GREMLIN Database
RS10 - 30S ribosomal protein S10
UniProt: P48854 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 102 (98)
Sequences: 1018 (445)
Seq/√Len: 44.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
5_R74_D5.5601.00
48_P63_H3.9851.00
51_K60_T3.9611.00
45_L68_V3.9211.00
30_T81_A3.8851.00
10_G16_L2.6851.00
48_P61_W2.6521.00
50_R53_P2.2921.00
52_S56_E2.1721.00
21_G25_E2.1371.00
16_L20_C1.7050.98
50_R54_D1.6340.97
50_R59_A1.5900.97
52_S55_G1.5470.96
13_P17_D1.4820.95
20_C35_S1.4710.95
33_K76_D1.4700.95
91_P96_I1.4310.94
40_L72_L1.4170.94
38_V87_R1.3680.92
50_R60_T1.3130.91
26_I29_K1.2900.90
6_V75_I1.2840.90
52_S58_T1.2820.90
44_T67_R1.2700.89
42_T69_H1.2640.89
25_E29_K1.2010.86
35_S66_M1.1910.86
60_T64_W1.1790.85
43_K70_K1.1770.85
52_S59_A1.1730.85
45_L66_M1.1570.84
55_G59_A1.1570.84
50_R68_V1.1420.83
50_R55_G1.1340.83
22_E89_Q1.1300.83
53_P56_E1.0960.81
6_V67_R1.0840.80
38_V72_L1.0510.78
3_Q35_S1.0280.76
7_R43_K1.0230.76
70_K73_I1.0190.76
10_G89_Q1.0160.75
27_A73_I0.9950.74
73_I83_R0.9630.71
38_V70_K0.9560.71
45_L48_P0.9440.70
3_Q16_L0.9420.70
8_L94_V0.9350.69
95_N100_L0.9350.69
46_E63_H0.9120.67
24_Q28_D0.9060.67
45_L49_S0.8960.66
16_L19_I0.8900.65
51_K64_W0.8880.65
35_S73_I0.8530.62
85_L99_V0.8480.62
45_L55_G0.8410.61
21_G78_D0.8180.59
75_I81_A0.8160.59
26_I86_M0.8160.59
79_E86_M0.8160.59
52_S60_T0.8130.58
47_V66_M0.8010.57
8_L16_L0.7950.57
29_K69_H0.7950.57
23_V99_V0.7930.56
13_P69_H0.7910.56
74_D88_I0.7860.56
50_R61_W0.7850.56
37_P71_R0.7820.55
43_K56_E0.7810.55
68_V72_L0.7740.55
84_Q87_R0.7670.54
8_L100_L0.7630.54
23_V26_I0.7620.53
16_L80_R0.7460.52
7_R14_D0.7320.51
15_D33_K0.7290.50
51_K54_D0.7290.50
32_V81_A0.7290.50
47_V68_V0.7280.50
53_P86_M0.7260.50
55_G61_W0.7260.50
39_P71_R0.7250.50
10_G43_K0.7240.50
22_E87_R0.7210.49
18_N22_E0.7130.49
35_S91_P0.7090.48
32_V78_D0.7030.48
45_L70_K0.7000.47
56_E59_A0.6990.47
16_L69_H0.6870.46
21_G94_V0.6860.46
22_E28_D0.6840.46
30_T85_L0.6820.46
52_S65_E0.6790.45
80_R96_I0.6770.45
68_V78_D0.6770.45
14_D17_D0.6760.45
15_D93_D0.6740.45
10_G66_M0.6720.45
7_R70_K0.6690.44
62_E79_E0.6540.43
26_I78_D0.6510.43
86_M97_E0.6510.43
24_Q66_M0.6340.41
17_D39_P0.6280.41
86_M96_I0.6250.40
3_Q72_L0.6240.40
56_E70_K0.6220.40
54_D61_W0.6070.39
7_R40_L0.5980.38
18_N95_N0.5960.38
82_L86_M0.5960.38
18_N82_L0.5930.37
12_D38_V0.5880.37
32_V98_I0.5870.37
15_D19_I0.5850.37
49_S55_G0.5780.36
47_V55_G0.5770.36
54_D58_T0.5760.36
19_I90_V0.5710.35
24_Q34_V0.5710.35
16_L66_M0.5710.35
12_D15_D0.5690.35
2_Q100_L0.5670.35
9_A97_E0.5650.35
26_I88_I0.5620.35
25_E100_L0.5590.34
56_E61_W0.5590.34
18_N28_D0.5440.33
34_V48_P0.5400.33
42_T50_R0.5370.32
26_I64_W0.5360.32
14_D29_K0.5350.32
43_K92_N0.5280.32
23_V31_G0.5220.31
69_H96_I0.5190.31
48_P54_D0.5190.31
30_T80_R0.5190.31
66_M70_K0.5150.31
25_E59_A0.5150.31
15_D83_R0.5140.30
65_E76_D0.5060.30
27_A85_L0.5030.30
88_I99_V0.5000.29
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j20L 1 1 100 0.175 Contact Map
3j7aN 1 0.951 100 0.183 Contact Map
3j60U 1 1 100 0.188 Contact Map
4ujpV 1 1 100 0.19 Contact Map
4bpeJ 1 1 100 0.196 Contact Map
3zeyQ 1 1 100 0.201 Contact Map
4w23U 1 1 100 0.21 Contact Map
3bbnJ 1 0.9608 100 0.223 Contact Map
4rb5J 1 0.9412 100 0.225 Contact Map
3w1yC 1 0.8725 100 0.24 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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