GREMLIN Database
FLAB3 - Flagellin B3
UniProt: P13078 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 193 (180)
Sequences: 307 (227)
Seq/√Len: 16.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
54_A57_Q4.5711.00
181_V185_L4.3191.00
70_N77_D3.9661.00
42_Y54_A3.2670.99
148_M163_V2.7040.97
72_N77_D2.5840.96
11_R34_G2.3950.94
163_V179_A2.2170.92
46_K59_S2.1950.91
21_V98_T2.0720.88
12_G38_N2.0710.88
116_S119_S2.0230.87
131_G142_D1.9820.86
11_R14_V1.9670.86
16_I22_F1.9650.86
12_G28_V1.9360.85
61_R86_A1.9330.85
12_G21_V1.8850.83
165_L177_Y1.8630.82
14_V68_Y1.8480.82
14_V21_V1.8380.81
149_Y152_G1.7960.80
18_T32_A1.7940.80
79_V148_M1.7590.78
25_M87_A1.7100.76
34_G160_G1.7050.76
25_M36_L1.6750.75
57_Q63_N1.6480.73
34_G40_A1.6090.72
14_V48_S1.6050.71
86_A169_T1.5990.71
113_S122_E1.5540.69
15_G19_L1.5100.67
36_L50_T1.5050.66
19_L30_A1.5000.66
160_G170_Q1.4960.66
79_V104_P1.4910.66
75_K187_D1.4820.65
101_W157_L1.4360.63
22_F28_V1.4330.62
36_L40_A1.4250.62
110_L148_M1.4170.62
139_E160_G1.3940.60
62_I96_K1.3550.58
112_Y136_V1.3460.57
22_F26_V1.3240.56
40_A82_T1.3070.55
169_T181_V1.3060.55
64_I110_L1.3060.55
16_I24_A1.2990.55
83_V114_S1.2970.55
143_R181_V1.2900.54
20_I24_A1.2790.53
108_T153_V1.2720.53
20_I23_I1.2670.53
31_I46_K1.2630.53
73_S121_G1.2570.52
55_S59_S1.2560.52
102_I163_V1.2520.52
64_I177_Y1.2460.52
52_E56_A1.2410.51
61_R175_T1.2380.51
79_V101_W1.2310.51
57_Q169_T1.2040.49
12_G42_Y1.1990.49
12_G130_K1.1980.49
31_I40_A1.1970.49
49_A178_W1.1960.49
38_N42_Y1.1830.48
99_I144_I1.1830.48
85_Q89_A1.1800.48
59_S175_T1.1790.48
113_S149_Y1.1670.47
42_Y57_Q1.1580.46
26_V41_G1.1540.46
27_L41_G1.1440.45
14_V34_G1.1410.45
76_V129_I1.1340.45
46_K55_S1.1310.45
12_G22_F1.1220.44
81_L148_M1.1200.44
120_L151_S1.1170.44
85_Q165_L1.1080.43
54_A63_N1.0840.42
167_V177_Y1.0790.42
42_Y52_E1.0760.41
21_V36_L1.0740.41
28_V53_E1.0560.40
92_I168_T1.0410.39
115_N120_L1.0360.39
15_G22_F1.0330.39
161_E185_L1.0240.39
40_A49_A1.0150.38
9_D52_E1.0030.37
65_V143_R0.9910.37
177_Y180_H0.9790.36
12_G53_E0.9770.36
101_W163_V0.9590.35
11_R52_E0.9490.34
164_Q168_T0.9480.34
26_V39_T0.9460.34
118_S151_S0.9460.34
49_A63_N0.9420.34
169_T185_L0.9340.34
125_T147_I0.9330.34
114_S155_S0.9320.33
21_V42_Y0.9310.33
18_T26_V0.9240.33
35_V40_A0.9160.33
95_T188_K0.9100.32
15_G18_T0.9070.32
141_S146_V0.9040.32
73_S188_K0.8880.31
45_S176_T0.8830.31
18_T30_A0.8800.31
12_G26_V0.8770.31
18_T38_N0.8770.31
77_D114_S0.8740.30
14_V18_T0.8720.30
60_N139_E0.8710.30
64_I151_S0.8710.30
41_G50_T0.8630.30
82_T85_Q0.8600.30
34_G48_S0.8520.29
42_Y64_I0.8460.29
79_V116_S0.8440.29
26_V53_E0.8430.29
103_G150_A0.8410.29
106_K167_V0.8330.28
9_D49_A0.8260.28
41_G173_S0.8240.28
61_R169_T0.8240.28
171_Y174_K0.8220.28
126_T139_E0.8210.28
113_S156_T0.8140.28
133_N142_D0.8100.27
71_V79_V0.8070.27
55_S61_R0.8060.27
40_A185_L0.8030.27
127_E147_I0.8020.27
165_L179_A0.8010.27
26_V55_S0.8000.27
42_Y185_L0.7980.27
14_V164_Q0.7950.27
42_Y63_N0.7940.27
161_E181_V0.7930.27
8_E89_A0.7870.26
46_K64_I0.7800.26
48_S57_Q0.7790.26
55_S169_T0.7790.26
49_A55_S0.7750.26
116_S121_G0.7740.26
110_L166_T0.7720.26
84_R180_H0.7700.25
26_V38_N0.7700.25
56_A97_S0.7680.25
45_S60_N0.7590.25
24_A33_A0.7550.25
46_K50_T0.7490.25
19_L22_F0.7420.24
105_D158_G0.7390.24
120_L149_Y0.7340.24
102_I136_V0.7330.24
14_V145_K0.7300.24
16_I21_V0.7230.23
128_S133_N0.7220.23
31_I185_L0.7220.23
112_Y124_F0.7180.23
25_M32_A0.7180.23
120_L148_M0.7170.23
34_G46_K0.7160.23
71_V77_D0.7140.23
122_E187_D0.7140.23
98_T163_V0.7070.23
57_Q68_Y0.7040.23
21_V54_A0.7030.23
20_I88_G0.7020.23
14_V66_S0.7020.23
83_V168_T0.7010.22
104_P136_V0.7010.22
76_V134_A0.7010.22
45_S90_D0.6960.22
39_T43_L0.6910.22
132_N160_G0.6870.22
71_V155_S0.6830.22
108_T113_S0.6820.22
81_L101_W0.6800.22
93_N170_Q0.6780.22
73_S77_D0.6710.21
141_S169_T0.6660.21
24_A35_V0.6650.21
120_L123_N0.6610.21
40_A51_G0.6580.21
42_Y46_K0.6570.21
79_V156_T0.6560.21
122_E167_V0.6550.21
86_A165_L0.6550.21
123_N152_G0.6520.21
11_R38_N0.6500.20
126_T130_K0.6480.20
110_L168_T0.6480.20
62_I168_T0.6390.20
41_G55_S0.6380.20
42_Y61_R0.6310.20
115_N147_I0.6270.20
86_A146_V0.6250.19
172_G182_P0.6250.19
131_G146_V0.6230.19
115_N121_G0.6210.19
116_S156_T0.6190.19
38_N54_A0.6150.19
85_Q176_T0.6140.19
17_G20_I0.6070.19
27_L53_E0.6040.19
76_V79_V0.6030.19
55_S170_Q0.6020.19
81_L167_V0.6020.19
19_L43_L0.6000.19
64_I109_T0.5980.18
94_L98_T0.5960.18
49_A59_S0.5930.18
31_I52_E0.5920.18
9_D42_Y0.5920.18
99_I148_M0.5880.18
87_A184_S0.5870.18
34_G49_A0.5820.18
21_V39_T0.5800.18
16_I26_V0.5800.18
29_A32_A0.5790.18
100_Q176_T0.5780.18
83_V115_N0.5730.18
129_I133_N0.5730.18
42_Y67_A0.5720.18
114_S134_A0.5720.18
17_G22_F0.5710.18
75_K188_K0.5690.17
56_A140_Q0.5690.17
165_L175_T0.5680.17
137_L164_Q0.5670.17
46_K54_A0.5650.17
25_M180_H0.5640.17
53_E57_Q0.5590.17
18_T41_G0.5550.17
115_N118_S0.5530.17
35_V38_N0.5510.17
129_I143_R0.5500.17
68_Y187_D0.5430.17
125_T128_S0.5410.17
22_F43_L0.5380.16
21_V87_A0.5380.16
52_E102_I0.5370.16
93_N140_Q0.5280.16
42_Y49_A0.5260.16
124_F147_I0.5250.16
12_G23_I0.5240.16
22_F58_V0.5240.16
99_I171_Y0.5230.16
45_S61_R0.5210.16
56_A112_Y0.5150.16
60_N163_V0.5140.16
177_Y186_K0.5130.16
149_Y158_G0.5130.16
95_T134_A0.5100.16
137_L162_E0.5080.15
55_S178_W0.5070.15
133_N138_V0.5070.15
16_I20_I0.5030.15
68_Y103_G0.5010.15
64_I91_N0.5000.15
113_S151_S0.5000.15
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ncxA 1 0.5337 9.2 0.961 Contact Map
2l8aA 1 0.6425 7.5 0.963 Contact Map
2kxtA 1 0.544 6 0.964 Contact Map
2ra1A 1 0.9378 5.6 0.965 Contact Map
3ibzA 1 0.544 5.5 0.965 Contact Map
2xbtA 1 0.6736 4.7 0.966 Contact Map
4ue3S 2 0.0311 4.3 0.967 Contact Map
2zy9A 2 0.3679 3.9 0.968 Contact Map
4b9fA 1 0.6632 3.4 0.969 Contact Map
2bpsA 1 0.1813 3.4 0.969 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0076 seconds.