GREMLIN Database
RS19 - 30S ribosomal protein S19
UniProt: P15010 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 140 (133)
Sequences: 397 (212)
Seq/√Len: 18.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
85_V107_I5.4221.00
31_V35_L4.6751.00
59_R83_E4.3421.00
18_H26_M3.7791.00
112_G117_T2.3520.95
54_V111_L2.3270.95
15_Y36_P2.2460.94
125_Q128_I2.0690.90
43_I81_L2.0530.90
35_L39_Q2.0170.89
94_G123_H2.0030.89
39_Q110_Y1.9500.88
29_E32_A1.8520.85
133_S137_V1.8470.84
45_R76_R1.7590.81
129_G138_P1.7150.80
78_M89_F1.6330.76
21_D24_Q1.6230.76
9_R12_E1.6050.75
109_H112_G1.5720.73
134_S140_K1.5620.73
124_G137_V1.5320.71
102_V111_L1.5210.71
51_H77_D1.4920.69
19_D22_E1.4850.69
132_R135_K1.4770.68
88_T99_R1.4650.68
36_P39_Q1.4450.67
132_R137_V1.4420.66
58_A103_Q1.4230.65
70_P90_A1.4230.65
32_A92_Y1.4050.64
118_R129_G1.4040.64
39_Q79_P1.3940.64
37_A48_S1.3450.61
31_V119_S1.3350.60
129_G133_S1.3080.59
131_T134_S1.3000.58
11_G16_R1.2980.58
91_V115_Q1.2800.57
76_R94_G1.2650.56
43_I51_H1.2520.55
110_Y116_L1.2120.53
47_L78_M1.2010.52
12_E118_R1.1990.52
38_R114_F1.1930.52
109_H114_F1.1920.52
46_G84_F1.1780.51
64_E89_F1.1660.50
47_L111_L1.1540.49
110_Y113_E1.1390.48
10_E118_R1.1310.48
17_G113_E1.1080.46
130_A134_S1.0970.46
55_L83_E1.0750.44
114_F131_T1.0560.43
89_F102_V1.0550.43
26_M36_P1.0460.43
10_E138_P1.0300.42
17_G106_M1.0260.41
84_F137_V1.0010.40
76_R123_H0.9880.39
131_T136_F0.9780.38
55_L59_R0.9760.38
58_A75_L0.9750.38
44_T51_H0.9740.38
28_L36_P0.9660.38
38_R113_E0.9600.37
40_R113_E0.9560.37
31_V34_L0.9530.37
66_T71_I0.9530.37
101_E118_R0.9480.37
13_F54_V0.9420.36
40_R92_Y0.9390.36
118_R125_Q0.9340.36
37_A43_I0.9320.36
42_T51_H0.9290.36
43_I72_R0.9270.36
72_R119_S0.9210.35
103_Q107_I0.9190.35
90_A99_R0.9150.35
27_S30_D0.9090.35
85_V102_V0.9020.34
55_L78_M0.9010.34
34_L39_Q0.9010.34
129_G139_L0.8950.34
69_N103_Q0.8790.33
41_R45_R0.8780.33
62_G87_L0.8770.33
41_R76_R0.8500.31
128_I134_S0.8480.31
17_G108_G0.8470.31
50_E68_N0.8400.31
31_V89_F0.8310.30
68_N90_A0.8210.30
31_V110_Y0.8080.29
16_R76_R0.8030.29
70_P122_E0.8030.29
26_M30_D0.8000.29
22_E27_S0.8000.29
111_L119_S0.7970.29
60_E64_E0.7930.28
11_G42_T0.7930.28
70_P77_D0.7820.28
26_M107_I0.7790.28
75_L83_E0.7790.28
38_R41_R0.7780.28
79_P120_S0.7750.27
56_A89_F0.7720.27
44_T55_L0.7700.27
89_F100_V0.7700.27
69_N72_R0.7690.27
10_E125_Q0.7640.27
72_R79_P0.7620.27
93_T115_Q0.7560.26
130_A140_K0.7480.26
95_Q115_Q0.7380.26
8_G41_R0.7350.25
88_T100_V0.7290.25
29_E55_L0.7240.25
29_E69_N0.7200.25
44_T80_V0.7180.25
91_V111_L0.7150.25
84_F113_E0.7120.24
86_G101_E0.7120.24
70_P99_R0.7070.24
29_E39_Q0.7040.24
58_A120_S0.7030.24
130_A133_S0.6950.24
50_E62_G0.6940.24
75_L121_V0.6900.23
35_L52_H0.6850.23
15_Y40_R0.6810.23
11_G126_A0.6800.23
30_D90_A0.6780.23
71_I96_E0.6780.23
123_H127_G0.6740.23
66_T101_E0.6650.22
60_E78_M0.6630.22
71_I115_Q0.6620.22
96_E99_R0.6600.22
136_F139_L0.6550.22
91_V97_F0.6520.22
118_R135_K0.6500.22
92_Y115_Q0.6450.21
23_L48_S0.6430.21
37_A75_L0.6390.21
26_M105_E0.6350.21
135_K139_L0.6340.21
31_V36_P0.6290.21
69_N91_V0.6280.21
75_L126_A0.6270.21
25_E33_E0.6260.21
21_D54_V0.6240.21
89_F115_Q0.6180.20
60_E131_T0.6140.20
23_L107_I0.6140.20
12_E125_Q0.6130.20
46_G69_N0.6090.20
41_R108_G0.6070.20
38_R110_Y0.6060.20
80_V100_V0.6060.20
33_E53_K0.6030.20
58_A61_S0.6020.20
10_E18_H0.5940.19
71_I88_T0.5930.19
125_Q129_G0.5870.19
113_E121_V0.5780.19
46_G97_F0.5780.19
67_A71_I0.5770.19
80_V89_F0.5770.19
48_S92_Y0.5770.19
32_A44_T0.5760.19
70_P100_V0.5750.19
111_L116_L0.5670.18
10_E62_G0.5650.18
95_Q121_V0.5610.18
50_E55_L0.5610.18
28_L80_V0.5560.18
21_D57_E0.5520.18
66_T69_N0.5520.18
94_G108_G0.5520.18
17_G84_F0.5490.18
16_R85_V0.5470.18
12_E137_V0.5380.17
92_Y118_R0.5370.17
124_G127_G0.5350.17
59_R91_V0.5280.17
110_Y117_T0.5250.17
101_E114_F0.5250.17
22_E85_V0.5230.17
75_L110_Y0.5230.17
64_E81_L0.5180.17
20_L23_L0.5170.17
8_G85_V0.5160.17
52_H88_T0.5070.16
125_Q137_V0.5070.16
49_E53_K0.5060.16
21_D79_P0.5020.16
24_Q34_L0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4w23P 1 0.65 100 0.14 Contact Map
3j38P 1 0.8571 100 0.145 Contact Map
3zeyI 1 0.9286 100 0.161 Contact Map
3j7aX 1 0.6643 100 0.164 Contact Map
4ujpQ 1 0.8643 100 0.211 Contact Map
3j20T 1 0.7929 100 0.218 Contact Map
4bpeS 1 0.8286 100 0.229 Contact Map
3bbnS 1 0.6571 100 0.562 Contact Map
4kiyS 1 0.5643 100 0.575 Contact Map
3a1pB 1 0.6 100 0.579 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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