GREMLIN Database
SPH1 - Smc-like protein Sph1
UniProt: Q9HHM7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 629 (574)
Sequences: 5324 (5123)
Seq/√Len: 213.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
5_D16_E3.4451.00
3_N16_E3.3621.00
67_T80_T2.8741.00
222_R226_R2.5991.00
5_D67_T2.5711.00
44_A68_L2.4651.00
234_V238_K2.4091.00
208_A212_E2.3911.00
422_E425_T2.3431.00
541_L571_L2.3001.00
31_F538_E2.2971.00
541_L575_H2.2971.00
408_E411_A2.2841.00
343_R347_T2.2501.00
326_T330_N2.2281.00
265_E269_R2.1711.00
243_D247_A2.1691.00
397_E401_E2.1671.00
448_E452_Q2.1481.00
496_R585_N2.1461.00
227_L231_E2.1181.00
255_D258_T2.0891.00
309_D313_C2.0831.00
269_R272_E2.0821.00
229_R233_Q2.0711.00
536_E567_G2.0491.00
231_E235_D2.0421.00
3_N69_E2.0391.00
233_Q236_R2.0311.00
450_E453_K2.0201.00
396_E399_Q2.0131.00
244_K248_L2.0001.00
394_T397_E1.9961.00
279_L283_L1.9851.00
335_R338_S1.9831.00
385_Q389_R1.9781.00
331_E335_R1.9721.00
67_T78_S1.9581.00
271_D274_A1.9541.00
218_S222_R1.9501.00
9_I43_T1.9491.00
325_V328_R1.9481.00
190_N194_D1.9341.00
457_R461_L1.9301.00
215_A219_D1.9131.00
272_E276_K1.9111.00
270_I274_A1.9071.00
383_E387_E1.8871.00
217_Q221_E1.8871.00
374_I378_R1.8821.00
375_K378_R1.8691.00
345_T349_E1.8541.00
194_D197_E1.8511.00
185_E188_D1.8451.00
258_T262_D1.8381.00
7_T65_K1.8321.00
308_G312_S1.8131.00
10_G36_S1.8071.00
187_R190_N1.8021.00
238_K242_D1.8021.00
43_T66_V1.7971.00
464_K468_L1.7961.00
328_R331_E1.7931.00
410_E413_E1.7901.00
206_Q210_R1.7751.00
567_G592_T1.7531.00
373_E376_R1.7511.00
475_R479_Y1.7301.00
342_Q345_T1.7291.00
324_A328_R1.7251.00
472_R476_K1.7171.00
425_T429_K1.7151.00
334_D338_S1.7151.00
262_D265_E1.7141.00
344_A347_T1.7081.00
310_T314_F1.7021.00
384_D387_E1.6941.00
367_K371_E1.6851.00
6_V37_F1.6751.00
293_E297_D1.6751.00
366_Q369_E1.6741.00
378_R382_Q1.6691.00
336_Q340_R1.6651.00
223_E226_R1.6641.00
489_A492_D1.6591.00
400_A404_Q1.6481.00
278_D281_D1.6461.00
430_I434_E1.6411.00
205_D208_A1.6401.00
287_T291_I1.6391.00
292_D295_E1.6391.00
286_S290_I1.6261.00
230_L234_V1.6251.00
159_E163_A1.6231.00
474_R478_K1.6141.00
318_A321_T1.6081.00
246_A250_S1.6071.00
212_E216_K1.6031.00
395_I399_Q1.5991.00
225_A228_E1.5991.00
57_L64_G1.5981.00
445_E448_E1.5941.00
327_E331_E1.5861.00
268_T272_E1.5841.00
247_A250_S1.5821.00
465_R469_E1.5801.00
376_R380_D1.5791.00
399_Q403_E1.5751.00
568_I595_Y1.5741.00
313_C317_G1.5721.00
472_R475_R1.5641.00
193_R197_E1.5621.00
393_A396_E1.5621.00
317_G321_T1.5611.00
440_A444_L1.5601.00
17_A37_F1.5551.00
141_T147_R1.5531.00
341_E345_T1.5431.00
266_K270_I1.5351.00
314_F317_G1.5311.00
266_K269_R1.5271.00
280_L284_H1.5251.00
380_D383_E1.5221.00
392_E396_E1.5191.00
540_E570_Q1.5171.00
544_I547_A1.5121.00
264_A267_Q1.5111.00
318_A322_A1.5011.00
291_I295_E1.5001.00
216_K220_L1.4921.00
493_I497_F1.4901.00
168_A172_L1.4891.00
168_A171_D1.4791.00
463_T467_E1.4791.00
316_C319_E1.4771.00
434_E438_D1.4751.00
174_A178_K1.4741.00
277_I281_D1.4711.00
271_D275_V1.4711.00
461_L464_K1.4701.00
337_E340_R1.4671.00
357_T361_E1.4661.00
290_I294_G1.4621.00
225_A229_R1.4551.00
4_V19_L1.4471.00
322_A326_T1.4451.00
31_F575_H1.4431.00
290_I293_E1.4421.00
332_I336_Q1.4411.00
211_D215_A1.4381.00
69_E78_S1.4311.00
424_K428_Q1.4301.00
347_T351_T1.4291.00
289_A293_E1.4241.00
432_S436_K1.4091.00
162_V166_E1.4071.00
455_N459_E1.4041.00
283_L286_S1.4041.00
369_E373_E1.4011.00
6_V40_A1.4001.00
443_E446_R1.3961.00
387_E391_I1.3961.00
276_K279_L1.3911.00
396_E400_A1.3911.00
403_E406_E1.3861.00
147_R150_A1.3861.00
437_L441_Q1.3821.00
382_Q385_Q1.3731.00
283_L287_T1.3711.00
171_D174_A1.3621.00
458_Q462_E1.3541.00
198_R202_E1.3481.00
449_A453_K1.3461.00
381_I385_Q1.3451.00
547_A569_G1.3411.00
285_R289_A1.3401.00
210_R214_T1.3341.00
325_V329_L1.3321.00
312_S316_C1.3241.00
181_R185_E1.3191.00
342_Q346_L1.3191.00
328_R332_I1.3151.00
284_H288_K1.3131.00
426_I430_I1.3101.00
288_K292_D1.3061.00
372_D376_R1.3031.00
354_Q358_R1.3021.00
435_T439_R1.2971.00
8_C14_S1.2961.00
330_N333_S1.2961.00
226_R230_L1.2941.00
230_L233_Q1.2911.00
543_G575_H1.2891.00
419_H423_L1.2851.00
224_E228_E1.2771.00
10_G25_I1.2721.00
295_E299_I1.2711.00
540_E569_G1.2681.00
444_L448_E1.2681.00
419_H422_E1.2651.00
564_L590_L1.2621.00
339_L343_R1.2611.00
242_D245_E1.2571.00
339_L342_Q1.2551.00
223_E227_L1.2541.00
436_K439_R1.2521.00
267_Q270_I1.2511.00
438_D441_Q1.2511.00
28_A32_Q1.2511.00
540_E547_A1.2501.00
540_E594_A1.2461.00
320_T324_A1.2461.00
309_D312_S1.2461.00
567_G594_A1.2441.00
219_D222_R1.2431.00
221_E224_E1.2411.00
182_L186_L1.2401.00
446_R450_E1.2391.00
279_L282_D1.2381.00
459_E463_T1.2351.00
538_E567_G1.2321.00
569_G595_Y1.2301.00
373_E377_L1.2301.00
562_C588_E1.2291.00
358_R362_S1.2271.00
169_S173_P1.2271.00
352_Q356_R1.2261.00
259_A263_I1.2231.00
436_K440_A1.2231.00
189_L192_T1.2201.00
236_R240_Q1.2201.00
482_L485_Q1.2151.00
154_E157_E1.2141.00
344_A348_E1.2051.00
428_Q431_G1.2041.00
346_L349_E1.2041.00
544_I579_M1.2031.00
540_E568_I1.2021.00
142_E146_L1.2011.00
296_I300_T1.2001.00
560_V569_G1.2001.00
407_A411_A1.1981.00
370_L374_I1.1931.00
409_Y413_E1.1931.00
536_E570_Q1.1921.00
351_T354_Q1.1861.00
543_G571_L1.1821.00
434_E437_L1.1811.00
179_V183_Q1.1811.00
144_I147_R1.1801.00
423_L427_Q1.1741.00
156_K160_D1.1741.00
189_L193_R1.1731.00
418_S422_E1.1721.00
330_N334_D1.1711.00
267_Q271_D1.1661.00
449_A452_Q1.1651.00
214_T218_S1.1651.00
30_N575_H1.1631.00
10_G43_T1.1631.00
377_L381_I1.1611.00
476_K479_Y1.1581.00
259_A262_D1.1571.00
547_A575_H1.1541.00
241_L245_E1.1521.00
286_S289_A1.1501.00
547_A594_A1.1501.00
384_D388_V1.1441.00
40_A44_A1.1381.00
540_E575_H1.1351.00
174_A177_Q1.1321.00
183_Q187_R1.1281.00
194_D198_R1.1271.00
569_G580_I1.1271.00
201_D204_T1.1231.00
375_K379_V1.1221.00
261_A265_E1.1161.00
44_A66_V1.1151.00
41_I68_L1.1121.00
197_E201_D1.1111.00
237_R241_L1.1081.00
565_L568_I1.1031.00
540_E567_G1.1021.00
145_D148_I1.0981.00
3_N18_T1.0961.00
429_K432_S1.0941.00
178_K181_R1.0931.00
461_L465_R1.0921.00
247_A251_L1.0901.00
348_E352_Q1.0901.00
12_I37_F1.0901.00
56_P59_E1.0881.00
289_A292_D1.0851.00
11_G36_S1.0841.00
212_E215_A1.0831.00
455_N458_Q1.0821.00
433_T437_L1.0801.00
411_A415_A1.0771.00
170_A173_P1.0761.00
548_L583_L1.0751.00
486_F490_M1.0741.00
273_L277_I1.0741.00
445_E449_A1.0721.00
538_E541_L1.0701.00
207_R210_R1.0691.00
389_R392_E1.0651.00
335_R339_L1.0601.00
454_R458_Q1.0581.00
120_R124_R1.0581.00
19_L24_N1.0581.00
92_R97_Y1.0581.00
447_I451_L1.0571.00
464_K472_R1.0551.00
569_G579_M1.0511.00
239_A242_D1.0481.00
182_L185_E1.0481.00
40_A66_V1.0461.00
306_L310_T1.0441.00
468_L472_R1.0411.00
121_A126_E1.0411.00
167_A171_D1.0401.00
379_V383_E1.0371.00
314_F318_A1.0371.00
240_Q244_K1.0361.00
429_K433_T1.0351.00
237_R240_Q1.0351.00
570_Q594_A1.0351.00
323_E326_T1.0301.00
431_G434_E1.0281.00
500_G504_A1.0251.00
538_E592_T1.0241.00
484_N498_A1.0241.00
262_D266_K1.0231.00
31_F541_L1.0211.00
481_E485_Q1.0191.00
122_A125_E1.0161.00
199_K202_E1.0151.00
427_Q431_G1.0151.00
401_E405_R1.0131.00
305_T308_G1.0111.00
358_R361_E1.0111.00
567_G571_L1.0061.00
9_I39_A1.0021.00
282_D286_S1.0011.00
311_F315_V0.9981.00
487_D490_M0.9981.00
442_A445_E0.9981.00
296_I299_I0.9931.00
576_I595_Y0.9861.00
575_H588_E0.9861.00
122_A126_E0.9831.00
543_G554_F0.9821.00
255_D259_A0.9811.00
489_A493_I0.9801.00
403_E407_A0.9801.00
240_Q243_D0.9791.00
417_E420_S0.9791.00
540_E561_P0.9791.00
540_E571_L0.9761.00
377_L380_D0.9751.00
180_T184_G0.9741.00
175_A179_V0.9711.00
372_D375_K0.9691.00
406_E410_E0.9691.00
10_G39_A0.9661.00
94_G99_T0.9661.00
160_D164_A0.9651.00
388_V392_E0.9641.00
444_L447_I0.9631.00
538_E547_A0.9591.00
242_D246_A0.9581.00
518_F524_R0.9581.00
456_D460_Q0.9571.00
307_S310_T0.9561.00
313_C316_C0.9531.00
221_E225_A0.9511.00
155_I159_E0.9481.00
323_E327_E0.9471.00
340_R343_R0.9451.00
166_E169_S0.9431.00
454_R457_R0.9431.00
501_F504_A0.9410.99
492_D496_R0.9390.99
398_L402_I0.9380.99
249_E252_D0.9370.99
570_Q595_Y0.9350.99
232_N236_R0.9350.99
235_D238_K0.9240.99
154_E158_L0.9240.99
424_K427_Q0.9240.99
65_K82_A0.9200.99
539_R570_Q0.9200.99
368_A372_D0.9170.99
371_E375_K0.9170.99
196_L199_K0.9160.99
540_E543_G0.9160.99
186_L190_N0.9150.99
437_L440_A0.9150.99
337_E341_E0.9140.99
246_A249_E0.9130.99
421_A425_T0.9120.99
393_A397_E0.9110.99
278_D282_D0.9090.99
228_E231_E0.9070.99
10_G46_G0.8970.99
264_A268_T0.8950.99
383_E386_H0.8950.99
404_Q407_A0.8920.99
468_L475_R0.8910.99
442_A446_R0.8910.99
426_I429_K0.8910.99
10_G47_T0.8900.99
338_S342_Q0.8890.99
93_S97_Y0.8850.99
386_H390_S0.8850.99
23_P43_T0.8810.99
113_L118_P0.8810.99
460_Q463_T0.8790.99
131_L134_L0.8790.99
228_E232_N0.8790.99
467_E475_R0.8790.99
561_P587_A0.8780.99
410_E414_K0.8750.99
488_A492_D0.8710.99
333_S337_E0.8700.99
428_Q432_S0.8700.99
7_T14_S0.8700.99
376_R379_V0.8690.99
143_N147_R0.8690.99
408_E412_A0.8680.99
439_R443_E0.8680.99
151_L154_E0.8650.99
435_T438_D0.8640.99
580_I595_Y0.8640.99
12_I15_G0.8570.99
457_R472_R0.8560.99
220_L227_L0.8540.99
407_A410_E0.8530.99
475_R480_N0.8510.99
31_F537_G0.8490.99
272_E275_V0.8470.99
310_T313_C0.8450.99
144_I148_I0.8450.99
207_R211_D0.8440.99
269_R273_L0.8430.99
563_I587_A0.8420.99
45_I68_L0.8400.99
521_N528_T0.8400.99
49_G52_T0.8330.99
356_R359_E0.8320.99
538_E575_H0.8320.99
441_Q445_E0.8320.99
340_R344_A0.8310.99
89_A94_G0.8260.99
571_L594_A0.8260.99
205_D209_L0.8240.99
263_I267_Q0.8230.99
10_G42_Q0.8210.99
547_A561_P0.8210.99
305_T309_D0.8180.99
464_K467_E0.8180.99
571_L575_H0.8170.99
192_T195_E0.8160.99
483_V487_D0.8150.99
414_K417_E0.8150.99
413_E417_E0.8150.99
157_E160_D0.8140.99
21_P24_N0.8120.99
9_I64_G0.8110.98
70_T77_V0.8090.98
273_L276_K0.8070.98
568_I587_A0.8070.98
20_R24_N0.8060.98
256_S260_E0.8040.98
346_L350_V0.8030.98
166_E170_A0.7960.98
470_T474_R0.7960.98
116_D119_I0.7940.98
130_R133_E0.7930.98
387_E390_S0.7910.98
547_A570_Q0.7900.98
355_Q358_R0.7850.98
213_L217_Q0.7840.98
177_Q181_R0.7840.98
89_A92_R0.7820.98
25_I593_T0.7820.98
315_V318_A0.7800.98
471_L475_R0.7790.98
115_E118_P0.7790.98
321_T324_A0.7790.98
359_E363_K0.7780.98
70_T79_L0.7770.98
243_D246_A0.7770.98
287_T290_I0.7740.98
209_L213_L0.7720.98
555_S558_D0.7720.98
577_R581_E0.7710.98
65_K80_T0.7710.98
431_G435_T0.7700.98
123_V126_E0.7670.98
534_L542_V0.7670.98
443_E447_I0.7660.98
412_A416_G0.7650.98
265_E268_T0.7620.98
540_E563_I0.7620.98
167_A170_A0.7600.98
69_E76_T0.7570.98
444_L451_L0.7570.98
257_P260_E0.7570.98
404_Q408_E0.7560.98
394_T398_L0.7540.98
245_E252_D0.7510.98
446_R449_A0.7510.98
460_Q475_R0.7510.98
540_E579_M0.7510.98
294_G298_L0.7470.97
544_I568_I0.7460.97
136_K139_L0.7440.97
538_E569_G0.7420.97
239_A243_D0.7420.97
63_D82_A0.7420.97
536_E592_T0.7410.97
39_A51_L0.7400.97
345_T348_E0.7390.97
562_C575_H0.7390.97
137_K140_E0.7380.97
422_E426_I0.7380.97
483_V490_M0.7380.97
371_E374_I0.7380.97
233_Q237_R0.7370.97
534_L576_I0.7340.97
218_S221_E0.7340.97
145_D150_A0.7340.97
6_V12_I0.7330.97
544_I548_L0.7330.97
416_G420_S0.7330.97
176_Q179_V0.7320.97
89_A96_P0.7300.97
319_E323_E0.7300.97
561_P582_Y0.7300.97
554_F561_P0.7250.97
425_T428_Q0.7240.97
433_T436_K0.7230.97
118_P121_A0.7220.97
25_I39_A0.7220.97
93_S96_P0.7200.97
468_L474_R0.7190.97
420_S424_K0.7190.97
538_E571_L0.7180.97
543_G546_T0.7180.97
31_F547_A0.7170.97
368_A371_E0.7160.97
226_R229_R0.7140.97
471_L478_K0.7140.97
518_F522_L0.7130.97
569_G589_I0.7130.97
140_E147_R0.7120.97
406_E409_Y0.7100.97
360_I363_K0.7100.97
334_D337_E0.7070.96
176_Q180_T0.7070.96
236_R239_A0.7060.96
282_D285_R0.7050.96
185_E189_L0.7040.96
142_E147_R0.7020.96
536_E540_E0.7010.96
524_R569_G0.7000.96
24_N43_T0.6990.96
541_L547_A0.6990.96
32_Q567_G0.6970.96
46_G49_G0.6960.96
349_E353_M0.6940.96
217_Q220_L0.6930.96
554_F558_D0.6930.96
359_E362_S0.6930.96
294_G297_D0.6880.96
402_I406_E0.6870.96
332_I335_R0.6860.96
529_T533_T0.6850.96
548_L582_Y0.6850.96
55_H58_M0.6840.96
325_V332_I0.6800.96
565_L589_I0.6790.96
257_P261_A0.6790.96
471_L479_Y0.6780.95
251_L255_D0.6770.95
317_G320_T0.6760.95
10_G569_G0.6740.95
306_L309_D0.6740.95
275_V279_L0.6730.95
214_T217_Q0.6720.95
491_A495_G0.6720.95
120_R125_E0.6710.95
540_E592_T0.6700.95
268_T271_D0.6700.95
561_P588_E0.6700.95
152_Q155_I0.6700.95
490_M498_A0.6690.95
5_D14_S0.6670.95
245_E249_E0.6670.95
349_E352_Q0.6660.95
539_R543_G0.6650.95
502_D506_L0.6650.95
590_L595_Y0.6650.95
164_A167_A0.6630.95
161_E164_A0.6630.95
158_L161_E0.6610.95
494_I542_V0.6600.95
91_S96_P0.6600.95
570_Q586_T0.6600.95
569_G594_A0.6590.95
244_K247_A0.6590.95
487_D491_A0.6580.95
476_K480_N0.6570.95
55_H59_E0.6570.95
531_L539_R0.6540.95
184_G188_D0.6530.94
366_Q370_L0.6510.94
555_S563_I0.6510.94
490_M493_I0.6500.94
10_G35_S0.6490.94
582_Y586_T0.6490.94
216_K219_D0.6480.94
547_A567_G0.6480.94
159_E162_V0.6480.94
113_L116_D0.6480.94
9_I30_N0.6460.94
498_A538_E0.6460.94
576_I584_E0.6460.94
137_K145_D0.6450.94
490_M494_I0.6450.94
292_D296_I0.6450.94
546_T569_G0.6450.94
158_L162_V0.6450.94
401_E404_Q0.6440.94
571_L579_M0.6440.94
544_I554_F0.6440.94
88_P97_Y0.6420.94
153_R157_E0.6420.94
275_V278_D0.6410.94
8_C27_Q0.6400.94
570_Q587_A0.6400.94
539_R592_T0.6390.94
534_L570_Q0.6390.94
224_E227_L0.6380.94
4_V68_L0.6370.94
260_E264_A0.6370.94
563_I594_A0.6360.94
135_L138_P0.6360.94
353_M356_R0.6340.94
11_G24_N0.6330.94
538_E594_A0.6300.93
490_M497_F0.6300.93
497_F545_V0.6300.93
336_Q343_R0.6300.93
574_E578_H0.6300.93
87_E94_G0.6280.93
544_I571_L0.6280.93
462_E466_D0.6280.93
94_G97_Y0.6280.93
141_T144_I0.6270.93
219_D223_E0.6260.93
561_P568_I0.6260.93
579_M595_Y0.6260.93
554_F562_C0.6250.93
49_G53_E0.6250.93
365_Q368_A0.6250.93
365_Q369_E0.6240.93
168_A174_A0.6240.93
521_N524_R0.6240.93
115_E119_I0.6220.93
273_L280_L0.6210.93
280_L283_L0.6200.93
491_A494_I0.6190.93
547_A555_S0.6190.93
555_S595_Y0.6190.93
134_L141_T0.6180.93
541_L582_Y0.6180.93
520_I524_R0.6180.93
536_E568_I0.6170.93
484_N487_D0.6160.93
40_A45_I0.6150.93
483_V494_I0.6140.92
541_L588_E0.6130.92
297_D301_D0.6130.92
405_R409_Y0.6130.92
540_E595_Y0.6110.92
36_S40_A0.6100.92
180_T183_Q0.6100.92
515_T520_I0.6100.92
468_L471_L0.6100.92
126_E131_L0.6090.92
520_I523_A0.6090.92
397_E400_A0.6090.92
474_R477_Q0.6080.92
161_E165_A0.6080.92
137_K141_T0.6070.92
541_L592_T0.6070.92
529_T568_I0.6060.92
536_E594_A0.6060.92
464_K475_R0.6050.92
540_E576_I0.6040.92
560_V568_I0.6030.92
315_V319_E0.6010.92
461_L472_R0.6000.92
31_F43_T0.5990.92
398_L401_E0.5990.92
543_G592_T0.5990.92
206_Q209_L0.5990.92
120_R123_V0.5980.91
258_T261_A0.5980.91
141_T145_D0.5980.91
561_P575_H0.5980.91
249_E254_P0.5970.91
405_R408_E0.5970.91
140_E145_D0.5970.91
173_P176_Q0.5960.91
46_G77_V0.5950.91
423_L426_I0.5950.91
482_L494_I0.5940.91
540_E545_V0.5930.91
348_E351_T0.5910.91
415_A418_S0.5910.91
489_A556_V0.5900.91
386_H389_R0.5890.91
567_G570_Q0.5890.91
464_K471_L0.5880.91
283_L290_I0.5880.91
523_A528_T0.5870.91
229_R232_N0.5870.91
35_S51_L0.5860.91
570_Q576_I0.5860.91
354_Q357_T0.5860.91
575_H587_A0.5840.91
43_T56_P0.5840.91
472_R479_Y0.5840.91
291_I294_G0.5840.91
150_A154_E0.5820.90
109_L112_V0.5820.90
432_S435_T0.5820.90
391_I395_I0.5820.90
86_D89_A0.5810.90
134_L139_L0.5810.90
191_E195_E0.5800.90
576_I580_I0.5800.90
170_A174_A0.5790.90
248_L252_D0.5780.90
571_L576_I0.5780.90
569_G592_T0.5760.90
327_E330_N0.5760.90
485_Q489_A0.5760.90
573_A595_Y0.5750.90
329_L333_S0.5750.90
160_D163_A0.5750.90
539_R547_A0.5740.90
311_F314_F0.5740.90
39_A536_E0.5730.90
419_H426_I0.5730.90
8_C15_G0.5720.90
544_I587_A0.5720.90
11_G38_L0.5720.90
546_T568_I0.5710.90
576_I594_A0.5700.89
26_V592_T0.5690.89
563_I579_M0.5680.89
541_L563_I0.5670.89
563_I569_G0.5660.89
518_F523_A0.5640.89
234_V241_L0.5640.89
541_L576_I0.5630.89
154_E161_E0.5630.89
341_E344_A0.5620.89
125_E138_P0.5620.89
547_A592_T0.5610.89
568_I594_A0.5610.89
490_M502_D0.5600.89
254_P257_P0.5590.89
382_Q386_H0.5570.88
87_E96_P0.5570.88
579_M586_T0.5570.88
24_N68_L0.5560.88
232_N235_D0.5550.88
460_Q464_K0.5550.88
77_V84_D0.5510.88
570_Q590_L0.5510.88
10_G66_V0.5500.88
38_L41_I0.5490.88
541_L593_T0.5490.88
457_R460_Q0.5480.88
31_F543_G0.5470.87
120_R131_L0.5470.87
544_I555_S0.5470.87
461_L479_Y0.5460.87
285_R288_K0.5450.87
587_A595_Y0.5430.87
188_D192_T0.5410.87
538_E593_T0.5400.87
24_N56_P0.5400.87
193_R196_L0.5400.87
189_L196_L0.5390.87
110_F118_P0.5390.87
563_I568_I0.5380.87
570_Q582_Y0.5370.87
9_I40_A0.5370.87
546_T570_Q0.5350.86
536_E595_Y0.5350.86
563_I589_I0.5330.86
548_L570_Q0.5330.86
43_T565_L0.5330.86
540_E589_I0.5330.86
494_I497_F0.5330.86
547_A564_L0.5310.86
462_E465_R0.5310.86
485_Q488_A0.5300.86
567_G575_H0.5290.86
11_G27_Q0.5270.85
540_E583_L0.5270.85
466_D470_T0.5260.85
493_I496_R0.5240.85
11_G31_F0.5230.85
518_F521_N0.5230.85
527_H530_D0.5230.85
177_Q180_T0.5220.85
149_E153_R0.5200.85
543_G569_G0.5180.85
570_Q592_T0.5170.84
47_T81_R0.5170.84
137_K144_I0.5160.84
9_I587_A0.5160.84
524_R529_T0.5150.84
517_G524_R0.5150.84
575_H579_M0.5140.84
138_P145_D0.5120.84
114_G117_N0.5120.84
91_S94_G0.5120.84
554_F576_I0.5120.84
490_M545_V0.5120.84
5_D69_E0.5120.84
555_S587_A0.5110.84
561_P589_I0.5110.84
121_A124_R0.5100.84
24_N30_N0.5090.83
198_R201_D0.5090.83
568_I588_E0.5080.83
494_I545_V0.5080.83
542_V562_C0.5080.83
36_S44_A0.5070.83
114_G118_P0.5070.83
276_K280_L0.5060.83
4_V41_I0.5060.83
533_T548_L0.5060.83
561_P592_T0.5060.83
213_L216_K0.5050.83
463_T466_D0.5050.83
86_D90_I0.5050.83
538_E568_I0.5030.83
370_L373_E0.5030.83
498_A579_M0.5030.83
565_L587_A0.5030.83
457_R471_L0.5030.83
540_E562_C0.5000.82
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ux3A 1 0.6582 100 0.524 Contact Map
4ad8A 1 0.6566 100 0.551 Contact Map
3zgxA 2 0.5215 100 0.563 Contact Map
3auyA 2 0.5596 100 0.563 Contact Map
1w1wA 2 0.4944 100 0.609 Contact Map
3qf7A 2 0.5342 100 0.632 Contact Map
4abyA 1 0.5215 100 0.643 Contact Map
3qktA 2 0.5072 100 0.645 Contact Map
4i99A 2 0.4722 100 0.652 Contact Map
1e69A 1 0.3959 99.9 0.727 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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