ARCD - HALSA - GREMLIN Contacts

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ARCD - Arginine/ornithine antiporter ArcD

UniProt:	Q9HHN1	Sequences: MVEFEPRSYEDFDPEKRPSFGQALLPIAGMITFLAVGIVLLGLDAQMPLLWGIAFTGVIARYGWGYTWDELFDGISNSIVMGLGAIFILFIIYMLIASWVDAGTIPFIMYWGLEFLTPAVFVPLAALLSFVVATAIGSSWTTAGSLGIALVGIGSGLGIPAPLTAGAILSGVYMGDKQSPLSDTTLLASGVSDVDLWDHVRGMFPNTIIVGVISLALYAVLGLMAETGGTGGTGAEVAQIQGGLAGTYTLSVLVLLPLVITFGLAIKGYPALPSLGAGVFSAAGVSILIQGRGFAEAWQIIYSGTGPKTGVDLVNNLLSTGGLEGSIWVITIVFGALSIGGILEATGVLSVIAHNTAKAVDSVGGATLVTALGPLVINALTADQYMSIVIPGMTFRDLNDEYDLDGTSLSRTLEETGTVSEPMIPWNSGGVFMASALGVPVLSYLPYYFVGILSPILVVIMGFTGWKMYMKDPEESPEESADTAA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	485 (424)
Sequences:	2524 (1686)
Seq/√Len:	81.9

BACSU - MLEN NHAC
HALSA - ARCD Q9HNF7 Q9HS26

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
217_L	449_F	6.055	1.00
138_S	141_T	4.643	1.00
260_I	281_S	3.983	1.00
364_G	463_F	3.874	1.00
400_D	406_G	3.632	1.00
154_G	164_T	3.459	1.00
212_V	216_A	3.433	1.00
130_F	211_G	3.160	1.00
143_A	433_M	3.108	1.00
67_T	70_E	3.042	1.00
362_S	365_G	2.924	1.00
202_G	408_S	2.921	1.00
293_G	296_E	2.907	1.00
123_P	219_A	2.867	1.00
123_P	215_L	2.784	1.00
151_V	161_A	2.643	1.00
178_Q	204_F	2.569	1.00
213_I	453_L	2.568	1.00
370_T	399_N	2.546	1.00
364_G	462_G	2.489	1.00
355_N	358_K	2.457	1.00
98_S	301_I	2.435	1.00
125_A	150_L	2.430	1.00
90_F	323_L	2.414	1.00
278_G	282_A	2.384	1.00
122_V	163_L	2.374	1.00
195_D	198_D	2.374	1.00
368_L	463_F	2.324	1.00
210_V	453_L	2.306	1.00
283_A	297_A	2.262	1.00
371_A	416_T	2.248	1.00
261_T	278_G	2.210	1.00
114_E	241_Q	2.191	1.00
448_Y	451_G	2.182	1.00
344_E	393_M	2.179	1.00
263_G	267_K	2.173	1.00
375_L	420_S	2.160	1.00
107_F	250_L	2.141	1.00
378_N	420_S	2.130	1.00
193_D	406_G	2.083	1.00
77_N	345_A	2.077	1.00
251_S	254_V	2.067	1.00
379_A	424_I	2.063	1.00
126_A	211_G	2.052	1.00
257_P	261_T	2.044	1.00
159_I	164_T	2.042	1.00
373_G	395_F	2.013	1.00
350_S	354_H	1.943	1.00
213_I	457_L	1.927	1.00
216_A	220_V	1.920	1.00
249_T	252_V	1.920	1.00
258_L	261_T	1.898	1.00
404_L	408_S	1.889	1.00
250_L	254_V	1.871	1.00
107_F	111_W	1.869	1.00
254_V	258_L	1.865	1.00
194_V	406_G	1.860	1.00
371_A	459_V	1.835	1.00
219_A	223_L	1.832	1.00
214_S	218_Y	1.808	1.00
60_A	71_L	1.808	1.00
101_D	300_I	1.801	1.00
167_A	218_Y	1.799	1.00
456_I	460_I	1.772	1.00
264_L	277_A	1.766	1.00
441_V	445_L	1.754	1.00
74_G	345_A	1.753	1.00
434_A	441_V	1.751	1.00
98_S	279_V	1.731	1.00
104_T	257_P	1.712	1.00
96_I	144_G	1.701	1.00
77_N	80_V	1.692	1.00
169_L	430_G	1.684	1.00
244_L	250_L	1.657	1.00
29_G	55_F	1.632	1.00
163_L	221_L	1.613	1.00
206_N	415_E	1.598	1.00
449_F	453_L	1.597	1.00
254_V	257_P	1.588	1.00
460_I	464_T	1.568	1.00
36_V	41_L	1.567	1.00
107_F	255_L	1.558	1.00
327_I	331_T	1.556	1.00
449_F	452_I	1.553	1.00
302_Y	324_E	1.552	1.00
299_Q	303_S	1.540	1.00
189_S	194_V	1.539	1.00
432_F	436_A	1.530	0.99
361_D	365_G	1.526	0.99
111_W	252_V	1.520	0.99
374_P	413_L	1.486	0.99
259_V	263_G	1.472	0.99
154_G	161_A	1.465	0.99
221_L	449_F	1.463	0.99
60_A	346_T	1.458	0.99
287_I	297_A	1.452	0.99
286_S	292_R	1.448	0.99
448_Y	452_I	1.443	0.99
177_K	414_E	1.435	0.99
238_A	242_G	1.431	0.99
160_P	225_A	1.430	0.99
164_T	168_I	1.428	0.99
284_G	288_L	1.423	0.99
344_E	350_S	1.419	0.99
35_A	39_V	1.416	0.99
56_T	342_I	1.410	0.99
73_D	77_N	1.405	0.99
129_S	146_L	1.399	0.99
54_A	276_G	1.373	0.99
194_V	198_D	1.367	0.99
221_L	225_A	1.359	0.99
98_S	282_A	1.349	0.99
94_M	301_I	1.335	0.99
191_V	392_G	1.333	0.99
208_I	212_V	1.330	0.99
392_G	413_L	1.327	0.99
368_L	459_V	1.325	0.98
111_W	255_L	1.318	0.98
91_I	272_L	1.312	0.98
116_L	124_L	1.310	0.98
189_S	193_D	1.308	0.98
396_R	400_D	1.308	0.98
442_L	445_L	1.296	0.98
198_D	407_T	1.295	0.98
158_G	161_A	1.292	0.98
421_E	429_G	1.290	0.98
252_V	259_V	1.284	0.98
421_E	427_N	1.284	0.98
165_A	437_L	1.271	0.98
82_G	337_L	1.269	0.98
90_F	327_I	1.269	0.98
461_M	467_K	1.268	0.98
100_V	320_T	1.268	0.98
210_V	454_S	1.260	0.98
70_E	73_D	1.258	0.98
93_Y	322_G	1.251	0.98
374_P	417_G	1.241	0.98
296_E	300_I	1.241	0.98
256_L	285_V	1.239	0.98
184_T	388_I	1.232	0.98
150_L	168_I	1.229	0.98
351_V	355_N	1.228	0.98
367_T	408_S	1.227	0.98
101_D	286_S	1.224	0.97
292_R	300_I	1.223	0.97
241_Q	245_A	1.222	0.97
98_S	283_A	1.217	0.97
217_L	221_L	1.217	0.97
73_D	80_V	1.207	0.97
254_V	285_V	1.204	0.97
412_T	458_V	1.199	0.97
25_L	55_F	1.199	0.97
260_I	263_G	1.198	0.97
441_V	444_Y	1.192	0.97
207_T	454_S	1.191	0.97
285_V	289_I	1.189	0.97
445_L	452_I	1.189	0.97
202_G	407_T	1.188	0.97
360_V	366_A	1.180	0.97
419_V	454_S	1.172	0.97
251_S	261_T	1.169	0.97
203_M	414_E	1.161	0.97
147_G	165_A	1.161	0.97
125_A	167_A	1.160	0.96
217_L	453_L	1.155	0.96
122_V	159_I	1.154	0.96
170_S	218_Y	1.146	0.96
127_L	215_L	1.146	0.96
209_I	212_V	1.144	0.96
254_V	289_I	1.144	0.96
69_D	73_D	1.139	0.96
269_Y	277_A	1.134	0.96
371_A	458_V	1.134	0.96
303_S	324_E	1.133	0.96
74_G	341_G	1.109	0.95
176_D	182_S	1.106	0.95
185_T	414_E	1.104	0.95
363_V	402_Y	1.102	0.95
151_V	165_A	1.096	0.95
79_I	87_F	1.095	0.95
414_E	418_T	1.094	0.95
91_I	279_V	1.091	0.95
366_A	398_L	1.090	0.95
45_A	48_P	1.088	0.95
173_Y	433_M	1.078	0.95
277_A	281_S	1.073	0.95
250_L	253_L	1.067	0.94
130_F	174_M	1.065	0.94
397_D	401_E	1.063	0.94
452_I	456_I	1.060	0.94
464_T	467_K	1.057	0.94
253_L	256_L	1.053	0.94
78_S	341_G	1.053	0.94
87_F	272_L	1.050	0.94
53_I	335_G	1.049	0.94
183_D	188_A	1.048	0.94
411_R	415_E	1.045	0.94
104_T	254_V	1.043	0.94
204_F	208_I	1.041	0.94
151_V	439_V	1.039	0.94
65_G	68_W	1.033	0.93
107_F	254_V	1.032	0.93
357_A	401_E	1.032	0.93
68_W	273_P	1.032	0.93
255_L	261_T	1.030	0.93
239_Q	243_G	1.027	0.93
215_L	219_A	1.018	0.93
398_L	401_E	1.017	0.93
199_H	414_E	1.009	0.93
383_D	387_S	1.007	0.92
253_L	285_V	0.997	0.92
415_E	458_V	0.997	0.92
151_V	155_S	0.996	0.92
364_G	459_V	0.995	0.92
295_A	299_Q	0.995	0.92
177_K	418_T	0.993	0.92
155_S	161_A	0.989	0.92
220_V	223_L	0.985	0.92
22_Q	64_W	0.985	0.92
213_I	217_L	0.983	0.92
24_L	28_A	0.981	0.91
242_G	245_A	0.977	0.91
97_A	101_D	0.973	0.91
260_I	277_A	0.972	0.91
220_V	224_M	0.969	0.91
26_P	30_M	0.969	0.91
257_P	265_A	0.969	0.91
457_L	460_I	0.968	0.91
434_A	440_P	0.966	0.91
154_G	158_G	0.966	0.91
324_E	327_I	0.963	0.91
193_D	396_R	0.960	0.91
86_I	330_I	0.958	0.90
209_I	457_L	0.955	0.90
178_Q	208_I	0.955	0.90
111_W	250_L	0.954	0.90
210_V	214_S	0.953	0.90
258_L	265_A	0.948	0.90
75_I	338_S	0.947	0.90
50_L	94_M	0.946	0.90
205_P	209_I	0.946	0.90
324_E	328_W	0.941	0.90
205_P	466_W	0.931	0.89
251_S	255_L	0.931	0.89
423_M	452_I	0.928	0.89
398_L	402_Y	0.928	0.89
130_F	133_A	0.928	0.89
173_Y	427_N	0.923	0.89
329_V	429_G	0.922	0.89
79_I	334_F	0.921	0.89
214_S	453_L	0.918	0.89
193_D	400_D	0.915	0.88
364_G	368_L	0.913	0.88
73_D	76_S	0.912	0.88
423_M	448_Y	0.908	0.88
360_V	365_G	0.902	0.88
367_T	462_G	0.902	0.88
131_V	259_V	0.895	0.87
419_V	450_V	0.890	0.87
129_S	133_A	0.889	0.87
252_V	257_P	0.887	0.87
69_D	127_L	0.881	0.86
177_K	199_H	0.881	0.86
424_I	427_N	0.881	0.86
450_V	454_S	0.878	0.86
122_V	160_P	0.876	0.86
300_I	303_S	0.873	0.86
130_F	134_T	0.873	0.86
322_G	326_S	0.872	0.86
328_W	331_T	0.869	0.86
254_V	261_T	0.869	0.86
53_I	339_I	0.869	0.86
66_Y	70_E	0.868	0.86
207_T	414_E	0.865	0.85
217_L	454_S	0.865	0.85
199_H	410_S	0.860	0.85
128_L	150_L	0.858	0.85
169_L	448_Y	0.854	0.85
112_G	248_Y	0.853	0.85
384_Q	421_E	0.852	0.85
57_G	71_L	0.852	0.85
174_M	414_E	0.851	0.84
296_E	299_Q	0.850	0.84
368_L	372_L	0.848	0.84
184_T	414_E	0.848	0.84
262_F	266_I	0.848	0.84
384_Q	455_P	0.847	0.84
93_Y	326_S	0.846	0.84
150_L	153_I	0.845	0.84
162_P	443_S	0.841	0.84
360_V	369_V	0.840	0.84
397_D	400_D	0.839	0.84
169_L	381_T	0.837	0.83
76_S	80_V	0.827	0.83
58_V	62_Y	0.825	0.83
29_G	59_I	0.822	0.82
251_S	258_L	0.817	0.82
189_S	196_L	0.815	0.82
362_S	402_Y	0.814	0.82
211_G	215_L	0.814	0.82
440_P	443_S	0.811	0.81
85_A	385_Y	0.805	0.81
116_L	120_V	0.805	0.81
239_Q	242_G	0.804	0.81
237_V	241_Q	0.802	0.81
85_A	141_T	0.802	0.81
264_L	269_Y	0.802	0.81
297_A	300_I	0.802	0.81
446_P	449_F	0.800	0.81
251_S	257_P	0.798	0.80
438_G	441_V	0.797	0.80
206_N	411_R	0.797	0.80
286_S	289_I	0.797	0.80
50_L	335_G	0.795	0.80
453_L	457_L	0.794	0.80
57_G	61_R	0.790	0.80
140_W	432_F	0.790	0.80
102_A	285_V	0.787	0.80
383_D	421_E	0.783	0.79
302_Y	328_W	0.783	0.79
86_I	333_V	0.782	0.79
238_A	241_Q	0.780	0.79
192_S	410_S	0.779	0.79
214_S	217_L	0.779	0.79
178_Q	184_T	0.775	0.78
292_R	296_E	0.774	0.78
202_G	404_L	0.773	0.78
151_V	168_I	0.770	0.78
121_F	157_L	0.769	0.78
287_I	290_Q	0.765	0.78
177_K	185_T	0.764	0.77
78_S	337_L	0.763	0.77
157_L	164_T	0.760	0.77
459_V	463_F	0.755	0.77
86_I	334_F	0.754	0.77
30_M	34_L	0.753	0.76
171_G	175_G	0.750	0.76
461_M	464_T	0.749	0.76
250_L	264_L	0.748	0.76
92_I	275_L	0.747	0.76
26_P	56_T	0.747	0.76
53_I	75_I	0.746	0.76
166_G	448_Y	0.746	0.76
250_L	260_I	0.745	0.76
185_T	188_A	0.745	0.76
265_A	282_A	0.743	0.75
255_L	258_L	0.743	0.75
420_S	451_G	0.742	0.75
256_L	281_S	0.738	0.75
177_K	207_T	0.738	0.75
382_A	421_E	0.733	0.74
126_A	133_A	0.733	0.74
212_V	263_G	0.732	0.74
185_T	418_T	0.729	0.74
343_L	348_V	0.728	0.74
246_G	284_G	0.728	0.74
216_A	219_A	0.727	0.74
399_N	412_T	0.727	0.74
251_S	260_I	0.726	0.74
22_Q	25_L	0.724	0.74
166_G	170_S	0.723	0.73
144_G	148_I	0.722	0.73
383_D	428_S	0.722	0.73
377_I	391_P	0.722	0.73
223_L	226_E	0.722	0.73
133_A	142_T	0.717	0.73
182_S	185_T	0.717	0.73
217_L	220_V	0.715	0.73
249_T	289_I	0.715	0.73
384_Q	429_G	0.714	0.73
251_S	289_I	0.714	0.73
154_G	157_L	0.714	0.73
269_Y	274_S	0.714	0.73
363_V	404_L	0.711	0.72
281_S	285_V	0.710	0.72
141_T	257_P	0.710	0.72
160_P	447_Y	0.709	0.72
276_G	279_V	0.708	0.72
142_T	385_Y	0.706	0.72
60_A	369_V	0.706	0.72
129_S	171_G	0.705	0.72
377_I	381_T	0.703	0.71
94_M	279_V	0.701	0.71
434_A	444_Y	0.700	0.71
457_L	461_M	0.699	0.71
280_F	284_G	0.697	0.71
323_L	331_T	0.692	0.70
120_V	123_P	0.691	0.70
388_I	418_T	0.691	0.70
53_I	57_G	0.690	0.70
137_G	182_S	0.686	0.70
57_G	75_I	0.686	0.70
263_G	266_I	0.684	0.69
383_D	427_N	0.684	0.69
391_P	417_G	0.682	0.69
337_L	392_G	0.679	0.69
388_I	413_L	0.679	0.69
354_H	357_A	0.678	0.69
430_G	444_Y	0.676	0.68
355_N	359_A	0.675	0.68
195_D	201_R	0.674	0.68
381_T	427_N	0.673	0.68
286_S	290_Q	0.672	0.68
138_S	384_Q	0.671	0.68
98_S	297_A	0.670	0.68
341_G	344_E	0.665	0.67
176_D	414_E	0.664	0.67
371_A	462_G	0.663	0.67
123_P	133_A	0.662	0.67
76_S	83_L	0.661	0.67
45_A	49_L	0.661	0.67
179_S	199_H	0.660	0.67
57_G	342_I	0.656	0.66
242_G	246_G	0.656	0.66
165_A	168_I	0.655	0.66
219_A	456_I	0.655	0.66
101_D	104_T	0.654	0.66
53_I	332_I	0.654	0.66
248_Y	290_Q	0.653	0.66
46_Q	331_T	0.652	0.66
151_V	437_L	0.650	0.65
173_Y	422_P	0.650	0.65
378_N	421_E	0.650	0.65
47_M	52_G	0.650	0.65
202_G	461_M	0.649	0.65
387_S	391_P	0.647	0.65
192_S	406_G	0.646	0.65
194_V	405_D	0.645	0.65
214_S	456_I	0.644	0.65
218_Y	221_L	0.642	0.64
174_M	211_G	0.641	0.64
154_G	159_I	0.640	0.64
170_S	448_Y	0.639	0.64
440_P	445_L	0.639	0.64
60_A	264_L	0.638	0.64
97_A	297_A	0.637	0.64
260_I	267_K	0.637	0.64
272_L	275_L	0.636	0.64
376_V	401_E	0.635	0.64
89_L	139_S	0.634	0.63
375_L	379_A	0.634	0.63
139_S	183_D	0.634	0.63
207_T	418_T	0.634	0.63
75_I	87_F	0.633	0.63
76_S	332_I	0.632	0.63
53_I	451_G	0.632	0.63
287_I	294_F	0.631	0.63
332_I	428_S	0.631	0.63
127_L	134_T	0.631	0.63
419_V	455_P	0.629	0.63
399_N	409_L	0.627	0.63
179_S	200_V	0.625	0.62
21_G	24_L	0.625	0.62
179_S	182_S	0.624	0.62
184_T	189_S	0.624	0.62
221_L	447_Y	0.624	0.62
366_A	402_Y	0.623	0.62
139_S	172_V	0.623	0.62
110_Y	212_V	0.623	0.62
149_A	334_F	0.623	0.62
270_P	273_P	0.619	0.62
135_A	262_F	0.619	0.62
291_G	323_L	0.616	0.61
430_G	436_A	0.615	0.61
174_M	182_S	0.614	0.61
88_I	92_I	0.613	0.61
408_S	461_M	0.612	0.61
54_A	58_V	0.611	0.61
357_A	398_L	0.609	0.60
354_H	401_E	0.607	0.60
380_L	422_P	0.606	0.60
382_A	427_N	0.606	0.60
199_H	203_M	0.603	0.60
439_V	443_S	0.602	0.59
403_D	406_G	0.601	0.59
87_F	91_I	0.600	0.59
122_V	154_G	0.600	0.59
25_L	464_T	0.597	0.59
196_L	431_V	0.596	0.59
220_V	239_Q	0.596	0.59
371_A	375_L	0.594	0.58
117_T	124_L	0.594	0.58
32_T	60_A	0.594	0.58
125_A	243_G	0.593	0.58
333_V	386_M	0.592	0.58
61_R	71_L	0.592	0.58
89_L	173_Y	0.588	0.58
389_V	424_I	0.588	0.58
359_A	362_S	0.587	0.58
107_F	251_S	0.587	0.58
142_T	172_V	0.586	0.57
381_T	433_M	0.586	0.57
408_S	464_T	0.586	0.57
141_T	385_Y	0.584	0.57
169_L	433_M	0.584	0.57
327_I	330_I	0.582	0.57
138_S	385_Y	0.582	0.57
371_A	412_T	0.582	0.57
254_V	264_L	0.582	0.57
51_W	298_W	0.581	0.57
49_L	333_V	0.581	0.57
422_P	451_G	0.581	0.57
222_G	226_E	0.579	0.57
32_T	247_T	0.579	0.57
95_L	275_L	0.578	0.56
22_Q	59_I	0.577	0.56
343_L	346_T	0.577	0.56
45_A	331_T	0.575	0.56
181_L	184_T	0.574	0.56
132_V	146_L	0.574	0.56
243_G	246_G	0.572	0.56
430_G	434_A	0.572	0.56
439_V	445_L	0.571	0.56
89_L	330_I	0.571	0.56
31_I	442_L	0.571	0.56
408_S	412_T	0.570	0.55
140_W	421_E	0.568	0.55
139_S	184_T	0.565	0.55
23_A	351_V	0.564	0.55
102_A	404_L	0.563	0.54
48_P	53_I	0.563	0.54
357_A	360_V	0.562	0.54
286_S	297_A	0.562	0.54
320_T	325_G	0.561	0.54
144_G	432_F	0.560	0.54
249_T	253_L	0.560	0.54
185_T	203_M	0.559	0.54
249_T	288_L	0.558	0.54
177_K	183_D	0.558	0.54
146_L	168_I	0.557	0.54
169_L	427_N	0.557	0.54
366_A	370_T	0.556	0.54
210_V	457_L	0.556	0.54
433_M	451_G	0.554	0.53
151_V	436_A	0.552	0.53
106_P	248_Y	0.552	0.53
177_K	203_M	0.551	0.53
363_V	465_G	0.550	0.53
190_G	455_P	0.549	0.53
396_R	406_G	0.549	0.53
163_L	170_S	0.549	0.53
329_V	333_V	0.548	0.53
120_V	124_L	0.547	0.52
86_I	89_L	0.546	0.52
408_S	462_G	0.546	0.52
422_P	433_M	0.545	0.52
51_W	280_F	0.545	0.52
363_V	412_T	0.544	0.52
133_A	137_G	0.544	0.52
373_G	410_S	0.542	0.52
256_L	260_I	0.541	0.52
185_T	199_H	0.541	0.52
360_V	395_F	0.541	0.52
89_L	92_I	0.540	0.51
349_L	377_I	0.539	0.51
378_N	384_Q	0.539	0.51
174_M	178_Q	0.539	0.51
141_T	384_Q	0.538	0.51
137_G	175_G	0.538	0.51
177_K	182_S	0.538	0.51
218_Y	222_G	0.538	0.51
49_L	336_A	0.536	0.51
208_I	228_G	0.536	0.51
220_V	247_T	0.536	0.51
66_Y	345_A	0.536	0.51
165_A	439_V	0.535	0.51
330_I	352_I	0.534	0.51
129_S	168_I	0.532	0.50
367_T	370_T	0.532	0.50
295_A	449_F	0.532	0.50
354_H	442_L	0.531	0.50
126_A	130_F	0.531	0.50
137_G	179_S	0.531	0.50
245_A	280_F	0.531	0.50
174_M	177_K	0.530	0.50
67_T	73_D	0.530	0.50
79_I	83_L	0.530	0.50
47_M	390_I	0.529	0.50
30_M	56_T	0.529	0.50
56_T	59_I	0.529	0.50
206_N	458_V	0.528	0.50
256_L	300_I	0.528	0.50
177_K	184_T	0.528	0.50
244_L	278_G	0.527	0.50
49_L	59_I	0.525	0.50
69_D	72_F	0.525	0.50
202_G	411_R	0.525	0.50
141_T	429_G	0.525	0.50
137_G	176_D	0.525	0.50
173_Y	420_S	0.525	0.50
185_T	200_V	0.524	0.49
384_Q	450_V	0.524	0.49
105_I	336_A	0.524	0.49
165_A	444_Y	0.524	0.49
37_G	40_L	0.524	0.49
199_H	418_T	0.523	0.49
62_Y	65_G	0.523	0.49
174_M	185_T	0.522	0.49
416_T	458_V	0.522	0.49
377_I	417_G	0.520	0.49
421_E	428_S	0.520	0.49
256_L	354_H	0.520	0.49
228_G	260_I	0.520	0.49
202_G	467_K	0.519	0.49
337_L	378_N	0.519	0.49
238_A	284_G	0.519	0.49
239_Q	263_G	0.518	0.49
156_G	260_I	0.517	0.48
196_L	206_N	0.516	0.48
140_W	428_S	0.516	0.48
250_L	257_P	0.515	0.48
211_G	450_V	0.515	0.48
35_A	116_L	0.514	0.48
461_M	466_W	0.514	0.48
248_Y	438_G	0.512	0.48
347_G	350_S	0.512	0.48
430_G	445_L	0.511	0.48
337_L	340_G	0.510	0.48
48_P	333_V	0.510	0.48
331_T	334_F	0.508	0.47
253_L	264_L	0.508	0.47
69_D	354_H	0.508	0.47
157_L	222_G	0.508	0.47
110_Y	114_E	0.507	0.47
280_F	403_D	0.507	0.47
184_T	418_T	0.507	0.47
193_D	266_I	0.506	0.47
162_P	442_L	0.505	0.47
380_L	398_L	0.505	0.47
54_A	73_D	0.503	0.47
46_Q	340_G	0.503	0.47
147_G	336_A	0.503	0.47
216_A	363_V	0.502	0.47
187_L	388_I	0.501	0.46
282_A	286_S	0.500	0.46
121_F	165_A	0.500	0.46

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4f35D	2	0.8247	100	0.777	Contact Map
4r1iA	2	0.9052	99.9	0.798	Contact Map
4r0cA	3	0.8825	99.8	0.837	Contact Map
4pd6A	3	0.4309	76	0.964	Contact Map
3qe7A	2	0.7216	75.1	0.964	Contact Map
3zuxA	1	0.6082	50.2	0.97	Contact Map
2kncA	1	0.1113	20.9	0.975	Contact Map
4ikvA	1	0.8268	16.2	0.976	Contact Map
2nwlA	3	0.3423	13.7	0.977	Contact Map
3o7qA	1	0.3753	11.5	0.978	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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