GREMLIN Database
RL11 - 50S ribosomal protein L11
UniProt: P05969 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 163 (135)
Sequences: 2429 (987)
Seq/√Len: 85.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
33_A37_E3.7611.00
75_V133_V3.5821.00
95_D134_T3.0511.00
75_V96_L3.0411.00
40_D43_E2.9521.00
102_K106_E2.8951.00
98_I125_A2.5791.00
3_E27_T2.4691.00
71_T124_V2.4661.00
87_E91_N2.4561.00
97_S100_Q2.4151.00
102_K121_A2.4011.00
78_E103_T2.2421.00
22_P26_P2.1851.00
29_V56_Y2.1731.00
95_D136_E2.1701.00
50_V66_V2.1231.00
87_E90_E2.0891.00
5_I56_Y2.0281.00
79_A96_L1.7341.00
37_E41_Q1.7201.00
9_V20_L1.7161.00
89_Q92_F1.7081.00
48_T73_A1.7031.00
99_E102_K1.6891.00
83_T86_G1.5601.00
92_F134_T1.5571.00
101_L125_A1.5281.00
101_L121_A1.5181.00
13_Q46_D1.5171.00
32_Q36_Q1.4460.99
15_D35_V1.4350.99
98_I121_A1.3860.99
101_L124_V1.3660.99
4_T53_T1.3630.99
5_I27_T1.3240.99
53_T67_G1.3110.99
112_L120_A1.3100.99
114_A119_N1.2690.98
103_T106_E1.2670.98
10_A13_Q1.2520.98
85_S89_Q1.2410.98
99_E103_T1.2380.98
68_V110_P1.2370.98
19_P22_P1.2360.98
117_A121_A1.2160.98
109_K114_A1.1970.97
100_Q103_T1.1720.97
122_K125_A1.1620.97
121_A125_A1.1410.97
116_D119_N1.1410.97
86_G91_N1.1180.96
75_V79_A1.1090.96
109_K120_A1.1040.96
48_T77_D1.0900.96
73_A76_K1.0870.95
115_Y119_N1.0760.95
114_A120_A1.0690.95
79_A133_V1.0670.95
30_D33_A1.0660.95
76_K81_F1.0620.95
85_S91_N1.0510.95
98_I101_L1.0370.94
81_F133_V1.0360.94
53_T65_E1.0310.94
45_F49_E1.0180.94
96_L133_V0.9840.92
103_T107_Q0.9820.92
105_A117_A0.9760.92
45_F50_V0.9740.92
102_K117_A0.9720.92
26_P31_V0.9620.91
38_I53_T0.9440.91
75_V128_C0.9350.90
98_I102_K0.9260.90
10_A49_E0.9050.89
76_K83_T0.8970.88
72_A127_T0.8970.88
49_E73_A0.8950.88
79_A94_A0.8930.88
71_T96_L0.8930.88
68_V71_T0.8930.88
33_A36_Q0.8920.88
74_L107_Q0.8830.88
29_V61_S0.8560.86
78_E107_Q0.8480.85
94_A133_V0.8410.85
52_V66_V0.8330.84
78_E100_Q0.8310.84
9_V49_E0.8270.84
32_Q40_D0.8260.84
106_E117_A0.8160.83
98_I137_G0.8080.82
27_T60_G0.8030.82
57_E63_S0.8000.82
113_L123_E0.7930.81
37_E64_I0.7900.81
26_P29_V0.7860.81
119_N122_K0.7840.81
13_Q82_D0.7760.80
41_Q64_I0.7760.80
99_E137_G0.7730.80
77_D80_G0.7660.79
32_Q35_V0.7650.79
32_Q62_F0.7580.78
14_A21_G0.7570.78
106_E121_A0.7560.78
34_V38_I0.7430.77
25_G130_S0.7420.77
43_E46_D0.7390.76
5_I54_I0.7370.76
81_F93_V0.7320.76
72_A86_G0.7310.76
20_L23_E0.7250.75
27_T56_Y0.7250.75
72_A89_Q0.7240.75
118_R122_K0.7160.74
36_Q40_D0.7140.74
79_A93_V0.7120.74
5_I29_V0.7100.74
68_V109_K0.7030.73
20_L64_I0.6980.72
126_G130_S0.6980.72
78_E104_I0.6960.72
9_V38_I0.6940.72
13_Q43_E0.6820.71
85_S92_F0.6800.70
70_P131_L0.6740.70
86_G89_Q0.6640.69
38_I49_E0.6640.69
75_V104_I0.6620.68
38_I58_D0.6610.68
97_S136_E0.6600.68
76_K84_G0.6550.67
112_L123_E0.6540.67
41_Q66_V0.6510.67
96_L135_I0.6440.66
109_K112_L0.6360.65
94_A134_T0.6340.65
85_S88_P0.6310.65
7_V52_V0.6300.64
42_T66_V0.6270.64
13_Q47_G0.6200.63
37_E62_F0.6120.62
15_D31_V0.6120.62
69_P74_L0.6110.62
7_V20_L0.6090.62
83_T91_N0.6010.61
119_N123_E0.6000.61
65_E110_P0.5970.60
63_S66_V0.5940.60
118_R121_A0.5920.60
23_E56_Y0.5870.59
109_K113_L0.5860.59
45_F107_Q0.5860.59
32_Q37_E0.5860.59
113_L120_A0.5850.59
28_P60_G0.5800.58
25_G28_P0.5800.58
50_V69_P0.5800.58
51_P68_V0.5760.58
16_P54_I0.5750.58
22_P56_Y0.5730.57
37_E40_D0.5690.57
101_L115_Y0.5620.56
9_V31_V0.5610.56
33_A60_G0.5600.56
80_G100_Q0.5580.55
27_T127_T0.5550.55
116_D121_A0.5510.54
7_V22_P0.5510.54
60_G66_V0.5510.54
57_E61_S0.5500.54
79_A101_L0.5490.54
45_F48_T0.5460.54
32_Q43_E0.5390.53
89_Q93_V0.5380.53
12_G126_G0.5370.52
88_P92_F0.5370.52
9_V66_V0.5360.52
24_L29_V0.5300.52
99_E107_Q0.5290.51
16_P39_N0.5290.51
108_K111_D0.5280.51
102_K105_A0.5230.51
79_A135_I0.5210.50
96_L101_L0.5200.50
96_L104_I0.5200.50
22_P31_V0.5170.50
21_G25_G0.5160.50
66_V87_E0.5160.50
39_N108_K0.5130.49
38_I52_V0.5120.49
15_D19_P0.5120.49
58_D122_K0.5100.49
21_G51_P0.5090.49
34_V39_N0.5080.49
4_T58_D0.5060.48
11_G46_D0.5060.48
115_Y122_K0.5040.48
8_L70_P0.5000.48
31_V36_Q0.5000.48
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j21H 1 0.8098 100 0.042 Contact Map
1vq8I 1 0.4294 100 0.049 Contact Map
3j61K 1 0.7669 100 0.099 Contact Map
3zf7M 1 0.8098 100 0.112 Contact Map
4w22K 1 0.9141 100 0.113 Contact Map
3j7yJ 1 0.8282 100 0.119 Contact Map
3bboK 1 0.8344 100 0.134 Contact Map
3egvB 1 0.4601 100 0.139 Contact Map
4tp9I 1 0.0123 100 0.143 Contact Map
1mmsA 1 0.816 100 0.147 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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