GREMLIN Database
O54573 - SojC
UniProt: O54573 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 312 (246)
Sequences: 14435 (9123)
Seq/√Len: 581.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
111_D151_Y4.2691.00
245_P272_S3.9051.00
47_A155_V3.7851.00
57_H278_G3.3321.00
59_H153_F2.9301.00
54_L153_F2.9241.00
46_I273_I2.9081.00
33_S173_T2.9021.00
259_G262_S2.7991.00
30_R175_N2.5571.00
62_L151_Y2.4891.00
181_A216_M2.4621.00
216_M246_N2.4511.00
221_I224_Q2.4121.00
63_L72_A2.3141.00
48_V72_A2.3001.00
75_G185_E2.2401.00
47_A63_L2.2181.00
105_D111_D2.2161.00
56_T274_T2.1291.00
34_V50_L2.0751.00
53_Q261_I2.0601.00
53_Q277_Y2.0451.00
213_V276_A2.0341.00
51_A63_L2.0171.00
249_R252_D2.0101.00
46_I213_V2.0011.00
231_L235_N1.9981.00
60_D152_D1.8921.00
218_D246_N1.8441.00
229_Q233_R1.8431.00
74_V188_S1.8071.00
59_H281_K1.7201.00
175_N210_L1.6911.00
214_P228_R1.6851.00
66_L169_A1.6821.00
230_L234_L1.6531.00
55_A110_F1.6521.00
54_L155_V1.6491.00
247_F269_D1.6491.00
228_R232_E1.6481.00
242_D279_E1.6291.00
242_D276_A1.6211.00
100_T150_E1.6211.00
57_H274_T1.6201.00
31_A156_T1.6141.00
51_A155_V1.6091.00
88_G91_E1.5671.00
34_V177_V1.5651.00
48_V75_G1.5561.00
50_L280_R1.5421.00
33_S158_S1.5231.00
98_D101_S1.5141.00
66_L156_T1.4931.00
76_L110_F1.4881.00
59_H152_D1.4871.00
55_A109_E1.4601.00
50_L277_Y1.4311.00
217_L243_R1.3901.00
241_Q279_E1.3861.00
29_S154_I1.3861.00
177_V213_V1.3671.00
66_L89_I1.3571.00
34_V47_A1.3541.00
175_N208_D1.3481.00
78_F112_I1.3361.00
51_A72_A1.3221.00
71_H189_G1.3181.00
166_T169_A1.3171.00
48_V76_L1.3031.00
239_S283_L1.2931.00
57_H281_K1.2911.00
176_L198_I1.2911.00
258_S263_P1.2901.00
182_P214_P1.2881.00
99_P113_L1.2821.00
249_R264_T1.2801.00
244_I269_D1.2781.00
230_L233_R1.2711.00
267_I270_R1.2591.00
223_Q226_Q1.2581.00
35_C193_T1.2561.00
42_G215_N1.2481.00
46_I215_N1.2341.00
139_K142_V1.2211.00
87_E91_E1.2191.00
248_A252_D1.2011.00
117_E192_R1.1861.00
183_G186_A1.1721.00
271_T274_T1.1621.00
30_R174_S1.1431.00
51_A110_F1.1401.00
175_N211_A1.1361.00
53_Q274_T1.1091.00
275_K279_E1.1031.00
250_I269_D1.0921.00
147_L150_E1.0881.00
112_I117_E1.0861.00
153_F281_K1.0841.00
46_I50_L1.0831.00
62_L103_V1.0831.00
228_R231_L1.0791.00
165_L169_A1.0681.00
135_S139_K1.0651.00
247_F267_I1.0651.00
89_I92_V1.0631.00
164_R169_A1.0611.00
70_G73_S1.0561.00
240_L243_R1.0531.00
136_A140_R1.0511.00
44_S72_A1.0361.00
123_E163_S1.0361.00
278_G282_P1.0311.00
268_R271_T1.0281.00
204_H207_V1.0281.00
54_L61_V1.0251.00
215_N273_I1.0211.00
106_T112_I1.0171.00
229_Q232_E1.0141.00
137_L141_E1.0131.00
54_L277_Y1.0071.00
131_V135_S0.9941.00
274_T278_G0.9931.00
185_E254_E0.9881.00
275_K278_G0.9881.00
272_S275_K0.9861.00
35_C158_S0.9791.00
52_R56_T0.9781.00
183_G251_T0.9771.00
34_V46_I0.9761.00
71_H185_E0.9731.00
97_A102_V0.9731.00
60_D150_E0.9721.00
256_V263_P0.9651.00
145_P148_G0.9641.00
258_S262_S0.9571.00
261_I274_T0.9571.00
56_T262_S0.9541.00
158_S169_A0.9541.00
136_A139_K0.9541.00
31_A154_I0.9521.00
87_E97_A0.9491.00
231_L234_L0.9411.00
141_E145_P0.9371.00
76_L112_I0.9331.00
101_S104_Y0.9311.00
111_D149_D0.9291.00
32_V280_R0.9251.00
70_G115_S0.9191.00
244_I272_S0.9191.00
49_N52_R0.9181.00
247_F268_R0.9181.00
44_S75_G0.9081.00
64_I156_T0.9071.00
90_G125_E0.9071.00
102_V113_L0.9051.00
68_P165_L0.9031.00
32_V153_F0.9031.00
103_V111_D0.8901.00
214_P217_L0.8901.00
276_A280_R0.8891.00
232_E235_N0.8891.00
52_R110_F0.8891.00
34_V155_V0.8881.00
219_G222_D0.8871.00
230_L235_N0.8811.00
260_D270_R0.8721.00
92_V102_V0.8691.00
195_E199_A0.8691.00
49_N261_I0.8651.00
97_A101_S0.8641.00
45_T250_I0.8631.00
53_Q57_H0.8621.00
31_A148_G0.8591.00
32_V175_N0.8571.00
56_T261_I0.8531.00
252_D256_V0.8461.00
265_P270_R0.8441.00
210_L284_L0.8421.00
137_L140_R0.8391.00
239_S279_E0.8291.00
179_P215_N0.8291.00
41_V186_A0.8231.00
218_D227_D0.8151.00
64_I154_I0.8031.00
140_R144_E0.8031.00
264_T267_I0.7971.00
62_L154_I0.7951.00
178_L194_I0.7871.00
37_L197_Q0.7801.00
30_R153_F0.7781.00
30_R210_L0.7781.00
131_V137_L0.7731.00
100_T104_Y0.7711.00
104_Y107_E0.7701.00
58_D109_E0.7691.00
133_Q136_A0.7641.00
153_F284_L0.7611.00
122_V126_I0.7581.00
63_L76_L0.7581.00
50_L276_A0.7581.00
268_R272_S0.7571.00
269_D272_S0.7571.00
175_N284_L0.7561.00
52_R261_I0.7551.00
53_Q273_I0.7511.00
228_R243_R0.7501.00
178_L190_L0.7471.00
182_P217_L0.7431.00
107_E262_S0.7421.00
228_R234_L0.7401.00
164_R171_V0.7391.00
229_Q243_R0.7321.00
177_V280_R0.7321.00
35_C166_T0.7311.00
182_P224_Q0.7261.00
66_L165_L0.7231.00
46_I179_P0.7211.00
124_R127_V0.7161.00
38_K43_K0.7161.00
181_A186_A0.7141.00
166_T170_L0.7131.00
211_A240_L0.7131.00
31_A174_S0.7081.00
45_T254_E0.7071.00
43_K160_A0.7041.00
74_V184_N0.7041.00
245_P268_R0.7031.00
224_Q227_D0.7021.00
233_R236_S0.6971.00
214_P231_L0.6971.00
90_G94_F0.6941.00
49_N273_I0.6891.00
49_N259_G0.6891.00
69_N163_S0.6891.00
36_M41_V0.6871.00
73_S114_P0.6871.00
266_G271_T0.6861.00
70_G116_S0.6861.00
164_R168_N0.6851.00
61_V110_F0.6791.00
248_A251_T0.6791.00
92_V113_L0.6781.00
47_A72_A0.6761.00
121_Q124_R0.6761.00
231_L236_S0.6731.00
191_E234_L0.6711.00
261_I270_R0.6711.00
124_R164_R0.6711.00
279_E283_L0.6691.00
100_T145_P0.6691.00
103_V151_Y0.6681.00
60_D111_D0.6671.00
137_L142_V0.6651.00
168_N171_V0.6641.00
134_P137_L0.6641.00
104_Y114_P0.6631.00
130_D134_P0.6611.00
139_K143_V0.6611.00
253_W260_D0.6601.00
271_T275_K0.6591.00
270_R274_T0.6581.00
163_S166_T0.6551.00
111_D114_P0.6541.00
167_D197_Q0.6501.00
180_L212_L0.6451.00
53_Q270_R0.6431.00
52_R259_G0.6401.00
151_Y154_I0.6371.00
232_E236_S0.6351.00
127_V130_D0.6351.00
131_V134_P0.6331.00
73_S116_S0.6311.00
61_V155_V0.6301.00
89_I113_L0.6281.00
253_W263_P0.6271.00
228_R235_N0.6271.00
103_V113_L0.6261.00
174_S206_D0.6261.00
144_E148_G0.6261.00
148_G174_S0.6231.00
220_R223_Q0.6221.00
222_D225_T0.6221.00
61_V152_D0.6211.00
44_S71_H0.6211.00
71_H188_S0.6201.00
52_R262_S0.6201.00
265_P274_T0.6181.00
133_Q140_R0.6141.00
87_E101_S0.6121.00
234_L237_H0.6041.00
166_T171_V0.6041.00
232_E241_Q0.6011.00
100_T103_V0.6001.00
155_V280_R0.5981.00
69_N160_A0.5961.00
29_S150_E0.5931.00
38_K185_E0.5921.00
250_I254_E0.5911.00
92_V99_P0.5911.00
91_E96_E0.5891.00
74_V185_E0.5881.00
244_I276_A0.5881.00
53_Q56_T0.5861.00
252_D263_P0.5851.00
30_R59_H0.5831.00
135_S138_L0.5831.00
184_N188_S0.5801.00
101_S105_D0.5791.00
228_R236_S0.5761.00
71_H74_V0.5761.00
221_I248_A0.5751.00
46_I244_I0.5751.00
61_V153_F0.5741.00
169_A173_T0.5731.00
178_L209_V0.5721.00
229_Q235_N0.5701.00
162_R166_T0.5701.00
47_A51_A0.5701.00
35_C170_L0.5671.00
62_L111_D0.5661.00
38_K41_V0.5630.99
191_E195_E0.5570.99
184_N255_A0.5560.99
31_A173_T0.5550.99
214_P243_R0.5530.99
232_E243_R0.5510.99
29_S148_G0.5500.99
279_E282_P0.5490.99
122_V125_E0.5490.99
111_D150_E0.5480.99
72_A112_I0.5470.99
277_Y281_K0.5450.99
33_S169_A0.5440.99
260_D269_D0.5420.99
164_R167_D0.5390.99
58_D265_P0.5390.99
156_T169_A0.5390.99
52_R55_A0.5350.99
147_L151_Y0.5340.99
88_G116_S0.5340.99
32_V210_L0.5330.99
103_V147_L0.5330.99
60_D151_Y0.5230.99
273_I276_A0.5190.99
183_G246_N0.5170.99
138_L143_V0.5160.99
223_Q251_T0.5150.99
30_R284_L0.5120.99
107_E111_D0.5120.99
195_E200_P0.5100.99
225_T229_Q0.5100.99
158_S166_T0.5100.99
32_V155_V0.5090.99
88_G92_V0.5090.99
211_A239_S0.5080.99
226_Q229_Q0.5080.99
132_F136_A0.5080.99
94_F97_A0.5070.99
186_A190_L0.5070.99
280_R284_L0.5060.99
241_Q275_K0.5040.99
33_S176_L0.5030.99
265_P271_T0.5030.99
49_N260_D0.5030.99
242_D275_K0.5020.99
217_L228_R0.5010.99
212_L238_N0.5000.99
176_L207_V0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4pfsA 1 0.7853 100 0.365 Contact Map
3ez9A 2 0.7885 100 0.381 Contact Map
3ez2A 2 0.9199 100 0.385 Contact Map
3pg5A 2 0.7372 100 0.392 Contact Map
1wcv1 2 0.7724 100 0.394 Contact Map
4rz3A 2 0.7628 100 0.399 Contact Map
2ozeA 2 0.8846 100 0.4 Contact Map
1g3qA 1 0.7532 100 0.402 Contact Map
1hyqA 1 0.7404 100 0.404 Contact Map
3ea0A 2 0.7532 100 0.407 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0093 seconds.