GREMLIN Database
Q9HHJ8 - DNA polymerase B2
UniProt: Q9HHJ8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 722 (651)
Sequences: 2023 (1213)
Seq/√Len: 47.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
332_E477_R6.7511.00
570_D608_R6.2711.00
598_E603_N4.9491.00
85_V94_L4.7751.00
494_V497_E4.6221.00
373_V376_L4.3651.00
594_R598_E4.2881.00
69_R300_G4.2331.00
599_L609_L4.1281.00
34_R125_E4.0211.00
167_S200_M3.7911.00
178_L186_L3.5971.00
166_S169_D3.5531.00
468_K472_E3.3181.00
659_S662_R3.1291.00
571_V595_A3.0571.00
232_G235_G3.0321.00
141_L174_V3.0251.00
173_A176_G3.0111.00
190_T193_I2.9601.00
68_A77_E2.9491.00
372_D375_G2.9481.00
469_Q473_A2.8721.00
168_T172_A2.8531.00
574_D578_R2.8491.00
153_Y197_L2.8451.00
273_K294_C2.8291.00
662_R665_L2.7741.00
590_G594_R2.7741.00
500_E504_T2.7151.00
408_E418_R2.7121.00
193_I250_D2.6931.00
68_A79_A2.6351.00
299_R389_D2.6341.00
374_P377_G2.6331.00
392_Q396_D2.6301.00
651_V673_Y2.6101.00
523_Y553_K2.5431.00
182_D213_R2.4961.00
188_C191_S2.4751.00
665_L668_E2.4311.00
652_V677_Y2.4221.00
404_A422_L2.4011.00
156_L174_V2.3851.00
504_T508_E2.3781.00
144_P193_I2.3731.00
474_G508_E2.3371.00
289_T446_K2.3271.00
295_E298_D2.3151.00
437_F453_H2.2881.00
585_P588_V2.2771.00
136_L185_V2.2741.00
230_S233_R2.2531.00
573_R577_D2.2421.00
153_Y157_S2.1891.00
497_E500_E2.1881.00
379_S382_D2.1661.00
676_S679_E2.1631.00
118_R125_E2.1601.00
506_A510_T2.1391.00
295_E393_P2.1361.00
539_L551_D2.1201.00
394_I429_L2.1071.00
341_E487_W2.1011.00
111_C114_V2.0961.00
356_N385_G2.0901.00
630_A634_R2.0881.00
416_E419_L2.0761.00
665_L669_A2.0471.00
591_R595_A2.0451.00
536_A557_I2.0441.00
477_R489_T2.0411.00
508_E511_E1.9950.99
507_T511_E1.9940.99
144_P250_D1.9780.99
372_D376_L1.9550.99
48_L52_Q1.9350.99
532_R535_D1.9310.99
531_Q535_D1.9210.99
560_R628_N1.9100.99
65_E82_A1.8770.99
600_Q676_S1.8570.99
199_E202_T1.8470.99
142_S246_R1.8440.99
50_T54_V1.8380.99
597_D601_A1.8360.99
51_L55_Y1.8300.99
185_V262_L1.8280.99
577_D581_A1.8220.99
400_E403_A1.8220.99
612_R647_D1.8110.99
584_S587_A1.8090.99
408_E415_D1.7970.99
33_P113_N1.7860.99
53_S57_Q1.7480.98
356_N361_V1.7230.98
127_G298_D1.7160.98
193_I246_R1.7160.98
521_A553_K1.7160.98
666_A669_A1.7120.98
558_E688_S1.7100.98
142_S193_I1.7030.98
385_G388_V1.6990.98
47_D50_T1.6930.98
618_P621_G1.6920.98
250_D457_N1.6920.98
291_I432_I1.6850.98
37_V83_V1.6810.98
70_R77_E1.6780.98
268_L428_A1.6770.98
598_E604_V1.6690.98
28_R122_Y1.6640.98
138_T185_V1.6620.98
387_L440_Q1.6500.98
267_D425_R1.6360.98
117_S120_F1.6300.98
652_V663_V1.6300.98
156_L159_A1.6250.98
88_I118_R1.6240.98
139_L178_L1.6040.97
153_Y156_L1.6040.97
355_R463_I1.6030.97
403_A406_R1.5990.97
481_G485_S1.5970.97
482_I532_R1.5960.97
229_S235_G1.5900.97
125_E300_G1.5870.97
696_D699_N1.5830.97
373_V377_G1.5830.97
144_P246_R1.5760.97
157_S251_E1.5750.97
472_E477_R1.5570.97
64_T81_L1.5550.97
325_G457_N1.5510.97
453_H460_A1.5510.97
47_D52_Q1.5470.97
633_K636_R1.5380.97
376_L380_I1.5380.97
509_I517_L1.5340.96
88_I91_V1.5290.96
49_T52_Q1.5100.96
325_G328_I1.5090.96
32_T63_A1.5050.96
62_V86_A1.5040.96
634_R668_E1.5020.96
345_S518_E1.4980.96
380_I383_D1.4980.96
85_V91_V1.4790.96
71_P74_R1.4730.96
470_R509_I1.4720.96
275_P278_E1.4720.96
437_F460_A1.4510.95
403_A407_R1.4460.95
419_L423_E1.4450.95
179_E211_L1.4380.95
230_S234_V1.4340.95
662_R669_A1.4330.95
627_Q631_A1.4260.95
228_Y233_R1.4250.95
574_D577_D1.4240.95
265_V276_V1.4230.95
131_T266_L1.4190.95
466_M469_Q1.4130.94
470_R512_R1.4090.94
503_Q507_T1.4060.94
578_R587_A1.4050.94
415_D418_R1.3960.94
683_V698_S1.3950.94
54_V58_H1.3900.94
293_I303_V1.3840.94
295_E390_V1.3800.94
175_Q179_E1.3770.94
144_P190_T1.3730.94
395_I433_L1.3650.93
239_A242_N1.3620.93
465_L469_Q1.3560.93
535_D542_Y1.3420.93
490_P501_D1.3420.93
142_S250_D1.3220.92
463_I515_I1.3210.92
116_F293_I1.3150.92
143_V190_T1.3130.92
155_E158_V1.3130.92
524_D550_D1.3050.92
188_C193_I1.3000.92
351_I463_I1.2960.91
168_T204_A1.2890.91
113_N116_F1.2880.91
48_L54_V1.2850.91
51_L54_V1.2810.91
423_E426_S1.2770.91
47_D54_V1.2710.91
571_V591_R1.2680.90
531_Q534_S1.2660.90
267_D270_S1.2620.90
470_R473_A1.2580.90
155_E160_G1.2550.90
296_A386_Y1.2550.90
574_D591_R1.2470.90
585_P589_L1.2430.90
686_V690_L1.2410.89
439_Y445_A1.2410.89
296_A360_D1.2400.89
521_A537_G1.2370.89
401_I429_L1.2360.89
613_N650_Y1.2310.89
69_R72_G1.2270.89
145_V196_T1.2220.89
464_L486_I1.2210.89
398_R426_S1.2150.88
250_D325_G1.2100.88
121_R125_E1.2100.88
377_G380_I1.1980.88
190_T250_D1.1940.88
230_S235_G1.1930.88
154_E174_V1.1920.88
52_Q56_D1.1900.87
434_V453_H1.1830.87
402_K406_R1.1820.87
661_D664_A1.1810.87
196_T200_M1.1770.87
38_A78_E1.1760.87
223_A229_S1.1740.87
268_L272_S1.1740.87
376_L379_S1.1730.87
372_D377_G1.1710.87
243_V271_R1.1700.87
589_L695_W1.1670.86
156_L164_T1.1640.86
225_R230_S1.1620.86
595_A598_E1.1620.86
142_S190_T1.1580.86
664_A668_E1.1570.86
34_R82_A1.1510.86
231_Y234_V1.1470.85
333_V530_P1.1430.85
55_Y94_L1.1390.85
295_E299_R1.1340.85
346_S537_G1.1340.85
246_R250_D1.1330.85
341_E521_A1.1330.85
344_F350_N1.1320.85
72_G301_V1.1300.85
527_A536_A1.1290.84
229_S232_G1.1230.84
63_A84_D1.1190.84
361_V385_G1.1170.84
379_S455_A1.1150.84
554_V557_I1.1080.83
374_P379_S1.1040.83
615_V629_V1.1010.83
52_Q63_A1.1000.83
430_K438_G1.1000.83
139_L174_V1.1000.83
236_H239_A1.0990.83
405_I419_L1.0960.83
534_S558_E1.0960.83
596_I600_Q1.0960.83
255_F259_E1.0910.82
630_A633_K1.0900.82
434_V482_I1.0780.82
592_L596_I1.0760.81
339_V646_Q1.0680.81
568_I685_A1.0660.81
467_A486_I1.0640.81
408_E422_L1.0640.81
69_R297_N1.0630.81
437_F555_R1.0580.80
565_P681_Q1.0570.80
139_L156_L1.0560.80
495_D524_D1.0540.80
137_S181_H1.0530.80
341_E537_G1.0520.80
636_R642_V1.0500.80
66_M69_R1.0470.80
480_H487_W1.0460.80
39_A81_L1.0440.79
214_W217_V1.0400.79
74_R364_C1.0350.79
110_A310_H1.0300.79
563_S613_N1.0300.79
567_F682_L1.0300.79
492_P498_D1.0280.78
328_I457_N1.0260.78
289_T439_Y1.0260.78
88_I92_T1.0260.78
434_V437_F1.0230.78
463_I467_A1.0230.78
677_Y688_S1.0230.78
619_L633_K1.0210.78
38_A112_F1.0190.78
227_T233_R1.0140.77
374_P380_I1.0130.77
229_S233_R1.0100.77
629_V632_L1.0100.77
260_T263_D1.0090.77
564_T568_I1.0080.77
153_Y160_G1.0070.77
47_D55_Y1.0000.76
35_F91_V0.9990.76
95_A114_V0.9940.76
570_D574_D0.9930.76
425_R433_L0.9930.76
346_S431_W0.9890.76
245_G586_D0.9890.76
228_Y231_Y0.9850.75
560_R563_S0.9820.75
385_G389_D0.9810.75
347_L531_Q0.9790.75
659_S664_A0.9780.75
157_S161_D0.9780.75
434_V483_V0.9770.75
599_L682_L0.9750.75
466_M470_R0.9740.75
175_Q201_A0.9720.74
50_T53_S0.9670.74
566_P570_D0.9630.74
249_I254_T0.9630.74
323_D328_I0.9620.74
66_M70_R0.9570.73
333_V336_H0.9560.73
462_E466_M0.9550.73
197_L208_D0.9510.73
184_D213_R0.9490.73
285_G448_G0.9490.73
571_V682_L0.9490.73
485_S488_V0.9470.72
198_H202_T0.9460.72
528_F555_R0.9450.72
664_A667_H0.9440.72
236_H240_R0.9410.72
48_L56_D0.9410.72
400_E404_A0.9390.72
323_D453_H0.9390.72
190_T457_N0.9390.72
201_A209_F0.9390.72
182_D273_K0.9380.72
26_T30_N0.9370.72
225_R231_Y0.9370.72
677_Y681_Q0.9360.72
80_V302_L0.9360.72
566_P608_R0.9350.71
501_D505_L0.9330.71
345_S388_V0.9330.71
172_A176_G0.9320.71
155_E162_A0.9300.71
357_V428_A0.9270.71
623_S626_T0.9270.71
35_F94_L0.9260.71
180_A637_E0.9250.71
471_L486_I0.9240.71
480_H483_V0.9230.70
433_L439_Y0.9170.70
211_L496_E0.9150.70
378_Y382_D0.9130.70
155_E159_A0.9110.69
49_T54_V0.9090.69
243_V342_L0.9080.69
131_T565_P0.9070.69
34_R121_R0.9060.69
77_E82_A0.9040.69
67_V72_G0.9030.69
554_V576_L0.8990.68
82_A125_E0.8970.68
678_Y681_Q0.8950.68
650_Y678_Y0.8940.68
302_L469_Q0.8910.68
482_I535_D0.8900.68
629_V646_Q0.8890.68
499_R519_H0.8890.68
322_A443_S0.8880.67
262_L557_I0.8800.67
52_Q58_H0.8790.67
333_V458_A0.8790.67
558_E572_Q0.8790.67
368_S371_D0.8790.67
611_E681_Q0.8780.67
483_V487_W0.8770.67
226_S229_S0.8770.67
180_A507_T0.8760.66
433_L562_R0.8750.66
87_H93_P0.8740.66
338_N489_T0.8740.66
278_E286_N0.8730.66
201_A609_L0.8720.66
227_T230_S0.8710.66
391_L456_I0.8700.66
628_N631_A0.8690.66
143_V197_L0.8640.65
434_V480_H0.8630.65
344_F391_L0.8630.65
664_A672_T0.8610.65
496_E549_D0.8610.65
113_N125_E0.8600.65
618_P644_P0.8590.65
687_E691_S0.8570.65
480_H535_D0.8570.65
77_E80_V0.8550.65
200_M437_F0.8550.65
345_S431_W0.8520.64
64_T82_A0.8500.64
674_D685_A0.8490.64
687_E697_R0.8490.64
355_R515_I0.8480.64
42_P57_Q0.8480.64
554_V560_R0.8470.64
271_R429_L0.8430.63
341_E480_H0.8430.63
193_I457_N0.8430.63
85_V88_I0.8430.63
112_F302_L0.8420.63
480_H485_S0.8420.63
247_A251_E0.8400.63
441_G453_H0.8380.63
330_A353_C0.8370.63
225_R229_S0.8360.63
642_V646_Q0.8310.62
339_V489_T0.8300.62
662_R666_A0.8290.62
228_Y235_G0.8290.62
130_P134_S0.8270.62
35_F577_D0.8260.62
30_N63_A0.8250.62
138_T221_Q0.8230.62
566_P569_E0.8220.61
468_K599_L0.8210.61
197_L506_A0.8210.61
634_R659_S0.8210.61
504_T511_E0.8190.61
176_G179_E0.8190.61
665_L671_E0.8180.61
351_I515_I0.8180.61
227_T234_V0.8180.61
329_F441_G0.8180.61
71_P112_F0.8160.61
50_T56_D0.8160.61
140_R252_S0.8150.61
345_S516_R0.8130.61
85_V92_T0.8120.61
194_V645_G0.8110.60
442_F521_A0.8100.60
49_T473_A0.8090.60
423_E427_G0.8080.60
620_E636_R0.8080.60
229_S234_V0.8080.60
571_V575_C0.8080.60
339_V635_A0.8070.60
435_A518_E0.8060.60
651_V679_E0.8060.60
487_W537_G0.8060.60
190_T246_R0.8040.60
139_L165_G0.8020.60
659_S668_E0.8020.60
437_F482_I0.8020.60
606_V673_Y0.8010.59
611_E688_S0.8010.59
664_A669_A0.8000.59
153_Y161_D0.8000.59
434_V535_D0.7990.59
305_W446_K0.7990.59
349_P556_G0.7960.59
189_S255_F0.7950.59
90_R94_L0.7950.59
144_P247_A0.7940.59
397_A400_E0.7920.59
54_V57_Q0.7900.58
187_V352_I0.7900.58
190_T325_G0.7890.58
192_E281_W0.7850.58
93_P97_Q0.7850.58
358_S565_P0.7850.58
476_W513_V0.7840.58
92_T95_A0.7840.58
268_L284_I0.7830.58
564_T684_R0.7830.58
91_V95_A0.7820.58
437_F483_V0.7820.58
140_R187_V0.7810.58
87_H92_T0.7790.57
21_D66_M0.7770.57
635_A638_Q0.7770.57
454_E540_T0.7760.57
87_H90_R0.7760.57
590_G593_E0.7730.57
143_V193_I0.7710.57
51_L56_D0.7700.56
660_R664_A0.7680.56
184_D563_S0.7660.56
557_I572_Q0.7660.56
50_T66_M0.7650.56
342_L498_D0.7630.56
98_A109_L0.7610.56
559_A572_Q0.7600.55
242_N245_G0.7600.55
578_R581_A0.7590.55
289_T292_Q0.7570.55
47_D58_H0.7570.55
357_V452_C0.7560.55
153_Y159_A0.7560.55
165_G496_E0.7560.55
292_Q428_A0.7550.55
70_R186_L0.7550.55
339_V479_V0.7540.55
398_R438_G0.7530.55
405_I423_E0.7530.55
327_F464_L0.7510.55
171_L201_A0.7490.54
88_I125_E0.7490.54
336_H350_N0.7480.54
535_D541_K0.7470.54
173_A177_A0.7470.54
344_F394_I0.7450.54
225_R233_R0.7440.54
67_V70_R0.7430.54
464_L523_Y0.7420.54
130_P273_K0.7420.54
176_G590_G0.7410.54
247_A250_D0.7410.54
438_G556_G0.7410.54
510_T513_V0.7410.54
141_L194_V0.7410.54
69_R125_E0.7390.53
669_A672_T0.7370.53
510_T531_Q0.7360.53
342_L505_L0.7360.53
156_L177_A0.7330.53
523_Y568_I0.7320.53
94_L102_S0.7320.53
79_A590_G0.7310.53
560_R564_T0.7300.52
185_V590_G0.7290.52
331_P461_R0.7280.52
610_V651_V0.7250.52
453_H555_R0.7240.52
127_G180_A0.7210.52
406_R423_E0.7210.52
329_F481_G0.7210.52
446_K558_E0.7180.51
39_A55_Y0.7180.51
680_T684_R0.7170.51
87_H100_Q0.7160.51
272_S526_V0.7160.51
614_R643_H0.7140.51
442_F553_K0.7120.51
357_V440_Q0.7120.51
642_V647_D0.7110.51
430_K556_G0.7110.51
204_A302_L0.7110.51
289_T306_N0.7090.50
47_D51_L0.7090.50
144_P457_N0.7090.50
558_E561_Q0.7090.50
345_S446_K0.7080.50
529_V616_S0.7070.50
398_R430_K0.7070.50
401_I422_L0.7060.50
530_P555_R0.7060.50
567_F674_D0.7050.50
362_I449_R0.7050.50
568_I681_Q0.7040.50
681_Q684_R0.7020.50
354_T514_E0.7010.50
157_S160_G0.7010.50
38_A58_H0.6980.49
538_A581_A0.6980.49
611_E677_Y0.6970.49
75_R80_V0.6970.49
224_S227_T0.6960.49
48_L51_L0.6960.49
190_T482_I0.6950.49
509_I636_R0.6940.49
55_Y58_H0.6940.49
143_V246_R0.6940.49
552_F577_D0.6940.49
173_A180_A0.6940.49
34_R118_R0.6920.49
448_G647_D0.6890.48
68_A215_P0.6890.48
69_R302_L0.6890.48
473_A500_E0.6880.48
287_V627_Q0.6840.48
41_D64_T0.6820.48
359_P572_Q0.6810.48
449_R553_K0.6800.47
177_A181_H0.6800.47
23_A27_E0.6800.47
342_L506_A0.6780.47
95_A100_Q0.6770.47
114_V305_W0.6770.47
615_V619_L0.6760.47
358_S361_V0.6760.47
267_D406_R0.6750.47
359_P447_F0.6750.47
457_N460_A0.6740.47
140_R251_E0.6720.47
85_V98_A0.6720.47
93_P551_D0.6710.47
446_K688_S0.6690.46
63_A66_M0.6690.46
323_D441_G0.6680.46
510_T517_L0.6680.46
100_Q218_D0.6650.46
326_G457_N0.6650.46
283_S442_F0.6640.46
661_D667_H0.6630.46
42_P48_L0.6630.46
166_S214_W0.6620.46
112_F472_E0.6620.46
143_V154_E0.6610.46
40_R57_Q0.6610.46
304_P325_G0.6610.46
142_S457_N0.6600.45
193_I325_G0.6600.45
207_D396_D0.6600.45
501_D699_N0.6600.45
440_Q447_F0.6600.45
604_V609_L0.6590.45
52_Q65_E0.6590.45
662_R671_E0.6580.45
453_H482_I0.6580.45
286_N326_G0.6560.45
428_A460_A0.6560.45
215_P577_D0.6560.45
441_G628_N0.6550.45
32_T62_V0.6550.45
664_A671_E0.6540.45
61_V64_T0.6540.45
179_E210_S0.6540.45
508_E512_R0.6530.45
49_T66_M0.6520.45
205_G574_D0.6500.44
571_V686_V0.6500.44
453_H617_K0.6500.44
483_V535_D0.6490.44
88_I114_V0.6490.44
227_T231_Y0.6490.44
167_S170_I0.6480.44
248_I517_L0.6470.44
536_A580_D0.6460.44
498_D502_L0.6450.44
378_Y381_C0.6450.44
535_D540_T0.6450.44
157_S163_V0.6440.44
94_L207_D0.6430.44
32_T37_V0.6420.44
632_L674_D0.6420.44
228_Y234_V0.6420.44
471_L528_F0.6420.44
141_L186_L0.6420.44
113_N297_N0.6410.44
186_L298_D0.6400.44
67_V71_P0.6380.43
228_Y232_G0.6360.43
303_V346_S0.6360.43
373_V379_S0.6360.43
193_I482_I0.6350.43
409_T416_E0.6350.43
509_I643_H0.6350.43
272_S291_I0.6340.43
52_Q57_Q0.6340.43
508_E693_L0.6340.43
299_R386_Y0.6330.43
431_W456_I0.6320.43
496_E500_E0.6310.43
375_G378_Y0.6300.43
359_P529_V0.6300.43
282_A452_C0.6300.43
418_R422_L0.6290.42
331_P395_I0.6290.42
138_T187_V0.6280.42
530_P689_V0.6280.42
374_P382_D0.6280.42
438_G484_D0.6270.42
62_V95_A0.6270.42
142_S247_A0.6270.42
480_H532_R0.6260.42
226_S230_S0.6260.42
336_H479_V0.6260.42
388_V562_R0.6250.42
158_V162_A0.6230.42
128_A514_E0.6230.42
536_A579_L0.6220.42
564_T681_Q0.6220.42
617_K621_G0.6220.42
337_E585_P0.6210.42
98_A102_S0.6200.42
350_N480_H0.6200.42
205_G511_E0.6190.41
653_V690_L0.6190.41
346_S349_P0.6190.41
501_D504_T0.6180.41
268_L610_V0.6180.41
83_V203_D0.6160.41
341_E481_G0.6160.41
97_Q551_D0.6160.41
662_R668_E0.6160.41
178_L211_L0.6150.41
58_H215_P0.6150.41
469_Q670_I0.6140.41
588_V693_L0.6130.41
568_I684_R0.6120.41
430_K484_D0.6120.41
327_F521_A0.6120.41
221_Q224_S0.6110.41
128_A134_S0.6110.41
264_G557_I0.6110.41
637_E682_L0.6110.41
139_L183_P0.6110.41
344_F351_I0.6090.40
442_F525_W0.6080.40
471_L505_L0.6070.40
144_P415_D0.6070.40
398_R461_R0.6070.40
89_D96_R0.6070.40
502_L506_A0.6060.40
507_T686_V0.6050.40
299_R459_F0.6050.40
62_V71_P0.6050.40
528_F553_K0.6050.40
37_V54_V0.6040.40
51_L456_I0.6040.40
439_Y447_F0.6030.40
586_D589_L0.6030.40
115_D446_K0.6020.40
23_A35_F0.6020.40
601_A607_E0.6020.40
41_D54_V0.6020.40
26_T134_S0.6020.40
374_P458_A0.6020.40
56_D178_L0.6010.40
440_Q455_A0.6010.40
193_I200_M0.6010.40
287_V433_L0.6010.40
225_R232_G0.6000.40
350_N401_I0.6000.40
297_N303_V0.5990.40
87_H91_V0.5980.39
139_L519_H0.5980.39
279_L287_V0.5970.39
433_L563_S0.5970.39
277_Q281_W0.5960.39
397_A406_R0.5960.39
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32_T84_D0.5950.39
586_D590_G0.5940.39
344_F480_H0.5930.39
287_V359_P0.5930.39
325_G435_A0.5930.39
407_R503_Q0.5920.39
291_I564_T0.5920.39
494_V498_D0.5920.39
493_D497_E0.5910.39
346_S361_V0.5910.39
36_Y170_I0.5900.39
94_L100_Q0.5900.39
197_L258_G0.5890.39
172_A206_V0.5880.38
589_L699_N0.5880.38
171_L377_G0.5880.38
37_V56_D0.5870.38
53_S171_L0.5870.38
188_C482_I0.5860.38
329_F560_R0.5860.38
131_T262_L0.5860.38
285_G359_P0.5850.38
120_F131_T0.5840.38
121_R124_L0.5830.38
382_D416_E0.5830.38
48_L66_M0.5820.38
49_T55_Y0.5820.38
165_G169_D0.5810.38
185_V257_Y0.5810.38
483_V532_R0.5810.38
591_R632_L0.5800.38
267_D523_Y0.5800.38
63_A67_V0.5800.38
527_A692_P0.5800.38
124_L565_P0.5800.38
401_I404_A0.5800.38
120_F290_A0.5790.38
213_R216_D0.5770.37
505_L517_L0.5770.37
482_I531_Q0.5770.37
453_H483_V0.5770.37
569_E573_R0.5770.37
156_L160_G0.5770.37
42_P52_Q0.5760.37
224_S231_Y0.5760.37
95_A99_R0.5760.37
593_E599_L0.5750.37
63_A302_L0.5740.37
157_S162_A0.5740.37
53_S64_T0.5720.37
487_W526_V0.5710.37
68_A92_T0.5710.37
562_R647_D0.5710.37
323_D454_E0.5710.37
269_V274_N0.5710.37
346_S485_S0.5700.37
178_L469_Q0.5690.37
189_S246_R0.5690.37
77_E300_G0.5680.37
66_M71_P0.5680.37
278_E301_V0.5680.37
441_G481_G0.5680.37
674_D678_Y0.5680.37
241_Y245_G0.5680.37
481_G488_V0.5680.37
226_S235_G0.5670.37
460_A531_Q0.5660.36
61_V72_G0.5650.36
339_V502_L0.5650.36
128_A204_A0.5650.36
26_T603_N0.5640.36
496_E507_T0.5640.36
579_L642_V0.5630.36
164_T403_A0.5620.36
171_L340_H0.5620.36
231_Y235_G0.5600.36
499_R503_Q0.5600.36
161_D253_N0.5590.36
641_A686_V0.5590.36
594_R597_D0.5590.36
64_T551_D0.5580.36
439_Y487_W0.5580.36
32_T53_S0.5570.36
93_P99_R0.5570.36
439_Y453_H0.5560.35
325_G441_G0.5560.35
185_V618_P0.5560.35
493_D500_E0.5550.35
95_A98_A0.5550.35
51_L68_A0.5540.35
181_H651_V0.5540.35
674_D689_V0.5540.35
428_A572_Q0.5540.35
272_S523_Y0.5540.35
65_E84_D0.5540.35
168_T598_E0.5540.35
326_G402_K0.5530.35
494_V601_A0.5520.35
174_V242_N0.5510.35
402_K472_E0.5510.35
170_I604_V0.5510.35
473_A673_Y0.5500.35
102_S108_D0.5500.35
541_K549_D0.5500.35
174_V207_D0.5500.35
91_V125_E0.5490.35
425_R429_L0.5490.35
508_E594_R0.5480.35
433_L436_C0.5470.35
145_V448_G0.5470.35
582_T700_I0.5460.35
69_R73_F0.5460.35
34_R113_N0.5450.34
267_D287_V0.5450.34
99_R637_E0.5440.34
276_V293_I0.5440.34
588_V592_L0.5440.34
94_L698_S0.5440.34
70_R384_R0.5430.34
534_S561_Q0.5420.34
42_P50_T0.5410.34
41_D66_M0.5410.34
72_G75_R0.5410.34
26_T42_P0.5410.34
38_A110_A0.5400.34
335_L692_P0.5390.34
540_T550_D0.5390.34
42_P58_H0.5380.34
52_Q55_Y0.5380.34
499_R507_T0.5380.34
440_Q568_I0.5380.34
202_T620_E0.5380.34
345_S510_T0.5370.34
485_S537_G0.5370.34
339_V526_V0.5360.34
522_H528_F0.5350.34
200_M453_H0.5330.33
71_P80_V0.5330.33
500_E503_Q0.5330.33
663_V666_A0.5330.33
32_T72_G0.5330.33
124_L571_V0.5320.33
98_A101_L0.5320.33
70_R73_F0.5310.33
302_L308_W0.5310.33
68_A72_G0.5310.33
613_N628_N0.5310.33
41_D68_A0.5300.33
408_E419_L0.5300.33
49_T58_H0.5300.33
166_S172_A0.5300.33
515_I648_I0.5290.33
328_I482_I0.5280.33
659_S666_A0.5280.33
494_V607_E0.5270.33
244_P247_A0.5270.33
409_T419_L0.5270.33
352_I387_L0.5270.33
65_E77_E0.5270.33
246_R434_V0.5270.33
404_A407_R0.5260.33
397_A476_W0.5260.33
359_P440_Q0.5250.33
354_T359_P0.5240.33
635_A642_V0.5240.33
403_A621_G0.5230.33
171_L325_G0.5230.33
67_V82_A0.5230.33
166_S574_D0.5220.32
374_P455_A0.5220.32
358_S385_G0.5210.32
138_T594_R0.5210.32
599_L604_V0.5210.32
57_Q594_R0.5200.32
351_I455_A0.5200.32
135_E209_F0.5190.32
56_D65_E0.5190.32
166_S204_A0.5190.32
175_Q210_S0.5180.32
159_A162_A0.5180.32
478_V481_G0.5180.32
266_L270_S0.5180.32
324_R616_S0.5170.32
263_D267_D0.5170.32
372_D378_Y0.5170.32
345_S433_L0.5170.32
123_C130_P0.5170.32
128_A570_D0.5170.32
367_H370_R0.5160.32
82_A300_G0.5150.32
143_V196_T0.5150.32
83_V640_L0.5140.32
499_R505_L0.5140.32
181_H270_S0.5130.32
267_D397_A0.5120.32
344_F678_Y0.5120.32
224_S228_Y0.5110.31
469_Q604_V0.5110.31
47_D102_S0.5110.31
415_D419_L0.5100.31
88_I94_L0.5100.31
96_R100_Q0.5090.31
437_F480_H0.5090.31
296_A440_Q0.5090.31
606_V614_R0.5090.31
484_D556_G0.5080.31
423_E517_L0.5080.31
236_H244_P0.5080.31
559_A685_A0.5080.31
379_S383_D0.5080.31
189_S296_A0.5070.31
349_P438_G0.5070.31
487_W553_K0.5070.31
445_A537_G0.5060.31
199_E639_D0.5060.31
593_E700_I0.5060.31
384_R662_R0.5050.31
469_Q472_E0.5040.31
343_D484_D0.5040.31
224_S230_S0.5040.31
574_D598_E0.5030.31
498_D501_D0.5030.31
144_P195_P0.5030.31
340_H488_V0.5030.31
64_T71_P0.5020.31
69_R466_M0.5020.31
262_L429_L0.5020.31
331_P464_L0.5020.31
358_S433_L0.5020.31
668_E672_T0.5010.31
502_L565_P0.5010.31
663_V669_A0.5000.31
354_T440_Q0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1qhtA 1 0.8781 100 0.228 Contact Map
3iayA 1 0.9446 100 0.23 Contact Map
4qclA 1 0.9446 100 0.268 Contact Map
4fvmA 1 0.8975 100 0.27 Contact Map
2gv9A 1 0.9238 100 0.276 Contact Map
1s5jA 1 0.7895 100 0.288 Contact Map
3k59A 1 0.8878 100 0.291 Contact Map
4m8oA 1 0.9501 100 0.302 Contact Map
3qexA 1 0.9114 100 0.338 Contact Map
2py5A 2 0.5748 100 0.701 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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