RL10 - HALSA - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

RL10 - 50S ribosomal protein L10

UniProt:	P13553	Sequences: MSAEEQRTTEEVPEWKRQEVAELVDLLETYDSVGVVNVTGIPSKQLQDMRRGLHGQAALRMSRNTLLVRALEEAGDGLDTLTEYVEGEVGLVATNDNPFGLYQQLENSKTPAPINAGEVAPNDIVVPEGDTGIDPGPFVGELQTIGANARIQEGSIQVLDDSVVTEEGETVSDDVSNVLSELGIEPKEVGLDLRGVFSEGVLFTPEELEIDVDEYRADIQSAAASARNLSVNAAYPTERTAPDLIAKGRGEAKSLGLQASVESPDLADDLVSKADAQVRALAAQIDDEDALPEELQDVDAPAAPAGGEADTTADEQSDETQASEADDADDSDDDDDDDDGNAGAEGLGEMFG	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	352 (298)
Sequences:	563 (346)
Seq/√Len:	20.0

HALSA - RL10
SULSO - RL10

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
256_G	266_L	4.932	1.00
128_E	161_D	4.921	1.00
307_G	310_D	4.081	1.00
130_D	155_S	3.736	1.00
56_Q	104_Q	3.568	1.00
31_D	95_N	3.383	1.00
172_S	175_V	3.294	1.00
302_A	306_G	3.210	1.00
14_E	18_Q	3.156	1.00
87_G	94_T	3.110	0.99
26_L	58_A	3.055	0.99
298_V	301_P	3.043	0.99
274_A	278_V	2.932	0.99
299_D	303_A	2.742	0.99
127_P	161_D	2.669	0.98
119_V	170_T	2.573	0.98
262_E	267_A	2.553	0.98
38_V	61_M	2.542	0.98
271_V	278_V	2.541	0.98
123_D	167_E	2.464	0.97
306_G	309_A	2.404	0.97
137_P	181_E	2.357	0.96
283_A	286_D	2.279	0.95
292_P	295_L	2.016	0.91
71_L	75_G	2.014	0.91
25_D	29_T	1.997	0.91
34_G	193_L	1.938	0.89
272_S	279_R	1.931	0.89
268_D	272_S	1.903	0.89
126_V	161_D	1.903	0.89
84_Y	195_G	1.806	0.86
95_N	222_A	1.798	0.85
300_A	303_A	1.771	0.85
253_K	269_D	1.743	0.84
299_D	302_A	1.726	0.83
302_A	309_A	1.724	0.83
297_D	301_P	1.708	0.82
256_G	262_E	1.706	0.82
305_A	309_A	1.676	0.81
256_G	261_V	1.653	0.80
303_A	307_G	1.643	0.80
13_P	229_L	1.601	0.78
266_L	269_D	1.589	0.77
216_R	220_Q	1.583	0.77
232_N	258_Q	1.564	0.76
142_L	149_A	1.557	0.76
284_Q	287_D	1.555	0.76
163_V	166_E	1.551	0.76
21_A	25_D	1.543	0.75
42_P	222_A	1.528	0.74
166_E	169_E	1.527	0.74
292_P	296_Q	1.519	0.74
44_K	48_D	1.509	0.74
305_A	308_E	1.502	0.73
13_P	17_R	1.502	0.73
27_L	59_L	1.480	0.72
271_V	275_D	1.449	0.70
226_A	229_L	1.437	0.70
304_P	307_G	1.435	0.70
88_E	143_Q	1.435	0.70
242_P	245_I	1.434	0.70
230_S	238_E	1.432	0.69
125_V	163_V	1.430	0.69
294_E	302_A	1.423	0.69
265_D	268_D	1.423	0.69
43_S	171_V	1.423	0.69
33_V	129_G	1.422	0.69
303_A	309_A	1.420	0.69
125_V	161_D	1.413	0.68
298_V	309_A	1.403	0.68
17_R	233_A	1.402	0.68
210_I	256_G	1.396	0.67
160_D	249_R	1.396	0.67
93_A	147_A	1.370	0.66
291_L	295_L	1.368	0.66
18_Q	21_A	1.351	0.65
228_N	232_N	1.345	0.64
293_E	296_Q	1.328	0.63
114_I	171_V	1.316	0.63
281_L	285_I	1.308	0.62
147_A	158_V	1.307	0.62
205_P	254_S	1.306	0.62
41_I	45_Q	1.289	0.61
291_L	298_V	1.289	0.61
302_A	305_A	1.288	0.61
47_Q	201_V	1.280	0.61
46_L	92_V	1.276	0.60
30_Y	58_A	1.269	0.60
255_L	258_Q	1.260	0.59
51_R	248_G	1.259	0.59
144_T	174_D	1.256	0.59
271_V	279_R	1.253	0.59
81_L	246_A	1.251	0.59
263_S	266_L	1.227	0.57
298_V	302_A	1.224	0.57
275_D	279_R	1.223	0.57
306_G	310_D	1.219	0.57
163_V	168_G	1.208	0.56
206_E	212_V	1.205	0.56
70_A	137_P	1.204	0.56
289_D	292_P	1.204	0.56
115_N	206_E	1.194	0.55
214_E	217_A	1.191	0.55
301_P	305_A	1.186	0.55
18_Q	213_D	1.176	0.54
288_E	299_D	1.173	0.54
298_V	303_A	1.168	0.53
193_L	224_A	1.159	0.53
122_N	167_E	1.156	0.53
302_A	308_E	1.153	0.52
300_A	306_G	1.152	0.52
147_A	162_S	1.147	0.52
56_Q	96_D	1.138	0.51
128_E	210_I	1.134	0.51
219_I	223_A	1.131	0.51
286_D	292_P	1.123	0.51
300_A	304_P	1.116	0.50
245_I	290_A	1.110	0.50
253_K	257_L	1.109	0.50
139_V	149_A	1.107	0.49
87_G	203_F	1.102	0.49
129_G	136_G	1.102	0.49
112_A	143_Q	1.096	0.49
90_G	157_Q	1.087	0.48
293_E	299_D	1.077	0.48
59_L	72_E	1.069	0.47
45_Q	112_A	1.067	0.47
19_E	62_S	1.060	0.46
70_A	180_S	1.059	0.46
249_R	252_A	1.052	0.46
150_R	159_L	1.049	0.46
108_S	156_I	1.043	0.45
155_S	181_E	1.038	0.45
291_L	294_E	1.038	0.45
22_E	83_E	1.038	0.45
224_A	301_P	1.032	0.45
38_V	46_L	1.032	0.45
165_T	169_E	1.029	0.44
63_R	189_V	1.027	0.44
38_V	67_L	1.019	0.44
36_V	92_V	1.019	0.44
123_D	169_E	1.013	0.43
240_T	244_L	1.007	0.43
14_E	168_G	1.005	0.43
102_Y	209_E	0.995	0.42
103_Q	107_N	0.991	0.42
14_E	84_Y	0.979	0.41
96_D	298_V	0.976	0.41
94_T	155_S	0.975	0.41
287_D	291_L	0.975	0.41
76_D	79_D	0.969	0.41
111_P	155_S	0.963	0.40
25_D	217_A	0.963	0.40
126_V	305_A	0.963	0.40
252_A	255_L	0.957	0.40
81_L	203_F	0.952	0.40
242_P	266_L	0.949	0.39
123_D	165_T	0.945	0.39
160_D	197_F	0.934	0.38
165_T	211_D	0.932	0.38
260_S	270_L	0.925	0.38
33_V	59_L	0.923	0.38
173_D	206_E	0.922	0.38
251_E	268_D	0.922	0.38
44_K	47_Q	0.921	0.38
136_G	146_G	0.917	0.37
143_Q	151_I	0.916	0.37
219_I	222_A	0.912	0.37
36_V	90_G	0.911	0.37
17_R	21_A	0.908	0.37
45_Q	156_I	0.908	0.37
218_D	274_A	0.907	0.37
271_V	274_A	0.903	0.37
197_F	214_E	0.901	0.36
214_E	218_D	0.901	0.36
19_E	23_L	0.900	0.36
216_R	223_A	0.898	0.36
170_T	198_S	0.897	0.36
246_A	264_P	0.895	0.36
299_D	306_G	0.887	0.36
164_V	170_T	0.877	0.35
19_E	189_V	0.872	0.35
85_V	92_V	0.870	0.35
84_Y	202_L	0.867	0.34
191_L	211_D	0.864	0.34
94_T	130_D	0.860	0.34
89_V	156_I	0.854	0.34
161_D	267_A	0.849	0.33
92_V	144_T	0.846	0.33
89_V	194_R	0.846	0.33
301_P	304_P	0.844	0.33
185_E	203_F	0.843	0.33
296_Q	300_A	0.840	0.33
25_D	115_N	0.837	0.33
80_T	83_E	0.834	0.33
63_R	149_A	0.832	0.32
171_V	236_P	0.832	0.32
45_Q	200_G	0.829	0.32
296_Q	301_P	0.825	0.32
92_V	246_A	0.825	0.32
53_L	133_I	0.825	0.32
137_P	152_Q	0.825	0.32
303_A	308_E	0.824	0.32
64_N	236_P	0.821	0.32
248_G	297_D	0.821	0.32
105_L	189_V	0.817	0.32
72_E	308_E	0.817	0.32
217_A	221_S	0.815	0.31
12_V	15_W	0.815	0.31
290_A	293_E	0.812	0.31
275_D	278_V	0.809	0.31
156_I	161_D	0.809	0.31
295_L	303_A	0.809	0.31
281_L	295_L	0.808	0.31
13_P	75_G	0.804	0.31
126_V	206_E	0.804	0.31
123_D	148_N	0.802	0.31
35_V	158_V	0.801	0.31
13_P	164_V	0.799	0.31
202_L	301_P	0.796	0.30
95_N	159_L	0.795	0.30
256_G	265_D	0.794	0.30
69_R	205_P	0.794	0.30
13_P	283_A	0.792	0.30
27_L	35_V	0.792	0.30
287_D	297_D	0.784	0.30
159_L	241_A	0.783	0.30
41_I	71_L	0.779	0.29
81_L	190_G	0.778	0.29
41_I	110_T	0.777	0.29
126_V	302_A	0.775	0.29
271_V	277_Q	0.772	0.29
302_A	307_G	0.771	0.29
245_I	252_A	0.771	0.29
154_G	186_P	0.770	0.29
47_Q	134_D	0.768	0.29
136_G	165_T	0.768	0.29
81_L	229_L	0.767	0.29
40_G	118_E	0.766	0.29
85_V	165_T	0.764	0.29
245_I	293_E	0.764	0.29
257_L	261_V	0.763	0.29
76_D	80_T	0.760	0.28
145_I	157_Q	0.758	0.28
29_T	167_E	0.758	0.28
69_R	159_L	0.757	0.28
286_D	299_D	0.753	0.28
69_R	146_G	0.751	0.28
64_N	191_L	0.750	0.28
199_E	212_V	0.749	0.28
295_L	301_P	0.746	0.28
99_F	103_Q	0.743	0.28
285_I	289_D	0.741	0.27
127_P	130_D	0.740	0.27
113_P	272_S	0.736	0.27
26_L	30_Y	0.734	0.27
303_A	310_D	0.732	0.27
14_E	17_R	0.732	0.27
226_A	239_R	0.732	0.27
24_V	191_L	0.731	0.27
35_V	85_V	0.731	0.27
290_A	295_L	0.729	0.27
111_P	185_E	0.729	0.27
26_L	93_A	0.728	0.27
230_S	255_L	0.728	0.27
300_A	305_A	0.727	0.27
83_E	219_I	0.725	0.27
301_P	307_G	0.724	0.27
96_D	101_L	0.724	0.27
258_Q	264_P	0.724	0.27
255_L	301_P	0.723	0.27
276_A	279_R	0.721	0.26
121_P	142_L	0.719	0.26
247_K	251_E	0.717	0.26
38_V	91_L	0.714	0.26
282_A	290_A	0.714	0.26
15_W	42_P	0.713	0.26
164_V	266_L	0.709	0.26
15_W	248_G	0.708	0.26
250_G	254_S	0.708	0.26
124_I	205_P	0.707	0.26
48_D	51_R	0.707	0.26
293_E	297_D	0.707	0.26
32_S	136_G	0.706	0.26
140_G	149_A	0.706	0.26
65_T	205_P	0.705	0.26
297_D	300_A	0.704	0.26
164_V	175_V	0.703	0.26
254_S	258_Q	0.699	0.25
30_Y	79_D	0.698	0.25
48_D	52_G	0.697	0.25
245_I	310_D	0.694	0.25
240_T	243_D	0.693	0.25
262_E	266_L	0.693	0.25
174_D	254_S	0.692	0.25
24_V	257_L	0.692	0.25
80_T	256_G	0.691	0.25
294_E	303_A	0.691	0.25
282_A	286_D	0.689	0.25
33_V	74_A	0.686	0.25
305_A	310_D	0.686	0.25
253_K	266_L	0.686	0.25
49_M	197_F	0.686	0.25
249_R	253_K	0.685	0.25
304_P	309_A	0.683	0.25
265_D	310_D	0.683	0.25
249_R	265_D	0.681	0.24
31_D	217_A	0.677	0.24
99_F	123_D	0.676	0.24
101_L	106_E	0.676	0.24
37_N	192_D	0.675	0.24
38_V	199_E	0.673	0.24
25_D	164_V	0.672	0.24
45_Q	143_Q	0.671	0.24
26_L	244_L	0.670	0.24
37_N	246_A	0.670	0.24
301_P	306_G	0.669	0.24
113_P	190_G	0.668	0.24
144_T	171_V	0.667	0.24
44_K	147_A	0.667	0.24
79_D	91_L	0.663	0.24
15_W	18_Q	0.661	0.24
59_L	257_L	0.660	0.23
293_E	298_V	0.660	0.23
124_I	261_V	0.659	0.23
41_I	153_E	0.659	0.23
15_W	70_A	0.658	0.23
72_E	76_D	0.655	0.23
273_K	277_Q	0.655	0.23
119_V	205_P	0.655	0.23
168_G	219_I	0.654	0.23
288_E	291_L	0.653	0.23
290_A	294_E	0.652	0.23
95_N	203_F	0.651	0.23
70_A	148_N	0.647	0.23
132_G	161_D	0.646	0.23
43_S	162_S	0.644	0.23
132_G	155_S	0.643	0.23
59_L	95_N	0.643	0.23
28_E	204_T	0.642	0.23
199_E	297_D	0.639	0.23
290_A	305_A	0.638	0.22
153_E	213_D	0.636	0.22
28_E	196_V	0.635	0.22
41_I	143_Q	0.634	0.22
149_A	178_V	0.632	0.22
295_L	298_V	0.629	0.22
98_P	242_P	0.628	0.22
27_L	254_S	0.627	0.22
294_E	297_D	0.624	0.22
19_E	41_I	0.621	0.22
133_I	183_G	0.620	0.22
143_Q	209_E	0.619	0.22
147_A	150_R	0.616	0.21
162_S	263_S	0.616	0.21
24_V	37_N	0.615	0.21
107_N	290_A	0.615	0.21
62_S	187_K	0.612	0.21
41_I	189_V	0.610	0.21
145_I	172_S	0.608	0.21
129_G	161_D	0.606	0.21
299_D	305_A	0.606	0.21
85_V	107_N	0.602	0.21
61_M	141_E	0.601	0.21
134_D	148_N	0.601	0.21
294_E	310_D	0.601	0.21
59_L	92_V	0.600	0.21
41_I	144_T	0.599	0.21
63_R	86_E	0.599	0.21
56_Q	101_L	0.597	0.21
225_S	246_A	0.597	0.21
226_A	255_L	0.596	0.21
272_S	277_Q	0.591	0.20
139_V	143_Q	0.590	0.20
274_A	277_Q	0.588	0.20
85_V	257_L	0.586	0.20
20_V	66_L	0.583	0.20
35_V	223_A	0.582	0.20
75_G	202_L	0.582	0.20
194_R	246_A	0.581	0.20
252_A	274_A	0.580	0.20
136_G	248_G	0.580	0.20
67_L	169_E	0.579	0.20
170_T	226_A	0.577	0.20
66_L	182_L	0.574	0.20
106_E	173_D	0.574	0.20
72_E	213_D	0.573	0.20
55_G	58_A	0.571	0.20
122_N	128_E	0.570	0.20
141_E	145_I	0.569	0.20
96_D	245_I	0.569	0.20
19_E	60_R	0.567	0.19
251_E	259_A	0.567	0.19
70_A	76_D	0.567	0.19
283_A	294_E	0.566	0.19
116_A	137_P	0.562	0.19
113_P	196_V	0.562	0.19
65_T	190_G	0.559	0.19
161_D	164_V	0.558	0.19
25_D	95_N	0.558	0.19
15_W	105_L	0.558	0.19
227_R	243_D	0.558	0.19
258_Q	271_V	0.557	0.19
146_G	222_A	0.556	0.19
59_L	90_G	0.555	0.19
20_V	156_I	0.553	0.19
212_V	216_R	0.551	0.19
125_V	290_A	0.547	0.19
203_F	220_Q	0.546	0.19
31_D	180_S	0.546	0.19
98_P	172_S	0.545	0.19
270_L	279_R	0.545	0.19
199_E	202_L	0.545	0.19
101_L	201_V	0.543	0.18
105_L	204_T	0.543	0.18
69_R	114_I	0.540	0.18
34_G	105_L	0.539	0.18
33_V	136_G	0.537	0.18
169_E	242_P	0.536	0.18
109_K	190_G	0.536	0.18
78_L	249_R	0.536	0.18
302_A	310_D	0.535	0.18
26_L	219_I	0.533	0.18
15_W	137_P	0.530	0.18
53_L	217_A	0.528	0.18
65_T	200_G	0.528	0.18
256_G	259_A	0.526	0.18
299_D	304_P	0.526	0.18
191_L	235_Y	0.525	0.18
299_D	310_D	0.523	0.18
132_G	139_V	0.522	0.18
115_N	208_L	0.522	0.18
30_Y	93_A	0.518	0.18
59_L	194_R	0.515	0.17
57_A	146_G	0.515	0.17
78_L	202_L	0.513	0.17
280_A	283_A	0.511	0.17
17_R	69_R	0.510	0.17
15_W	261_V	0.510	0.17
289_D	300_A	0.508	0.17
113_P	132_G	0.507	0.17
62_S	88_E	0.506	0.17
103_Q	160_D	0.504	0.17
243_D	250_G	0.504	0.17
167_E	206_E	0.501	0.17
143_Q	190_G	0.501	0.17
72_E	214_E	0.500	0.17

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1vq8G	1	0.0028	100	0.219	Contact Map
3j21k	1	0.5852	100	0.25	Contact Map
3j3bq	1	0.7869	100	0.285	Contact Map
3j61q	1	0.7301	100	0.292	Contact Map
4ujti	1	0.3977	100	0.293	Contact Map
3a1yG	1	0.5824	100	0.314	Contact Map
4hubG	1	0.5852	100	0.388	Contact Map
3jsyA	1	0.5909	100	0.463	Contact Map
4w22q	1	0.5653	100	0.482	Contact Map
3j65n	1	0.5994	100	0.534	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0122 seconds.