GREMLIN Database
RPOB1 - DNA-directed RNA polymerase subunit B'
UniProt: P0CX03 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 608 (517)
Sequences: 2265 (832)
Seq/√Len: 36.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
212_A395_P7.7561.00
230_G396_D4.2531.00
101_E126_H4.2291.00
399_L403_A4.2231.00
210_V476_T3.8881.00
226_V398_V3.8361.00
174_R185_P3.8181.00
189_M422_G3.7931.00
213_V477_I3.7801.00
447_E453_S3.7441.00
103_I111_I3.6181.00
291_V297_L3.6041.00
367_F479_Y3.5381.00
550_C553_C3.4811.00
170_N207_Q3.4131.00
227_M361_P3.3431.00
241_F329_R3.2501.00
227_M377_V3.2491.00
591_D594_K3.1051.00
302_S324_T2.9391.00
280_D286_N2.8871.00
209_F237_S2.8661.00
586_F590_L2.8611.00
551_G578_H2.8301.00
120_L124_H2.8221.00
79_E85_K2.8191.00
224_A456_K2.8021.00
233_E383_Q2.7991.00
190_V419_G2.7931.00
444_G448_D2.7731.00
214_M472_I2.7191.00
389_T474_V2.7001.00
438_G441_E2.6561.00
226_V379_H2.6341.00
230_G234_R2.5981.00
416_M477_I2.5411.00
459_M474_V2.5061.00
458_V467_K2.4891.00
590_L600_P2.4381.00
67_L74_P2.4081.00
553_C571_C2.3791.00
291_V336_V2.3791.00
460_Y467_K2.3331.00
425_D449_R2.2990.99
458_V471_E2.2940.99
114_G120_L2.2510.99
232_V380_L2.2260.99
80_E99_K2.2060.99
359_R488_N2.1660.99
440_D444_G2.1620.99
395_P472_I2.1610.99
297_L336_V2.1320.99
70_E75_V2.1220.99
493_R496_G2.1100.99
292_D333_D2.1060.99
341_L349_K2.0850.99
420_K457_E2.0830.99
389_T393_V2.0780.99
422_G429_V2.0330.99
334_G355_V2.0260.99
445_T448_D2.0160.99
226_V381_A1.9620.98
245_Y355_V1.9610.98
215_S398_V1.9540.98
286_N289_T1.9510.98
231_S361_P1.9280.98
454_S471_E1.9150.98
446_L455_G1.9080.98
244_T352_K1.8540.97
230_G383_Q1.8220.97
217_E463_V1.8210.97
211_V477_I1.8080.97
421_A449_R1.8000.97
414_L417_L1.7990.97
211_V416_M1.7950.97
149_A155_M1.7950.97
540_D551_G1.7870.97
517_V537_R1.7820.97
278_H285_V1.7560.97
76_V99_K1.7280.96
423_S476_T1.7270.96
136_G139_A1.7220.96
135_F433_P1.7070.96
83_A89_I1.6960.96
249_E351_A1.6860.96
535_K540_D1.6650.95
341_L351_A1.6590.95
362_E487_S1.6500.95
316_L319_Q1.6430.95
158_G161_K1.6300.95
377_V398_V1.6190.94
359_R485_M1.6100.94
151_P155_M1.6070.94
343_E495_K1.5950.94
421_A425_D1.5860.94
485_M488_N1.5800.94
237_S367_F1.5760.94
72_G84_V1.5740.94
77_T85_K1.5700.94
261_E301_T1.5650.93
150_S155_M1.5610.93
328_M355_V1.5470.93
444_G447_E1.5460.93
80_E84_V1.5320.93
311_E314_G1.5240.92
89_I97_A1.5190.92
420_K451_F1.5170.92
183_H240_H1.5160.92
252_Y258_D1.5060.92
111_I125_T1.5060.92
368_A412_H1.5040.92
337_D356_R1.5010.92
149_A156_G1.4960.92
414_L439_E1.4960.92
149_A153_I1.4810.91
82_E85_K1.4690.91
83_A88_D1.4470.90
298_L326_V1.4300.90
209_F231_S1.4270.90
82_E87_G1.4100.89
594_K600_P1.4100.89
390_Q457_E1.4050.89
212_A472_I1.3930.89
213_V416_M1.3890.88
481_K596_L1.3790.88
212_A459_M1.3710.88
68_V336_V1.3670.88
214_M397_L1.3670.88
237_S361_P1.3670.88
82_E86_N1.3620.87
247_G298_L1.3500.87
391_E451_F1.3450.87
570_N578_H1.3430.87
388_F460_Y1.3220.86
503_R584_Y1.3070.85
141_M203_R1.2730.84
260_F284_L1.2730.84
167_P368_A1.2710.83
395_P398_V1.2690.83
446_L451_F1.2680.83
359_R411_G1.2660.83
362_E380_L1.2590.83
238_R360_I1.2530.83
142_I189_M1.2510.82
313_M316_L1.2480.82
239_S481_K1.2470.82
104_D308_E1.2410.82
357_D456_K1.2390.82
287_P339_V1.2390.82
346_D398_V1.2370.82
134_I582_M1.2370.82
389_T459_M1.2350.82
101_E107_E1.2290.81
105_A384_E1.2270.81
417_L473_F1.2260.81
477_I480_H1.2240.81
153_I156_G1.2130.80
536_E541_S1.2070.80
544_R581_E1.2040.80
414_L418_G1.2020.80
308_E319_Q1.1980.80
247_G326_V1.1920.79
210_V389_T1.1890.79
546_E579_S1.1890.79
207_Q236_L1.1860.79
436_G439_E1.1780.78
81_V85_K1.1740.78
139_A352_K1.1740.78
67_L127_L1.1740.78
220_N299_G1.1730.78
439_E443_R1.1680.78
106_E348_S1.1650.78
458_V472_I1.1630.78
260_F263_P1.1580.77
91_F94_L1.1550.77
355_V517_V1.1440.76
139_A217_E1.1380.76
443_R454_S1.1370.76
586_F602_L1.1340.76
297_L474_V1.1330.76
154_T158_G1.1290.75
408_M508_G1.1240.75
383_Q394_V1.1180.75
69_V74_P1.1180.75
231_S236_L1.1170.75
90_D101_E1.1150.74
67_L76_V1.1150.74
159_M408_M1.1100.74
284_L459_M1.1050.74
94_L97_A1.1020.74
229_K233_E1.1000.73
148_N411_G1.0980.73
209_F397_L1.0980.73
480_H537_R1.0950.73
73_E82_E1.0950.73
418_G442_I1.0850.72
224_A525_V1.0810.72
221_I224_A1.0800.72
231_S587_K1.0740.72
209_F236_L1.0730.72
501_L595_A1.0730.72
159_M406_S1.0670.71
120_L127_L1.0670.71
111_I126_H1.0660.71
493_R514_G1.0610.71
491_H507_E1.0570.70
253_P305_R1.0560.70
159_M516_R1.0560.70
499_Q506_T1.0530.70
228_N383_Q1.0520.70
549_V553_C1.0510.70
522_R526_I1.0510.70
121_T124_H1.0510.70
537_R571_C1.0500.70
299_G325_S1.0480.70
476_T490_L1.0460.70
116_E119_E1.0440.69
309_E320_K1.0380.69
274_D277_T1.0310.68
252_Y255_G1.0290.68
156_G160_M1.0250.68
508_G516_R1.0250.68
79_E83_A1.0170.67
308_E346_D1.0120.67
347_G350_L1.0090.67
411_G415_E1.0070.67
68_V83_A1.0070.67
549_V587_K1.0040.66
287_P338_T1.0020.66
416_M473_F0.9970.66
589_L593_M0.9950.66
410_V454_S0.9950.66
517_V538_L0.9930.66
305_R312_D0.9920.65
370_R516_R0.9810.65
278_H289_T0.9800.64
255_G324_T0.9760.64
219_F405_P0.9720.64
553_C573_E0.9710.64
76_V80_E0.9710.64
78_Q82_E0.9690.64
156_G480_H0.9690.64
73_E86_N0.9660.63
403_A422_G0.9610.63
485_M528_H0.9610.63
106_E456_K0.9570.63
93_D593_M0.9540.62
290_K333_D0.9530.62
69_V73_E0.9520.62
408_M516_R0.9520.62
155_M159_M0.9500.62
472_I478_F0.9470.62
139_A319_Q0.9460.62
73_E77_T0.9450.62
398_V476_T0.9440.62
100_V187_K0.9420.61
70_E73_E0.9410.61
90_D99_K0.9370.61
69_V405_P0.9360.61
212_A398_V0.9320.61
442_I445_T0.9310.60
278_H286_N0.9310.60
359_R553_C0.9270.60
367_F501_L0.9260.60
367_F426_G0.9240.60
436_G441_E0.9240.60
225_L479_Y0.9230.60
550_C571_C0.9210.60
124_H397_L0.9210.60
355_V388_F0.9190.59
144_Y326_V0.9160.59
211_V395_P0.9140.59
66_L417_L0.9130.59
361_P420_K0.9130.59
182_L595_A0.9120.59
202_D494_S0.9090.59
278_H295_S0.9090.59
77_T80_E0.9080.59
540_D544_R0.9040.58
361_P479_Y0.9030.58
291_V328_M0.9020.58
320_K549_V0.9010.58
351_A472_I0.9010.58
221_I237_S0.9000.58
216_Y463_V0.9000.58
379_H385_D0.8970.58
74_P148_N0.8960.57
332_E485_M0.8940.57
126_H234_R0.8920.57
284_L351_A0.8880.57
79_E89_I0.8860.57
209_F396_D0.8850.57
83_A86_N0.8830.56
139_A157_A0.8800.56
284_L341_L0.8790.56
431_G437_E0.8760.56
497_P536_E0.8750.56
232_V291_V0.8740.56
437_E442_I0.8740.56
516_R519_E0.8730.55
337_D533_V0.8730.55
370_R508_G0.8720.55
233_E282_D0.8710.55
255_G259_R0.8710.55
150_S485_M0.8700.55
282_D339_V0.8680.55
372_G415_E0.8680.55
412_H419_G0.8680.55
367_F400_N0.8670.55
545_E591_D0.8660.55
210_V393_V0.8650.55
232_V397_L0.8620.55
450_G457_E0.8580.54
245_Y332_E0.8540.54
279_L393_V0.8530.54
313_M317_S0.8530.54
144_Y377_V0.8530.54
368_A399_L0.8500.53
525_V536_E0.8470.53
90_D126_H0.8430.53
437_E441_E0.8420.53
370_R408_M0.8350.52
159_M508_G0.8350.52
451_F574_E0.8330.52
187_K353_V0.8330.52
301_T323_E0.8300.52
586_F600_P0.8300.52
422_G445_T0.8300.52
141_M215_S0.8260.51
231_S485_M0.8250.51
163_S353_V0.8230.51
255_G303_P0.8220.51
69_V358_E0.8210.51
100_V123_D0.8200.51
214_M244_T0.8200.51
82_E88_D0.8190.51
211_V478_F0.8180.51
551_G577_V0.8160.51
395_P479_Y0.8160.51
241_F299_G0.8110.50
316_L321_R0.8100.50
359_R397_L0.8100.50
371_H411_G0.8090.50
148_N415_E0.8090.50
114_G127_L0.8070.50
158_G399_L0.8060.50
298_L351_A0.8050.50
175_P340_T0.8040.49
69_V284_L0.8040.49
157_A220_N0.8040.49
168_A309_E0.7990.49
102_F398_V0.7980.49
79_E82_E0.7980.49
180_H239_S0.7980.49
224_A248_E0.7960.49
490_L509_R0.7950.49
359_R511_R0.7940.49
226_V367_F0.7940.49
399_L412_H0.7930.49
496_G514_G0.7910.48
299_G323_E0.7890.48
232_V248_E0.7870.48
429_V445_T0.7850.48
245_Y546_E0.7840.48
587_K591_D0.7840.48
301_T321_R0.7820.48
66_L103_I0.7810.47
150_S153_I0.7760.47
103_I126_H0.7760.47
328_M331_G0.7750.47
235_A360_I0.7740.47
117_E127_L0.7740.47
410_V470_A0.7740.47
137_I413_V0.7740.47
204_P386_M0.7730.47
163_S207_Q0.7720.47
372_G411_G0.7720.47
243_R446_L0.7710.47
142_I145_P0.7700.46
291_V295_S0.7660.46
453_S471_E0.7660.46
169_A207_Q0.7650.46
370_R415_E0.7650.46
251_R274_D0.7630.46
511_R526_I0.7620.46
255_G262_I0.7600.46
96_E120_L0.7600.46
76_V82_E0.7590.46
234_R479_Y0.7580.45
361_P367_F0.7580.45
501_L601_R0.7570.45
178_R328_M0.7560.45
142_I147_H0.7560.45
479_Y587_K0.7560.45
307_L310_P0.7530.45
186_Q345_E0.7510.45
151_P159_M0.7510.45
151_P434_F0.7500.45
248_E350_L0.7480.45
491_H510_A0.7480.45
428_S448_D0.7470.44
112_L127_L0.7460.44
446_L537_R0.7460.44
444_G454_S0.7450.44
249_E272_G0.7430.44
225_L367_F0.7430.44
414_L442_I0.7430.44
425_D451_F0.7420.44
495_K512_E0.7420.44
226_V485_M0.7410.44
417_L477_I0.7400.44
224_A422_G0.7380.44
486_V502_T0.7380.44
123_D126_H0.7370.44
116_E527_G0.7340.43
353_V511_R0.7340.43
304_P344_G0.7330.43
287_P527_G0.7310.43
109_E126_H0.7300.43
118_E127_L0.7300.43
525_V534_L0.7290.43
525_V537_R0.7270.43
398_V473_F0.7260.43
89_I128_E0.7240.43
217_E226_V0.7190.42
537_R553_C0.7180.42
495_K499_Q0.7170.42
436_G443_R0.7170.42
400_N413_V0.7150.42
206_G519_E0.7150.42
74_P77_T0.7130.42
403_A416_M0.7110.41
322_R346_D0.7100.41
447_E452_K0.7080.41
134_I525_V0.7070.41
518_G521_E0.7060.41
71_N82_E0.7060.41
215_S221_I0.7040.41
282_D349_K0.7040.41
215_S220_N0.7030.41
489_K493_R0.7020.41
449_R452_K0.7010.41
138_G537_R0.7000.40
357_D483_Y0.6980.40
383_Q396_D0.6970.40
552_N576_D0.6970.40
373_Q409_T0.6960.40
251_R312_D0.6960.40
80_E93_D0.6960.40
508_G513_G0.6950.40
416_M475_G0.6950.40
484_H489_K0.6950.40
139_A510_A0.6940.40
139_A386_M0.6940.40
450_G460_Y0.6940.40
215_S443_R0.6930.40
296_V327_T0.6930.40
473_F477_I0.6920.40
291_V334_G0.6920.40
116_E120_L0.6910.40
299_G334_G0.6900.40
545_E584_Y0.6890.40
413_V416_M0.6870.39
537_R550_C0.6870.39
290_K335_V0.6870.39
390_Q460_Y0.6860.39
509_R528_H0.6850.39
129_I336_V0.6850.39
96_E474_V0.6850.39
137_I517_V0.6810.39
254_G510_A0.6810.39
212_A396_D0.6800.39
84_V233_E0.6800.39
112_L123_D0.6790.39
186_Q411_G0.6780.39
177_T243_R0.6770.39
139_A243_R0.6760.38
368_A371_H0.6740.38
254_G276_Y0.6720.38
102_F106_E0.6710.38
216_Y470_A0.6700.38
166_L239_S0.6690.38
326_V329_R0.6690.38
214_M476_T0.6680.38
114_G485_M0.6680.38
136_G180_H0.6680.38
185_P537_R0.6670.38
71_N598_I0.6660.38
211_V236_L0.6660.38
92_E97_A0.6660.38
248_E351_A0.6640.37
271_R320_K0.6630.37
193_Q385_D0.6620.37
162_Q484_H0.6620.37
146_E220_N0.6620.37
220_N405_P0.6620.37
332_E587_K0.6610.37
490_L588_L0.6600.37
198_I574_E0.6590.37
224_A308_E0.6570.37
154_T524_T0.6560.37
377_V459_M0.6560.37
472_I494_S0.6560.37
376_V414_L0.6560.37
483_Y587_K0.6550.37
287_P431_G0.6550.37
106_E591_D0.6550.37
159_M486_V0.6550.37
584_Y591_D0.6550.37
95_V100_V0.6550.37
442_I454_S0.6530.37
230_G384_E0.6530.37
148_N372_G0.6510.36
166_L404_L0.6500.36
75_V85_K0.6500.36
357_D499_Q0.6500.36
249_E348_S0.6490.36
343_E347_G0.6490.36
78_Q81_V0.6490.36
252_Y506_T0.6480.36
408_M491_H0.6480.36
421_A424_L0.6470.36
298_L382_P0.6450.36
399_L404_L0.6440.36
251_R256_Q0.6430.36
149_A209_F0.6420.36
497_P512_E0.6410.36
501_L584_Y0.6400.36
390_Q458_V0.6390.35
535_K580_I0.6390.35
337_D367_F0.6390.35
159_M370_R0.6380.35
369_S480_H0.6380.35
209_F577_V0.6370.35
211_V479_Y0.6360.35
129_I287_P0.6350.35
403_A484_H0.6350.35
109_E249_E0.6340.35
150_S156_G0.6340.35
240_H356_R0.6330.35
173_I176_D0.6310.35
460_Y471_E0.6310.35
327_T576_D0.6310.35
397_L419_G0.6310.35
151_P420_K0.6290.35
224_A359_R0.6280.35
296_V323_E0.6270.34
157_A597_G0.6270.34
256_Q262_I0.6270.34
410_V445_T0.6260.34
416_M420_K0.6260.34
427_R445_T0.6250.34
150_S225_L0.6250.34
119_E127_L0.6250.34
384_E398_V0.6240.34
135_F145_P0.6230.34
420_K446_L0.6230.34
149_A409_T0.6220.34
68_V105_A0.6220.34
71_N437_E0.6220.34
522_R537_R0.6210.34
333_D357_D0.6200.34
484_H493_R0.6190.34
525_V533_V0.6190.34
179_Q354_S0.6180.34
370_R491_H0.6180.34
259_R264_G0.6160.34
229_K380_L0.6150.34
297_L328_M0.6150.34
143_P542_S0.6140.33
323_E439_E0.6130.33
76_V84_V0.6120.33
113_V131_P0.6120.33
224_A570_N0.6120.33
213_V481_K0.6110.33
285_V353_V0.6110.33
579_S595_A0.6110.33
232_V361_P0.6110.33
504_Q513_G0.6100.33
98_G114_G0.6100.33
527_G532_M0.6100.33
215_S335_V0.6090.33
396_D476_T0.6080.33
456_K470_A0.6080.33
220_N404_L0.6060.33
592_E596_L0.6050.33
300_K481_K0.6040.33
190_V472_I0.6040.33
355_V363_L0.6040.33
76_V86_N0.6040.33
301_T597_G0.6030.33
191_N196_E0.6030.33
145_P205_A0.6020.33
213_V369_S0.6000.32
251_R281_D0.5990.32
153_I480_H0.5980.32
537_R551_G0.5980.32
215_S477_I0.5960.32
77_T89_I0.5960.32
335_V527_G0.5950.32
102_F114_G0.5950.32
497_P502_T0.5940.32
148_N507_E0.5940.32
531_A577_V0.5940.32
335_V390_Q0.5940.32
530_A538_L0.5930.32
110_D351_A0.5920.32
133_L144_Y0.5920.32
576_D601_R0.5910.32
225_L379_H0.5910.32
585_A592_E0.5910.32
164_L182_L0.5910.32
549_V604_L0.5910.32
426_G450_G0.5910.32
427_R437_E0.5910.32
67_L87_G0.5900.32
224_A363_L0.5890.32
226_V439_E0.5880.31
281_D574_E0.5870.31
361_P485_M0.5850.31
224_A485_M0.5840.31
134_I154_T0.5830.31
240_H459_M0.5830.31
253_P322_R0.5830.31
296_V414_L0.5820.31
491_H508_G0.5820.31
109_E400_N0.5810.31
417_L429_V0.5810.31
169_A202_D0.5810.31
66_L128_E0.5800.31
122_T281_D0.5800.31
213_V233_E0.5800.31
196_E451_F0.5800.31
229_K382_P0.5790.31
295_S336_V0.5750.30
451_F457_E0.5740.30
199_G397_L0.5740.30
104_D136_G0.5730.30
311_E319_Q0.5720.30
188_A359_R0.5720.30
548_H579_S0.5710.30
144_Y411_G0.5710.30
80_E426_G0.5690.30
504_Q508_G0.5680.30
155_M160_M0.5680.30
75_V86_N0.5670.30
161_K399_L0.5660.30
339_V595_A0.5660.30
157_A412_H0.5650.30
589_L592_E0.5650.30
149_A159_M0.5650.30
216_Y399_L0.5630.30
309_E423_S0.5630.30
300_K303_P0.5630.30
450_G485_M0.5620.30
301_T602_L0.5620.30
479_Y483_Y0.5620.30
505_P542_S0.5610.29
171_Y287_P0.5600.29
115_V118_E0.5590.29
436_G444_G0.5590.29
156_G541_S0.5590.29
74_P82_E0.5580.29
297_L326_V0.5570.29
316_L511_R0.5550.29
517_V525_V0.5550.29
178_R184_Y0.5550.29
210_V395_P0.5540.29
103_I248_E0.5530.29
143_P371_H0.5520.29
378_G420_K0.5520.29
69_V109_E0.5510.29
162_Q519_E0.5510.29
529_G543_D0.5490.29
373_Q523_D0.5480.29
104_D587_K0.5480.29
326_V353_V0.5470.28
74_P196_E0.5450.28
93_D96_E0.5450.28
338_T393_V0.5450.28
85_K318_P0.5450.28
286_N295_S0.5440.28
146_E149_A0.5440.28
76_V81_V0.5440.28
140_G171_Y0.5430.28
231_S386_M0.5410.28
69_V127_L0.5410.28
107_E189_M0.5400.28
319_Q324_T0.5400.28
97_A447_E0.5400.28
119_E144_Y0.5400.28
224_A237_S0.5400.28
79_E87_G0.5400.28
389_T421_A0.5400.28
73_E340_T0.5400.28
252_Y257_E0.5380.28
357_D396_D0.5380.28
342_M517_V0.5370.28
405_P434_F0.5360.28
395_P459_M0.5360.28
75_V309_E0.5350.28
324_T339_V0.5350.28
347_G577_V0.5340.28
224_A486_V0.5330.27
473_F485_M0.5320.27
220_N412_H0.5320.27
281_D580_I0.5310.27
123_D244_T0.5310.27
171_Y227_M0.5300.27
93_D97_A0.5300.27
273_E293_D0.5300.27
491_H509_R0.5290.27
135_F189_M0.5290.27
124_H258_D0.5280.27
491_H515_L0.5280.27
134_I580_I0.5280.27
376_V528_H0.5270.27
163_S442_I0.5270.27
112_L125_T0.5260.27
362_E490_L0.5260.27
397_L582_M0.5260.27
282_D308_E0.5240.27
262_I271_R0.5240.27
260_F466_E0.5220.27
261_E321_R0.5220.27
308_E577_V0.5220.27
83_A87_G0.5210.27
494_S578_H0.5210.27
224_A357_D0.5200.27
234_R395_P0.5200.27
545_E590_L0.5190.26
119_E388_F0.5190.26
344_G572_E0.5180.26
184_Y473_F0.5180.26
450_G537_R0.5180.26
397_L428_S0.5170.26
347_G470_A0.5170.26
81_V198_I0.5170.26
284_L298_L0.5170.26
247_G576_D0.5160.26
590_L602_L0.5160.26
548_H577_V0.5160.26
294_S324_T0.5150.26
104_D125_T0.5150.26
413_V455_G0.5140.26
168_A207_Q0.5140.26
253_P258_D0.5140.26
248_E597_G0.5130.26
128_E550_C0.5110.26
138_G294_S0.5110.26
91_F479_Y0.5110.26
418_G429_V0.5110.26
403_A456_K0.5100.26
188_A472_I0.5090.26
294_S423_S0.5080.26
147_H378_G0.5080.26
255_G344_G0.5070.26
163_S417_L0.5070.26
253_P257_E0.5070.26
192_T457_E0.5060.26
90_D97_A0.5050.26
593_M603_E0.5050.26
272_G277_T0.5040.25
593_M600_P0.5040.25
315_G319_Q0.5030.25
73_E79_E0.5030.25
352_K591_D0.5030.25
243_R329_R0.5030.25
347_G377_V0.5020.25
224_A350_L0.5020.25
254_G261_E0.5020.25
504_Q514_G0.5010.25
147_H531_A0.5010.25
410_V490_L0.5010.25
388_F453_S0.5010.25
85_K340_T0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1twfB 2 0.9507 100 0.023 Contact Map
3h0gB 1 0.9803 100 0.025 Contact Map
4qiwB 1 0.9375 100 0.027 Contact Map
4aybB 1 0.9786 100 0.032 Contact Map
4c2mB 1 0.9227 100 0.132 Contact Map
2a6hC 1 0.9605 100 0.187 Contact Map
4yfkC 1 0.9556 100 0.203 Contact Map
2ly7A 1 0.2056 100 0.874 Contact Map
3woeA 1 0.1891 99.8 0.906 Contact Map
3tbiB 1 0.227 99.8 0.916 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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