GREMLIN Database
RL24E - 50S ribosomal protein L24e
UniProt: P61120 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 62 (56)
Sequences: 249 (112)
Seq/√Len: 14.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
40_N45_R4.0471.00
10_C37_C3.3880.99
10_C33_C3.1740.99
33_C37_C3.0320.98
40_N43_L2.7890.97
20_T38_E2.5060.94
35_A39_K2.0460.84
10_C34_S1.9150.80
21_M29_T1.8930.79
20_T31_H1.8310.77
25_N46_E1.7350.73
53_T56_E1.5630.64
34_S37_C1.5090.61
20_T25_N1.4470.58
32_F41_A1.4360.57
51_E56_E1.4140.56
6_S13_D1.3980.55
46_E49_D1.2630.48
11_G27_G1.1350.41
14_I18_T1.0700.37
4_T13_D1.0500.36
12_D37_C1.0140.34
24_H30_V0.9640.32
15_E43_L0.9280.30
44_G56_E0.8940.29
30_V33_C0.8820.28
24_H28_S0.8710.28
6_S23_V0.8610.27
5_R45_R0.8610.27
11_G23_V0.8550.27
16_P22_F0.8450.26
23_V47_P0.8350.26
15_E18_T0.8350.26
35_A57_E0.7910.24
17_G58_V0.7750.23
51_E57_E0.7720.23
18_T21_M0.7710.23
12_D47_P0.7660.23
25_N49_D0.7640.23
11_G30_V0.7590.23
47_P53_T0.7270.22
46_E54_D0.7140.21
14_I21_M0.7020.21
41_A57_E0.7010.21
32_F53_T0.6970.20
35_A42_D0.6970.20
27_G45_R0.6940.20
9_Y24_H0.6790.20
22_F35_A0.6780.20
47_P54_D0.6710.20
28_S54_D0.6470.19
21_M50_V0.6440.19
55_E58_V0.6390.18
9_Y40_N0.6370.18
3_Q56_E0.6340.18
11_G21_M0.6220.18
5_R54_D0.6160.18
38_E48_R0.6150.18
25_N50_V0.6140.18
27_G43_L0.5990.17
13_D45_R0.5940.17
26_D42_D0.5830.17
31_H58_V0.5800.17
36_K48_R0.5790.16
25_N53_T0.5750.16
30_V47_P0.5680.16
17_G23_V0.5660.16
14_I27_G0.5600.16
5_R27_G0.5600.16
3_Q37_C0.5540.16
28_S55_E0.5510.16
30_V46_E0.5480.16
22_F34_S0.5470.16
15_E48_R0.5460.15
22_F43_L0.5420.15
13_D28_S0.5350.15
46_E55_E0.5350.15
6_S12_D0.5190.15
5_R55_E0.5120.15
9_Y41_A0.5110.14
38_E58_V0.5100.14
36_K47_P0.5040.14
11_G29_T0.5040.14
12_D34_S0.5000.14
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j21V 1 1 99.9 0.18 Contact Map
3j65p 1 0.9839 99.9 0.182 Contact Map
4a17T 1 0.9839 99.9 0.183 Contact Map
1vx70 1 0.9839 99.9 0.191 Contact Map
3j61W 1 1 99.9 0.192 Contact Map
4w20W 1 0.9839 99.9 0.198 Contact Map
4ujrJ 1 0.9839 99.9 0.198 Contact Map
3j39W 1 0.9839 99.9 0.198 Contact Map
1vq8U 1 0.8548 99.9 0.209 Contact Map
3zf7Y 1 0.9839 99.9 0.255 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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