GREMLIN Database
HTR4 - Transducer protein Htr4
UniProt: P0DMI4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 778 (659)
Sequences: 958 (868)
Seq/√Len: 33.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
427_A432_D6.4011.00
333_A338_E5.6951.00
347_R352_G4.4691.00
731_E735_D4.1171.00
26_K349_D3.2881.00
608_N630_D3.2251.00
555_A678_E3.1931.00
530_V702_M3.1911.00
331_A354_L2.9911.00
339_Y366_Q2.9091.00
606_N624_V2.9081.00
626_D630_D2.7751.00
377_V380_E2.7461.00
601_N610_E2.6871.00
615_D618_G2.6511.00
557_D676_E2.6421.00
614_A618_G2.6271.00
331_A361_L2.5951.00
376_Q379_A2.5421.00
359_A362_R2.5251.00
598_E609_I2.4941.00
84_R87_A2.4110.99
608_N634_E2.4020.99
589_I646_V2.4010.99
728_T735_D2.3920.99
23_Y320_T2.3880.99
583_M589_I2.3510.99
354_L361_L2.3060.99
331_A358_F2.2940.99
672_E676_E2.2830.99
516_V715_A2.2600.99
460_M691_A2.2200.99
630_D637_A2.1870.99
618_G622_A2.1820.99
531_A534_A2.1800.99
372_A375_Q2.1720.99
447_A450_A2.1620.99
500_G738_A2.1340.99
437_L449_I2.1330.99
599_Q610_E2.1310.99
207_T210_S2.0980.99
620_G627_E2.0880.99
361_L365_V2.0820.98
349_D352_G2.0720.98
667_V671_V2.0670.98
436_R458_A2.0600.98
506_A730_A2.0490.98
153_L187_R2.0480.98
477_A541_S2.0410.98
598_E636_K2.0390.98
728_T732_S2.0020.98
354_L365_V2.0020.98
594_T598_E1.9970.98
747_V754_L1.9960.98
437_L450_A1.9870.98
379_A383_R1.9810.98
612_A623_V1.9730.98
441_V450_A1.9700.98
327_L358_F1.9630.98
602_M612_A1.9380.98
374_E378_D1.9250.97
538_A699_S1.9220.97
327_L343_L1.9220.97
165_P168_N1.9180.97
370_R374_E1.9170.97
605_L622_A1.9120.97
75_W79_R1.9090.97
677_T681_L1.9000.97
728_T731_E1.8940.97
605_L629_K1.8790.97
436_R461_E1.8730.97
592_A727_A1.8700.97
317_G321_V1.8610.97
579_L663_I1.8570.97
219_G224_D1.8490.97
667_V670_G1.8490.97
690_E693_T1.8480.97
622_A627_E1.8480.97
354_L358_F1.8230.96
317_G320_T1.8190.96
708_S715_A1.8150.96
594_T643_E1.8140.96
334_L365_V1.8100.96
27_F320_T1.8080.96
602_M681_L1.8020.96
548_G552_Q1.7960.96
589_I645_L1.7950.96
378_D381_A1.7920.96
211_F224_D1.7670.96
422_S425_M1.7660.96
579_L639_A1.7490.95
604_A613_R1.7450.95
506_A729_E1.7360.95
524_S713_T1.7260.95
608_N626_D1.7140.95
276_W279_T1.7100.95
499_V737_A1.7100.95
517_A716_V1.7080.95
589_I670_G1.7080.95
583_M754_L1.6910.95
582_K666_R1.6860.94
681_L684_I1.6840.94
375_Q379_A1.6830.94
597_A622_A1.6820.94
598_E726_T1.6640.94
579_L670_G1.6620.94
646_V670_G1.6580.94
578_D581_A1.6570.94
166_Y196_L1.6550.94
551_G608_N1.6490.94
629_K740_Q1.6490.94
630_D633_D1.6370.94
595_D626_D1.6350.93
424_T453_F1.6320.93
612_A622_A1.6290.93
545_A549_D1.6250.93
421_F450_A1.6240.93
599_Q605_L1.6180.93
440_D447_A1.6170.93
609_I726_T1.6040.93
605_L612_A1.5950.93
166_Y193_T1.5950.93
447_A451_A1.5880.92
598_E633_D1.5810.92
353_R356_E1.5780.92
471_A474_V1.5760.92
209_H286_E1.5700.92
418_A446_M1.5640.92
594_T609_I1.5640.92
450_A456_M1.5530.92
440_D450_A1.5520.92
597_A614_A1.5500.92
509_Q730_A1.5490.91
533_S694_G1.5450.91
561_Q590_V1.5420.91
342_D359_A1.5420.91
623_V627_E1.5390.91
626_D643_E1.5350.91
729_E740_Q1.5340.91
593_I670_G1.5330.91
726_T729_E1.5300.91
418_A421_F1.5230.91
324_L354_L1.5210.91
73_D76_H1.5210.91
82_N115_V1.5200.91
505_R722_L1.5160.91
585_E648_E1.5150.91
334_L361_L1.5130.90
643_E730_A1.5060.90
593_I627_E1.4960.90
145_A148_W1.4930.90
433_L446_M1.4920.90
498_A729_E1.4900.90
128_V131_S1.4880.90
677_T719_V1.4870.90
334_L362_R1.4860.90
646_V663_I1.4860.90
583_M673_T1.4850.90
355_F361_L1.4820.90
436_R454_N1.4810.90
590_V694_G1.4740.89
579_L598_E1.4660.89
122_S125_D1.4620.89
579_L609_I1.4610.89
681_L698_I1.4550.89
626_D636_K1.4550.89
327_L354_L1.4490.88
97_A101_Q1.4430.88
454_N460_M1.4370.88
548_G684_I1.4300.88
633_D730_A1.4270.88
509_Q722_L1.4230.88
592_A642_I1.4060.87
618_G623_V1.4020.87
418_A450_A1.3940.86
437_L446_M1.3910.86
589_I592_A1.3810.86
559_V706_A1.3790.86
244_G248_V1.3700.85
629_K634_E1.3670.85
602_M608_N1.3670.85
615_D620_G1.3620.85
514_E518_S1.3580.85
175_A193_T1.3570.85
125_D129_I1.3570.85
598_E629_K1.3570.85
607_A624_V1.3540.85
83_A86_L1.3530.85
444_A456_M1.3490.85
614_A622_A1.3480.84
642_I670_G1.3480.84
589_I638_S1.3480.84
126_A130_T1.3410.84
42_G302_L1.3400.84
126_A276_W1.3400.84
639_A663_I1.3390.84
516_V519_E1.3240.83
724_E728_T1.3200.83
441_V446_M1.3190.83
379_A382_A1.3180.83
727_A734_A1.3170.83
193_T199_I1.3160.83
608_N629_K1.3120.83
530_V608_N1.3080.83
170_G173_E1.3060.83
561_Q598_E1.3060.83
437_L448_D1.3010.82
630_D670_G1.2960.82
526_T636_K1.2930.82
453_F585_E1.2910.82
537_V555_A1.2880.82
537_V562_L1.2880.82
620_G623_V1.2820.81
414_L446_M1.2820.81
629_K723_G1.2810.81
610_E613_R1.2780.81
531_A698_I1.2740.81
579_L709_V1.2740.81
38_I324_L1.2720.81
720_A723_G1.2710.81
583_M663_I1.2670.81
106_D109_H1.2650.80
512_Q640_A1.2610.80
450_A454_N1.2570.80
673_T677_T1.2570.80
677_T691_A1.2530.80
460_M464_I1.2470.79
358_F365_V1.2430.79
243_V246_R1.2410.79
450_A453_F1.2400.79
100_V191_V1.2380.79
522_E708_S1.2340.79
324_L351_L1.2320.79
93_D97_A1.2310.79
339_Y365_V1.2310.79
598_E605_L1.2260.78
179_R270_P1.2240.78
414_L417_T1.2230.78
676_E712_V1.2230.78
592_A663_I1.2200.78
199_I203_F1.2180.78
425_M441_V1.2170.78
374_E377_V1.2170.78
552_Q685_A1.2140.78
327_L331_A1.2040.77
445_A456_M1.1990.77
115_V193_T1.1990.77
373_N377_V1.1950.76
530_V726_T1.1870.76
514_E522_E1.1860.76
496_S738_A1.1850.76
160_V180_V1.1810.76
509_Q709_V1.1790.76
552_Q591_A1.1740.75
510_R598_E1.1730.75
554_A602_M1.1710.75
414_L418_A1.1660.75
635_S645_L1.1660.75
591_A643_E1.1660.75
681_L705_Q1.1650.75
72_V289_G1.1600.74
343_L355_F1.1580.74
609_I640_A1.1570.74
519_E740_Q1.1560.74
215_V279_T1.1540.74
601_N606_N1.1520.74
609_I626_D1.1490.74
513_L517_A1.1490.74
592_A634_E1.1490.74
519_E608_N1.1470.73
682_S706_A1.1450.73
593_I601_N1.1450.73
375_Q378_D1.1370.73
635_S639_A1.1360.73
580_E639_A1.1350.73
610_E629_K1.1310.72
510_R724_E1.1280.72
609_I643_E1.1210.72
519_E551_G1.1200.72
559_V695_V1.1200.72
511_D516_V1.1190.72
598_E617_D1.1180.72
740_Q753_T1.1160.71
679_R682_S1.1160.71
512_Q626_D1.1160.71
421_F453_F1.1150.71
511_D518_S1.1140.71
511_D724_E1.1120.71
509_Q552_Q1.1010.70
359_A363_D1.0970.70
579_L723_G1.0940.70
601_N629_K1.0920.70
494_D739_E1.0920.70
554_A609_I1.0920.70
541_S691_A1.0840.69
512_Q590_V1.0830.69
505_R729_E1.0820.69
629_K645_L1.0750.68
613_R674_V1.0740.68
579_L720_A1.0700.68
372_A379_A1.0640.68
431_G460_M1.0630.68
367_A371_D1.0620.68
548_G602_M1.0570.67
24_L318_R1.0570.67
608_N729_E1.0530.67
303_G307_A1.0520.67
502_I635_S1.0500.67
339_Y369_I1.0500.67
678_E740_Q1.0450.66
627_E670_G1.0430.66
208_P214_L1.0430.66
48_N76_H1.0420.66
207_T215_V1.0410.66
579_L594_T1.0410.66
705_Q712_V1.0410.66
444_A447_A1.0390.66
73_D80_T1.0380.66
548_G596_I1.0380.66
588_T608_N1.0370.66
618_G670_G1.0370.66
495_V506_A1.0340.65
43_G47_L1.0330.65
538_A696_Q1.0320.65
618_G624_V1.0320.65
578_D666_R1.0320.65
152_Q190_V1.0290.65
608_N691_A1.0270.65
521_D708_S1.0260.65
594_T723_G1.0260.65
323_A351_L1.0230.65
621_F625_A1.0200.64
623_V670_G1.0170.64
581_A584_S1.0170.64
306_L314_L1.0160.64
96_N99_E1.0150.64
530_V626_D1.0130.64
450_A533_S1.0110.64
516_V720_A1.0110.64
174_V216_D1.0110.64
233_P236_E1.0100.64
582_K673_T1.0100.64
494_D725_E1.0090.63
31_L313_A1.0030.63
732_S735_D0.9950.62
450_A608_N0.9950.62
614_A625_A0.9950.62
579_L726_T0.9950.62
582_K754_L0.9890.62
740_Q747_V0.9890.62
138_N449_I0.9870.62
335_E544_A0.9860.62
599_Q622_A0.9850.62
417_T447_A0.9840.61
471_A543_R0.9780.61
219_G276_W0.9750.61
207_T213_Q0.9740.61
590_V643_E0.9740.61
508_D719_V0.9740.61
431_G454_N0.9720.61
730_A734_A0.9700.60
534_A667_V0.9670.60
243_V252_P0.9640.60
587_E695_V0.9620.60
76_H85_M0.9610.60
596_I606_N0.9560.59
428_Y457_A0.9520.59
744_L747_V0.9510.59
192_M196_L0.9500.59
97_A134_A0.9480.59
456_M715_A0.9480.59
276_W288_Y0.9450.58
515_A518_S0.9450.58
87_A189_A0.9440.58
639_A645_L0.9430.58
563_E580_E0.9420.58
39_S43_G0.9410.58
554_A673_T0.9390.58
604_A681_L0.9390.58
534_A559_V0.9370.58
593_I620_G0.9360.58
505_R726_T0.9340.57
561_Q726_T0.9330.57
601_N624_V0.9310.57
597_A605_L0.9310.57
663_I681_L0.9300.57
128_V132_T0.9300.57
558_A642_I0.9290.57
622_A670_G0.9290.57
713_T726_T0.9290.57
464_I523_M0.9290.57
468_V751_T0.9280.57
242_I246_R0.9260.57
513_L720_A0.9260.57
672_E712_V0.9250.57
116_R120_Y0.9250.57
29_V305_A0.9150.56
740_Q754_L0.9130.56
524_S643_E0.9130.56
79_R85_M0.9120.56
688_I736_A0.9120.56
330_K341_T0.9120.56
34_V72_V0.9110.56
514_E598_E0.9070.55
347_R362_R0.9040.55
433_L460_M0.9040.55
558_A635_S0.9040.55
87_A92_F0.9010.55
456_M629_K0.9010.55
514_E724_E0.9000.55
555_A740_Q0.8990.55
194_A199_I0.8980.54
501_R505_R0.8970.54
645_L670_G0.8940.54
425_M450_A0.8930.54
494_D731_E0.8930.54
196_L282_V0.8920.54
578_D584_S0.8910.54
609_I636_K0.8910.54
76_H300_L0.8900.54
647_A740_Q0.8900.54
509_Q534_A0.8890.54
320_T343_L0.8880.54
179_R261_D0.8880.54
589_I663_I0.8850.53
608_N628_V0.8850.53
612_A627_E0.8840.53
711_D727_A0.8840.53
602_M629_K0.8840.53
516_V723_G0.8830.53
131_S134_A0.8820.53
422_S452_A0.8820.53
598_E724_E0.8810.53
523_M531_A0.8770.53
345_V359_A0.8770.53
591_A740_Q0.8770.53
549_D558_A0.8760.53
116_R119_H0.8750.53
179_R188_T0.8750.53
530_V609_I0.8750.53
643_E726_T0.8740.52
192_M199_I0.8720.52
50_S54_Q0.8680.52
87_A180_V0.8660.52
264_H276_W0.8660.52
609_I729_E0.8650.52
100_V168_N0.8620.51
76_H84_R0.8620.51
446_M470_F0.8620.51
629_K715_A0.8600.51
617_D716_V0.8590.51
76_H79_R0.8580.51
507_A731_E0.8570.51
433_L531_A0.8560.51
626_D734_A0.8510.50
503_R513_L0.8510.50
168_N171_I0.8500.50
747_V755_A0.8500.50
513_L719_V0.8480.50
418_A475_A0.8470.50
433_L474_V0.8440.50
452_A599_Q0.8420.50
505_R598_E0.8420.50
638_S670_G0.8410.50
502_I754_L0.8400.50
639_A724_E0.8380.49
371_D375_Q0.8370.49
619_D677_T0.8370.49
432_D454_N0.8360.49
208_P212_T0.8360.49
335_E358_F0.8340.49
417_T453_F0.8290.49
126_A133_D0.8290.49
518_S720_A0.8280.49
460_M474_V0.8260.48
26_K365_V0.8260.48
611_A623_V0.8250.48
31_L37_C0.8240.48
276_W283_P0.8240.48
493_R725_E0.8210.48
517_A521_D0.8200.48
680_S722_L0.8190.48
590_V639_A0.8190.48
530_V701_A0.8190.48
593_I646_V0.8170.48
321_V351_L0.8170.48
213_Q279_T0.8160.48
177_V190_V0.8160.48
724_E729_E0.8160.48
23_Y324_L0.8160.48
429_A432_D0.8150.47
595_D602_M0.8150.47
598_E608_N0.8130.47
463_T687_R0.8130.47
594_T640_A0.8110.47
193_T196_L0.8090.47
720_A727_A0.8080.47
548_G678_E0.8070.47
578_D727_A0.8070.47
441_V530_V0.8050.47
332_A353_R0.8050.47
138_N141_F0.8030.46
548_G634_E0.8030.46
591_A641_E0.8010.46
701_A706_A0.8010.46
699_S740_Q0.7980.46
691_A754_L0.7970.46
165_P276_W0.7960.46
507_A711_D0.7960.46
86_L267_A0.7950.46
663_I691_A0.7940.46
211_F225_D0.7940.46
460_M510_R0.7930.46
505_R730_A0.7890.45
620_G641_E0.7890.45
663_I678_E0.7890.45
508_D512_Q0.7890.45
733_T743_T0.7880.45
125_D130_T0.7880.45
723_G726_T0.7870.45
453_F456_M0.7860.45
60_E63_K0.7860.45
518_S522_E0.7850.45
417_T630_D0.7850.45
494_D735_D0.7840.45
646_V691_A0.7840.45
511_D514_E0.7830.45
200_S266_T0.7830.45
424_T437_L0.7830.45
515_A724_E0.7820.45
474_V734_A0.7810.45
511_D726_T0.7810.45
528_E706_A0.7810.45
96_N100_V0.7810.45
735_D738_A0.7800.45
174_V179_R0.7800.45
594_T726_T0.7790.44
498_A502_I0.7770.44
177_V210_S0.7750.44
602_M674_V0.7750.44
514_E726_T0.7750.44
613_R728_T0.7740.44
579_L633_D0.7730.44
304_I311_F0.7730.44
177_V187_R0.7720.44
558_A681_L0.7720.44
189_A287_A0.7710.44
437_L453_F0.7700.44
93_D175_A0.7690.44
554_A720_A0.7670.43
119_H122_S0.7660.43
722_L726_T0.7660.43
505_R609_I0.7660.43
737_A741_A0.7650.43
551_G677_T0.7640.43
598_E628_V0.7610.43
361_L530_V0.7610.43
551_G750_Q0.7610.43
462_A500_G0.7600.43
610_E615_D0.7570.43
44_V316_L0.7560.43
596_I624_V0.7550.42
121_V128_V0.7540.42
640_A719_V0.7530.42
624_V627_E0.7530.42
608_N667_V0.7520.42
362_R366_Q0.7520.42
448_D452_A0.7520.42
595_D633_D0.7510.42
33_A316_L0.7500.42
368_R372_A0.7500.42
436_R457_A0.7500.42
514_E594_T0.7480.42
598_E720_A0.7470.42
547_L683_E0.7470.42
137_R140_S0.7460.42
117_D145_A0.7460.42
638_S642_I0.7460.42
242_I270_P0.7450.42
243_V248_V0.7440.42
148_W166_Y0.7440.42
593_I618_G0.7440.42
210_S225_D0.7420.41
500_G710_S0.7420.41
629_K754_L0.7390.41
264_H283_P0.7390.41
222_I226_S0.7360.41
331_A334_L0.7360.41
535_D703_D0.7350.41
593_I638_S0.7350.41
580_E684_I0.7340.41
251_Q553_A0.7340.41
303_G336_R0.7340.41
72_V214_L0.7320.41
149_S193_T0.7310.40
307_A716_V0.7290.40
494_D527_I0.7290.40
709_V726_T0.7280.40
517_A719_V0.7250.40
79_R82_N0.7250.40
498_A608_N0.7250.40
538_A691_A0.7250.40
531_A642_I0.7240.40
464_I467_V0.7230.40
516_V522_E0.7230.40
630_D730_A0.7220.40
645_L678_E0.7210.40
80_T83_A0.7200.40
605_L704_D0.7190.40
719_V730_A0.7170.39
450_A709_V0.7170.39
579_L729_E0.7160.39
196_L283_P0.7150.39
431_G613_R0.7140.39
519_E711_D0.7130.39
598_E602_M0.7120.39
360_S365_V0.7110.39
247_A251_Q0.7110.39
104_F128_V0.7080.39
163_S166_Y0.7070.39
127_R130_T0.7070.39
216_D220_S0.7070.39
711_D714_T0.7060.38
533_S630_D0.7050.38
605_L623_V0.7050.38
494_D676_E0.7040.38
467_V474_V0.7030.38
425_M437_L0.7030.38
638_S705_Q0.7020.38
52_H317_G0.7020.38
608_N613_R0.7010.38
604_A667_V0.7000.38
449_I521_D0.6980.38
626_D719_V0.6960.38
439_A671_V0.6950.38
512_Q719_V0.6950.38
216_D219_G0.6950.38
562_L670_G0.6950.38
592_A670_G0.6940.38
166_Y175_A0.6940.38
588_T744_L0.6930.37
705_Q724_E0.6920.37
467_V585_E0.6910.37
598_E723_G0.6910.37
284_T288_Y0.6900.37
120_Y191_V0.6890.37
432_D456_M0.6890.37
579_L643_E0.6880.37
337_G361_L0.6880.37
634_E720_A0.6880.37
205_D215_V0.6870.37
588_T730_A0.6870.37
526_T530_V0.6870.37
618_G642_I0.6860.37
148_W276_W0.6850.37
595_D634_E0.6850.37
548_G685_A0.6850.37
495_V663_I0.6840.37
113_S117_D0.6830.37
550_D553_A0.6820.37
30_A318_R0.6800.36
602_M642_I0.6800.36
72_V198_A0.6800.36
97_A117_D0.6790.36
456_M740_Q0.6770.36
530_V709_V0.6750.36
56_S311_F0.6750.36
417_T450_A0.6740.36
138_N143_S0.6740.36
530_V674_V0.6740.36
523_M619_D0.6730.36
460_M754_L0.6710.36
149_S274_T0.6710.36
510_R594_T0.6700.36
418_A453_F0.6680.35
639_A727_A0.6680.35
101_Q222_I0.6670.35
523_M716_V0.6670.35
586_I626_D0.6660.35
598_E670_G0.6640.35
79_R90_G0.6640.35
686_G693_T0.6640.35
22_S25_A0.6620.35
460_M582_K0.6620.35
638_S678_E0.6610.35
434_T454_N0.6600.35
454_N674_V0.6600.35
496_S639_A0.6590.35
215_V276_W0.6590.35
598_E634_E0.6590.35
509_Q613_R0.6590.35
626_D633_D0.6590.35
716_V719_V0.6580.35
364_T369_I0.6560.35
130_T134_A0.6550.35
453_F608_N0.6550.35
734_A739_E0.6550.35
417_T421_F0.6540.34
670_G673_T0.6540.34
411_A417_T0.6540.34
544_A622_A0.6540.34
546_A679_R0.6540.34
636_K730_A0.6540.34
744_L754_L0.6530.34
563_E675_S0.6530.34
211_F221_V0.6520.34
129_I172_T0.6520.34
616_Q623_V0.6510.34
551_G737_A0.6460.34
614_A623_V0.6450.34
151_Q154_T0.6450.34
216_D222_I0.6450.34
512_Q583_M0.6430.34
464_I751_T0.6420.34
697_E700_N0.6420.34
152_Q177_V0.6410.33
665_E669_D0.6410.33
699_S747_V0.6400.33
543_R546_A0.6390.33
663_I670_G0.6380.33
53_L57_S0.6370.33
666_R681_L0.6360.33
527_I688_I0.6360.33
456_M464_I0.6350.33
308_G749_A0.6350.33
62_K76_H0.6340.33
544_A681_L0.6340.33
526_T559_V0.6340.33
167_V170_G0.6340.33
439_A451_A0.6340.33
506_A726_T0.6330.33
593_I712_V0.6320.33
421_F427_A0.6320.33
327_L355_F0.6320.33
433_L457_A0.6300.33
65_A126_A0.6300.33
561_Q594_T0.6300.33
530_V691_A0.6290.33
210_S224_D0.6270.32
207_T744_L0.6270.32
593_I610_E0.6260.32
594_T636_K0.6260.32
594_T729_E0.6250.32
165_P175_A0.6240.32
612_A618_G0.6240.32
665_E702_M0.6230.32
79_R87_A0.6220.32
506_A590_V0.6200.32
27_F42_G0.6200.32
593_I623_V0.6200.32
187_R243_V0.6200.32
718_D723_G0.6190.32
498_A579_L0.6180.32
177_V290_L0.6180.32
602_M630_D0.6170.32
101_Q105_T0.6170.32
464_I499_V0.6150.32
175_A178_A0.6120.31
608_N617_D0.6120.31
90_G125_D0.6120.31
179_R276_W0.6120.31
21_R32_L0.6110.31
620_G624_V0.6110.31
664_Q668_S0.6100.31
62_K81_N0.6090.31
136_L139_A0.6090.31
411_A415_E0.6090.31
495_V673_T0.6070.31
24_L312_I0.6070.31
459_D753_T0.6070.31
512_Q712_V0.6070.31
505_R723_G0.6060.31
516_V548_G0.6060.31
595_D598_E0.6060.31
371_D383_R0.6060.31
701_A705_Q0.6060.31
548_G555_A0.6050.31
505_R720_A0.6050.31
265_E268_Y0.6040.31
368_R371_D0.6040.31
599_Q608_N0.6030.31
93_D117_D0.6030.31
301_I331_A0.6030.31
715_A723_G0.6010.31
612_A670_G0.6010.31
494_D720_A0.6000.30
506_A663_I0.6000.30
521_D525_A0.6000.30
537_V743_T0.5990.30
519_E712_V0.5980.30
63_K462_A0.5970.30
596_I634_E0.5960.30
213_Q278_V0.5960.30
561_Q608_N0.5960.30
289_G328_E0.5940.30
35_V254_A0.5940.30
530_V579_L0.5940.30
617_D711_D0.5930.30
715_A740_Q0.5920.30
598_E639_A0.5920.30
66_E69_S0.5910.30
362_R558_A0.5900.30
500_G716_V0.5900.30
608_N711_D0.5890.30
45_M323_A0.5880.30
512_Q595_D0.5870.30
551_G694_G0.5870.30
609_I709_V0.5870.30
588_T691_A0.5860.29
301_I333_A0.5860.29
535_D538_A0.5860.29
587_E593_I0.5850.29
171_I234_Y0.5850.29
446_M601_N0.5850.29
425_M639_A0.5850.29
126_A134_A0.5840.29
635_S642_I0.5830.29
83_A192_M0.5830.29
519_E529_E0.5830.29
185_G194_A0.5830.29
583_M642_I0.5830.29
558_A602_M0.5820.29
30_A33_A0.5820.29
523_M526_T0.5820.29
512_Q726_T0.5810.29
115_V121_V0.5810.29
354_L360_S0.5810.29
417_T441_V0.5800.29
189_A712_V0.5800.29
503_R510_R0.5800.29
593_I636_K0.5790.29
525_A543_R0.5790.29
611_A625_A0.5790.29
510_R720_A0.5790.29
514_E731_E0.5790.29
507_A728_T0.5780.29
84_R89_Y0.5760.29
688_I691_A0.5750.29
414_L506_A0.5750.29
146_A168_N0.5730.29
594_T645_L0.5730.29
513_L639_A0.5730.29
586_I620_G0.5730.29
39_S432_D0.5720.28
677_T705_Q0.5720.28
681_L740_Q0.5720.28
586_I610_E0.5720.28
507_A723_G0.5720.28
527_I705_Q0.5720.28
165_P193_T0.5700.28
588_T743_T0.5690.28
302_L357_A0.5680.28
148_W152_Q0.5680.28
54_Q265_E0.5670.28
520_T716_V0.5660.28
528_E710_S0.5650.28
115_V133_D0.5650.28
510_R709_V0.5650.28
174_V222_I0.5650.28
523_M677_T0.5650.28
551_G594_T0.5650.28
734_A738_A0.5650.28
27_F317_G0.5640.28
454_N594_T0.5640.28
330_K343_L0.5640.28
355_F362_R0.5640.28
595_D719_V0.5640.28
496_S741_A0.5590.28
425_M589_I0.5590.28
28_G68_S0.5580.28
582_K671_V0.5570.27
615_D627_E0.5570.27
606_N620_G0.5570.27
300_L304_I0.5570.27
23_Y323_A0.5560.27
629_K636_K0.5560.27
179_R349_D0.5540.27
350_E632_A0.5540.27
75_W199_I0.5540.27
561_Q634_E0.5530.27
321_V550_D0.5520.27
609_I733_T0.5520.27
617_D695_V0.5520.27
594_T639_A0.5510.27
104_F120_Y0.5500.27
615_D623_V0.5500.27
496_S526_T0.5490.27
150_R154_T0.5490.27
527_I718_D0.5460.27
179_R189_A0.5450.27
502_I673_T0.5450.27
507_A555_A0.5450.27
165_P174_V0.5450.27
512_Q561_Q0.5430.27
441_V579_L0.5430.27
319_G474_V0.5430.27
425_M428_Y0.5420.26
456_M460_M0.5410.26
663_I667_V0.5400.26
719_V727_A0.5390.26
594_T638_S0.5380.26
598_E754_L0.5370.26
41_A45_M0.5370.26
444_A453_F0.5370.26
513_L555_A0.5360.26
516_V640_A0.5360.26
129_I270_P0.5350.26
610_E628_V0.5350.26
667_V677_T0.5350.26
41_A302_L0.5340.26
200_S212_T0.5330.26
369_I372_A0.5330.26
439_A446_M0.5330.26
635_S670_G0.5330.26
462_A640_A0.5300.26
548_G737_A0.5300.26
517_A622_A0.5300.26
179_R219_G0.5300.26
582_K634_E0.5300.26
191_V199_I0.5300.26
667_V678_E0.5290.26
34_V324_L0.5290.26
509_Q643_E0.5290.26
541_S551_G0.5290.26
210_S219_G0.5290.26
592_A639_A0.5270.25
613_R720_A0.5270.25
125_D132_T0.5260.25
555_A667_V0.5260.25
648_E669_D0.5250.25
267_A270_P0.5250.25
331_A335_E0.5250.25
614_A620_G0.5250.25
210_S282_V0.5250.25
421_F424_T0.5240.25
334_L437_L0.5240.25
207_T259_E0.5230.25
72_V148_W0.5220.25
720_A729_E0.5220.25
87_A191_V0.5220.25
598_E729_E0.5220.25
121_V129_I0.5220.25
342_D366_Q0.5220.25
598_E645_L0.5220.25
441_V453_F0.5210.25
347_R359_A0.5210.25
613_R626_D0.5210.25
95_D100_V0.5200.25
635_S726_T0.5200.25
519_E694_G0.5200.25
549_D680_S0.5190.25
608_N743_T0.5180.25
551_G681_L0.5180.25
206_P210_S0.5180.25
60_E69_S0.5170.25
585_E589_I0.5160.25
747_V756_E0.5160.25
429_A635_S0.5160.25
446_M456_M0.5150.25
510_R515_A0.5150.25
498_A719_V0.5150.25
615_D622_A0.5150.25
639_A723_G0.5140.25
454_N458_A0.5130.25
562_L712_V0.5120.25
600_T605_L0.5110.24
534_A671_V0.5110.24
533_S729_E0.5090.24
418_A447_A0.5090.24
219_G282_V0.5090.24
511_D519_E0.5080.24
715_A726_T0.5080.24
645_L663_I0.5070.24
561_Q599_Q0.5070.24
520_T738_A0.5070.24
473_E533_S0.5050.24
358_F579_L0.5050.24
537_V613_R0.5040.24
537_V733_T0.5040.24
618_G629_K0.5040.24
605_L615_D0.5030.24
495_V499_V0.5030.24
375_Q382_A0.5030.24
609_I633_D0.5020.24
499_V680_S0.5010.24
203_F289_G0.5010.24
624_V628_V0.5010.24
667_V674_V0.5000.24
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zx6A 2 0.3907 100 0.616 Contact Map
1qu7A 2 0.2918 100 0.673 Contact Map
2ch7A 2 0.3972 100 0.685 Contact Map
3g67A 2 0.2686 100 0.746 Contact Map
4i3mA 2 0.1928 99.9 0.853 Contact Map
3lifA 1 0.3046 99.8 0.873 Contact Map
3e4oA 2 0.2853 99.8 0.876 Contact Map
3c8cA 2 0.3008 99.8 0.878 Contact Map
3licA 2 0.2969 99.8 0.878 Contact Map
3li9A 2 0.2943 99.8 0.879 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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