O54610 - HALSA - GREMLIN Contacts

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O54610 - CydA

UniProt:	O54610	Sequences: MVPATLLSTVDLGWMALLSPEIASRMQFGWTISVHIIFASLSIGLAPFIIYFTWKDVRTNEQRYARLRSFWVKVFAVGFVMGTVTGIPMSFQFGTNFPQFATIAGELIGGPLAFEAKMAFFLEAVFLGVLLYGRERVADRTYVLSSVLVGVGAWLSGFWILVVNAWMQTPRGYEMVTRNGMEVAKLTDPVAAFLTPRMPWMYVHMMNASVISVALLVAGVSAYLVWKKPDADAWNSALKLAVVLLLVSAPFQAVHGDAYGRHVEDTQPQKFAAMEAHYETGSADLHLLAFPKSLDALTDPRTENLFTVSLPGIGSFLASGGDFDAEVIGLNEYEENPPVALVFWSFRFMVGLGFLFIGLALWGGYLTYRGRLTESTRYLKSMIAASPFGYAALLTGWYVTEIGRQPWVIQGELKTSEAVSSTLTGTEATLTLVGFVVLYIALILTALYVLKWLIRGELRSLGVQESSAGRWRGPLPWVTSDD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	482 (435)
Sequences:	2847 (1535)
Seq/√Len:	73.6

ECOLI - CYDA APPC
BACSU - CYDA YTHA
HALSA - O54610

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
188_D	191_A	6.376	1.00
292_K	305_L	5.324	1.00
408_V	418_A	5.171	1.00
219_G	386_S	4.562	1.00
253_A	357_I	4.541	1.00
319_S	325_A	4.338	1.00
279_E	331_N	4.108	1.00
316_F	323_F	3.958	1.00
289_A	304_N	3.894	1.00
144_L	148_L	3.866	1.00
292_K	301_R	3.714	1.00
257_D	261_R	3.064	1.00
354_F	358_G	2.947	1.00
207_N	255_H	2.941	1.00
261_R	321_G	2.850	1.00
176_V	179_N	2.827	1.00
242_V	363_G	2.826	1.00
60_N	139_D	2.810	1.00
257_D	321_G	2.794	1.00
282_S	326_E	2.722	1.00
426_T	430_L	2.664	1.00
215_L	245_L	2.627	1.00
376_T	380_K	2.568	1.00
429_T	433_V	2.543	1.00
366_L	378_Y	2.522	1.00
50_I	147_V	2.421	1.00
302_T	331_N	2.419	1.00
352_L	356_F	2.379	1.00
398_Y	402_I	2.350	1.00
286_H	309_S	2.304	1.00
312_G	323_F	2.297	1.00
286_H	343_F	2.251	1.00
269_Q	333_Y	2.234	1.00
302_T	336_N	2.214	1.00
21_E	419_V	2.204	1.00
335_E	414_K	2.169	1.00
57_V	143_V	2.162	1.00
304_N	307_T	2.144	1.00
377_R	380_K	2.129	1.00
280_T	332_E	2.124	1.00
51_Y	55_K	2.059	1.00
284_D	309_S	2.036	1.00
33_S	394_L	2.030	1.00
176_V	185_K	2.024	1.00
137_V	145_S	2.024	1.00
54_W	143_V	1.999	1.00
239_K	367_T	1.990	1.00
352_L	388_F	1.962	1.00
212_S	393_L	1.927	1.00
36_I	205_M	1.897	1.00
249_A	357_I	1.882	1.00
348_F	395_T	1.860	1.00
24_S	428_A	1.858	1.00
293_S	340_A	1.852	1.00
54_W	147_V	1.849	1.00
174_E	187_T	1.836	1.00
278_Y	304_N	1.830	1.00
341_L	402_I	1.820	1.00
19_S	22_I	1.810	1.00
414_K	417_E	1.803	1.00
358_G	362_W	1.797	1.00
451_K	455_R	1.789	1.00
207_N	251_F	1.758	1.00
363_G	378_Y	1.758	1.00
129_V	137_V	1.734	1.00
405_Q	415_T	1.682	1.00
359_L	385_A	1.681	1.00
211_I	249_A	1.669	1.00
34_V	443_I	1.664	1.00
362_W	366_L	1.652	1.00
62_Q	66_R	1.647	1.00
99_Q	102_T	1.640	1.00
30_W	436_V	1.637	1.00
355_L	385_A	1.625	1.00
20_P	24_S	1.621	0.99
33_S	398_Y	1.620	0.99
63_R	236_S	1.617	0.99
138_A	141_T	1.614	0.99
134_R	142_Y	1.612	0.99
104_A	108_I	1.608	0.99
26_M	432_L	1.605	0.99
253_A	354_F	1.597	0.99
328_I	332_E	1.587	0.99
221_S	237_A	1.573	0.99
359_L	381_S	1.569	0.99
190_V	193_F	1.517	0.99
49_I	68_R	1.510	0.99
366_L	375_S	1.497	0.99
67_L	237_A	1.494	0.99
322_D	325_A	1.465	0.99
226_W	376_T	1.464	0.99
52_F	67_L	1.451	0.99
74_V	216_L	1.447	0.99
316_F	321_G	1.442	0.99
218_A	242_V	1.439	0.99
74_V	450_L	1.439	0.99
351_G	355_L	1.439	0.99
49_I	146_S	1.438	0.99
338_P	402_I	1.431	0.99
69_S	134_R	1.431	0.99
280_T	326_E	1.423	0.99
437_V	441_A	1.419	0.99
173_Y	412_E	1.412	0.99
301_R	305_L	1.400	0.98
169_T	197_R	1.396	0.98
290_F	344_W	1.389	0.98
365_Y	368_Y	1.382	0.98
22_I	26_M	1.379	0.98
274_M	399_V	1.378	0.98
56_D	65_A	1.374	0.98
249_A	360_A	1.370	0.98
103_I	184_A	1.364	0.98
440_I	444_L	1.353	0.98
122_L	152_G	1.346	0.98
224_L	229_P	1.345	0.98
186_L	192_A	1.335	0.98
385_A	388_F	1.335	0.98
380_K	384_A	1.332	0.98
289_A	307_T	1.329	0.98
53_T	143_V	1.312	0.98
162_V	198_M	1.307	0.98
413_L	418_A	1.302	0.98
41_L	216_L	1.290	0.97
312_G	324_D	1.288	0.97
71_W	237_A	1.286	0.97
226_W	383_I	1.284	0.97
42_S	78_G	1.265	0.97
433_V	437_V	1.258	0.97
29_G	402_I	1.257	0.97
157_G	206_M	1.252	0.97
76_A	131_L	1.248	0.97
312_G	316_F	1.248	0.97
55_K	58_R	1.247	0.97
65_A	69_S	1.234	0.97
108_I	163_V	1.234	0.97
215_L	359_L	1.234	0.97
218_A	238_L	1.232	0.97
181_M	185_K	1.224	0.96
20_P	425_G	1.221	0.96
50_I	54_W	1.211	0.96
41_L	45_L	1.208	0.96
55_K	61_E	1.198	0.96
364_G	368_Y	1.197	0.96
239_K	243_V	1.196	0.96
30_W	432_L	1.195	0.96
214_A	241_A	1.195	0.96
293_S	338_P	1.191	0.96
43_I	209_S	1.189	0.96
223_Y	227_K	1.187	0.96
277_H	286_H	1.185	0.96
114_F	189_P	1.183	0.96
129_V	145_S	1.183	0.96
281_G	284_D	1.172	0.95
202_Y	206_M	1.172	0.95
319_S	322_D	1.169	0.95
161_L	198_M	1.162	0.95
48_F	240_L	1.155	0.95
24_S	423_L	1.151	0.95
218_A	241_A	1.144	0.95
47_P	150_G	1.144	0.95
300_P	303_E	1.144	0.95
448_Y	452_W	1.143	0.95
220_V	454_I	1.138	0.95
203_V	255_H	1.136	0.95
147_V	151_V	1.130	0.94
41_L	390_Y	1.128	0.94
271_F	327_V	1.125	0.94
215_L	356_F	1.125	0.94
154_W	206_M	1.124	0.94
214_A	245_L	1.122	0.94
264_E	318_A	1.116	0.94
48_F	244_L	1.104	0.94
430_L	434_G	1.100	0.94
249_A	253_A	1.100	0.94
208_A	393_L	1.087	0.93
226_W	380_K	1.080	0.93
264_E	271_F	1.073	0.93
351_G	354_F	1.071	0.93
238_L	382_M	1.066	0.93
149_V	153_A	1.060	0.92
391_A	395_T	1.056	0.92
286_H	289_A	1.050	0.92
362_W	377_R	1.049	0.92
51_Y	240_L	1.048	0.92
348_F	391_A	1.046	0.92
47_P	51_Y	1.037	0.91
271_F	274_M	1.036	0.91
205_M	208_A	1.035	0.91
235_N	239_K	1.034	0.91
366_L	371_R	1.031	0.91
269_Q	330_L	1.026	0.91
338_P	341_L	1.026	0.91
200_W	262_H	1.025	0.91
130_L	146_S	1.023	0.91
169_T	262_H	1.020	0.91
246_L	364_G	1.020	0.91
359_L	388_F	1.015	0.91
52_F	240_L	1.014	0.91
158_F	162_V	1.012	0.90
245_L	360_A	1.010	0.90
53_T	146_S	1.009	0.90
53_T	134_R	1.007	0.90
361_L	365_Y	1.007	0.90
434_G	438_L	0.999	0.90
277_H	327_V	0.999	0.90
173_Y	187_T	0.997	0.90
213_V	389_G	0.993	0.90
56_D	134_R	0.993	0.90
197_R	266_T	0.991	0.90
65_A	134_R	0.988	0.89
378_Y	382_M	0.987	0.89
68_R	134_R	0.986	0.89
226_W	379_L	0.984	0.89
67_L	233_A	0.983	0.89
318_A	327_V	0.980	0.89
319_S	324_D	0.974	0.89
431_T	434_G	0.968	0.88
371_R	374_E	0.968	0.88
21_E	416_S	0.967	0.88
140_R	144_L	0.966	0.88
141_T	144_L	0.964	0.88
231_A	235_N	0.961	0.88
358_G	361_L	0.961	0.88
215_L	382_M	0.956	0.88
176_V	181_M	0.952	0.88
54_W	58_R	0.951	0.88
199_P	203_V	0.950	0.87
104_A	409_I	0.949	0.87
200_W	258_A	0.949	0.87
355_L	358_G	0.945	0.87
143_V	147_V	0.939	0.87
285_L	317_L	0.934	0.87
262_H	266_T	0.931	0.86
47_P	50_I	0.929	0.86
278_Y	331_N	0.927	0.86
218_A	382_M	0.926	0.86
282_S	328_I	0.923	0.86
223_Y	383_I	0.923	0.86
359_L	382_M	0.922	0.86
222_A	379_L	0.920	0.86
247_V	251_F	0.919	0.86
277_H	328_I	0.912	0.85
62_Q	65_A	0.911	0.85
285_L	350_V	0.909	0.85
26_M	30_W	0.907	0.85
293_S	300_P	0.899	0.84
233_A	458_L	0.896	0.84
290_F	306_F	0.892	0.84
150_G	154_W	0.892	0.84
280_T	328_I	0.891	0.84
32_I	89_M	0.891	0.84
139_D	143_V	0.890	0.84
197_R	201_M	0.890	0.84
278_Y	293_S	0.888	0.84
23_A	429_T	0.871	0.82
248_S	252_Q	0.868	0.82
211_I	252_Q	0.867	0.82
355_L	359_L	0.867	0.82
243_V	364_G	0.866	0.82
68_R	72_V	0.866	0.82
312_G	325_A	0.865	0.82
281_G	326_E	0.860	0.82
148_L	152_G	0.858	0.82
158_F	193_F	0.857	0.81
286_H	307_T	0.855	0.81
203_V	207_N	0.855	0.81
216_L	390_Y	0.849	0.81
77_V	453_L	0.848	0.81
408_V	413_L	0.848	0.81
314_G	327_V	0.848	0.81
169_T	196_P	0.846	0.81
135_E	139_D	0.846	0.81
263_V	274_M	0.845	0.81
280_T	329_G	0.845	0.81
290_F	305_L	0.844	0.80
175_M	184_A	0.843	0.80
281_G	309_S	0.841	0.80
254_V	258_A	0.840	0.80
355_L	381_S	0.840	0.80
151_V	155_L	0.838	0.80
424_T	427_E	0.835	0.80
271_F	314_G	0.835	0.80
98_P	421_S	0.831	0.79
23_A	432_L	0.828	0.79
425_G	428_A	0.825	0.79
363_G	382_M	0.824	0.79
426_T	429_T	0.823	0.79
57_V	140_R	0.821	0.79
206_M	210_V	0.820	0.79
70_F	457_E	0.816	0.78
100_F	106_E	0.815	0.78
210_V	248_S	0.809	0.78
211_I	245_L	0.808	0.77
451_K	454_I	0.807	0.77
423_L	428_A	0.804	0.77
100_F	104_A	0.803	0.77
92_Q	97_F	0.802	0.77
243_V	367_T	0.802	0.77
61_E	66_R	0.802	0.77
277_H	281_G	0.802	0.77
441_A	445_T	0.801	0.77
356_F	385_A	0.801	0.77
341_L	398_Y	0.800	0.77
452_W	456_G	0.798	0.77
62_Q	139_D	0.794	0.76
425_G	429_T	0.794	0.76
249_A	353_G	0.792	0.76
66_R	459_R	0.791	0.76
104_A	166_W	0.791	0.76
246_L	361_L	0.788	0.76
289_A	306_F	0.787	0.76
293_S	339_V	0.787	0.76
292_K	303_E	0.786	0.76
430_L	433_V	0.784	0.75
433_V	436_V	0.784	0.75
162_V	400_T	0.783	0.75
310_L	313_I	0.783	0.75
342_V	345_S	0.782	0.75
61_E	232_D	0.782	0.75
342_V	398_Y	0.781	0.75
345_S	399_V	0.780	0.75
288_L	306_F	0.779	0.75
64_Y	67_L	0.778	0.75
251_F	255_H	0.775	0.75
290_F	340_A	0.773	0.74
342_V	399_V	0.771	0.74
283_A	325_A	0.768	0.74
408_V	415_T	0.766	0.74
64_Y	458_L	0.766	0.74
66_R	230_D	0.763	0.73
423_L	427_E	0.762	0.73
424_T	428_A	0.761	0.73
217_V	241_A	0.760	0.73
228_K	376_T	0.760	0.73
263_V	400_T	0.760	0.73
222_A	238_L	0.759	0.73
107_L	186_L	0.757	0.73
246_L	360_A	0.755	0.73
211_I	356_F	0.755	0.73
174_E	185_K	0.754	0.72
200_W	259_Y	0.752	0.72
364_G	367_T	0.752	0.72
134_R	146_S	0.751	0.72
36_I	393_L	0.751	0.72
57_V	139_D	0.751	0.72
78_G	216_L	0.749	0.72
224_L	457_E	0.746	0.72
48_F	217_V	0.746	0.72
345_S	395_T	0.744	0.71
141_T	145_S	0.742	0.71
40_S	108_I	0.742	0.71
314_G	317_L	0.742	0.71
126_F	145_S	0.741	0.71
331_N	336_N	0.739	0.71
54_W	57_V	0.738	0.71
209_S	252_Q	0.738	0.71
119_A	156_S	0.737	0.71
264_E	328_I	0.737	0.71
93_F	112_L	0.736	0.71
227_K	384_A	0.734	0.70
34_V	38_F	0.733	0.70
333_Y	336_N	0.732	0.70
72_V	130_L	0.730	0.70
47_P	154_W	0.727	0.70
136_R	455_R	0.727	0.70
88_P	439_Y	0.724	0.69
283_A	329_G	0.724	0.69
209_S	393_L	0.723	0.69
312_G	322_D	0.721	0.69
269_Q	410_Q	0.720	0.69
77_V	449_V	0.719	0.69
100_F	107_L	0.718	0.69
165_A	201_M	0.718	0.69
165_A	195_T	0.716	0.69
362_W	365_Y	0.716	0.69
362_W	381_S	0.715	0.68
365_Y	369_R	0.714	0.68
243_V	247_V	0.714	0.68
244_L	248_S	0.713	0.68
271_F	318_A	0.711	0.68
74_V	453_L	0.711	0.68
289_A	309_S	0.708	0.68
419_V	428_A	0.708	0.68
225_V	231_A	0.701	0.67
129_V	449_V	0.699	0.67
43_I	154_W	0.698	0.67
286_H	304_N	0.695	0.66
29_G	341_L	0.695	0.66
326_E	332_E	0.695	0.66
308_V	313_I	0.695	0.66
47_P	210_V	0.695	0.66
279_E	326_E	0.692	0.66
292_K	304_N	0.690	0.66
447_L	451_K	0.690	0.66
357_I	361_L	0.689	0.66
114_F	159_W	0.685	0.65
288_L	307_T	0.684	0.65
301_R	307_T	0.683	0.65
435_F	442_L	0.682	0.65
301_R	306_F	0.679	0.64
242_V	364_G	0.678	0.64
293_S	301_R	0.677	0.64
278_Y	336_N	0.677	0.64
197_R	262_H	0.677	0.64
110_G	186_L	0.676	0.64
114_F	118_M	0.673	0.64
63_R	67_L	0.672	0.64
58_R	61_E	0.672	0.64
235_N	373_T	0.671	0.64
165_A	198_M	0.671	0.64
427_E	430_L	0.670	0.63
328_I	333_Y	0.668	0.63
137_V	141_T	0.668	0.63
119_A	155_L	0.668	0.63
292_K	302_T	0.668	0.63
280_T	327_V	0.667	0.63
55_K	64_Y	0.667	0.63
153_A	210_V	0.667	0.63
51_Y	59_T	0.665	0.63
60_N	370_G	0.664	0.63
230_D	457_E	0.663	0.63
315_S	327_V	0.663	0.63
47_P	147_V	0.663	0.63
354_F	362_W	0.661	0.62
53_T	57_V	0.660	0.62
94_G	109_G	0.659	0.62
356_F	388_F	0.658	0.62
19_S	26_M	0.657	0.62
315_S	325_A	0.657	0.62
440_I	443_I	0.657	0.62
126_F	152_G	0.657	0.62
340_A	344_W	0.655	0.62
338_P	342_V	0.652	0.61
84_V	411_G	0.652	0.61
119_A	160_I	0.651	0.61
303_E	306_F	0.650	0.61
335_E	407_W	0.649	0.61
224_L	454_I	0.648	0.61
381_S	385_A	0.647	0.61
38_F	84_V	0.643	0.60
359_L	378_Y	0.642	0.60
387_P	391_A	0.641	0.60
23_A	428_A	0.640	0.60
134_R	457_E	0.639	0.60
98_P	101_A	0.637	0.60
89_M	95_T	0.636	0.59
46_A	162_V	0.636	0.59
418_A	421_S	0.636	0.59
255_H	258_A	0.635	0.59
313_I	354_F	0.635	0.59
260_G	347_R	0.634	0.59
436_V	440_I	0.633	0.59
122_L	148_L	0.632	0.59
342_V	402_I	0.632	0.59
24_S	419_V	0.632	0.59
413_L	417_E	0.631	0.59
107_L	173_Y	0.631	0.59
224_L	234_W	0.629	0.59
107_L	184_A	0.627	0.58
217_V	244_L	0.626	0.58
215_L	352_L	0.625	0.58
352_L	392_A	0.623	0.58
46_A	49_I	0.622	0.58
89_M	92_Q	0.621	0.58
216_L	450_L	0.619	0.57
172_G	192_A	0.617	0.57
52_F	68_R	0.616	0.57
211_I	248_S	0.614	0.57
106_E	181_M	0.613	0.57
249_A	352_L	0.611	0.56
428_A	432_L	0.610	0.56
316_F	322_D	0.609	0.56
300_P	305_L	0.609	0.56
277_H	314_G	0.609	0.56
174_E	186_L	0.607	0.56
214_A	248_S	0.607	0.56
278_Y	307_T	0.605	0.56
276_A	347_R	0.605	0.56
154_W	210_V	0.604	0.56
53_T	65_A	0.603	0.55
91_F	116_A	0.602	0.55
242_V	366_L	0.602	0.55
378_Y	381_S	0.601	0.55
151_V	190_V	0.601	0.55
318_A	321_G	0.601	0.55
442_L	446_A	0.601	0.55
375_S	379_L	0.599	0.55
350_V	392_A	0.599	0.55
90_S	163_V	0.599	0.55
55_K	240_L	0.599	0.55
431_T	454_I	0.598	0.55
63_R	232_D	0.595	0.54
264_E	325_A	0.594	0.54
73_K	456_G	0.594	0.54
55_K	59_T	0.593	0.54
336_N	414_K	0.592	0.54
208_A	252_Q	0.592	0.54
166_W	192_A	0.592	0.54
78_G	90_S	0.592	0.54
179_N	185_K	0.591	0.54
446_A	450_L	0.590	0.54
287_L	310_L	0.585	0.53
352_L	395_T	0.585	0.53
99_Q	413_L	0.584	0.53
191_A	194_L	0.583	0.53
303_E	307_T	0.582	0.53
130_L	142_Y	0.582	0.53
20_P	419_V	0.580	0.53
101_A	104_A	0.580	0.53
276_A	289_A	0.578	0.52
159_W	193_F	0.578	0.52
211_I	214_A	0.578	0.52
224_L	458_L	0.577	0.52
59_T	64_Y	0.577	0.52
238_L	379_L	0.577	0.52
100_F	167_M	0.576	0.52
61_E	64_Y	0.576	0.52
161_L	205_M	0.575	0.52
59_T	68_R	0.575	0.52
279_E	334_E	0.574	0.52
362_W	375_S	0.574	0.52
196_P	262_H	0.572	0.52
461_L	464_Q	0.571	0.51
453_L	456_G	0.571	0.51
218_A	385_A	0.571	0.51
45_L	216_L	0.571	0.51
250_P	357_I	0.570	0.51
233_A	237_A	0.570	0.51
289_A	343_F	0.567	0.51
367_T	370_G	0.567	0.51
383_I	386_S	0.566	0.51
66_R	460_S	0.565	0.51
111_P	192_A	0.564	0.51
173_Y	184_A	0.563	0.50
276_A	330_L	0.563	0.50
18_L	429_T	0.562	0.50
154_W	158_F	0.559	0.50
246_L	250_P	0.559	0.50
24_S	420_S	0.559	0.50
110_G	189_P	0.558	0.50
284_D	307_T	0.558	0.50
128_G	131_L	0.557	0.50
136_R	452_W	0.557	0.50
24_S	75_F	0.557	0.50
42_S	81_M	0.556	0.50
31_T	89_M	0.556	0.50
39_A	108_I	0.554	0.49
72_V	134_R	0.554	0.49
309_S	374_E	0.553	0.49
50_I	146_S	0.553	0.49
148_L	151_V	0.551	0.49
430_L	436_V	0.550	0.49
259_Y	262_H	0.549	0.49
66_R	233_A	0.549	0.49
282_S	319_S	0.548	0.49
172_G	191_A	0.548	0.49
328_I	335_E	0.548	0.49
245_L	356_F	0.547	0.48
49_I	75_F	0.547	0.48
304_N	339_V	0.545	0.48
343_F	347_R	0.545	0.48
279_E	301_R	0.544	0.48
66_R	461_L	0.543	0.48
19_S	429_T	0.542	0.48
78_G	390_Y	0.541	0.48
429_T	434_G	0.541	0.48
34_V	81_M	0.541	0.48
283_A	323_F	0.540	0.48
448_Y	451_K	0.539	0.47
169_T	266_T	0.539	0.47
34_V	85_T	0.539	0.47
230_D	458_L	0.538	0.47
36_I	389_G	0.538	0.47
376_T	379_L	0.538	0.47
281_G	445_T	0.537	0.47
341_L	345_S	0.537	0.47
273_A	339_V	0.535	0.47
86_G	123_E	0.535	0.47
143_V	146_S	0.535	0.47
419_V	450_L	0.535	0.47
100_F	108_I	0.534	0.47
228_K	231_A	0.534	0.47
311_P	346_F	0.534	0.47
44_G	246_L	0.533	0.47
67_L	71_W	0.533	0.47
380_K	383_I	0.532	0.47
216_L	454_I	0.532	0.47
138_A	144_L	0.532	0.47
350_V	354_F	0.531	0.46
66_R	73_K	0.531	0.46
304_N	309_S	0.531	0.46
69_S	139_D	0.530	0.46
106_E	184_A	0.530	0.46
376_T	441_A	0.529	0.46
247_V	363_G	0.529	0.46
291_P	344_W	0.528	0.46
201_M	257_D	0.527	0.46
124_A	393_L	0.526	0.46
31_T	435_F	0.526	0.46
48_F	241_A	0.526	0.46
189_P	343_F	0.526	0.46
87_I	125_V	0.525	0.46
31_T	92_Q	0.525	0.46
201_M	400_T	0.524	0.46
227_K	231_A	0.524	0.46
82_G	401_E	0.524	0.46
215_L	388_F	0.523	0.45
34_V	37_I	0.522	0.45
234_W	237_A	0.522	0.45
272_A	314_G	0.521	0.45
47_P	244_L	0.520	0.45
309_S	318_A	0.519	0.45
260_G	317_L	0.518	0.45
130_L	389_G	0.518	0.45
77_V	446_A	0.517	0.45
277_H	435_F	0.516	0.45
41_L	52_F	0.516	0.45
196_P	266_T	0.514	0.44
249_A	356_F	0.514	0.44
429_T	432_L	0.514	0.44
407_W	458_L	0.513	0.44
77_V	450_L	0.513	0.44
395_T	398_Y	0.511	0.44
61_E	236_S	0.511	0.44
387_P	458_L	0.510	0.44
224_L	227_K	0.509	0.44
272_A	332_E	0.509	0.44
43_I	47_P	0.507	0.44
412_E	416_S	0.506	0.43
211_I	352_L	0.506	0.43
256_G	346_F	0.506	0.43
158_F	198_M	0.506	0.43
232_D	236_S	0.505	0.43
76_A	130_L	0.505	0.43
278_Y	302_T	0.505	0.43
288_L	344_W	0.505	0.43
158_F	202_Y	0.504	0.43
72_V	77_V	0.504	0.43
118_M	155_L	0.504	0.43
48_F	100_F	0.503	0.43
151_V	341_L	0.503	0.43
92_Q	116_A	0.503	0.43
165_A	252_Q	0.502	0.43
140_R	143_V	0.502	0.43
212_S	398_Y	0.502	0.43
301_R	304_N	0.502	0.43
124_A	453_L	0.501	0.43
91_F	94_G	0.501	0.43
230_D	460_S	0.500	0.43
65_A	135_E	0.500	0.43
106_E	185_K	0.500	0.43
164_N	401_E	0.500	0.43

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mk7A	1	0.4585	44.8	0.977	Contact Map
4xp4A	1	0.4357	33.2	0.979	Contact Map
3ukmA	2	0.444	26.2	0.98	Contact Map
3w4tA	1	0.7718	22	0.981	Contact Map
3s8fA	1	0.9212	21.8	0.981	Contact Map
2a65A	2	0.4295	16.4	0.982	Contact Map
4tphA	2	0.7552	13.1	0.983	Contact Map
2f95B	2	0.11	11	0.983	Contact Map
4ltoA	3	0.249	10.3	0.983	Contact Map
3hzqA	3	0.1494	9.4	0.984	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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