GREMLIN Database
ARSA - Putative arsenical pump-driving ATPase
UniProt: O52027 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 644 (562)
Sequences: 347 (240)
Seq/√Len: 10.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
556_Q562_E4.9261.00
45_D293_S4.7361.00
528_D531_R4.7191.00
432_D435_D4.5141.00
19_T205_S4.2610.99
359_I567_V4.2540.99
568_A593_L3.8250.98
98_Q102_E3.6450.98
545_M596_I3.5590.97
36_S170_L3.5130.97
449_E453_E3.3890.96
335_E370_A3.3220.96
422_Q464_E3.2730.96
67_Q77_D3.2400.95
493_E527_Q3.1800.95
417_E420_R3.1440.95
493_E499_K3.0870.94
417_E421_T3.0150.93
538_M596_I3.0150.93
338_V372_Y2.9780.93
106_A110_D2.9220.92
51_L87_I2.9200.92
342_E372_Y2.8990.92
101_I113_I2.8400.91
359_I607_A2.7450.89
123_P494_L2.6930.88
210_G217_I2.6620.88
348_F460_M2.6470.87
337_L346_L2.4970.84
94_E98_Q2.4620.83
281_L285_E2.4370.82
63_D260_E2.3910.81
499_K527_Q2.3910.81
48_Y145_V2.3150.79
416_L458_E2.2890.78
363_T535_A2.2220.76
91_V94_E2.2110.76
375_L408_A2.1980.75
431_Y435_D2.1730.74
379_T525_T2.1700.74
41_T612_E2.1330.73
375_L469_Y2.1260.73
83_S143_Y2.1120.72
120_L489_L2.0710.70
344_R347_F2.0540.70
107_L112_E2.0280.69
220_I237_L2.0180.68
194_A495_P2.0180.68
86_E157_I1.9920.67
415_A465_K1.9750.67
574_E577_G1.9650.66
377_V480_F1.9590.66
180_P458_E1.9440.65
415_A418_E1.9420.65
282_Q296_G1.9260.65
467_V522_V1.9160.64
180_P412_Q1.9130.64
535_A567_V1.9080.64
143_Y324_F1.9040.64
424_L449_E1.8820.63
69_I86_E1.8710.62
140_S203_R1.8450.61
165_D415_A1.8420.61
373_E476_D1.8230.60
132_D497_D1.7860.59
217_I267_V1.7740.58
242_Y567_V1.7600.57
346_L479_V1.7420.57
61_L86_E1.7230.56
536_F540_P1.7130.55
86_E260_E1.6910.54
117_E181_A1.6900.54
505_G508_T1.6890.54
210_G216_S1.6760.54
333_V605_M1.6720.53
116_V416_L1.6670.53
369_E621_R1.6660.53
344_R477_I1.6610.53
21_F197_T1.6600.53
503_D540_P1.6490.52
180_P448_V1.6480.52
45_D584_N1.6470.52
496_S522_V1.6420.52
239_V269_S1.6350.52
126_E527_Q1.6290.51
216_S239_V1.6200.51
41_T79_V1.6190.51
377_V568_A1.6190.51
132_D171_E1.6180.51
215_S239_V1.6160.51
100_T175_S1.6100.50
412_Q458_E1.6080.50
117_E460_M1.5850.49
246_S479_V1.5820.49
62_S260_E1.5820.49
220_I286_I1.5800.49
571_L574_E1.5770.49
159_L180_P1.5630.48
467_V524_E1.5490.48
573_P590_A1.5480.48
345_Y519_Y1.5420.47
57_P547_E1.5420.47
296_G473_D1.5350.47
361_S389_F1.5300.47
499_K502_M1.5300.47
71_H133_N1.5280.47
104_M116_V1.5180.46
552_A563_T1.5110.46
347_F477_I1.5110.46
65_F139_D1.5030.46
225_S230_L1.4860.45
169_E536_F1.4730.44
540_P574_E1.4610.44
62_S86_E1.4590.44
74_T100_T1.4500.43
430_M435_D1.4340.42
507_L510_G1.4340.42
194_A345_Y1.4250.42
98_Q105_R1.4240.42
36_S174_G1.4130.41
467_V496_S1.4080.41
48_Y242_Y1.4070.41
255_G343_T1.4010.41
117_E415_A1.3990.41
165_D293_S1.3860.40
464_E508_T1.3820.40
117_E449_E1.3740.40
525_T531_R1.3710.40
345_Y464_E1.3690.40
112_E460_M1.3590.39
338_V370_A1.3590.39
73_V83_S1.3560.39
65_F531_R1.3520.39
104_M126_E1.3490.39
109_G116_V1.3440.38
496_S524_E1.3430.38
328_T332_A1.3420.38
239_V593_L1.3380.38
86_E174_G1.3330.38
65_F260_E1.3260.38
174_G177_C1.3240.38
193_R218_D1.3190.37
366_S370_A1.3180.37
188_K416_L1.3120.37
213_E527_Q1.3090.37
345_Y527_Q1.3090.37
65_F243_L1.3070.37
408_A469_Y1.3040.37
147_V212_P1.3020.37
440_D448_V1.3010.37
108_L191_Y1.2970.36
141_P201_E1.2860.36
130_A241_G1.2820.36
488_T547_E1.2790.36
63_D546_M1.2780.36
81_N334_A1.2760.35
588_Q597_S1.2750.35
167_N474_G1.2700.35
62_S65_F1.2680.35
337_L536_F1.2630.35
221_E270_T1.2610.35
65_F579_N1.2570.35
61_L157_I1.2520.34
63_D86_E1.2510.34
188_K191_Y1.2490.34
109_G191_Y1.2430.34
126_E522_V1.2410.34
412_Q448_V1.2410.34
106_A501_F1.2390.34
87_I159_L1.2330.34
285_E542_F1.2330.34
281_L416_L1.2280.33
64_I191_Y1.2270.33
519_Y527_Q1.2240.33
552_A556_Q1.2230.33
101_I106_A1.2170.33
614_P620_L1.2090.33
174_G606_L1.2080.33
90_D379_T1.2080.33
57_P488_T1.2070.33
379_T480_F1.2040.32
143_Y146_V1.1990.32
453_E502_M1.1960.32
132_D585_R1.1880.32
467_V521_E1.1880.32
342_E409_R1.1870.32
169_E225_S1.1800.32
448_V458_E1.1750.31
146_V418_E1.1720.31
224_A235_Q1.1710.31
470_F523_I1.1680.31
362_T616_G1.1670.31
36_S606_L1.1660.31
86_E609_L1.1650.31
215_S289_L1.1600.31
427_V522_V1.1530.30
431_Y448_V1.1430.30
175_S586_R1.1430.30
100_T161_E1.1430.30
243_L257_R1.1420.30
224_A234_S1.1420.30
146_V421_T1.1410.30
474_G521_E1.1410.30
109_G181_A1.1390.30
186_D548_A1.1390.30
135_V613_E1.1370.30
109_G460_M1.1370.30
267_V271_F1.1310.30
117_E130_A1.1300.30
496_S527_Q1.1300.30
140_S362_T1.1300.30
126_E188_K1.1250.29
372_Y432_D1.1200.29
522_V527_Q1.1160.29
203_R324_F1.1110.29
504_L507_L1.1110.29
201_E207_A1.1110.29
87_I525_T1.1080.29
103_P191_Y1.1070.29
49_D182_A1.1060.29
123_P159_L1.1050.29
86_E104_M1.1040.29
362_T620_L1.1020.29
572_L610_R1.1010.28
123_P412_Q1.0980.28
41_T45_D1.0950.28
159_L458_E1.0930.28
53_V574_E1.0930.28
251_P611_Q1.0920.28
366_S479_V1.0910.28
524_E592_Y1.0870.28
104_M522_V1.0810.28
36_S592_Y1.0800.28
348_F519_Y1.0780.28
385_L546_M1.0740.27
139_D194_A1.0720.27
62_S546_M1.0660.27
103_P108_L1.0650.27
283_P420_R1.0630.27
123_P282_Q1.0600.27
291_L477_I1.0530.27
146_V228_A1.0520.27
116_V480_F1.0510.27
19_T236_L1.0470.26
63_D592_Y1.0460.26
95_E170_L1.0450.26
34_T361_S1.0430.26
171_E286_I1.0390.26
521_E528_D1.0380.26
98_Q195_I1.0370.26
368_A603_P1.0330.26
97_R500_G1.0320.26
521_E524_E1.0310.26
359_I535_A1.0300.26
228_A581_F1.0250.26
138_M170_L1.0240.26
75_A252_F1.0200.26
71_H385_L1.0200.26
522_V592_Y1.0190.25
242_Y278_T1.0180.25
101_I560_G1.0160.25
471_E523_I1.0150.25
112_E115_T1.0130.25
86_E213_E1.0120.25
138_M563_T1.0110.25
283_P425_D1.0110.25
182_A257_R1.0070.25
467_V527_Q0.9990.25
65_F76_I0.9990.25
110_D114_Q0.9980.25
87_I345_Y0.9970.25
538_M545_M0.9950.25
62_S157_I0.9910.25
103_P117_E0.9910.25
68_D201_E0.9910.25
414_R568_A0.9870.24
185_D420_R0.9810.24
100_T173_G0.9790.24
71_H295_V0.9790.24
41_T68_D0.9770.24
146_V593_L0.9770.24
185_D536_F0.9750.24
117_E165_D0.9740.24
200_D267_V0.9700.24
470_F570_Y0.9640.24
109_G586_R0.9640.24
20_E45_D0.9610.24
336_E603_P0.9590.23
217_I263_V0.9580.23
146_V567_V0.9570.23
433_E502_M0.9570.23
427_V467_V0.9560.23
182_A531_R0.9540.23
111_E232_I0.9540.23
139_D492_L0.9530.23
428_R431_Y0.9520.23
214_S473_D0.9520.23
112_E117_E0.9500.23
104_M609_L0.9480.23
492_L547_E0.9460.23
143_Y390_E0.9460.23
130_A165_D0.9440.23
61_L464_E0.9420.23
104_M213_E0.9420.23
108_L188_K0.9400.23
65_F206_F0.9400.23
157_I174_G0.9380.23
347_F533_S0.9370.23
472_E476_D0.9340.23
52_L194_A0.9310.23
207_A548_A0.9310.23
388_I496_S0.9310.23
159_L448_V0.9300.22
220_I570_Y0.9280.22
91_V293_S0.9270.22
73_V86_E0.9240.22
66_N78_D0.9240.22
553_M621_R0.9220.22
383_A409_R0.9200.22
101_I117_E0.9170.22
116_V550_R0.9170.22
210_G239_V0.9130.22
64_I109_G0.9130.22
327_F404_N0.9120.22
63_D550_R0.9110.22
594_E598_E0.9110.22
418_E497_D0.9090.22
76_I185_D0.9080.22
575_D586_R0.9080.22
181_A191_Y0.9050.22
120_L495_P0.9040.22
379_T523_I0.9030.22
180_P563_T0.9030.22
159_L412_Q0.9020.22
224_A470_F0.9020.22
174_G592_Y0.9020.22
66_N607_A0.9010.22
64_I181_A0.9000.22
84_A529_P0.8980.21
53_V585_R0.8980.21
453_E465_K0.8970.21
619_D623_F0.8970.21
165_D174_G0.8960.21
620_L623_F0.8950.21
379_T497_D0.8920.21
435_D448_V0.8910.21
123_P281_L0.8910.21
302_G332_A0.8890.21
76_I453_E0.8890.21
113_I117_E0.8880.21
256_K527_Q0.8870.21
418_E449_E0.8860.21
37_C488_T0.8860.21
42_W542_F0.8860.21
116_V460_M0.8850.21
361_S388_I0.8850.21
207_A334_A0.8840.21
37_C57_P0.8760.21
348_F522_V0.8740.21
137_F180_P0.8700.21
283_P417_E0.8700.21
103_P109_G0.8690.21
181_A460_M0.8680.21
109_G117_E0.8650.20
296_G365_V0.8620.20
341_E530_S0.8620.20
123_P190_D0.8610.20
113_I216_S0.8600.20
41_T575_D0.8590.20
416_L495_P0.8580.20
366_S500_G0.8580.20
174_G577_G0.8570.20
188_K296_G0.8570.20
49_D259_D0.8550.20
148_F451_E0.8530.20
61_L174_G0.8530.20
105_R191_Y0.8520.20
365_V372_Y0.8510.20
480_F523_I0.8490.20
143_Y473_D0.8490.20
449_E460_M0.8480.20
72_E372_Y0.8470.20
385_L389_F0.8470.20
102_E286_I0.8470.20
194_A485_T0.8460.20
36_S531_R0.8460.20
97_R101_I0.8440.20
189_A241_G0.8440.20
329_D362_T0.8440.20
165_D465_K0.8430.20
358_T478_V0.8430.20
51_L608_P0.8420.20
71_H253_F0.8420.20
334_A568_A0.8410.20
81_N571_L0.8410.20
217_I423_V0.8410.20
414_R418_E0.8400.20
193_R342_E0.8390.20
130_A415_A0.8380.20
473_D480_F0.8370.20
21_F435_D0.8360.20
229_E290_E0.8350.20
69_I164_S0.8340.20
180_P416_L0.8320.19
81_N510_G0.8300.19
292_L405_L0.8300.19
225_S528_D0.8300.19
617_L621_R0.8290.19
362_T366_S0.8290.19
467_V592_Y0.8250.19
91_V279_Y0.8250.19
345_Y473_D0.8240.19
225_S535_A0.8240.19
245_E267_V0.8240.19
117_E424_L0.8220.19
580_A585_R0.8210.19
107_L460_M0.8210.19
104_M112_E0.8200.19
256_K568_A0.8190.19
235_Q465_K0.8190.19
496_S606_L0.8180.19
232_I596_I0.8170.19
41_T289_L0.8170.19
123_P132_D0.8160.19
595_E600_F0.8150.19
348_F475_Y0.8150.19
112_E379_T0.8150.19
295_V572_L0.8140.19
203_R213_E0.8140.19
335_E479_V0.8140.19
21_F492_L0.8120.19
83_S110_D0.8110.19
212_P228_A0.8090.19
159_L469_Y0.8090.19
412_Q563_T0.8060.19
259_D435_D0.8060.19
45_D100_T0.8050.19
165_D220_I0.8050.19
409_R494_L0.8050.19
505_G510_G0.8040.19
611_Q615_V0.8030.19
61_L205_S0.8030.19
189_A598_E0.8020.19
136_D283_P0.7990.19
421_T425_D0.7980.19
264_I346_L0.7970.19
420_R528_D0.7960.18
165_D460_M0.7950.18
428_R435_D0.7930.18
41_T113_I0.7920.18
108_L502_M0.7920.18
270_T322_V0.7910.18
132_D216_S0.7890.18
107_L507_L0.7890.18
237_L497_D0.7890.18
113_I588_Q0.7880.18
182_A600_F0.7870.18
167_N500_G0.7860.18
496_S521_E0.7860.18
505_G550_R0.7850.18
495_P581_F0.7840.18
65_F546_M0.7840.18
81_N392_P0.7830.18
86_E522_V0.7820.18
107_L286_I0.7810.18
181_A570_Y0.7810.18
202_S331_D0.7810.18
282_Q416_L0.7800.18
61_L213_E0.7800.18
40_A52_L0.7780.18
137_F428_R0.7770.18
120_L161_E0.7750.18
220_I348_F0.7720.18
404_N504_L0.7720.18
157_I205_S0.7700.18
50_T168_A0.7680.18
344_R458_E0.7680.18
161_E285_E0.7650.18
87_I464_E0.7630.18
67_Q76_I0.7590.17
372_Y404_N0.7590.17
415_A449_E0.7590.17
106_A181_A0.7590.17
165_D237_L0.7560.17
106_A449_E0.7560.17
62_S565_V0.7550.17
524_E527_Q0.7540.17
285_E586_R0.7540.17
62_S592_Y0.7530.17
90_D213_E0.7520.17
65_F257_R0.7520.17
363_T598_E0.7510.17
37_C547_E0.7500.17
88_D596_I0.7490.17
260_E480_F0.7490.17
147_V192_E0.7480.17
297_G346_L0.7480.17
290_E346_L0.7480.17
101_I147_V0.7470.17
85_I388_I0.7470.17
167_N407_A0.7460.17
61_L260_E0.7460.17
147_V330_A0.7450.17
75_A340_V0.7450.17
120_L194_A0.7430.17
64_I103_P0.7430.17
519_Y524_E0.7420.17
431_Y493_E0.7420.17
86_E244_P0.7400.17
605_M608_P0.7400.17
319_E553_M0.7400.17
161_E502_M0.7390.17
422_Q426_H0.7390.17
345_Y496_S0.7370.17
105_R108_L0.7370.17
20_E170_L0.7350.17
53_V292_L0.7350.17
574_E586_R0.7350.17
132_D418_E0.7330.17
49_D267_V0.7320.17
306_T587_A0.7300.17
61_L104_M0.7290.17
577_G580_A0.7260.17
84_A428_R0.7250.17
146_V318_N0.7240.17
146_V408_A0.7240.17
161_E489_L0.7230.17
77_D594_E0.7230.17
251_P305_A0.7230.17
341_E590_A0.7210.16
345_Y522_V0.7210.16
406_D472_E0.7200.16
53_V137_F0.7200.16
110_D225_S0.7190.16
64_I108_L0.7190.16
369_E578_D0.7180.16
182_A285_E0.7180.16
37_C84_A0.7170.16
363_T510_G0.7170.16
66_N200_D0.7160.16
407_A552_A0.7140.16
616_G620_L0.7130.16
537_V567_V0.7120.16
210_G363_T0.7110.16
529_P535_A0.7100.16
252_F586_R0.7100.16
289_L385_L0.7100.16
292_L407_A0.7090.16
180_P431_Y0.7090.16
171_E337_L0.7080.16
273_Q304_E0.7080.16
147_V427_V0.7060.16
49_D568_A0.7050.16
53_V406_D0.7050.16
363_T594_E0.7050.16
568_A598_E0.7050.16
501_F606_L0.7030.16
247_V477_I0.7030.16
63_D157_I0.7030.16
104_M467_V0.7020.16
181_A195_I0.7020.16
104_M524_E0.7010.16
243_L344_R0.7010.16
607_A617_L0.7010.16
111_E337_L0.7000.16
132_D197_T0.6970.16
115_T458_E0.6930.16
217_I453_E0.6930.16
65_F69_I0.6900.16
79_V375_L0.6880.16
200_D432_D0.6870.16
206_F213_E0.6870.16
173_G592_Y0.6860.16
361_S477_I0.6850.16
116_V234_S0.6850.16
70_G86_E0.6850.16
201_E340_V0.6850.16
427_V524_E0.6850.16
76_I113_I0.6850.16
52_L282_Q0.6840.16
24_F279_Y0.6840.16
237_L415_A0.6840.16
64_I288_G0.6830.16
126_E496_S0.6820.16
178_I183_S0.6810.15
170_L345_Y0.6800.15
403_A502_M0.6800.15
257_R261_Q0.6780.15
412_Q494_L0.6770.15
330_A362_T0.6760.15
51_L88_D0.6760.15
49_D203_R0.6740.15
68_D346_L0.6730.15
251_P577_G0.6730.15
177_C222_R0.6720.15
61_L609_L0.6710.15
35_V238_V0.6700.15
412_Q416_L0.6690.15
37_C195_I0.6680.15
101_I110_D0.6680.15
63_D73_V0.6680.15
458_E533_S0.6660.15
169_E176_T0.6650.15
361_S383_A0.6650.15
537_V574_E0.6650.15
36_S230_L0.6640.15
180_P533_S0.6630.15
494_L533_S0.6610.15
428_R448_V0.6610.15
132_D600_F0.6600.15
135_V346_L0.6600.15
616_G623_F0.6600.15
165_D497_D0.6590.15
117_E191_Y0.6590.15
35_V286_I0.6560.15
20_E111_E0.6560.15
528_D567_V0.6520.15
116_V592_Y0.6520.15
159_L177_C0.6510.15
63_D565_V0.6500.15
109_G112_E0.6500.15
499_K563_T0.6480.15
280_P430_M0.6470.15
170_L504_L0.6460.15
265_D433_E0.6450.15
112_E165_D0.6450.15
84_A435_D0.6450.15
535_A619_D0.6440.15
568_A612_E0.6440.15
61_L186_D0.6440.15
112_E474_G0.6410.15
333_V573_P0.6410.15
499_K519_Y0.6390.15
596_I605_M0.6390.15
295_V328_T0.6390.15
216_S480_F0.6390.15
139_D424_L0.6380.14
331_D370_A0.6350.14
175_S289_L0.6340.14
81_N347_F0.6340.14
388_I477_I0.6330.14
66_N169_E0.6320.14
136_D608_P0.6320.14
191_Y501_F0.6270.14
174_G505_G0.6260.14
146_V417_E0.6250.14
37_C112_E0.6250.14
495_P546_M0.6250.14
51_L548_A0.6210.14
76_I495_P0.6190.14
552_A600_F0.6170.14
500_G528_D0.6170.14
260_E550_R0.6160.14
200_D221_E0.6160.14
297_G434_K0.6160.14
116_V510_G0.6150.14
146_V260_E0.6150.14
185_D540_P0.6150.14
109_G348_F0.6140.14
130_A460_M0.6140.14
62_S69_I0.6140.14
100_T285_E0.6140.14
90_D159_L0.6130.14
542_F572_L0.6120.14
365_V431_Y0.6090.14
407_A473_D0.6090.14
86_E205_S0.6080.14
36_S197_T0.6080.14
221_E268_E0.6070.14
102_E507_L0.6070.14
138_M259_D0.6060.14
332_A610_R0.6060.14
132_D556_Q0.6040.14
480_F525_T0.6040.14
500_G531_R0.6040.14
146_V423_V0.6040.14
36_S429_E0.6030.14
170_L174_G0.6030.14
236_L260_E0.6010.14
169_E177_C0.6010.14
36_S40_A0.5990.14
71_H346_L0.5970.14
427_V496_S0.5960.14
598_E618_D0.5950.14
99_E458_E0.5940.14
618_D621_R0.5940.14
237_L473_D0.5940.14
104_M550_R0.5930.13
57_P492_L0.5930.13
201_E267_V0.5930.13
504_L508_T0.5920.13
422_Q449_E0.5920.13
90_D420_R0.5920.13
113_I469_Y0.5910.13
61_L505_G0.5910.13
347_F468_S0.5900.13
256_K282_Q0.5900.13
187_K253_F0.5880.13
86_E173_G0.5850.13
51_L333_V0.5850.13
161_E613_E0.5840.13
247_V580_A0.5830.13
495_P499_K0.5810.13
20_E189_A0.5800.13
282_Q540_P0.5800.13
233_S323_D0.5800.13
417_E424_L0.5760.13
534_F583_E0.5760.13
126_E467_V0.5740.13
553_M567_V0.5740.13
359_I606_L0.5730.13
254_E553_M0.5730.13
107_L415_A0.5720.13
519_Y609_L0.5710.13
196_D424_L0.5700.13
111_E195_I0.5700.13
73_V157_I0.5700.13
34_T536_F0.5700.13
84_A135_V0.5700.13
294_D497_D0.5690.13
266_R275_A0.5690.13
73_V137_F0.5660.13
88_D229_E0.5660.13
141_P218_D0.5660.13
552_A599_R0.5650.13
87_I546_M0.5650.13
99_E137_F0.5640.13
37_C170_L0.5630.13
69_I157_I0.5610.13
189_A212_P0.5610.13
86_E523_I0.5600.13
281_L286_I0.5590.13
135_V171_E0.5590.13
61_L69_I0.5580.13
385_L595_E0.5580.13
112_E290_E0.5580.13
157_I260_E0.5580.13
243_L260_E0.5570.13
53_V564_S0.5560.13
426_H429_E0.5560.13
359_I537_V0.5560.13
181_A492_L0.5560.13
577_G600_F0.5560.13
169_E208_F0.5540.13
37_C206_F0.5540.13
191_Y420_R0.5530.13
112_E415_A0.5530.13
502_M527_Q0.5530.13
369_E610_R0.5530.13
104_M496_S0.5520.13
87_I173_G0.5520.13
167_N434_K0.5520.13
200_D359_I0.5510.13
100_T146_V0.5490.13
187_K409_R0.5480.13
406_D572_L0.5480.13
202_S329_D0.5470.13
323_D530_S0.5470.13
497_D562_E0.5470.13
412_Q431_Y0.5460.12
334_A527_Q0.5460.12
504_L509_K0.5440.12
64_I105_R0.5430.12
137_F533_S0.5430.12
377_V489_L0.5430.12
616_G619_D0.5420.12
493_E561_I0.5410.12
428_R432_D0.5410.12
404_N594_E0.5400.12
210_G553_M0.5400.12
473_D613_E0.5390.12
77_D210_G0.5380.12
428_R601_D0.5380.12
87_I608_P0.5380.12
116_V508_T0.5370.12
86_E467_V0.5370.12
142_E146_V0.5370.12
168_A284_G0.5360.12
302_G390_E0.5360.12
61_L550_R0.5360.12
289_L346_L0.5350.12
556_Q601_D0.5350.12
94_E110_D0.5330.12
171_E254_E0.5310.12
330_A359_I0.5300.12
546_M592_Y0.5280.12
221_E404_N0.5270.12
143_Y332_A0.5270.12
49_D572_L0.5260.12
251_P568_A0.5260.12
415_A581_F0.5250.12
101_I596_I0.5250.12
196_D322_V0.5240.12
265_D275_A0.5240.12
51_L563_T0.5240.12
189_A429_E0.5240.12
138_M564_S0.5230.12
173_G610_R0.5230.12
86_E164_S0.5220.12
191_Y586_R0.5220.12
549_Y595_E0.5210.12
99_E453_E0.5210.12
287_A565_V0.5210.12
370_A594_E0.5210.12
108_L501_F0.5200.12
488_T492_L0.5200.12
251_P297_G0.5190.12
213_E609_L0.5180.12
348_F379_T0.5170.12
176_T222_R0.5160.12
157_I609_L0.5140.12
542_F592_Y0.5130.12
255_G623_F0.5130.12
522_V542_F0.5120.12
237_L460_M0.5120.12
261_Q579_N0.5110.12
107_L267_V0.5110.12
203_R612_E0.5100.12
428_R440_D0.5100.12
593_L596_I0.5100.12
143_Y273_Q0.5100.12
279_Y340_V0.5090.12
252_F535_A0.5090.12
147_V426_H0.5080.12
571_L582_F0.5080.12
187_K465_K0.5080.12
406_D580_A0.5080.12
112_E130_A0.5080.12
51_L525_T0.5070.12
139_D453_E0.5070.12
392_P568_A0.5070.12
332_A389_F0.5050.12
259_D365_V0.5050.12
333_V565_V0.5040.12
114_Q196_D0.5040.12
137_F412_Q0.5040.12
76_I587_A0.5030.12
73_V570_Y0.5030.12
531_R592_Y0.5020.12
349_T534_F0.5010.12
157_I519_Y0.5010.12
135_V175_S0.5000.12
102_E592_Y0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ihuA 3 0.8307 100 0.667 Contact Map
3io3A 2 0.3525 100 0.82 Contact Map
2wojA 2 0.4627 100 0.82 Contact Map
3iqwA 2 0.396 100 0.822 Contact Map
2wooA 5 0.4441 100 0.831 Contact Map
3igfA 2 0.486 100 0.859 Contact Map
3zq6A 2 0.4379 100 0.868 Contact Map
3ug7A 4 0.4488 100 0.87 Contact Map
3kjhA 2 0.368 99.8 0.93 Contact Map
4jlvA 1 0.2842 99.8 0.934 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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