RPOB1 - HALSA - GREMLIN Contacts

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RPOB1 - DNA-directed RNA polymerase subunit B'

UniProt:	P0CX03	Sequences: MSTEREAKVYVNGSLVGTHENPEELAEQIREARRRGEVSEMVNVSVRDRTGEVIVNADAGRARRPLLVVENGEPVVTQEEVEAVKNGDIDFEDLVEAGKVEFIDAEEEEDILVGVEEEELTTDHTHLEIDPQLIFGIGAGMIPYPEHNASPRITMGAGMMKQSLGLPAANYRIRPDTRQHLLHYPQKAMVNTQTTEQIGYDDRPAGQNFVVAVMSYEGFNIEDALVMNKGSVERALSRSHFFRTYEGEERRYPGGQEDRFEIPGDDVRGARGEDAYTHLDDDGLVNPETKVDDSSVLLGKTSPPRFLEEPEDMGGLSPQKRRETSVTMRSGEDGVVDTVTLMEGEDGSKLAKVSVRDERIPELGDKFASRHGQKGVVGHLAPQEDMPFTQEGVVPDLVLNPHALPSRMTVGHVLEMLGGKAGSLDGRSVDGTPFTGEGEDEIRGTLEDRGFKSSGKEVMYSGVSGEKIEAEIFVGTIFYHKLYHMVSNKLHARSKGPVQVLTRQPTEGRAREGGLRVGEMERDTVIGHGAAMVLKERLLDSSDREEIHVCGNCGMTAVENYEQRRVYCPNCEEETDVHSIEMSYAFKLLLDEMKALGIAPRLELEEAV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	608 (517)
Sequences:	2265 (832)
Seq/√Len:	36.6

ECOLI - RPOB
BACSU - RPOB
HALSA - RPOB1
SULSO - Q980R1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
212_A	395_P	7.756	1.00
230_G	396_D	4.253	1.00
101_E	126_H	4.229	1.00
399_L	403_A	4.223	1.00
210_V	476_T	3.888	1.00
226_V	398_V	3.836	1.00
174_R	185_P	3.818	1.00
189_M	422_G	3.793	1.00
213_V	477_I	3.780	1.00
447_E	453_S	3.744	1.00
103_I	111_I	3.618	1.00
291_V	297_L	3.604	1.00
367_F	479_Y	3.538	1.00
550_C	553_C	3.481	1.00
170_N	207_Q	3.413	1.00
227_M	361_P	3.343	1.00
241_F	329_R	3.250	1.00
227_M	377_V	3.249	1.00
591_D	594_K	3.105	1.00
302_S	324_T	2.939	1.00
280_D	286_N	2.887	1.00
209_F	237_S	2.866	1.00
586_F	590_L	2.861	1.00
551_G	578_H	2.830	1.00
120_L	124_H	2.822	1.00
79_E	85_K	2.819	1.00
224_A	456_K	2.802	1.00
233_E	383_Q	2.799	1.00
190_V	419_G	2.793	1.00
444_G	448_D	2.773	1.00
214_M	472_I	2.719	1.00
389_T	474_V	2.700	1.00
438_G	441_E	2.656	1.00
226_V	379_H	2.634	1.00
230_G	234_R	2.598	1.00
416_M	477_I	2.541	1.00
459_M	474_V	2.506	1.00
458_V	467_K	2.489	1.00
590_L	600_P	2.438	1.00
67_L	74_P	2.408	1.00
553_C	571_C	2.379	1.00
291_V	336_V	2.379	1.00
460_Y	467_K	2.333	1.00
425_D	449_R	2.299	0.99
458_V	471_E	2.294	0.99
114_G	120_L	2.251	0.99
232_V	380_L	2.226	0.99
80_E	99_K	2.206	0.99
359_R	488_N	2.166	0.99
440_D	444_G	2.162	0.99
395_P	472_I	2.161	0.99
297_L	336_V	2.132	0.99
70_E	75_V	2.122	0.99
493_R	496_G	2.110	0.99
292_D	333_D	2.106	0.99
341_L	349_K	2.085	0.99
420_K	457_E	2.083	0.99
389_T	393_V	2.078	0.99
422_G	429_V	2.033	0.99
334_G	355_V	2.026	0.99
445_T	448_D	2.016	0.99
226_V	381_A	1.962	0.98
245_Y	355_V	1.961	0.98
215_S	398_V	1.954	0.98
286_N	289_T	1.951	0.98
231_S	361_P	1.928	0.98
454_S	471_E	1.915	0.98
446_L	455_G	1.908	0.98
244_T	352_K	1.854	0.97
230_G	383_Q	1.822	0.97
217_E	463_V	1.821	0.97
211_V	477_I	1.808	0.97
421_A	449_R	1.800	0.97
414_L	417_L	1.799	0.97
211_V	416_M	1.795	0.97
149_A	155_M	1.795	0.97
540_D	551_G	1.787	0.97
517_V	537_R	1.782	0.97
278_H	285_V	1.756	0.97
76_V	99_K	1.728	0.96
423_S	476_T	1.727	0.96
136_G	139_A	1.722	0.96
135_F	433_P	1.707	0.96
83_A	89_I	1.696	0.96
249_E	351_A	1.686	0.96
535_K	540_D	1.665	0.95
341_L	351_A	1.659	0.95
362_E	487_S	1.650	0.95
316_L	319_Q	1.643	0.95
158_G	161_K	1.630	0.95
377_V	398_V	1.619	0.94
359_R	485_M	1.610	0.94
151_P	155_M	1.607	0.94
343_E	495_K	1.595	0.94
421_A	425_D	1.586	0.94
485_M	488_N	1.580	0.94
237_S	367_F	1.576	0.94
72_G	84_V	1.574	0.94
77_T	85_K	1.570	0.94
261_E	301_T	1.565	0.93
150_S	155_M	1.561	0.93
328_M	355_V	1.547	0.93
444_G	447_E	1.546	0.93
80_E	84_V	1.532	0.93
311_E	314_G	1.524	0.92
89_I	97_A	1.519	0.92
420_K	451_F	1.517	0.92
183_H	240_H	1.516	0.92
252_Y	258_D	1.506	0.92
111_I	125_T	1.506	0.92
368_A	412_H	1.504	0.92
337_D	356_R	1.501	0.92
149_A	156_G	1.496	0.92
414_L	439_E	1.496	0.92
149_A	153_I	1.481	0.91
82_E	85_K	1.469	0.91
83_A	88_D	1.447	0.90
298_L	326_V	1.430	0.90
209_F	231_S	1.427	0.90
82_E	87_G	1.410	0.89
594_K	600_P	1.410	0.89
390_Q	457_E	1.405	0.89
212_A	472_I	1.393	0.89
213_V	416_M	1.389	0.88
481_K	596_L	1.379	0.88
212_A	459_M	1.371	0.88
68_V	336_V	1.367	0.88
214_M	397_L	1.367	0.88
237_S	361_P	1.367	0.88
82_E	86_N	1.362	0.87
247_G	298_L	1.350	0.87
391_E	451_F	1.345	0.87
570_N	578_H	1.343	0.87
388_F	460_Y	1.322	0.86
503_R	584_Y	1.307	0.85
141_M	203_R	1.273	0.84
260_F	284_L	1.273	0.84
167_P	368_A	1.271	0.83
395_P	398_V	1.269	0.83
446_L	451_F	1.268	0.83
359_R	411_G	1.266	0.83
362_E	380_L	1.259	0.83
238_R	360_I	1.253	0.83
142_I	189_M	1.251	0.82
313_M	316_L	1.248	0.82
239_S	481_K	1.247	0.82
104_D	308_E	1.241	0.82
357_D	456_K	1.239	0.82
287_P	339_V	1.239	0.82
346_D	398_V	1.237	0.82
134_I	582_M	1.237	0.82
389_T	459_M	1.235	0.82
101_E	107_E	1.229	0.81
105_A	384_E	1.227	0.81
417_L	473_F	1.226	0.81
477_I	480_H	1.224	0.81
153_I	156_G	1.213	0.80
536_E	541_S	1.207	0.80
544_R	581_E	1.204	0.80
414_L	418_G	1.202	0.80
308_E	319_Q	1.198	0.80
247_G	326_V	1.192	0.79
210_V	389_T	1.189	0.79
546_E	579_S	1.189	0.79
207_Q	236_L	1.186	0.79
436_G	439_E	1.178	0.78
81_V	85_K	1.174	0.78
139_A	352_K	1.174	0.78
67_L	127_L	1.174	0.78
220_N	299_G	1.173	0.78
439_E	443_R	1.168	0.78
106_E	348_S	1.165	0.78
458_V	472_I	1.163	0.78
260_F	263_P	1.158	0.77
91_F	94_L	1.155	0.77
355_V	517_V	1.144	0.76
139_A	217_E	1.138	0.76
443_R	454_S	1.137	0.76
586_F	602_L	1.134	0.76
297_L	474_V	1.133	0.76
154_T	158_G	1.129	0.75
408_M	508_G	1.124	0.75
383_Q	394_V	1.118	0.75
69_V	74_P	1.118	0.75
231_S	236_L	1.117	0.75
90_D	101_E	1.115	0.74
67_L	76_V	1.115	0.74
159_M	408_M	1.110	0.74
284_L	459_M	1.105	0.74
94_L	97_A	1.102	0.74
229_K	233_E	1.100	0.73
148_N	411_G	1.098	0.73
209_F	397_L	1.098	0.73
480_H	537_R	1.095	0.73
73_E	82_E	1.095	0.73
418_G	442_I	1.085	0.72
224_A	525_V	1.081	0.72
221_I	224_A	1.080	0.72
231_S	587_K	1.074	0.72
209_F	236_L	1.073	0.72
501_L	595_A	1.073	0.72
159_M	406_S	1.067	0.71
120_L	127_L	1.067	0.71
111_I	126_H	1.066	0.71
493_R	514_G	1.061	0.71
491_H	507_E	1.057	0.70
253_P	305_R	1.056	0.70
159_M	516_R	1.056	0.70
499_Q	506_T	1.053	0.70
228_N	383_Q	1.052	0.70
549_V	553_C	1.051	0.70
522_R	526_I	1.051	0.70
121_T	124_H	1.051	0.70
537_R	571_C	1.050	0.70
299_G	325_S	1.048	0.70
476_T	490_L	1.046	0.70
116_E	119_E	1.044	0.69
309_E	320_K	1.038	0.69
274_D	277_T	1.031	0.68
252_Y	255_G	1.029	0.68
156_G	160_M	1.025	0.68
508_G	516_R	1.025	0.68
79_E	83_A	1.017	0.67
308_E	346_D	1.012	0.67
347_G	350_L	1.009	0.67
411_G	415_E	1.007	0.67
68_V	83_A	1.007	0.67
549_V	587_K	1.004	0.66
287_P	338_T	1.002	0.66
416_M	473_F	0.997	0.66
589_L	593_M	0.995	0.66
410_V	454_S	0.995	0.66
517_V	538_L	0.993	0.66
305_R	312_D	0.992	0.65
370_R	516_R	0.981	0.65
278_H	289_T	0.980	0.64
255_G	324_T	0.976	0.64
219_F	405_P	0.972	0.64
553_C	573_E	0.971	0.64
76_V	80_E	0.971	0.64
78_Q	82_E	0.969	0.64
156_G	480_H	0.969	0.64
73_E	86_N	0.966	0.63
403_A	422_G	0.961	0.63
485_M	528_H	0.961	0.63
106_E	456_K	0.957	0.63
93_D	593_M	0.954	0.62
290_K	333_D	0.953	0.62
69_V	73_E	0.952	0.62
408_M	516_R	0.952	0.62
155_M	159_M	0.950	0.62
472_I	478_F	0.947	0.62
139_A	319_Q	0.946	0.62
73_E	77_T	0.945	0.62
398_V	476_T	0.944	0.62
100_V	187_K	0.942	0.61
70_E	73_E	0.941	0.61
90_D	99_K	0.937	0.61
69_V	405_P	0.936	0.61
212_A	398_V	0.932	0.61
442_I	445_T	0.931	0.60
278_H	286_N	0.931	0.60
359_R	553_C	0.927	0.60
367_F	501_L	0.926	0.60
367_F	426_G	0.924	0.60
436_G	441_E	0.924	0.60
225_L	479_Y	0.923	0.60
550_C	571_C	0.921	0.60
124_H	397_L	0.921	0.60
355_V	388_F	0.919	0.59
144_Y	326_V	0.916	0.59
211_V	395_P	0.914	0.59
66_L	417_L	0.913	0.59
361_P	420_K	0.913	0.59
182_L	595_A	0.912	0.59
202_D	494_S	0.909	0.59
278_H	295_S	0.909	0.59
77_T	80_E	0.908	0.59
540_D	544_R	0.904	0.58
361_P	479_Y	0.903	0.58
291_V	328_M	0.902	0.58
320_K	549_V	0.901	0.58
351_A	472_I	0.901	0.58
221_I	237_S	0.900	0.58
216_Y	463_V	0.900	0.58
379_H	385_D	0.897	0.58
74_P	148_N	0.896	0.57
332_E	485_M	0.894	0.57
126_H	234_R	0.892	0.57
284_L	351_A	0.888	0.57
79_E	89_I	0.886	0.57
209_F	396_D	0.885	0.57
83_A	86_N	0.883	0.56
139_A	157_A	0.880	0.56
284_L	341_L	0.879	0.56
431_G	437_E	0.876	0.56
497_P	536_E	0.875	0.56
232_V	291_V	0.874	0.56
437_E	442_I	0.874	0.56
516_R	519_E	0.873	0.55
337_D	533_V	0.873	0.55
370_R	508_G	0.872	0.55
233_E	282_D	0.871	0.55
255_G	259_R	0.871	0.55
150_S	485_M	0.870	0.55
282_D	339_V	0.868	0.55
372_G	415_E	0.868	0.55
412_H	419_G	0.868	0.55
367_F	400_N	0.867	0.55
545_E	591_D	0.866	0.55
210_V	393_V	0.865	0.55
232_V	397_L	0.862	0.55
450_G	457_E	0.858	0.54
245_Y	332_E	0.854	0.54
279_L	393_V	0.853	0.54
313_M	317_S	0.853	0.54
144_Y	377_V	0.853	0.54
368_A	399_L	0.850	0.53
525_V	536_E	0.847	0.53
90_D	126_H	0.843	0.53
437_E	441_E	0.842	0.53
370_R	408_M	0.835	0.52
159_M	508_G	0.835	0.52
451_F	574_E	0.833	0.52
187_K	353_V	0.833	0.52
301_T	323_E	0.830	0.52
586_F	600_P	0.830	0.52
422_G	445_T	0.830	0.52
141_M	215_S	0.826	0.51
231_S	485_M	0.825	0.51
163_S	353_V	0.823	0.51
255_G	303_P	0.822	0.51
69_V	358_E	0.821	0.51
100_V	123_D	0.820	0.51
214_M	244_T	0.820	0.51
82_E	88_D	0.819	0.51
211_V	478_F	0.818	0.51
551_G	577_V	0.816	0.51
395_P	479_Y	0.816	0.51
241_F	299_G	0.811	0.50
316_L	321_R	0.810	0.50
359_R	397_L	0.810	0.50
371_H	411_G	0.809	0.50
148_N	415_E	0.809	0.50
114_G	127_L	0.807	0.50
158_G	399_L	0.806	0.50
298_L	351_A	0.805	0.50
175_P	340_T	0.804	0.49
69_V	284_L	0.804	0.49
157_A	220_N	0.804	0.49
168_A	309_E	0.799	0.49
102_F	398_V	0.798	0.49
79_E	82_E	0.798	0.49
180_H	239_S	0.798	0.49
224_A	248_E	0.796	0.49
490_L	509_R	0.795	0.49
359_R	511_R	0.794	0.49
226_V	367_F	0.794	0.49
399_L	412_H	0.793	0.49
496_G	514_G	0.791	0.48
299_G	323_E	0.789	0.48
232_V	248_E	0.787	0.48
429_V	445_T	0.785	0.48
245_Y	546_E	0.784	0.48
587_K	591_D	0.784	0.48
301_T	321_R	0.782	0.48
66_L	103_I	0.781	0.47
150_S	153_I	0.776	0.47
103_I	126_H	0.776	0.47
328_M	331_G	0.775	0.47
235_A	360_I	0.774	0.47
117_E	127_L	0.774	0.47
410_V	470_A	0.774	0.47
137_I	413_V	0.774	0.47
204_P	386_M	0.773	0.47
163_S	207_Q	0.772	0.47
372_G	411_G	0.772	0.47
243_R	446_L	0.771	0.47
142_I	145_P	0.770	0.46
291_V	295_S	0.766	0.46
453_S	471_E	0.766	0.46
169_A	207_Q	0.765	0.46
370_R	415_E	0.765	0.46
251_R	274_D	0.763	0.46
511_R	526_I	0.762	0.46
255_G	262_I	0.760	0.46
96_E	120_L	0.760	0.46
76_V	82_E	0.759	0.46
234_R	479_Y	0.758	0.45
361_P	367_F	0.758	0.45
501_L	601_R	0.757	0.45
178_R	328_M	0.756	0.45
142_I	147_H	0.756	0.45
479_Y	587_K	0.756	0.45
307_L	310_P	0.753	0.45
186_Q	345_E	0.751	0.45
151_P	159_M	0.751	0.45
151_P	434_F	0.750	0.45
248_E	350_L	0.748	0.45
491_H	510_A	0.748	0.45
428_S	448_D	0.747	0.44
112_L	127_L	0.746	0.44
446_L	537_R	0.746	0.44
444_G	454_S	0.745	0.44
249_E	272_G	0.743	0.44
225_L	367_F	0.743	0.44
414_L	442_I	0.743	0.44
425_D	451_F	0.742	0.44
495_K	512_E	0.742	0.44
226_V	485_M	0.741	0.44
417_L	477_I	0.740	0.44
224_A	422_G	0.738	0.44
486_V	502_T	0.738	0.44
123_D	126_H	0.737	0.44
116_E	527_G	0.734	0.43
353_V	511_R	0.734	0.43
304_P	344_G	0.733	0.43
287_P	527_G	0.731	0.43
109_E	126_H	0.730	0.43
118_E	127_L	0.730	0.43
525_V	534_L	0.729	0.43
525_V	537_R	0.727	0.43
398_V	473_F	0.726	0.43
89_I	128_E	0.724	0.43
217_E	226_V	0.719	0.42
537_R	553_C	0.718	0.42
495_K	499_Q	0.717	0.42
436_G	443_R	0.717	0.42
400_N	413_V	0.715	0.42
206_G	519_E	0.715	0.42
74_P	77_T	0.713	0.42
403_A	416_M	0.711	0.41
322_R	346_D	0.710	0.41
447_E	452_K	0.708	0.41
134_I	525_V	0.707	0.41
518_G	521_E	0.706	0.41
71_N	82_E	0.706	0.41
215_S	221_I	0.704	0.41
282_D	349_K	0.704	0.41
215_S	220_N	0.703	0.41
489_K	493_R	0.702	0.41
449_R	452_K	0.701	0.41
138_G	537_R	0.700	0.40
357_D	483_Y	0.698	0.40
383_Q	396_D	0.697	0.40
552_N	576_D	0.697	0.40
373_Q	409_T	0.696	0.40
251_R	312_D	0.696	0.40
80_E	93_D	0.696	0.40
508_G	513_G	0.695	0.40
416_M	475_G	0.695	0.40
484_H	489_K	0.695	0.40
139_A	510_A	0.694	0.40
139_A	386_M	0.694	0.40
450_G	460_Y	0.694	0.40
215_S	443_R	0.693	0.40
296_V	327_T	0.693	0.40
473_F	477_I	0.692	0.40
291_V	334_G	0.692	0.40
116_E	120_L	0.691	0.40
299_G	334_G	0.690	0.40
545_E	584_Y	0.689	0.40
413_V	416_M	0.687	0.39
537_R	550_C	0.687	0.39
290_K	335_V	0.687	0.39
390_Q	460_Y	0.686	0.39
509_R	528_H	0.685	0.39
129_I	336_V	0.685	0.39
96_E	474_V	0.685	0.39
137_I	517_V	0.681	0.39
254_G	510_A	0.681	0.39
212_A	396_D	0.680	0.39
84_V	233_E	0.680	0.39
112_L	123_D	0.679	0.39
186_Q	411_G	0.678	0.39
177_T	243_R	0.677	0.39
139_A	243_R	0.676	0.38
368_A	371_H	0.674	0.38
254_G	276_Y	0.672	0.38
102_F	106_E	0.671	0.38
216_Y	470_A	0.670	0.38
166_L	239_S	0.669	0.38
326_V	329_R	0.669	0.38
214_M	476_T	0.668	0.38
114_G	485_M	0.668	0.38
136_G	180_H	0.668	0.38
185_P	537_R	0.667	0.38
71_N	598_I	0.666	0.38
211_V	236_L	0.666	0.38
92_E	97_A	0.666	0.38
248_E	351_A	0.664	0.37
271_R	320_K	0.663	0.37
193_Q	385_D	0.662	0.37
162_Q	484_H	0.662	0.37
146_E	220_N	0.662	0.37
220_N	405_P	0.662	0.37
332_E	587_K	0.661	0.37
490_L	588_L	0.660	0.37
198_I	574_E	0.659	0.37
224_A	308_E	0.657	0.37
154_T	524_T	0.656	0.37
377_V	459_M	0.656	0.37
472_I	494_S	0.656	0.37
376_V	414_L	0.656	0.37
483_Y	587_K	0.655	0.37
287_P	431_G	0.655	0.37
106_E	591_D	0.655	0.37
159_M	486_V	0.655	0.37
584_Y	591_D	0.655	0.37
95_V	100_V	0.655	0.37
442_I	454_S	0.653	0.37
230_G	384_E	0.653	0.37
148_N	372_G	0.651	0.36
166_L	404_L	0.650	0.36
75_V	85_K	0.650	0.36
357_D	499_Q	0.650	0.36
249_E	348_S	0.649	0.36
343_E	347_G	0.649	0.36
78_Q	81_V	0.649	0.36
252_Y	506_T	0.648	0.36
408_M	491_H	0.648	0.36
421_A	424_L	0.647	0.36
298_L	382_P	0.645	0.36
399_L	404_L	0.644	0.36
251_R	256_Q	0.643	0.36
149_A	209_F	0.642	0.36
497_P	512_E	0.641	0.36
501_L	584_Y	0.640	0.36
390_Q	458_V	0.639	0.35
535_K	580_I	0.639	0.35
337_D	367_F	0.639	0.35
159_M	370_R	0.638	0.35
369_S	480_H	0.638	0.35
209_F	577_V	0.637	0.35
211_V	479_Y	0.636	0.35
129_I	287_P	0.635	0.35
403_A	484_H	0.635	0.35
109_E	249_E	0.634	0.35
150_S	156_G	0.634	0.35
240_H	356_R	0.633	0.35
173_I	176_D	0.631	0.35
460_Y	471_E	0.631	0.35
327_T	576_D	0.631	0.35
397_L	419_G	0.631	0.35
151_P	420_K	0.629	0.35
224_A	359_R	0.628	0.35
296_V	323_E	0.627	0.34
157_A	597_G	0.627	0.34
256_Q	262_I	0.627	0.34
410_V	445_T	0.626	0.34
416_M	420_K	0.626	0.34
427_R	445_T	0.625	0.34
150_S	225_L	0.625	0.34
119_E	127_L	0.625	0.34
384_E	398_V	0.624	0.34
135_F	145_P	0.623	0.34
420_K	446_L	0.623	0.34
149_A	409_T	0.622	0.34
68_V	105_A	0.622	0.34
71_N	437_E	0.622	0.34
522_R	537_R	0.621	0.34
333_D	357_D	0.620	0.34
484_H	493_R	0.619	0.34
525_V	533_V	0.619	0.34
179_Q	354_S	0.618	0.34
370_R	491_H	0.618	0.34
259_R	264_G	0.616	0.34
229_K	380_L	0.615	0.34
297_L	328_M	0.615	0.34
143_P	542_S	0.614	0.33
323_E	439_E	0.613	0.33
76_V	84_V	0.612	0.33
113_V	131_P	0.612	0.33
224_A	570_N	0.612	0.33
213_V	481_K	0.611	0.33
285_V	353_V	0.611	0.33
579_S	595_A	0.611	0.33
232_V	361_P	0.611	0.33
504_Q	513_G	0.610	0.33
98_G	114_G	0.610	0.33
527_G	532_M	0.610	0.33
215_S	335_V	0.609	0.33
396_D	476_T	0.608	0.33
456_K	470_A	0.608	0.33
220_N	404_L	0.606	0.33
592_E	596_L	0.605	0.33
300_K	481_K	0.604	0.33
190_V	472_I	0.604	0.33
355_V	363_L	0.604	0.33
76_V	86_N	0.604	0.33
301_T	597_G	0.603	0.33
191_N	196_E	0.603	0.33
145_P	205_A	0.602	0.33
213_V	369_S	0.600	0.32
251_R	281_D	0.599	0.32
153_I	480_H	0.598	0.32
537_R	551_G	0.598	0.32
215_S	477_I	0.596	0.32
77_T	89_I	0.596	0.32
335_V	527_G	0.595	0.32
102_F	114_G	0.595	0.32
497_P	502_T	0.594	0.32
148_N	507_E	0.594	0.32
531_A	577_V	0.594	0.32
335_V	390_Q	0.594	0.32
530_A	538_L	0.593	0.32
110_D	351_A	0.592	0.32
133_L	144_Y	0.592	0.32
576_D	601_R	0.591	0.32
225_L	379_H	0.591	0.32
585_A	592_E	0.591	0.32
164_L	182_L	0.591	0.32
549_V	604_L	0.591	0.32
426_G	450_G	0.591	0.32
427_R	437_E	0.591	0.32
67_L	87_G	0.590	0.32
224_A	363_L	0.589	0.32
226_V	439_E	0.588	0.31
281_D	574_E	0.587	0.31
361_P	485_M	0.585	0.31
224_A	485_M	0.584	0.31
134_I	154_T	0.583	0.31
240_H	459_M	0.583	0.31
253_P	322_R	0.583	0.31
296_V	414_L	0.582	0.31
491_H	508_G	0.582	0.31
109_E	400_N	0.581	0.31
417_L	429_V	0.581	0.31
169_A	202_D	0.581	0.31
66_L	128_E	0.580	0.31
122_T	281_D	0.580	0.31
213_V	233_E	0.580	0.31
196_E	451_F	0.580	0.31
229_K	382_P	0.579	0.31
295_S	336_V	0.575	0.30
451_F	457_E	0.574	0.30
199_G	397_L	0.574	0.30
104_D	136_G	0.573	0.30
311_E	319_Q	0.572	0.30
188_A	359_R	0.572	0.30
548_H	579_S	0.571	0.30
144_Y	411_G	0.571	0.30
80_E	426_G	0.569	0.30
504_Q	508_G	0.568	0.30
155_M	160_M	0.568	0.30
75_V	86_N	0.567	0.30
161_K	399_L	0.566	0.30
339_V	595_A	0.566	0.30
157_A	412_H	0.565	0.30
589_L	592_E	0.565	0.30
149_A	159_M	0.565	0.30
216_Y	399_L	0.563	0.30
309_E	423_S	0.563	0.30
300_K	303_P	0.563	0.30
450_G	485_M	0.562	0.30
301_T	602_L	0.562	0.30
479_Y	483_Y	0.562	0.30
505_P	542_S	0.561	0.29
171_Y	287_P	0.560	0.29
115_V	118_E	0.559	0.29
436_G	444_G	0.559	0.29
156_G	541_S	0.559	0.29
74_P	82_E	0.558	0.29
297_L	326_V	0.557	0.29
316_L	511_R	0.555	0.29
517_V	525_V	0.555	0.29
178_R	184_Y	0.555	0.29
210_V	395_P	0.554	0.29
103_I	248_E	0.553	0.29
143_P	371_H	0.552	0.29
378_G	420_K	0.552	0.29
69_V	109_E	0.551	0.29
162_Q	519_E	0.551	0.29
529_G	543_D	0.549	0.29
373_Q	523_D	0.548	0.29
104_D	587_K	0.548	0.29
326_V	353_V	0.547	0.28
74_P	196_E	0.545	0.28
93_D	96_E	0.545	0.28
338_T	393_V	0.545	0.28
85_K	318_P	0.545	0.28
286_N	295_S	0.544	0.28
146_E	149_A	0.544	0.28
76_V	81_V	0.544	0.28
140_G	171_Y	0.543	0.28
231_S	386_M	0.541	0.28
69_V	127_L	0.541	0.28
107_E	189_M	0.540	0.28
319_Q	324_T	0.540	0.28
97_A	447_E	0.540	0.28
119_E	144_Y	0.540	0.28
224_A	237_S	0.540	0.28
79_E	87_G	0.540	0.28
389_T	421_A	0.540	0.28
73_E	340_T	0.540	0.28
252_Y	257_E	0.538	0.28
357_D	396_D	0.538	0.28
342_M	517_V	0.537	0.28
405_P	434_F	0.536	0.28
395_P	459_M	0.536	0.28
75_V	309_E	0.535	0.28
324_T	339_V	0.535	0.28
347_G	577_V	0.534	0.28
224_A	486_V	0.533	0.27
473_F	485_M	0.532	0.27
220_N	412_H	0.532	0.27
281_D	580_I	0.531	0.27
123_D	244_T	0.531	0.27
171_Y	227_M	0.530	0.27
93_D	97_A	0.530	0.27
273_E	293_D	0.530	0.27
491_H	509_R	0.529	0.27
135_F	189_M	0.529	0.27
124_H	258_D	0.528	0.27
491_H	515_L	0.528	0.27
134_I	580_I	0.528	0.27
376_V	528_H	0.527	0.27
163_S	442_I	0.527	0.27
112_L	125_T	0.526	0.27
362_E	490_L	0.526	0.27
397_L	582_M	0.526	0.27
282_D	308_E	0.524	0.27
262_I	271_R	0.524	0.27
260_F	466_E	0.522	0.27
261_E	321_R	0.522	0.27
308_E	577_V	0.522	0.27
83_A	87_G	0.521	0.27
494_S	578_H	0.521	0.27
224_A	357_D	0.520	0.27
234_R	395_P	0.520	0.27
545_E	590_L	0.519	0.26
119_E	388_F	0.519	0.26
344_G	572_E	0.518	0.26
184_Y	473_F	0.518	0.26
450_G	537_R	0.518	0.26
397_L	428_S	0.517	0.26
347_G	470_A	0.517	0.26
81_V	198_I	0.517	0.26
284_L	298_L	0.517	0.26
247_G	576_D	0.516	0.26
590_L	602_L	0.516	0.26
548_H	577_V	0.516	0.26
294_S	324_T	0.515	0.26
104_D	125_T	0.515	0.26
413_V	455_G	0.514	0.26
168_A	207_Q	0.514	0.26
253_P	258_D	0.514	0.26
248_E	597_G	0.513	0.26
128_E	550_C	0.511	0.26
138_G	294_S	0.511	0.26
91_F	479_Y	0.511	0.26
418_G	429_V	0.511	0.26
403_A	456_K	0.510	0.26
188_A	472_I	0.509	0.26
294_S	423_S	0.508	0.26
147_H	378_G	0.508	0.26
255_G	344_G	0.507	0.26
163_S	417_L	0.507	0.26
253_P	257_E	0.507	0.26
192_T	457_E	0.506	0.26
90_D	97_A	0.505	0.26
593_M	603_E	0.505	0.26
272_G	277_T	0.504	0.25
593_M	600_P	0.504	0.25
315_G	319_Q	0.503	0.25
73_E	79_E	0.503	0.25
352_K	591_D	0.503	0.25
243_R	329_R	0.503	0.25
347_G	377_V	0.502	0.25
224_A	350_L	0.502	0.25
254_G	261_E	0.502	0.25
504_Q	514_G	0.501	0.25
147_H	531_A	0.501	0.25
410_V	490_L	0.501	0.25
388_F	453_S	0.501	0.25
85_K	340_T	0.500	0.25

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1twfB	2	0.9507	100	0.023	Contact Map
3h0gB	1	0.9803	100	0.025	Contact Map
4qiwB	1	0.9375	100	0.027	Contact Map
4aybB	1	0.9786	100	0.032	Contact Map
4c2mB	1	0.9227	100	0.132	Contact Map
2a6hC	1	0.9605	100	0.187	Contact Map
4yfkC	1	0.9556	100	0.203	Contact Map
2ly7A	1	0.2056	100	0.874	Contact Map
3woeA	1	0.1891	99.8	0.906	Contact Map
3tbiB	1	0.227	99.8	0.916	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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