ATKA - HALSA - GREMLIN Contacts

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ATKA - Potassium-transporting ATPase A chain

UniProt:	P57684	Sequences: MASPPPIVEYAVFFTILAVLVFVAGEYLAWVYREQANSDHRPPGYLSWFERLDEIFTPIENGLYRLSGINPRREMTWKGYLKAVLVFNVCIWVLLFVVLMFQDALPMNFVGVGGESWDLAFHTASSFTSNTNQQHYSGETLSVFTHTFGIGIAMFLTPATGLALMPAFARAFTNKEDPRLGNFYENVVRGLVRFLLPISLLIAIILMAEGSVQTILGGQLTANTFTMGIQNIRIGPHAGIEAIKMFGTNGGGINAANAATAFENPTPLSNLVLTLAMPIGTFSAIYAWGAWVGNRSHGVAIVAAFFVIYMALTGVAVVGETGTNAGMVVTGNGLHVDQTVGNMEGKETRFGPTASAIWGLSTTGTTNGGVNSMHNSWTALGAFSLLFAFATNNISNGVGTGLLNILMFVILTAFIGALMIGRRPQYLGKKLEWQEMRYVFVVILVLPILVLIPQAAAVVYQGAIDSMNNPGFRGFSEVLYEFFSASANNGSGFEGLGDGTLFFNLVNGVQVLLARYVPITAQLAIAGYLANKKVSPESKGSLDTDTPAFVGLLIGVIIIVSALVFLPALVFGPIGELLSGGI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	582 (550)
Sequences:	1429 (737)
Seq/√Len:	31.4

ECOLI - ATKA
HALSA - ATKA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
482_F	506_V	5.030	1.00
485_A	507_N	4.489	1.00
214_T	234_I	4.435	1.00
372_S	377_W	4.216	1.00
96_F	100_M	3.917	1.00
386_L	476_S	3.791	1.00
457_A	502_F	3.698	1.00
95_L	149_G	3.698	1.00
28_L	194_F	3.579	1.00
206_L	273_L	3.528	1.00
355_S	372_S	3.453	1.00
99_L	145_T	3.391	1.00
32_Y	162_L	3.389	1.00
21_V	286_Y	3.289	1.00
144_F	148_F	3.282	1.00
119_L	135_H	3.259	1.00
294_N	545_D	3.151	1.00
304_A	554_I	3.110	1.00
74_E	179_R	3.082	1.00
88_N	160_T	3.030	1.00
28_L	287_A	2.936	1.00
237_H	241_E	2.878	1.00
32_Y	190_G	2.877	1.00
202_I	272_V	2.839	1.00
74_E	174_N	2.816	1.00
202_I	242_A	2.801	1.00
205_I	272_V	2.801	1.00
202_I	276_A	2.800	1.00
99_L	115_E	2.744	1.00
135_H	498_D	2.716	1.00
115_E	145_T	2.699	1.00
162_L	190_G	2.687	1.00
320_E	346_K	2.666	1.00
121_F	508_G	2.594	1.00
390_A	483_F	2.514	1.00
31_V	194_F	2.488	0.99
143_V	219_Q	2.482	0.99
499_G	504_N	2.465	0.99
209_E	266_T	2.449	0.99
98_V	144_F	2.434	0.99
137_S	255_A	2.415	0.99
358_W	369_G	2.359	0.99
103_D	114_G	2.341	0.99
358_W	367_N	2.237	0.99
434_Q	438_Y	2.227	0.99
245_M	367_N	2.224	0.99
173_T	292_V	2.216	0.99
16_I	271_L	2.198	0.99
142_S	145_T	2.189	0.99
378_T	381_G	2.167	0.99
312_L	388_A	2.124	0.98
458_V	478_V	2.120	0.98
467_M	478_V	2.110	0.98
517_V	521_A	2.095	0.98
323_T	378_T	2.081	0.98
166_P	287_A	2.069	0.98
97_V	101_F	2.056	0.98
494_E	498_D	2.053	0.98
402_L	406_L	2.052	0.98
245_M	369_G	2.047	0.98
453_P	506_V	2.022	0.98
84_V	164_L	2.000	0.97
115_E	141_L	1.987	0.97
119_L	499_G	1.946	0.97
449_L	486_S	1.916	0.97
432_E	532_K	1.909	0.97
245_M	358_W	1.906	0.97
30_W	35_Q	1.893	0.96
121_F	505_L	1.889	0.96
118_D	504_N	1.880	0.96
32_Y	166_P	1.859	0.96
96_F	117_W	1.834	0.96
52_L	58_P	1.814	0.95
389_F	487_A	1.803	0.95
237_H	254_N	1.784	0.95
304_A	550_V	1.781	0.95
450_V	487_A	1.754	0.95
91_I	160_T	1.743	0.94
20_L	275_L	1.742	0.94
278_P	361_S	1.737	0.94
337_D	340_V	1.729	0.94
297_H	544_T	1.726	0.94
172_F	288_W	1.722	0.94
206_L	211_S	1.719	0.94
309_Y	361_S	1.709	0.94
300_A	550_V	1.703	0.94
212_V	234_I	1.699	0.94
518_P	521_A	1.691	0.93
117_W	121_F	1.687	0.93
466_S	497_G	1.687	0.93
294_N	297_H	1.684	0.93
466_S	500_T	1.680	0.93
375_N	469_N	1.670	0.93
18_A	302_V	1.660	0.93
468_N	477_E	1.659	0.93
24_A	283_S	1.656	0.93
62_G	66_L	1.654	0.93
509_V	513_L	1.650	0.92
135_H	481_E	1.645	0.92
81_L	523_L	1.644	0.92
100_M	117_W	1.643	0.92
99_L	141_L	1.637	0.92
486_S	510_Q	1.637	0.92
343_M	348_T	1.635	0.92
446_L	565_F	1.611	0.92
107_M	144_F	1.609	0.91
258_A	273_L	1.606	0.91
70_N	73_R	1.602	0.91
496_L	503_F	1.599	0.91
454_Q	479_L	1.598	0.91
98_V	145_T	1.588	0.91
463_A	466_S	1.572	0.91
101_F	104_A	1.549	0.90
104_A	114_G	1.540	0.90
316_A	360_L	1.528	0.89
209_E	269_S	1.528	0.89
22_F	286_Y	1.524	0.89
125_S	512_L	1.517	0.89
20_L	279_I	1.510	0.89
205_I	268_L	1.504	0.88
500_T	504_N	1.503	0.88
308_I	394_I	1.501	0.88
316_A	385_L	1.498	0.88
76_T	79_G	1.490	0.88
112_V	115_E	1.487	0.88
313_T	360_L	1.487	0.88
119_L	504_N	1.482	0.88
412_T	556_V	1.482	0.88
204_I	207_M	1.472	0.87
208_A	212_V	1.470	0.87
305_F	405_I	1.458	0.87
29_A	287_A	1.456	0.87
77_W	524_A	1.456	0.87
389_F	483_F	1.453	0.87
338_Q	341_G	1.452	0.87
381_G	385_L	1.452	0.87
370_V	373_M	1.445	0.86
26_E	290_A	1.442	0.86
17_L	275_L	1.435	0.86
213_Q	239_G	1.414	0.85
458_V	467_M	1.411	0.85
125_S	508_G	1.410	0.85
301_I	405_I	1.400	0.85
359_G	374_H	1.400	0.85
88_N	91_I	1.391	0.84
296_S	545_D	1.383	0.84
443_I	560_V	1.361	0.83
200_L	204_I	1.359	0.83
492_G	498_D	1.351	0.82
382_A	493_F	1.350	0.82
472_F	579_S	1.345	0.82
198_I	242_A	1.341	0.82
285_I	298_G	1.335	0.82
241_E	358_W	1.332	0.81
373_M	494_E	1.327	0.81
453_P	482_F	1.320	0.81
400_T	519_I	1.318	0.81
64_Y	188_V	1.309	0.80
133_Q	481_E	1.305	0.80
294_N	426_Y	1.299	0.80
143_V	253_I	1.290	0.79
117_W	505_L	1.280	0.79
13_F	271_L	1.278	0.79
300_A	304_A	1.274	0.78
461_Q	464_I	1.266	0.78
366_T	398_V	1.259	0.78
224_T	227_M	1.258	0.77
24_A	198_I	1.252	0.77
425_Q	541_S	1.246	0.77
400_T	403_L	1.243	0.77
214_T	219_Q	1.242	0.77
221_T	231_N	1.241	0.76
137_S	140_T	1.232	0.76
309_Y	364_G	1.229	0.76
141_L	150_I	1.221	0.75
290_A	295_R	1.216	0.75
118_D	501_L	1.216	0.75
278_P	365_T	1.209	0.75
312_L	384_S	1.206	0.74
420_I	541_S	1.201	0.74
359_G	372_S	1.195	0.74
453_P	510_Q	1.193	0.74
22_F	26_E	1.190	0.73
466_S	503_F	1.187	0.73
277_M	359_G	1.184	0.73
232_I	262_F	1.184	0.73
302_V	306_F	1.181	0.73
410_I	439_V	1.176	0.72
162_L	284_A	1.174	0.72
13_F	361_S	1.168	0.72
77_W	527_G	1.167	0.72
245_M	273_L	1.157	0.71
475_F	568_A	1.157	0.71
198_I	276_A	1.150	0.71
286_Y	299_V	1.149	0.71
16_I	275_L	1.148	0.71
55_I	58_P	1.145	0.70
96_F	121_F	1.142	0.70
198_I	202_I	1.139	0.70
380_L	577_L	1.135	0.70
91_I	153_A	1.133	0.70
362_T	374_H	1.133	0.70
439_V	525_I	1.133	0.70
110_V	219_Q	1.132	0.70
284_A	287_A	1.121	0.69
24_A	280_G	1.119	0.69
405_I	553_L	1.117	0.68
286_Y	290_A	1.115	0.68
425_Q	430_K	1.108	0.68
460_Y	463_A	1.108	0.68
479_L	568_A	1.106	0.68
75_M	83_A	1.105	0.68
81_L	520_T	1.104	0.68
209_E	268_L	1.103	0.67
303_A	550_V	1.100	0.67
377_W	381_G	1.098	0.67
481_E	492_G	1.096	0.67
359_G	377_W	1.096	0.67
64_Y	69_I	1.087	0.66
236_P	253_I	1.082	0.66
241_E	245_M	1.081	0.66
482_F	503_F	1.078	0.66
21_V	299_V	1.069	0.65
185_E	188_V	1.065	0.65
458_V	475_F	1.064	0.65
316_A	384_S	1.061	0.64
133_Q	492_G	1.060	0.64
221_T	229_I	1.057	0.64
407_M	442_V	1.055	0.64
141_L	145_T	1.055	0.64
456_A	506_V	1.053	0.64
452_I	456_A	1.051	0.64
95_L	153_A	1.049	0.64
309_Y	313_T	1.044	0.63
58_P	61_N	1.042	0.63
359_G	385_L	1.037	0.63
150_I	240_I	1.037	0.63
469_N	496_L	1.035	0.62
316_A	356_A	1.030	0.62
411_L	439_V	1.027	0.62
170_R	186_N	1.027	0.62
478_V	503_F	1.026	0.62
575_G	579_S	1.021	0.61
135_H	507_N	1.021	0.61
277_M	367_N	1.018	0.61
200_L	203_A	1.017	0.61
392_N	404_N	1.015	0.61
11_A	15_T	1.013	0.61
487_A	542_L	1.008	0.60
95_L	124_A	1.007	0.60
405_I	557_I	1.007	0.60
505_L	509_V	1.005	0.60
435_E	528_Y	1.005	0.60
464_I	467_M	1.003	0.60
415_I	542_L	1.000	0.60
375_N	473_R	0.999	0.60
433_W	437_R	0.994	0.59
177_D	530_A	0.990	0.59
128_T	153_A	0.990	0.59
59_I	62_G	0.988	0.59
28_L	32_Y	0.988	0.59
88_N	516_Y	0.988	0.59
206_L	358_W	0.987	0.59
274_T	361_S	0.983	0.58
56_F	193_R	0.983	0.58
162_L	398_V	0.982	0.58
315_V	318_V	0.981	0.58
524_A	527_G	0.980	0.58
235_G	253_I	0.979	0.58
277_M	366_T	0.977	0.58
362_T	370_V	0.975	0.58
556_V	559_I	0.974	0.58
214_T	262_F	0.968	0.57
21_V	285_I	0.968	0.57
467_M	470_P	0.963	0.57
449_L	513_L	0.963	0.57
156_L	187_V	0.962	0.57
364_G	395_S	0.961	0.57
408_F	557_I	0.961	0.57
336_V	340_V	0.959	0.57
380_L	383_F	0.956	0.56
6_P	10_Y	0.956	0.56
288_W	544_T	0.955	0.56
125_S	129_S	0.955	0.56
99_L	119_L	0.953	0.56
343_M	346_K	0.953	0.56
318_V	322_G	0.952	0.56
410_I	525_I	0.951	0.56
273_L	358_W	0.949	0.56
122_H	133_Q	0.949	0.56
256_A	367_N	0.947	0.56
92_W	125_S	0.946	0.55
101_F	114_G	0.945	0.55
248_T	366_T	0.944	0.55
107_M	215_I	0.944	0.55
439_V	566_L	0.943	0.55
150_I	154_M	0.942	0.55
551_G	555_G	0.939	0.55
154_M	240_I	0.933	0.54
481_E	507_N	0.931	0.54
337_D	341_G	0.930	0.54
57_T	61_N	0.927	0.54
285_I	305_F	0.927	0.54
172_F	430_K	0.927	0.54
307_V	550_V	0.919	0.53
73_R	79_G	0.918	0.53
53_D	193_R	0.916	0.53
314_G	318_V	0.914	0.53
425_Q	540_G	0.914	0.53
415_I	556_V	0.912	0.53
448_I	452_I	0.912	0.53
92_W	128_T	0.910	0.53
342_N	378_T	0.908	0.52
494_E	497_G	0.908	0.52
430_K	535_S	0.908	0.52
95_L	99_L	0.905	0.52
90_C	94_L	0.904	0.52
58_P	62_G	0.902	0.52
497_G	504_N	0.899	0.52
502_F	506_V	0.899	0.52
133_Q	494_E	0.898	0.52
162_L	194_F	0.896	0.51
360_L	384_S	0.895	0.51
226_T	229_I	0.895	0.51
154_M	392_N	0.895	0.51
281_T	395_S	0.893	0.51
94_L	98_V	0.892	0.51
234_I	262_F	0.892	0.51
80_Y	186_N	0.891	0.51
320_E	343_M	0.891	0.51
486_S	514_A	0.890	0.51
26_E	30_W	0.886	0.51
220_L	234_I	0.885	0.51
84_V	519_I	0.885	0.51
481_E	494_E	0.884	0.50
313_T	317_V	0.882	0.50
143_V	217_G	0.879	0.50
200_L	478_V	0.877	0.50
449_L	510_Q	0.875	0.50
163_A	190_G	0.869	0.49
132_N	249_N	0.868	0.49
374_H	377_W	0.865	0.49
24_A	279_I	0.865	0.49
141_L	255_A	0.862	0.49
172_F	535_S	0.861	0.49
92_W	512_L	0.860	0.49
211_S	258_A	0.858	0.48
370_V	374_H	0.858	0.48
241_E	367_N	0.857	0.48
316_A	381_G	0.856	0.48
64_Y	185_E	0.856	0.48
223_N	227_M	0.855	0.48
167_A	523_L	0.855	0.48
468_N	497_G	0.853	0.48
245_M	278_P	0.852	0.48
241_E	369_G	0.849	0.48
463_A	503_F	0.849	0.48
245_M	361_S	0.848	0.48
75_M	388_A	0.847	0.47
327_M	339_T	0.846	0.47
116_S	119_L	0.845	0.47
481_E	498_D	0.842	0.47
91_I	152_I	0.840	0.47
441_V	521_A	0.838	0.47
143_V	233_R	0.837	0.47
416_G	552_L	0.837	0.47
214_T	253_I	0.833	0.46
133_Q	498_D	0.831	0.46
233_R	254_N	0.831	0.46
359_G	362_T	0.830	0.46
28_L	283_S	0.830	0.46
266_T	269_S	0.830	0.46
165_M	367_N	0.830	0.46
391_T	558_I	0.829	0.46
84_V	160_T	0.829	0.46
147_T	236_P	0.818	0.45
135_H	492_G	0.815	0.45
166_P	291_W	0.814	0.45
522_Q	525_I	0.812	0.45
316_A	359_G	0.811	0.45
132_N	248_T	0.810	0.44
71_P	185_E	0.810	0.44
517_V	520_T	0.809	0.44
543_D	546_T	0.809	0.44
236_P	375_N	0.808	0.44
124_A	149_G	0.806	0.44
172_F	529_L	0.805	0.44
365_T	398_V	0.803	0.44
150_I	168_F	0.802	0.44
154_M	366_T	0.802	0.44
83_A	469_N	0.802	0.44
436_M	439_V	0.802	0.44
394_I	557_I	0.802	0.44
306_F	395_S	0.800	0.44
241_E	273_L	0.800	0.44
256_A	358_W	0.793	0.43
56_F	72_R	0.792	0.43
208_A	266_T	0.792	0.43
135_H	485_A	0.790	0.43
143_V	234_I	0.788	0.43
128_T	516_Y	0.788	0.43
378_T	385_L	0.785	0.42
13_F	275_L	0.784	0.42
277_M	365_T	0.783	0.42
13_F	365_T	0.783	0.42
559_I	566_L	0.782	0.42
57_T	222_A	0.781	0.42
188_V	191_L	0.781	0.42
288_W	292_V	0.780	0.42
224_T	228_G	0.778	0.42
407_M	439_V	0.777	0.42
454_Q	475_F	0.776	0.42
356_A	377_W	0.776	0.42
317_V	356_A	0.775	0.42
165_M	358_W	0.775	0.42
9_E	267_P	0.774	0.42
278_P	367_N	0.773	0.42
309_Y	454_Q	0.772	0.41
342_N	376_S	0.769	0.41
137_S	233_R	0.769	0.41
21_V	283_S	0.769	0.41
206_L	276_A	0.767	0.41
64_Y	193_R	0.764	0.41
166_P	190_G	0.764	0.41
311_A	314_G	0.762	0.41
320_E	381_G	0.759	0.40
100_M	409_V	0.759	0.40
52_L	55_I	0.757	0.40
217_G	234_I	0.755	0.40
169_A	402_L	0.753	0.40
150_I	392_N	0.752	0.40
299_V	303_A	0.749	0.40
245_M	365_T	0.749	0.40
132_N	247_G	0.747	0.39
280_G	398_V	0.745	0.39
277_M	361_S	0.744	0.39
174_N	177_D	0.744	0.39
369_G	400_T	0.743	0.39
468_N	494_E	0.743	0.39
355_S	377_W	0.743	0.39
98_V	115_E	0.742	0.39
317_V	353_T	0.741	0.39
327_M	338_Q	0.740	0.39
282_F	395_S	0.740	0.39
171_A	530_A	0.740	0.39
413_A	431_L	0.739	0.39
286_Y	295_R	0.739	0.39
301_I	305_F	0.738	0.39
442_V	518_P	0.733	0.38
25_G	287_A	0.733	0.38
403_L	522_Q	0.733	0.38
164_L	522_Q	0.732	0.38
151_G	373_M	0.730	0.38
388_A	400_T	0.726	0.38
203_A	239_G	0.726	0.38
143_V	214_T	0.725	0.38
254_N	260_T	0.723	0.38
255_A	494_E	0.721	0.37
240_I	366_T	0.719	0.37
277_M	362_T	0.719	0.37
19_V	22_F	0.717	0.37
19_V	23_V	0.716	0.37
159_A	191_L	0.715	0.37
274_T	367_N	0.713	0.37
346_K	381_G	0.712	0.37
25_G	29_A	0.712	0.37
141_L	151_G	0.712	0.37
237_H	367_N	0.711	0.37
288_W	426_Y	0.711	0.37
446_L	450_V	0.709	0.37
65_R	296_S	0.708	0.37
440_F	556_V	0.708	0.37
81_L	512_L	0.707	0.36
387_F	562_A	0.706	0.36
223_N	228_G	0.705	0.36
96_F	409_V	0.703	0.36
212_V	487_A	0.703	0.36
214_T	415_I	0.702	0.36
386_L	467_M	0.701	0.36
242_A	245_M	0.700	0.36
164_L	519_I	0.700	0.36
417_A	423_R	0.698	0.36
57_T	60_E	0.697	0.36
224_T	230_Q	0.695	0.36
312_L	316_A	0.695	0.36
95_L	152_I	0.694	0.35
309_Y	357_I	0.693	0.35
436_M	499_G	0.692	0.35
356_A	359_G	0.692	0.35
121_F	125_S	0.692	0.35
29_A	290_A	0.691	0.35
454_Q	496_L	0.690	0.35
217_G	232_I	0.688	0.35
464_I	468_N	0.687	0.35
207_M	211_S	0.687	0.35
88_N	435_E	0.687	0.35
560_V	564_V	0.685	0.35
383_F	390_A	0.685	0.35
256_A	369_G	0.683	0.35
510_Q	514_A	0.682	0.35
570_V	579_S	0.679	0.34
133_Q	507_N	0.679	0.34
153_A	392_N	0.678	0.34
112_V	145_T	0.677	0.34
135_H	494_E	0.675	0.34
15_T	201_L	0.675	0.34
153_A	240_I	0.674	0.34
377_W	385_L	0.674	0.34
290_A	293_G	0.674	0.34
277_M	309_Y	0.673	0.34
465_D	503_F	0.672	0.34
31_V	190_G	0.672	0.34
447_P	575_G	0.671	0.34
198_I	246_F	0.671	0.34
492_G	507_N	0.671	0.34
68_G	483_F	0.670	0.34
143_V	212_V	0.670	0.34
118_D	497_G	0.669	0.34
386_L	525_I	0.669	0.34
319_G	381_G	0.667	0.33
80_Y	170_R	0.667	0.33
364_G	506_V	0.666	0.33
154_M	398_V	0.665	0.33
445_V	513_L	0.664	0.33
84_V	183_F	0.662	0.33
477_E	492_G	0.661	0.33
497_G	500_T	0.661	0.33
135_H	503_F	0.661	0.33
100_M	121_F	0.660	0.33
297_H	426_Y	0.657	0.33
209_E	272_V	0.657	0.33
449_L	512_L	0.656	0.33
304_A	405_I	0.654	0.33
248_T	398_V	0.652	0.32
34_E	193_R	0.650	0.32
154_M	403_L	0.649	0.32
521_A	542_L	0.649	0.32
135_H	504_N	0.648	0.32
92_W	121_F	0.646	0.32
387_F	483_F	0.645	0.32
86_V	222_A	0.644	0.32
166_P	169_A	0.644	0.32
465_D	565_F	0.643	0.32
132_N	366_T	0.640	0.32
435_E	525_I	0.639	0.31
382_A	473_R	0.639	0.31
300_A	303_A	0.638	0.31
440_F	450_V	0.638	0.31
117_W	508_G	0.638	0.31
61_N	71_P	0.636	0.31
91_I	392_N	0.636	0.31
98_V	148_F	0.635	0.31
269_S	296_S	0.635	0.31
391_T	432_E	0.635	0.31
120_A	196_L	0.634	0.31
147_T	215_I	0.633	0.31
245_M	354_A	0.632	0.31
168_F	522_Q	0.632	0.31
475_F	542_L	0.631	0.31
154_M	393_N	0.631	0.31
203_A	242_A	0.630	0.31
113_G	117_W	0.629	0.31
309_Y	455_A	0.629	0.31
409_V	412_T	0.628	0.31
447_P	579_S	0.627	0.31
279_I	307_V	0.627	0.31
222_A	232_I	0.626	0.31
433_W	436_M	0.624	0.30
151_G	239_G	0.623	0.30
26_E	286_Y	0.623	0.30
312_L	387_F	0.623	0.30
245_M	277_M	0.622	0.30
17_L	282_F	0.622	0.30
58_P	566_L	0.622	0.30
110_V	233_R	0.622	0.30
205_I	269_S	0.622	0.30
232_I	277_M	0.621	0.30
119_L	500_T	0.621	0.30
99_L	135_H	0.621	0.30
453_P	507_N	0.621	0.30
541_S	544_T	0.621	0.30
167_A	171_A	0.620	0.30
282_F	285_I	0.616	0.30
274_T	358_W	0.616	0.30
137_S	301_I	0.615	0.30
107_M	427_L	0.615	0.30
392_N	403_L	0.613	0.30
28_L	166_P	0.613	0.30
83_A	183_F	0.612	0.30
72_R	296_S	0.612	0.30
485_A	504_N	0.612	0.30
114_G	120_A	0.611	0.30
219_Q	234_I	0.610	0.29
518_P	542_L	0.610	0.29
162_L	280_G	0.609	0.29
172_F	292_V	0.608	0.29
81_L	85_L	0.608	0.29
457_A	503_F	0.608	0.29
520_T	538_S	0.607	0.29
108_N	142_S	0.607	0.29
17_L	278_P	0.607	0.29
215_I	220_L	0.606	0.29
151_G	215_I	0.605	0.29
288_W	542_L	0.605	0.29
361_S	367_N	0.605	0.29
130_N	157_T	0.604	0.29
498_D	503_F	0.604	0.29
376_S	477_E	0.603	0.29
57_T	193_R	0.602	0.29
35_Q	58_P	0.602	0.29
19_V	303_A	0.602	0.29
121_F	513_L	0.601	0.29
23_V	412_T	0.600	0.29
221_T	452_I	0.600	0.29
135_H	467_M	0.599	0.29
87_F	91_I	0.598	0.29
63_L	67_S	0.597	0.29
206_L	272_V	0.597	0.29
385_L	388_A	0.597	0.29
85_L	89_V	0.596	0.29
192_V	559_I	0.596	0.29
308_I	312_L	0.595	0.28
264_N	270_N	0.595	0.28
352_P	356_A	0.595	0.28
111_G	232_I	0.594	0.28
120_A	124_A	0.594	0.28
32_Y	536_P	0.594	0.28
189_R	291_W	0.593	0.28
10_Y	313_T	0.593	0.28
501_L	505_L	0.592	0.28
82_K	459_V	0.591	0.28
156_L	198_I	0.591	0.28
83_A	232_I	0.590	0.28
16_I	19_V	0.590	0.28
91_I	154_M	0.588	0.28
240_I	392_N	0.588	0.28
317_V	357_I	0.588	0.28
176_E	533_K	0.588	0.28
348_T	559_I	0.588	0.28
498_D	507_N	0.588	0.28
255_A	575_G	0.588	0.28
548_A	551_G	0.588	0.28
287_A	291_W	0.586	0.28
400_T	404_N	0.586	0.28
15_T	31_V	0.584	0.28
156_L	183_F	0.584	0.28
154_M	249_N	0.583	0.28
92_W	440_F	0.583	0.28
194_F	283_S	0.582	0.28
212_V	237_H	0.581	0.28
21_V	282_F	0.580	0.27
473_R	493_F	0.577	0.27
505_L	508_G	0.577	0.27
119_L	498_D	0.577	0.27
10_Y	317_V	0.576	0.27
20_L	482_F	0.576	0.27
364_G	388_A	0.576	0.27
324_N	327_M	0.574	0.27
13_F	274_T	0.574	0.27
89_V	536_P	0.573	0.27
245_M	258_A	0.573	0.27
176_E	457_A	0.573	0.27
53_D	57_T	0.572	0.27
143_V	236_P	0.571	0.27
188_V	192_V	0.571	0.27
410_I	566_L	0.571	0.27
317_V	542_L	0.570	0.27
69_I	185_E	0.569	0.27
440_F	466_S	0.569	0.27
315_V	384_S	0.568	0.27
283_S	327_M	0.568	0.27
325_A	379_A	0.568	0.27
100_M	508_G	0.567	0.27
273_L	277_M	0.567	0.27
371_N	375_N	0.566	0.27
150_I	398_V	0.566	0.27
153_A	393_N	0.566	0.27
410_I	570_V	0.566	0.27
204_I	380_L	0.565	0.27
391_T	394_I	0.565	0.27
34_E	53_D	0.563	0.26
465_D	497_G	0.561	0.26
133_Q	393_N	0.561	0.26
315_V	380_L	0.561	0.26
29_A	32_Y	0.561	0.26
62_G	172_F	0.560	0.26
249_N	367_N	0.560	0.26
404_N	550_V	0.560	0.26
538_S	568_A	0.559	0.26
53_D	58_P	0.558	0.26
11_A	72_R	0.556	0.26
342_N	377_W	0.556	0.26
63_L	66_L	0.556	0.26
481_E	503_F	0.555	0.26
54_E	65_R	0.555	0.26
458_V	568_A	0.554	0.26
21_V	302_V	0.554	0.26
54_E	318_V	0.553	0.26
288_W	297_H	0.552	0.26
276_A	285_I	0.551	0.26
69_I	188_V	0.551	0.26
366_T	393_N	0.551	0.26
473_R	576_E	0.550	0.26
327_M	443_I	0.550	0.26
249_N	366_T	0.550	0.26
28_L	565_F	0.549	0.26
212_V	446_L	0.547	0.25
311_A	558_I	0.547	0.25
219_Q	231_N	0.546	0.25
133_Q	485_A	0.546	0.25
373_M	468_N	0.546	0.25
143_V	467_M	0.545	0.25
358_W	361_S	0.545	0.25
277_M	405_I	0.545	0.25
508_G	512_L	0.545	0.25
395_S	408_F	0.544	0.25
132_N	154_M	0.543	0.25
88_N	324_N	0.542	0.25
7_I	11_A	0.541	0.25
538_S	556_V	0.540	0.25
54_E	58_P	0.540	0.25
13_F	367_N	0.540	0.25
512_L	565_F	0.540	0.25
256_A	302_V	0.538	0.25
559_I	574_I	0.538	0.25
429_K	534_V	0.537	0.25
434_Q	528_Y	0.536	0.25
216_L	234_I	0.536	0.25
277_M	370_V	0.536	0.25
277_M	398_V	0.534	0.25
375_N	476_S	0.533	0.25
521_A	577_L	0.533	0.25
366_T	392_N	0.532	0.24
125_S	514_A	0.532	0.24
327_M	336_V	0.532	0.24
84_V	523_L	0.531	0.24
165_M	245_M	0.531	0.24
107_M	359_G	0.530	0.24
29_A	308_I	0.530	0.24
469_N	472_F	0.529	0.24
34_E	557_I	0.529	0.24
194_F	565_F	0.529	0.24
165_M	369_G	0.529	0.24
440_F	449_L	0.529	0.24
77_W	523_L	0.528	0.24
34_E	56_F	0.528	0.24
267_P	478_V	0.526	0.24
536_P	541_S	0.526	0.24
22_F	299_V	0.526	0.24
169_A	291_W	0.526	0.24
153_A	481_E	0.526	0.24
482_F	510_Q	0.525	0.24
83_A	436_M	0.525	0.24
282_F	286_Y	0.525	0.24
317_V	321_T	0.525	0.24
460_Y	558_I	0.524	0.24
217_G	292_V	0.524	0.24
307_V	311_A	0.524	0.24
137_S	575_G	0.524	0.24
463_A	502_F	0.522	0.24
25_G	286_Y	0.522	0.24
153_A	446_L	0.522	0.24
66_L	70_N	0.521	0.24
206_L	369_G	0.521	0.24
240_I	393_N	0.520	0.24
151_G	569_L	0.519	0.24
274_T	365_T	0.519	0.24
107_M	147_T	0.518	0.24
367_N	386_L	0.518	0.24
208_A	217_G	0.517	0.24
12_V	268_L	0.517	0.24
57_T	71_P	0.517	0.24
310_M	364_G	0.516	0.24
374_H	493_F	0.516	0.24
247_G	367_N	0.516	0.24
240_I	253_I	0.516	0.24
27_Y	82_K	0.515	0.23
28_L	190_G	0.515	0.23
373_M	493_F	0.515	0.23
245_M	266_T	0.515	0.23
9_E	21_V	0.515	0.23
214_T	446_L	0.515	0.23
54_E	57_T	0.514	0.23
111_G	565_F	0.514	0.23
132_N	398_V	0.514	0.23
423_R	430_K	0.514	0.23
467_M	477_E	0.514	0.23
241_E	514_A	0.514	0.23
450_V	578_L	0.512	0.23
408_F	411_L	0.512	0.23
13_F	277_M	0.512	0.23
387_F	558_I	0.511	0.23
72_R	262_F	0.511	0.23
17_L	164_L	0.511	0.23
245_M	359_G	0.511	0.23
295_R	327_M	0.510	0.23
241_E	262_F	0.509	0.23
248_T	367_N	0.509	0.23
101_F	105_L	0.508	0.23
137_S	256_A	0.508	0.23
357_I	412_T	0.507	0.23
88_N	402_L	0.507	0.23
118_D	499_G	0.507	0.23
494_E	503_F	0.505	0.23
477_E	494_E	0.505	0.23
92_W	513_L	0.505	0.23
172_F	191_L	0.505	0.23
65_R	83_A	0.505	0.23
59_I	216_L	0.504	0.23
280_G	533_K	0.504	0.23
294_N	539_K	0.504	0.23
9_E	12_V	0.503	0.23
275_L	279_I	0.503	0.23
180_L	294_N	0.503	0.23
152_I	168_F	0.502	0.23
492_G	503_F	0.502	0.23
297_H	427_L	0.502	0.23
152_I	240_I	0.501	0.23
99_L	114_G	0.501	0.23
533_K	536_P	0.501	0.23
308_I	554_I	0.501	0.23
222_A	230_Q	0.500	0.23
485_A	498_D	0.500	0.23
133_Q	392_N	0.500	0.23
303_A	476_S	0.500	0.23

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3pjzA	2	0.7388	100	0.819	Contact Map
4j7cI	2	0.6924	100	0.829	Contact Map
4um9B	2	0	8.3	0.99	Contact Map
2k3cA	1	0.0533	7.1	0.991	Contact Map
2k1eA	3	0.177	6.9	0.991	Contact Map
4xnjA	1	0.4966	5.3	0.991	Contact Map
2onkC	2	0.3402	4.9	0.991	Contact Map
2l92A	1	0.0687	4.9	0.991	Contact Map
4j05A	3	0.3952	4.1	0.992	Contact Map
3tx3A	2	0.2405	4.1	0.992	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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