0.635	0.60
427_D	430_L	0.635	0.60
517_V	616_F	0.635	0.60
551_E	588_S	0.634	0.60
48_I	52_I	0.634	0.60
138_L	404_Q	0.633	0.59
17_T	23_D	0.630	0.59
400_N	403_N	0.630	0.59
298_D	366_V	0.629	0.59
616_F	627_V	0.628	0.59
178_N	499_T	0.627	0.59
159_R	564_E	0.627	0.59
139_H	497_R	0.626	0.59
433_L	438_M	0.626	0.59
455_A	482_A	0.625	0.58
53_A	56_A	0.624	0.58
184_T	241_S	0.624	0.58
601_A	605_R	0.623	0.58
31_I	36_I	0.622	0.58
502_D	505_E	0.622	0.58
179_L	246_F	0.621	0.58
178_N	363_F	0.620	0.58
12_G	17_T	0.619	0.58
548_T	585_V	0.619	0.58
48_I	51_S	0.619	0.58
20_A	24_Y	0.618	0.58
12_G	75_G	0.618	0.58
392_D	421_I	0.617	0.57
261_E	264_R	0.616	0.57
169_L	285_W	0.616	0.57
104_L	611_A	0.615	0.57
65_A	87_G	0.614	0.57
146_T	167_N	0.613	0.57
310_A	366_V	0.612	0.57
129_V	150_D	0.612	0.57
246_F	250_E	0.612	0.57
301_I	310_A	0.611	0.57
94_A	557_A	0.611	0.57
60_P	64_A	0.610	0.57
16_A	25_E	0.608	0.56
316_E	319_Y	0.608	0.56
170_G	267_S	0.608	0.56
181_H	241_S	0.608	0.56
130_S	134_I	0.607	0.56
166_D	385_R	0.607	0.56
135_A	177_G	0.605	0.56
50_F	86_E	0.605	0.56
99_L	557_A	0.604	0.56
294_E	299_V	0.604	0.56
191_T	199_H	0.604	0.56
519_Y	523_R	0.603	0.56
314_E	537_I	0.600	0.55
122_P	162_D	0.600	0.55
284_V	289_S	0.600	0.55
433_L	436_G	0.600	0.55
431_I	496_E	0.599	0.55
464_A	471_D	0.598	0.55
429_G	498_D	0.598	0.55
13_I	46_S	0.597	0.55
37_T	89_H	0.595	0.55
545_F	601_A	0.594	0.55
135_A	170_G	0.593	0.54
409_L	412_A	0.591	0.54
16_A	70_A	0.591	0.54
13_I	98_D	0.591	0.54
249_L	260_W	0.591	0.54
576_A	579_L	0.591	0.54
507_V	514_G	0.591	0.54
12_G	22_Y	0.591	0.54
181_H	207_F	0.590	0.54
278_L	452_L	0.590	0.54
522_T	526_S	0.589	0.54
11_A	14_R	0.589	0.54
155_I	237_Y	0.588	0.54
490_M	499_T	0.587	0.54
431_I	438_M	0.587	0.54
356_E	359_D	0.587	0.54
303_K	417_G	0.587	0.54
273_Q	449_R	0.586	0.54
536_E	568_E	0.585	0.53
135_A	175_Q	0.585	0.53
455_A	507_V	0.585	0.53
143_L	278_L	0.584	0.53
518_Q	628_L	0.584	0.53
566_C	572_A	0.584	0.53
187_G	190_A	0.584	0.53
473_E	477_V	0.583	0.53
474_A	478_A	0.583	0.53
172_W	405_Y	0.582	0.53
297_N	301_I	0.581	0.53
562_V	575_L	0.581	0.53
254_E	387_E	0.580	0.53
512_D	580_L	0.580	0.53
578_Y	619_G	0.579	0.53
238_H	241_S	0.577	0.52
481_I	526_S	0.577	0.52
137_P	449_R	0.576	0.52
136_K	425_H	0.576	0.52
537_I	540_L	0.575	0.52
12_G	80_V	0.574	0.52
317_S	320_I	0.573	0.52
260_W	405_Y	0.573	0.52
527_I	586_F	0.573	0.52
406_F	440_T	0.573	0.52
166_D	391_A	0.572	0.52
10_L	16_A	0.571	0.52
558_R	562_V	0.571	0.52
129_V	483_L	0.570	0.52
59_P	87_G	0.570	0.52
172_W	242_G	0.570	0.52
235_R	241_S	0.567	0.51
514_G	518_Q	0.567	0.51
16_A	23_D	0.566	0.51
207_F	210_R	0.565	0.51
549_D	552_L	0.565	0.51
52_I	67_I	0.565	0.51
20_A	25_E	0.563	0.51
262_R	266_V	0.562	0.51
385_R	490_M	0.562	0.51
19_D	22_Y	0.562	0.51
413_A	418_Y	0.560	0.50
172_W	287_G	0.560	0.50
114_Y	615_I	0.560	0.50
68_A	83_V	0.560	0.50
516_Y	590_Y	0.559	0.50
17_T	20_A	0.558	0.50
136_K	429_G	0.557	0.50
316_E	364_Y	0.556	0.50
174_V	208_E	0.555	0.50
438_M	444_Q	0.555	0.50
209_Q	218_E	0.553	0.50
386_I	391_A	0.552	0.49
33_L	36_I	0.552	0.49
42_G	93_H	0.552	0.49
145_N	148_L	0.552	0.49
492_A	573_A	0.551	0.49
19_D	101_D	0.551	0.49
156_L	159_R	0.550	0.49
200_L	204_Y	0.550	0.49
363_F	499_T	0.550	0.49
130_S	260_W	0.550	0.49
132_P	138_L	0.550	0.49
239_A	243_K	0.549	0.49
600_N	603_T	0.548	0.49
130_S	176_F	0.548	0.49
135_A	448_A	0.547	0.49
602_R	610_K	0.547	0.49
19_D	23_D	0.547	0.49
552_L	593_N	0.546	0.49
136_K	142_H	0.546	0.49
243_K	482_A	0.545	0.49
135_A	287_G	0.544	0.48
454_R	507_V	0.543	0.48
25_E	28_Q	0.543	0.48
57_G	272_K	0.543	0.48
404_Q	407_Q	0.543	0.48
172_W	176_F	0.542	0.48
127_A	165_R	0.541	0.48
33_L	80_V	0.541	0.48
396_Y	423_L	0.541	0.48
172_W	385_R	0.541	0.48
375_G	405_Y	0.540	0.48
115_G	618_N	0.540	0.48
110_D	614_Q	0.539	0.48
322_V	360_F	0.539	0.48
379_L	382_I	0.539	0.48
44_F	50_F	0.538	0.48
250_E	372_T	0.538	0.48
135_A	267_S	0.537	0.48
31_I	46_S	0.537	0.48
103_T	106_T	0.537	0.48
494_K	571_D	0.537	0.48
107_I	115_G	0.537	0.48
322_V	412_A	0.536	0.47
97_T	464_A	0.536	0.47
398_V	401_E	0.536	0.47
38_D	42_G	0.536	0.47
10_L	25_E	0.536	0.47
428_Y	448_A	0.536	0.47
538_D	603_T	0.535	0.47
561_L	564_E	0.534	0.47
132_P	406_F	0.534	0.47
249_L	257_T	0.534	0.47
16_A	74_N	0.534	0.47
16_A	24_Y	0.532	0.47
413_A	420_D	0.531	0.47
44_F	465_E	0.531	0.47
132_P	136_K	0.531	0.47
170_G	490_M	0.531	0.47
140_V	431_I	0.530	0.47
244_E	536_E	0.530	0.47
75_G	97_T	0.529	0.47
396_Y	406_F	0.529	0.47
125_I	393_Q	0.529	0.47
535_P	539_D	0.528	0.46
235_R	238_H	0.527	0.46
294_E	384_Y	0.527	0.46
249_L	448_A	0.526	0.46
46_S	92_Y	0.525	0.46
158_A	621_G	0.525	0.46
114_Y	560_P	0.525	0.46
617_D	621_G	0.524	0.46
525_Y	627_V	0.524	0.46
166_D	401_E	0.524	0.46
552_L	615_I	0.524	0.46
110_D	114_Y	0.523	0.46
607_L	611_A	0.523	0.46
270_R	274_T	0.522	0.46
19_D	30_A	0.522	0.46
150_D	609_T	0.522	0.46
480_K	521_A	0.521	0.46
430_L	437_S	0.521	0.46
168_H	381_T	0.521	0.46
365_I	412_A	0.520	0.45
576_A	623_L	0.520	0.45
13_I	19_D	0.520	0.45
146_T	280_V	0.519	0.45
13_I	18_S	0.519	0.45
127_A	156_L	0.519	0.45
137_P	201_L	0.519	0.45
135_A	429_G	0.519	0.45
463_I	478_A	0.518	0.45
590_Y	596_L	0.517	0.45
166_D	389_Y	0.517	0.45
120_A	123_D	0.517	0.45
136_K	260_W	0.517	0.45
239_A	373_L	0.516	0.45
142_H	429_G	0.516	0.45
382_I	385_R	0.516	0.45
14_R	29_S	0.516	0.45
376_T	631_M	0.515	0.45
110_D	539_D	0.515	0.45
146_T	176_F	0.515	0.45
480_K	630_E	0.514	0.45
316_E	320_I	0.514	0.45
458_R	462_I	0.514	0.45
522_T	531_A	0.513	0.45
382_I	409_L	0.513	0.45
356_E	360_F	0.512	0.44
176_F	291_Y	0.512	0.44
287_G	290_F	0.512	0.44
119_D	161_H	0.512	0.44
298_D	372_T	0.511	0.44
18_S	24_Y	0.511	0.44
157_E	162_D	0.511	0.44
217_L	239_A	0.510	0.44
455_A	503_I	0.510	0.44
176_F	287_G	0.510	0.44
114_Y	618_N	0.510	0.44
540_L	545_F	0.509	0.44
433_L	506_S	0.509	0.44
480_K	627_V	0.509	0.44
309_V	416_M	0.508	0.44
455_A	595_V	0.508	0.44
589_F	612_T	0.507	0.44
406_F	427_D	0.507	0.44
105_S	543_S	0.507	0.44
286_N	381_T	0.507	0.44
17_T	48_I	0.506	0.44
291_Y	294_E	0.506	0.44
541_D	544_V	0.505	0.44
170_G	405_Y	0.505	0.44
158_A	622_L	0.504	0.43
101_D	532_D	0.504	0.43
57_G	387_E	0.504	0.43
98_D	102_A	0.503	0.43
205_Q	440_T	0.503	0.43
594_A	602_R	0.502	0.43
543_S	604_E	0.501	0.43
172_W	260_W	0.500	0.43

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1f7uA	1	0.9033	100	0.288	Contact Map
4r3zB	1	0.8938	100	0.299	Contact Map
4q2tA	1	0.8938	100	0.307	Contact Map
4obyA	1	0.878	100	0.309	Contact Map
2zueA	1	0.9002	100	0.321	Contact Map
1iq0A	1	0.8621	100	0.337	Contact Map
3fnrA	1	0.7005	100	0.559	Contact Map
3tqoA	1	0.5816	100	0.752	Contact Map
3h99A	1	0.6339	100	0.773	Contact Map
3sp1A	1	0.5372	100	0.779	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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