GREMLIN Database
RS3 - 30S ribosomal protein S3
UniProt: P15009 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 302 (237)
Sequences: 436 (287)
Seq/√Len: 18.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
31_G91_N7.2821.00
90_L125_A5.9571.00
12_L16_Q4.9151.00
95_V182_I3.3501.00
92_A163_D3.2160.99
89_D95_V2.8330.99
204_L207_D2.8060.98
205_V208_E2.7650.98
183_I186_N2.7270.98
29_G85_V2.7170.98
224_A227_E2.6510.98
100_A178_V2.4750.96
236_E239_S2.3240.95
108_Y116_T2.1950.93
207_D213_E2.0680.91
170_V175_T1.9550.88
227_E231_A1.9490.88
25_L30_Y1.8490.85
132_L143_V1.8310.84
232_D237_P1.7950.83
213_E217_E1.7900.83
86_E94_I1.7730.82
236_E241_P1.7550.82
89_D156_E1.7150.80
222_E227_E1.7020.80
54_V69_L1.6720.78
189_L193_F1.6670.78
225_D228_D1.6620.78
238_E242_A1.6420.77
211_A230_D1.6260.76
189_L192_D1.6030.75
21_F108_Y1.5910.75
23_E238_E1.5720.74
214_D219_L1.5640.73
217_E228_D1.5580.73
186_N199_A1.5560.73
221_G229_A1.5550.73
60_K82_V1.5520.73
213_E222_E1.5330.72
66_T80_I1.5320.72
202_E205_V1.5210.71
227_E230_D1.4960.70
190_P193_F1.4720.69
211_A215_L1.4680.69
19_E44_I1.4350.67
70_E95_V1.4120.65
133_S143_V1.3960.65
226_A231_A1.3820.64
192_D196_Q1.3760.63
237_P242_A1.3650.63
226_A234_A1.3540.62
79_Q85_V1.3510.62
115_T119_R1.3460.62
203_D206_V1.3360.61
6_E191_D1.3350.61
212_G215_L1.3260.60
214_D217_E1.3240.60
29_G57_K1.3200.60
70_E79_Q1.3190.60
58_G119_R1.3050.59
227_E232_D1.3030.59
233_A236_E1.2850.58
130_I176_I1.2750.57
8_I46_L1.2590.56
74_D117_I1.2440.55
113_G165_G1.2200.54
231_A235_A1.2200.54
206_V209_A1.2160.54
31_G73_F1.2150.54
147_N184_P1.2100.53
105_R167_G1.2070.53
117_I130_I1.1990.53
220_E228_D1.1990.53
232_D242_A1.1960.52
37_P179_N1.1860.52
130_I205_V1.1800.51
217_E222_E1.1760.51
23_E130_I1.1710.51
22_A93_Q1.1710.51
161_I191_D1.1700.51
202_E213_E1.1570.50
219_L227_E1.1550.50
20_F90_L1.1440.49
215_L223_D1.1430.49
235_A242_A1.1410.49
9_E125_A1.1370.49
222_E229_A1.1300.48
218_L222_E1.1270.48
220_E223_D1.1240.48
208_E222_E1.1210.48
240_E243_D1.1190.48
101_N178_V1.1110.47
93_Q166_K1.1110.47
37_P136_V1.1050.47
37_P169_A1.1010.46
221_G224_A1.0950.46
208_E239_S1.0930.46
29_G70_E1.0870.46
211_A227_E1.0840.45
35_L74_D1.0770.45
199_A206_V1.0760.45
235_A240_E1.0710.45
129_E153_H1.0700.45
137_T169_A1.0680.44
206_V243_D1.0670.44
230_D234_A1.0630.44
61_N64_K1.0610.44
239_S243_D1.0600.44
233_A237_P1.0590.44
32_G91_N1.0550.44
230_D237_P1.0530.43
26_A141_G1.0520.43
208_E214_D1.0500.43
5_L188_E1.0490.43
219_L232_D1.0490.43
108_Y137_T1.0410.43
233_A238_E1.0360.42
50_K119_R1.0350.42
223_D226_A1.0340.42
33_M156_E1.0310.42
236_E240_E1.0240.42
82_V88_P1.0140.41
153_H157_P1.0110.41
42_M145_K1.0060.41
39_P80_I0.9940.40
224_A232_D0.9930.40
223_D228_D0.9900.40
17_I65_I0.9900.40
81_D144_E0.9830.39
210_E237_P0.9790.39
220_E232_D0.9750.39
212_G219_L0.9740.39
219_L222_E0.9730.39
225_D229_A0.9720.39
210_E213_E0.9720.39
42_M137_T0.9650.38
226_A229_A0.9640.38
136_V171_M0.9630.38
153_H181_K0.9630.38
219_L240_E0.9620.38
17_I103_L0.9540.38
237_P241_P0.9530.37
159_E185_P0.9480.37
191_D195_I0.9460.37
217_E227_E0.9450.37
141_G165_G0.9370.37
13_Q171_M0.9250.36
90_L232_D0.9220.36
142_R178_V0.9210.36
220_E231_A0.9160.35
104_E123_S0.9080.35
65_I83_Q0.9030.35
216_E221_G0.9010.34
67_T71_E0.9000.34
217_E226_A0.8990.34
24_E68_Q0.8970.34
190_P196_Q0.8880.34
228_D234_A0.8870.34
28_A144_E0.8860.34
211_A229_A0.8770.33
5_L192_D0.8750.33
212_G217_E0.8650.32
202_E206_V0.8620.32
208_E211_A0.8610.32
229_A234_A0.8580.32
102_A150_Y0.8570.32
73_F79_Q0.8550.32
223_D232_D0.8550.32
37_P171_M0.8530.32
226_A230_D0.8480.32
212_G227_E0.8470.31
22_A182_I0.8460.31
44_I66_T0.8440.31
20_F24_E0.8410.31
216_E235_A0.8360.31
55_I84_E0.8320.31
213_E216_E0.8310.31
6_E9_E0.8290.31
108_Y130_I0.8290.31
218_L227_E0.8180.30
238_E241_P0.8150.30
29_G111_K0.8110.30
216_E225_D0.8100.30
55_I165_G0.8090.29
53_M79_Q0.8080.29
112_A144_E0.8050.29
200_D237_P0.8030.29
31_G79_Q0.7980.29
228_D232_D0.7970.29
215_L221_G0.7950.29
5_L191_D0.7920.29
99_L116_T0.7820.28
215_L219_L0.7820.28
226_A239_S0.7770.28
85_V107_W0.7760.28
235_A239_S0.7750.28
37_P157_P0.7720.28
161_I196_Q0.7720.28
122_E147_N0.7690.27
58_G65_I0.7690.27
215_L238_E0.7650.27
201_I204_L0.7650.27
206_V226_A0.7650.27
222_E228_D0.7640.27
126_L182_I0.7630.27
52_G84_E0.7610.27
108_Y111_K0.7570.27
29_G79_Q0.7550.27
217_E233_A0.7520.27
55_I59_G0.7510.27
203_D210_E0.7490.26
129_E145_K0.7470.26
29_G97_D0.7470.26
125_A190_P0.7450.26
90_L124_G0.7450.26
239_S242_A0.7390.26
117_I128_A0.7350.26
85_V101_N0.7320.26
222_E232_D0.7310.26
221_G225_D0.7270.25
60_K97_D0.7260.25
131_V137_T0.7260.25
46_L116_T0.7250.25
14_R181_K0.7240.25
30_Y99_L0.7230.25
92_A169_A0.7200.25
216_E226_A0.7190.25
223_D229_A0.7190.25
223_D227_E0.7160.25
48_A103_L0.7160.25
57_K111_K0.7150.25
193_F196_Q0.7150.25
37_P142_R0.7130.25
123_S190_P0.7080.24
62_I105_R0.7030.24
222_E230_D0.6990.24
23_E241_P0.6920.24
228_D237_P0.6900.24
53_M81_D0.6880.24
233_A242_A0.6870.24
218_L230_D0.6850.23
5_L8_I0.6830.23
212_G240_E0.6780.23
102_A183_I0.6750.23
207_D229_A0.6730.23
212_G226_A0.6700.23
33_M225_D0.6690.23
27_R80_I0.6660.23
123_S222_E0.6650.23
211_A223_D0.6620.22
150_Y183_I0.6620.22
63_R89_D0.6610.22
209_A212_G0.6610.22
62_I104_E0.6580.22
211_A236_E0.6570.22
221_G226_A0.6540.22
4_E125_A0.6530.22
138_G164_H0.6520.22
107_W113_G0.6510.22
45_V83_Q0.6510.22
73_F146_F0.6470.22
218_L224_A0.6460.22
107_W111_K0.6460.22
44_I62_I0.6430.22
207_D216_E0.6400.21
225_D235_A0.6400.21
113_G132_L0.6390.21
40_M80_I0.6350.21
213_E226_A0.6290.21
211_A231_A0.6290.21
30_Y48_A0.6280.21
106_G158_A0.6270.21
124_G215_L0.6270.21
31_G85_V0.6260.21
106_G140_R0.6260.21
202_E228_D0.6240.21
62_I130_I0.6220.21
189_L200_D0.6210.21
103_L122_E0.6190.21
210_E236_E0.6190.21
224_A230_D0.6180.21
12_L105_R0.6170.21
152_K185_P0.6150.20
194_E199_A0.6140.20
190_P194_E0.6120.20
38_T145_K0.6120.20
5_L186_N0.6110.20
195_I200_D0.6100.20
220_E224_A0.6100.20
221_G236_E0.6090.20
26_A175_T0.6090.20
161_I186_N0.6080.20
68_Q72_R0.6040.20
230_D243_D0.6030.20
125_A192_D0.6000.20
90_L130_I0.5990.20
187_A196_Q0.5990.20
234_A237_P0.5960.20
11_G141_G0.5960.20
110_R144_E0.5950.20
30_Y129_E0.5940.20
161_I189_L0.5930.20
130_I170_V0.5920.20
214_D218_L0.5910.19
99_L105_R0.5880.19
117_I148_R0.5860.19
6_E188_E0.5820.19
29_G145_K0.5790.19
234_A240_E0.5740.19
110_R145_K0.5740.19
38_T45_V0.5740.19
57_K88_P0.5700.19
196_Q199_A0.5670.19
203_D228_D0.5670.19
39_P45_V0.5670.19
194_E218_L0.5660.19
38_T43_Q0.5570.18
33_M72_R0.5560.18
50_K150_Y0.5520.18
225_D232_D0.5500.18
53_M138_G0.5440.18
137_T142_R0.5430.18
237_P243_D0.5410.18
214_D232_D0.5410.18
110_R137_T0.5390.18
79_Q141_G0.5390.18
39_P77_D0.5360.17
234_A242_A0.5360.17
228_D236_E0.5360.17
90_L243_D0.5350.17
93_Q165_G0.5340.17
221_G227_E0.5310.17
199_A225_D0.5310.17
207_D225_D0.5310.17
106_G172_K0.5300.17
203_D237_P0.5290.17
142_R181_K0.5270.17
5_L46_L0.5260.17
137_T178_V0.5240.17
36_A171_M0.5220.17
229_A233_A0.5220.17
16_Q19_E0.5210.17
14_R138_G0.5150.17
104_E188_E0.5150.17
99_L122_E0.5150.17
227_E235_A0.5130.17
55_I100_A0.5130.17
208_E237_P0.5110.17
223_D234_A0.5110.17
68_Q71_E0.5090.16
207_D238_E0.5060.16
218_L221_G0.5050.16
136_V184_P0.5040.16
50_K102_A0.5040.16
232_D243_D0.5020.16
232_D238_E0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j20C 1 0.6159 100 0.321 Contact Map
3zeyX 1 0.649 100 0.321 Contact Map
4w23D 1 0.702 100 0.33 Contact Map
3j7aD 1 0.5132 100 0.335 Contact Map
4bpeC 1 0.6987 100 0.336 Contact Map
4ujpE 1 0.702 100 0.34 Contact Map
4rb5C 1 0.6093 100 0.359 Contact Map
4kiyC 1 0.6093 100 0.368 Contact Map
4tp8C 1 0.6093 100 0.371 Contact Map
3bbnC 1 0.6093 100 0.389 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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