GREMLIN Database
RL15 - 50S ribosomal protein L15
UniProt: P05971 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 153 (133)
Sequences: 451 (267)
Seq/√Len: 23.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
126_F141_A5.2291.00
94_A109_V5.1621.00
5_K8_Q3.7131.00
8_Q14_H2.9781.00
123_A126_F2.9681.00
54_R58_T2.9190.99
132_E136_G2.7680.99
129_A132_E2.6620.99
16_G22_R2.4060.98
109_V126_F2.2210.96
109_V123_A2.2180.96
54_R57_K2.1740.96
54_R62_V2.1240.95
33_R44_Y1.9260.92
93_D96_D1.8580.91
57_K62_V1.8110.90
131_V135_E1.8050.90
12_R21_N1.7760.89
95_R107_V1.7750.89
76_V79_E1.6780.86
58_T61_D1.6780.86
94_A126_F1.5630.81
123_A141_A1.5620.81
78_S82_V1.5410.81
92_V119_L1.5340.80
71_D74_I1.5320.80
115_L119_L1.5220.80
36_R47_V1.4940.78
5_K14_H1.4770.78
113_G133_L1.4630.77
34_A47_V1.4450.76
110_L127_S1.4210.75
128_D132_E1.4190.75
94_A107_V1.3980.73
53_K56_E1.3730.72
74_I78_S1.3420.70
14_H43_N1.3140.69
11_S16_G1.3120.69
54_R61_D1.3040.68
59_D67_V1.2830.67
46_D127_S1.2260.63
76_V80_S1.2230.63
18_T22_R1.1870.61
122_T142_V1.1830.60
118_Q136_G1.1670.59
8_Q13_T1.1400.57
78_S81_G1.1370.57
12_R26_G1.1160.56
85_E88_F1.1150.56
30_G113_G1.0770.53
59_D62_V1.0740.53
77_L118_Q1.0660.52
119_L128_D1.0480.51
44_Y142_V1.0330.50
108_K127_S1.0270.50
96_D104_A1.0260.50
4_K8_Q1.0040.48
109_V141_A0.9980.48
11_S14_H0.9960.47
85_E89_G0.9830.47
67_V81_G0.9820.46
67_V70_L0.9800.46
16_G21_N0.9700.46
45_E127_S0.9590.45
33_R42_H0.9570.45
42_H75_P0.9480.44
77_L83_A0.9410.44
7_R29_G0.9330.43
9_R23_R0.9280.43
54_R59_D0.9260.43
118_Q137_E0.9220.42
6_R18_T0.9130.42
85_E114_Q0.9120.42
10_G22_R0.9000.41
120_E132_E0.8980.41
13_T16_G0.8960.41
109_V115_L0.8910.40
121_V134_I0.8870.40
31_R51_G0.8850.40
107_V124_D0.8790.39
3_D8_Q0.8660.39
23_R139_G0.8580.38
70_L92_V0.8550.38
13_T72_E0.8490.37
67_V133_L0.8490.37
3_D7_R0.8410.37
86_T141_A0.8370.37
92_V137_E0.8370.37
53_K85_E0.8240.36
66_S127_S0.8120.35
37_K81_G0.8100.35
39_H68_Q0.7980.34
77_L81_G0.7920.34
23_R29_G0.7910.34
32_G51_G0.7900.34
6_R10_G0.7890.34
35_G139_G0.7800.33
88_F136_G0.7790.33
60_R124_D0.7770.33
6_R20_K0.7710.33
5_K43_N0.7690.32
19_H111_G0.7610.32
94_A141_A0.7580.32
86_T89_G0.7570.32
23_R138_G0.7540.31
89_G140_D0.7490.31
5_K121_V0.7410.31
3_D142_V0.7400.31
21_N36_R0.7380.31
17_G110_L0.7350.30
16_G27_N0.7330.30
8_Q126_F0.7320.30
6_R22_R0.7260.30
9_R18_T0.7230.30
19_H22_R0.7160.29
71_D92_V0.7160.29
84_E87_E0.7120.29
37_K44_Y0.7040.29
35_G130_A0.6920.28
75_P83_A0.6910.28
75_P81_G0.6900.28
106_V112_G0.6890.28
18_T21_N0.6870.28
37_K47_V0.6860.28
75_P78_S0.6840.27
40_E45_E0.6780.27
82_V87_E0.6770.27
12_R16_G0.6760.27
71_D77_L0.6760.27
54_R127_S0.6760.27
30_G130_A0.6700.27
78_S87_E0.6680.27
91_R136_G0.6650.26
38_K52_F0.6620.26
21_N27_N0.6620.26
61_D129_A0.6610.26
27_N123_A0.6610.26
78_S119_L0.6560.26
58_T62_V0.6540.26
3_D6_R0.6510.26
65_L109_V0.6500.26
104_A114_Q0.6490.26
33_R140_D0.6460.25
42_H93_D0.6420.25
55_P64_V0.6380.25
80_S83_A0.6340.25
75_P142_V0.6330.25
94_A104_A0.6330.25
81_G133_L0.6320.25
94_A106_V0.6290.24
94_A123_A0.6220.24
85_E119_L0.6220.24
36_R105_D0.6210.24
10_G23_R0.6180.24
108_K113_G0.6130.24
77_L88_F0.6120.24
10_G111_G0.5960.23
118_Q140_D0.5950.23
33_R112_G0.5950.23
55_P132_E0.5930.23
18_T138_G0.5900.23
80_S84_E0.5890.22
61_D136_G0.5870.22
66_S133_L0.5850.22
58_T137_E0.5810.22
40_E43_N0.5810.22
66_S112_G0.5740.22
87_E129_A0.5740.22
70_L78_S0.5710.22
88_F141_A0.5700.22
63_A135_E0.5700.22
90_Y94_A0.5680.21
37_K40_E0.5660.21
38_K55_P0.5650.21
42_H124_D0.5640.21
17_G108_K0.5520.21
93_D131_V0.5500.21
9_R121_V0.5470.20
10_G17_G0.5460.20
21_N123_A0.5440.20
23_R130_A0.5360.20
74_I92_V0.5340.20
35_G113_G0.5330.20
116_Y131_V0.5250.20
41_Q45_E0.5240.19
29_G138_G0.5240.19
38_K68_Q0.5180.19
50_S54_R0.5160.19
32_G35_G0.5140.19
75_P104_A0.5120.19
82_V125_A0.5100.19
66_S110_L0.5080.19
22_R27_N0.5080.19
15_G138_G0.5080.19
12_R55_P0.5070.19
84_E89_G0.5070.19
70_L73_D0.5050.19
54_R69_E0.5010.18
113_G139_G0.5010.18
81_G85_E0.5000.18
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j21L 1 0.8889 100 0.361 Contact Map
1vq8L 1 0.9477 100 0.372 Contact Map
4w20a 1 0.8824 100 0.374 Contact Map
4a17K 1 0.902 100 0.379 Contact Map
3zf7b 1 0.8824 100 0.391 Contact Map
1vx7O 1 0.8889 100 0.401 Contact Map
3j61a 1 0.8627 100 0.413 Contact Map
4ujrN 1 0.8889 100 0.418 Contact Map
3bboN 1 0.9542 99.9 0.565 Contact Map
3j7yM 1 0.9216 99.9 0.632 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0062 seconds.