RPOB2 - HALSA - GREMLIN Contacts

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RPOB2 - DNA-directed RNA polymerase subunit B''

UniProt:	P0CX04	Sequences: MLQEDKRELSESYFSKERLAEHHFRSYNAFLEHGMQDVVTEKERIETDIGDKEDEEPVWVELGDVRAVTPRVREADGSEELLYPQEARLRNITYSAPVFMEMSIVRGGEEEEERVLDTTETKVGRMPIMVGSDKCNISGFSDEELIEIGEDPADPGGYFIINGSERVLMTSEDLAPNKILAEYDSKYGDEIQVAKTFSQRRGYRALVLVERNREGLLEVSFPSVSGSISFVTLVRALGLESDEEIVHRVSEDPEIVKFMLENLEEADVQTQEEAIEDLGQRVASGQGKNYQLKRANYVIDRYLLPHLHEDGVEEEETRINKAYYLCRMAEACFELALGRREADDKDHYANKRLKVSGDLMKDLFRTALNKLARDVKYQLERANMRNRELTVNTVVRSDVLTERLEHPIATGNWVGGRSGVSQLVDRTDFMGVLSHLRRLRSPLSRSQPHFEARDLHATQWGRICPSETPEGPNCGLVKNFAQAMELSQDVDDERDLKQELSSMGVEGIPGISMETTSTTSADD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	523 (448)
Sequences:	2421 (1197)
Seq/√Len:	56.5

ECOLI - RPOB
BACSU - RPOB
HALSA - RPOB2
SULSO - Q980R0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
230_F	329_A	6.515	1.00
21_E	25_R	6.394	1.00
315_E	331_A	5.915	1.00
36_Q	62_L	5.511	1.00
36_Q	64_D	4.917	1.00
68_V	97_P	4.863	1.00
270_T	273_E	4.539	1.00
36_Q	40_T	4.416	1.00
64_D	101_E	3.368	1.00
217_L	333_F	3.340	1.00
61_E	103_S	3.176	1.00
46_E	59_W	3.141	1.00
439_L	463_I	3.046	1.00
86_E	90_R	2.973	1.00
62_L	372_A	2.943	1.00
268_V	274_A	2.914	1.00
239_L	248_R	2.889	1.00
166_R	421_S	2.864	1.00
306_H	488_Q	2.822	1.00
243_E	247_H	2.814	1.00
28_N	32_E	2.771	1.00
141_S	144_E	2.751	1.00
26_S	357_G	2.685	1.00
434_S	479_N	2.618	1.00
194_A	198_S	2.503	1.00
29_A	33_H	2.421	1.00
334_E	340_R	2.368	1.00
59_W	105_V	2.345	1.00
498_Q	509_P	2.273	1.00
198_S	201_R	2.265	1.00
277_D	280_Q	2.243	1.00
196_T	201_R	2.187	1.00
109_E	139_G	2.132	1.00
480_F	492_D	2.128	1.00
235_R	242_D	2.124	1.00
66_R	99_F	2.093	1.00
334_E	339_R	2.066	1.00
262_N	266_A	2.050	1.00
271_Q	275_I	2.041	1.00
248_R	326_C	2.009	1.00
422_Q	456_H	2.001	1.00
96_A	153_A	1.997	1.00
106_R	109_E	1.983	1.00
140_F	144_E	1.970	1.00
63_G	103_S	1.969	1.00
271_Q	294_R	1.968	1.00
432_V	436_L	1.942	1.00
487_S	493_E	1.926	1.00
37_D	40_T	1.919	1.00
194_A	201_R	1.918	1.00
263_L	266_A	1.900	1.00
290_Y	293_K	1.896	1.00
29_A	34_G	1.843	0.99
24_F	28_N	1.828	0.99
43_E	102_M	1.810	0.99
434_S	467_E	1.787	0.99
234_V	326_C	1.780	0.99
289_N	292_L	1.769	0.99
335_L	342_A	1.744	0.99
68_V	96_A	1.736	0.99
500_L	503_M	1.718	0.99
209_V	328_M	1.708	0.99
467_E	479_N	1.686	0.99
196_T	209_V	1.667	0.99
291_Q	295_A	1.656	0.99
351_K	413_W	1.644	0.99
233_L	325_L	1.644	0.99
217_L	230_F	1.632	0.99
290_Y	294_R	1.626	0.99
38_V	41_E	1.618	0.99
259_M	262_N	1.615	0.99
395_V	399_V	1.605	0.99
441_S	459_Q	1.601	0.98
234_V	239_L	1.590	0.98
196_T	200_R	1.590	0.98
240_E	271_Q	1.586	0.98
68_V	99_F	1.582	0.98
206_L	209_V	1.565	0.98
257_K	261_E	1.561	0.98
35_M	65_V	1.556	0.98
394_V	463_I	1.555	0.98
500_L	505_V	1.547	0.98
239_L	322_A	1.508	0.98
467_E	470_E	1.505	0.98
172_E	407_P	1.497	0.98
103_S	143_E	1.490	0.98
73_R	87_A	1.489	0.98
288_K	292_L	1.469	0.97
38_V	42_K	1.465	0.97
239_L	245_I	1.458	0.97
333_F	337_L	1.457	0.97
192_Q	198_S	1.453	0.97
234_V	329_A	1.447	0.97
35_M	364_F	1.427	0.97
359_L	433_L	1.413	0.97
499_E	504_G	1.413	0.97
189_D	194_A	1.392	0.96
26_S	165_E	1.377	0.96
228_I	381_R	1.371	0.96
230_F	325_L	1.371	0.96
160_I	320_N	1.367	0.96
258_F	261_E	1.359	0.96
438_R	467_E	1.352	0.96
21_E	485_E	1.349	0.96
207_V	211_R	1.345	0.96
331_A	340_R	1.341	0.95
32_E	161_I	1.339	0.95
423_L	432_V	1.335	0.95
436_L	467_E	1.333	0.95
170_T	353_L	1.332	0.95
416_G	479_N	1.325	0.95
406_H	413_W	1.324	0.95
166_R	416_G	1.309	0.95
63_G	101_E	1.304	0.95
261_E	264_E	1.302	0.95
412_N	423_L	1.301	0.95
70_P	73_R	1.286	0.94
424_V	436_L	1.286	0.94
35_M	64_D	1.278	0.94
453_R	475_G	1.277	0.94
172_E	478_K	1.276	0.94
37_D	361_K	1.274	0.94
422_Q	438_R	1.272	0.94
453_R	464_C	1.267	0.94
257_K	263_L	1.264	0.94
194_A	199_Q	1.253	0.93
232_T	268_V	1.252	0.93
245_I	329_A	1.252	0.93
344_D	456_H	1.242	0.93
178_K	328_M	1.242	0.93
259_M	329_A	1.240	0.93
207_V	325_L	1.239	0.93
34_G	361_K	1.233	0.93
288_K	291_Q	1.229	0.93
267_D	364_F	1.228	0.93
422_Q	435_H	1.222	0.93
471_G	475_G	1.221	0.93
391_V	395_V	1.220	0.93
462_R	473_N	1.218	0.92
182_E	190_E	1.217	0.92
152_P	421_S	1.212	0.92
246_V	260_L	1.206	0.92
140_F	148_I	1.205	0.92
6_K	13_Y	1.204	0.92
333_F	336_A	1.204	0.92
235_R	267_D	1.203	0.92
276_E	280_Q	1.201	0.92
317_T	321_K	1.199	0.92
345_K	351_K	1.192	0.92
215_G	329_A	1.189	0.92
464_C	468_T	1.174	0.91
326_C	330_E	1.160	0.90
219_V	230_F	1.160	0.90
240_E	244_E	1.149	0.90
58_V	104_I	1.146	0.90
290_Y	295_A	1.145	0.90
351_K	449_H	1.142	0.90
300_D	318_R	1.142	0.90
335_L	340_R	1.142	0.90
404_L	408_I	1.137	0.90
259_M	333_F	1.133	0.89
158_Y	410_T	1.133	0.89
195_K	443_L	1.133	0.89
242_D	268_V	1.130	0.89
500_L	504_G	1.129	0.89
291_Q	294_R	1.127	0.89
455_L	474_C	1.126	0.89
312_V	317_T	1.125	0.89
184_D	187_Y	1.124	0.89
156_G	181_A	1.123	0.89
30_F	407_P	1.117	0.89
255_I	258_F	1.116	0.89
194_A	200_R	1.116	0.89
225_S	282_V	1.115	0.89
461_G	494_R	1.114	0.89
165_E	235_R	1.111	0.88
196_T	328_M	1.107	0.88
445_R	473_N	1.103	0.88
443_L	452_A	1.095	0.88
27_Y	298_V	1.093	0.88
106_R	144_E	1.092	0.88
209_V	332_C	1.091	0.88
88_R	156_G	1.088	0.87
245_I	249_V	1.086	0.87
244_E	247_H	1.085	0.87
25_R	29_A	1.081	0.87
252_D	255_I	1.078	0.87
506_E	509_P	1.069	0.86
65_V	98_V	1.065	0.86
140_F	143_E	1.065	0.86
166_R	206_L	1.061	0.86
259_M	263_L	1.061	0.86
18_R	24_F	1.053	0.86
505_V	509_P	1.046	0.85
46_E	50_G	1.043	0.85
450_F	454_D	1.039	0.85
248_R	330_E	1.037	0.85
156_G	408_I	1.031	0.84
406_H	410_T	1.030	0.84
464_C	471_G	1.027	0.84
460_W	474_C	1.026	0.84
498_Q	507_G	1.025	0.84
438_R	470_E	1.024	0.84
351_K	438_R	1.021	0.84
208_L	474_C	1.021	0.84
258_F	262_N	1.021	0.84
20_A	301_R	1.018	0.84
31_L	40_T	1.018	0.84
453_R	471_G	1.012	0.83
501_S	504_G	1.009	0.83
67_A	98_V	1.009	0.83
416_G	467_E	1.008	0.83
228_I	233_L	1.007	0.83
252_D	258_F	1.006	0.83
145_L	150_E	0.999	0.83
435_H	473_N	0.994	0.82
25_R	28_N	0.992	0.82
377_Y	381_R	0.992	0.82
353_L	486_L	0.991	0.82
425_D	432_V	0.988	0.82
500_L	507_G	0.981	0.81
45_I	48_D	0.977	0.81
391_V	394_V	0.977	0.81
445_R	467_E	0.976	0.81
505_V	508_I	0.972	0.81
93_T	161_I	0.972	0.81
290_Y	463_I	0.970	0.81
470_E	477_V	0.963	0.80
196_T	207_V	0.958	0.80
375_V	394_V	0.958	0.80
428_D	466_S	0.958	0.80
406_H	409_A	0.958	0.80
454_D	462_R	0.956	0.80
500_L	508_I	0.953	0.79
30_F	360_M	0.950	0.79
392_N	396_R	0.950	0.79
503_M	506_E	0.950	0.79
289_N	295_A	0.948	0.79
22_H	480_F	0.945	0.79
249_V	259_M	0.944	0.79
465_P	468_T	0.943	0.79
41_E	361_K	0.942	0.79
370_K	374_D	0.936	0.78
29_A	361_K	0.935	0.78
98_V	266_A	0.935	0.78
169_M	443_L	0.934	0.78
210_E	220_S	0.932	0.78
197_F	201_R	0.932	0.78
499_E	502_S	0.929	0.78
296_N	303_L	0.925	0.77
165_E	357_G	0.922	0.77
91_N	363_L	0.916	0.77
481_A	494_R	0.915	0.77
14_F	412_N	0.910	0.76
274_A	438_R	0.910	0.76
103_S	145_L	0.908	0.76
312_V	316_E	0.905	0.76
194_A	332_C	0.903	0.76
207_V	212_N	0.903	0.76
465_P	469_P	0.902	0.76
41_E	365_R	0.902	0.76
422_Q	467_E	0.901	0.75
18_R	21_E	0.901	0.75
485_E	493_E	0.900	0.75
456_H	470_E	0.897	0.75
182_E	185_S	0.895	0.75
98_V	364_F	0.894	0.75
156_G	508_I	0.893	0.75
297_Y	301_R	0.891	0.75
167_V	422_Q	0.890	0.75
38_V	361_K	0.890	0.75
283_A	286_Q	0.883	0.74
20_A	433_L	0.880	0.74
32_E	37_D	0.879	0.74
456_H	459_Q	0.879	0.74
248_R	323_Y	0.878	0.74
232_T	328_M	0.875	0.73
42_K	45_I	0.875	0.73
497_K	505_V	0.875	0.73
228_I	278_L	0.873	0.73
167_V	438_R	0.872	0.73
161_I	170_T	0.871	0.73
66_R	145_L	0.870	0.73
379_L	486_L	0.869	0.73
276_E	290_Y	0.867	0.73
168_L	191_I	0.858	0.72
88_R	160_I	0.858	0.72
32_E	393_T	0.857	0.72
373_R	409_A	0.852	0.71
438_R	459_Q	0.851	0.71
33_H	37_D	0.849	0.71
168_L	293_K	0.848	0.71
453_R	468_T	0.845	0.71
29_A	37_D	0.844	0.71
330_E	339_R	0.843	0.70
156_G	314_E	0.839	0.70
461_G	475_G	0.839	0.70
407_P	458_T	0.838	0.70
247_H	251_E	0.838	0.70
398_D	433_L	0.833	0.70
269_Q	273_E	0.832	0.69
255_I	337_L	0.830	0.69
40_T	46_E	0.828	0.69
503_M	507_G	0.826	0.69
88_R	165_E	0.823	0.69
498_Q	501_S	0.821	0.68
289_N	294_R	0.821	0.68
20_A	418_S	0.816	0.68
139_G	282_V	0.816	0.68
372_A	376_K	0.814	0.68
325_L	329_A	0.813	0.68
422_Q	470_E	0.811	0.68
45_I	162_N	0.808	0.67
187_Y	190_E	0.808	0.67
209_V	213_R	0.807	0.67
500_L	506_E	0.807	0.67
95_S	150_E	0.807	0.67
42_K	49_I	0.807	0.67
238_G	245_I	0.804	0.67
448_P	452_A	0.802	0.67
195_K	225_S	0.801	0.67
156_G	242_D	0.800	0.66
168_L	421_S	0.799	0.66
272_E	294_R	0.798	0.66
221_F	278_L	0.797	0.66
374_D	378_Q	0.795	0.66
99_F	486_L	0.795	0.66
368_L	433_L	0.794	0.66
44_R	373_R	0.794	0.66
423_L	426_R	0.793	0.66
186_K	305_P	0.791	0.66
441_S	467_E	0.788	0.65
219_V	295_A	0.788	0.65
395_V	398_D	0.787	0.65
33_H	36_Q	0.787	0.65
167_V	353_L	0.784	0.65
443_L	450_F	0.784	0.65
218_E	458_T	0.783	0.65
160_I	253_P	0.782	0.65
480_F	486_L	0.782	0.65
144_E	147_E	0.781	0.65
57_P	364_F	0.778	0.64
11_E	67_A	0.776	0.64
442_P	456_H	0.773	0.64
458_T	467_E	0.773	0.64
67_A	96_A	0.772	0.64
98_V	223_S	0.770	0.63
312_V	321_K	0.769	0.63
272_E	290_Y	0.769	0.63
106_R	390_T	0.767	0.63
468_T	475_G	0.765	0.63
174_L	309_E	0.764	0.63
235_R	268_V	0.764	0.63
61_E	105_V	0.763	0.63
108_G	272_E	0.763	0.63
151_D	156_G	0.762	0.63
427_T	463_I	0.761	0.63
452_A	477_V	0.759	0.62
100_M	368_L	0.759	0.62
193_V	245_I	0.758	0.62
299_I	306_H	0.755	0.62
434_S	451_E	0.754	0.62
413_W	417_R	0.754	0.62
105_V	108_G	0.751	0.62
163_G	471_G	0.750	0.61
33_H	40_T	0.747	0.61
195_K	199_Q	0.747	0.61
87_A	90_R	0.747	0.61
59_W	107_G	0.746	0.61
304_L	359_L	0.746	0.61
10_S	20_A	0.746	0.61
143_E	147_E	0.743	0.61
426_R	432_V	0.742	0.61
208_L	459_Q	0.741	0.60
378_Q	396_R	0.740	0.60
99_F	143_E	0.737	0.60
416_G	435_H	0.737	0.60
234_V	325_L	0.737	0.60
43_E	47_T	0.737	0.60
89_L	214_E	0.735	0.60
191_I	211_R	0.734	0.60
353_L	463_I	0.730	0.59
70_P	74_E	0.729	0.59
231_V	263_L	0.728	0.59
257_K	260_L	0.728	0.59
25_R	507_G	0.727	0.59
6_K	11_E	0.725	0.59
358_D	414_V	0.724	0.59
106_R	139_G	0.723	0.59
443_L	451_E	0.721	0.58
451_E	454_D	0.718	0.58
165_E	469_P	0.718	0.58
350_N	415_G	0.716	0.58
186_K	247_H	0.715	0.58
87_A	93_T	0.712	0.57
288_K	293_K	0.711	0.57
63_G	395_V	0.711	0.57
259_M	266_A	0.710	0.57
190_E	194_A	0.707	0.57
375_V	397_S	0.707	0.57
11_E	14_F	0.707	0.57
18_R	22_H	0.705	0.57
58_V	107_G	0.702	0.56
193_V	201_R	0.701	0.56
218_E	227_S	0.700	0.56
187_Y	196_T	0.699	0.56
444_S	473_N	0.699	0.56
462_R	466_S	0.698	0.56
26_S	355_V	0.697	0.56
201_R	207_V	0.695	0.56
10_S	13_Y	0.694	0.55
43_E	61_E	0.691	0.55
425_D	428_D	0.691	0.55
309_E	490_V	0.690	0.55
7_R	332_C	0.687	0.55
443_L	448_P	0.684	0.54
450_F	473_N	0.684	0.54
363_L	407_P	0.681	0.54
102_M	233_L	0.680	0.54
57_P	66_R	0.680	0.54
254_E	257_K	0.680	0.54
424_V	431_G	0.679	0.54
374_D	377_Y	0.677	0.54
156_G	312_V	0.673	0.53
342_A	375_V	0.672	0.53
8_E	12_S	0.672	0.53
90_R	357_G	0.671	0.53
26_S	435_H	0.671	0.53
428_D	437_R	0.671	0.53
91_N	98_V	0.670	0.53
374_D	394_V	0.669	0.53
501_S	507_G	0.666	0.52
371_L	379_L	0.666	0.52
39_V	97_P	0.665	0.52
424_V	452_A	0.665	0.52
212_N	218_E	0.664	0.52
19_L	433_L	0.663	0.52
248_R	353_L	0.663	0.52
370_K	399_V	0.661	0.52
207_V	210_E	0.660	0.52
259_M	330_E	0.659	0.52
423_L	436_L	0.659	0.52
331_A	335_L	0.658	0.52
283_A	291_Q	0.656	0.51
219_V	233_L	0.655	0.51
464_C	475_G	0.654	0.51
262_N	275_I	0.654	0.51
449_H	479_N	0.651	0.51
62_L	368_L	0.650	0.51
470_E	479_N	0.650	0.51
256_V	260_L	0.649	0.51
314_E	317_T	0.648	0.51
426_R	446_S	0.648	0.51
6_K	9_L	0.646	0.50
424_V	482_Q	0.644	0.50
282_V	285_G	0.643	0.50
169_M	437_R	0.643	0.50
267_D	273_E	0.643	0.50
208_L	211_R	0.642	0.50
230_F	353_L	0.642	0.50
212_N	289_N	0.641	0.50
29_A	358_D	0.640	0.50
168_L	356_S	0.639	0.50
308_H	343_D	0.639	0.50
435_H	479_N	0.636	0.49
459_Q	467_E	0.636	0.49
162_N	405_E	0.635	0.49
455_L	465_P	0.631	0.49
166_R	192_Q	0.631	0.49
184_D	190_E	0.630	0.49
503_M	509_P	0.628	0.48
43_E	377_Y	0.627	0.48
288_K	295_A	0.626	0.48
375_V	391_V	0.625	0.48
345_K	447_Q	0.625	0.48
67_A	502_S	0.625	0.48
447_Q	454_D	0.624	0.48
10_S	457_A	0.624	0.48
188_G	353_L	0.624	0.48
343_D	350_N	0.623	0.48
350_N	430_M	0.622	0.48
27_Y	62_L	0.621	0.48
252_D	337_L	0.620	0.47
501_S	505_V	0.618	0.47
185_S	338_G	0.618	0.47
416_G	441_S	0.616	0.47
227_S	370_K	0.616	0.47
247_H	498_Q	0.616	0.47
348_Y	432_V	0.616	0.47
152_P	422_Q	0.616	0.47
425_D	431_G	0.615	0.47
502_S	507_G	0.614	0.47
284_S	287_G	0.614	0.47
189_D	192_Q	0.613	0.47
453_R	470_E	0.609	0.46
250_S	439_L	0.608	0.46
408_I	411_G	0.608	0.46
88_R	281_R	0.606	0.46
179_I	194_A	0.605	0.46
46_E	105_V	0.604	0.46
156_G	419_G	0.603	0.46
13_Y	497_K	0.600	0.45
451_E	467_E	0.600	0.45
422_Q	432_V	0.599	0.45
260_L	509_P	0.598	0.45
406_H	412_N	0.595	0.45
201_R	206_L	0.594	0.45
16_K	482_Q	0.593	0.45
196_T	199_Q	0.593	0.45
262_N	350_N	0.593	0.45
364_F	411_G	0.592	0.44
109_E	140_F	0.592	0.44
242_D	270_T	0.591	0.44
48_D	376_K	0.591	0.44
246_V	278_L	0.591	0.44
97_P	149_G	0.591	0.44
464_C	469_P	0.589	0.44
275_I	296_N	0.589	0.44
461_G	468_T	0.588	0.44
255_I	260_L	0.588	0.44
152_P	470_E	0.588	0.44
39_V	377_Y	0.587	0.44
41_E	46_E	0.587	0.44
25_R	488_Q	0.587	0.44
466_S	473_N	0.586	0.44
290_Y	376_K	0.585	0.44
28_N	38_V	0.585	0.44
232_T	274_A	0.583	0.43
9_L	158_Y	0.583	0.43
304_L	439_L	0.583	0.43
7_R	424_V	0.583	0.43
237_L	312_V	0.583	0.43
235_R	312_V	0.582	0.43
420_V	426_R	0.581	0.43
332_C	336_A	0.580	0.43
151_D	154_D	0.580	0.43
507_G	510_G	0.580	0.43
348_Y	459_Q	0.580	0.43
158_Y	165_E	0.579	0.43
371_L	405_E	0.579	0.43
139_G	336_A	0.578	0.43
447_Q	472_P	0.577	0.43
233_L	248_R	0.577	0.43
508_I	511_I	0.574	0.42
437_R	456_H	0.573	0.42
448_P	454_D	0.572	0.42
287_G	292_L	0.571	0.42
23_H	169_M	0.571	0.42
210_E	481_A	0.570	0.42
188_G	191_I	0.569	0.42
172_E	451_E	0.568	0.42
268_V	273_E	0.568	0.42
206_L	418_S	0.567	0.42
151_D	411_G	0.567	0.42
68_V	269_Q	0.566	0.42
285_G	301_R	0.564	0.41
171_S	440_R	0.564	0.41
499_E	503_M	0.563	0.41
351_K	367_A	0.562	0.41
235_R	265_E	0.562	0.41
269_Q	391_V	0.562	0.41
146_I	375_V	0.562	0.41
504_G	510_G	0.561	0.41
425_D	436_L	0.561	0.41
453_R	461_G	0.560	0.41
174_L	442_P	0.560	0.41
505_V	510_G	0.559	0.41
438_R	445_R	0.559	0.41
158_Y	356_S	0.559	0.41
335_L	338_G	0.559	0.41
103_S	141_S	0.558	0.41
34_G	166_R	0.558	0.41
456_H	467_E	0.558	0.41
338_G	341_E	0.557	0.41
315_E	339_R	0.556	0.41
256_V	263_L	0.553	0.40
185_S	265_E	0.553	0.40
185_S	379_L	0.553	0.40
14_F	168_L	0.553	0.40
186_K	317_T	0.552	0.40
195_K	330_E	0.552	0.40
309_E	324_Y	0.552	0.40
16_K	511_I	0.551	0.40
88_R	433_L	0.551	0.40
187_Y	191_I	0.551	0.40
229_S	366_T	0.551	0.40
443_L	447_Q	0.551	0.40
15_S	33_H	0.549	0.40
410_T	413_W	0.548	0.40
372_A	412_N	0.547	0.40
325_L	512_S	0.546	0.40
165_E	349_A	0.546	0.40
173_D	195_K	0.546	0.40
354_K	425_D	0.545	0.39
173_D	458_T	0.544	0.39
423_L	477_V	0.543	0.39
490_V	499_E	0.543	0.39
99_F	339_R	0.542	0.39
149_G	356_S	0.542	0.39
94_Y	98_V	0.542	0.39
39_V	44_R	0.541	0.39
491_D	494_R	0.541	0.39
154_D	413_W	0.541	0.39
38_V	217_L	0.540	0.39
415_G	429_F	0.540	0.39
232_T	335_L	0.538	0.39
398_D	458_T	0.538	0.39
24_F	66_R	0.537	0.39
446_S	449_H	0.537	0.39
227_S	429_F	0.536	0.39
231_V	262_N	0.536	0.39
192_Q	342_A	0.533	0.38
473_N	477_V	0.533	0.38
351_K	447_Q	0.533	0.38
427_T	446_S	0.533	0.38
407_P	410_T	0.532	0.38
377_Y	380_E	0.531	0.38
216_L	258_F	0.530	0.38
195_K	435_H	0.530	0.38
445_R	450_F	0.529	0.38
316_E	332_C	0.529	0.38
105_V	144_E	0.527	0.38
104_I	302_Y	0.527	0.38
458_T	470_E	0.527	0.38
312_V	318_R	0.527	0.38
43_E	100_M	0.526	0.37
171_S	414_V	0.525	0.37
270_T	463_I	0.525	0.37
251_E	257_K	0.525	0.37
243_E	290_Y	0.525	0.37
49_I	57_P	0.525	0.37
208_L	235_R	0.524	0.37
195_K	478_K	0.523	0.37
60_V	350_N	0.523	0.37
150_E	478_K	0.523	0.37
152_P	174_L	0.521	0.37
485_E	488_Q	0.521	0.37
228_I	325_L	0.518	0.37
139_G	264_E	0.518	0.37
296_N	302_Y	0.518	0.37
275_I	295_A	0.517	0.37
229_S	242_D	0.516	0.36
190_E	196_T	0.515	0.36
229_S	278_L	0.514	0.36
287_G	293_K	0.513	0.36
169_M	424_V	0.513	0.36
186_K	220_S	0.513	0.36
172_E	355_V	0.512	0.36
58_V	394_V	0.511	0.36
50_G	390_T	0.510	0.36
27_Y	61_E	0.509	0.36
437_R	454_D	0.509	0.36
18_R	359_L	0.508	0.36
192_Q	201_R	0.507	0.36
237_L	322_A	0.506	0.35
312_V	328_M	0.505	0.35
468_T	471_G	0.505	0.35
40_T	270_T	0.504	0.35
236_A	284_S	0.504	0.35
232_T	316_E	0.504	0.35
296_N	308_H	0.504	0.35
291_Q	304_L	0.504	0.35
23_H	443_L	0.503	0.35
71_R	74_E	0.502	0.35
440_R	477_V	0.502	0.35
329_A	506_E	0.502	0.35
142_D	371_L	0.502	0.35
413_W	419_G	0.501	0.35
484_M	507_G	0.500	0.35
139_G	245_I	0.500	0.35
305_P	431_G	0.500	0.35
35_M	228_I	0.500	0.35

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4qiwB	1	0.9579	100	0.099	Contact Map
4aybB	1	0.9656	100	0.107	Contact Map
1twfB	2	0.9082	100	0.109	Contact Map
3h0gB	1	0.9426	100	0.111	Contact Map
4c2mB	1	0.9751	100	0.145	Contact Map
2a6hC	1	0.8853	100	0.229	Contact Map
4yfkC	1	0.8967	100	0.24	Contact Map
4kbmA	1	0.6539	100	0.489	Contact Map
3mlqA	1	0.3384	100	0.746	Contact Map
3ltiA	1	0.2945	99.9	0.832	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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